Mus musculus

0 known processes

Wac

WW domain containing adaptor with coiled-coil

(Aliases: A230035H12Rik,AI256735,AI256776,1110067P07Rik,Wwp4)

Wac biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.398
t cell activation GO:0042110 289 0.288
negative regulation of immune system process GO:0002683 209 0.170
cellular response to dna damage stimulus GO:0006974 207 0.147
Human
t cell differentiation GO:0030217 174 0.144
rhythmic process GO:0048511 174 0.111
rna splicing via transesterification reactions GO:0000375 43 0.101
regulation of hydrolase activity GO:0051336 246 0.093
olfactory learning GO:0008355 2 0.089
female gamete generation GO:0007292 74 0.087
leukocyte mediated immunity GO:0002443 174 0.085
negative regulation of phosphate metabolic process GO:0045936 184 0.083
germ cell development GO:0007281 185 0.082
oogenesis GO:0048477 56 0.081
negative regulation of cell activation GO:0050866 111 0.080
t cell proliferation GO:0042098 120 0.080
amine metabolic process GO:0009308 45 0.078
leukocyte differentiation GO:0002521 342 0.077
nuclear division GO:0000280 158 0.077
spermatogenesis GO:0007283 284 0.077
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.076
negative regulation of phosphorylation GO:0042326 166 0.075
mapk cascade GO:0000165 281 0.073
negative regulation of protein metabolic process GO:0051248 282 0.073
Human
stem cell differentiation GO:0048863 268 0.072
regulation of cellular response to stress GO:0080135 159 0.072
Human
negative regulation of molecular function GO:0044092 258 0.070
organelle fission GO:0048285 170 0.069
covalent chromatin modification GO:0016569 163 0.068
Human
positive regulation of protein modification process GO:0031401 299 0.067
oocyte axis specification GO:0007309 2 0.067
regulation of kinase activity GO:0043549 249 0.062
translation GO:0006412 93 0.060
regulation of cell activation GO:0050865 289 0.056
protein ubiquitination GO:0016567 171 0.056
Human
meiotic nuclear division GO:0007126 115 0.056
i kappab kinase nf kappab signaling GO:0007249 85 0.055
regulation of proteolysis GO:0030162 164 0.051
Human
regulation of mapk cascade GO:0043408 248 0.050
protein modification by small protein conjugation GO:0032446 187 0.047
Human
negative regulation of lymphocyte activation GO:0051250 91 0.047
regulation of cell cycle process GO:0010564 160 0.046
regulation of mrna processing GO:0050684 41 0.045
leukocyte proliferation GO:0070661 172 0.045
posttranscriptional regulation of gene expression GO:0010608 155 0.044
gene silencing GO:0016458 38 0.044
negative regulation of phosphorus metabolic process GO:0010563 184 0.043
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.043
Human
negative regulation of t cell activation GO:0050868 65 0.043
mitotic cell cycle GO:0000278 195 0.042
negative regulation of cellular protein metabolic process GO:0032269 247 0.042
Human
compound eye development GO:0048749 1 0.041
regulation of t cell activation GO:0050863 170 0.041
male gamete generation GO:0048232 285 0.039
mrna metabolic process GO:0016071 84 0.039
endocytosis GO:0006897 168 0.039
oocyte construction GO:0007308 2 0.039
microtubule based process GO:0007017 236 0.039
cognition GO:0050890 149 0.038
cellular amino acid metabolic process GO:0006520 103 0.038
negative regulation of mapk cascade GO:0043409 65 0.038
chemotaxis GO:0006935 247 0.037
lymphocyte proliferation GO:0046651 164 0.037
regulation of ras protein signal transduction GO:0046578 114 0.037
appendage development GO:0048736 166 0.037
regulation of organelle organization GO:0033043 289 0.035
pole plasm assembly GO:0007315 2 0.035
activation of immune response GO:0002253 138 0.035
rna splicing GO:0008380 54 0.035
organelle localization GO:0051640 179 0.034
modification dependent protein catabolic process GO:0019941 133 0.033
Human
immune effector process GO:0002252 321 0.033
negative regulation of cell proliferation GO:0008285 296 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.032
regulation of inflammatory response GO:0050727 147 0.032
regulation of cell cycle GO:0051726 281 0.031
multicellular organism growth GO:0035264 161 0.031
regulation of defense response GO:0031347 233 0.031
regulation of leukocyte mediated immunity GO:0002703 104 0.031
epithelial cell development GO:0002064 159 0.030
regulation of protein kinase activity GO:0045859 232 0.030
immune response activating signal transduction GO:0002757 116 0.030
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.029
spermatid development GO:0007286 108 0.029
regulation of t cell proliferation GO:0042129 92 0.029
small gtpase mediated signal transduction GO:0007264 97 0.029
regulation of vesicle mediated transport GO:0060627 139 0.029
mrna processing GO:0006397 63 0.028
cytoplasmic transport GO:0016482 234 0.028
muscle tissue development GO:0060537 308 0.028
rna processing GO:0006396 105 0.028
rho protein signal transduction GO:0007266 32 0.027
regulation of cellular amino acid metabolic process GO:0006521 5 0.026
digestive system development GO:0055123 200 0.026
protein modification by small protein conjugation or removal GO:0070647 207 0.026
Human
regulation of lymphocyte activation GO:0051249 240 0.026
negative regulation of protein phosphorylation GO:0001933 126 0.026
protein localization to organelle GO:0033365 185 0.025
aromatic compound catabolic process GO:0019439 286 0.025
regulation of system process GO:0044057 200 0.025
respiratory tube development GO:0030323 167 0.024
regulation of transferase activity GO:0051338 263 0.024
dna recombination GO:0006310 92 0.024
axon guidance GO:0007411 141 0.024
negative regulation of protein modification process GO:0031400 163 0.024
regulation of protein catabolic process GO:0042176 108 0.024
Human
regulation of body fluid levels GO:0050878 162 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.024
lung development GO:0030324 164 0.024
regulation of mitotic cell cycle phase transition GO:1901990 73 0.024
spermatid differentiation GO:0048515 115 0.023
transforming growth factor beta2 production GO:0032906 2 0.023
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.023
gonad development GO:0008406 141 0.023
peptidyl amino acid modification GO:0018193 336 0.023
regulation of cytoskeleton organization GO:0051493 122 0.022
positive regulation of mapk cascade GO:0043410 170 0.022
cell adhesion GO:0007155 329 0.022
placenta development GO:0001890 140 0.022
regulation of meiotic cell cycle GO:0051445 34 0.022
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.022
regulation of lymphocyte proliferation GO:0050670 117 0.021
development of primary sexual characteristics GO:0045137 143 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
ossification GO:0001503 216 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
learning or memory GO:0007611 148 0.021
homeostasis of number of cells GO:0048872 210 0.021
organic cyclic compound catabolic process GO:1901361 295 0.020
mitotic cell cycle process GO:1903047 159 0.020
positive regulation of organelle organization GO:0010638 128 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
stem cell development GO:0048864 219 0.020
regionalization GO:0003002 337 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
positive regulation of cellular catabolic process GO:0031331 148 0.019
Human
negative regulation of hydrolase activity GO:0051346 71 0.019
trna wobble base modification GO:0002097 2 0.019
actin cytoskeleton organization GO:0030036 220 0.019
intracellular protein transport GO:0006886 204 0.019
negative regulation of leukocyte proliferation GO:0070664 46 0.019
meiotic cell cycle GO:0051321 122 0.019
negative regulation of lymphocyte proliferation GO:0050672 45 0.019
regulation of cell migration GO:0030334 219 0.019
meiotic cell cycle process GO:1903046 77 0.019
negative regulation of transferase activity GO:0051348 85 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
dna replication GO:0006260 52 0.018
wnt signaling pathway GO:0016055 188 0.018
negative regulation of t cell proliferation GO:0042130 38 0.018
positive regulation of cell death GO:0010942 224 0.018
extrinsic apoptotic signaling pathway GO:0097191 126 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
mesenchyme development GO:0060485 152 0.018
cation transport GO:0006812 399 0.018
dna packaging GO:0006323 30 0.018
regulation of histone modification GO:0031056 56 0.017
lymphocyte homeostasis GO:0002260 64 0.017
regulation of innate immune response GO:0045088 91 0.017
regulation of ossification GO:0030278 112 0.017
positive regulation of growth GO:0045927 104 0.017
neuron projection guidance GO:0097485 141 0.017
myeloid cell homeostasis GO:0002262 114 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
Human
positive regulation of proteolysis GO:0045862 85 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
exocytosis GO:0006887 121 0.017
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
Human
t cell receptor signaling pathway GO:0050852 46 0.017
respiratory system development GO:0060541 190 0.017
regulation of protein stability GO:0031647 52 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.016
cell division GO:0051301 120 0.016
developmental maturation GO:0021700 193 0.016
canonical wnt signaling pathway GO:0060070 130 0.016
regulation of cytoplasmic transport GO:1903649 112 0.016
meiosis i GO:0007127 60 0.016
ribonucleoprotein complex subunit organization GO:0071826 28 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
regulation of jnk cascade GO:0046328 62 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
regulation of response to wounding GO:1903034 189 0.016
protein processing GO:0016485 163 0.016
Human
immune response regulating signaling pathway GO:0002764 125 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
protein catabolic process GO:0030163 221 0.015
Human
divalent metal ion transport GO:0070838 172 0.015
erk1 and erk2 cascade GO:0070371 77 0.015
chromatin silencing GO:0006342 15 0.015
oocyte anterior posterior axis specification GO:0007314 2 0.015
cellular ketone metabolic process GO:0042180 84 0.015
apoptotic signaling pathway GO:0097190 306 0.015
striated muscle tissue development GO:0014706 293 0.015
negative regulation of kinase activity GO:0033673 81 0.015
regulation of protein localization GO:0032880 231 0.015
circadian regulation of gene expression GO:0032922 48 0.015
regulation of chromosome organization GO:0033044 83 0.015
positive regulation of hydrolase activity GO:0051345 148 0.014
protein methylation GO:0006479 81 0.014
positive regulation of cellular protein catabolic process GO:1903364 34 0.014
chromosome segregation GO:0007059 48 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
axonogenesis GO:0007409 274 0.014
regulation of erk1 and erk2 cascade GO:0070372 71 0.014
body morphogenesis GO:0010171 45 0.014
mrna splicing via spliceosome GO:0000398 43 0.014
jak stat cascade GO:0007259 42 0.014
inter male aggressive behavior GO:0002121 3 0.014
positive regulation of transferase activity GO:0051347 167 0.014
cell maturation GO:0048469 127 0.014
intracellular mrna localization GO:0008298 4 0.014
innate immune response GO:0045087 157 0.013
cellular protein catabolic process GO:0044257 155 0.013
Human
microtubule cytoskeleton organization GO:0000226 157 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
granulocyte differentiation GO:0030851 17 0.013
organelle assembly GO:0070925 177 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.013
positive regulation of homeostatic process GO:0032846 64 0.013
ras protein signal transduction GO:0007265 77 0.013
regulation of intracellular transport GO:0032386 159 0.013
methylation GO:0032259 134 0.013
digestive tract development GO:0048565 190 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
myeloid leukocyte activation GO:0002274 83 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.013
genitalia development GO:0048806 37 0.013
regulation of mrna metabolic process GO:1903311 43 0.013
regulation of nucleoside metabolic process GO:0009118 130 0.013
multicellular organismal aging GO:0010259 24 0.013
blood circulation GO:0008015 195 0.013
antigen receptor mediated signaling pathway GO:0050851 64 0.013
regulation of binding GO:0051098 111 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.013
stem cell maintenance GO:0019827 130 0.012
cytokine production GO:0001816 319 0.012
protein targeting GO:0006605 143 0.012
uterus morphogenesis GO:0061038 2 0.012
erythrocyte differentiation GO:0030218 88 0.012
positive regulation of innate immune response GO:0045089 80 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
cellular amine metabolic process GO:0044106 44 0.012
regulation of protein complex assembly GO:0043254 83 0.012
carbohydrate homeostasis GO:0033500 128 0.012
negative regulation of adaptive immune response GO:0002820 25 0.012
angiogenesis GO:0001525 201 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
maternal determination of anterior posterior axis embryo GO:0008358 2 0.012
positive regulation of chromosome organization GO:2001252 33 0.012
regulation of secretion GO:0051046 274 0.012
positive regulation of protein catabolic process GO:0045732 60 0.012
embryonic appendage morphogenesis GO:0035113 126 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
leukocyte homeostasis GO:0001776 79 0.012
histone modification GO:0016570 159 0.012
Human
macromolecule catabolic process GO:0009057 281 0.012
Human
positive regulation of kinase activity GO:0033674 155 0.012
limb morphogenesis GO:0035108 149 0.012
cellular response to lipid GO:0071396 145 0.011
apical constriction GO:0003383 4 0.011
cell type specific apoptotic process GO:0097285 268 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
regulation of jak stat cascade GO:0046425 34 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.011
cellular homeostasis GO:0019725 240 0.011
chromatin organization GO:0006325 206 0.011
Human
phagocytosis GO:0006909 66 0.011
natural killer cell activation GO:0030101 44 0.011
learning GO:0007612 98 0.011
positive regulation of cell cycle GO:0045787 92 0.011
positive regulation of intracellular transport GO:0032388 70 0.011
response to lipopolysaccharide GO:0032496 128 0.011
nucleotide catabolic process GO:0009166 217 0.011
regulation of cellular ketone metabolic process GO:0010565 66 0.011
regulation of transcription by chromatin organization GO:0034401 0 0.011
nucleoside phosphate metabolic process GO:0006753 338 0.011
regulation of embryonic development GO:0045995 71 0.011
regulation of cytokine production GO:0001817 266 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
limb development GO:0060173 166 0.011
cellular response to abiotic stimulus GO:0071214 56 0.011
intracellular receptor signaling pathway GO:0030522 74 0.010
heart morphogenesis GO:0003007 178 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.010
regulation of endocytosis GO:0030100 69 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010
skeletal muscle organ development GO:0060538 163 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
stem cell fate specification GO:0048866 3 0.010
cell activation involved in immune response GO:0002263 126 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
appendage morphogenesis GO:0035107 149 0.010
heterocycle catabolic process GO:0046700 280 0.010

Wac disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
large intestine cancer DOID:5672 0 0.017
colon cancer DOID:219 0 0.017
gastrointestinal system cancer DOID:3119 0 0.017
intestinal cancer DOID:10155 0 0.017
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
colorectal cancer DOID:9256 0 0.017
disease of anatomical entity DOID:7 0 0.010
nervous system disease DOID:863 0 0.010