Mus musculus

0 known processes

H2-M1

histocompatibility 2, M region locus 1

(Aliases: H-2M1,H2-Qa-Mb1,Mb1)

H2-M1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.086
oxidation reduction process GO:0055114 342 0.063
regulation of cellular amino acid metabolic process GO:0006521 5 0.060
transmembrane transport GO:0055085 412 0.056
ion transmembrane transport GO:0034220 361 0.052
lymphocyte mediated immunity GO:0002449 139 0.050
Mouse
organic anion transport GO:0015711 137 0.050
immune effector process GO:0002252 321 0.050
Mouse
response to organic cyclic compound GO:0014070 198 0.049
regulation of cellular ketone metabolic process GO:0010565 66 0.048
response to peptide hormone GO:0043434 127 0.044
regulation of cellular amine metabolic process GO:0033238 20 0.043
cellular amino acid metabolic process GO:0006520 103 0.043
cell type specific apoptotic process GO:0097285 268 0.042
regulation of secretion GO:0051046 274 0.040
cation transport GO:0006812 399 0.040
cellular amine metabolic process GO:0044106 44 0.040
cellular response to lipid GO:0071396 145 0.039
male gamete generation GO:0048232 285 0.039
response to organonitrogen compound GO:0010243 246 0.038
anion transport GO:0006820 177 0.037
metal ion homeostasis GO:0055065 189 0.037
spermatogenesis GO:0007283 284 0.036
gland development GO:0048732 330 0.035
cation homeostasis GO:0055080 212 0.034
cellular lipid metabolic process GO:0044255 323 0.033
g protein coupled receptor signaling pathway GO:0007186 243 0.033
cation transmembrane transport GO:0098655 266 0.032
response to lipopolysaccharide GO:0032496 128 0.032
regulation of cell motility GO:2000145 236 0.032
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
cell adhesion GO:0007155 329 0.030
apoptotic signaling pathway GO:0097190 306 0.030
response to peptide GO:1901652 136 0.030
renal system process GO:0003014 48 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
positive regulation of protein modification process GO:0031401 299 0.029
negative regulation of cellular protein metabolic process GO:0032269 247 0.029
positive regulation of protein phosphorylation GO:0001934 242 0.028
cellular homeostasis GO:0019725 240 0.028
positive regulation of cell development GO:0010720 237 0.028
multicellular organismal signaling GO:0035637 91 0.027
inflammatory response GO:0006954 244 0.027
cellular response to cytokine stimulus GO:0071345 189 0.027
nitrogen compound transport GO:0071705 271 0.027
nucleotide metabolic process GO:0009117 332 0.027
response to molecule of bacterial origin GO:0002237 143 0.027
regulation of cytokine production GO:0001817 266 0.027
Mouse
divalent metal ion transport GO:0070838 172 0.026
positive regulation of cytokine production GO:0001819 174 0.026
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.026
myotube differentiation GO:0014902 105 0.026
multicellular organismal homeostasis GO:0048871 164 0.026
reactive nitrogen species metabolic process GO:2001057 0 0.026
regulation of hormone levels GO:0010817 211 0.025
regulation of cellular response to stress GO:0080135 159 0.025
ear development GO:0043583 200 0.025
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.025
organic acid transport GO:0015849 101 0.025
regulation of membrane potential GO:0042391 192 0.025
regulation of organelle organization GO:0033043 289 0.025
response to inorganic substance GO:0010035 96 0.025
cellular response to organonitrogen compound GO:0071417 145 0.025
synaptic transmission GO:0007268 329 0.025
inorganic cation transmembrane transport GO:0098662 207 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
regulation of mapk cascade GO:0043408 248 0.024
carboxylic acid transport GO:0046942 100 0.024
regulation of cell projection organization GO:0031344 206 0.024
cytoplasmic transport GO:0016482 234 0.024
kidney development GO:0001822 213 0.023
carbohydrate metabolic process GO:0005975 230 0.023
regulation of system process GO:0044057 200 0.023
protein processing GO:0016485 163 0.023
response to extracellular stimulus GO:0009991 127 0.023
mapk cascade GO:0000165 281 0.023
negative regulation of immune system process GO:0002683 209 0.023
skeletal muscle organ development GO:0060538 163 0.023
dna metabolic process GO:0006259 303 0.023
cellular response to hormone stimulus GO:0032870 150 0.022
maintenance of location GO:0051235 89 0.022
cellular response to peptide GO:1901653 92 0.022
monocarboxylic acid metabolic process GO:0032787 191 0.022
fertilization GO:0009566 127 0.022
negative regulation of protein modification process GO:0031400 163 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.022
cytokine production GO:0001816 319 0.022
Mouse
lipid transport GO:0006869 98 0.021
purine containing compound metabolic process GO:0072521 311 0.021
meiotic nuclear division GO:0007126 115 0.021
muscle tissue development GO:0060537 308 0.021
adaptive immune response GO:0002250 155 0.021
Mouse
cellular response to organic cyclic compound GO:0071407 87 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
response to acid chemical GO:0001101 111 0.021
camera type eye development GO:0043010 266 0.021
macromolecule catabolic process GO:0009057 281 0.021
regulation of body fluid levels GO:0050878 162 0.021
negative regulation of molecular function GO:0044092 258 0.021
t cell activation GO:0042110 289 0.021
organic hydroxy compound metabolic process GO:1901615 203 0.021
regulation of neuron differentiation GO:0045664 281 0.020
antigen processing and presentation GO:0019882 47 0.020
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.020
amine metabolic process GO:0009308 45 0.020
urogenital system development GO:0001655 261 0.020
small gtpase mediated signal transduction GO:0007264 97 0.020
regulation of transmembrane transport GO:0034762 128 0.020
neuron death GO:0070997 154 0.020
action potential GO:0001508 78 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
lipid localization GO:0010876 126 0.020
transmission of nerve impulse GO:0019226 76 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
production of molecular mediator of immune response GO:0002440 103 0.020
regulation of protein transport GO:0051223 163 0.019
regulation of secretion by cell GO:1903530 249 0.019
protein maturation GO:0051604 176 0.019
sensory perception GO:0007600 245 0.019
striated muscle tissue development GO:0014706 293 0.019
regulation of defense response GO:0031347 233 0.019
heterocycle catabolic process GO:0046700 280 0.019
response to growth factor GO:0070848 198 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
nuclear division GO:0000280 158 0.019
regulation of intracellular transport GO:0032386 159 0.019
protein kinase b signaling GO:0043491 74 0.019
small molecule biosynthetic process GO:0044283 132 0.019
regulation of ion transport GO:0043269 215 0.019
positive regulation of nervous system development GO:0051962 221 0.019
regulation of cell cycle process GO:0010564 160 0.019
angiogenesis GO:0001525 201 0.018
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.018
Mouse
organophosphate biosynthetic process GO:0090407 122 0.018
cellular chemical homeostasis GO:0055082 215 0.018
germ cell development GO:0007281 185 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
exocytosis GO:0006887 121 0.018
muscle fiber development GO:0048747 76 0.018
regulation of kinase activity GO:0043549 249 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
calcium ion homeostasis GO:0055074 127 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
regulation of ion transmembrane transport GO:0034765 119 0.018
divalent inorganic cation transport GO:0072511 178 0.018
regulation of leukocyte mediated immunity GO:0002703 104 0.018
Mouse
cellular response to biotic stimulus GO:0071216 92 0.018
retina development in camera type eye GO:0060041 119 0.017
cell activation involved in immune response GO:0002263 126 0.017
protein localization to nucleus GO:0034504 121 0.017
wound healing GO:0042060 157 0.017
branching morphogenesis of an epithelial tube GO:0048754 159 0.017
response to insulin GO:0032868 100 0.017
fat cell differentiation GO:0045444 160 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.017
leukocyte proliferation GO:0070661 172 0.017
organelle fission GO:0048285 170 0.017
regulation of response to wounding GO:1903034 189 0.017
positive regulation of kinase activity GO:0033674 155 0.017
protein localization to organelle GO:0033365 185 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
positive regulation of secretion GO:0051047 130 0.017
cellular response to peptide hormone stimulus GO:0071375 92 0.017
calcium ion transport GO:0006816 159 0.017
regulation of cell migration GO:0030334 219 0.017
leukocyte differentiation GO:0002521 342 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
regulation of lymphocyte mediated immunity GO:0002706 84 0.016
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.016
fatty acid metabolic process GO:0006631 121 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
protein secretion GO:0009306 111 0.016
morphogenesis of a branching epithelium GO:0061138 193 0.016
regulation of vasculature development GO:1901342 88 0.016
cellular response to molecule of bacterial origin GO:0071219 83 0.016
positive regulation of cell death GO:0010942 224 0.016
leukocyte mediated immunity GO:0002443 174 0.016
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.016
Mouse
peptidyl amino acid modification GO:0018193 336 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
interferon gamma production GO:0032609 67 0.016
Mouse
lymphocyte differentiation GO:0030098 242 0.016
cognition GO:0050890 149 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
membrane organization GO:0061024 245 0.016
cell substrate adhesion GO:0031589 130 0.016
developmental growth involved in morphogenesis GO:0060560 138 0.016
morphogenesis of a branching structure GO:0001763 203 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
olfactory learning GO:0008355 2 0.016
response to steroid hormone GO:0048545 56 0.016
spermatid development GO:0007286 108 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.015
intracellular protein transport GO:0006886 204 0.015
cell growth GO:0016049 130 0.015
organelle localization GO:0051640 179 0.015
regulation of blood pressure GO:0008217 93 0.015
nucleoside phosphate metabolic process GO:0006753 338 0.015
neuronal action potential GO:0019228 54 0.015
spermatid differentiation GO:0048515 115 0.015
positive regulation of cell motility GO:2000147 116 0.015
anatomical structure homeostasis GO:0060249 145 0.015
negative regulation of endothelial cell migration GO:0010596 4 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
regulation of protein kinase activity GO:0045859 232 0.015
nucleoside metabolic process GO:0009116 246 0.015
regulation of protein localization GO:0032880 231 0.015
cellular ion homeostasis GO:0006873 165 0.015
lipid biosynthetic process GO:0008610 179 0.015
aromatic compound catabolic process GO:0019439 286 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
forebrain development GO:0030900 302 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
skeletal muscle fiber development GO:0048741 58 0.015
generation of precursor metabolites and energy GO:0006091 103 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
sensory organ morphogenesis GO:0090596 242 0.014
regulation of production of molecular mediator of immune response GO:0002700 65 0.014
meiotic cell cycle process GO:1903046 77 0.014
cytosolic calcium ion homeostasis GO:0051480 70 0.014
regulation of chemotaxis GO:0050920 53 0.014
response to testosterone GO:0033574 3 0.014
multi multicellular organism process GO:0044706 109 0.014
glycoprotein metabolic process GO:0009100 116 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
lipid catabolic process GO:0016042 69 0.014
regulation of angiogenesis GO:0045765 81 0.014
vesicle localization GO:0051648 86 0.014
positive regulation of immune effector process GO:0002699 107 0.014
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.014
homeostasis of number of cells GO:0048872 210 0.014
regulation of cell substrate adhesion GO:0010810 73 0.014
b cell mediated immunity GO:0019724 71 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.014
regulation of lymphocyte differentiation GO:0045619 107 0.014
amide transport GO:0042886 138 0.014
muscle cell development GO:0055001 133 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
wnt signaling pathway GO:0016055 188 0.014
regulation of homeostatic process GO:0032844 182 0.013
positive regulation of cell projection organization GO:0031346 95 0.013
positive regulation of behavior GO:0048520 40 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
muscle cell differentiation GO:0042692 261 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
myeloid cell differentiation GO:0030099 233 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
microtubule based process GO:0007017 236 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
regulation of t cell activation GO:0050863 170 0.013
learning or memory GO:0007611 148 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
cellular response to lipopolysaccharide GO:0071222 77 0.013
b cell activation GO:0042113 161 0.013
central nervous system neuron differentiation GO:0021953 162 0.013
regulation of adaptive immune response GO:0002819 90 0.013
Mouse
sequestering of metal ion GO:0051238 19 0.013
regulation of cell cycle GO:0051726 281 0.013
sodium ion transport GO:0006814 73 0.013
cellular calcium ion homeostasis GO:0006874 119 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
cellular response to acid chemical GO:0071229 68 0.013
protein catabolic process GO:0030163 221 0.013
regulation of neuron death GO:1901214 134 0.013
nucleoside catabolic process GO:0009164 206 0.013
positive regulation of protein transport GO:0051222 93 0.013
hormone metabolic process GO:0042445 86 0.013
axonogenesis GO:0007409 274 0.013
circulatory system process GO:0003013 197 0.012
innate immune response GO:0045087 157 0.012
energy derivation by oxidation of organic compounds GO:0015980 77 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
defense response to bacterium GO:0042742 119 0.012
regulation of cell activation GO:0050865 289 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
protein ubiquitination GO:0016567 171 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
positive regulation of cell migration GO:0030335 109 0.012
regulation of intracellular protein transport GO:0033157 82 0.012
dephosphorylation GO:0016311 129 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
positive regulation of organelle organization GO:0010638 128 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
single fertilization GO:0007338 82 0.012
alcohol metabolic process GO:0006066 116 0.012
epithelium migration GO:0090132 63 0.012
immunoglobulin mediated immune response GO:0016064 69 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
negative regulation of response to wounding GO:1903035 77 0.012
regulation of protein kinase b signaling GO:0051896 56 0.012
regulation of cell adhesion GO:0030155 154 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
glycerolipid metabolic process GO:0046486 122 0.012
cell cell recognition GO:0009988 44 0.012
regulation of carbohydrate metabolic process GO:0006109 75 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
response to nutrient levels GO:0031667 109 0.012
neuron apoptotic process GO:0051402 142 0.012
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.012
myotube cell development GO:0014904 60 0.012
negative regulation of cell migration GO:0030336 59 0.012
leukocyte mediated cytotoxicity GO:0001909 62 0.012
Mouse
monocarboxylic acid transport GO:0015718 44 0.012
cardiac muscle tissue development GO:0048738 130 0.012
regulation of cellular component size GO:0032535 121 0.011
endomembrane system organization GO:0010256 147 0.011
regulation of skeletal muscle fiber development GO:0048742 36 0.011
positive regulation of transferase activity GO:0051347 167 0.011
mitotic cell cycle GO:0000278 195 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
t cell differentiation GO:0030217 174 0.011
negative regulation of homeostatic process GO:0032845 71 0.011
nuclear import GO:0051170 95 0.011
positive regulation of angiogenesis GO:0045766 46 0.011
monosaccharide metabolic process GO:0005996 106 0.011
regulation of hormone secretion GO:0046883 88 0.011
response to alcohol GO:0097305 48 0.011
striated muscle contraction GO:0006941 45 0.011
blood circulation GO:0008015 195 0.011
glucose homeostasis GO:0042593 128 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
response to transforming growth factor beta GO:0071559 88 0.011
small molecule catabolic process GO:0044282 71 0.011
positive regulation of vasoconstriction GO:0045907 4 0.011
blood vessel morphogenesis GO:0048514 285 0.011
protein targeting GO:0006605 143 0.011
regulation of myotube differentiation GO:0010830 62 0.011
antigen processing and presentation of peptide antigen GO:0048002 29 0.011
Mouse
nuclear transport GO:0051169 139 0.011
regulation of t helper 2 cell cytokine production GO:2000551 3 0.011
regulation of protein secretion GO:0050708 82 0.011
positive regulation of chemotaxis GO:0050921 38 0.011
ameboidal type cell migration GO:0001667 128 0.011
regulation of interferon gamma production GO:0032649 57 0.011
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
regulation of cell division GO:0051302 76 0.011
carbohydrate homeostasis GO:0033500 128 0.011
cellular response to insulin stimulus GO:0032869 78 0.011
defense response to other organism GO:0098542 197 0.011
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
meiotic cell cycle GO:0051321 122 0.011
regulation of hydrolase activity GO:0051336 246 0.011
chemotaxis GO:0006935 247 0.011
gliogenesis GO:0042063 141 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
heart process GO:0003015 94 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
cell junction organization GO:0034330 77 0.011
mitochondrion organization GO:0007005 134 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
regulation of muscle tissue development GO:1901861 97 0.011
establishment of organelle localization GO:0051656 122 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
epithelial cell development GO:0002064 159 0.011
rna processing GO:0006396 105 0.011
rho protein signal transduction GO:0007266 32 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
positive regulation of cell cycle GO:0045787 92 0.011
positive regulation of leukocyte mediated immunity GO:0002705 70 0.011
Mouse
regulation of anatomical structure size GO:0090066 178 0.010
positive regulation of protein secretion GO:0050714 52 0.010
fat soluble vitamin biosynthetic process GO:0042362 4 0.010
striated muscle cell development GO:0055002 125 0.010
cellular protein complex assembly GO:0043623 116 0.010
muscle contraction GO:0006936 101 0.010
anion transmembrane transport GO:0098656 71 0.010
regulation of proteolysis GO:0030162 164 0.010
blood coagulation GO:0007596 76 0.010
negative regulation of organelle organization GO:0010639 90 0.010
potassium ion transport GO:0006813 52 0.010
positive regulation of ion transport GO:0043270 65 0.010
hormone secretion GO:0046879 128 0.010
immunoglobulin production GO:0002377 73 0.010
development of primary sexual characteristics GO:0045137 143 0.010
protein import GO:0017038 101 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010

H2-M1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.023
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
central nervous system disease DOID:331 0 0.019
neurodegenerative disease DOID:1289 0 0.016
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.013