Mus musculus

0 known processes

Nucb2

nucleobindin 2

(Aliases: Calnuc,AI607786,nesfatin-1,Nefa)

Nucb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytokine production GO:0001816 319 0.112
regulation of cellular amine metabolic process GO:0033238 20 0.078
amine metabolic process GO:0009308 45 0.068
transmembrane transport GO:0055085 412 0.064
cellular amine metabolic process GO:0044106 44 0.063
cation transport GO:0006812 399 0.057
mapk cascade GO:0000165 281 0.055
immune effector process GO:0002252 321 0.051
cellular ketone metabolic process GO:0042180 84 0.049
regulation of secretion by cell GO:1903530 249 0.049
apoptotic signaling pathway GO:0097190 306 0.045
regulation of cellular amino acid metabolic process GO:0006521 5 0.045
regulation of secretion GO:0051046 274 0.045
regulation of cellular ketone metabolic process GO:0010565 66 0.044
membrane organization GO:0061024 245 0.043
ion transmembrane transport GO:0034220 361 0.043
positive regulation of apoptotic process GO:0043065 217 0.042
cellular amino acid metabolic process GO:0006520 103 0.042
negative regulation of molecular function GO:0044092 258 0.041
exocytosis GO:0006887 121 0.040
regulation of cytokine production GO:0001817 266 0.040
spermatogenesis GO:0007283 284 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
ceramide biosynthetic process GO:0046513 20 0.037
cytoplasmic transport GO:0016482 234 0.036
lipid transport GO:0006869 98 0.036
regulation of organelle organization GO:0033043 289 0.035
divalent metal ion transport GO:0070838 172 0.034
maintenance of location GO:0051235 89 0.034
peptidyl amino acid modification GO:0018193 336 0.033
response to acid chemical GO:0001101 111 0.033
nucleotide metabolic process GO:0009117 332 0.032
carbohydrate metabolic process GO:0005975 230 0.032
regulation of mapk cascade GO:0043408 248 0.032
positive regulation of programmed cell death GO:0043068 218 0.032
regulation of transferase activity GO:0051338 263 0.032
glycosyl compound metabolic process GO:1901657 246 0.031
cellular lipid metabolic process GO:0044255 323 0.031
nucleobase containing small molecule metabolic process GO:0055086 352 0.031
lipid biosynthetic process GO:0008610 179 0.031
vesicle localization GO:0051648 86 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
organic hydroxy compound metabolic process GO:1901615 203 0.031
response to growth factor GO:0070848 198 0.030
male gamete generation GO:0048232 285 0.030
cell type specific apoptotic process GO:0097285 268 0.028
regulation of hydrolase activity GO:0051336 246 0.028
nitrogen compound transport GO:0071705 271 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
cellular chemical homeostasis GO:0055082 215 0.028
regulation of membrane potential GO:0042391 192 0.028
heterocycle catabolic process GO:0046700 280 0.027
aromatic compound catabolic process GO:0019439 286 0.027
anion transport GO:0006820 177 0.027
leukocyte differentiation GO:0002521 342 0.027
inflammatory response GO:0006954 244 0.027
cation homeostasis GO:0055080 212 0.027
cellular ion homeostasis GO:0006873 165 0.026
nucleotide catabolic process GO:0009166 217 0.026
lymphocyte differentiation GO:0030098 242 0.026
organelle localization GO:0051640 179 0.026
purine nucleoside metabolic process GO:0042278 241 0.026
striated muscle tissue development GO:0014706 293 0.026
compound eye development GO:0048749 1 0.026
negative regulation of phosphate metabolic process GO:0045936 184 0.025
muscle contraction GO:0006936 101 0.025
positive regulation of protein modification process GO:0031401 299 0.025
positive regulation of cell death GO:0010942 224 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
muscle tissue development GO:0060537 308 0.024
glycoprotein metabolic process GO:0009100 116 0.024
metal ion homeostasis GO:0055065 189 0.024
response to organic cyclic compound GO:0014070 198 0.024
purine ribonucleoside catabolic process GO:0046130 205 0.024
positive regulation of secretion GO:0051047 130 0.023
intracellular protein transport GO:0006886 204 0.023
sequestering of calcium ion GO:0051208 18 0.023
regulation of protein localization GO:0032880 231 0.023
skin development GO:0043588 220 0.022
establishment of vesicle localization GO:0051650 81 0.022
regulation of cell projection organization GO:0031344 206 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.022
wound healing GO:0042060 157 0.022
regulation of wnt signaling pathway GO:0030111 123 0.022
positive regulation of organelle organization GO:0010638 128 0.022
regulation of vesicle mediated transport GO:0060627 139 0.022
inorganic ion transmembrane transport GO:0098660 234 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
g protein coupled receptor signaling pathway GO:0007186 243 0.021
alcohol metabolic process GO:0006066 116 0.021
regulation of cell motility GO:2000145 236 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
cell activation involved in immune response GO:0002263 126 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
regulation of t cell activation GO:0050863 170 0.021
protein secretion GO:0009306 111 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
muscle system process GO:0003012 141 0.021
negative regulation of phosphorylation GO:0042326 166 0.020
cellular homeostasis GO:0019725 240 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
intrinsic apoptotic signaling pathway GO:0097193 132 0.020
leukocyte mediated immunity GO:0002443 174 0.020
homeostasis of number of cells GO:0048872 210 0.020
regulation of cell cycle GO:0051726 281 0.020
t cell activation GO:0042110 289 0.020
cell adhesion GO:0007155 329 0.020
endocytosis GO:0006897 168 0.020
purine containing compound metabolic process GO:0072521 311 0.020
camera type eye development GO:0043010 266 0.020
divalent inorganic cation transport GO:0072511 178 0.020
regulation of protein kinase activity GO:0045859 232 0.020
purine ribonucleotide metabolic process GO:0009150 290 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
purine containing compound catabolic process GO:0072523 213 0.019
response to lipopolysaccharide GO:0032496 128 0.019
cation transmembrane transport GO:0098655 266 0.019
cilium assembly GO:0042384 81 0.019
regulation of homeostatic process GO:0032844 182 0.019
positive regulation of cytokine production GO:0001819 174 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
cellular amide metabolic process GO:0043603 58 0.019
regulation of inflammatory response GO:0050727 147 0.019
sequestering of metal ion GO:0051238 19 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
regulation of multi organism process GO:0043900 111 0.019
response to organonitrogen compound GO:0010243 246 0.019
negative regulation of cytokine production GO:0001818 84 0.019
regulation of cell migration GO:0030334 219 0.018
calcium ion homeostasis GO:0055074 127 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
nucleoside catabolic process GO:0009164 206 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
sphingosine metabolic process GO:0006670 4 0.018
regulation of cell activation GO:0050865 289 0.018
carboxylic acid transport GO:0046942 100 0.018
peptide metabolic process GO:0006518 46 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.018
organic anion transport GO:0015711 137 0.018
urogenital system development GO:0001655 261 0.018
protein processing GO:0016485 163 0.018
organophosphate catabolic process GO:0046434 232 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
ribose phosphate metabolic process GO:0019693 291 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
regulation of hormone levels GO:0010817 211 0.017
endomembrane system organization GO:0010256 147 0.017
protein localization to organelle GO:0033365 185 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
interleukin 6 production GO:0032635 58 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
regulation of interleukin 6 production GO:0032675 55 0.017
ribonucleoside monophosphate metabolic process GO:0009161 80 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
macromolecule catabolic process GO:0009057 281 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
respiratory system development GO:0060541 190 0.017
circulatory system process GO:0003013 197 0.017
organic hydroxy compound biosynthetic process GO:1901617 77 0.017
gland development GO:0048732 330 0.017
small molecule biosynthetic process GO:0044283 132 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
lipid localization GO:0010876 126 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
cellular metal ion homeostasis GO:0006875 151 0.016
wnt signaling pathway GO:0016055 188 0.016
respiratory tube development GO:0030323 167 0.016
sensory perception GO:0007600 245 0.016
retrograde transport endosome to golgi GO:0042147 2 0.016
skeletal system development GO:0001501 356 0.016
cellular response to lipid GO:0071396 145 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
fat cell differentiation GO:0045444 160 0.016
regulation of protein transport GO:0051223 163 0.016
organelle assembly GO:0070925 177 0.016
positive regulation of secretion by cell GO:1903532 114 0.016
fertilization GO:0009566 127 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
blood coagulation GO:0007596 76 0.016
protein maturation GO:0051604 176 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
regulation of system process GO:0044057 200 0.016
lateral inhibition GO:0046331 1 0.016
amide transport GO:0042886 138 0.016
positive regulation of myeloid cell apoptotic process GO:0033034 4 0.016
regulation of kinase activity GO:0043549 249 0.016
regulation of protein secretion GO:0050708 82 0.016
t cell differentiation GO:0030217 174 0.016
regulation of ion transport GO:0043269 215 0.016
establishment of organelle localization GO:0051656 122 0.016
canonical wnt signaling pathway GO:0060070 130 0.016
positive regulation of hydrolase activity GO:0051345 148 0.016
synaptic transmission GO:0007268 329 0.015
coagulation GO:0050817 78 0.015
renal system development GO:0072001 225 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.015
negative regulation of protein modification process GO:0031400 163 0.015
regulation of adrenergic receptor signaling pathway GO:0071877 4 0.015
glycosyl compound catabolic process GO:1901658 206 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.015
inter male aggressive behavior GO:0002121 3 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
regionalization GO:0003002 337 0.015
vesicle organization GO:0016050 60 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
interleukin 8 production GO:0032637 4 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
neuron death GO:0070997 154 0.015
hemostasis GO:0007599 78 0.015
rho protein signal transduction GO:0007266 32 0.015
multicellular organismal signaling GO:0035637 91 0.015
epidermis development GO:0008544 187 0.015
calcium ion transport GO:0006816 159 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
angiogenesis GO:0001525 201 0.014
regulation of body fluid levels GO:0050878 162 0.014
regulation of neuron projection development GO:0010975 169 0.014
action potential GO:0001508 78 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
interleukin 8 secretion GO:0072606 3 0.014
regulation of muscle system process GO:0090257 80 0.014
nucleoside monophosphate metabolic process GO:0009123 85 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
lymphocyte proliferation GO:0046651 164 0.014
cognition GO:0050890 149 0.014
regulation of reproductive process GO:2000241 66 0.014
regulation of defense response GO:0031347 233 0.014
peptidyl tyrosine modification GO:0018212 145 0.014
blood circulation GO:0008015 195 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
regulation of circadian sleep wake cycle GO:0042749 3 0.014
skeletal muscle organ development GO:0060538 163 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.014
cardiac muscle contraction GO:0060048 32 0.014
transmission of nerve impulse GO:0019226 76 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
cellular protein complex assembly GO:0043623 116 0.014
forebrain development GO:0030900 302 0.013
regulation of neuron death GO:1901214 134 0.013
regulation of transmembrane transport GO:0034762 128 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
oxidation reduction process GO:0055114 342 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
adult behavior GO:0030534 135 0.013
ras protein signal transduction GO:0007265 77 0.013
kidney development GO:0001822 213 0.013
muscle cell differentiation GO:0042692 261 0.013
regulation of neuron differentiation GO:0045664 281 0.013
regulation of interleukin 8 production GO:0032677 3 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
myeloid leukocyte activation GO:0002274 83 0.013
response to radiation GO:0009314 165 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
regulation of cell adhesion GO:0030155 154 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
membrane lipid biosynthetic process GO:0046467 32 0.013
positive regulation of nervous system development GO:0051962 221 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
epithelial cell proliferation GO:0050673 174 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
positive regulation of cell motility GO:2000147 116 0.013
activation of immune response GO:0002253 138 0.013
actin cytoskeleton organization GO:0030036 220 0.013
neurotransmitter secretion GO:0007269 62 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
peptide transport GO:0015833 133 0.012
dna metabolic process GO:0006259 303 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
regulation of interleukin 8 secretion GO:2000482 2 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
ossification GO:0001503 216 0.012
positive regulation of cell development GO:0010720 237 0.012
regulation of response to wounding GO:1903034 189 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
adaptive immune response GO:0002250 155 0.012
single organism cell adhesion GO:0098602 156 0.012
positive regulation of protein transport GO:0051222 93 0.012
monocarboxylic acid transport GO:0015718 44 0.012
detection of stimulus GO:0051606 84 0.012
positive regulation of transferase activity GO:0051347 167 0.012
regulation of cellular response to stress GO:0080135 159 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
response to extracellular stimulus GO:0009991 127 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
locomotory behavior GO:0007626 195 0.012
spermatid differentiation GO:0048515 115 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
defense response to bacterium GO:0042742 119 0.012
response to inorganic substance GO:0010035 96 0.012
tissue remodeling GO:0048771 102 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
leukocyte proliferation GO:0070661 172 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
b cell activation GO:0042113 161 0.011
cell substrate adhesion GO:0031589 130 0.011
multi multicellular organism process GO:0044706 109 0.011
regulation of synaptic plasticity GO:0048167 87 0.011
hormone secretion GO:0046879 128 0.011
negative regulation of immune system process GO:0002683 209 0.011
organic hydroxy compound transport GO:0015850 93 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
germ cell development GO:0007281 185 0.011
regulation of neurotransmitter levels GO:0001505 87 0.011
developmental maturation GO:0021700 193 0.011
negative regulation of transferase activity GO:0051348 85 0.011
digestive tract development GO:0048565 190 0.011
positive regulation of cell adhesion GO:0045785 80 0.011
negative regulation of hydrolase activity GO:0051346 71 0.011
response to nutrient levels GO:0031667 109 0.011
blood vessel morphogenesis GO:0048514 285 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
innate immune response GO:0045087 157 0.011
neural tube development GO:0021915 160 0.011
phospholipid metabolic process GO:0006644 87 0.011
leukocyte homeostasis GO:0001776 79 0.011
regulation of blood pressure GO:0008217 93 0.011
neuronal action potential GO:0019228 54 0.011
mitotic cell cycle GO:0000278 195 0.011
protein targeting GO:0006605 143 0.011
adult locomotory behavior GO:0008344 91 0.011
retina development in camera type eye GO:0060041 119 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
glucose homeostasis GO:0042593 128 0.010
regulation of binding GO:0051098 111 0.010
regulation of metal ion transport GO:0010959 106 0.010
carbohydrate homeostasis GO:0033500 128 0.010
response to light stimulus GO:0009416 135 0.010
regulation of exocytosis GO:0017157 61 0.010
lung development GO:0030324 164 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
positive regulation of cellular catabolic process GO:0031331 148 0.010
muscle adaptation GO:0043500 39 0.010
development of primary male sexual characteristics GO:0046546 88 0.010
regulation of vacuole organization GO:0044088 4 0.010
learning or memory GO:0007611 148 0.010
negative regulation of mapk cascade GO:0043409 65 0.010
anatomical structure homeostasis GO:0060249 145 0.010
regulation of actin filament based process GO:0032970 99 0.010
regulation of angiogenesis GO:0045765 81 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
spermatid development GO:0007286 108 0.010
regulation of ossification GO:0030278 112 0.010
organic acid transport GO:0015849 101 0.010
chemotaxis GO:0006935 247 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
negative regulation of nervous system development GO:0051961 156 0.010
single organismal cell cell adhesion GO:0016337 131 0.010
embryonic organ morphogenesis GO:0048562 276 0.010
organism emergence from protective structure GO:0071684 4 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
tumor necrosis factor production GO:0032640 50 0.010

Nucb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.036
disease of anatomical entity DOID:7 0 0.036
disease of metabolism DOID:0014667 0 0.029
inherited metabolic disorder DOID:655 0 0.029
connective tissue disease DOID:65 0 0.016
musculoskeletal system disease DOID:17 0 0.016
bone disease DOID:0080001 0 0.016
sensory system disease DOID:0050155 0 0.013
eye disease DOID:5614 0 0.013
eye and adnexa disease DOID:1492 0 0.013
bone development disease DOID:0080006 0 0.010
lysosomal storage disease DOID:3211 0 0.010
retinal disease DOID:5679 0 0.010
retinal degeneration DOID:8466 0 0.010