Mus musculus

0 known processes

Defa-rs1

defensin, alpha, related sequence 1

(Aliases: CRS1C,2010319H24Rik,CRS1C-2,Defcr-rs1,CRS1C-5,2010300L12Rik)

Defa-rs1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
antibacterial humoral response GO:0019731 8 0.512
Human Mouse
defense response to other organism GO:0098542 197 0.368
Human Mouse
defense response to bacterium GO:0042742 119 0.202
Human Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.164
regulation of cellular amino acid metabolic process GO:0006521 5 0.141
regulation of cellular amine metabolic process GO:0033238 20 0.117
humoral immune response GO:0006959 57 0.111
Human Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.096
Mouse
regulation of cytokine production GO:0001817 266 0.091
cellular amino acid metabolic process GO:0006520 103 0.089
amine metabolic process GO:0009308 45 0.079
immune response regulating signaling pathway GO:0002764 125 0.076
ion transmembrane transport GO:0034220 361 0.075
positive regulation of innate immune response GO:0045089 80 0.071
response to lipopolysaccharide GO:0032496 128 0.065
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.065
activation of immune response GO:0002253 138 0.062
regulation of innate immune response GO:0045088 91 0.061
negative regulation of immune system process GO:0002683 209 0.059
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.057
innate immune response GO:0045087 157 0.057
Human
defense response to gram negative bacterium GO:0050829 28 0.054
Mouse
regulation of protein transport GO:0051223 163 0.053
response to molecule of bacterial origin GO:0002237 143 0.053
Mouse
glycoprotein metabolic process GO:0009100 116 0.051
defense response to gram positive bacterium GO:0050830 50 0.051
Mouse
regulation of protein localization GO:0032880 231 0.051
macromolecule catabolic process GO:0009057 281 0.050
peptidyl amino acid modification GO:0018193 336 0.050
male gamete generation GO:0048232 285 0.048
cellular macromolecule catabolic process GO:0044265 206 0.046
regulation of cellular ketone metabolic process GO:0010565 66 0.045
skeletal system development GO:0001501 356 0.045
protein modification by small protein conjugation or removal GO:0070647 207 0.044
negative regulation of phosphorus metabolic process GO:0010563 184 0.042
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.041
regulation of establishment of protein localization GO:0070201 181 0.039
glycoprotein biosynthetic process GO:0009101 89 0.039
negative regulation of cell proliferation GO:0008285 296 0.036
reactive oxygen species metabolic process GO:0072593 84 0.036
epidermis development GO:0008544 187 0.035
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.035
regulation of membrane potential GO:0042391 192 0.035
response to organonitrogen compound GO:0010243 246 0.035
immune response activating signal transduction GO:0002757 116 0.035
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.033
spermatogenesis GO:0007283 284 0.033
inorganic cation transmembrane transport GO:0098662 207 0.033
negative regulation of cellular amine metabolic process GO:0033239 1 0.032
striated muscle tissue development GO:0014706 293 0.032
cytokine production GO:0001816 319 0.032
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.031
interspecies interaction between organisms GO:0044419 83 0.031
transmembrane transport GO:0055085 412 0.030
circulatory system process GO:0003013 197 0.030
skin development GO:0043588 220 0.030
cellular amine metabolic process GO:0044106 44 0.030
peptidyl serine modification GO:0018209 83 0.030
immune effector process GO:0002252 321 0.029
cartilage development GO:0051216 140 0.029
innate immune response activating signal transduction GO:0002758 50 0.029
negative regulation of cytokine production GO:0001818 84 0.029
positive regulation of protein phosphorylation GO:0001934 242 0.028
transmission of nerve impulse GO:0019226 76 0.028
positive regulation of protein modification process GO:0031401 299 0.028
regulation of cell migration GO:0030334 219 0.028
negative regulation of phosphorylation GO:0042326 166 0.027
protein modification by small protein conjugation GO:0032446 187 0.027
modification dependent macromolecule catabolic process GO:0043632 133 0.026
positive regulation of defense response GO:0031349 124 0.026
regulation of inflammatory response GO:0050727 147 0.026
neuronal action potential GO:0019228 54 0.026
regulation of proteolysis GO:0030162 164 0.026
cellular response to biotic stimulus GO:0071216 92 0.026
Mouse
carbohydrate metabolic process GO:0005975 230 0.025
protein ubiquitination GO:0016567 171 0.025
regulation of erk1 and erk2 cascade GO:0070372 71 0.025
cellular ketone metabolic process GO:0042180 84 0.025
protein catabolic process GO:0030163 221 0.025
antimicrobial humoral response GO:0019730 11 0.025
Human Mouse
activation of innate immune response GO:0002218 56 0.025
muscle cell differentiation GO:0042692 261 0.024
myeloid cell differentiation GO:0030099 233 0.024
cation transmembrane transport GO:0098655 266 0.023
multi multicellular organism process GO:0044706 109 0.023
gland development GO:0048732 330 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
modification dependent protein catabolic process GO:0019941 133 0.022
intracellular protein transport GO:0006886 204 0.022
inorganic ion transmembrane transport GO:0098660 234 0.022
mitotic cell cycle process GO:1903047 159 0.022
negative regulation of molecular function GO:0044092 258 0.022
cytoplasmic transport GO:0016482 234 0.022
protein maturation GO:0051604 176 0.021
positive regulation of keratinocyte proliferation GO:0010838 4 0.021
regulation of cell activation GO:0050865 289 0.021
cellular response to lipid GO:0071396 145 0.021
Mouse
homeostasis of number of cells GO:0048872 210 0.021
negative regulation of multi organism process GO:0043901 68 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
lymphocyte differentiation GO:0030098 242 0.021
toll like receptor signaling pathway GO:0002224 38 0.020
regulation of multi organism process GO:0043900 111 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
blood vessel morphogenesis GO:0048514 285 0.020
negative regulation of defense response GO:0031348 77 0.020
leukocyte migration GO:0050900 124 0.019
regulation of reactive oxygen species metabolic process GO:2000377 40 0.019
ossification GO:0001503 216 0.019
pattern recognition receptor signaling pathway GO:0002221 47 0.019
adult behavior GO:0030534 135 0.019
purine containing compound metabolic process GO:0072521 311 0.019
lung development GO:0030324 164 0.018
nucleobase containing small molecule metabolic process GO:0055086 352 0.018
regulation of defense response GO:0031347 233 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
positive regulation of cytokine production GO:0001819 174 0.018
cell recognition GO:0008037 83 0.018
multicellular organismal signaling GO:0035637 91 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
positive regulation of viral genome replication GO:0045070 2 0.018
negative regulation of keratinocyte differentiation GO:0045617 4 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
regulation of protein kinase activity GO:0045859 232 0.018
response to peptide GO:1901652 136 0.018
ubiquitin dependent protein catabolic process GO:0006511 129 0.018
regulation of system process GO:0044057 200 0.018
monosaccharide metabolic process GO:0005996 106 0.018
regulation of ion transport GO:0043269 215 0.017
regulation of response to wounding GO:1903034 189 0.017
t cell activation GO:0042110 289 0.017
viral life cycle GO:0019058 36 0.017
carboxylic acid transport GO:0046942 100 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
regulation of intracellular transport GO:0032386 159 0.017
proteasomal protein catabolic process GO:0010498 98 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
positive regulation of cell death GO:0010942 224 0.017
activation of mapk activity involved in innate immune response GO:0035419 2 0.016
regulation of nucleocytoplasmic transport GO:0046822 73 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
cellular protein catabolic process GO:0044257 155 0.016
regulation of organelle organization GO:0033043 289 0.016
sensory perception GO:0007600 245 0.016
cellular homeostasis GO:0019725 240 0.016
regulation of cell cycle GO:0051726 281 0.016
regulation of t cell differentiation GO:0045580 83 0.016
negative regulation of protein modification process GO:0031400 163 0.016
mitotic cell cycle GO:0000278 195 0.015
connective tissue development GO:0061448 179 0.015
leukocyte mediated immunity GO:0002443 174 0.015
negative regulation of nik nf kappab signaling GO:1901223 2 0.015
neural precursor cell proliferation GO:0061351 121 0.015
positive regulation of thymocyte migration GO:2000412 2 0.015
sulfur compound metabolic process GO:0006790 100 0.015
viral process GO:0016032 41 0.015
fertilization GO:0009566 127 0.015
regulation of transmembrane transport GO:0034762 128 0.015
camera type eye development GO:0043010 266 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
regulation of protein secretion GO:0050708 82 0.015
compound eye development GO:0048749 1 0.015
germ cell development GO:0007281 185 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
regulation of hydrolase activity GO:0051336 246 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
regulation of ion transmembrane transport GO:0034765 119 0.014
peptidyl serine phosphorylation GO:0018105 74 0.014
cellular protein complex assembly GO:0043623 116 0.014
action potential GO:0001508 78 0.014
proteoglycan metabolic process GO:0006029 38 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
central nervous system neuron differentiation GO:0021953 162 0.014
stem cell development GO:0048864 219 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
regionalization GO:0003002 337 0.014
negative regulation of immune effector process GO:0002698 55 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
cation transport GO:0006812 399 0.013
regulation of cell motility GO:2000145 236 0.013
regulation of transferase activity GO:0051338 263 0.013
positive regulation of proteolysis GO:0045862 85 0.013
apoptotic signaling pathway GO:0097190 306 0.013
regulation of mapk cascade GO:0043408 248 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
sensory perception of mechanical stimulus GO:0050954 107 0.013
regulation of map kinase activity GO:0043405 120 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
protein localization to organelle GO:0033365 185 0.013
bone development GO:0060348 120 0.013
protein processing GO:0016485 163 0.013
protein kinase b signaling GO:0043491 74 0.013
leukocyte differentiation GO:0002521 342 0.013
methylation GO:0032259 134 0.013
positive regulation of protein catabolic process GO:0045732 60 0.013
protein targeting GO:0006605 143 0.013
sulfur compound biosynthetic process GO:0044272 37 0.013
cellular response to abiotic stimulus GO:0071214 56 0.013
negative regulation of hydrolase activity GO:0051346 71 0.012
protein oligomerization GO:0051259 67 0.012
anatomical structure homeostasis GO:0060249 145 0.012
organelle localization GO:0051640 179 0.012
macromolecule methylation GO:0043414 120 0.012
interleukin 6 production GO:0032635 58 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
striated muscle contraction GO:0006941 45 0.012
regulation of leukocyte mediated immunity GO:0002703 104 0.012
protein glycosylation GO:0006486 55 0.012
actin polymerization or depolymerization GO:0008154 54 0.012
regulation of lymphocyte differentiation GO:0045619 107 0.012
regulation of wound healing GO:0061041 40 0.012
antibacterial peptide biosynthetic process GO:0002780 2 0.012
multicellular organism growth GO:0035264 161 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
interleukin 18 production GO:0032621 4 0.012
positive regulation of response to wounding GO:1903036 66 0.012
regulation of protein catabolic process GO:0042176 108 0.012
glucose metabolic process GO:0006006 92 0.012
skeletal system morphogenesis GO:0048705 203 0.012
epithelial cell proliferation GO:0050673 174 0.012
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.012
myeloid cell homeostasis GO:0002262 114 0.012
response to radiation GO:0009314 165 0.012
wound healing GO:0042060 157 0.012
lateral inhibition GO:0046331 1 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
sensory perception of sound GO:0007605 97 0.012
nucleotide metabolic process GO:0009117 332 0.012
myeloid leukocyte migration GO:0097529 57 0.012
myelination GO:0042552 74 0.011
nucleoside metabolic process GO:0009116 246 0.011
membrane organization GO:0061024 245 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
regulation of interleukin 6 production GO:0032675 55 0.011
antimicrobial peptide biosynthetic process GO:0002777 2 0.011
glycosylation GO:0070085 62 0.011
positive regulation of t cell activation GO:0050870 101 0.011
hindbrain development GO:0030902 128 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
ribose phosphate metabolic process GO:0019693 291 0.011
organelle fission GO:0048285 170 0.011
hexose metabolic process GO:0019318 98 0.011
regulation of protein kinase b signaling GO:0051896 56 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
neuron death GO:0070997 154 0.011
aromatic compound catabolic process GO:0019439 286 0.011
locomotory behavior GO:0007626 195 0.011
response to acid chemical GO:0001101 111 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
Mouse
ribonucleoside metabolic process GO:0009119 245 0.011
protein localization to nucleus GO:0034504 121 0.011
leukocyte chemotaxis GO:0030595 69 0.011
activation of mapk activity GO:0000187 59 0.011
angiogenesis GO:0001525 201 0.011
heterocycle catabolic process GO:0046700 280 0.011
regulation of viral transcription GO:0046782 3 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.011
regulation of response to biotic stimulus GO:0002831 38 0.011
negative regulation of leukocyte differentiation GO:1902106 51 0.011
chromatin organization GO:0006325 206 0.011
antimicrobial peptide production GO:0002775 2 0.011
positive regulation of cell migration GO:0030335 109 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
cell type specific apoptotic process GO:0097285 268 0.010
organonitrogen compound catabolic process GO:1901565 264 0.010
spermatid differentiation GO:0048515 115 0.010
positive regulation of cellular catabolic process GO:0031331 148 0.010
nucleoside phosphate catabolic process GO:1901292 222 0.010
macromolecule glycosylation GO:0043413 55 0.010
cell killing GO:0001906 67 0.010
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.010
tumor necrosis factor ligand superfamily member 11 production GO:0072535 1 0.010
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.010
regulation of t cell activation GO:0050863 170 0.010
muscle tissue development GO:0060537 308 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
ribonucleotide metabolic process GO:0009259 291 0.010
skeletal muscle organ development GO:0060538 163 0.010

Defa-rs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011