Mus musculus

26 known processes

Socs6

suppressor of cytokine signaling 6

(Aliases: SSI4,STAI4,Cish4,5830401B18Rik,AI447482,SOCS-6,Cis4,MGC102463,STATI4,1500012M23Rik,HSPC060,Socs4,SOCS-4)

Socs6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein ubiquitination GO:0016567 171 0.112
Mouse
cellular amine metabolic process GO:0044106 44 0.086
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.079
regulation of cellular ketone metabolic process GO:0010565 66 0.079
regulation of cellular amine metabolic process GO:0033238 20 0.078
regulation of protein kinase activity GO:0045859 232 0.061
Mouse
synaptic transmission GO:0007268 329 0.058
transmembrane transport GO:0055085 412 0.056
lymphocyte differentiation GO:0030098 242 0.054
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.054
regulation of cellular amino acid metabolic process GO:0006521 5 0.051
cellular ketone metabolic process GO:0042180 84 0.049
peptidyl amino acid modification GO:0018193 336 0.047
Mouse
protein modification by small protein conjugation GO:0032446 187 0.046
Mouse
synapse organization GO:0050808 125 0.044
ribonucleotide metabolic process GO:0009259 291 0.043
protein modification by small protein conjugation or removal GO:0070647 207 0.043
Mouse
regulation of cell activation GO:0050865 289 0.043
stem cell differentiation GO:0048863 268 0.040
t cell activation GO:0042110 289 0.040
ion transmembrane transport GO:0034220 361 0.038
leukocyte differentiation GO:0002521 342 0.038
Mouse
cellular amino acid metabolic process GO:0006520 103 0.038
cation transport GO:0006812 399 0.037
response to organonitrogen compound GO:0010243 246 0.037
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
regulation of cell motility GO:2000145 236 0.037
regulation of secretion GO:0051046 274 0.037
Mouse
chromatin organization GO:0006325 206 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.035
purine ribonucleotide metabolic process GO:0009150 290 0.034
regionalization GO:0003002 337 0.034
nucleotide metabolic process GO:0009117 332 0.034
cellular response to organonitrogen compound GO:0071417 145 0.034
Mouse
response to radiation GO:0009314 165 0.034
purine nucleotide metabolic process GO:0006163 302 0.033
amine metabolic process GO:0009308 45 0.033
organic cyclic compound catabolic process GO:1901361 295 0.033
establishment of vesicle localization GO:0051650 81 0.033
nucleoside triphosphate metabolic process GO:0009141 230 0.033
regulation of cell cycle GO:0051726 281 0.033
connective tissue development GO:0061448 179 0.032
regulation of mapk cascade GO:0043408 248 0.032
regulation of purine nucleotide metabolic process GO:1900542 169 0.032
positive regulation of kinase activity GO:0033674 155 0.032
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
negative regulation of cell proliferation GO:0008285 296 0.030
radial glia guided migration of purkinje cell GO:0021942 6 0.030
Mouse
multicellular organismal homeostasis GO:0048871 164 0.030
regulation of lymphocyte activation GO:0051249 240 0.030
cell fate commitment GO:0045165 210 0.029
nucleoside triphosphate catabolic process GO:0009143 205 0.029
cellular response to cytokine stimulus GO:0071345 189 0.029
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.029
Mouse
muscle cell differentiation GO:0042692 261 0.029
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.029
Mouse Fly
purine nucleoside triphosphate metabolic process GO:0009144 226 0.029
positive regulation of nervous system development GO:0051962 221 0.029
Mouse
multicellular organism growth GO:0035264 161 0.028
Mouse
neuron death GO:0070997 154 0.028
glycosyl compound metabolic process GO:1901657 246 0.028
nucleoside phosphate catabolic process GO:1901292 222 0.028
germ cell development GO:0007281 185 0.027
purine containing compound metabolic process GO:0072521 311 0.027
membrane organization GO:0061024 245 0.027
blood vessel morphogenesis GO:0048514 285 0.027
positive regulation of apoptotic process GO:0043065 217 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
action potential GO:0001508 78 0.027
response to oxidative stress GO:0006979 123 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
Mouse
neural precursor cell proliferation GO:0061351 121 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
hindbrain development GO:0030902 128 0.025
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.025
nucleoside metabolic process GO:0009116 246 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
cellular response to insulin stimulus GO:0032869 78 0.024
Mouse
mitotic cell cycle process GO:1903047 159 0.024
aromatic compound catabolic process GO:0019439 286 0.024
regulation of cell migration GO:0030334 219 0.023
inorganic cation transmembrane transport GO:0098662 207 0.023
regulation of neuron differentiation GO:0045664 281 0.023
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.023
cellular protein catabolic process GO:0044257 155 0.023
Human
mrna metabolic process GO:0016071 84 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
Mouse
cellular lipid metabolic process GO:0044255 323 0.023
maintenance of location GO:0051235 89 0.023
cell type specific apoptotic process GO:0097285 268 0.023
regulation of homeostatic process GO:0032844 182 0.022
chromatin modification GO:0016568 187 0.022
peptidyl tyrosine modification GO:0018212 145 0.022
Mouse
developmental maturation GO:0021700 193 0.022
cation transmembrane transport GO:0098655 266 0.022
regulation of transferase activity GO:0051338 263 0.022
Mouse
neurotransmitter secretion GO:0007269 62 0.022
cellular homeostasis GO:0019725 240 0.022
regulation of kinase activity GO:0043549 249 0.022
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.022
neuronal action potential GO:0019228 54 0.022
lateral inhibition GO:0046331 1 0.022
microtubule cytoskeleton organization GO:0000226 157 0.022
cellular divalent inorganic cation homeostasis GO:0072503 127 0.021
establishment of organelle localization GO:0051656 122 0.021
multicellular organismal signaling GO:0035637 91 0.021
positive regulation of cell death GO:0010942 224 0.021
organophosphate catabolic process GO:0046434 232 0.021
cellular calcium ion homeostasis GO:0006874 119 0.021
nucleotide catabolic process GO:0009166 217 0.021
divalent inorganic cation transport GO:0072511 178 0.021
purine containing compound catabolic process GO:0072523 213 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
regulation of secretion by cell GO:1903530 249 0.020
Mouse
adaptive immune response GO:0002250 155 0.020
Mouse
cytoplasmic transport GO:0016482 234 0.020
regulation of activation of jak2 kinase activity GO:0010534 1 0.020
Mouse
t cell differentiation GO:0030217 174 0.020
Mouse
regulation of system process GO:0044057 200 0.020
regulation of vesicle mediated transport GO:0060627 139 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
Mouse
mapk cascade GO:0000165 281 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
regulation of neurotransmitter levels GO:0001505 87 0.020
cellular chemical homeostasis GO:0055082 215 0.020
sensory perception GO:0007600 245 0.020
sensory organ morphogenesis GO:0090596 242 0.020
regulation of neuron apoptotic process GO:0043523 122 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.020
lipid biosynthetic process GO:0008610 179 0.019
morphogenesis of a branching epithelium GO:0061138 193 0.019
Mouse
defense response to other organism GO:0098542 197 0.019
positive regulation of protein modification process GO:0031401 299 0.019
Mouse
nitrogen compound transport GO:0071705 271 0.019
locomotory behavior GO:0007626 195 0.019
oocyte construction GO:0007308 2 0.019
epithelial tube morphogenesis GO:0060562 303 0.019
transmission of nerve impulse GO:0019226 76 0.019
regulation of ion transmembrane transport GO:0034765 119 0.019
peptidyl tyrosine phosphorylation GO:0018108 143 0.019
Mouse
regulation of insulin receptor signaling pathway GO:0046626 21 0.019
Mouse
positive regulation of cell development GO:0010720 237 0.019
Mouse
gliogenesis GO:0042063 141 0.019
stem cell maintenance GO:0019827 130 0.018
macromolecule catabolic process GO:0009057 281 0.018
Human
negative regulation of protein modification process GO:0031400 163 0.018
Mouse
calcium ion homeostasis GO:0055074 127 0.018
oxidation reduction process GO:0055114 342 0.018
ras protein signal transduction GO:0007265 77 0.018
skeletal system development GO:0001501 356 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
pallium development GO:0021543 120 0.018
Mouse
positive regulation of mapk cascade GO:0043410 170 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
ossification GO:0001503 216 0.018
regulation of inflammatory response GO:0050727 147 0.018
Mouse
neuron apoptotic process GO:0051402 142 0.018
regulation of cell projection organization GO:0031344 206 0.018
cyclic nucleotide metabolic process GO:0009187 59 0.017
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.017
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.017
actin cytoskeleton organization GO:0030036 220 0.017
cation homeostasis GO:0055080 212 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
Mouse
sequestering of metal ion GO:0051238 19 0.017
response to insulin GO:0032868 100 0.017
Mouse
methylation GO:0032259 134 0.017
female gamete generation GO:0007292 74 0.017
inorganic ion transmembrane transport GO:0098660 234 0.017
cell growth GO:0016049 130 0.017
mitotic cell cycle GO:0000278 195 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
response to growth factor GO:0070848 198 0.017
gland development GO:0048732 330 0.016
Mouse
divalent metal ion transport GO:0070838 172 0.016
positive regulation of transferase activity GO:0051347 167 0.016
Mouse
positive regulation of cell activation GO:0050867 158 0.016
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.016
learning or memory GO:0007611 148 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
forebrain development GO:0030900 302 0.016
Mouse
response to molecule of bacterial origin GO:0002237 143 0.016
cellular ion homeostasis GO:0006873 165 0.016
glycoprotein biosynthetic process GO:0009101 89 0.016
ribonucleoside monophosphate metabolic process GO:0009161 80 0.016
blood circulation GO:0008015 195 0.016
anatomical structure homeostasis GO:0060249 145 0.016
cognition GO:0050890 149 0.016
homeostasis of number of cells GO:0048872 210 0.016
telencephalon development GO:0021537 186 0.016
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.016
Mouse Fly
nuclear transport GO:0051169 139 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
spermatogenesis GO:0007283 284 0.015
positive regulation of leukocyte differentiation GO:1902107 86 0.015
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.015
lipid homeostasis GO:0055088 63 0.015
morphogenesis of a branching structure GO:0001763 203 0.015
Mouse
monocarboxylic acid metabolic process GO:0032787 191 0.015
myeloid leukocyte differentiation GO:0002573 119 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
renal system development GO:0072001 225 0.015
response to inorganic substance GO:0010035 96 0.015
cellular response to molecule of bacterial origin GO:0071219 83 0.015
protein localization to organelle GO:0033365 185 0.015
neurotransmitter transport GO:0006836 76 0.015
striated muscle tissue development GO:0014706 293 0.015
asymmetric stem cell division GO:0098722 3 0.015
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.015
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.015
inflammatory response GO:0006954 244 0.015
Mouse
sequestering of calcium ion GO:0051208 18 0.015
cell cycle switching GO:0060184 1 0.015
regulation of membrane potential GO:0042391 192 0.015
lipid localization GO:0010876 126 0.014
tissue homeostasis GO:0001894 115 0.014
cellularization GO:0007349 1 0.014
activation of adenylate cyclase activity GO:0007190 4 0.014
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.014
carbohydrate metabolic process GO:0005975 230 0.014
angiogenesis GO:0001525 201 0.014
negative regulation of immune system process GO:0002683 209 0.014
wound healing GO:0042060 157 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
negative regulation of neuron apoptotic process GO:0043524 92 0.014
tube formation GO:0035148 140 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
Mouse
organophosphate biosynthetic process GO:0090407 122 0.014
b cell activation GO:0042113 161 0.014
negative regulation of cell development GO:0010721 169 0.014
photoreceptor cell differentiation GO:0046530 52 0.014
nuclear division GO:0000280 158 0.014
calcium ion transport GO:0006816 159 0.014
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.014
fatty acid metabolic process GO:0006631 121 0.014
negative regulation of nervous system development GO:0051961 156 0.014
metal ion homeostasis GO:0055065 189 0.013
positive regulation of t cell differentiation GO:0045582 52 0.013
Mouse
organelle fission GO:0048285 170 0.013
male gamete generation GO:0048232 285 0.013
regulation of blood circulation GO:1903522 93 0.013
carbohydrate biosynthetic process GO:0016051 74 0.013
regulation of defense response GO:0031347 233 0.013
Mouse
cellular response to peptide hormone stimulus GO:0071375 92 0.013
Mouse
cellular response to biotic stimulus GO:0071216 92 0.013
cell division GO:0051301 120 0.013
circulatory system process GO:0003013 197 0.013
establishment or maintenance of cell polarity GO:0007163 86 0.013
endomembrane system organization GO:0010256 147 0.013
carbohydrate homeostasis GO:0033500 128 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
Human
response to lipopolysaccharide GO:0032496 128 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
regulation of ion transport GO:0043269 215 0.013
heterocycle catabolic process GO:0046700 280 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
intracellular protein transport GO:0006886 204 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
Mouse
purine nucleoside metabolic process GO:0042278 241 0.013
regulation of fibroblast proliferation GO:0048145 34 0.013
compound eye development GO:0048749 1 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
carbohydrate transport GO:0008643 62 0.013
chondrocyte development GO:0002063 24 0.013
cellular response to peptide GO:1901653 92 0.013
Mouse
glucose homeostasis GO:0042593 128 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
Mouse
embryonic epithelial tube formation GO:0001838 130 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
regulation of protein localization GO:0032880 231 0.012
Mouse
cartilage development GO:0051216 140 0.012
regulation of intracellular protein transport GO:0033157 82 0.012
regulation of anatomical structure size GO:0090066 178 0.012
response to organic cyclic compound GO:0014070 198 0.012
hindbrain radial glia guided cell migration GO:0021932 12 0.012
Mouse
glycosyl compound catabolic process GO:1901658 206 0.012
cellular protein complex assembly GO:0043623 116 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
organic anion transport GO:0015711 137 0.012
nucleoside catabolic process GO:0009164 206 0.012
camera type eye development GO:0043010 266 0.012
rhythmic process GO:0048511 174 0.012
exocytosis GO:0006887 121 0.012
chondrocyte hypertrophy GO:0003415 4 0.012
response to light stimulus GO:0009416 135 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
Mouse
myeloid cell differentiation GO:0030099 233 0.012
cellular response to acid chemical GO:0071229 68 0.012
Mouse
activation of immune response GO:0002253 138 0.012
response to extracellular stimulus GO:0009991 127 0.012
microtubule based process GO:0007017 236 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
negative regulation of cell activation GO:0050866 111 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
wnt signaling pathway GO:0016055 188 0.011
oocyte axis specification GO:0007309 2 0.011
protein targeting GO:0006605 143 0.011
covalent chromatin modification GO:0016569 163 0.011
bone morphogenesis GO:0060349 78 0.011
epithelial cell development GO:0002064 159 0.011
histone modification GO:0016570 159 0.011
negative regulation of molecular function GO:0044092 258 0.011
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
asymmetric neuroblast division GO:0055059 1 0.011
positive regulation of lymphocyte differentiation GO:0045621 61 0.011
Mouse
negative regulation of synapse assembly GO:0051964 3 0.011
neural tube development GO:0021915 160 0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.011
Mouse
axonogenesis GO:0007409 274 0.011
insulin receptor signaling pathway GO:0008286 49 0.011
Mouse
regulation of organelle organization GO:0033043 289 0.011
regulation of feeding behavior GO:0060259 3 0.011
regulation of t cell activation GO:0050863 170 0.011
immune response regulating signaling pathway GO:0002764 125 0.011
response to amino acid GO:0043200 37 0.011
Mouse
immune effector process GO:0002252 321 0.011
Mouse
negative regulation of cellular component organization GO:0051129 194 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
Mouse
meiotic cell cycle GO:0051321 122 0.011
bone development GO:0060348 120 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
peptide secretion GO:0002790 114 0.011
dephosphorylation GO:0016311 129 0.011
cytosolic calcium ion homeostasis GO:0051480 70 0.010
positive regulation of growth GO:0045927 104 0.010
glycoprotein metabolic process GO:0009100 116 0.010
regulation of neuron projection development GO:0010975 169 0.010
organelle localization GO:0051640 179 0.010
placenta development GO:0001890 140 0.010
Mouse
regulation of proteolysis GO:0030162 164 0.010
response to acid chemical GO:0001101 111 0.010
Mouse
regulation of transmembrane transport GO:0034762 128 0.010
regulation of protein transport GO:0051223 163 0.010
Mouse
positive regulation of programmed cell death GO:0043068 218 0.010

Socs6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.024
sensory system disease DOID:0050155 0 0.024
disease of anatomical entity DOID:7 0 0.024
eye and adnexa disease DOID:1492 0 0.024
nervous system disease DOID:863 0 0.024
eye disease DOID:5614 0 0.024
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.019
gastrointestinal system cancer DOID:3119 0 0.015
large intestine cancer DOID:5672 0 0.013
colon cancer DOID:219 0 0.013
intestinal cancer DOID:10155 0 0.013
colorectal cancer DOID:9256 0 0.013
retinal degeneration DOID:8466 0 0.011