Mus musculus

0 known processes

Mus81

MUS81 endonuclease homolog (yeast)

(Aliases: AW045863,AI182501,1200008A18Rik)

Mus81 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell adhesion GO:0007155 329 0.143
regulation of cellular amino acid metabolic process GO:0006521 5 0.104
regulation of cellular amine metabolic process GO:0033238 20 0.090
skeletal system development GO:0001501 356 0.086
regulation of removal of superoxide radicals GO:2000121 4 0.086
regulation of cellular response to stress GO:0080135 159 0.084
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.082
regulation of kinase activity GO:0043549 249 0.078
regulation of cellular ketone metabolic process GO:0010565 66 0.066
cellular ketone metabolic process GO:0042180 84 0.066
small gtpase mediated signal transduction GO:0007264 97 0.064
regulation of proteolysis GO:0030162 164 0.060
regulation of cell projection organization GO:0031344 206 0.059
synaptic transmission GO:0007268 329 0.057
peptidyl amino acid modification GO:0018193 336 0.057
regulation of transferase activity GO:0051338 263 0.055
negative regulation of protein metabolic process GO:0051248 282 0.053
organelle assembly GO:0070925 177 0.052
regulation of reactive oxygen species metabolic process GO:2000377 40 0.052
microtubule based process GO:0007017 236 0.049
protein modification by small protein conjugation GO:0032446 187 0.049
positive regulation of cellular amine metabolic process GO:0033240 5 0.047
regulation of protein kinase activity GO:0045859 232 0.047
cellular amino acid metabolic process GO:0006520 103 0.046
anatomical structure homeostasis GO:0060249 145 0.045
negative regulation of protein phosphorylation GO:0001933 126 0.043
negative regulation of cellular amine metabolic process GO:0033239 1 0.042
protein ubiquitination GO:0016567 171 0.042
ras protein signal transduction GO:0007265 77 0.042
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.040
tissue homeostasis GO:0001894 115 0.040
histone modification GO:0016570 159 0.040
membrane organization GO:0061024 245 0.039
negative regulation of phosphorus metabolic process GO:0010563 184 0.038
cellular response to cytokine stimulus GO:0071345 189 0.037
establishment of organelle localization GO:0051656 122 0.037
amine metabolic process GO:0009308 45 0.035
protein modification by small protein conjugation or removal GO:0070647 207 0.034
positive regulation of transferase activity GO:0051347 167 0.034
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.033
respiratory tube development GO:0030323 167 0.033
regulation of protein localization GO:0032880 231 0.033
regulation of establishment of protein localization GO:0070201 181 0.032
negative regulation of protein modification process GO:0031400 163 0.032
chromatin organization GO:0006325 206 0.032
skeletal system morphogenesis GO:0048705 203 0.031
reactive oxygen species metabolic process GO:0072593 84 0.030
extracellular matrix organization GO:0030198 147 0.030
cellular response to growth factor stimulus GO:0071363 197 0.030
positive regulation of kinase activity GO:0033674 155 0.030
regulation of t cell activation GO:0050863 170 0.030
cytokine production GO:0001816 319 0.030
vesicle localization GO:0051648 86 0.030
intracellular protein transport GO:0006886 204 0.029
lung development GO:0030324 164 0.029
positive regulation of cell projection organization GO:0031346 95 0.029
organophosphate catabolic process GO:0046434 232 0.028
synapse organization GO:0050808 125 0.028
regulation of lymphocyte activation GO:0051249 240 0.028
regulation of cell activation GO:0050865 289 0.028
regulation of organelle organization GO:0033043 289 0.028
negative regulation of molecular function GO:0044092 258 0.027
response to transforming growth factor beta GO:0071559 88 0.027
positive regulation of cell development GO:0010720 237 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
striated muscle tissue development GO:0014706 293 0.025
negative regulation of phosphorylation GO:0042326 166 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
Human
carbohydrate metabolic process GO:0005975 230 0.025
regulation of ras protein signal transduction GO:0046578 114 0.025
t cell activation GO:0042110 289 0.024
covalent chromatin modification GO:0016569 163 0.024
camera type eye development GO:0043010 266 0.024
cellular response to oxygen radical GO:0071450 14 0.023
positive regulation of hydrolase activity GO:0051345 148 0.023
cilium assembly GO:0042384 81 0.023
regulation of secretion by cell GO:1903530 249 0.023
maintenance of location GO:0051235 89 0.022
regulation of protein serine threonine kinase activity GO:0071900 157 0.022
protein catabolic process GO:0030163 221 0.022
regulation of hormone levels GO:0010817 211 0.022
chromatin modification GO:0016568 187 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
regulation of cell substrate adhesion GO:0010810 73 0.022
nucleobase containing small molecule metabolic process GO:0055086 352 0.022
multicellular organismal homeostasis GO:0048871 164 0.021
regulation of mapk cascade GO:0043408 248 0.021
response to oxidative stress GO:0006979 123 0.021
positive regulation of cellular component biogenesis GO:0044089 94 0.021
bone development GO:0060348 120 0.021
superoxide metabolic process GO:0006801 27 0.021
tissue remodeling GO:0048771 102 0.021
negative regulation of kinase activity GO:0033673 81 0.021
positive regulation of cell adhesion GO:0045785 80 0.020
regulation of peptidase activity GO:0052547 96 0.020
regulation of hydrolase activity GO:0051336 246 0.020
response to growth factor GO:0070848 198 0.020
appendage morphogenesis GO:0035107 149 0.020
regulation of lymphocyte proliferation GO:0050670 117 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
synaptic vesicle localization GO:0097479 59 0.020
apoptotic signaling pathway GO:0097190 306 0.020
cell substrate adhesion GO:0031589 130 0.020
respiratory system development GO:0060541 190 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.019
synapse assembly GO:0007416 56 0.019
homeostasis of number of cells GO:0048872 210 0.019
digestive tract development GO:0048565 190 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
cytoplasmic transport GO:0016482 234 0.019
purine containing compound metabolic process GO:0072521 311 0.019
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.019
endocytosis GO:0006897 168 0.019
multicellular organismal signaling GO:0035637 91 0.019
mitotic cell cycle process GO:1903047 159 0.019
fat cell differentiation GO:0045444 160 0.019
phospholipid transport GO:0015914 21 0.019
regulation of cell cycle GO:0051726 281 0.019
cdc42 protein signal transduction GO:0032488 0 0.018
macromolecule catabolic process GO:0009057 281 0.018
Human
cellular macromolecule catabolic process GO:0044265 206 0.018
Human
response to reactive oxygen species GO:0000302 56 0.018
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
negative regulation of apoptotic signaling pathway GO:2001234 104 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
compound eye development GO:0048749 1 0.018
regulation of neuron differentiation GO:0045664 281 0.018
nucleotide catabolic process GO:0009166 217 0.018
dna metabolic process GO:0006259 303 0.018
Human
regulation of homeostatic process GO:0032844 182 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
regulation of cell motility GO:2000145 236 0.017
mitotic cell cycle GO:0000278 195 0.017
mapk cascade GO:0000165 281 0.017
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.017
organelle localization GO:0051640 179 0.017
connective tissue development GO:0061448 179 0.017
microtubule cytoskeleton organization GO:0000226 157 0.017
regulation of cell cycle process GO:0010564 160 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
lipid localization GO:0010876 126 0.017
inflammatory response GO:0006954 244 0.017
regulation of secretion GO:0051046 274 0.017
neuron death GO:0070997 154 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
Human
positive regulation of nervous system development GO:0051962 221 0.016
innate immune response GO:0045087 157 0.016
protein targeting GO:0006605 143 0.016
myeloid cell differentiation GO:0030099 233 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
heterocycle catabolic process GO:0046700 280 0.016
Human
protein localization to organelle GO:0033365 185 0.016
asymmetric stem cell division GO:0098722 3 0.016
response to organonitrogen compound GO:0010243 246 0.016
immune effector process GO:0002252 321 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
hormone secretion GO:0046879 128 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
cellular response to dna damage stimulus GO:0006974 207 0.016
Human
negative regulation of immune system process GO:0002683 209 0.016
regulation of t cell proliferation GO:0042129 92 0.016
cell type specific apoptotic process GO:0097285 268 0.016
cellular lipid metabolic process GO:0044255 323 0.016
cellular amine metabolic process GO:0044106 44 0.016
protein localization to membrane GO:0072657 108 0.016
fertilization GO:0009566 127 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
positive regulation of nitric oxide synthase activity GO:0051000 2 0.016
cellular response to oxidative stress GO:0034599 76 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.015
positive regulation of t cell activation GO:0050870 101 0.015
regulation of response to reactive oxygen species GO:1901031 9 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
limb morphogenesis GO:0035108 149 0.015
nucleoside phosphate metabolic process GO:0006753 338 0.015
regulation of intracellular transport GO:0032386 159 0.015
response to superoxide GO:0000303 16 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
positive regulation of cell substrate adhesion GO:0010811 47 0.015
spermatogenesis GO:0007283 284 0.015
chemotaxis GO:0006935 247 0.015
regulation of body fluid levels GO:0050878 162 0.015
regulation of defense response GO:0031347 233 0.015
steroid metabolic process GO:0008202 119 0.015
nuclear division GO:0000280 158 0.015
leukocyte differentiation GO:0002521 342 0.014
axonogenesis GO:0007409 274 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
regulation of ossification GO:0030278 112 0.014
positive regulation of cell activation GO:0050867 158 0.014
muscle tissue development GO:0060537 308 0.014
nitrogen compound transport GO:0071705 271 0.014
regulation of system process GO:0044057 200 0.014
nucleotide metabolic process GO:0009117 332 0.014
negative regulation of b cell receptor signaling pathway GO:0050859 4 0.014
positive regulation of neuron projection development GO:0010976 79 0.014
lipoprotein metabolic process GO:0042157 43 0.014
cellular protein catabolic process GO:0044257 155 0.014
chondrocyte differentiation GO:0002062 72 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
positive regulation of secretion by cell GO:1903532 114 0.014
cellular protein complex assembly GO:0043623 116 0.014
protein processing GO:0016485 163 0.014
maintenance of protein location in nucleus GO:0051457 2 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
positive regulation of peptidase activity GO:0010952 49 0.014
sterol transport GO:0015918 38 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
regulation of inflammatory response GO:0050727 147 0.014
cartilage development GO:0051216 140 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
response to lipopolysaccharide GO:0032496 128 0.013
leukocyte proliferation GO:0070661 172 0.013
triglyceride metabolic process GO:0006641 51 0.013
negative regulation of cell development GO:0010721 169 0.013
positive regulation of cytokine production GO:0001819 174 0.013
cilium morphogenesis GO:0060271 102 0.013
regulation of leukocyte proliferation GO:0070663 121 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
regulation of actin filament based process GO:0032970 99 0.013
regulation of cell adhesion GO:0030155 154 0.013
regulation of cell projection assembly GO:0060491 38 0.013
regulation of map kinase activity GO:0043405 120 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
dendrite development GO:0016358 115 0.013
protein maturation GO:0051604 176 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
peptidyl tyrosine phosphorylation GO:0018108 143 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
alcohol catabolic process GO:0046164 16 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
positive regulation of defense response GO:0031349 124 0.013
dephosphorylation GO:0016311 129 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
limb development GO:0060173 166 0.012
response to oxygen radical GO:0000305 16 0.012
skeletal muscle organ development GO:0060538 163 0.012
bone resorption GO:0045453 38 0.012
negative regulation of transferase activity GO:0051348 85 0.012
rna processing GO:0006396 105 0.012
sensory organ morphogenesis GO:0090596 242 0.012
muscle cell differentiation GO:0042692 261 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
endomembrane system organization GO:0010256 147 0.012
regulation of cell growth GO:0001558 91 0.012
positive regulation of intracellular transport GO:0032388 70 0.012
sterol esterification GO:0034434 3 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
negative regulation of cell cycle GO:0045786 123 0.012
negative regulation of mapk cascade GO:0043409 65 0.012
t cell proliferation GO:0042098 120 0.012
negative regulation of epidermal growth factor activated receptor activity GO:0007175 3 0.012
phospholipid metabolic process GO:0006644 87 0.012
positive regulation of immune effector process GO:0002699 107 0.012
negative regulation of immune effector process GO:0002698 55 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
regulation of cell migration GO:0030334 219 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
digestive system development GO:0055123 200 0.012
positive regulation of homeostatic process GO:0032846 64 0.012
embryonic organ morphogenesis GO:0048562 276 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
Human
acylglycerol metabolic process GO:0006639 55 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
regulation of beta amyloid clearance GO:1900221 1 0.011
cellular response to lipid GO:0071396 145 0.011
negative regulation of cell activation GO:0050866 111 0.011
asymmetric neuroblast division GO:0055059 1 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
lymphocyte proliferation GO:0046651 164 0.011
regulation of cellular component size GO:0032535 121 0.011
negative regulation of organelle organization GO:0010639 90 0.011
protein secretion GO:0009306 111 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
organophosphate ester transport GO:0015748 28 0.011
negative regulation of defense response GO:0031348 77 0.011
cell fate commitment GO:0045165 210 0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.011
positive regulation of map kinase activity GO:0043406 84 0.011
ossification GO:0001503 216 0.011
embryonic placenta development GO:0001892 98 0.011
dendritic spine maintenance GO:0097062 4 0.011
urogenital system development GO:0001655 261 0.011
cellular response to superoxide GO:0071451 14 0.011
cell growth GO:0016049 130 0.011
blood vessel morphogenesis GO:0048514 285 0.011
striated muscle cell development GO:0055002 125 0.011
glycerolipid biosynthetic process GO:0045017 50 0.010
establishment of vesicle localization GO:0051650 81 0.010
bone morphogenesis GO:0060349 78 0.010
aromatic compound catabolic process GO:0019439 286 0.010
Human
regulation of leukocyte differentiation GO:1902105 159 0.010
innate immune response in mucosa GO:0002227 3 0.010
cation transport GO:0006812 399 0.010
regulation of actin cytoskeleton organization GO:0032956 84 0.010
establishment or maintenance of neuroblast polarity GO:0045196 1 0.010
cholesterol transport GO:0030301 38 0.010
purine nucleoside triphosphate metabolic process GO:0009144 226 0.010
interspecies interaction between organisms GO:0044419 83 0.010
nucleoside catabolic process GO:0009164 206 0.010
transmembrane transport GO:0055085 412 0.010
organic hydroxy compound transport GO:0015850 93 0.010
renal system development GO:0072001 225 0.010
leukocyte mediated immunity GO:0002443 174 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
activation of mapk activity GO:0000187 59 0.010
glycoprotein metabolic process GO:0009100 116 0.010
adaptive immune response GO:0002250 155 0.010
regulation of protein targeting GO:1903533 61 0.010
exocytosis GO:0006887 121 0.010
positive regulation of protein modification process GO:0031401 299 0.010
purine nucleoside catabolic process GO:0006152 205 0.010
cellular component assembly involved in morphogenesis GO:0010927 139 0.010
response to epidermal growth factor GO:0070849 4 0.010
retina development in camera type eye GO:0060041 119 0.010
establishment of synaptic vesicle localization GO:0097480 57 0.010
acetylcholine transport GO:0015870 2 0.010
cerebellar cortex development GO:0021695 48 0.010
cholesterol esterification GO:0034435 3 0.010
positive regulation of neuron differentiation GO:0045666 141 0.010
heart morphogenesis GO:0003007 178 0.010
positive regulation of cellular catabolic process GO:0031331 148 0.010
protein import into nucleus GO:0006606 95 0.010
cell killing GO:0001906 67 0.010
kidney development GO:0001822 213 0.010
cellular homeostasis GO:0019725 240 0.010
negative regulation of cytokine production GO:0001818 84 0.010

Mus81 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
immune system disease DOID:2914 0 0.020
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.018
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
musculoskeletal system disease DOID:17 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
eye disease DOID:5614 0 0.010
central nervous system disease DOID:331 0 0.010
cardiovascular system disease DOID:1287 0 0.010
organ system cancer DOID:0050686 0 0.010
cancer DOID:162 0 0.010