Mus musculus

18 known processes

Dhrs4

dehydrogenase/reductase (SDR family) member 4

(Aliases: mouNRDR,NDRD,RRD,AI790593,AI043103,D14Ucla2,PHCR,CR,PSCD)

Dhrs4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.467
coenzyme metabolic process GO:0006732 52 0.403
small molecule catabolic process GO:0044282 71 0.346
carboxylic acid catabolic process GO:0046395 51 0.344
cofactor metabolic process GO:0051186 80 0.310
organic acid catabolic process GO:0016054 51 0.278
lipid oxidation GO:0034440 29 0.270
fatty acid oxidation GO:0019395 28 0.236
lipid catabolic process GO:0016042 69 0.231
fatty acid beta oxidation GO:0006635 16 0.201
cellular lipid metabolic process GO:0044255 323 0.188
cellular lipid catabolic process GO:0044242 52 0.179
fatty acid metabolic process GO:0006631 121 0.178
monocarboxylic acid catabolic process GO:0072329 27 0.163
monocarboxylic acid metabolic process GO:0032787 191 0.143
purine ribonucleoside metabolic process GO:0046128 241 0.137
sulfur compound metabolic process GO:0006790 100 0.129
fatty acid catabolic process GO:0009062 25 0.115
purine ribonucleotide metabolic process GO:0009150 290 0.113
lipid modification GO:0030258 65 0.105
acyl coa metabolic process GO:0006637 19 0.091
purine nucleoside metabolic process GO:0042278 241 0.085
nucleoside phosphate metabolic process GO:0006753 338 0.084
glycosyl compound metabolic process GO:1901657 246 0.079
ribonucleoside metabolic process GO:0009119 245 0.075
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.069
mitochondrial transport GO:0006839 36 0.068
purine nucleotide metabolic process GO:0006163 302 0.066
thioester metabolic process GO:0035383 19 0.065
purine containing compound metabolic process GO:0072521 311 0.062
organonitrogen compound biosynthetic process GO:1901566 192 0.062
nucleoside metabolic process GO:0009116 246 0.061
nucleobase containing small molecule metabolic process GO:0055086 352 0.057
mitochondrion organization GO:0007005 134 0.054
nucleoside monophosphate metabolic process GO:0009123 85 0.052
nucleoside triphosphate metabolic process GO:0009141 230 0.051
organic hydroxy compound metabolic process GO:1901615 203 0.051
Human
ribonucleoside monophosphate metabolic process GO:0009161 80 0.051
cellular ketone metabolic process GO:0042180 84 0.051
Human
ribonucleotide metabolic process GO:0009259 291 0.048
protein oligomerization GO:0051259 67 0.044
Human
cellular amino acid metabolic process GO:0006520 103 0.044
nucleotide metabolic process GO:0009117 332 0.041
ribonucleoside triphosphate metabolic process GO:0009199 220 0.039
purine nucleoside monophosphate metabolic process GO:0009126 81 0.039
membrane organization GO:0061024 245 0.039
regulation of cellular ketone metabolic process GO:0010565 66 0.038
small molecule biosynthetic process GO:0044283 132 0.038
purine deoxyribonucleoside triphosphate metabolic process GO:0009215 7 0.038
datp metabolic process GO:0046060 2 0.037
myeloid cell differentiation GO:0030099 233 0.036
response to organic cyclic compound GO:0014070 198 0.035
cofactor biosynthetic process GO:0051188 41 0.033
cellular amine metabolic process GO:0044106 44 0.032
deoxyribonucleoside triphosphate metabolic process GO:0009200 9 0.032
regulation of organelle organization GO:0033043 289 0.032
porphyrin containing compound metabolic process GO:0006778 22 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.031
amine metabolic process GO:0009308 45 0.031
leukocyte differentiation GO:0002521 342 0.031
tetrapyrrole metabolic process GO:0033013 22 0.031
transmembrane transport GO:0055085 412 0.030
atp metabolic process GO:0046034 75 0.029
regulation of cellular amino acid metabolic process GO:0006521 5 0.028
regulation of hormone levels GO:0010817 211 0.027
nucleoside phosphate biosynthetic process GO:1901293 79 0.027
ribose phosphate metabolic process GO:0019693 291 0.026
anion transport GO:0006820 177 0.025
apoptotic mitochondrial changes GO:0008637 48 0.024
ribonucleotide biosynthetic process GO:0009260 59 0.024
pigment biosynthetic process GO:0046148 26 0.024
heme biosynthetic process GO:0006783 12 0.024
gland development GO:0048732 330 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
ion transmembrane transport GO:0034220 361 0.023
lipid biosynthetic process GO:0008610 179 0.022
response to organonitrogen compound GO:0010243 246 0.022
organic cyclic compound catabolic process GO:1901361 295 0.022
adult behavior GO:0030534 135 0.021
epithelial cell development GO:0002064 159 0.021
nitrogen compound transport GO:0071705 271 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
cation transport GO:0006812 399 0.021
cellular respiration GO:0045333 38 0.021
very long chain fatty acid catabolic process GO:0042760 2 0.020
male gamete generation GO:0048232 285 0.020
generation of precursor metabolites and energy GO:0006091 103 0.020
iron sulfur cluster assembly GO:0016226 3 0.020
heme metabolic process GO:0042168 16 0.019
nucleoside catabolic process GO:0009164 206 0.019
porphyrin containing compound biosynthetic process GO:0006779 16 0.019
cytoplasmic transport GO:0016482 234 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.018
organophosphate biosynthetic process GO:0090407 122 0.018
apoptotic signaling pathway GO:0097190 306 0.018
response to nutrient levels GO:0031667 109 0.018
protein processing GO:0016485 163 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
response to oxidative stress GO:0006979 123 0.018
organic anion transport GO:0015711 137 0.018
response to growth factor GO:0070848 198 0.018
homeostasis of number of cells GO:0048872 210 0.017
response to oxygen levels GO:0070482 62 0.017
ribose phosphate biosynthetic process GO:0046390 59 0.017
cation transmembrane transport GO:0098655 266 0.017
regulation of mitochondrion organization GO:0010821 27 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
alpha amino acid metabolic process GO:1901605 59 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
gtp metabolic process GO:0046039 144 0.017
cellular homeostasis GO:0019725 240 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
guanosine containing compound metabolic process GO:1901068 144 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
sensory perception GO:0007600 245 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
aromatic compound catabolic process GO:0019439 286 0.016
regulation of cellular amine metabolic process GO:0033238 20 0.016
protein maturation GO:0051604 176 0.016
negative regulation of organelle organization GO:0010639 90 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
cellular ion homeostasis GO:0006873 165 0.016
maintenance of location GO:0051235 89 0.016
spermatogenesis GO:0007283 284 0.016
regulation of cell activation GO:0050865 289 0.016
lipid localization GO:0010876 126 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
purine nucleotide biosynthetic process GO:0006164 65 0.016
regulation of secretion by cell GO:1903530 249 0.016
deoxyribose phosphate metabolic process GO:0019692 9 0.015
alcohol metabolic process GO:0006066 116 0.015
Human
cellular metal ion homeostasis GO:0006875 151 0.015
heterocycle catabolic process GO:0046700 280 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
pigment metabolic process GO:0042440 32 0.015
amide transport GO:0042886 138 0.015
hormone metabolic process GO:0042445 86 0.015
cation homeostasis GO:0055080 212 0.015
regulation of secretion GO:0051046 274 0.015
positive regulation of protein modification process GO:0031401 299 0.015
positive regulation of transferase activity GO:0051347 167 0.015
regulation of protein localization GO:0032880 231 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
regulation of membrane potential GO:0042391 192 0.015
innate immune response GO:0045087 157 0.015
intracellular protein transport GO:0006886 204 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
divalent metal ion transport GO:0070838 172 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
cellular chemical homeostasis GO:0055082 215 0.014
cellular response to external stimulus GO:0071496 88 0.014
tetrapyrrole biosynthetic process GO:0033014 16 0.014
cell type specific apoptotic process GO:0097285 268 0.014
deoxyribonucleotide metabolic process GO:0009262 14 0.014
t cell activation GO:0042110 289 0.014
connective tissue development GO:0061448 179 0.014
purine containing compound biosynthetic process GO:0072522 70 0.014
response to starvation GO:0042594 65 0.014
endomembrane system organization GO:0010256 147 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
protein tetramerization GO:0051262 23 0.014
Human
coenzyme catabolic process GO:0009109 5 0.014
regulation of transferase activity GO:0051338 263 0.014
metal ion homeostasis GO:0055065 189 0.013
cellular amide metabolic process GO:0043603 58 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
cellular response to extracellular stimulus GO:0031668 81 0.013
negative regulation of immune system process GO:0002683 209 0.013
nucleotide biosynthetic process GO:0009165 78 0.013
liver development GO:0001889 66 0.013
pteridine containing compound metabolic process GO:0042558 5 0.013
multicellular organism growth GO:0035264 161 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
peptide secretion GO:0002790 114 0.013
purine containing compound catabolic process GO:0072523 213 0.013
plasma membrane organization GO:0007009 90 0.012
regulation of neuron differentiation GO:0045664 281 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
protein homooligomerization GO:0051260 43 0.012
spermatid differentiation GO:0048515 115 0.012
protein targeting GO:0006605 143 0.012
cellular protein complex assembly GO:0043623 116 0.012
defense response to other organism GO:0098542 197 0.012
peptide metabolic process GO:0006518 46 0.012
renal system development GO:0072001 225 0.012
hepaticobiliary system development GO:0061008 67 0.012
forebrain development GO:0030900 302 0.012
nucleotide catabolic process GO:0009166 217 0.012
divalent inorganic cation transport GO:0072511 178 0.012
regulation of vacuole organization GO:0044088 4 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
locomotory behavior GO:0007626 195 0.012
transition metal ion transport GO:0000041 38 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
multicellular organismal signaling GO:0035637 91 0.011
response to epidermal growth factor GO:0070849 4 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
cellular response to lipid GO:0071396 145 0.011
skeletal system development GO:0001501 356 0.011
skin development GO:0043588 220 0.011
embryonic epithelial tube formation GO:0001838 130 0.011
inflammatory response GO:0006954 244 0.011
germ cell development GO:0007281 185 0.011
energy derivation by oxidation of organic compounds GO:0015980 77 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
dna metabolic process GO:0006259 303 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
positive regulation of cell development GO:0010720 237 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
dephosphorylation GO:0016311 129 0.011
negative regulation of molecular function GO:0044092 258 0.011
t cell proliferation GO:0042098 120 0.011
urogenital system development GO:0001655 261 0.011
regulation of mapk cascade GO:0043408 248 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
transmission of nerve impulse GO:0019226 76 0.011
male gonad development GO:0008584 88 0.011
protein localization to organelle GO:0033365 185 0.011
nucleoside biosynthetic process GO:0009163 21 0.011
purine ribonucleotide biosynthetic process GO:0009152 59 0.011
regulation of kinase activity GO:0043549 249 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
positive regulation of kinase activity GO:0033674 155 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
serotonin metabolic process GO:0042428 8 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
glycosyl compound catabolic process GO:1901658 206 0.010
cellular modified amino acid metabolic process GO:0006575 63 0.010
protein localization to membrane GO:0072657 108 0.010
defense response to bacterium GO:0042742 119 0.010
gonad development GO:0008406 141 0.010
kidney development GO:0001822 213 0.010
establishment of protein localization to organelle GO:0072594 118 0.010
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
very long chain fatty acid metabolic process GO:0000038 8 0.010
anatomical structure homeostasis GO:0060249 145 0.010
organic hydroxy compound transport GO:0015850 93 0.010
organic acid biosynthetic process GO:0016053 86 0.010
regulation of homeostatic process GO:0032844 182 0.010
posttranscriptional regulation of gene expression GO:0010608 155 0.010
epithelial tube morphogenesis GO:0060562 303 0.010
tissue homeostasis GO:0001894 115 0.010
gtp catabolic process GO:0006184 143 0.010
response to peptide hormone GO:0043434 127 0.010
positive regulation of growth GO:0045927 104 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
mitochondrial protein processing GO:0034982 5 0.010

Dhrs4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.135
inherited metabolic disorder DOID:655 0 0.135
disease of cellular proliferation DOID:14566 0 0.033
cancer DOID:162 0 0.029
organ system cancer DOID:0050686 0 0.015
disease of anatomical entity DOID:7 0 0.010
nervous system disease DOID:863 0 0.010