Mus musculus

0 known processes

Enpp5

ectonucleotide pyrophosphatase/phosphodiesterase 5

(Aliases: AW061004,E-NPP 5,D17Abb1e,KIAA4152,mKIAA4152)

Enpp5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.111
transmembrane transport GO:0055085 412 0.080
cellular amine metabolic process GO:0044106 44 0.055
Mouse
oxidation reduction process GO:0055114 342 0.055
cation transport GO:0006812 399 0.052
cellular lipid metabolic process GO:0044255 323 0.050
ion transmembrane transport GO:0034220 361 0.049
nucleoside phosphate metabolic process GO:0006753 338 0.046
Yeast
regulation of cellular ketone metabolic process GO:0010565 66 0.046
amine metabolic process GO:0009308 45 0.045
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.042
Yeast
regulation of cellular amino acid metabolic process GO:0006521 5 0.041
cellular ketone metabolic process GO:0042180 84 0.038
purine containing compound metabolic process GO:0072521 311 0.038
nucleotide metabolic process GO:0009117 332 0.037
anion transport GO:0006820 177 0.036
macromolecule catabolic process GO:0009057 281 0.036
organic anion transport GO:0015711 137 0.035
male gamete generation GO:0048232 285 0.034
spermatogenesis GO:0007283 284 0.032
regulation of cellular amine metabolic process GO:0033238 20 0.032
glycosyl compound metabolic process GO:1901657 246 0.031
organonitrogen compound catabolic process GO:1901565 264 0.031
inorganic ion transmembrane transport GO:0098660 234 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
purine nucleotide metabolic process GO:0006163 302 0.030
ribonucleoside metabolic process GO:0009119 245 0.030
purine nucleoside metabolic process GO:0042278 241 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.029
nitrogen compound transport GO:0071705 271 0.029
organonitrogen compound biosynthetic process GO:1901566 192 0.029
nucleoside triphosphate metabolic process GO:0009141 230 0.028
Yeast
nucleoside metabolic process GO:0009116 246 0.028
protein catabolic process GO:0030163 221 0.028
lipid biosynthetic process GO:0008610 179 0.027
cellular homeostasis GO:0019725 240 0.027
ribonucleotide metabolic process GO:0009259 291 0.027
response to organonitrogen compound GO:0010243 246 0.027
inorganic cation transmembrane transport GO:0098662 207 0.027
carbohydrate metabolic process GO:0005975 230 0.026
cation transmembrane transport GO:0098655 266 0.026
carbohydrate derivative biosynthetic process GO:1901137 183 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
negative regulation of protein metabolic process GO:0051248 282 0.025
negative regulation of cell proliferation GO:0008285 296 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
organic cyclic compound catabolic process GO:1901361 295 0.024
apoptotic signaling pathway GO:0097190 306 0.024
microtubule based process GO:0007017 236 0.023
regulation of ion transport GO:0043269 215 0.023
small gtpase mediated signal transduction GO:0007264 97 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.023
metal ion homeostasis GO:0055065 189 0.023
regulation of membrane potential GO:0042391 192 0.022
cellular nitrogen compound catabolic process GO:0044270 280 0.022
mapk cascade GO:0000165 281 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
regulation of neuron differentiation GO:0045664 281 0.022
cellular chemical homeostasis GO:0055082 215 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
regulation of organelle organization GO:0033043 289 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.022
carboxylic acid transport GO:0046942 100 0.022
cognition GO:0050890 149 0.022
purine nucleoside catabolic process GO:0006152 205 0.022
cell adhesion GO:0007155 329 0.021
learning or memory GO:0007611 148 0.021
dephosphorylation GO:0016311 129 0.021
nucleoside catabolic process GO:0009164 206 0.021
cation homeostasis GO:0055080 212 0.021
regulation of transferase activity GO:0051338 263 0.021
g protein coupled receptor signaling pathway GO:0007186 243 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
Mouse
response to organic cyclic compound GO:0014070 198 0.020
glycerolipid metabolic process GO:0046486 122 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
aromatic compound catabolic process GO:0019439 286 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
organic acid transport GO:0015849 101 0.020
peptidyl amino acid modification GO:0018193 336 0.020
glycosyl compound catabolic process GO:1901658 206 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
negative regulation of molecular function GO:0044092 258 0.020
sensory perception GO:0007600 245 0.020
heterocycle catabolic process GO:0046700 280 0.019
muscle cell differentiation GO:0042692 261 0.019
divalent metal ion transport GO:0070838 172 0.019
regulation of cell motility GO:2000145 236 0.019
divalent inorganic cation transport GO:0072511 178 0.019
positive regulation of programmed cell death GO:0043068 218 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
synaptic transmission GO:0007268 329 0.019
regulation of purine nucleotide metabolic process GO:1900542 169 0.019
reactive oxygen species metabolic process GO:0072593 84 0.019
amino acid transport GO:0006865 61 0.019
cellular response to acid chemical GO:0071229 68 0.019
fat cell differentiation GO:0045444 160 0.019
nuclear division GO:0000280 158 0.019
ras protein signal transduction GO:0007265 77 0.019
leukocyte differentiation GO:0002521 342 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
cell type specific apoptotic process GO:0097285 268 0.019
intracellular protein transport GO:0006886 204 0.019
regulation of hydrolase activity GO:0051336 246 0.018
protein ubiquitination GO:0016567 171 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
regulation of protein localization GO:0032880 231 0.018
regulation of transmembrane transport GO:0034762 128 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
organophosphate catabolic process GO:0046434 232 0.018
transmission of nerve impulse GO:0019226 76 0.018
sequestering of calcium ion GO:0051208 18 0.018
regulation of mapk cascade GO:0043408 248 0.018
sequestering of metal ion GO:0051238 19 0.018
carboxylic acid biosynthetic process GO:0046394 86 0.018
cellular metal ion homeostasis GO:0006875 151 0.018
membrane organization GO:0061024 245 0.018
organelle fission GO:0048285 170 0.018
purine containing compound catabolic process GO:0072523 213 0.018
cellular ion homeostasis GO:0006873 165 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
cellular protein catabolic process GO:0044257 155 0.017
endocytosis GO:0006897 168 0.017
rho protein signal transduction GO:0007266 32 0.017
cytokine production GO:0001816 319 0.017
germ cell development GO:0007281 185 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
multicellular organismal signaling GO:0035637 91 0.017
l amino acid transport GO:0015807 32 0.017
regulation of cell projection organization GO:0031344 206 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
immune effector process GO:0002252 321 0.017
cytoplasmic transport GO:0016482 234 0.017
actin cytoskeleton organization GO:0030036 220 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
maintenance of location GO:0051235 89 0.017
glycerophospholipid metabolic process GO:0006650 71 0.017
engulfment of apoptotic cell GO:0043652 3 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.016
neuronal action potential GO:0019228 54 0.016
phospholipid metabolic process GO:0006644 87 0.016
regulation of protein catabolic process GO:0042176 108 0.016
myeloid cell differentiation GO:0030099 233 0.016
regulation of homeostatic process GO:0032844 182 0.016
alcohol metabolic process GO:0006066 116 0.016
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
positive regulation of cell development GO:0010720 237 0.016
response to acid chemical GO:0001101 111 0.016
mitochondrion organization GO:0007005 134 0.016
fatty acid metabolic process GO:0006631 121 0.016
striated muscle tissue development GO:0014706 293 0.016
anion transmembrane transport GO:0098656 71 0.016
calcium ion homeostasis GO:0055074 127 0.016
regulation of kinase activity GO:0043549 249 0.016
muscle tissue development GO:0060537 308 0.015
regulation of hormone levels GO:0010817 211 0.015
cellular modified amino acid metabolic process GO:0006575 63 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
sulfur compound metabolic process GO:0006790 100 0.015
organic acid biosynthetic process GO:0016053 86 0.015
anatomical structure homeostasis GO:0060249 145 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
homeostasis of number of cells GO:0048872 210 0.015
positive regulation of cell death GO:0010942 224 0.015
gtp metabolic process GO:0046039 144 0.015
regulation of cell cycle GO:0051726 281 0.015
forebrain development GO:0030900 302 0.015
microtubule cytoskeleton organization GO:0000226 157 0.015
axonogenesis GO:0007409 274 0.015
regulation of secretion GO:0051046 274 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
negative regulation of cell development GO:0010721 169 0.014
regulation of metal ion transport GO:0010959 106 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
protein maturation GO:0051604 176 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
mitotic cell cycle GO:0000278 195 0.014
sensory organ morphogenesis GO:0090596 242 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
rna processing GO:0006396 105 0.014
protein localization to organelle GO:0033365 185 0.014
skeletal muscle organ development GO:0060538 163 0.014
cellular response to lipid GO:0071396 145 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
acetate metabolic process GO:0006083 1 0.014
blood circulation GO:0008015 195 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
response to oxidative stress GO:0006979 123 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
developmental maturation GO:0021700 193 0.014
nucleotide catabolic process GO:0009166 217 0.014
adult behavior GO:0030534 135 0.014
dna metabolic process GO:0006259 303 0.014
endomembrane system organization GO:0010256 147 0.013
small molecule biosynthetic process GO:0044283 132 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
calcium ion transport GO:0006816 159 0.013
regulation of neuron projection development GO:0010975 169 0.013
glycoprotein metabolic process GO:0009100 116 0.013
protein processing GO:0016485 163 0.013
alpha amino acid metabolic process GO:1901605 59 0.013
steroid metabolic process GO:0008202 119 0.013
inflammatory response GO:0006954 244 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
regulation of cell migration GO:0030334 219 0.013
telencephalon development GO:0021537 186 0.013
positive regulation of nervous system development GO:0051962 221 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
nucleoside phosphate biosynthetic process GO:1901293 79 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
cellular calcium ion homeostasis GO:0006874 119 0.013
protein targeting GO:0006605 143 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.013
regulation of cell activation GO:0050865 289 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
organelle localization GO:0051640 179 0.013
regulation of binding GO:0051098 111 0.013
regulation of response to wounding GO:1903034 189 0.013
gland development GO:0048732 330 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
negative regulation of nervous system development GO:0051961 156 0.013
spermatid differentiation GO:0048515 115 0.013
chemotaxis GO:0006935 247 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
cellular alcohol metabolic process GO:0044107 3 0.012
regulation of secretion by cell GO:1903530 249 0.012
regulation of intracellular transport GO:0032386 159 0.012
cell activation involved in immune response GO:0002263 126 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
action potential GO:0001508 78 0.012
positive regulation of protein modification process GO:0031401 299 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
generation of precursor metabolites and energy GO:0006091 103 0.012
methylation GO:0032259 134 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
regulation of cytokine production GO:0001817 266 0.012
calcium ion transmembrane transport GO:0070588 85 0.012
response to light stimulus GO:0009416 135 0.012
spermatid development GO:0007286 108 0.012
translation GO:0006412 93 0.012
cofactor metabolic process GO:0051186 80 0.012
regulation of protein kinase activity GO:0045859 232 0.012
regulation of protein transport GO:0051223 163 0.012
mitochondrion distribution GO:0048311 4 0.012
mrna metabolic process GO:0016071 84 0.012
t cell activation GO:0042110 289 0.012
neuron death GO:0070997 154 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
memory GO:0007613 58 0.012
tissue homeostasis GO:0001894 115 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
striated muscle myosin thick filament assembly GO:0071688 1 0.012
response to inorganic substance GO:0010035 96 0.012
protein localization to membrane GO:0072657 108 0.012
ossification GO:0001503 216 0.012
leukocyte migration GO:0050900 124 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
nucleocytoplasmic transport GO:0006913 139 0.011
wound healing GO:0042060 157 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
locomotory behavior GO:0007626 195 0.011
asymmetric stem cell division GO:0098722 3 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
rhythmic process GO:0048511 174 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
exocytosis GO:0006887 121 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
glucose homeostasis GO:0042593 128 0.011
response to growth factor GO:0070848 198 0.011
cellular amide metabolic process GO:0043603 58 0.011
fatty acid derivative metabolic process GO:1901568 33 0.011
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
limb morphogenesis GO:0035108 149 0.011
regulation of body fluid levels GO:0050878 162 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
regulation of system process GO:0044057 200 0.011
rhodopsin mediated signaling pathway GO:0016056 4 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
regulation of defense response GO:0031347 233 0.011
response to peptide hormone GO:0043434 127 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
intracellular mrna localization GO:0008298 4 0.011
multi multicellular organism process GO:0044706 109 0.011
plasma membrane organization GO:0007009 90 0.011
cellularization GO:0007349 1 0.011
response to peptide GO:1901652 136 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
sodium ion transport GO:0006814 73 0.011
inclusion body assembly GO:0070841 3 0.011
regulation of transporter activity GO:0032409 57 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
membrane lipid metabolic process GO:0006643 53 0.011
positive regulation of transferase activity GO:0051347 167 0.011
cellular protein complex assembly GO:0043623 116 0.011
mitotic cell cycle process GO:1903047 159 0.011
oocyte construction GO:0007308 2 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
regulation of proteolysis GO:0030162 164 0.011
regulation of circadian sleep wake cycle GO:0042749 3 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
camera type eye development GO:0043010 266 0.011
digestive system development GO:0055123 200 0.011
nuclear transport GO:0051169 139 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
macromolecule methylation GO:0043414 120 0.010
blood vessel morphogenesis GO:0048514 285 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
purine nucleoside monophosphate metabolic process GO:0009126 81 0.010
myeloid cell homeostasis GO:0002262 114 0.010
lymphocyte activation involved in immune response GO:0002285 93 0.010
carbohydrate homeostasis GO:0033500 128 0.010
wnt signaling pathway GO:0016055 188 0.010
peptidyl tyrosine modification GO:0018212 145 0.010
positive regulation of cellular catabolic process GO:0031331 148 0.010
pole plasm assembly GO:0007315 2 0.010
regulation of purine nucleotide catabolic process GO:0033121 122 0.010
ubiquitin dependent protein catabolic process GO:0006511 129 0.010
regulation of inflammatory response GO:0050727 147 0.010
oocyte axis specification GO:0007309 2 0.010
cell maturation GO:0048469 127 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
circulatory system process GO:0003013 197 0.010
response to lipopolysaccharide GO:0032496 128 0.010
atp metabolic process GO:0046034 75 0.010
epithelial cell proliferation GO:0050673 174 0.010
sphingolipid metabolic process GO:0006665 45 0.010
ear development GO:0043583 200 0.010
muscle contraction GO:0006936 101 0.010
lipid transport GO:0006869 98 0.010
positive regulation of secretion GO:0051047 130 0.010
cell substrate adhesion GO:0031589 130 0.010
lateral inhibition GO:0046331 1 0.010
regulation of cell adhesion GO:0030155 154 0.010
response to radiation GO:0009314 165 0.010
peptidyl tyrosine phosphorylation GO:0018108 143 0.010
peptide metabolic process GO:0006518 46 0.010
compound eye development GO:0048749 1 0.010
progesterone metabolic process GO:0042448 4 0.010
cellular amino acid catabolic process GO:0009063 25 0.010
regulation of engulfment of apoptotic cell GO:1901074 2 0.010
neuron apoptotic process GO:0051402 142 0.010

Enpp5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.036
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
central nervous system disease DOID:331 0 0.022
inherited metabolic disorder DOID:655 0 0.019
immune system disease DOID:2914 0 0.014
hematopoietic system disease DOID:74 0 0.014
sensory system disease DOID:0050155 0 0.012
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011
eye and adnexa disease DOID:1492 0 0.011