Mus musculus

2 known processes

Pla2g4e

phospholipase A2, group IVE

(Aliases: 2310026J01Rik,Pla2epsilon,C230096D22)

Pla2g4e biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.151
ion transmembrane transport GO:0034220 361 0.096
muscle tissue development GO:0060537 308 0.079
striated muscle tissue development GO:0014706 293 0.076
striated muscle cell development GO:0055002 125 0.057
muscle cell differentiation GO:0042692 261 0.054
cation transport GO:0006812 399 0.053
cation transmembrane transport GO:0098655 266 0.050
nitrogen compound transport GO:0071705 271 0.049
regulation of ion transport GO:0043269 215 0.045
cellular amino acid metabolic process GO:0006520 103 0.043
negative regulation of cell proliferation GO:0008285 296 0.042
regulation of system process GO:0044057 200 0.036
muscle cell development GO:0055001 133 0.036
regulation of transmembrane transport GO:0034762 128 0.035
camera type eye development GO:0043010 266 0.034
inorganic ion transmembrane transport GO:0098660 234 0.033
apoptotic signaling pathway GO:0097190 306 0.033
regulation of membrane potential GO:0042391 192 0.033
regulation of cellular catabolic process GO:0031329 242 0.033
organelle localization GO:0051640 179 0.033
regulation of cell projection organization GO:0031344 206 0.032
cellular protein complex assembly GO:0043623 116 0.031
regulation of cellular component biogenesis GO:0044087 181 0.031
g protein coupled receptor signaling pathway GO:0007186 243 0.031
regulation of hydrolase activity GO:0051336 246 0.030
calcium ion transport GO:0006816 159 0.030
myotube differentiation GO:0014902 105 0.030
cellular ketone metabolic process GO:0042180 84 0.029
heterocycle catabolic process GO:0046700 280 0.028
cytoplasmic transport GO:0016482 234 0.028
carboxylic acid transport GO:0046942 100 0.028
Mouse
synaptic transmission GO:0007268 329 0.027
adult behavior GO:0030534 135 0.027
regulation of purine nucleotide catabolic process GO:0033121 122 0.027
cellular amine metabolic process GO:0044106 44 0.027
nucleotide metabolic process GO:0009117 332 0.027
ras protein signal transduction GO:0007265 77 0.026
cell adhesion GO:0007155 329 0.026
ribonucleoside triphosphate catabolic process GO:0009203 199 0.026
aromatic compound catabolic process GO:0019439 286 0.026
regulation of feeding behavior GO:0060259 3 0.025
skeletal muscle fiber development GO:0048741 58 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
regulation of protein localization GO:0032880 231 0.025
regulation of nucleotide metabolic process GO:0006140 169 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
glycosyl compound metabolic process GO:1901657 246 0.024
response to organonitrogen compound GO:0010243 246 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
cellular lipid metabolic process GO:0044255 323 0.024
Mouse
chemotaxis GO:0006935 247 0.024
regulation of ion transmembrane transport GO:0034765 119 0.024
regulation of body fluid levels GO:0050878 162 0.024
regulation of cellular amine metabolic process GO:0033238 20 0.024
purine nucleotide metabolic process GO:0006163 302 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
regulation of cellular ketone metabolic process GO:0010565 66 0.023
organic cyclic compound catabolic process GO:1901361 295 0.023
sequestering of calcium ion GO:0051208 18 0.022
angiogenesis GO:0001525 201 0.022
regulation of muscle tissue development GO:1901861 97 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
actin cytoskeleton organization GO:0030036 220 0.022
skin development GO:0043588 220 0.022
ribose phosphate metabolic process GO:0019693 291 0.022
sequestering of metal ion GO:0051238 19 0.022
positive regulation of protein modification process GO:0031401 299 0.022
regulation of organelle organization GO:0033043 289 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
positive regulation of cell development GO:0010720 237 0.021
blood vessel morphogenesis GO:0048514 285 0.021
actin filament organization GO:0007015 113 0.021
purine nucleotide catabolic process GO:0006195 211 0.021
skeletal muscle organ development GO:0060538 163 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
nucleoside catabolic process GO:0009164 206 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
regulation of mapk cascade GO:0043408 248 0.020
calcium ion transmembrane transport GO:0070588 85 0.020
amine metabolic process GO:0009308 45 0.020
muscle fiber development GO:0048747 76 0.020
single organism cell adhesion GO:0098602 156 0.020
regulation of neuron differentiation GO:0045664 281 0.020
multicellular organismal signaling GO:0035637 91 0.020
regulation of metal ion transport GO:0010959 106 0.020
epidermis development GO:0008544 187 0.020
divalent inorganic cation transport GO:0072511 178 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
adult locomotory behavior GO:0008344 91 0.019
protein ubiquitination GO:0016567 171 0.019
mapk cascade GO:0000165 281 0.019
regulation of neuron projection development GO:0010975 169 0.019
heart contraction GO:0060047 93 0.019
nucleotide catabolic process GO:0009166 217 0.019
response to organic cyclic compound GO:0014070 198 0.019
Mouse
purine nucleoside metabolic process GO:0042278 241 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
wound healing GO:0042060 157 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
purine containing compound catabolic process GO:0072523 213 0.019
intracellular protein transport GO:0006886 204 0.019
regulation of cell motility GO:2000145 236 0.019
organophosphate catabolic process GO:0046434 232 0.019
regulation of proteolysis GO:0030162 164 0.018
regulation of cell migration GO:0030334 219 0.018
cellular component assembly involved in morphogenesis GO:0010927 139 0.018
maintenance of location GO:0051235 89 0.018
regulation of voltage gated calcium channel activity GO:1901385 4 0.018
regulation of cell cycle GO:0051726 281 0.018
nucleoside metabolic process GO:0009116 246 0.018
membrane organization GO:0061024 245 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
oxidation reduction process GO:0055114 342 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
macromolecule catabolic process GO:0009057 281 0.018
cognition GO:0050890 149 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
defense response to other organism GO:0098542 197 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
actin mediated cell contraction GO:0070252 15 0.018
divalent metal ion transport GO:0070838 172 0.018
regulation of nucleoside metabolic process GO:0009118 130 0.018
response to acid chemical GO:0001101 111 0.018
learning or memory GO:0007611 148 0.018
regulation of cellular amino acid metabolic process GO:0006521 5 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
positive regulation of kinase activity GO:0033674 155 0.018
locomotory behavior GO:0007626 195 0.017
gland development GO:0048732 330 0.017
fertilization GO:0009566 127 0.017
nuclear transport GO:0051169 139 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
organic anion transport GO:0015711 137 0.017
Mouse
sensory perception of mechanical stimulus GO:0050954 107 0.017
purine containing compound metabolic process GO:0072521 311 0.017
leukocyte differentiation GO:0002521 342 0.017
gliogenesis GO:0042063 141 0.017
regulation of cell activation GO:0050865 289 0.017
negative regulation of organelle organization GO:0010639 90 0.017
sa node cell action potential GO:0086015 4 0.016
myosin filament assembly GO:0031034 2 0.016
protein processing GO:0016485 163 0.016
immune effector process GO:0002252 321 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
transmission of nerve impulse GO:0019226 76 0.016
rho protein signal transduction GO:0007266 32 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
positive regulation of mapk cascade GO:0043410 170 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
circulatory system process GO:0003013 197 0.016
positive regulation of nervous system development GO:0051962 221 0.016
male genitalia morphogenesis GO:0048808 4 0.016
regulation of cytokine production GO:0001817 266 0.016
regulation of secretion by cell GO:1903530 249 0.016
cation homeostasis GO:0055080 212 0.016
regulation of myotube differentiation GO:0010830 62 0.016
male anatomical structure morphogenesis GO:0090598 4 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
peptidyl amino acid modification GO:0018193 336 0.015
regulation of striated muscle cell differentiation GO:0051153 81 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
glycosyl compound catabolic process GO:1901658 206 0.015
axonogenesis GO:0007409 274 0.015
action potential GO:0001508 78 0.015
positive regulation of nucleotide metabolic process GO:0045981 114 0.015
establishment of organelle localization GO:0051656 122 0.015
cellular ion homeostasis GO:0006873 165 0.015
cellular carbohydrate metabolic process GO:0044262 119 0.015
sensory perception GO:0007600 245 0.015
innate immune response GO:0045087 157 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
cellular response to organic cyclic compound GO:0071407 87 0.015
Mouse
cardiac muscle tissue development GO:0048738 130 0.015
stem cell differentiation GO:0048863 268 0.015
extrinsic apoptotic signaling pathway GO:0097191 126 0.015
organelle assembly GO:0070925 177 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
germ cell development GO:0007281 185 0.015
defecation GO:0030421 1 0.015
compound eye development GO:0048749 1 0.015
striated muscle myosin thick filament assembly GO:0071688 1 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
Mouse
homeostasis of number of cells GO:0048872 210 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
protein maturation GO:0051604 176 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
epithelial tube morphogenesis GO:0060562 303 0.014
regulation of secretion GO:0051046 274 0.014
lymphocyte differentiation GO:0030098 242 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
cell type specific apoptotic process GO:0097285 268 0.014
cellular homeostasis GO:0019725 240 0.014
organic hydroxy compound transport GO:0015850 93 0.014
dna metabolic process GO:0006259 303 0.014
myeloid cell differentiation GO:0030099 233 0.014
positive regulation of gtp catabolic process GO:0033126 85 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
mitotic cell cycle GO:0000278 195 0.014
multicellular organism growth GO:0035264 161 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
heart process GO:0003015 94 0.014
negative regulation of cell development GO:0010721 169 0.014
conditioned taste aversion GO:0001661 4 0.014
metal ion homeostasis GO:0055065 189 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
positive regulation of cell projection organization GO:0031346 95 0.014
reactive oxygen species metabolic process GO:0072593 84 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
protein localization to organelle GO:0033365 185 0.013
single organismal cell cell adhesion GO:0016337 131 0.013
regulation of angiogenesis GO:0045765 81 0.013
regulation of hormone levels GO:0010817 211 0.013
protein catabolic process GO:0030163 221 0.013
fat cell differentiation GO:0045444 160 0.013
blood circulation GO:0008015 195 0.013
regulation of vasculature development GO:1901342 88 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
microtubule based process GO:0007017 236 0.013
actin filament based movement GO:0030048 23 0.013
protein polymerization GO:0051258 57 0.013
positive regulation of transferase activity GO:0051347 167 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
placenta development GO:0001890 140 0.013
regulation of ion homeostasis GO:2000021 64 0.013
response to growth factor GO:0070848 198 0.013
fatty acid metabolic process GO:0006631 121 0.012
Mouse
sensory perception of sound GO:0007605 97 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
carbohydrate metabolic process GO:0005975 230 0.012
t cell activation GO:0042110 289 0.012
cellular response to lipid GO:0071396 145 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
protein secretion GO:0009306 111 0.012
nuclear division GO:0000280 158 0.012
renal system development GO:0072001 225 0.012
blastocyst development GO:0001824 80 0.012
myotube cell development GO:0014904 60 0.012
mesodermal cell migration GO:0008078 4 0.012
anion transmembrane transport GO:0098656 71 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
inflammatory response GO:0006954 244 0.012
oocyte construction GO:0007308 2 0.012
regulation of protein transport GO:0051223 163 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
ossification GO:0001503 216 0.012
amide transport GO:0042886 138 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
organic acid transport GO:0015849 101 0.012
Mouse
negative regulation of nervous system development GO:0051961 156 0.012
regulation of cellular component size GO:0032535 121 0.012
cell fate commitment GO:0045165 210 0.012
protein localization to membrane GO:0072657 108 0.012
wnt signaling pathway GO:0016055 188 0.012
calcium ion homeostasis GO:0055074 127 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
tissue remodeling GO:0048771 102 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
nuclear import GO:0051170 95 0.012
g protein coupled glutamate receptor signaling pathway GO:0007216 3 0.011
neuromuscular process GO:0050905 99 0.011
regulation of cell growth GO:0001558 91 0.011
myosin filament organization GO:0031033 3 0.011
protein targeting GO:0006605 143 0.011
positive regulation of chemotaxis GO:0050921 38 0.011
generation of precursor metabolites and energy GO:0006091 103 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
substantia nigra development GO:0021762 2 0.011
regulation of binding GO:0051098 111 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
regulation of cell projection assembly GO:0060491 38 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
sodium ion transport GO:0006814 73 0.011
organelle fission GO:0048285 170 0.011
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.011
neuronal action potential GO:0019228 54 0.011
regulation of multi organism process GO:0043900 111 0.011
anatomical structure homeostasis GO:0060249 145 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
cardiac muscle cell contraction GO:0086003 7 0.011
regulation of protein catabolic process GO:0042176 108 0.011
response to radiation GO:0009314 165 0.011
regionalization GO:0003002 337 0.011
positive regulation of cell motility GO:2000147 116 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
amino acid transport GO:0006865 61 0.011
regulation of protein kinase activity GO:0045859 232 0.011
regulation of intracellular transport GO:0032386 159 0.011
cell growth GO:0016049 130 0.011
regulation of response to wounding GO:1903034 189 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
forebrain development GO:0030900 302 0.011
response to lipopolysaccharide GO:0032496 128 0.011
lipid localization GO:0010876 126 0.011
Mouse
leukocyte mediated immunity GO:0002443 174 0.011
positive regulation of gtpase activity GO:0043547 85 0.011
negative regulation of immune system process GO:0002683 209 0.011
rhythmic process GO:0048511 174 0.011
glial cell differentiation GO:0010001 131 0.010
sodium ion transmembrane transport GO:0035725 49 0.010
glucose homeostasis GO:0042593 128 0.010
membrane depolarization GO:0051899 64 0.010
cytokine production GO:0001816 319 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
regulation of anatomical structure size GO:0090066 178 0.010
lipid transport GO:0006869 98 0.010
Mouse
negative regulation of molecular function GO:0044092 258 0.010
cellular protein catabolic process GO:0044257 155 0.010
regulation of ras protein signal transduction GO:0046578 114 0.010
ventricular cardiac muscle cell action potential GO:0086005 4 0.010
immune response regulating signaling pathway GO:0002764 125 0.010
fat cell proliferation GO:0070341 4 0.010
anion transport GO:0006820 177 0.010
Mouse
cellular response to dna damage stimulus GO:0006974 207 0.010
regulation of cytoplasmic transport GO:1903649 112 0.010
canonical wnt signaling pathway GO:0060070 130 0.010
stem cell development GO:0048864 219 0.010
endomembrane system organization GO:0010256 147 0.010
actin filament polymerization GO:0030041 44 0.010
exocytosis GO:0006887 121 0.010

Pla2g4e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
musculoskeletal system disease DOID:17 0 0.018
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
central nervous system disease DOID:331 0 0.011