Mus musculus

27 known processes

Lrrc8a

leucine rich repeat containing 8A

(Aliases: MGC61242,mKIAA1437,Lrrc8)

Lrrc8a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.162
purine ribonucleotide metabolic process GO:0009150 290 0.145
response to organonitrogen compound GO:0010243 246 0.119
regulation of hydrolase activity GO:0051336 246 0.117
carbohydrate derivative catabolic process GO:1901136 231 0.112
homeostasis of number of cells GO:0048872 210 0.111
organonitrogen compound catabolic process GO:1901565 264 0.110
nucleoside triphosphate catabolic process GO:0009143 205 0.105
ribose phosphate metabolic process GO:0019693 291 0.103
ribonucleoside triphosphate catabolic process GO:0009203 199 0.102
ribonucleotide metabolic process GO:0009259 291 0.091
endocytosis GO:0006897 168 0.091
regulation of cellular ketone metabolic process GO:0010565 66 0.088
nucleoside triphosphate metabolic process GO:0009141 230 0.086
negative regulation of cell proliferation GO:0008285 296 0.083
purine nucleoside metabolic process GO:0042278 241 0.083
purine nucleotide metabolic process GO:0006163 302 0.082
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.081
ribonucleoside triphosphate metabolic process GO:0009199 220 0.081
amine metabolic process GO:0009308 45 0.079
nucleoside phosphate metabolic process GO:0006753 338 0.079
regulation of organelle organization GO:0033043 289 0.077
ribonucleoside metabolic process GO:0009119 245 0.076
glycosyl compound catabolic process GO:1901658 206 0.075
ribonucleotide catabolic process GO:0009261 208 0.075
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.074
regulation of cellular amino acid metabolic process GO:0006521 5 0.072
nucleotide metabolic process GO:0009117 332 0.071
embryonic organ morphogenesis GO:0048562 276 0.070
purine nucleoside triphosphate metabolic process GO:0009144 226 0.070
purine ribonucleoside metabolic process GO:0046128 241 0.069
negative regulation of protein metabolic process GO:0051248 282 0.069
cellular amino acid metabolic process GO:0006520 103 0.068
purine nucleoside catabolic process GO:0006152 205 0.068
purine ribonucleotide catabolic process GO:0009154 208 0.066
myeloid cell differentiation GO:0030099 233 0.066
positive regulation of cell death GO:0010942 224 0.066
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.065
cell adhesion GO:0007155 329 0.064
cation transport GO:0006812 399 0.064
regulation of cellular amine metabolic process GO:0033238 20 0.064
erythrocyte differentiation GO:0030218 88 0.063
nucleoside catabolic process GO:0009164 206 0.063
positive regulation of cellular amine metabolic process GO:0033240 5 0.063
cellular amine metabolic process GO:0044106 44 0.061
cellular nitrogen compound catabolic process GO:0044270 280 0.061
nucleoside metabolic process GO:0009116 246 0.061
carbohydrate metabolic process GO:0005975 230 0.060
membrane organization GO:0061024 245 0.060
reactive oxygen species metabolic process GO:0072593 84 0.059
wound healing GO:0042060 157 0.059
cell junction assembly GO:0034329 52 0.056
purine containing compound metabolic process GO:0072521 311 0.055
nucleoside phosphate catabolic process GO:1901292 222 0.054
exocytosis GO:0006887 121 0.053
glycosyl compound metabolic process GO:1901657 246 0.053
cell cell junction organization GO:0045216 72 0.052
small gtpase mediated signal transduction GO:0007264 97 0.052
ion transmembrane transport GO:0034220 361 0.052
Human
intracellular protein transport GO:0006886 204 0.051
nucleobase containing small molecule metabolic process GO:0055086 352 0.051
inflammatory response GO:0006954 244 0.051
cellular homeostasis GO:0019725 240 0.051
Human
muscle cell differentiation GO:0042692 261 0.051
regulation of cell motility GO:2000145 236 0.050
regulation of sphingolipid mediated signaling pathway GO:1902068 2 0.050
guanosine containing compound metabolic process GO:1901068 144 0.050
nucleotide catabolic process GO:0009166 217 0.050
striated muscle tissue development GO:0014706 293 0.050
purine nucleoside triphosphate catabolic process GO:0009146 203 0.049
fat cell differentiation GO:0045444 160 0.049
Mouse
negative regulation of molecular function GO:0044092 258 0.048
myotube differentiation GO:0014902 105 0.047
heterocycle catabolic process GO:0046700 280 0.047
positive regulation of apoptotic process GO:0043065 217 0.047
protein localization to membrane GO:0072657 108 0.046
cellular carbohydrate metabolic process GO:0044262 119 0.046
positive regulation of programmed cell death GO:0043068 218 0.046
gtp metabolic process GO:0046039 144 0.046
purine ribonucleoside catabolic process GO:0046130 205 0.046
cellular response to growth factor stimulus GO:0071363 197 0.046
cell matrix adhesion GO:0007160 68 0.045
positive regulation of protein modification process GO:0031401 299 0.045
guanosine containing compound catabolic process GO:1901069 144 0.044
purine containing compound catabolic process GO:0072523 213 0.044
positive regulation of cell migration GO:0030335 109 0.043
camera type eye development GO:0043010 266 0.042
carbohydrate derivative biosynthetic process GO:1901137 183 0.042
regulation of cellular catabolic process GO:0031329 242 0.042
wnt signaling pathway GO:0016055 188 0.042
apoptotic signaling pathway GO:0097190 306 0.041
lipid biosynthetic process GO:0008610 179 0.040
ribonucleoside catabolic process GO:0042454 206 0.040
regulation of transferase activity GO:0051338 263 0.040
cation transmembrane transport GO:0098655 266 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
negative regulation of cellular amine metabolic process GO:0033239 1 0.037
cellular response to hormone stimulus GO:0032870 150 0.037
regulation of vesicle mediated transport GO:0060627 139 0.037
positive regulation of protein phosphorylation GO:0001934 242 0.036
organonitrogen compound biosynthetic process GO:1901566 192 0.036
organic cyclic compound catabolic process GO:1901361 295 0.036
organelle localization GO:0051640 179 0.035
cell junction organization GO:0034330 77 0.035
ossification GO:0001503 216 0.035
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.035
peptidyl amino acid modification GO:0018193 336 0.035
t cell activation GO:0042110 289 0.035
purine nucleotide catabolic process GO:0006195 211 0.035
regulation of cell cycle GO:0051726 281 0.034
cellular response to organonitrogen compound GO:0071417 145 0.034
organophosphate catabolic process GO:0046434 232 0.034
g protein coupled receptor signaling pathway GO:0007186 243 0.034
axonogenesis GO:0007409 274 0.034
regulation of purine nucleotide metabolic process GO:1900542 169 0.034
gtp catabolic process GO:0006184 143 0.034
blood circulation GO:0008015 195 0.033
aromatic compound catabolic process GO:0019439 286 0.033
regulation of mapk cascade GO:0043408 248 0.033
cellular response to peptide GO:1901653 92 0.033
male gamete generation GO:0048232 285 0.033
lateral inhibition GO:0046331 1 0.033
actin filament organization GO:0007015 113 0.032
regulation of cellular response to stress GO:0080135 159 0.032
regulation of protein localization GO:0032880 231 0.032
cytoplasmic transport GO:0016482 234 0.032
negative regulation of cellular component organization GO:0051129 194 0.032
single organism cell adhesion GO:0098602 156 0.031
stem cell development GO:0048864 219 0.031
canonical wnt signaling pathway GO:0060070 130 0.031
regulation of reactive oxygen species metabolic process GO:2000377 40 0.031
stem cell differentiation GO:0048863 268 0.031
regulation of wnt signaling pathway GO:0030111 123 0.030
angiogenesis GO:0001525 201 0.030
morphogenesis of a branching epithelium GO:0061138 193 0.030
muscle tissue development GO:0060537 308 0.030
regulation of cell activation GO:0050865 289 0.029
gland development GO:0048732 330 0.029
response to organic cyclic compound GO:0014070 198 0.029
response to growth factor GO:0070848 198 0.029
negative regulation of phosphate metabolic process GO:0045936 184 0.029
response to oxygen levels GO:0070482 62 0.029
cell type specific apoptotic process GO:0097285 268 0.029
endomembrane system organization GO:0010256 147 0.029
ras protein signal transduction GO:0007265 77 0.029
digestive system development GO:0055123 200 0.028
kidney development GO:0001822 213 0.028
cellular lipid metabolic process GO:0044255 323 0.028
multicellular organismal homeostasis GO:0048871 164 0.028
oxidation reduction process GO:0055114 342 0.028
transmembrane transport GO:0055085 412 0.028
Human
regulation of apoptotic signaling pathway GO:2001233 197 0.028
microtubule cytoskeleton organization GO:0000226 157 0.028
regulation of intracellular transport GO:0032386 159 0.028
protein localization to organelle GO:0033365 185 0.027
regulation of inflammatory response GO:0050727 147 0.027
response to radiation GO:0009314 165 0.027
negative regulation of intracellular signal transduction GO:1902532 167 0.027
multi multicellular organism process GO:0044706 109 0.027
dna metabolic process GO:0006259 303 0.027
gastrulation GO:0007369 116 0.026
divalent inorganic cation transport GO:0072511 178 0.026
negative regulation of protein phosphorylation GO:0001933 126 0.026
skeletal muscle organ development GO:0060538 163 0.026
regulation of cell migration GO:0030334 219 0.026
protein modification by small protein conjugation GO:0032446 187 0.025
extrinsic apoptotic signaling pathway GO:0097191 126 0.025
mapk cascade GO:0000165 281 0.025
response to inorganic substance GO:0010035 96 0.025
negative regulation of immune system process GO:0002683 209 0.025
transmission of nerve impulse GO:0019226 76 0.025
i kappab kinase nf kappab signaling GO:0007249 85 0.025
response to oxidative stress GO:0006979 123 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
blood vessel morphogenesis GO:0048514 285 0.025
nuclear transport GO:0051169 139 0.025
cellular response to peptide hormone stimulus GO:0071375 92 0.025
regulation of cellular component biogenesis GO:0044087 181 0.024
macromolecule catabolic process GO:0009057 281 0.024
epidermis development GO:0008544 187 0.024
epithelial cell development GO:0002064 159 0.024
regulation of ossification GO:0030278 112 0.024
inorganic cation transmembrane transport GO:0098662 207 0.024
positive regulation of cell development GO:0010720 237 0.024
regulation of interleukin 8 production GO:0032677 3 0.024
regulation of homeostatic process GO:0032844 182 0.024
circulatory system process GO:0003013 197 0.023
inorganic ion transmembrane transport GO:0098660 234 0.023
cell substrate adhesion GO:0031589 130 0.023
epithelial tube morphogenesis GO:0060562 303 0.023
regulation of fat cell differentiation GO:0045598 81 0.023
myeloid cell homeostasis GO:0002262 114 0.023
negative regulation of wnt signaling pathway GO:0030178 73 0.023
regulation of ion transport GO:0043269 215 0.023
positive regulation of mapk cascade GO:0043410 170 0.022
glycoprotein metabolic process GO:0009100 116 0.022
negative regulation of protein modification process GO:0031400 163 0.022
protein catabolic process GO:0030163 221 0.022
compound eye development GO:0048749 1 0.022
adherens junction assembly GO:0034333 22 0.022
anatomical structure homeostasis GO:0060249 145 0.022
interleukin 8 production GO:0032637 4 0.022
regulation of nucleoside metabolic process GO:0009118 130 0.022
dephosphorylation GO:0016311 129 0.022
regulation of nucleotide metabolic process GO:0006140 169 0.022
multicellular organismal signaling GO:0035637 91 0.022
developmental growth involved in morphogenesis GO:0060560 138 0.021
maintenance of location GO:0051235 89 0.021
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
striated muscle cell development GO:0055002 125 0.021
cellular chemical homeostasis GO:0055082 215 0.021
negative regulation of cell cycle GO:0045786 123 0.021
regulation of cell cycle process GO:0010564 160 0.021
ribose phosphate biosynthetic process GO:0046390 59 0.021
mitotic cell cycle process GO:1903047 159 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.021
response to light stimulus GO:0009416 135 0.021
regulation of anatomical structure size GO:0090066 178 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.021
intrinsic apoptotic signaling pathway GO:0097193 132 0.020
synaptic transmission GO:0007268 329 0.020
response to peptide hormone GO:0043434 127 0.020
positive regulation of gtp catabolic process GO:0033126 85 0.020
glycoprotein biosynthetic process GO:0009101 89 0.020
negative regulation of apoptotic signaling pathway GO:2001234 104 0.020
positive regulation of transferase activity GO:0051347 167 0.020
syncytium formation GO:0006949 43 0.020
organ growth GO:0035265 117 0.020
glucose homeostasis GO:0042593 128 0.020
regulation of cell growth GO:0001558 91 0.020
mitotic cell cycle GO:0000278 195 0.020
endothelial cell differentiation GO:0045446 41 0.020
regulation of neuron projection development GO:0010975 169 0.020
t cell differentiation GO:0030217 174 0.020
protein targeting GO:0006605 143 0.020
negative regulation of hydrolase activity GO:0051346 71 0.020
morphogenesis of a branching structure GO:0001763 203 0.020
regulation of lymphocyte activation GO:0051249 240 0.019
generation of precursor metabolites and energy GO:0006091 103 0.019
tube formation GO:0035148 140 0.019
establishment of protein localization to membrane GO:0090150 54 0.019
regulation of osteoblast differentiation GO:0045667 67 0.019
sphingolipid metabolic process GO:0006665 45 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
telencephalon development GO:0021537 186 0.019
multicellular organism growth GO:0035264 161 0.019
regulation of leukocyte differentiation GO:1902105 159 0.019
signal transduction by p53 class mediator GO:0072331 51 0.018
anion transport GO:0006820 177 0.018
Human
organophosphate biosynthetic process GO:0090407 122 0.018
regionalization GO:0003002 337 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
protein localization to plasma membrane GO:0072659 57 0.018
cytokine mediated signaling pathway GO:0019221 115 0.018
gonad development GO:0008406 141 0.018
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.018
focal adhesion assembly GO:0048041 19 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.018
hexose metabolic process GO:0019318 98 0.018
muscle cell development GO:0055001 133 0.018
positive regulation of gtpase activity GO:0043547 85 0.018
spermatogenesis GO:0007283 284 0.018
monosaccharide metabolic process GO:0005996 106 0.018
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.018
rho protein signal transduction GO:0007266 32 0.018
regulation of membrane potential GO:0042391 192 0.018
positive regulation of nervous system development GO:0051962 221 0.018
glycosylation GO:0070085 62 0.018
response to reactive oxygen species GO:0000302 56 0.018
response to transforming growth factor beta GO:0071559 88 0.017
cell growth GO:0016049 130 0.017
establishment of organelle localization GO:0051656 122 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
regulation of lipid metabolic process GO:0019216 118 0.017
cellular response to cytokine stimulus GO:0071345 189 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
response to hypoxia GO:0001666 58 0.017
regulation of protein kinase activity GO:0045859 232 0.017
positive regulation of homeostatic process GO:0032846 64 0.017
skin development GO:0043588 220 0.017
response to peptide GO:1901652 136 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
negative regulation of defense response GO:0031348 77 0.017
regulation of canonical wnt signaling pathway GO:0060828 82 0.017
urogenital system development GO:0001655 261 0.017
organelle fission GO:0048285 170 0.017
leukocyte migration GO:0050900 124 0.017
regulation of protein maturation GO:1903317 96 0.017
tissue homeostasis GO:0001894 115 0.017
regulation of neuron differentiation GO:0045664 281 0.017
response to decreased oxygen levels GO:0036293 59 0.017
plasma membrane organization GO:0007009 90 0.017
regulation of feeding behavior GO:0060259 3 0.017
action potential GO:0001508 78 0.017
response to lipopolysaccharide GO:0032496 128 0.017
regulation of lipid biosynthetic process GO:0046890 54 0.016
positive regulation of organelle organization GO:0010638 128 0.016
carbohydrate homeostasis GO:0033500 128 0.016
regulation of cell adhesion GO:0030155 154 0.016
protein ubiquitination GO:0016567 171 0.016
stress activated mapk cascade GO:0051403 80 0.016
regulation of protein processing GO:0070613 96 0.016
placenta development GO:0001890 140 0.016
regulation of purine nucleotide catabolic process GO:0033121 122 0.016
neuron migration GO:0001764 122 0.016
transition metal ion transport GO:0000041 38 0.016
positive regulation of cellular component biogenesis GO:0044089 94 0.016
regulation of hippo signaling GO:0035330 1 0.016
fertilization GO:0009566 127 0.016
hindbrain development GO:0030902 128 0.016
regulation of neuron death GO:1901214 134 0.016
respiratory system development GO:0060541 190 0.016
ear development GO:0043583 200 0.016
cellular protein complex assembly GO:0043623 116 0.016
extracellular matrix organization GO:0030198 147 0.016
protein oligomerization GO:0051259 67 0.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.015
macromolecule glycosylation GO:0043413 55 0.015
protein processing GO:0016485 163 0.015
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.015
sensory organ morphogenesis GO:0090596 242 0.015
epithelial cell proliferation GO:0050673 174 0.015
actomyosin structure organization GO:0031032 56 0.015
regulation of defense response GO:0031347 233 0.015
actin cytoskeleton organization GO:0030036 220 0.015
negative regulation of organelle organization GO:0010639 90 0.015
protein maturation GO:0051604 176 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
nuclear division GO:0000280 158 0.015
positive regulation of cell motility GO:2000147 116 0.015
nuclear import GO:0051170 95 0.015
positive regulation of kinase activity GO:0033674 155 0.015
ribonucleotide biosynthetic process GO:0009260 59 0.015
protein glycosylation GO:0006486 55 0.015
embryonic placenta development GO:0001892 98 0.015
positive regulation of secretion by cell GO:1903532 114 0.015
sequestering of metal ion GO:0051238 19 0.015
skeletal system morphogenesis GO:0048705 203 0.015
neuronal action potential GO:0019228 54 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
limb morphogenesis GO:0035108 149 0.015
regulation of metal ion transport GO:0010959 106 0.015
apical constriction GO:0003383 4 0.015
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.015
cell fate commitment GO:0045165 210 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
negative regulation of cell development GO:0010721 169 0.015
sulfur compound metabolic process GO:0006790 100 0.015
single organismal cell cell adhesion GO:0016337 131 0.014
bmp signaling pathway GO:0030509 93 0.014
cell maturation GO:0048469 127 0.014
regulation of adaptive immune response GO:0002819 90 0.014
regulation of proteolysis GO:0030162 164 0.014
regulation of protein catabolic process GO:0042176 108 0.014
negative regulation of neuron apoptotic process GO:0043524 92 0.014
cerebral cortex development GO:0021987 86 0.014
signal transduction in absence of ligand GO:0038034 55 0.014
actin filament bundle assembly GO:0051017 40 0.014
endocardial cell differentiation GO:0060956 4 0.014
neuron death GO:0070997 154 0.014
regulation of myeloid cell differentiation GO:0045637 96 0.014
negative regulation of proteolysis GO:0045861 74 0.014
response to nutrient levels GO:0031667 109 0.014
immune effector process GO:0002252 321 0.014
mitotic cytokinesis GO:0000281 4 0.014
lipid localization GO:0010876 126 0.014
syncytium formation by plasma membrane fusion GO:0000768 42 0.014
sensory perception GO:0007600 245 0.014
myosin filament assembly GO:0031034 2 0.014
extracellular structure organization GO:0043062 148 0.014
renal system development GO:0072001 225 0.014
branching morphogenesis of an epithelial tube GO:0048754 159 0.014
negative regulation of protein maturation GO:1903318 79 0.014
p38mapk cascade GO:0038066 4 0.014
nucleoside monophosphate metabolic process GO:0009123 85 0.014
cellular ion homeostasis GO:0006873 165 0.014
sequestering of calcium ion GO:0051208 18 0.014
heart process GO:0003015 94 0.014
response to steroid hormone GO:0048545 56 0.014
cell division GO:0051301 120 0.014
dna repair GO:0006281 107 0.014
regulation of exocytosis GO:0017157 61 0.014
positive regulation of gene silencing by mirna GO:2000637 1 0.014
negative regulation of cell migration GO:0030336 59 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
cellular response to lipid GO:0071396 145 0.014
membrane tubulation GO:0097320 4 0.014
heart contraction GO:0060047 93 0.014
negative regulation of epidermal growth factor activated receptor activity GO:0007175 3 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
developmental cell growth GO:0048588 84 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.014
tube closure GO:0060606 91 0.014
purine nucleotide biosynthetic process GO:0006164 65 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
regulation of response to wounding GO:1903034 189 0.013
positive regulation of interleukin 8 production GO:0032757 2 0.013
regulation of secretion by cell GO:1903530 249 0.013
regulation of kinase activity GO:0043549 249 0.013
cellular response to insulin stimulus GO:0032869 78 0.013
cellular protein catabolic process GO:0044257 155 0.013
regulation of cellular response to growth factor stimulus GO:0090287 82 0.013
cellularization GO:0007349 1 0.013
nitrogen compound transport GO:0071705 271 0.013
locomotory behavior GO:0007626 195 0.013
learning GO:0007612 98 0.013
organic hydroxy compound transport GO:0015850 93 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
negative regulation of growth GO:0045926 99 0.013
regulation of secretion GO:0051046 274 0.013
negative regulation of ossification GO:0030279 49 0.013
digestive tract morphogenesis GO:0048546 147 0.013
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 2 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
stem cell maintenance GO:0019827 130 0.013
retrograde transport endosome to golgi GO:0042147 2 0.013
nucleoside monophosphate catabolic process GO:0009125 59 0.013
purine ribonucleotide biosynthetic process GO:0009152 59 0.013
response to insulin GO:0032868 100 0.013
negative regulation of fat cell differentiation GO:0045599 36 0.013
cell substrate adherens junction assembly GO:0007045 19 0.013
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.013
response to extracellular stimulus GO:0009991 127 0.013
atp metabolic process GO:0046034 75 0.013
glial cell differentiation GO:0010001 131 0.013
positive regulation of podosome assembly GO:0071803 3 0.013
glucose metabolic process GO:0006006 92 0.013
regulation of stem cell differentiation GO:2000736 50 0.013
regulation of stress activated mapk cascade GO:0032872 69 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
vesicle localization GO:0051648 86 0.012
positive regulation of secretion GO:0051047 130 0.012
skeletal muscle cell differentiation GO:0035914 66 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
limb development GO:0060173 166 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
forebrain development GO:0030900 302 0.012
activation of adenylate cyclase activity GO:0007190 4 0.012
positive regulation of apoptotic process involved in morphogenesis GO:1902339 4 0.012
neural tube development GO:0021915 160 0.012
regulation of cell projection organization GO:0031344 206 0.012
muscle system process GO:0003012 141 0.012
regulation of p38mapk cascade GO:1900744 3 0.012
retina development in camera type eye GO:0060041 119 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
microtubule based process GO:0007017 236 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
skeletal system development GO:0001501 356 0.012
cell recognition GO:0008037 83 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
glycerophospholipid metabolic process GO:0006650 71 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
regulation of cellular component size GO:0032535 121 0.012
protein localization to nucleus GO:0034504 121 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
cardiocyte differentiation GO:0035051 87 0.012
cardiac cell fate specification GO:0060912 2 0.012
negative regulation of transferase activity GO:0051348 85 0.012
ensheathment of neurons GO:0007272 76 0.012
negative regulation of cell size GO:0045792 3 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
regulation of cytokine production GO:0001817 266 0.012
ameboidal type cell migration GO:0001667 128 0.012
positive regulation of nucleotide catabolic process GO:0030813 88 0.012
mesoderm morphogenesis GO:0048332 64 0.012
membrane lipid biosynthetic process GO:0046467 32 0.012
cellular response to amino acid stimulus GO:0071230 29 0.012
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.011
cell cell junction assembly GO:0007043 27 0.011
cyclic nucleotide metabolic process GO:0009187 59 0.011
response to acid chemical GO:0001101 111 0.011
activation of mapkkk activity GO:0000185 1 0.011
regulation of binding GO:0051098 111 0.011
regulation of endocytosis GO:0030100 69 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.011
cellular response to abiotic stimulus GO:0071214 56 0.011

Lrrc8a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.045
inherited metabolic disorder DOID:655 0 0.024
disease of anatomical entity DOID:7 0 0.024
Human
nervous system disease DOID:863 0 0.024
immune system disease DOID:2914 0 0.019
Human
hematopoietic system disease DOID:74 0 0.019
Human
bone development disease DOID:0080006 0 0.018
bone disease DOID:0080001 0 0.018
musculoskeletal system disease DOID:17 0 0.018
connective tissue disease DOID:65 0 0.018
sensory system disease DOID:0050155 0 0.013
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
acquired metabolic disease DOID:0060158 0 0.012