Mus musculus

32 known processes

Fancl

Fanconi anemia, complementation group L

(Aliases: gcd,AW554273,Phf9,B230118H11Rik,Pog,2010322C19Rik)

Fancl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleobase containing small molecule metabolic process GO:0055086 352 0.052
cellular amine metabolic process GO:0044106 44 0.051
regulation of cellular amine metabolic process GO:0033238 20 0.050
spermatogenesis GO:0007283 284 0.046
amine metabolic process GO:0009308 45 0.046
regulation of organelle organization GO:0033043 289 0.043
male gamete generation GO:0048232 285 0.039
gonad development GO:0008406 141 0.039
response to organonitrogen compound GO:0010243 246 0.039
male sex differentiation GO:0046661 109 0.038
cellular ketone metabolic process GO:0042180 84 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.035
purine ribonucleotide metabolic process GO:0009150 290 0.035
anatomical structure homeostasis GO:0060249 145 0.034
regulation of cellular ketone metabolic process GO:0010565 66 0.034
cellular nitrogen compound catabolic process GO:0044270 280 0.033
leukocyte differentiation GO:0002521 342 0.032
cellular response to hormone stimulus GO:0032870 150 0.032
germ cell development GO:0007281 185 0.031
Zebrafish
nucleotide metabolic process GO:0009117 332 0.031
purine containing compound metabolic process GO:0072521 311 0.031
regulation of cell cycle GO:0051726 281 0.031
positive regulation of protein modification process GO:0031401 299 0.030
mapk cascade GO:0000165 281 0.030
purine nucleotide metabolic process GO:0006163 302 0.030
heterocycle catabolic process GO:0046700 280 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
lymphocyte differentiation GO:0030098 242 0.029
nitrogen compound transport GO:0071705 271 0.029
positive regulation of nervous system development GO:0051962 221 0.028
positive regulation of cell development GO:0010720 237 0.028
spermatid development GO:0007286 108 0.028
spermatid differentiation GO:0048515 115 0.028
camera type eye development GO:0043010 266 0.028
meiotic nuclear division GO:0007126 115 0.028
dna metabolic process GO:0006259 303 0.028
Human
regulation of apoptotic signaling pathway GO:2001233 197 0.028
chromatin organization GO:0006325 206 0.027
cellular amino acid metabolic process GO:0006520 103 0.027
cellular response to dna damage stimulus GO:0006974 207 0.027
Human
regulation of hormone levels GO:0010817 211 0.027
oxidation reduction process GO:0055114 342 0.026
gland development GO:0048732 330 0.025
regulation of cellular amino acid metabolic process GO:0006521 5 0.024
synaptic transmission GO:0007268 329 0.024
regulation of secretion GO:0051046 274 0.024
organic cyclic compound catabolic process GO:1901361 295 0.024
urogenital system development GO:0001655 261 0.024
tissue homeostasis GO:0001894 115 0.023
carbohydrate metabolic process GO:0005975 230 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.023
organelle fission GO:0048285 170 0.023
regulation of transferase activity GO:0051338 263 0.023
intracellular receptor signaling pathway GO:0030522 74 0.023
regulation of system process GO:0044057 200 0.023
regulation of cytokine production GO:0001817 266 0.023
peptidyl amino acid modification GO:0018193 336 0.023
ribose phosphate metabolic process GO:0019693 291 0.022
g protein coupled receptor signaling pathway GO:0007186 243 0.022
innate immune response GO:0045087 157 0.022
apoptotic signaling pathway GO:0097190 306 0.022
myeloid cell differentiation GO:0030099 233 0.022
peptide transport GO:0015833 133 0.022
epithelial tube morphogenesis GO:0060562 303 0.022
sensory organ morphogenesis GO:0090596 242 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.022
activation of immune response GO:0002253 138 0.022
development of primary female sexual characteristics GO:0046545 73 0.022
positive regulation of apoptotic process GO:0043065 217 0.021
multicellular organismal homeostasis GO:0048871 164 0.021
cellular protein complex assembly GO:0043623 116 0.021
cellular macromolecule catabolic process GO:0044265 206 0.020
blood circulation GO:0008015 195 0.020
meiotic cell cycle GO:0051321 122 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
skin development GO:0043588 220 0.020
regulation of secretion by cell GO:1903530 249 0.020
cell type specific apoptotic process GO:0097285 268 0.020
peptide hormone secretion GO:0030072 109 0.019
anion transport GO:0006820 177 0.019
immune response activating signal transduction GO:0002757 116 0.019
development of primary male sexual characteristics GO:0046546 88 0.019
development of primary sexual characteristics GO:0045137 143 0.019
lateral inhibition GO:0046331 1 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
microtubule based process GO:0007017 236 0.019
hormone secretion GO:0046879 128 0.019
rhythmic process GO:0048511 174 0.019
regulation of defense response GO:0031347 233 0.019
response to organic cyclic compound GO:0014070 198 0.019
mitotic cell cycle GO:0000278 195 0.018
lipid biosynthetic process GO:0008610 179 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
cytokine production GO:0001816 319 0.018
cation homeostasis GO:0055080 212 0.018
organic anion transport GO:0015711 137 0.018
positive regulation of mapk cascade GO:0043410 170 0.018
positive regulation of organelle organization GO:0010638 128 0.018
muscle tissue development GO:0060537 308 0.018
embryonic organ morphogenesis GO:0048562 276 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
skeletal system development GO:0001501 356 0.018
regulation of myeloid cell differentiation GO:0045637 96 0.018
spermatogenesis exchange of chromosomal proteins GO:0035093 4 0.018
epithelial cell development GO:0002064 159 0.018
lung development GO:0030324 164 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
regulation of cell activation GO:0050865 289 0.017
regulation of neuron differentiation GO:0045664 281 0.017
cellular response to lipid GO:0071396 145 0.017
epithelial cell proliferation GO:0050673 174 0.017
epidermis development GO:0008544 187 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
chromatin modification GO:0016568 187 0.017
female sex differentiation GO:0046660 84 0.017
immune effector process GO:0002252 321 0.017
aromatic compound catabolic process GO:0019439 286 0.017
microtubule cytoskeleton organization GO:0000226 157 0.017
negative regulation of nervous system development GO:0051961 156 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
regulation of protein kinase activity GO:0045859 232 0.017
ear development GO:0043583 200 0.017
covalent chromatin modification GO:0016569 163 0.017
regulation of peptide secretion GO:0002791 77 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
cellular lipid metabolic process GO:0044255 323 0.017
regulation of body fluid levels GO:0050878 162 0.017
placenta development GO:0001890 140 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
nucleoside monophosphate metabolic process GO:0009123 85 0.016
histone modification GO:0016570 159 0.016
nucleoside metabolic process GO:0009116 246 0.016
regulation of mapk cascade GO:0043408 248 0.016
t cell activation GO:0042110 289 0.016
lipid localization GO:0010876 126 0.016
cytoplasmic transport GO:0016482 234 0.016
carbohydrate homeostasis GO:0033500 128 0.016
regulation of hormone secretion GO:0046883 88 0.016
immune response regulating signaling pathway GO:0002764 125 0.016
morphogenesis of a branching epithelium GO:0061138 193 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
cellular homeostasis GO:0019725 240 0.016
protein maturation GO:0051604 176 0.016
heart morphogenesis GO:0003007 178 0.016
response to acid chemical GO:0001101 111 0.015
extrinsic apoptotic signaling pathway GO:0097191 126 0.015
regulation of cellular response to stress GO:0080135 159 0.015
positive regulation of growth GO:0045927 104 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
macromolecule catabolic process GO:0009057 281 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
ovulation cycle GO:0042698 59 0.015
positive regulation of cell death GO:0010942 224 0.015
response to lipopolysaccharide GO:0032496 128 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
organic acid transport GO:0015849 101 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
cellular chemical homeostasis GO:0055082 215 0.015
regulation of cell motility GO:2000145 236 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
transmembrane transport GO:0055085 412 0.015
maintenance of location GO:0051235 89 0.015
regulation of cell cycle process GO:0010564 160 0.015
metal ion homeostasis GO:0055065 189 0.015
lipid transport GO:0006869 98 0.015
regulation of reproductive process GO:2000241 66 0.015
mrna metabolic process GO:0016071 84 0.015
nuclear division GO:0000280 158 0.015
nucleotide catabolic process GO:0009166 217 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.015
protein modification by small protein conjugation GO:0032446 187 0.014
multicellular organism growth GO:0035264 161 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
negative regulation of immune system process GO:0002683 209 0.014
carboxylic acid transport GO:0046942 100 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
protein catabolic process GO:0030163 221 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
regulation of homeostatic process GO:0032844 182 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
sensory perception GO:0007600 245 0.014
canonical wnt signaling pathway GO:0060070 130 0.014
cation transport GO:0006812 399 0.014
positive regulation of defense response GO:0031349 124 0.014
positive regulation of cellular component biogenesis GO:0044089 94 0.014
male gonad development GO:0008584 88 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
peptide secretion GO:0002790 114 0.014
response to growth factor GO:0070848 198 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
regulation of proteolysis GO:0030162 164 0.014
negative regulation of molecular function GO:0044092 258 0.014
glucose homeostasis GO:0042593 128 0.014
ras protein signal transduction GO:0007265 77 0.014
muscle cell differentiation GO:0042692 261 0.014
homeostasis of number of cells GO:0048872 210 0.013
amide transport GO:0042886 138 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
regionalization GO:0003002 337 0.013
meiosis i GO:0007127 60 0.013
regulation of intracellular transport GO:0032386 159 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
translation GO:0006412 93 0.013
intracellular protein transport GO:0006886 204 0.013
cellular response to lipopolysaccharide GO:0071222 77 0.013
insulin secretion GO:0030073 89 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
methylation GO:0032259 134 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
regulation of peptide hormone secretion GO:0090276 75 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
response to peptide GO:1901652 136 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
sequestering of calcium ion GO:0051208 18 0.013
positive regulation of cell activation GO:0050867 158 0.013
stem cell differentiation GO:0048863 268 0.013
neural tube development GO:0021915 160 0.013
kidney development GO:0001822 213 0.013
regulation of cell projection organization GO:0031344 206 0.013
cellular response to cytokine stimulus GO:0071345 189 0.012
axonogenesis GO:0007409 274 0.012
synapsis GO:0007129 34 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
regulation of protein localization GO:0032880 231 0.012
female gonad development GO:0008585 71 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
regulation of hydrolase activity GO:0051336 246 0.012
regulation of t cell activation GO:0050863 170 0.012
negative regulation of cell development GO:0010721 169 0.012
dna recombination GO:0006310 92 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
nucleoside phosphate biosynthetic process GO:1901293 79 0.012
membrane organization GO:0061024 245 0.012
steroid metabolic process GO:0008202 119 0.012
mitotic cell cycle process GO:1903047 159 0.012
skeletal muscle organ development GO:0060538 163 0.012
protein ubiquitination GO:0016567 171 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
tube formation GO:0035148 140 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
respiratory system development GO:0060541 190 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
epithelial tube formation GO:0072175 130 0.012
positive regulation of transferase activity GO:0051347 167 0.012
wnt signaling pathway involved in kidney development GO:0061289 2 0.012
inflammatory response GO:0006954 244 0.012
developmental maturation GO:0021700 193 0.012
circulatory system process GO:0003013 197 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
organophosphate catabolic process GO:0046434 232 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
activation of innate immune response GO:0002218 56 0.011
organelle assembly GO:0070925 177 0.011
lymphocyte proliferation GO:0046651 164 0.011
bone development GO:0060348 120 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
forebrain development GO:0030900 302 0.011
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
locomotory behavior GO:0007626 195 0.011
leukocyte mediated immunity GO:0002443 174 0.011
positive regulation of innate immune response GO:0045089 80 0.011
regulation of kinase activity GO:0043549 249 0.011
cell fate commitment GO:0045165 210 0.011
negative regulation of protein modification process GO:0031400 163 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
b cell differentiation GO:0030183 78 0.011
chemotaxis GO:0006935 247 0.011
activation of adenylate cyclase activity GO:0007190 4 0.011
blastocyst development GO:0001824 80 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
blood vessel morphogenesis GO:0048514 285 0.011
macromolecule methylation GO:0043414 120 0.011
regulation of inositol phosphate biosynthetic process GO:0010919 3 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
cellular ion homeostasis GO:0006873 165 0.011
response to peptide hormone GO:0043434 127 0.011
lung alveolus development GO:0048286 45 0.011
response to extracellular stimulus GO:0009991 127 0.011
cellular protein catabolic process GO:0044257 155 0.011
leukocyte proliferation GO:0070661 172 0.011
negative regulation of transferase activity GO:0051348 85 0.011
chromosome segregation GO:0007059 48 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
cell division GO:0051301 120 0.011
cellular alcohol biosynthetic process GO:0044108 3 0.011
regulation of innate immune response GO:0045088 91 0.011
tube closure GO:0060606 91 0.011
cellular response to gonadotropin stimulus GO:0071371 4 0.011
divalent inorganic cation transport GO:0072511 178 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
chromosome organization involved in meiosis GO:0070192 39 0.011
purine containing compound catabolic process GO:0072523 213 0.011
cell activation involved in immune response GO:0002263 126 0.010
protein secretion GO:0009306 111 0.010
production of molecular mediator of immune response GO:0002440 103 0.010
multi multicellular organism process GO:0044706 109 0.010
extracellular structure organization GO:0043062 148 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010
negative regulation of phosphorus metabolic process GO:0010563 184 0.010
neural tube formation GO:0001841 108 0.010
nucleotide biosynthetic process GO:0009165 78 0.010
response to oxidative stress GO:0006979 123 0.010
wnt signaling pathway GO:0016055 188 0.010
nucleoside phosphate catabolic process GO:1901292 222 0.010
regulation of organ morphogenesis GO:2000027 144 0.010
sulfur compound metabolic process GO:0006790 100 0.010
regulation of protein catabolic process GO:0042176 108 0.010
extracellular matrix organization GO:0030198 147 0.010
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010
positive regulation of neuron differentiation GO:0045666 141 0.010
alpha beta t cell activation GO:0046631 91 0.010
male meiosis GO:0007140 37 0.010
small molecule biosynthetic process GO:0044283 132 0.010
stem cell development GO:0048864 219 0.010
ribonucleoside triphosphate catabolic process GO:0009203 199 0.010
regulation of blood pressure GO:0008217 93 0.010
cation transmembrane transport GO:0098655 266 0.010
rna processing GO:0006396 105 0.010
cellular response to biotic stimulus GO:0071216 92 0.010

Fancl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.015
Human
disease of anatomical entity DOID:7 0 0.015
Human
hematopoietic system disease DOID:74 0 0.015
Human
nervous system disease DOID:863 0 0.012
central nervous system disease DOID:331 0 0.010