Mus musculus

5 known processes

Ldhb

lactate dehydrogenase B

(Aliases: Ldh-2,H-Ldh,AI790582,Ldh2)

Ldhb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purine ribonucleotide metabolic process GO:0009150 290 0.174
cellular amino acid metabolic process GO:0006520 103 0.144
ribonucleotide metabolic process GO:0009259 291 0.123
nucleobase containing small molecule metabolic process GO:0055086 352 0.121
Rat
transmembrane transport GO:0055085 412 0.111
purine nucleotide metabolic process GO:0006163 302 0.111
nucleotide metabolic process GO:0009117 332 0.104
Rat
nucleoside phosphate metabolic process GO:0006753 338 0.101
Rat
purine nucleoside metabolic process GO:0042278 241 0.101
cellular amine metabolic process GO:0044106 44 0.101
purine containing compound metabolic process GO:0072521 311 0.098
cation transmembrane transport GO:0098655 266 0.088
amine metabolic process GO:0009308 45 0.086
ribose phosphate metabolic process GO:0019693 291 0.084
regulation of cellular ketone metabolic process GO:0010565 66 0.082
mitochondrion organization GO:0007005 134 0.081
purine ribonucleoside metabolic process GO:0046128 241 0.076
glycosyl compound metabolic process GO:1901657 246 0.076
ribonucleoside metabolic process GO:0009119 245 0.074
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.073
cellular ketone metabolic process GO:0042180 84 0.072
regulation of cellular amine metabolic process GO:0033238 20 0.071
response to organonitrogen compound GO:0010243 246 0.069
heterocycle catabolic process GO:0046700 280 0.068
cation transport GO:0006812 399 0.067
ion transmembrane transport GO:0034220 361 0.067
nucleoside metabolic process GO:0009116 246 0.065
regulation of cellular amino acid metabolic process GO:0006521 5 0.061
purine nucleotide catabolic process GO:0006195 211 0.060
inorganic cation transmembrane transport GO:0098662 207 0.058
nucleoside triphosphate metabolic process GO:0009141 230 0.057
oxidation reduction process GO:0055114 342 0.056
purine nucleoside triphosphate metabolic process GO:0009144 226 0.055
positive regulation of cellular amine metabolic process GO:0033240 5 0.055
renal system development GO:0072001 225 0.055
cellular lipid metabolic process GO:0044255 323 0.054
monocarboxylic acid metabolic process GO:0032787 191 0.053
Rat
inorganic ion transmembrane transport GO:0098660 234 0.053
macromolecule catabolic process GO:0009057 281 0.051
membrane organization GO:0061024 245 0.051
ribonucleoside triphosphate metabolic process GO:0009199 220 0.050
regulation of membrane potential GO:0042391 192 0.049
organic cyclic compound catabolic process GO:1901361 295 0.048
muscle system process GO:0003012 141 0.048
organophosphate catabolic process GO:0046434 232 0.048
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.047
purine ribonucleotide catabolic process GO:0009154 208 0.046
regulation of hydrolase activity GO:0051336 246 0.046
purine nucleoside catabolic process GO:0006152 205 0.046
ribonucleoside catabolic process GO:0042454 206 0.045
actin cytoskeleton organization GO:0030036 220 0.044
regulation of transferase activity GO:0051338 263 0.043
regulation of purine nucleotide metabolic process GO:1900542 169 0.043
cellular modified amino acid metabolic process GO:0006575 63 0.043
aromatic compound catabolic process GO:0019439 286 0.042
organonitrogen compound catabolic process GO:1901565 264 0.042
nucleoside monophosphate metabolic process GO:0009123 85 0.042
positive regulation of protein modification process GO:0031401 299 0.041
positive regulation of protein phosphorylation GO:0001934 242 0.041
regulation of cellular response to stress GO:0080135 159 0.040
purine nucleoside triphosphate catabolic process GO:0009146 203 0.039
nucleotide catabolic process GO:0009166 217 0.039
positive regulation of cell death GO:0010942 224 0.039
ribonucleotide catabolic process GO:0009261 208 0.038
ribonucleoside triphosphate catabolic process GO:0009203 199 0.038
nucleoside phosphate catabolic process GO:1901292 222 0.037
lipid biosynthetic process GO:0008610 179 0.037
purine ribonucleoside catabolic process GO:0046130 205 0.037
regulation of ion transport GO:0043269 215 0.036
regulation of neuron differentiation GO:0045664 281 0.036
epithelial tube morphogenesis GO:0060562 303 0.036
regulation of nucleotide metabolic process GO:0006140 169 0.035
spermatogenesis GO:0007283 284 0.035
fatty acid metabolic process GO:0006631 121 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.034
regulation of kinase activity GO:0043549 249 0.034
cation homeostasis GO:0055080 212 0.034
dephosphorylation GO:0016311 129 0.034
organic acid biosynthetic process GO:0016053 86 0.033
regulation of apoptotic signaling pathway GO:2001233 197 0.033
synaptic transmission GO:0007268 329 0.033
negative regulation of cell proliferation GO:0008285 296 0.033
protein catabolic process GO:0030163 221 0.033
ras protein signal transduction GO:0007265 77 0.033
positive regulation of apoptotic process GO:0043065 217 0.033
cellular nitrogen compound catabolic process GO:0044270 280 0.032
nucleoside triphosphate catabolic process GO:0009143 205 0.032
protein maturation GO:0051604 176 0.032
peptidyl amino acid modification GO:0018193 336 0.032
positive regulation of programmed cell death GO:0043068 218 0.031
atp metabolic process GO:0046034 75 0.031
endomembrane system organization GO:0010256 147 0.031
potassium ion homeostasis GO:0055075 4 0.031
purine containing compound catabolic process GO:0072523 213 0.030
carbohydrate metabolic process GO:0005975 230 0.030
action potential GO:0001508 78 0.030
regulation of secretion GO:0051046 274 0.030
maintenance of location GO:0051235 89 0.030
regulation of transmembrane transport GO:0034762 128 0.030
circulatory system process GO:0003013 197 0.029
male gamete generation GO:0048232 285 0.029
g protein coupled receptor signaling pathway GO:0007186 243 0.029
carboxylic acid biosynthetic process GO:0046394 86 0.029
ribonucleoside monophosphate metabolic process GO:0009161 80 0.028
response to oxidative stress GO:0006979 123 0.028
small molecule biosynthetic process GO:0044283 132 0.028
cytokine production GO:0001816 319 0.028
regulation of cellular catabolic process GO:0031329 242 0.028
adult behavior GO:0030534 135 0.028
striated muscle contraction GO:0006941 45 0.028
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.028
negative regulation of molecular function GO:0044092 258 0.027
small gtpase mediated signal transduction GO:0007264 97 0.027
apoptotic signaling pathway GO:0097190 306 0.027
urogenital system development GO:0001655 261 0.027
mapk cascade GO:0000165 281 0.027
sodium ion export from cell GO:0036376 1 0.026
regulation of organelle organization GO:0033043 289 0.026
positive regulation of cell development GO:0010720 237 0.026
regulation of cell projection organization GO:0031344 206 0.026
organonitrogen compound biosynthetic process GO:1901566 192 0.026
regulation of protein kinase activity GO:0045859 232 0.025
muscle cell differentiation GO:0042692 261 0.025
Fly
cellular response to hormone stimulus GO:0032870 150 0.025
positive regulation of nervous system development GO:0051962 221 0.025
kidney development GO:0001822 213 0.025
organelle fission GO:0048285 170 0.025
sensory perception GO:0007600 245 0.025
glycosyl compound catabolic process GO:1901658 206 0.025
microtubule based process GO:0007017 236 0.024
anatomical structure homeostasis GO:0060249 145 0.024
response to organic cyclic compound GO:0014070 198 0.024
negative regulation of phosphate metabolic process GO:0045936 184 0.023
response to growth factor GO:0070848 198 0.023
regulation of protein localization GO:0032880 231 0.023
learning or memory GO:0007611 148 0.023
substantia nigra development GO:0021762 2 0.023
germ cell development GO:0007281 185 0.023
nitrogen compound transport GO:0071705 271 0.023
muscle contraction GO:0006936 101 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.022
organophosphate biosynthetic process GO:0090407 122 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
cellular homeostasis GO:0019725 240 0.022
response to light stimulus GO:0009416 135 0.022
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.022
striated muscle tissue development GO:0014706 293 0.022
positive regulation of nucleotide metabolic process GO:0045981 114 0.022
multicellular organismal homeostasis GO:0048871 164 0.021
regulation of cell cycle GO:0051726 281 0.021
cellular chemical homeostasis GO:0055082 215 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
embryonic organ morphogenesis GO:0048562 276 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
dna metabolic process GO:0006259 303 0.021
organic hydroxy compound metabolic process GO:1901615 203 0.021
Rat
regulation of mapk cascade GO:0043408 248 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
cellular protein complex assembly GO:0043623 116 0.021
organelle localization GO:0051640 179 0.021
cellular response to lipid GO:0071396 145 0.021
transmission of nerve impulse GO:0019226 76 0.020
response to inorganic substance GO:0010035 96 0.020
regulation of anatomical structure size GO:0090066 178 0.020
rho protein signal transduction GO:0007266 32 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
glutathione metabolic process GO:0006749 16 0.020
neuromuscular process GO:0050905 99 0.020
energy derivation by oxidation of organic compounds GO:0015980 77 0.020
cell type specific apoptotic process GO:0097285 268 0.020
camera type eye development GO:0043010 266 0.020
generation of precursor metabolites and energy GO:0006091 103 0.019
locomotory behavior GO:0007626 195 0.019
intracellular protein transport GO:0006886 204 0.019
cell growth GO:0016049 130 0.019
microtubule based movement GO:0007018 84 0.019
response to extracellular stimulus GO:0009991 127 0.019
positive regulation of transferase activity GO:0051347 167 0.019
positive regulation of mapk cascade GO:0043410 170 0.019
nucleoside catabolic process GO:0009164 206 0.019
nucleoside monophosphate catabolic process GO:0009125 59 0.019
tissue homeostasis GO:0001894 115 0.019
fat cell differentiation GO:0045444 160 0.018
ribonucleoside monophosphate catabolic process GO:0009158 57 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
cellular carbohydrate metabolic process GO:0044262 119 0.018
positive regulation of cellular catabolic process GO:0031331 148 0.018
protein localization to membrane GO:0072657 108 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
cellular amide metabolic process GO:0043603 58 0.018
microtubule cytoskeleton organization GO:0000226 157 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
regulation of secretion by cell GO:1903530 249 0.018
response to radiation GO:0009314 165 0.018
cell adhesion GO:0007155 329 0.018
peptide metabolic process GO:0006518 46 0.018
purine nucleoside monophosphate metabolic process GO:0009126 81 0.017
regulation of cell motility GO:2000145 236 0.017
cellular ion homeostasis GO:0006873 165 0.017
cellular response to oxidative stress GO:0034599 76 0.017
fertilization GO:0009566 127 0.017
regulation of ion transmembrane transport GO:0034765 119 0.017
cellular response to inorganic substance GO:0071241 37 0.017
muscle tissue development GO:0060537 308 0.017
regulation of proteolysis GO:0030162 164 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
carboxylic acid transport GO:0046942 100 0.017
regulation of binding GO:0051098 111 0.017
negative regulation of transferase activity GO:0051348 85 0.017
positive regulation of ion transport GO:0043270 65 0.017
regionalization GO:0003002 337 0.016
response to oxygen levels GO:0070482 62 0.016
sensory organ morphogenesis GO:0090596 242 0.016
regulation of metal ion transport GO:0010959 106 0.016
positive regulation of neuron differentiation GO:0045666 141 0.016
leukocyte differentiation GO:0002521 342 0.016
actin filament organization GO:0007015 113 0.016
regulation of hormone levels GO:0010817 211 0.016
cellular respiration GO:0045333 38 0.016
regulation of purine nucleotide catabolic process GO:0033121 122 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
plasma membrane organization GO:0007009 90 0.016
neuronal action potential GO:0019228 54 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
response to peptide hormone GO:0043434 127 0.016
sulfur compound metabolic process GO:0006790 100 0.016
sodium ion transport GO:0006814 73 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
neurotransmitter transport GO:0006836 76 0.016
anion transport GO:0006820 177 0.016
organic anion transport GO:0015711 137 0.016
regulation of intracellular transport GO:0032386 159 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
positive regulation of growth GO:0045927 104 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
axonogenesis GO:0007409 274 0.015
epithelial cell development GO:0002064 159 0.015
cellular response to dna damage stimulus GO:0006974 207 0.015
cognition GO:0050890 149 0.015
blood circulation GO:0008015 195 0.015
atp catabolic process GO:0006200 55 0.015
regulation of cell migration GO:0030334 219 0.015
regulation of cell growth GO:0001558 91 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
response to acid chemical GO:0001101 111 0.015
cardiac muscle contraction GO:0060048 32 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
small molecule catabolic process GO:0044282 71 0.015
organelle assembly GO:0070925 177 0.015
regulation of cytokine production GO:0001817 266 0.015
mitotic cell cycle GO:0000278 195 0.015
developmental growth involved in morphogenesis GO:0060560 138 0.015
response to peptide GO:1901652 136 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
protein processing GO:0016485 163 0.014
chemotaxis GO:0006935 247 0.014
response to temperature stimulus GO:0009266 55 0.014
nuclear division GO:0000280 158 0.014
response to lipopolysaccharide GO:0032496 128 0.014
endocytosis GO:0006897 168 0.014
regulation of neuron projection development GO:0010975 169 0.014
regulation of transporter activity GO:0032409 57 0.014
cellular response to acid chemical GO:0071229 68 0.014
hydrogen transport GO:0006818 35 0.014
regulation of cellular component size GO:0032535 121 0.014
immune effector process GO:0002252 321 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
protein localization to organelle GO:0033365 185 0.014
phospholipid metabolic process GO:0006644 87 0.014
regulation of ras protein signal transduction GO:0046578 114 0.013
glial cell differentiation GO:0010001 131 0.013
respiratory system development GO:0060541 190 0.013
monocarboxylic acid biosynthetic process GO:0072330 61 0.013
inflammatory response GO:0006954 244 0.013
establishment of organelle localization GO:0051656 122 0.013
i kappab kinase nf kappab signaling GO:0007249 85 0.013
neuron death GO:0070997 154 0.013
steroid metabolic process GO:0008202 119 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
alcohol metabolic process GO:0006066 116 0.013
neuron neuron synaptic transmission GO:0007270 69 0.013
gtp catabolic process GO:0006184 143 0.013
negative regulation of nervous system development GO:0051961 156 0.013
ear development GO:0043583 200 0.013
regulation of protein transport GO:0051223 163 0.013
response to reactive oxygen species GO:0000302 56 0.013
multicellular organismal signaling GO:0035637 91 0.013
regulation of neuron death GO:1901214 134 0.013
divalent metal ion transport GO:0070838 172 0.013
heart morphogenesis GO:0003007 178 0.013
proton transport GO:0015992 35 0.013
neuron apoptotic process GO:0051402 142 0.013
lipid localization GO:0010876 126 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
nucleotide biosynthetic process GO:0009165 78 0.013
response to steroid hormone GO:0048545 56 0.013
calcium ion transport GO:0006816 159 0.013
chromatin organization GO:0006325 206 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
gtp metabolic process GO:0046039 144 0.013
innate immune response GO:0045087 157 0.013
regulation of system process GO:0044057 200 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
lipid modification GO:0030258 65 0.013
purine nucleoside monophosphate catabolic process GO:0009128 58 0.013
positive regulation of cell projection organization GO:0031346 95 0.013
protein ubiquitination GO:0016567 171 0.012
wnt signaling pathway GO:0016055 188 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
pole plasm assembly GO:0007315 2 0.012
coenzyme metabolic process GO:0006732 52 0.012
Rat
nucleocytoplasmic transport GO:0006913 139 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
retina development in camera type eye GO:0060041 119 0.012
negative regulation of cell development GO:0010721 169 0.012
hormone metabolic process GO:0042445 86 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
positive regulation of apoptotic signaling pathway GO:2001235 95 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
cofactor metabolic process GO:0051186 80 0.012
Rat
spermatid development GO:0007286 108 0.012
chromatin modification GO:0016568 187 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
gonad development GO:0008406 141 0.012
regulation of blood pressure GO:0008217 93 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
homeostasis of number of cells GO:0048872 210 0.012
negative regulation of hydrolase activity GO:0051346 71 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
negative regulation of protein modification process GO:0031400 163 0.012
positive regulation of sodium ion transmembrane transport GO:1902307 4 0.012
regulation of defense response GO:0031347 233 0.012
potassium ion transport GO:0006813 52 0.012
hexose metabolic process GO:0019318 98 0.012
cellular response to cadmium ion GO:0071276 3 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
regulation of phospholipid biosynthetic process GO:0071071 3 0.012
cytoskeleton dependent intracellular transport GO:0030705 50 0.012
regulation of sodium ion transmembrane transporter activity GO:2000649 9 0.012
alpha amino acid metabolic process GO:1901605 59 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
organic acid transport GO:0015849 101 0.012
potassium ion transmembrane transport GO:0071805 43 0.012
response to insulin GO:0032868 100 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
fatty acid biosynthetic process GO:0006633 41 0.011
metal ion homeostasis GO:0055065 189 0.011
blood vessel morphogenesis GO:0048514 285 0.011
myelination GO:0042552 74 0.011
regulation of mitochondrial fission GO:0090140 3 0.011
cytoplasmic transport GO:0016482 234 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
male sex differentiation GO:0046661 109 0.011
positive regulation of neuron projection development GO:0010976 79 0.011
negative regulation of kinase activity GO:0033673 81 0.011
regulation of angiogenesis GO:0045765 81 0.011
leukocyte migration GO:0050900 124 0.011
positive regulation of kinase activity GO:0033674 155 0.011
tube formation GO:0035148 140 0.011
purine containing compound biosynthetic process GO:0072522 70 0.011
rhythmic process GO:0048511 174 0.011
inner ear morphogenesis GO:0042472 101 0.011
circadian rhythm GO:0007623 114 0.011
myeloid cell differentiation GO:0030099 233 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
heart contraction GO:0060047 93 0.011
cell substrate adhesion GO:0031589 130 0.011
divalent inorganic cation transport GO:0072511 178 0.011
mitotic cell cycle process GO:1903047 159 0.011
cellular potassium ion transport GO:0071804 43 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.011
regulation of synaptic plasticity GO:0048167 87 0.011
erk1 and erk2 cascade GO:0070371 77 0.011
skeletal muscle organ development GO:0060538 163 0.011
glycerolipid metabolic process GO:0046486 122 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
negative regulation of neuron apoptotic process GO:0043524 92 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.011
regulation of multi organism process GO:0043900 111 0.011
apoptotic mitochondrial changes GO:0008637 48 0.011
monovalent inorganic cation homeostasis GO:0055067 33 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
lymphocyte differentiation GO:0030098 242 0.010
carbohydrate catabolic process GO:0016052 32 0.010
response to hypoxia GO:0001666 58 0.010
cell maturation GO:0048469 127 0.010
cellular response to biotic stimulus GO:0071216 92 0.010
jnk cascade GO:0007254 72 0.010
translation GO:0006412 93 0.010
regulation of cell activation GO:0050865 289 0.010
cellular response to peptide hormone stimulus GO:0071375 92 0.010
forebrain development GO:0030900 302 0.010
regulation of gtp catabolic process GO:0033124 113 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
regulation of t cell activation GO:0050863 170 0.010
organic hydroxy compound transport GO:0015850 93 0.010
carbohydrate homeostasis GO:0033500 128 0.010
glycerophospholipid metabolic process GO:0006650 71 0.010
monosaccharide metabolic process GO:0005996 106 0.010
gland development GO:0048732 330 0.010
multi multicellular organism process GO:0044706 109 0.010
telencephalon development GO:0021537 186 0.010
skin development GO:0043588 220 0.010

Ldhb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
nervous system disease DOID:863 0 0.052
central nervous system disease DOID:331 0 0.018
neurodegenerative disease DOID:1289 0 0.017
disease of metabolism DOID:0014667 0 0.013
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011