Mus musculus

63 known processes

Sema4c

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C

(Aliases: mKIAA1739,Semai,AI426163,Semaf,Semacl1)

Sema4c biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of tissue polarity GO:0007164 28 0.160
regulation of cellular catabolic process GO:0031329 242 0.111
Mouse
establishment of planar polarity GO:0001736 28 0.104
synaptic transmission GO:0007268 329 0.097
regulation of neuron differentiation GO:0045664 281 0.094
Mouse
locomotory behavior GO:0007626 195 0.089
Fly
morphogenesis of a polarized epithelium GO:0001738 37 0.089
transmembrane transport GO:0055085 412 0.085
ion transmembrane transport GO:0034220 361 0.084
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.076
positive regulation of nervous system development GO:0051962 221 0.064
Mouse
ubiquitin dependent protein catabolic process GO:0006511 129 0.063
cellular amino acid metabolic process GO:0006520 103 0.062
nucleotide metabolic process GO:0009117 332 0.060
Mouse
regulation of neuron projection development GO:0010975 169 0.060
Mouse
protein processing GO:0016485 163 0.058
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.056
negative regulation of cellular protein metabolic process GO:0032269 247 0.055
Mouse
posttranscriptional regulation of gene expression GO:0010608 155 0.054
macromolecule catabolic process GO:0009057 281 0.054
cellular protein catabolic process GO:0044257 155 0.053
cell adhesion GO:0007155 329 0.050
Worm
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.049
amine metabolic process GO:0009308 45 0.048
cellular macromolecule catabolic process GO:0044265 206 0.047
cation transmembrane transport GO:0098655 266 0.047
ribonucleoside triphosphate catabolic process GO:0009203 199 0.047
Mouse
ras protein signal transduction GO:0007265 77 0.046
modification dependent macromolecule catabolic process GO:0043632 133 0.046
leukocyte differentiation GO:0002521 342 0.046
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.045
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.045
protein catabolic process GO:0030163 221 0.045
intracellular protein transport GO:0006886 204 0.043
immune effector process GO:0002252 321 0.043
Mouse
regulation of secretion GO:0051046 274 0.042
cellular amine metabolic process GO:0044106 44 0.042
cation transport GO:0006812 399 0.039
epithelial tube morphogenesis GO:0060562 303 0.039
nitrogen compound transport GO:0071705 271 0.039
positive regulation of cellular catabolic process GO:0031331 148 0.039
Mouse
urogenital system development GO:0001655 261 0.039
kidney development GO:0001822 213 0.038
purine nucleoside metabolic process GO:0042278 241 0.038
Mouse
renal system development GO:0072001 225 0.037
forebrain development GO:0030900 302 0.037
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.037
axonogenesis GO:0007409 274 0.036
Mouse Worm Fly
regulation of transferase activity GO:0051338 263 0.036
skeletal system development GO:0001501 356 0.036
Mouse
compound eye development GO:0048749 1 0.036
purine containing compound metabolic process GO:0072521 311 0.035
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.035
regulation of cell projection organization GO:0031344 206 0.035
Mouse
male courtship behavior GO:0008049 2 0.035
nucleobase containing small molecule metabolic process GO:0055086 352 0.035
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.035
Mouse
angiogenesis GO:0001525 201 0.035
Mouse
inorganic cation transmembrane transport GO:0098662 207 0.035
inorganic ion transmembrane transport GO:0098660 234 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
modification dependent protein catabolic process GO:0019941 133 0.034
cell division GO:0051301 120 0.034
regulation of hormone levels GO:0010817 211 0.033
aromatic compound catabolic process GO:0019439 286 0.033
Mouse
lateral inhibition GO:0046331 1 0.033
maternal determination of anterior posterior axis embryo GO:0008358 2 0.032
purine nucleoside triphosphate catabolic process GO:0009146 203 0.032
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.032
regulation of cellular amino acid metabolic process GO:0006521 5 0.032
dendrite development GO:0016358 115 0.032
Mouse Fly
morphogenesis of a branching structure GO:0001763 203 0.031
Mouse
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.031
anion transport GO:0006820 177 0.031
lymphocyte differentiation GO:0030098 242 0.031
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.030
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.030
protein maturation GO:0051604 176 0.030
organic acid transport GO:0015849 101 0.030
organic anion transport GO:0015711 137 0.030
nucleotide catabolic process GO:0009166 217 0.030
Mouse
ribonucleotide metabolic process GO:0009259 291 0.029
Mouse
tissue migration GO:0090130 68 0.029
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
negative regulation of immune system process GO:0002683 209 0.029
ribonucleotide catabolic process GO:0009261 208 0.029
Mouse
regulation of protein localization GO:0032880 231 0.029
glycosyl compound catabolic process GO:1901658 206 0.028
Mouse
regulation of secretion by cell GO:1903530 249 0.028
carbohydrate metabolic process GO:0005975 230 0.028
blood vessel morphogenesis GO:0048514 285 0.028
Mouse
response to organonitrogen compound GO:0010243 246 0.027
protein targeting GO:0006605 143 0.027
adult behavior GO:0030534 135 0.027
Fly
protein ubiquitination GO:0016567 171 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
Mouse
regulation of protein catabolic process GO:0042176 108 0.027
ossification GO:0001503 216 0.027
Mouse
developmental maturation GO:0021700 193 0.027
Mouse
spermatogenesis GO:0007283 284 0.027
carboxylic acid transport GO:0046942 100 0.027
embryonic epithelial tube formation GO:0001838 130 0.027
regulation of synaptic plasticity GO:0048167 87 0.027
male gamete generation GO:0048232 285 0.026
cell maturation GO:0048469 127 0.026
carbohydrate derivative catabolic process GO:1901136 231 0.026
Mouse
muscle cell differentiation GO:0042692 261 0.026
cellular response to growth factor stimulus GO:0071363 197 0.026
regulation of protein kinase activity GO:0045859 232 0.026
limb development GO:0060173 166 0.026
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.026
neuron migration GO:0001764 122 0.026
Mouse
actin cytoskeleton organization GO:0030036 220 0.026
Worm
regionalization GO:0003002 337 0.026
Mouse
rho protein signal transduction GO:0007266 32 0.025
placenta development GO:0001890 140 0.025
purine ribonucleotide metabolic process GO:0009150 290 0.025
Mouse
camera type eye development GO:0043010 266 0.025
negative regulation of cell proliferation GO:0008285 296 0.025
proteasomal protein catabolic process GO:0010498 98 0.025
oocyte anterior posterior axis specification GO:0007314 2 0.025
regulation of ion transport GO:0043269 215 0.025
purine containing compound catabolic process GO:0072523 213 0.025
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.025
regulation of cell motility GO:2000145 236 0.024
Mouse Worm
regulation of cellular component biogenesis GO:0044087 181 0.024
negative regulation of cell activation GO:0050866 111 0.024
gtp catabolic process GO:0006184 143 0.024
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
Mouse
negative regulation of phosphorylation GO:0042326 166 0.024
Mouse
regulation of membrane potential GO:0042391 192 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.024
Mouse
response to growth factor GO:0070848 198 0.024
organophosphate catabolic process GO:0046434 232 0.023
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.023
microtubule based process GO:0007017 236 0.023
ameboidal type cell migration GO:0001667 128 0.023
Mouse
amino acid transport GO:0006865 61 0.023
regulation of kinase activity GO:0043549 249 0.023
t cell activation GO:0042110 289 0.023
Mouse
regulation of system process GO:0044057 200 0.023
Mouse
wnt signaling pathway GO:0016055 188 0.023
negative regulation of lymphocyte activation GO:0051250 91 0.023
regulation of nucleoside metabolic process GO:0009118 130 0.023
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
ribonucleoside catabolic process GO:0042454 206 0.023
Mouse
negative regulation of cell development GO:0010721 169 0.023
Mouse
glycosyl compound metabolic process GO:1901657 246 0.023
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.023
Mouse
cellular response to dna damage stimulus GO:0006974 207 0.022
cellular ketone metabolic process GO:0042180 84 0.022
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
Mouse
protein modification by small protein conjugation GO:0032446 187 0.022
epithelium migration GO:0090132 63 0.022
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.022
Mouse
positive regulation of apoptotic process GO:0043065 217 0.022
negative regulation of protein phosphorylation GO:0001933 126 0.022
Mouse
retina development in camera type eye GO:0060041 119 0.022
organonitrogen compound biosynthetic process GO:1901566 192 0.022
sensory organ morphogenesis GO:0090596 242 0.022
regulation of ras protein signal transduction GO:0046578 114 0.022
Mouse
positive regulation of transferase activity GO:0051347 167 0.021
response to lipopolysaccharide GO:0032496 128 0.021
sensory perception GO:0007600 245 0.021
regulation of cell cycle GO:0051726 281 0.021
muscle tissue development GO:0060537 308 0.021
regulation of protein stability GO:0031647 52 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.021
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.021
Mouse
pole plasm assembly GO:0007315 2 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
Mouse
positive regulation of cell development GO:0010720 237 0.021
Mouse
regulation of organelle organization GO:0033043 289 0.021
Worm
lipid transport GO:0006869 98 0.021
neuron projection guidance GO:0097485 141 0.021
Mouse Worm Fly
ureteric bud development GO:0001657 94 0.021
positive regulation of protein kinase activity GO:0045860 144 0.020
positive regulation of neuron differentiation GO:0045666 141 0.020
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
canonical wnt signaling pathway GO:0060070 130 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
primary neural tube formation GO:0014020 95 0.019
negative regulation of nervous system development GO:0051961 156 0.019
Mouse
sensory system development GO:0048880 3 0.019
regulation of anatomical structure size GO:0090066 178 0.019
Mouse
germ cell development GO:0007281 185 0.019
peptidyl amino acid modification GO:0018193 336 0.019
Mouse
embryonic organ morphogenesis GO:0048562 276 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.019
Mouse
learning or memory GO:0007611 148 0.019
cognition GO:0050890 149 0.019
respiratory system development GO:0060541 190 0.019
regulation of proteolysis GO:0030162 164 0.019
regulation of body fluid levels GO:0050878 162 0.019
embryonic placenta development GO:0001892 98 0.019
glycerolipid metabolic process GO:0046486 122 0.019
positive regulation of organelle organization GO:0010638 128 0.019
mitotic cell cycle GO:0000278 195 0.019
asymmetric stem cell division GO:0098722 3 0.019
neural tube closure GO:0001843 90 0.019
regulation of transmembrane transport GO:0034762 128 0.019
rhythmic process GO:0048511 174 0.018
glycerophospholipid metabolic process GO:0006650 71 0.018
cellular nitrogen compound catabolic process GO:0044270 280 0.018
Mouse
connective tissue development GO:0061448 179 0.018
cellular response to lipid GO:0071396 145 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.018
Mouse
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.018
cellular lipid metabolic process GO:0044255 323 0.018
establishment of protein localization to organelle GO:0072594 118 0.018
synapse organization GO:0050808 125 0.018
positive regulation of neuron projection development GO:0010976 79 0.018
Mouse
oxidation reduction process GO:0055114 342 0.018
appendage morphogenesis GO:0035107 149 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
Mouse
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.018
heterocycle catabolic process GO:0046700 280 0.018
Mouse
response to light stimulus GO:0009416 135 0.018
Fly
multicellular organism growth GO:0035264 161 0.018
circulatory system process GO:0003013 197 0.018
Mouse
cytokine production GO:0001816 319 0.018
negative regulation of t cell activation GO:0050868 65 0.017
morphogenesis of embryonic epithelium GO:0016331 159 0.017
regulation of cellular protein catabolic process GO:1903362 61 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.017
stem cell proliferation GO:0072089 117 0.017
regulation of leukocyte differentiation GO:1902105 159 0.017
neural precursor cell proliferation GO:0061351 121 0.017
membrane organization GO:0061024 245 0.017
wound healing GO:0042060 157 0.017
heart morphogenesis GO:0003007 178 0.017
cerebral cortex development GO:0021987 86 0.017
Mouse
digestive system development GO:0055123 200 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
Mouse
positive regulation of protein modification process GO:0031401 299 0.017
Mouse
protein localization to cell junction GO:1902414 3 0.017
oocyte axis specification GO:0007309 2 0.017
negative regulation of cellular catabolic process GO:0031330 47 0.017
nucleoside catabolic process GO:0009164 206 0.017
Mouse
purine nucleotide catabolic process GO:0006195 211 0.017
Mouse
positive regulation of growth GO:0045927 104 0.017
divalent metal ion transport GO:0070838 172 0.016
regulation of t cell activation GO:0050863 170 0.016
gene silencing by rna GO:0031047 19 0.016
positive regulation of kinase activity GO:0033674 155 0.016
striated muscle tissue development GO:0014706 293 0.016
microtubule cytoskeleton organization GO:0000226 157 0.016
protein localization to adherens junction GO:0071896 2 0.016
regulation of postsynaptic membrane potential GO:0060078 48 0.016
neural tube development GO:0021915 160 0.016
developmental cell growth GO:0048588 84 0.016
Mouse
ear development GO:0043583 200 0.016
b cell differentiation GO:0030183 78 0.016
regulation of cellular response to stress GO:0080135 159 0.016
Human
photoreceptor cell differentiation GO:0046530 52 0.016
response to radiation GO:0009314 165 0.016
Fly
branching morphogenesis of an epithelial tube GO:0048754 159 0.016
positive regulation of cell death GO:0010942 224 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
blood circulation GO:0008015 195 0.016
Mouse
regulation of mapk cascade GO:0043408 248 0.016
Human
regulation of cytoskeleton organization GO:0051493 122 0.016
Worm
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
regulation of cell growth GO:0001558 91 0.016
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
regulation of gtp catabolic process GO:0033124 113 0.016
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.016
Mouse
chemotaxis GO:0006935 247 0.016
Mouse Worm Fly
actin polymerization or depolymerization GO:0008154 54 0.016
negative regulation of intracellular transport GO:0032387 38 0.015
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
glycerolipid biosynthetic process GO:0045017 50 0.015
cellular homeostasis GO:0019725 240 0.015
muscle system process GO:0003012 141 0.015
cellular response to molecule of bacterial origin GO:0071219 83 0.015
skeletal system morphogenesis GO:0048705 203 0.015
regulation of cytokine production GO:0001817 266 0.015
regulation of multi organism process GO:0043900 111 0.015
endomembrane system organization GO:0010256 147 0.015
embryonic appendage morphogenesis GO:0035113 126 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
response to transforming growth factor beta GO:0071559 88 0.015
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 3 0.015
regulation of cell migration GO:0030334 219 0.015
Mouse Worm
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.015
gene silencing by mirna GO:0035195 10 0.015
endocytosis GO:0006897 168 0.015
lipid localization GO:0010876 126 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
Mouse
oocyte construction GO:0007308 2 0.015
lung development GO:0030324 164 0.015
extracellular matrix organization GO:0030198 147 0.015
inflammatory response GO:0006954 244 0.015
adaptive immune response GO:0002250 155 0.015
Mouse
myeloid cell differentiation GO:0030099 233 0.015
phospholipid metabolic process GO:0006644 87 0.015
detection of stimulus GO:0051606 84 0.015
b cell activation GO:0042113 161 0.015
nucleoside metabolic process GO:0009116 246 0.015
Mouse
negative regulation of protein catabolic process GO:0042177 36 0.014
regulation of protein complex assembly GO:0043254 83 0.014
gene silencing GO:0016458 38 0.014
regulation of ion transmembrane transport GO:0034765 119 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
Mouse
neuromuscular process controlling balance GO:0050885 59 0.014
synapse assembly GO:0007416 56 0.014
ear morphogenesis GO:0042471 118 0.014
tube formation GO:0035148 140 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
regulation of cellular response to growth factor stimulus GO:0090287 82 0.014
negative regulation of wnt signaling pathway GO:0030178 73 0.014
negative regulation of molecular function GO:0044092 258 0.014
Mouse
positive regulation of ras gtpase activity GO:0032320 65 0.014
Mouse
response to amino acid GO:0043200 37 0.014
multicellular organismal signaling GO:0035637 91 0.014
cytoplasmic transport GO:0016482 234 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
Mouse
heart contraction GO:0060047 93 0.014
Mouse
response to acid chemical GO:0001101 111 0.014
membrane depolarization GO:0051899 64 0.014
apoptotic signaling pathway GO:0097190 306 0.014
artery development GO:0060840 53 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.014
positive regulation of gtpase activity GO:0043547 85 0.014
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.014
myosin filament organization GO:0031033 3 0.014
glycerophospholipid biosynthetic process GO:0046474 32 0.014
respiratory tube development GO:0030323 167 0.014
negative regulation of protein kinase activity by regulation of protein phosphorylation GO:0044387 2 0.014
directional locomotion GO:0033058 3 0.014
sensory perception of mechanical stimulus GO:0050954 107 0.014
nuclear transport GO:0051169 139 0.014
regulation of protein transport GO:0051223 163 0.014
regulation of response to wounding GO:1903034 189 0.014
bone development GO:0060348 120 0.014
Mouse
meiotic cell cycle GO:0051321 122 0.014
spermatid development GO:0007286 108 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
gtp metabolic process GO:0046039 144 0.013
Mouse
protein import into nucleus GO:0006606 95 0.013
regulation of cell activation GO:0050865 289 0.013
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.013
cation homeostasis GO:0055080 212 0.013
positive regulation of leukocyte differentiation GO:1902107 86 0.013
basal protein localization GO:0045175 1 0.013
transmission of nerve impulse GO:0019226 76 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.013
facioacoustic ganglion development GO:1903375 3 0.013
Mouse
production of molecular mediator of immune response GO:0002440 103 0.013
protein localization to organelle GO:0033365 185 0.013
organelle fission GO:0048285 170 0.013
photoreceptor cell development GO:0042461 40 0.013
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.013
trunk segmentation GO:0035290 4 0.013
Mouse
neuronal action potential GO:0019228 54 0.013
embryonic digit morphogenesis GO:0042733 56 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
establishment of organelle localization GO:0051656 122 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
Mouse
positive regulation of cellular component biogenesis GO:0044089 94 0.013
regulation of cell cycle process GO:0010564 160 0.013
neural tube formation GO:0001841 108 0.013
multi multicellular organism process GO:0044706 109 0.013
regulation of organ morphogenesis GO:2000027 144 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
epithelial cell migration GO:0010631 63 0.013
Mouse
lateral line system development GO:0048925 1 0.013
lipid biosynthetic process GO:0008610 179 0.013
small molecule biosynthetic process GO:0044283 132 0.013
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.013
cerebral cortex tangential migration using cell axon interactions GO:0021824 3 0.013
Mouse
gonad development GO:0008406 141 0.013
Mouse
positive regulation of programmed cell death GO:0043068 218 0.012
regulation of metal ion transport GO:0010959 106 0.012
alpha beta t cell activation GO:0046631 91 0.012
Mouse
negative regulation of leukocyte differentiation GO:1902106 51 0.012
regulation of actin filament based process GO:0032970 99 0.012
Worm
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
mitotic cytokinesis GO:0000281 4 0.012
development of primary sexual characteristics GO:0045137 143 0.012
Mouse
neuroblast proliferation GO:0007405 49 0.012
regulation of purine nucleotide catabolic process GO:0033121 122 0.012
Mouse
inner ear morphogenesis GO:0042472 101 0.012
regulation of protein maturation GO:1903317 96 0.012
limb morphogenesis GO:0035108 149 0.012
dna metabolic process GO:0006259 303 0.012
inter male aggressive behavior GO:0002121 3 0.012
negative regulation of protein maturation GO:1903318 79 0.012
negative regulation of protein transport GO:0051224 46 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.012
t cell differentiation in thymus GO:0033077 77 0.012
response to organic cyclic compound GO:0014070 198 0.012
fat cell differentiation GO:0045444 160 0.012
nucleoside phosphate metabolic process GO:0006753 338 0.012
Mouse
female gamete generation GO:0007292 74 0.012
actin filament organization GO:0007015 113 0.012
cellular response to amino acid stimulus GO:0071230 29 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
hindbrain development GO:0030902 128 0.012
epithelial cell proliferation GO:0050673 174 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.012
mitotic cell cycle process GO:1903047 159 0.012
leukocyte mediated immunity GO:0002443 174 0.012
rna interference GO:0016246 2 0.012
response to oxygen levels GO:0070482 62 0.012
single organismal cell cell adhesion GO:0016337 131 0.012
embryonic limb morphogenesis GO:0030326 126 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
cytokinetic process GO:0032506 2 0.012
negative regulation of proteolysis GO:0045861 74 0.012
stress activated protein kinase signaling cascade GO:0031098 81 0.012
Human
cerebellum development GO:0021549 77 0.011
t cell differentiation GO:0030217 174 0.011
Mouse
regulation of neurotransmitter levels GO:0001505 87 0.011
alpha amino acid metabolic process GO:1901605 59 0.011
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.011
myosin filament assembly GO:0031034 2 0.011
organelle localization GO:0051640 179 0.011
Mouse
extracellular structure organization GO:0043062 148 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
regulation of ovulation GO:0060278 3 0.011
spermatid differentiation GO:0048515 115 0.011
blastocyst development GO:0001824 80 0.011
regulation of defense response GO:0031347 233 0.011
regulation of circadian rhythm GO:0042752 58 0.011
neuron projection extension GO:1990138 64 0.011
Mouse
regulation of establishment of protein localization GO:0070201 181 0.011
neuromuscular process GO:0050905 99 0.011
dorsal ventral axon guidance GO:0033563 3 0.011
actin filament polymerization GO:0030041 44 0.011
positive regulation of cell projection organization GO:0031346 95 0.011
Mouse
defense response to other organism GO:0098542 197 0.011
nephron development GO:0072006 109 0.011
regulation of ossification GO:0030278 112 0.011
Mouse
carbohydrate homeostasis GO:0033500 128 0.011
negative regulation of transferase activity GO:0051348 85 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
telencephalon development GO:0021537 186 0.011
Mouse
positive regulation of protein catabolic process GO:0045732 60 0.011
cell recognition GO:0008037 83 0.011
Mouse Worm Fly
calcium ion transport GO:0006816 159 0.011
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.011
myeloid cell homeostasis GO:0002262 114 0.011
tube closure GO:0060606 91 0.011
glucose homeostasis GO:0042593 128 0.011
regulation of stress activated mapk cascade GO:0032872 69 0.011
Human
regulation of blood pressure GO:0008217 93 0.011
muscle contraction GO:0006936 101 0.011
epithelial tube formation GO:0072175 130 0.011
posttranscriptional gene silencing GO:0016441 10 0.011
cardiac chamber development GO:0003205 108 0.011
cellular protein complex assembly GO:0043623 116 0.011
posttranscriptional gene silencing by rna GO:0035194 10 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
Mouse
male sex differentiation GO:0046661 109 0.011
Mouse Worm
response to inorganic substance GO:0010035 96 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
mesodermal cell migration GO:0008078 4 0.011
nuclear division GO:0000280 158 0.011
phospholipid biosynthetic process GO:0008654 36 0.011
positive regulation of gtp catabolic process GO:0033126 85 0.011
Mouse
detection of external stimulus GO:0009581 61 0.011
ensheathment of neurons GO:0007272 76 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
Mouse
detection of abiotic stimulus GO:0009582 60 0.011
lymphocyte proliferation GO:0046651 164 0.010
skin development GO:0043588 220 0.010
cardiac septum development GO:0003279 59 0.010
monocarboxylic acid metabolic process GO:0032787 191 0.010
protein polymerization GO:0051258 57 0.010
amide transport GO:0042886 138 0.010
hormone secretion GO:0046879 128 0.010
response to extracellular stimulus GO:0009991 127 0.010
regulation of nucleotide metabolic process GO:0006140 169 0.010
Mouse
glutamate receptor signaling pathway GO:0007215 35 0.010
striated muscle myosin thick filament assembly GO:0071688 1 0.010

Sema4c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
immune system disease DOID:2914 0 0.013
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
central nervous system disease DOID:331 0 0.011