Mus musculus

103 known processes

Enpp1

ectonucleotide pyrophosphatase/phosphodiesterase 1

(Aliases: Pca-1,Pca,Pdnp1,AI428932,C76301,PC-1,ttw,Npps,E-NPP1,M6S1,twy,Ly-41,NPP1,4833416E15Rik,CD203c)

Enpp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glycosyl compound catabolic process GO:1901658 206 0.181
transmembrane transport GO:0055085 412 0.156
amine metabolic process GO:0009308 45 0.111
Mouse
nucleoside catabolic process GO:0009164 206 0.091
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.089
purine nucleoside catabolic process GO:0006152 205 0.084
organonitrogen compound catabolic process GO:1901565 264 0.080
nucleobase containing small molecule metabolic process GO:0055086 352 0.079
aromatic compound catabolic process GO:0019439 286 0.078
carbohydrate derivative catabolic process GO:1901136 231 0.078
peptidyl amino acid modification GO:0018193 336 0.077
organic anion transport GO:0015711 137 0.075
apoptotic signaling pathway GO:0097190 306 0.074
glycosyl compound metabolic process GO:1901657 246 0.071
carbohydrate derivative biosynthetic process GO:1901137 183 0.071
ribonucleoside catabolic process GO:0042454 206 0.068
regulation of cellular ketone metabolic process GO:0010565 66 0.068
purine ribonucleoside metabolic process GO:0046128 241 0.067
nucleoside phosphate catabolic process GO:1901292 222 0.064
carboxylic acid transport GO:0046942 100 0.064
regulation of hydrolase activity GO:0051336 246 0.062
regulation of cellular amine metabolic process GO:0033238 20 0.062
cellular chemical homeostasis GO:0055082 215 0.060
Human
protein catabolic process GO:0030163 221 0.060
cellular ketone metabolic process GO:0042180 84 0.057
regulation of secretion by cell GO:1903530 249 0.057
ribonucleotide catabolic process GO:0009261 208 0.056
nucleoside metabolic process GO:0009116 246 0.055
organic acid transport GO:0015849 101 0.055
heterocycle catabolic process GO:0046700 280 0.052
nucleoside triphosphate metabolic process GO:0009141 230 0.051
cytokine production GO:0001816 319 0.050
organic hydroxy compound metabolic process GO:1901615 203 0.049
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.049
vacuole organization GO:0007033 38 0.048
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.048
oxidation reduction process GO:0055114 342 0.048
Human
cellular lipid metabolic process GO:0044255 323 0.047
Mouse
purine nucleotide metabolic process GO:0006163 302 0.047
regulation of ossification GO:0030278 112 0.047
glycoprotein metabolic process GO:0009100 116 0.046
negative regulation of protein metabolic process GO:0051248 282 0.045
Human
nucleoside phosphate metabolic process GO:0006753 338 0.045
macromolecule catabolic process GO:0009057 281 0.045
anion transport GO:0006820 177 0.044
Human
ribonucleotide metabolic process GO:0009259 291 0.044
ribose phosphate metabolic process GO:0019693 291 0.044
regulation of cytokine production GO:0001817 266 0.043
cellular nitrogen compound catabolic process GO:0044270 280 0.043
purine ribonucleoside catabolic process GO:0046130 205 0.043
ribonucleoside triphosphate metabolic process GO:0009199 220 0.043
organonitrogen compound biosynthetic process GO:1901566 192 0.042
mapk cascade GO:0000165 281 0.042
cation transmembrane transport GO:0098655 266 0.042
purine nucleoside triphosphate metabolic process GO:0009144 226 0.042
positive regulation of defense response GO:0031349 124 0.041
purine nucleoside metabolic process GO:0042278 241 0.041
nucleoside monophosphate metabolic process GO:0009123 85 0.041
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.040
Human
regulation of ion transport GO:0043269 215 0.040
nucleotide catabolic process GO:0009166 217 0.040
nucleotide metabolic process GO:0009117 332 0.039
regulation of response to wounding GO:1903034 189 0.039
regulation of neuron projection development GO:0010975 169 0.039
purine nucleoside triphosphate catabolic process GO:0009146 203 0.039
cell adhesion GO:0007155 329 0.039
macromolecule glycosylation GO:0043413 55 0.039
immune effector process GO:0002252 321 0.039
regulation of defense response GO:0031347 233 0.038
protein maturation GO:0051604 176 0.038
nucleoside triphosphate catabolic process GO:0009143 205 0.038
regulation of anatomical structure size GO:0090066 178 0.038
regulation of transferase activity GO:0051338 263 0.038
rho protein signal transduction GO:0007266 32 0.038
positive regulation of cellular amine metabolic process GO:0033240 5 0.038
regulation of cellular amino acid metabolic process GO:0006521 5 0.038
membrane organization GO:0061024 245 0.038
inflammatory response GO:0006954 244 0.038
cellular amino acid metabolic process GO:0006520 103 0.037
regulation of apoptotic signaling pathway GO:2001233 197 0.036
cellular homeostasis GO:0019725 240 0.036
Human
negative regulation of phosphorylation GO:0042326 166 0.036
Human
synaptic transmission GO:0007268 329 0.036
response to molecule of bacterial origin GO:0002237 143 0.036
ion transmembrane transport GO:0034220 361 0.035
reactive oxygen species biosynthetic process GO:1903409 8 0.034
gland development GO:0048732 330 0.034
response to nutrient levels GO:0031667 109 0.033
ribonucleoside triphosphate catabolic process GO:0009203 199 0.033
positive regulation of protein modification process GO:0031401 299 0.033
small gtpase mediated signal transduction GO:0007264 97 0.033
cellular divalent inorganic cation homeostasis GO:0072503 127 0.033
cation homeostasis GO:0055080 212 0.033
ribonucleoside metabolic process GO:0009119 245 0.033
t cell activation GO:0042110 289 0.032
ras protein signal transduction GO:0007265 77 0.032
muscle tissue development GO:0060537 308 0.032
male gamete generation GO:0048232 285 0.032
negative regulation of protein modification process GO:0031400 163 0.031
Human
divalent inorganic cation transport GO:0072511 178 0.031
cellular macromolecule catabolic process GO:0044265 206 0.031
response to extracellular stimulus GO:0009991 127 0.031
purine containing compound metabolic process GO:0072521 311 0.031
ossification GO:0001503 216 0.031
carbohydrate metabolic process GO:0005975 230 0.031
Human
protein modification by small protein conjugation or removal GO:0070647 207 0.031
regulation of neuron differentiation GO:0045664 281 0.031
regulation of organelle organization GO:0033043 289 0.031
reactive nitrogen species metabolic process GO:2001057 0 0.030
circulatory system process GO:0003013 197 0.030
protein glycosylation GO:0006486 55 0.030
cellular ion homeostasis GO:0006873 165 0.030
Human
muscle system process GO:0003012 141 0.030
regulation of muscle system process GO:0090257 80 0.030
regulation of secretion GO:0051046 274 0.030
positive regulation of protein phosphorylation GO:0001934 242 0.030
leukocyte mediated immunity GO:0002443 174 0.029
regulation of membrane potential GO:0042391 192 0.029
sensory perception GO:0007600 245 0.029
regulation of inflammatory response GO:0050727 147 0.029
divalent inorganic cation homeostasis GO:0072507 138 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.029
intracellular protein transport GO:0006886 204 0.029
developmental maturation GO:0021700 193 0.029
extrinsic apoptotic signaling pathway GO:0097191 126 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.028
Human
negative regulation of phosphorus metabolic process GO:0010563 184 0.028
Human
striated muscle tissue development GO:0014706 293 0.028
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.028
cellular amine metabolic process GO:0044106 44 0.028
Mouse
glucose homeostasis GO:0042593 128 0.028
innate immune response GO:0045087 157 0.028
regulation of nucleotide metabolic process GO:0006140 169 0.027
protein processing GO:0016485 163 0.027
glycosylation GO:0070085 62 0.027
angiogenesis GO:0001525 201 0.027
transmission of nerve impulse GO:0019226 76 0.027
skeletal system development GO:0001501 356 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
Human
organelle localization GO:0051640 179 0.027
purine ribonucleotide catabolic process GO:0009154 208 0.027
regulation of intracellular transport GO:0032386 159 0.027
cellular response to lipid GO:0071396 145 0.027
negative regulation of intracellular signal transduction GO:1902532 167 0.027
organic cyclic compound catabolic process GO:1901361 295 0.026
nitrogen compound transport GO:0071705 271 0.026
sulfur compound metabolic process GO:0006790 100 0.026
Human
regulation of protein localization GO:0032880 231 0.026
wound healing GO:0042060 157 0.026
cellular protein catabolic process GO:0044257 155 0.026
regulation of establishment of protein localization GO:0070201 181 0.026
hemostasis GO:0007599 78 0.026
organic hydroxy compound transport GO:0015850 93 0.026
purine nucleotide catabolic process GO:0006195 211 0.026
response to organonitrogen compound GO:0010243 246 0.026
Human
regulation of mapk cascade GO:0043408 248 0.026
blood coagulation GO:0007596 76 0.025
carbohydrate homeostasis GO:0033500 128 0.025
wnt signaling pathway GO:0016055 188 0.025
calcium ion homeostasis GO:0055074 127 0.025
positive regulation of hydrolase activity GO:0051345 148 0.025
axonogenesis GO:0007409 274 0.025
regulation of system process GO:0044057 200 0.025
cell substrate adhesion GO:0031589 130 0.025
neurotransmitter transport GO:0006836 76 0.025
lymphocyte mediated immunity GO:0002449 139 0.025
regulation of protein serine threonine kinase activity GO:0071900 157 0.025
regulation of purine nucleotide metabolic process GO:1900542 169 0.025
negative regulation of molecular function GO:0044092 258 0.025
morphogenesis of a branching structure GO:0001763 203 0.024
glycoprotein biosynthetic process GO:0009101 89 0.024
muscle contraction GO:0006936 101 0.024
leukocyte differentiation GO:0002521 342 0.024
cell activation involved in immune response GO:0002263 126 0.024
response to organic cyclic compound GO:0014070 198 0.024
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.024
developmental growth involved in morphogenesis GO:0060560 138 0.024
regulation of kinase activity GO:0043549 249 0.024
response to inorganic substance GO:0010035 96 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.024
cellular modified amino acid metabolic process GO:0006575 63 0.024
biomineral tissue development GO:0031214 64 0.023
positive regulation of cellular catabolic process GO:0031331 148 0.023
positive regulation of apoptotic process GO:0043065 217 0.023
blood vessel morphogenesis GO:0048514 285 0.023
inorganic cation transmembrane transport GO:0098662 207 0.023
regulation of cellular response to stress GO:0080135 159 0.023
cognition GO:0050890 149 0.023
amide transport GO:0042886 138 0.022
cellular response to molecule of bacterial origin GO:0071219 83 0.022
ribonucleoside monophosphate metabolic process GO:0009161 80 0.022
divalent metal ion transport GO:0070838 172 0.022
regulation of cell adhesion GO:0030155 154 0.022
cellular amide metabolic process GO:0043603 58 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
endocytosis GO:0006897 168 0.022
engulfment of apoptotic cell GO:0043652 3 0.022
metal ion homeostasis GO:0055065 189 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.022
positive regulation of mapk cascade GO:0043410 170 0.022
maintenance of location GO:0051235 89 0.022
Human
lipid transport GO:0006869 98 0.022
cytoplasmic transport GO:0016482 234 0.022
extracellular matrix organization GO:0030198 147 0.021
purine containing compound catabolic process GO:0072523 213 0.021
leukocyte mediated cytotoxicity GO:0001909 62 0.021
positive regulation of transferase activity GO:0051347 167 0.021
interleukin 8 production GO:0032637 4 0.021
response to acid chemical GO:0001101 111 0.021
stem cell differentiation GO:0048863 268 0.021
renal system development GO:0072001 225 0.021
positive regulation of cytokine production GO:0001819 174 0.020
response to lipopolysaccharide GO:0032496 128 0.020
small molecule biosynthetic process GO:0044283 132 0.020
endomembrane system organization GO:0010256 147 0.020
peptide metabolic process GO:0006518 46 0.020
regulation of protein kinase activity GO:0045859 232 0.020
cellular response to lipopolysaccharide GO:0071222 77 0.020
regulation of interleukin 8 production GO:0032677 3 0.020
detection of stimulus GO:0051606 84 0.020
positive regulation of proteolysis GO:0045862 85 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.020
regulation of proteolysis GO:0030162 164 0.020
ribonucleoside monophosphate catabolic process GO:0009158 57 0.020
regulation of protein catabolic process GO:0042176 108 0.019
adaptive immune response GO:0002250 155 0.019
inorganic ion transmembrane transport GO:0098660 234 0.019
cellular metal ion homeostasis GO:0006875 151 0.019
neuronal action potential GO:0019228 54 0.019
regulation of cellular component size GO:0032535 121 0.019
nuclear transport GO:0051169 139 0.019
protein localization to nucleus GO:0034504 121 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
regulation of protein transport GO:0051223 163 0.019
response to hypoxia GO:0001666 58 0.019
anatomical structure homeostasis GO:0060249 145 0.019
myeloid cell differentiation GO:0030099 233 0.018
regulation of cell projection organization GO:0031344 206 0.018
stem cell development GO:0048864 219 0.018
response to oxygen levels GO:0070482 62 0.018
exocytosis GO:0006887 121 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
sequestering of metal ion GO:0051238 19 0.018
dephosphorylation GO:0016311 129 0.018
regulation of wnt signaling pathway GO:0030111 123 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
g protein coupled receptor signaling pathway GO:0007186 243 0.018
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.018
amino acid transport GO:0006865 61 0.018
regulation of homeostatic process GO:0032844 182 0.018
positive regulation of gtpase activity GO:0043547 85 0.018
hormone secretion GO:0046879 128 0.018
epithelial cell development GO:0002064 159 0.018
guanosine containing compound catabolic process GO:1901069 144 0.017
sphingolipid metabolic process GO:0006665 45 0.017
regulation of lipid metabolic process GO:0019216 118 0.017
regulation of purine nucleotide catabolic process GO:0033121 122 0.017
positive regulation of cell development GO:0010720 237 0.017
blood circulation GO:0008015 195 0.017
interleukin 8 secretion GO:0072606 3 0.017
positive regulation of apoptotic signaling pathway GO:2001235 95 0.017
cellular response to external stimulus GO:0071496 88 0.017
cellular response to extracellular stimulus GO:0031668 81 0.017
urogenital system development GO:0001655 261 0.017
regulation of actin filament based process GO:0032970 99 0.017
tissue remodeling GO:0048771 102 0.017
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.017
cellular response to dna damage stimulus GO:0006974 207 0.017
spermatogenesis GO:0007283 284 0.017
gtp metabolic process GO:0046039 144 0.017
epithelial tube morphogenesis GO:0060562 303 0.017
lymphocyte differentiation GO:0030098 242 0.017
muscle cell differentiation GO:0042692 261 0.017
regulation of interleukin 8 secretion GO:2000482 2 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
morphogenesis of a branching epithelium GO:0061138 193 0.017
phagocytosis GO:0006909 66 0.017
neuron migration GO:0001764 122 0.017
multi multicellular organism process GO:0044706 109 0.017
rhythmic process GO:0048511 174 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
Human
homeostasis of number of cells GO:0048872 210 0.017
skeletal muscle organ development GO:0060538 163 0.017
regulation of ketone biosynthetic process GO:0010566 2 0.016
cell type specific apoptotic process GO:0097285 268 0.016
regulation of hormone levels GO:0010817 211 0.016
response to growth factor GO:0070848 198 0.016
regulation of bone mineralization GO:0030500 31 0.016
learning or memory GO:0007611 148 0.016
forebrain development GO:0030900 302 0.016
protein o linked glycosylation GO:0006493 16 0.016
response to starvation GO:0042594 65 0.016
establishment of protein localization to organelle GO:0072594 118 0.016
peptide hormone secretion GO:0030072 109 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.016
regulation of ras protein signal transduction GO:0046578 114 0.016
sequestering of calcium ion GO:0051208 18 0.016
lymphocyte proliferation GO:0046651 164 0.016
peptidyl serine modification GO:0018209 83 0.016
dicarboxylic acid transport GO:0006835 29 0.016
dendrite development GO:0016358 115 0.016
sulfur compound biosynthetic process GO:0044272 37 0.016
bone remodeling GO:0046849 53 0.015
multicellular organismal signaling GO:0035637 91 0.015
camera type eye development GO:0043010 266 0.015
protein targeting GO:0006605 143 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
positive regulation of cell death GO:0010942 224 0.015
t cell differentiation GO:0030217 174 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
calcium ion transport GO:0006816 159 0.015
protein secretion GO:0009306 111 0.015
lymphocyte activation involved in immune response GO:0002285 93 0.015
regulation of blood pressure GO:0008217 93 0.015
protein localization to organelle GO:0033365 185 0.015
cellular response to nutrient levels GO:0031669 64 0.015
regionalization GO:0003002 337 0.015
regulation of nucleotide catabolic process GO:0030811 122 0.015
cell growth GO:0016049 130 0.015
Human
ceramide metabolic process GO:0006672 31 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
chemotaxis GO:0006935 247 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
regulation of neurotransmitter levels GO:0001505 87 0.015
extracellular structure organization GO:0043062 148 0.015
gtp catabolic process GO:0006184 143 0.015
negative regulation of response to wounding GO:1903035 77 0.015
regulation of cell cycle GO:0051726 281 0.015
amino acid transmembrane transport GO:0003333 37 0.015
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.015
neuron death GO:0070997 154 0.015
regulation of cell growth GO:0001558 91 0.015
Human
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.015
lytic vacuole organization GO:0080171 21 0.014
positive regulation of innate immune response GO:0045089 80 0.014
positive regulation of kinase activity GO:0033674 155 0.014
t cell mediated cytotoxicity GO:0001913 26 0.014
establishment of vesicle localization GO:0051650 81 0.014
epithelial cell proliferation GO:0050673 174 0.014
t cell differentiation in thymus GO:0033077 77 0.014
memory GO:0007613 58 0.014
tissue homeostasis GO:0001894 115 0.014
cellular response to starvation GO:0009267 57 0.014
regulation of endopeptidase activity GO:0052548 89 0.014
kidney development GO:0001822 213 0.014
respiratory tube development GO:0030323 167 0.014
regulation of hormone secretion GO:0046883 88 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.014
positive regulation of interleukin 8 production GO:0032757 2 0.014
canonical wnt signaling pathway GO:0060070 130 0.014
cation transport GO:0006812 399 0.014
transition metal ion transport GO:0000041 38 0.014
interleukin 6 production GO:0032635 58 0.014
monocarboxylic acid transport GO:0015718 44 0.014
leukocyte activation involved in immune response GO:0002366 126 0.014
coagulation GO:0050817 78 0.014
placenta development GO:0001890 140 0.014
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.014
digestive tract development GO:0048565 190 0.014
proteoglycan metabolic process GO:0006029 38 0.014
negative regulation of secretion GO:0051048 61 0.014
neuron projection extension GO:1990138 64 0.014
organelle assembly GO:0070925 177 0.014
actin cytoskeleton organization GO:0030036 220 0.014
peptide transport GO:0015833 133 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
response to metal ion GO:0010038 47 0.013
response to transforming growth factor beta GO:0071559 88 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
action potential GO:0001508 78 0.013
regulation of transmembrane transport GO:0034762 128 0.013
phospholipid transfer to membrane GO:0006649 2 0.013
regulation of cell size GO:0008361 72 0.013
acute inflammatory response GO:0002526 41 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
Human
sensory organ morphogenesis GO:0090596 242 0.013
negative regulation of cytokine production GO:0001818 84 0.013
oocyte axis specification GO:0007309 2 0.013
regulation of nucleoside metabolic process GO:0009118 130 0.013
peptide secretion GO:0002790 114 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.013
maintenance of cell number GO:0098727 3 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
regulation of muscle contraction GO:0006937 49 0.013
plasma membrane organization GO:0007009 90 0.013
respiratory system development GO:0060541 190 0.013
cell killing GO:0001906 67 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
compound eye development GO:0048749 1 0.013
cellular calcium ion homeostasis GO:0006874 119 0.013
hormone metabolic process GO:0042445 86 0.013
positive regulation of vasoconstriction GO:0045907 4 0.013
regulation of cell motility GO:2000145 236 0.013
skin development GO:0043588 220 0.013
membrane lipid metabolic process GO:0006643 53 0.013
synaptic vesicle localization GO:0097479 59 0.013
positive regulation of nervous system development GO:0051962 221 0.013
positive regulation of secretion GO:0051047 130 0.012
regulation of cell activation GO:0050865 289 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
negative regulation of cell cycle GO:0045786 123 0.012
negative regulation of phospholipase activity GO:0010519 4 0.012
cytosolic calcium ion homeostasis GO:0051480 70 0.012
mitochondrion organization GO:0007005 134 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
neurotransmitter secretion GO:0007269 62 0.012
multicellular organism growth GO:0035264 161 0.012
myeloid cell homeostasis GO:0002262 114 0.012
regulation of biomineral tissue development GO:0070167 33 0.012
regulation of body fluid levels GO:0050878 162 0.012
organophosphate catabolic process GO:0046434 232 0.012
regulation of peptidase activity GO:0052547 96 0.012
cofactor transport GO:0051181 4 0.012
ear development GO:0043583 200 0.012
negative regulation of immune system process GO:0002683 209 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
response to oxidative stress GO:0006979 123 0.012
smooth muscle contraction GO:0006939 44 0.012
negative regulation of cell development GO:0010721 169 0.012
l amino acid transport GO:0015807 32 0.012
locomotory behavior GO:0007626 195 0.012
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.012
lipid localization GO:0010876 126 0.012
Human
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
membrane depolarization GO:0051899 64 0.012
lysosome organization GO:0007040 21 0.012
regulation of cell migration GO:0030334 219 0.012
nuclear import GO:0051170 95 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
regulation of protein secretion GO:0050708 82 0.012
negative regulation of transferase activity GO:0051348 85 0.012
dna endoreduplication GO:0042023 4 0.011
defense response to other organism GO:0098542 197 0.011
regulation of axon extension GO:0030516 43 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
response to peptide GO:1901652 136 0.011
Human
adult locomotory behavior GO:0008344 91 0.011
regulation of interleukin 6 production GO:0032675 55 0.011
defense response to bacterium GO:0042742 119 0.011
anion transmembrane transport GO:0098656 71 0.011
bone development GO:0060348 120 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
leukocyte migration GO:0050900 124 0.011
protein ubiquitination GO:0016567 171 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
positive regulation of protein transport GO:0051222 93 0.011
lipid biosynthetic process GO:0008610 179 0.011
connective tissue development GO:0061448 179 0.011
regulation of phospholipase a2 activity GO:0032429 3 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
synapse organization GO:0050808 125 0.011
t cell mediated immunity GO:0002456 50 0.011
regulation of actin cytoskeleton organization GO:0032956 84 0.011
ameboidal type cell migration GO:0001667 128 0.011
atp catabolic process GO:0006200 55 0.011
positive regulation of immune effector process GO:0002699 107 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
negative regulation of secretion by cell GO:1903531 54 0.011
signal transduction in absence of ligand GO:0038034 55 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
regulation of protein processing GO:0070613 96 0.011
fatty acid metabolic process GO:0006631 121 0.011
leukocyte apoptotic process GO:0071887 71 0.011
retrograde transport endosome to golgi GO:0042147 2 0.011
regulation of endocytosis GO:0030100 69 0.011
leukocyte proliferation GO:0070661 172 0.011
phagolysosome assembly GO:0001845 3 0.011
digestive system development GO:0055123 200 0.011
positive regulation of phagocytosis engulfment GO:0060100 3 0.011

Enpp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.071
Human
nervous system disease DOID:863 0 0.071
immune system disease DOID:2914 0 0.061
disease of metabolism DOID:0014667 0 0.038
Human
inherited metabolic disorder DOID:655 0 0.038
Human
musculoskeletal system disease DOID:17 0 0.028
central nervous system disease DOID:331 0 0.025
sensory system disease DOID:0050155 0 0.022
hematopoietic system disease DOID:74 0 0.019
bone disease DOID:0080001 0 0.018
connective tissue disease DOID:65 0 0.018
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
vascular disease DOID:178 0 0.014
Human
cardiovascular system disease DOID:1287 0 0.014
Human
retinal disease DOID:5679 0 0.013
retinal degeneration DOID:8466 0 0.013
neurodegenerative disease DOID:1289 0 0.011