Mus musculus

64 known processes

Casp7

caspase 7

(Aliases: caspase-7,mCASP-7,ICE-IAP3,AI314680,CMH-1,Mch3)

Casp7 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of necroptotic process GO:0060546 9 0.228
Mouse
positive regulation of endopeptidase activity GO:0010950 43 0.200
Mouse
regulation of endopeptidase activity GO:0052548 89 0.172
Mouse
activation of cysteine type endopeptidase activity GO:0097202 27 0.171
Mouse
epidermis development GO:0008544 187 0.169
Mouse
positive regulation of proteolysis GO:0045862 85 0.167
Mouse
regulation of hydrolase activity GO:0051336 246 0.157
Mouse
regulation of cytokine production GO:0001817 266 0.156
Mouse
necroptotic process GO:0070266 21 0.154
Mouse
glial cell apoptotic process GO:0034349 3 0.153
Mouse
positive regulation of peptidase activity GO:0010952 49 0.147
Mouse
regulation of cell activation GO:0050865 289 0.145
Mouse
apoptotic signaling pathway GO:0097190 306 0.136
cell fate commitment GO:0045165 210 0.131
Mouse
regulation of cell cycle GO:0051726 281 0.130
Mouse
regulation of peptidase activity GO:0052547 96 0.126
Mouse
cell type specific apoptotic process GO:0097285 268 0.125
t cell activation GO:0042110 289 0.124
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.114
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.113
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.101
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 95 0.095
Mouse
negative regulation of molecular function GO:0044092 258 0.091
Mouse
cellular amino acid metabolic process GO:0006520 103 0.091
regulation of necroptotic process GO:0060544 10 0.090
Mouse
positive regulation of cell death GO:0010942 224 0.084
release of cytochrome c from mitochondria GO:0001836 23 0.084
b cell activation GO:0042113 161 0.084
Mouse
response to molecule of bacterial origin GO:0002237 143 0.082
Mouse
regulation of lymphocyte activation GO:0051249 240 0.082
Mouse
inflammatory response GO:0006954 244 0.081
Mouse
negative regulation of immune system process GO:0002683 209 0.079
Mouse
macromolecule catabolic process GO:0009057 281 0.078
Mouse
leukocyte homeostasis GO:0001776 79 0.077
Mouse
protein catabolic process GO:0030163 221 0.076
zymogen activation GO:0031638 41 0.076
Mouse
skin development GO:0043588 220 0.074
Mouse
aromatic compound catabolic process GO:0019439 286 0.074
Mouse
keratinocyte differentiation GO:0030216 48 0.073
Mouse
regulation of interleukin 1 alpha production GO:0032650 4 0.072
Mouse
regulation of proteolysis GO:0030162 164 0.069
Mouse
positive regulation of apoptotic process GO:0043065 217 0.068
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.068
Mouse
cytokine production GO:0001816 319 0.068
Mouse
protein maturation GO:0051604 176 0.067
apoptotic mitochondrial changes GO:0008637 48 0.067
negative regulation of kinase activity GO:0033673 81 0.067
Mouse
positive regulation of programmed cell death GO:0043068 218 0.067
t cell proliferation GO:0042098 120 0.066
Mouse
innate immune response GO:0045087 157 0.066
regulation of t cell activation GO:0050863 170 0.065
Mouse
necrotic cell death GO:0070265 30 0.065
Mouse
regulation of secretion by cell GO:1903530 249 0.064
Mouse
immune response activating signal transduction GO:0002757 116 0.064
leukocyte differentiation GO:0002521 342 0.063
Mouse
negative regulation of cell activation GO:0050866 111 0.061
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.060
Mouse
cellular amine metabolic process GO:0044106 44 0.060
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.059
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.059
Mouse
t cell homeostasis GO:0043029 35 0.058
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.058
Mouse
negative regulation of phosphorylation GO:0042326 166 0.058
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.057
Mouse
programmed necrotic cell death GO:0097300 28 0.056
Mouse
regulation of leukocyte apoptotic process GO:2000106 56 0.056
Mouse
response to lipopolysaccharide GO:0032496 128 0.056
Mouse
carbohydrate metabolic process GO:0005975 230 0.056
response to endoplasmic reticulum stress GO:0034976 53 0.056
Mouse
nucleotide metabolic process GO:0009117 332 0.055
negative regulation of cell proliferation GO:0008285 296 0.054
Mouse
leukocyte proliferation GO:0070661 172 0.054
Mouse
regulation of t cell proliferation GO:0042129 92 0.053
Mouse
neural tube development GO:0021915 160 0.052
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.052
Mouse
er nucleus signaling pathway GO:0006984 27 0.051
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.051
heterocycle catabolic process GO:0046700 280 0.051
Mouse
cellular response to dna damage stimulus GO:0006974 207 0.050
Mouse
dna metabolic process GO:0006259 303 0.050
Mouse
lymphocyte homeostasis GO:0002260 64 0.050
Mouse
regulation of transferase activity GO:0051338 263 0.049
Mouse
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.049
Mouse
embryonic epithelial tube formation GO:0001838 130 0.049
Mouse
positive regulation of innate immune response GO:0045089 80 0.048
cellular ketone metabolic process GO:0042180 84 0.048
regulation of membrane potential GO:0042391 192 0.047
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.047
morphogenesis of embryonic epithelium GO:0016331 159 0.047
Mouse
intrinsic apoptotic signaling pathway GO:0097193 132 0.046
Mouse
epithelial tube morphogenesis GO:0060562 303 0.045
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.045
negative regulation of transferase activity GO:0051348 85 0.045
Mouse
membrane organization GO:0061024 245 0.045
peptidyl amino acid modification GO:0018193 336 0.045
regulation of protein localization GO:0032880 231 0.045
Mouse
glycosyl compound metabolic process GO:1901657 246 0.045
cell adhesion GO:0007155 329 0.044
regulation of execution phase of apoptosis GO:1900117 9 0.044
Mouse
myeloid cell differentiation GO:0030099 233 0.044
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.044
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.043
i kappab kinase nf kappab signaling GO:0007249 85 0.043
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.043
regulation of protein transport GO:0051223 163 0.042
Mouse
regulation of defense response GO:0031347 233 0.041
Mouse
mitochondrion organization GO:0007005 134 0.041
b cell proliferation GO:0042100 53 0.040
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.040
response to organonitrogen compound GO:0010243 246 0.039
Mouse
cellular response to lipid GO:0071396 145 0.038
Mouse
homeostasis of number of cells GO:0048872 210 0.038
Mouse
germ cell development GO:0007281 185 0.037
regulation of kinase activity GO:0043549 249 0.037
Mouse
purine nucleoside metabolic process GO:0042278 241 0.037
oxidation reduction process GO:0055114 342 0.037
cytoplasmic transport GO:0016482 234 0.037
regulation of apoptotic signaling pathway GO:2001233 197 0.037
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.036
response to organic cyclic compound GO:0014070 198 0.036
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.036
endocytosis GO:0006897 168 0.036
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.036
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.036
membrane depolarization GO:0051899 64 0.036
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.035
Mouse
regulation of protein complex assembly GO:0043254 83 0.035
nitrogen compound transport GO:0071705 271 0.035
myeloid cell homeostasis GO:0002262 114 0.035
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.034
Mouse
negative regulation of t cell activation GO:0050868 65 0.034
Mouse
ribose phosphate metabolic process GO:0019693 291 0.034
interspecies interaction between organisms GO:0044419 83 0.034
regulation of secretion GO:0051046 274 0.034
Mouse
immune response regulating signaling pathway GO:0002764 125 0.034
nucleotide catabolic process GO:0009166 217 0.033
defense response to bacterium GO:0042742 119 0.033
carbohydrate derivative catabolic process GO:1901136 231 0.033
positive regulation of cellular amine metabolic process GO:0033240 5 0.033
epithelial tube formation GO:0072175 130 0.033
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.033
Mouse
leukocyte apoptotic process GO:0071887 71 0.032
Mouse
toxin transport GO:1901998 38 0.032
Mouse
cellular response to steroid hormone stimulus GO:0071383 33 0.032
Mouse
sensory perception GO:0007600 245 0.032
Mouse
macrophage differentiation GO:0030225 20 0.032
Mouse
cation transport GO:0006812 399 0.032
cellular response to lipopolysaccharide GO:0071222 77 0.032
purine ribonucleoside catabolic process GO:0046130 205 0.032
organophosphate catabolic process GO:0046434 232 0.031
regulation of leukocyte proliferation GO:0070663 121 0.031
Mouse
membrane hyperpolarization GO:0060081 21 0.031
Mouse
cellular homeostasis GO:0019725 240 0.031
purine nucleoside catabolic process GO:0006152 205 0.031
regulation of response to wounding GO:1903034 189 0.031
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.031
Mouse
negative regulation of protein modification process GO:0031400 163 0.031
Mouse
cellularization GO:0007349 1 0.031
monosaccharide metabolic process GO:0005996 106 0.030
sequestering of metal ion GO:0051238 19 0.030
activation of immune response GO:0002253 138 0.030
regulation of lymphocyte apoptotic process GO:0070228 41 0.030
Mouse
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.030
Mouse
ribonucleotide metabolic process GO:0009259 291 0.030
response to topologically incorrect protein GO:0035966 25 0.030
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.030
Mouse
cellular lipid metabolic process GO:0044255 323 0.029
muscle cell differentiation GO:0042692 261 0.029
negative regulation of b cell activation GO:0050869 27 0.029
Mouse
regulation of intracellular transport GO:0032386 159 0.029
regulation of anatomical structure size GO:0090066 178 0.029
regulation of necrotic cell death GO:0010939 13 0.029
Mouse
leukocyte mediated immunity GO:0002443 174 0.029
protein processing GO:0016485 163 0.029
negative regulation of lymphocyte proliferation GO:0050672 45 0.029
Mouse
compound eye development GO:0048749 1 0.029
regulation of cellular catabolic process GO:0031329 242 0.028
Mouse
rhythmic process GO:0048511 174 0.028
purine containing compound metabolic process GO:0072521 311 0.028
pyroptosis GO:0070269 8 0.028
Mouse
regulation of activated t cell proliferation GO:0046006 16 0.028
Mouse
hexose metabolic process GO:0019318 98 0.028
regulation of protein kinase activity GO:0045859 232 0.028
Mouse
ion transmembrane transport GO:0034220 361 0.028
adaptive immune response GO:0002250 155 0.028
negative regulation of necrotic cell death GO:0060547 11 0.028
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.028
positive regulation of cell cycle GO:0045787 92 0.027
ribonucleoside triphosphate catabolic process GO:0009203 199 0.027
nucleoside monophosphate metabolic process GO:0009123 85 0.027
lymphocyte mediated immunity GO:0002449 139 0.027
regulation of establishment of protein localization GO:0070201 181 0.027
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.027
cellular response to molecule of bacterial origin GO:0071219 83 0.027
ribonucleotide catabolic process GO:0009261 208 0.027
negative regulation of cellular component organization GO:0051129 194 0.027
negative regulation of lymphocyte activation GO:0051250 91 0.027
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.027
regulation of interleukin 8 production GO:0032677 3 0.027
inorganic ion transmembrane transport GO:0098660 234 0.027
cellular response to oxidative stress GO:0034599 76 0.027
Mouse
lymphocyte proliferation GO:0046651 164 0.026
Mouse
negative regulation of leukocyte proliferation GO:0070664 46 0.026
Mouse
sequestering of calcium ion GO:0051208 18 0.026
male gamete generation GO:0048232 285 0.026
regulation of inflammatory response GO:0050727 147 0.026
Mouse
cation transmembrane transport GO:0098655 266 0.026
cellular response to hormone stimulus GO:0032870 150 0.026
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.026
blood vessel morphogenesis GO:0048514 285 0.026
Mouse
amine metabolic process GO:0009308 45 0.025
muscle tissue development GO:0060537 308 0.025
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.025
Mouse
response to atp GO:0033198 8 0.025
Mouse
cellular amide metabolic process GO:0043603 58 0.025
cellular response to acid chemical GO:0071229 68 0.025
mitotic cell cycle process GO:1903047 159 0.025
response to oxidative stress GO:0006979 123 0.025
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.025
signal transduction in absence of ligand GO:0038034 55 0.025
Mouse
ribonucleoside catabolic process GO:0042454 206 0.025
cellular response to cytokine stimulus GO:0071345 189 0.025
transmembrane transport GO:0055085 412 0.025
interleukin 8 production GO:0032637 4 0.025
positive regulation of defense response GO:0031349 124 0.025
single organism cell adhesion GO:0098602 156 0.024
neuron apoptotic process GO:0051402 142 0.024
positive regulation of lymphocyte activation GO:0051251 140 0.024
positive regulation of protein modification process GO:0031401 299 0.024
protein oligomerization GO:0051259 67 0.024
positive regulation of cell activation GO:0050867 158 0.024
intracellular protein transport GO:0006886 204 0.024
lymphocyte differentiation GO:0030098 242 0.024
cellular component disassembly involved in execution phase of apoptosis GO:0006921 9 0.024
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.024
Mouse
regulation of cell motility GO:2000145 236 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
antigen receptor mediated signaling pathway GO:0050851 64 0.024
purine nucleoside triphosphate metabolic process GO:0009144 226 0.024
negative regulation of apoptotic signaling pathway GO:2001234 104 0.023
gland development GO:0048732 330 0.023
spermatogenesis GO:0007283 284 0.023
small gtpase mediated signal transduction GO:0007264 97 0.023
dna catabolic process endonucleolytic GO:0000737 15 0.023
Mouse
regulation of innate immune response GO:0045088 91 0.023
positive regulation of organelle organization GO:0010638 128 0.023
regulation of hormone levels GO:0010817 211 0.023
actin filament organization GO:0007015 113 0.023
glycosyl compound catabolic process GO:1901658 206 0.023
cellular response to external stimulus GO:0071496 88 0.023
lymphocyte apoptotic process GO:0070227 54 0.023
Mouse
regulation of cellular response to stress GO:0080135 159 0.023
gtp metabolic process GO:0046039 144 0.023
purine containing compound catabolic process GO:0072523 213 0.022
regulation of homeostatic process GO:0032844 182 0.022
regulation of organelle organization GO:0033043 289 0.022
blood circulation GO:0008015 195 0.022
respiratory system development GO:0060541 190 0.022
response to oxygen levels GO:0070482 62 0.022
Mouse
metal ion homeostasis GO:0055065 189 0.022
sensory perception of mechanical stimulus GO:0050954 107 0.022
Mouse
wnt signaling pathway GO:0016055 188 0.022
synaptic transmission GO:0007268 329 0.022
apoptotic nuclear changes GO:0030262 9 0.022
Mouse
stem cell differentiation GO:0048863 268 0.021
cellular chemical homeostasis GO:0055082 215 0.021
regulation of cysteine type endopeptidase activity GO:2000116 65 0.021
Mouse
regulation of autophagy GO:0010506 30 0.021
Mouse
positive regulation of myeloid cell differentiation GO:0045639 43 0.021
locomotory behavior GO:0007626 195 0.021
angiogenesis GO:0001525 201 0.021
Mouse
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.021
glycoprotein metabolic process GO:0009100 116 0.021
regulation of reactive oxygen species metabolic process GO:2000377 40 0.021
cellular modified amino acid metabolic process GO:0006575 63 0.021
regulation of b cell activation GO:0050864 81 0.021
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.021
glycosylation GO:0070085 62 0.021
carboxylic acid transport GO:0046942 100 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
regulation of mitochondrial membrane potential GO:0051881 17 0.021
Mouse
cellular carbohydrate metabolic process GO:0044262 119 0.020
regulation of cell migration GO:0030334 219 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
extracellular matrix organization GO:0030198 147 0.020
organelle assembly GO:0070925 177 0.020
endomembrane system organization GO:0010256 147 0.020
positive regulation of interleukin 1 alpha secretion GO:0050717 3 0.020
Mouse
sulfur compound metabolic process GO:0006790 100 0.020
myeloid leukocyte activation GO:0002274 83 0.020
pattern recognition receptor signaling pathway GO:0002221 47 0.020
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.020
Mouse
ribonucleoside metabolic process GO:0009119 245 0.020
regulation of mapk cascade GO:0043408 248 0.020
actin filament polymerization GO:0030041 44 0.020
regulation of neuron death GO:1901214 134 0.020
positive regulation of protein transport GO:0051222 93 0.020
Mouse
b cell differentiation GO:0030183 78 0.020
epithelial cell proliferation GO:0050673 174 0.020
nucleoside catabolic process GO:0009164 206 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
toll like receptor signaling pathway GO:0002224 38 0.019
positive regulation of neuron apoptotic process GO:0043525 25 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
regulation of actin filament polymerization GO:0030833 38 0.019
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
sensory perception of sound GO:0007605 97 0.019
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
cognition GO:0050890 149 0.019
macromolecule glycosylation GO:0043413 55 0.019
response to light stimulus GO:0009416 135 0.019
regulation of interleukin 1 alpha secretion GO:0050705 3 0.019
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.019
striated muscle myosin thick filament assembly GO:0071688 1 0.019
cellular response to organonitrogen compound GO:0071417 145 0.019
myosin filament organization GO:0031033 3 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
regulation of lipid metabolic process GO:0019216 118 0.019
monocarboxylic acid metabolic process GO:0032787 191 0.019
oocyte construction GO:0007308 2 0.019
organophosphate biosynthetic process GO:0090407 122 0.019
organelle localization GO:0051640 179 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
neuron death GO:0070997 154 0.019
engulfment of apoptotic cell GO:0043652 3 0.019
hepatocyte apoptotic process GO:0097284 11 0.019
Mouse
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.019
cytokine secretion GO:0050663 72 0.019
Mouse
response to acid chemical GO:0001101 111 0.019
protein import into nucleus GO:0006606 95 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
regulation of myeloid leukocyte differentiation GO:0002761 58 0.019
response to uv GO:0009411 44 0.019
production of molecular mediator of immune response GO:0002440 103 0.019
purine nucleotide catabolic process GO:0006195 211 0.018
regulation of neuron apoptotic process GO:0043523 122 0.018
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.018
covalent chromatin modification GO:0016569 163 0.018
nucleotide biosynthetic process GO:0009165 78 0.018
spermatid development GO:0007286 108 0.018
cellular protein complex assembly GO:0043623 116 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
glucose metabolic process GO:0006006 92 0.018
positive regulation of cytokine production GO:0001819 174 0.018
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.018
lung development GO:0030324 164 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
striated muscle cell development GO:0055002 125 0.018
cytokine mediated signaling pathway GO:0019221 115 0.018
tube formation GO:0035148 140 0.018
Mouse
lymphocyte activation involved in immune response GO:0002285 93 0.018
positive regulation of protein complex assembly GO:0031334 45 0.018
mitotic cell cycle GO:0000278 195 0.018
negative regulation of cell cycle GO:0045786 123 0.018
Mouse
cellular protein catabolic process GO:0044257 155 0.018
regulation of wnt signaling pathway GO:0030111 123 0.018
organic acid transport GO:0015849 101 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.018
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.018
anion transport GO:0006820 177 0.018
cellular metal ion homeostasis GO:0006875 151 0.017
dephosphorylation GO:0016311 129 0.017
chromatin modification GO:0016568 187 0.017
response to radiation GO:0009314 165 0.017
divalent inorganic cation transport GO:0072511 178 0.017
cell substrate adhesion GO:0031589 130 0.017
carbohydrate homeostasis GO:0033500 128 0.017
digestive tract development GO:0048565 190 0.017
actin polymerization or depolymerization GO:0008154 54 0.017
ras protein signal transduction GO:0007265 77 0.017
protein glycosylation GO:0006486 55 0.017
negative regulation of nervous system development GO:0051961 156 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
natural killer cell proliferation GO:0001787 3 0.017
positive regulation of cellular component biogenesis GO:0044089 94 0.017
translation GO:0006412 93 0.017
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.017
regulation of system process GO:0044057 200 0.017
response to growth factor GO:0070848 198 0.017
positive regulation of leukocyte differentiation GO:1902107 86 0.017
response to nutrient levels GO:0031667 109 0.017
regulation of neuron differentiation GO:0045664 281 0.017
developmental maturation GO:0021700 193 0.017
lateral inhibition GO:0046331 1 0.017
regulation of b cell proliferation GO:0030888 39 0.017
Mouse
glucose homeostasis GO:0042593 128 0.017
citrate metabolic process GO:0006101 3 0.017
extracellular structure organization GO:0043062 148 0.017
maintenance of location GO:0051235 89 0.017
erythrocyte differentiation GO:0030218 88 0.017
glycoprotein biosynthetic process GO:0009101 89 0.017
negative regulation of cell development GO:0010721 169 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
establishment of protein localization to organelle GO:0072594 118 0.017
inorganic cation transmembrane transport GO:0098662 207 0.016
regulation of ion transport GO:0043269 215 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
Mouse
regulation of actin nucleation GO:0051125 4 0.016
cellular response to extracellular stimulus GO:0031668 81 0.016
spermatid differentiation GO:0048515 115 0.016
ribonucleoside monophosphate metabolic process GO:0009161 80 0.016
nucleoside metabolic process GO:0009116 246 0.016
wound healing GO:0042060 157 0.016
antigen processing and presentation GO:0019882 47 0.016
phagocytosis GO:0006909 66 0.016
regulation of actin filament based process GO:0032970 99 0.016
divalent metal ion transport GO:0070838 172 0.016
respiratory tube development GO:0030323 167 0.016
positive regulation of t cell activation GO:0050870 101 0.016
amide transport GO:0042886 138 0.016
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.016
Mouse
response to alcohol GO:0097305 48 0.016
Mouse
cellular response to topologically incorrect protein GO:0035967 25 0.015
Mouse
t cell receptor signaling pathway GO:0050852 46 0.015
axonogenesis GO:0007409 274 0.015
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.015
calcium ion homeostasis GO:0055074 127 0.015
myosin filament assembly GO:0031034 2 0.015
response to peptide GO:1901652 136 0.015
fatty acid metabolic process GO:0006631 121 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
positive regulation of cell development GO:0010720 237 0.015
urogenital system development GO:0001655 261 0.015
stem cell development GO:0048864 219 0.015
methylation GO:0032259 134 0.015
regulation of actin filament length GO:0030832 45 0.015
positive regulation of growth GO:0045927 104 0.015
positive regulation of neuron death GO:1901216 28 0.015
regulation of adaptive immune response GO:0002819 90 0.015
positive regulation of interleukin 1 secretion GO:0050716 14 0.015
Mouse
protein localization to nucleus GO:0034504 121 0.015
sensory organ morphogenesis GO:0090596 242 0.015
regulation of myeloid cell differentiation GO:0045637 96 0.015
canonical wnt signaling pathway GO:0060070 130 0.015
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.014
leukocyte mediated cytotoxicity GO:0001909 62 0.014
negative regulation of immune effector process GO:0002698 55 0.014
cellular ion homeostasis GO:0006873 165 0.014
chromatin organization GO:0006325 206 0.014
negative regulation of synapse assembly GO:0051964 3 0.014
regulation of actin cytoskeleton organization GO:0032956 84 0.014
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.014
Mouse
actin cytoskeleton organization GO:0030036 220 0.014
generation of precursor metabolites and energy GO:0006091 103 0.014
forebrain development GO:0030900 302 0.014
multicellular organism growth GO:0035264 161 0.014
digestive system development GO:0055123 200 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
cellular calcium ion homeostasis GO:0006874 119 0.014
regulation of mast cell differentiation GO:0060375 3 0.014
positive regulation of secretion GO:0051047 130 0.014
Mouse
regulation of interferon gamma production GO:0032649 57 0.014
regulation of protein secretion GO:0050708 82 0.014
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.014
regulation of lymphocyte mediated immunity GO:0002706 84 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
organic anion transport GO:0015711 137 0.014
negative regulation of b cell proliferation GO:0030889 13 0.014
Mouse
lipid localization GO:0010876 126 0.014
mast cell proliferation GO:0070662 4 0.014
atp metabolic process GO:0046034 75 0.014
regulation of cytokine secretion GO:0050707 61 0.014
Mouse
t cell differentiation GO:0030217 174 0.014
alpha beta t cell differentiation GO:0046632 69 0.014
regulation of cell adhesion GO:0030155 154 0.014
endoplasmic reticulum unfolded protein response GO:0030968 19 0.014
Mouse
protein polymerization GO:0051258 57 0.014
oogenesis GO:0048477 56 0.013
autophagy GO:0006914 45 0.013
Mouse
cell activation involved in immune response GO:0002263 126 0.013
connective tissue development GO:0061448 179 0.013
positive regulation of podosome assembly GO:0071803 3 0.013
positive regulation of interferon alpha production GO:0032727 4 0.013
protein localization to membrane GO:0072657 108 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
peptidyl tyrosine phosphorylation GO:0018108 143 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
mapk cascade GO:0000165 281 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
plasma membrane organization GO:0007009 90 0.013
regulation of defense response to bacterium GO:1900424 3 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
anatomical structure homeostasis GO:0060249 145 0.013
lipid homeostasis GO:0055088 63 0.013
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.013
gonad development GO:0008406 141 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.013
regulation of antimicrobial humoral response GO:0002759 3 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
immune effector process GO:0002252 321 0.013
protein ubiquitination GO:0016567 171 0.013

Casp7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.061
disease of cellular proliferation DOID:14566 0 0.061
organ system cancer DOID:0050686 0 0.061
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
gastrointestinal system cancer DOID:3119 0 0.014