Mus musculus

123 known processes

Il22

interleukin 22

(Aliases: IL-22a,IL-22,Iltif,MGC129417,MGC129416,ILTIFa)

Il22 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to lipid GO:0071396 145 0.498
Mouse
cytokine production GO:0001816 319 0.480
Mouse
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.308
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.297
activation of immune response GO:0002253 138 0.296
immunoglobulin mediated immune response GO:0016064 69 0.292
cellular amino acid metabolic process GO:0006520 103 0.281
cellular response to lipopolysaccharide GO:0071222 77 0.270
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.266
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.255
regulation of protein kinase activity GO:0045859 232 0.226
regulation of ion transport GO:0043269 215 0.225
humoral immune response GO:0006959 57 0.221
regulation of protein serine threonine kinase activity GO:0071900 157 0.219
t cell activation GO:0042110 289 0.218
regulation of t cell activation GO:0050863 170 0.198
regulation of defense response GO:0031347 233 0.198
regulation of apoptotic signaling pathway GO:2001233 197 0.197
Mouse
regulation of response to wounding GO:1903034 189 0.193
dna metabolic process GO:0006259 303 0.188
somatic diversification of immune receptors GO:0002200 53 0.185
i kappab kinase nf kappab signaling GO:0007249 85 0.184
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.183
chemotaxis GO:0006935 247 0.181
apoptotic signaling pathway GO:0097190 306 0.181
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.173
response to lipopolysaccharide GO:0032496 128 0.173
Mouse
regulation of growth of symbiont in host GO:0044126 19 0.171
Mouse
myeloid cell differentiation GO:0030099 233 0.170
positive regulation of protein modification process GO:0031401 299 0.169
organic acid transport GO:0015849 101 0.167
regulation of proteolysis GO:0030162 164 0.163
Mouse
regulation of protein transport GO:0051223 163 0.162
protein maturation GO:0051604 176 0.161
Mouse
regulation of erk1 and erk2 cascade GO:0070372 71 0.160
erk1 and erk2 cascade GO:0070371 77 0.157
regulation of lymphocyte activation GO:0051249 240 0.154
regulation of interleukin 10 secretion GO:2001179 4 0.148
regulation of cellular amine metabolic process GO:0033238 20 0.145
zymogen activation GO:0031638 41 0.143
activation of cysteine type endopeptidase activity GO:0097202 27 0.142
negative regulation of cell activation GO:0050866 111 0.141
Mouse
leukocyte mediated immunity GO:0002443 174 0.141
sensory perception GO:0007600 245 0.139
cellular response to cytokine stimulus GO:0071345 189 0.139
response to molecule of bacterial origin GO:0002237 143 0.139
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.137
Mouse
regulation of secretion GO:0051046 274 0.133
cellular chemical homeostasis GO:0055082 215 0.131
dna recombination GO:0006310 92 0.130
cytokine mediated signaling pathway GO:0019221 115 0.130
peptide transport GO:0015833 133 0.130
regulation of secretion by cell GO:1903530 249 0.129
regulation of lymphocyte mediated immunity GO:0002706 84 0.128
regulation of peptidase activity GO:0052547 96 0.128
Mouse
protein processing GO:0016485 163 0.127
Mouse
regulation of interferon gamma production GO:0032649 57 0.126
Mouse
negative regulation of molecular function GO:0044092 258 0.124
Mouse
leukocyte differentiation GO:0002521 342 0.123
regulation of transferase activity GO:0051338 263 0.122
positive regulation of proteolysis GO:0045862 85 0.122
Mouse
leukocyte proliferation GO:0070661 172 0.121
regulation of mapk cascade GO:0043408 248 0.121
cell type specific apoptotic process GO:0097285 268 0.121
regulation of acute inflammatory response GO:0002673 27 0.119
carbohydrate metabolic process GO:0005975 230 0.119
regulation of hormone secretion GO:0046883 88 0.118
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.118
cytokine biosynthetic process GO:0042089 68 0.118
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.117
regulation of hormone levels GO:0010817 211 0.116
cation homeostasis GO:0055080 212 0.115
negative regulation of t cell proliferation GO:0042130 38 0.115
regulation of homeostatic process GO:0032844 182 0.114
regulation of interleukin 18 production GO:0032661 3 0.113
negative regulation of apoptotic signaling pathway GO:2001234 104 0.113
Mouse
production of molecular mediator of immune response GO:0002440 103 0.113
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.112
regulation of kinase activity GO:0043549 249 0.112
positive regulation of lymphocyte activation GO:0051251 140 0.112
activation of mapk activity GO:0000187 59 0.112
positive regulation of hydrolase activity GO:0051345 148 0.111
Mouse
cellular lipid metabolic process GO:0044255 323 0.111
cellular ketone metabolic process GO:0042180 84 0.110
positive regulation of peptidase activity GO:0010952 49 0.109
Mouse
regulation of cytokine production GO:0001817 266 0.109
Mouse
epithelial cell proliferation GO:0050673 174 0.107
blood vessel morphogenesis GO:0048514 285 0.106
regulation of b cell mediated immunity GO:0002712 37 0.106
multicellular organismal homeostasis GO:0048871 164 0.106
defense response to other organism GO:0098542 197 0.105
Zebrafish Mouse
positive regulation of defense response GO:0031349 124 0.105
cellular response to dna damage stimulus GO:0006974 207 0.105
immune response activating signal transduction GO:0002757 116 0.104
response to amino acid GO:0043200 37 0.103
regulation of innate immune response GO:0045088 91 0.103
cellular amine metabolic process GO:0044106 44 0.103
regulation of cellular amino acid metabolic process GO:0006521 5 0.102
positive regulation of endopeptidase activity GO:0010950 43 0.100
Mouse
anion transport GO:0006820 177 0.100
adaptive immune response GO:0002250 155 0.099
response to acid chemical GO:0001101 111 0.099
b cell activation involved in immune response GO:0002312 50 0.099
negative regulation of hydrolase activity GO:0051346 71 0.098
Mouse
regulation of adaptive immune response GO:0002819 90 0.098
regulation of protein processing GO:0070613 96 0.098
Mouse
antibacterial peptide biosynthetic process GO:0002780 2 0.098
intracellular protein transport GO:0006886 204 0.097
positive regulation of secretion GO:0051047 130 0.097
organic anion transport GO:0015711 137 0.096
regulation of body fluid levels GO:0050878 162 0.096
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.096
growth of symbiont in host GO:0044117 23 0.096
Mouse
engulfment of apoptotic cell GO:0043652 3 0.096
regulation of inflammatory response GO:0050727 147 0.095
divalent inorganic cation homeostasis GO:0072507 138 0.095
positive regulation of b cell mediated immunity GO:0002714 26 0.095
regulation of establishment of protein localization GO:0070201 181 0.094
positive regulation of t cell activation GO:0050870 101 0.092
interleukin 6 production GO:0032635 58 0.092
Mouse
lymphocyte proliferation GO:0046651 164 0.091
antibacterial peptide production GO:0002778 2 0.090
regulation of cell adhesion GO:0030155 154 0.090
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.089
Mouse
regulation of interleukin 6 production GO:0032675 55 0.089
cellular homeostasis GO:0019725 240 0.088
positive regulation of apoptotic signaling pathway GO:2001235 95 0.088
Mouse
striated muscle tissue development GO:0014706 293 0.088
mapk cascade GO:0000165 281 0.088
gland development GO:0048732 330 0.088
peptidyl tyrosine modification GO:0018212 145 0.087
regulation of membrane potential GO:0042391 192 0.087
nitrogen compound transport GO:0071705 271 0.087
interferon gamma production GO:0032609 67 0.086
Mouse
regulation of cell activation GO:0050865 289 0.086
Mouse
cytokine secretion GO:0050663 72 0.086
cytoplasmic transport GO:0016482 234 0.086
metal ion homeostasis GO:0055065 189 0.086
myeloid leukocyte differentiation GO:0002573 119 0.086
inflammatory response GO:0006954 244 0.085
regulation of leukocyte proliferation GO:0070663 121 0.085
regulation of endopeptidase activity GO:0052548 89 0.085
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.085
regulation of prostaglandin endoperoxide synthase activity GO:0060584 2 0.084
regulation of cell cycle GO:0051726 281 0.084
positive regulation of mapk cascade GO:0043410 170 0.084
negative regulation of response to wounding GO:1903035 77 0.083
positive regulation of map kinase activity GO:0043406 84 0.083
phagocytosis GO:0006909 66 0.083
regulation of nucleocytoplasmic transport GO:0046822 73 0.083
transmembrane transport GO:0055085 412 0.083
regulation of t cell proliferation GO:0042129 92 0.083
regulation of leukocyte mediated immunity GO:0002703 104 0.082
epithelial tube morphogenesis GO:0060562 303 0.082
action potential GO:0001508 78 0.082
skeletal system development GO:0001501 356 0.082
negative regulation of immune system process GO:0002683 209 0.081
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 65 0.081
Mouse
protein kinase b signaling GO:0043491 74 0.081
humoral immune response mediated by circulating immunoglobulin GO:0002455 14 0.080
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.080
Mouse
positive regulation of behavior GO:0048520 40 0.080
leukocyte activation involved in immune response GO:0002366 126 0.079
regulation of antimicrobial humoral response GO:0002759 3 0.079
digestive system development GO:0055123 200 0.079
multicellular organismal signaling GO:0035637 91 0.079
positive regulation of cell activation GO:0050867 158 0.079
regulation of chronic inflammatory response to antigenic stimulus GO:0002874 3 0.078
Mouse
regulation of chemotaxis GO:0050920 53 0.077
intrinsic apoptotic signaling pathway GO:0097193 132 0.077
Mouse
neuron apoptotic process GO:0051402 142 0.077
oxidation reduction process GO:0055114 342 0.077
positive regulation of apoptotic process GO:0043065 217 0.076
Mouse
developmental maturation GO:0021700 193 0.076
muscle system process GO:0003012 141 0.075
negative regulation of adaptive immune response GO:0002820 25 0.075
regulation of myeloid leukocyte differentiation GO:0002761 58 0.074
amide transport GO:0042886 138 0.074
tumor necrosis factor mediated signaling pathway GO:0033209 13 0.074
response to oxidative stress GO:0006979 123 0.074
negative regulation of nik nf kappab signaling GO:1901223 2 0.073
antibacterial humoral response GO:0019731 8 0.071
regulation of cell motility GO:2000145 236 0.071
interleukin 10 secretion GO:0072608 4 0.071
hormone secretion GO:0046879 128 0.071
protein secretion GO:0009306 111 0.070
transmission of nerve impulse GO:0019226 76 0.070
t cell proliferation GO:0042098 120 0.070
cellular divalent inorganic cation homeostasis GO:0072503 127 0.070
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.068
negative regulation of homeostatic process GO:0032845 71 0.068
lymphocyte activation involved in immune response GO:0002285 93 0.068
positive regulation of nervous system development GO:0051962 221 0.067
positive regulation of cell development GO:0010720 237 0.067
nuclear transport GO:0051169 139 0.067
positive regulation of cell death GO:0010942 224 0.067
Mouse
stem cell differentiation GO:0048863 268 0.067
cellular response to acid chemical GO:0071229 68 0.066
lymphocyte migration GO:0072676 26 0.066
lipid localization GO:0010876 126 0.066
positive regulation of programmed cell death GO:0043068 218 0.065
Mouse
epidermis development GO:0008544 187 0.065
regulation of cell migration GO:0030334 219 0.065
t cell receptor signaling pathway GO:0050852 46 0.065
inflammatory response to antigenic stimulus GO:0002437 30 0.065
Mouse
negative regulation of inflammatory response GO:0050728 61 0.064
muscle cell differentiation GO:0042692 261 0.064
negative regulation of cellular protein metabolic process GO:0032269 247 0.064
Mouse
cellular response to external stimulus GO:0071496 88 0.064
defense response to bacterium GO:0042742 119 0.064
Zebrafish Mouse
morphogenesis of a branching structure GO:0001763 203 0.063
Mouse
t cell differentiation GO:0030217 174 0.063
cation transport GO:0006812 399 0.063
negative regulation of mapk cascade GO:0043409 65 0.063
cellular calcium ion homeostasis GO:0006874 119 0.063
hair cycle GO:0042633 90 0.063
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.063
placenta development GO:0001890 140 0.062
Mouse
tissue homeostasis GO:0001894 115 0.062
negative regulation of lymphocyte proliferation GO:0050672 45 0.062
homeostasis of number of cells GO:0048872 210 0.062
chronic inflammatory response to antigenic stimulus GO:0002439 3 0.061
Mouse
striated muscle cell development GO:0055002 125 0.061
b cell activation GO:0042113 161 0.061
dephosphorylation GO:0016311 129 0.061
positive regulation of transferase activity GO:0051347 167 0.061
positive regulation of ion transport GO:0043270 65 0.061
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.060
negative regulation of protein processing GO:0010955 79 0.060
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.060
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.060
Mouse
response to dsrna GO:0043331 30 0.060
amine metabolic process GO:0009308 45 0.059
antigen receptor mediated signaling pathway GO:0050851 64 0.059
stem cell development GO:0048864 219 0.059
negative regulation of phosphorus metabolic process GO:0010563 184 0.059
glucose transport GO:0015758 56 0.059
monosaccharide metabolic process GO:0005996 106 0.058
carbohydrate transport GO:0008643 62 0.058
digestive tract development GO:0048565 190 0.058
negative regulation of phosphorylation GO:0042326 166 0.058
positive regulation of kinase activity GO:0033674 155 0.058
spermatogenesis GO:0007283 284 0.058
positive regulation of cell migration GO:0030335 109 0.058
regulation of myeloid cell differentiation GO:0045637 96 0.057
cellular response to hormone stimulus GO:0032870 150 0.057
acute inflammatory response GO:0002526 41 0.057
regulation of protein localization GO:0032880 231 0.057
lipid transport GO:0006869 98 0.057
regulation of cellular catabolic process GO:0031329 242 0.056
male gamete generation GO:0048232 285 0.056
response to peptide GO:1901652 136 0.056
antimicrobial peptide production GO:0002775 2 0.055
regulation of cytokine production involved in immune response GO:0002718 26 0.055
protein import into nucleus GO:0006606 95 0.055
mammary gland epithelial cell proliferation GO:0033598 24 0.055
organonitrogen compound biosynthetic process GO:1901566 192 0.054
cellular amide metabolic process GO:0043603 58 0.054
regulation of glucose transport GO:0010827 32 0.054
defense response to gram positive bacterium GO:0050830 50 0.054
neuron death GO:0070997 154 0.054
cellular ion homeostasis GO:0006873 165 0.054
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.054
Mouse
response to organic cyclic compound GO:0014070 198 0.054
protein localization to organelle GO:0033365 185 0.054
positive regulation of leukocyte mediated immunity GO:0002705 70 0.054
negative regulation of defense response GO:0031348 77 0.054
regulation of production of molecular mediator of immune response GO:0002700 65 0.054
cellular response to molecule of bacterial origin GO:0071219 83 0.054
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.054
Mouse
anatomical structure homeostasis GO:0060249 145 0.054
defense response to virus GO:0051607 68 0.054
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.053
axonogenesis GO:0007409 274 0.053
negative regulation of cellular amine metabolic process GO:0033239 1 0.053
lymphocyte mediated immunity GO:0002449 139 0.053
positive regulation of cell motility GO:2000147 116 0.053
response to nutrient levels GO:0031667 109 0.052
interleukin 5 secretion GO:0072603 2 0.052
stress activated protein kinase signaling cascade GO:0031098 81 0.052
cellular response to extracellular stimulus GO:0031668 81 0.052
response to radiation GO:0009314 165 0.052
skin development GO:0043588 220 0.052
positive regulation of adaptive immune response GO:0002821 61 0.052
respiratory system development GO:0060541 190 0.051
regulation of interleukin 5 secretion GO:2000662 2 0.051
negative regulation of cytokine production GO:0001818 84 0.051
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.051
Mouse
peptidyl amino acid modification GO:0018193 336 0.051
regulation of leukocyte differentiation GO:1902105 159 0.051
leukocyte migration GO:0050900 124 0.051
cellular response to oxidative stress GO:0034599 76 0.051
appendage development GO:0048736 166 0.050
embryonic placenta development GO:0001892 98 0.050
Mouse
lymphocyte differentiation GO:0030098 242 0.050
muscle fiber development GO:0048747 76 0.050
response to organonitrogen compound GO:0010243 246 0.050
posttranscriptional regulation of gene expression GO:0010608 155 0.049
regulation of interleukin 13 secretion GO:2000665 2 0.049
cell fate commitment GO:0045165 210 0.049
cellular response to biotic stimulus GO:0071216 92 0.049
Mouse
positive regulation of osteoclast differentiation GO:0045672 15 0.049
cellular macromolecule catabolic process GO:0044265 206 0.049
lipid biosynthetic process GO:0008610 179 0.049
negative regulation of secretion GO:0051048 61 0.049
immune response regulating signaling pathway GO:0002764 125 0.048
regulation of protein targeting GO:1903533 61 0.048
nucleocytoplasmic transport GO:0006913 139 0.048
macromolecule catabolic process GO:0009057 281 0.048
regulation of peptide transport GO:0090087 91 0.047
myotube differentiation GO:0014902 105 0.047
regulation of intracellular transport GO:0032386 159 0.047
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.047
carbohydrate homeostasis GO:0033500 128 0.046
ear development GO:0043583 200 0.046
myelination GO:0042552 74 0.046
regulation of cellular ketone metabolic process GO:0010565 66 0.046
response to growth factor GO:0070848 198 0.046
regulation of osteoclast differentiation GO:0045670 36 0.046
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.046
regulation of metal ion transport GO:0010959 106 0.045
negative regulation of protein metabolic process GO:0051248 282 0.045
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.045
positive regulation of lymphocyte proliferation GO:0050671 70 0.045
cellular response to organonitrogen compound GO:0071417 145 0.045
single organism cell adhesion GO:0098602 156 0.045
regulation of neuron differentiation GO:0045664 281 0.045
positive regulation of secretion by cell GO:1903532 114 0.045
innate immune response GO:0045087 157 0.045
calcium ion transport GO:0006816 159 0.045
response to inorganic substance GO:0010035 96 0.045
divalent metal ion transport GO:0070838 172 0.044
sequestering of calcium ion GO:0051208 18 0.044
molting cycle GO:0042303 90 0.044
regulation of protein secretion GO:0050708 82 0.044
leukocyte apoptotic process GO:0071887 71 0.044
heart morphogenesis GO:0003007 178 0.044
negative regulation of intracellular signal transduction GO:1902532 167 0.043
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.043
glial cell differentiation GO:0010001 131 0.043
regulation of map kinase activity GO:0043405 120 0.043
membrane organization GO:0061024 245 0.043
regulation of lipid transport GO:0032368 36 0.043
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.043
Mouse
liver development GO:0001889 66 0.043
regulation of immunoglobulin mediated immune response GO:0002889 37 0.042
muscle tissue development GO:0060537 308 0.042
regulation of stress activated mapk cascade GO:0032872 69 0.042
calcium ion homeostasis GO:0055074 127 0.042
muscle cell development GO:0055001 133 0.042
regulation of translational initiation by iron GO:0006447 2 0.042
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.042
Mouse
stress activated mapk cascade GO:0051403 80 0.041
sensory organ morphogenesis GO:0090596 242 0.041
positive regulation of t cell proliferation GO:0042102 52 0.041
regulation of reactive oxygen species metabolic process GO:2000377 40 0.041
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.041
antimicrobial peptide biosynthetic process GO:0002777 2 0.041
gliogenesis GO:0042063 141 0.041
interspecies interaction between organisms GO:0044419 83 0.041
Mouse
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.041
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.041
hormone metabolic process GO:0042445 86 0.041
regulation of defense response to bacterium GO:1900424 3 0.041
skeletal muscle organ development GO:0060538 163 0.040
positive regulation of myeloid cell differentiation GO:0045639 43 0.040
regulation of tumor necrosis factor production GO:0032680 49 0.040
Mouse
monosaccharide transport GO:0015749 58 0.040
peptide metabolic process GO:0006518 46 0.040
regulation of dna recombination GO:0000018 34 0.040
sequestering of metal ion GO:0051238 19 0.040
lymphocyte homeostasis GO:0002260 64 0.040
protein catabolic process GO:0030163 221 0.039
temperature homeostasis GO:0001659 26 0.039
cell maturation GO:0048469 127 0.039
regulation of anatomical structure size GO:0090066 178 0.039
activation of innate immune response GO:0002218 56 0.039
regulation of jnk cascade GO:0046328 62 0.039
positive regulation of cytoplasmic transport GO:1903651 40 0.039
generation of precursor metabolites and energy GO:0006091 103 0.039
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.039
Mouse
extracellular matrix organization GO:0030198 147 0.039
oligodendrocyte differentiation GO:0048709 53 0.038
morphogenesis of a branching epithelium GO:0061138 193 0.038
Mouse
response to peptide hormone GO:0043434 127 0.038
regulation of peptide secretion GO:0002791 77 0.038
regulation of cytokine biosynthetic process GO:0042035 59 0.038
regulation of humoral immune response mediated by circulating immunoglobulin GO:0002923 10 0.038
intracellular receptor signaling pathway GO:0030522 74 0.038
positive regulation of protein secretion GO:0050714 52 0.038
angiogenesis GO:0001525 201 0.038
negative regulation of proteolysis GO:0045861 74 0.038
Mouse
cytosolic calcium ion homeostasis GO:0051480 70 0.037
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.037
negative regulation of t cell activation GO:0050868 65 0.037
regulation of peptide hormone secretion GO:0090276 75 0.037
digestive tract morphogenesis GO:0048546 147 0.037
negative regulation of lymphocyte activation GO:0051250 91 0.037
hexose transport GO:0008645 56 0.036
interleukin 1 production GO:0032612 31 0.036
regulation of lipid metabolic process GO:0019216 118 0.036
granulocyte chemotaxis GO:0071621 39 0.036
negative regulation of cell cycle GO:0045786 123 0.036
multicellular organism growth GO:0035264 161 0.036
protein targeting GO:0006605 143 0.036
peptide hormone secretion GO:0030072 109 0.036
myeloid dendritic cell activation GO:0001773 25 0.036
Mouse
heat generation GO:0031649 13 0.036
interleukin 18 production GO:0032621 4 0.036
positive regulation of jnk cascade GO:0046330 46 0.036
regulation of organ morphogenesis GO:2000027 144 0.035
establishment of protein localization to organelle GO:0072594 118 0.035
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
positive regulation of stress activated mapk cascade GO:0032874 48 0.035
negative regulation of peptidase activity GO:0010466 46 0.035
Mouse
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.035
hair follicle development GO:0001942 85 0.035
regulation of epithelial cell proliferation GO:0050678 141 0.035
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.034
positive regulation of leukocyte differentiation GO:1902107 86 0.034
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.034
ameboidal type cell migration GO:0001667 128 0.034
mitotic cell cycle process GO:1903047 159 0.034
positive regulation of protein transport GO:0051222 93 0.034
b cell mediated immunity GO:0019724 71 0.034
monocarboxylic acid metabolic process GO:0032787 191 0.034
positive regulation of antimicrobial peptide production GO:0002225 1 0.034
heterocycle catabolic process GO:0046700 280 0.034
ossification GO:0001503 216 0.033
mitochondrion organization GO:0007005 134 0.033
hexose metabolic process GO:0019318 98 0.033
peptide secretion GO:0002790 114 0.033
positive regulation of immune effector process GO:0002699 107 0.033
ion transmembrane transport GO:0034220 361 0.033
lung development GO:0030324 164 0.033
cellular metal ion homeostasis GO:0006875 151 0.033
neural tube development GO:0021915 160 0.033
positive regulation of intracellular protein transport GO:0090316 42 0.033
negative regulation of macrophage apoptotic process GO:2000110 3 0.033
positive regulation of intracellular transport GO:0032388 70 0.033
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.033
negative regulation of ossification GO:0030279 49 0.033
regulation of ion transmembrane transport GO:0034765 119 0.033
jnk cascade GO:0007254 72 0.033
wound healing GO:0042060 157 0.033
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.033
stem cell maintenance GO:0019827 130 0.033
glucose import GO:0046323 32 0.033
multi multicellular organism process GO:0044706 109 0.032
positive regulation of mitotic cell cycle GO:0045931 41 0.032
muscle contraction GO:0006936 101 0.032
regulation of wnt signaling pathway GO:0030111 123 0.032
regulation of action potential GO:0098900 4 0.032
glycerolipid metabolic process GO:0046486 122 0.031
response to light stimulus GO:0009416 135 0.031
positive regulation of protein kinase b signaling GO:0051897 32 0.031
regulation of protein kinase b signaling GO:0051896 56 0.031
forebrain development GO:0030900 302 0.031
regulation of lymphocyte differentiation GO:0045619 107 0.031
positive regulation of interleukin 2 production GO:0032743 19 0.031
respiratory tube development GO:0030323 167 0.031
single organismal cell cell adhesion GO:0016337 131 0.031
modification dependent protein catabolic process GO:0019941 133 0.030
positive regulation of homeostatic process GO:0032846 64 0.030
regulation of cytoplasmic transport GO:1903649 112 0.030
myeloid leukocyte activation GO:0002274 83 0.030
Mouse
tissue remodeling GO:0048771 102 0.030
single organism nuclear import GO:1902593 95 0.030
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.030
protein complex localization GO:0031503 19 0.030
positive regulation of response to wounding GO:1903036 66 0.030
regulation of cell cycle process GO:0010564 160 0.030
mitotic cell cycle GO:0000278 195 0.030
maintenance of location GO:0051235 89 0.030
regulation of antibacterial peptide production GO:0002786 1 0.029
leukocyte homeostasis GO:0001776 79 0.029
positive regulation of interleukin 6 production GO:0032755 37 0.029
response to extracellular stimulus GO:0009991 127 0.029
protein localization to nucleus GO:0034504 121 0.029
cell activation involved in immune response GO:0002263 126 0.029
response to oxygen levels GO:0070482 62 0.029
osteoclast differentiation GO:0030316 62 0.029
cerebral cortex development GO:0021987 86 0.029
insulin secretion GO:0030073 89 0.029
regulation of glucose import GO:0046324 26 0.029
cell chemotaxis GO:0060326 81 0.029
reactive nitrogen species metabolic process GO:2001057 0 0.029
fat soluble vitamin biosynthetic process GO:0042362 4 0.028
ras protein signal transduction GO:0007265 77 0.028
negative regulation of protein maturation GO:1903318 79 0.028
Mouse

Il22 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.150
disease of cellular proliferation DOID:14566 0 0.150
organ system cancer DOID:0050686 0 0.150
disease of anatomical entity DOID:7 0 0.059
nervous system disease DOID:863 0 0.059
central nervous system disease DOID:331 0 0.030