Mus musculus

38 known processes

Grm3

glutamate receptor, metabotropic 3

(Aliases: Gprc1c,0710001G23Rik,mGlu3,mGluR3)

Grm3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.180
synaptic transmission GO:0007268 329 0.170
Mouse Rat Fly
cation transmembrane transport GO:0098655 266 0.153
ion transmembrane transport GO:0034220 361 0.096
regulation of neuron differentiation GO:0045664 281 0.087
cation transport GO:0006812 399 0.077
cellular ketone metabolic process GO:0042180 84 0.063
regulation of secretion GO:0051046 274 0.059
metal ion homeostasis GO:0055065 189 0.058
inorganic ion transmembrane transport GO:0098660 234 0.057
positive regulation of nervous system development GO:0051962 221 0.055
positive regulation of transferase activity GO:0051347 167 0.052
Mouse
organophosphate catabolic process GO:0046434 232 0.052
purine containing compound metabolic process GO:0072521 311 0.051
positive regulation of cell development GO:0010720 237 0.051
regulation of system process GO:0044057 200 0.050
Mouse
ribose phosphate metabolic process GO:0019693 291 0.050
nitrogen compound transport GO:0071705 271 0.050
cellular lipid metabolic process GO:0044255 323 0.049
regulation of homeostatic process GO:0032844 182 0.048
action potential GO:0001508 78 0.047
cation homeostasis GO:0055080 212 0.047
ras protein signal transduction GO:0007265 77 0.047
locomotory behavior GO:0007626 195 0.046
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.046
small gtpase mediated signal transduction GO:0007264 97 0.046
anion transport GO:0006820 177 0.045
regulation of membrane potential GO:0042391 192 0.045
regulation of secretion by cell GO:1903530 249 0.042
regulation of cellular amine metabolic process GO:0033238 20 0.041
cellular homeostasis GO:0019725 240 0.041
ribonucleotide metabolic process GO:0009259 291 0.040
regulation of cellular amino acid metabolic process GO:0006521 5 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.040
purine nucleotide metabolic process GO:0006163 302 0.040
regulation of neuron projection development GO:0010975 169 0.040
circulatory system process GO:0003013 197 0.039
positive regulation of protein phosphorylation GO:0001934 242 0.038
Mouse
regulation of anatomical structure size GO:0090066 178 0.038
ribonucleotide catabolic process GO:0009261 208 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
negative regulation of phosphate metabolic process GO:0045936 184 0.037
organonitrogen compound catabolic process GO:1901565 264 0.037
telencephalon development GO:0021537 186 0.037
regulation of nucleoside metabolic process GO:0009118 130 0.037
inorganic cation transmembrane transport GO:0098662 207 0.037
camera type eye development GO:0043010 266 0.037
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.036
negative regulation of phosphorus metabolic process GO:0010563 184 0.036
compound eye development GO:0048749 1 0.035
forebrain development GO:0030900 302 0.035
neuronal action potential GO:0019228 54 0.035
cellular amino acid metabolic process GO:0006520 103 0.035
nucleotide metabolic process GO:0009117 332 0.035
positive regulation of neuron differentiation GO:0045666 141 0.034
regulation of cellular catabolic process GO:0031329 242 0.034
multicellular organismal signaling GO:0035637 91 0.034
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.034
cell adhesion GO:0007155 329 0.033
membrane organization GO:0061024 245 0.033
organic cyclic compound catabolic process GO:1901361 295 0.033
positive regulation of protein modification process GO:0031401 299 0.033
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.033
aromatic compound catabolic process GO:0019439 286 0.033
adult behavior GO:0030534 135 0.033
Mouse
negative regulation of cell development GO:0010721 169 0.033
heterocycle catabolic process GO:0046700 280 0.032
hormone secretion GO:0046879 128 0.032
regionalization GO:0003002 337 0.031
purine ribonucleotide catabolic process GO:0009154 208 0.031
response to organonitrogen compound GO:0010243 246 0.031
Mouse
embryonic organ morphogenesis GO:0048562 276 0.031
endocytosis GO:0006897 168 0.031
regulation of cell projection organization GO:0031344 206 0.031
protein maturation GO:0051604 176 0.030
ribonucleoside catabolic process GO:0042454 206 0.030
stem cell differentiation GO:0048863 268 0.029
mapk cascade GO:0000165 281 0.029
Mouse
axonogenesis GO:0007409 274 0.029
regulation of transferase activity GO:0051338 263 0.029
Mouse
organophosphate biosynthetic process GO:0090407 122 0.029
transmission of nerve impulse GO:0019226 76 0.029
Mouse
cognition GO:0050890 149 0.029
Mouse
cellular response to lipid GO:0071396 145 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
guanosine containing compound metabolic process GO:1901068 144 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
peptide secretion GO:0002790 114 0.028
purine containing compound catabolic process GO:0072523 213 0.028
organonitrogen compound biosynthetic process GO:1901566 192 0.028
regulation of blood circulation GO:1903522 93 0.028
nucleotide catabolic process GO:0009166 217 0.027
regulation of cellular component biogenesis GO:0044087 181 0.027
purine ribonucleotide metabolic process GO:0009150 290 0.027
cellular metal ion homeostasis GO:0006875 151 0.027
regulation of synaptic plasticity GO:0048167 87 0.027
Mouse
regulation of hydrolase activity GO:0051336 246 0.027
neuromuscular process GO:0050905 99 0.027
negative regulation of molecular function GO:0044092 258 0.026
ossification GO:0001503 216 0.026
g protein coupled receptor signaling pathway GO:0007186 243 0.026
regulation of ion transport GO:0043269 215 0.026
Mouse
peptidyl amino acid modification GO:0018193 336 0.025
regulation of purine nucleotide metabolic process GO:1900542 169 0.025
learning GO:0007612 98 0.025
Mouse
myeloid cell differentiation GO:0030099 233 0.025
cellular amine metabolic process GO:0044106 44 0.025
anion transmembrane transport GO:0098656 71 0.025
monocarboxylic acid metabolic process GO:0032787 191 0.025
amide transport GO:0042886 138 0.025
regulation of hormone levels GO:0010817 211 0.024
amine metabolic process GO:0009308 45 0.024
peptide transport GO:0015833 133 0.024
regulation of nucleotide metabolic process GO:0006140 169 0.024
rap protein signal transduction GO:0032486 3 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
glycosyl compound metabolic process GO:1901657 246 0.024
reactive nitrogen species metabolic process GO:2001057 0 0.024
regulation of gtp catabolic process GO:0033124 113 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.024
regulation of response to wounding GO:1903034 189 0.024
regulation of postsynaptic membrane potential GO:0060078 48 0.023
skeletal system development GO:0001501 356 0.023
learning or memory GO:0007611 148 0.023
Mouse
placenta development GO:0001890 140 0.023
peptide hormone secretion GO:0030072 109 0.023
gland development GO:0048732 330 0.023
regulation of protein kinase activity GO:0045859 232 0.023
Mouse
amino acid transport GO:0006865 61 0.023
regulation of neurotransmitter levels GO:0001505 87 0.022
Mouse
regulation of peptide secretion GO:0002791 77 0.022
purine nucleotide catabolic process GO:0006195 211 0.022
developmental maturation GO:0021700 193 0.022
regulation of purine nucleotide catabolic process GO:0033121 122 0.022
negative regulation of neuron differentiation GO:0045665 101 0.022
cellular ion homeostasis GO:0006873 165 0.022
regulation of protein serine threonine kinase activity GO:0071900 157 0.021
Mouse
sensory perception of mechanical stimulus GO:0050954 107 0.021
nucleoside metabolic process GO:0009116 246 0.021
neuron neuron synaptic transmission GO:0007270 69 0.021
Mouse Fly
blood circulation GO:0008015 195 0.021
cellular chemical homeostasis GO:0055082 215 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
ear development GO:0043583 200 0.021
lateral inhibition GO:0046331 1 0.020
peptidyl tyrosine phosphorylation GO:0018108 143 0.020
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
regulation of kinase activity GO:0043549 249 0.020
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
organic anion transport GO:0015711 137 0.020
regulation of body fluid levels GO:0050878 162 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
glial cell differentiation GO:0010001 131 0.019
carbohydrate metabolic process GO:0005975 230 0.019
rho protein signal transduction GO:0007266 32 0.019
immune effector process GO:0002252 321 0.019
regulation of transmembrane transport GO:0034762 128 0.019
Mouse
morphogenesis of a branching structure GO:0001763 203 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
calcium ion homeostasis GO:0055074 127 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
lipid transport GO:0006869 98 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
lipid localization GO:0010876 126 0.019
Worm
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.019
Mouse
regulation of establishment of protein localization GO:0070201 181 0.019
cellular carbohydrate metabolic process GO:0044262 119 0.019
protein processing GO:0016485 163 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
regulation of hormone secretion GO:0046883 88 0.018
neuroblast division in subventricular zone GO:0021849 2 0.018
gtp catabolic process GO:0006184 143 0.018
spermatogenesis GO:0007283 284 0.018
cell type specific apoptotic process GO:0097285 268 0.018
organelle localization GO:0051640 179 0.018
cell maturation GO:0048469 127 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
regulation of peptide transport GO:0090087 91 0.018
neuron migration GO:0001764 122 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
sensory perception GO:0007600 245 0.017
Mouse
maintenance of location GO:0051235 89 0.017
Worm
divalent inorganic cation homeostasis GO:0072507 138 0.017
activation of mapk activity GO:0000187 59 0.017
Mouse
fat cell differentiation GO:0045444 160 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
sensory organ morphogenesis GO:0090596 242 0.017
neuron death GO:0070997 154 0.017
multi multicellular organism process GO:0044706 109 0.017
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 3 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
Mouse
phospholipid metabolic process GO:0006644 87 0.017
apoptotic signaling pathway GO:0097190 306 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
oxidation reduction process GO:0055114 342 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
central nervous system neuron differentiation GO:0021953 162 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
guanosine containing compound catabolic process GO:1901069 144 0.017
dephosphorylation GO:0016311 129 0.017
nucleoside catabolic process GO:0009164 206 0.016
cardiac muscle contraction GO:0060048 32 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
positive regulation of mapk cascade GO:0043410 170 0.016
Mouse
positive regulation of kinase activity GO:0033674 155 0.016
Mouse
digestive tract development GO:0048565 190 0.016
negative regulation of neuron projection regeneration GO:0070571 3 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
muscle cell differentiation GO:0042692 261 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
regulation of cellular response to stress GO:0080135 159 0.016
regulation of organelle organization GO:0033043 289 0.016
g protein coupled glutamate receptor signaling pathway GO:0007216 3 0.016
organic acid transport GO:0015849 101 0.016
cytoplasmic transport GO:0016482 234 0.016
positive regulation of gtp catabolic process GO:0033126 85 0.016
single organism cell adhesion GO:0098602 156 0.016
sensory system development GO:0048880 3 0.016
male gamete generation GO:0048232 285 0.016
regulation of heart contraction GO:0008016 77 0.016
morphogenesis of a branching epithelium GO:0061138 193 0.015
cell growth GO:0016049 130 0.015
response to acid chemical GO:0001101 111 0.015
wnt signaling pathway GO:0016055 188 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
positive regulation of cell projection organization GO:0031346 95 0.015
regulation of cell adhesion GO:0030155 154 0.015
insulin secretion GO:0030073 89 0.015
regulation of nucleotide catabolic process GO:0030811 122 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
response to lipopolysaccharide GO:0032496 128 0.015
retina development in camera type eye GO:0060041 119 0.015
Mouse
protein secretion GO:0009306 111 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.015
regulation of proteolysis GO:0030162 164 0.015
regulation of cell growth GO:0001558 91 0.015
urogenital system development GO:0001655 261 0.015
morphogenesis of embryonic epithelium GO:0016331 159 0.015
regulation of protein localization GO:0032880 231 0.015
gliogenesis GO:0042063 141 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
neurotransmitter transport GO:0006836 76 0.014
Mouse
renal system development GO:0072001 225 0.014
epithelial cell development GO:0002064 159 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
regulation of protein transport GO:0051223 163 0.014
positive regulation of map kinase activity GO:0043406 84 0.014
Mouse
regulation of map kinase activity GO:0043405 120 0.014
Mouse
blood vessel morphogenesis GO:0048514 285 0.014
regulation of ras protein signal transduction GO:0046578 114 0.014
negative regulation of nervous system development GO:0051961 156 0.014
inorganic anion transport GO:0015698 43 0.014
positive regulation of gtpase activity GO:0043547 85 0.014
muscle system process GO:0003012 141 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
cell division GO:0051301 120 0.014
regulation of cellular component size GO:0032535 121 0.014
sodium ion transport GO:0006814 73 0.014
sensory perception of sound GO:0007605 97 0.014
single organismal cell cell adhesion GO:0016337 131 0.014
divalent metal ion transport GO:0070838 172 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.014
neuron projection guidance GO:0097485 141 0.014
divalent inorganic cation transport GO:0072511 178 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.014
metencephalon development GO:0022037 89 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.014
cytokine production GO:0001816 319 0.014
positive regulation of hydrolase activity GO:0051345 148 0.013
carbohydrate homeostasis GO:0033500 128 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
olfactory learning GO:0008355 2 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
regulation of systemic arterial blood pressure GO:0003073 61 0.013
protein localization to membrane GO:0072657 108 0.013
response to nutrient levels GO:0031667 109 0.013
intracellular protein transport GO:0006886 204 0.013
positive regulation of ion transport GO:0043270 65 0.013
positive regulation of secretion GO:0051047 130 0.013
wound healing GO:0042060 157 0.013
heart contraction GO:0060047 93 0.013
neuron apoptotic process GO:0051402 142 0.013
branching morphogenesis of an epithelial tube GO:0048754 159 0.013
skin development GO:0043588 220 0.013
gtp metabolic process GO:0046039 144 0.013
response to radiation GO:0009314 165 0.013
regulation of ossification GO:0030278 112 0.013
receptor mediated endocytosis GO:0006898 51 0.013
ensheathment of neurons GO:0007272 76 0.013
positive regulation of nucleotide catabolic process GO:0030813 88 0.013
striated muscle tissue development GO:0014706 293 0.013
heart process GO:0003015 94 0.013
positive regulation of cell death GO:0010942 224 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
cellular calcium ion homeostasis GO:0006874 119 0.013
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.013
response to organic cyclic compound GO:0014070 198 0.013
Mouse
ribose phosphate biosynthetic process GO:0046390 59 0.013
forebrain generation of neurons GO:0021872 63 0.013
regulation of carbohydrate metabolic process GO:0006109 75 0.012
homeostasis of number of cells GO:0048872 210 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
camp biosynthetic process GO:0006171 31 0.012
central nervous system neuron development GO:0021954 67 0.012
fatty acid metabolic process GO:0006631 121 0.012
inclusion body assembly GO:0070841 3 0.012
protein catabolic process GO:0030163 221 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
cochlea development GO:0090102 35 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
membrane depolarization GO:0051899 64 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.012
generation of precursor metabolites and energy GO:0006091 103 0.012
positive regulation of nucleoside metabolic process GO:0045979 91 0.012
myelination GO:0042552 74 0.012
exocytosis GO:0006887 121 0.012
neuromuscular process controlling balance GO:0050885 59 0.012
negative regulation of cell projection organization GO:0031345 56 0.012
regulation of cell motility GO:2000145 236 0.012
muscle tissue development GO:0060537 308 0.012
macromolecule catabolic process GO:0009057 281 0.012
regulation of cytokine production GO:0001817 266 0.012
epithelial cell proliferation GO:0050673 174 0.012
circadian rhythm GO:0007623 114 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
Mouse
regulation of blood vessel size GO:0050880 56 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
chemotaxis GO:0006935 247 0.012
neural precursor cell proliferation GO:0061351 121 0.012
germ cell development GO:0007281 185 0.012
habituation GO:0046959 3 0.011
cellular protein catabolic process GO:0044257 155 0.011
multicellular organismal response to stress GO:0033555 62 0.011
Mouse
adult locomotory behavior GO:0008344 91 0.011
Mouse
regulation of cell migration GO:0030334 219 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
regulation of neuronal synaptic plasticity GO:0048168 30 0.011
Mouse
rac protein signal transduction GO:0016601 13 0.011
regulation of gliogenesis GO:0014013 50 0.011
inter male aggressive behavior GO:0002121 3 0.011
calcium ion transmembrane transport GO:0070588 85 0.011
behavioral fear response GO:0001662 28 0.011
Mouse
cell fate commitment GO:0045165 210 0.011
gonad development GO:0008406 141 0.011
conditioned taste aversion GO:0001661 4 0.011
Mouse
cellular response to organic cyclic compound GO:0071407 87 0.011
regulation of ion transmembrane transporter activity GO:0032412 54 0.011
glycerolipid metabolic process GO:0046486 122 0.011
lateral line system development GO:0048925 1 0.011
regulation of cell cycle GO:0051726 281 0.011
spermatid development GO:0007286 108 0.011
cyclic purine nucleotide metabolic process GO:0052652 43 0.011
developmental cell growth GO:0048588 84 0.011
single fertilization GO:0007338 82 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
cerebellum development GO:0021549 77 0.011
notochord cell development GO:0060035 1 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
lymphocyte differentiation GO:0030098 242 0.011
regulation of protein processing GO:0070613 96 0.011
embryonic placenta development GO:0001892 98 0.011
thermosensory behavior GO:0040040 1 0.011
heart morphogenesis GO:0003007 178 0.011
regulation of ion homeostasis GO:2000021 64 0.011
adult walking behavior GO:0007628 41 0.011
purine nucleotide biosynthetic process GO:0006164 65 0.011
regulation of glial cell differentiation GO:0045685 41 0.011
response to amphetamine GO:0001975 16 0.011
regulation of renin secretion into blood stream GO:1900133 4 0.011
regulation of protein maturation GO:1903317 96 0.011
response to light stimulus GO:0009416 135 0.011
ear morphogenesis GO:0042471 118 0.011
gastrulation GO:0007369 116 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
stem cell development GO:0048864 219 0.011
leukocyte differentiation GO:0002521 342 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
regulation of blood pressure GO:0008217 93 0.011
regulation of peptide hormone secretion GO:0090276 75 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
cyclic nucleotide metabolic process GO:0009187 59 0.010
glycoprotein metabolic process GO:0009100 116 0.010
cytosolic calcium ion homeostasis GO:0051480 70 0.010
transition metal ion homeostasis GO:0055076 54 0.010
protein ubiquitination GO:0016567 171 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
calcium ion transport GO:0006816 159 0.010
cardiac ventricle development GO:0003231 83 0.010
negative regulation of bone trabecula formation GO:1900155 1 0.010
appendage morphogenesis GO:0035107 149 0.010
regulation of astrocyte differentiation GO:0048710 20 0.010
canonical wnt signaling pathway GO:0060070 130 0.010
regulation of apoptotic signaling pathway GO:2001233 197 0.010
lung development GO:0030324 164 0.010
dendrite development GO:0016358 115 0.010
protein polymerization GO:0051258 57 0.010
regulation of ras gtpase activity GO:0032318 88 0.010
microtubule based process GO:0007017 236 0.010
ribonucleotide biosynthetic process GO:0009260 59 0.010
oocyte construction GO:0007308 2 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.010
inflammatory response GO:0006954 244 0.010
cellular macromolecule catabolic process GO:0044265 206 0.010
protein localization to organelle GO:0033365 185 0.010

Grm3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
central nervous system disease DOID:331 0 0.013
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010