Mus musculus

50 known processes

Fndc3a

fibronectin type III domain containing 3A

(Aliases: sys,F730017H24Rik,D14Ertd453e,1700094E19Rik,Fndc3)

Fndc3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecule catabolic process GO:0009057 281 0.201
small gtpase mediated signal transduction GO:0007264 97 0.193
modification dependent macromolecule catabolic process GO:0043632 133 0.154
response to topologically incorrect protein GO:0035966 25 0.150
regulation of nucleoside metabolic process GO:0009118 130 0.144
transmembrane transport GO:0055085 412 0.126
t cell activation GO:0042110 289 0.121
heterocycle catabolic process GO:0046700 280 0.112
positive regulation of cytokine production GO:0001819 174 0.109
positive regulation of cellular catabolic process GO:0031331 148 0.105
cellular macromolecule catabolic process GO:0044265 206 0.088
carbohydrate derivative catabolic process GO:1901136 231 0.082
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.079
cellular response to topologically incorrect protein GO:0035967 25 0.077
response to endoplasmic reticulum stress GO:0034976 53 0.073
spermatogenesis GO:0007283 284 0.072
aromatic compound catabolic process GO:0019439 286 0.071
purine ribonucleoside metabolic process GO:0046128 241 0.070
regulation of lymphocyte activation GO:0051249 240 0.069
ribonucleoside metabolic process GO:0009119 245 0.067
ras protein signal transduction GO:0007265 77 0.066
ubiquitin dependent protein catabolic process GO:0006511 129 0.066
regulation of nucleotide metabolic process GO:0006140 169 0.065
cellular nitrogen compound catabolic process GO:0044270 280 0.065
protein catabolic process GO:0030163 221 0.064
cytoplasmic transport GO:0016482 234 0.063
cation transport GO:0006812 399 0.061
organic cyclic compound catabolic process GO:1901361 295 0.060
ribonucleoside triphosphate catabolic process GO:0009203 199 0.059
response to lipopolysaccharide GO:0032496 128 0.058
modification dependent protein catabolic process GO:0019941 133 0.058
regulation of cellular catabolic process GO:0031329 242 0.058
response to unfolded protein GO:0006986 21 0.055
regulation of t cell activation GO:0050863 170 0.054
purine nucleoside metabolic process GO:0042278 241 0.053
regulation of hydrolase activity GO:0051336 246 0.052
positive regulation of hydrolase activity GO:0051345 148 0.051
er nucleus signaling pathway GO:0006984 27 0.049
translation GO:0006412 93 0.048
regulation of purine nucleotide metabolic process GO:1900542 169 0.046
nucleoside phosphate catabolic process GO:1901292 222 0.046
endoplasmic reticulum unfolded protein response GO:0030968 19 0.046
cytokine production GO:0001816 319 0.045
purine containing compound catabolic process GO:0072523 213 0.044
cell type specific apoptotic process GO:0097285 268 0.044
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.041
regulation of cell activation GO:0050865 289 0.041
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.040
rab protein signal transduction GO:0032482 1 0.040
epidermis development GO:0008544 187 0.039
regulation of ion transport GO:0043269 215 0.039
negative regulation of cell proliferation GO:0008285 296 0.039
leukocyte proliferation GO:0070661 172 0.039
positive regulation of lymphocyte activation GO:0051251 140 0.038
leukocyte differentiation GO:0002521 342 0.037
nucleoside metabolic process GO:0009116 246 0.037
t cell proliferation GO:0042098 120 0.037
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.037
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
skin development GO:0043588 220 0.036
lymphocyte proliferation GO:0046651 164 0.036
regulation of body fluid levels GO:0050878 162 0.036
cellular response to biotic stimulus GO:0071216 92 0.036
homeostasis of number of cells GO:0048872 210 0.035
nucleoside phosphate metabolic process GO:0006753 338 0.035
protein modification by small protein conjugation GO:0032446 187 0.035
organophosphate catabolic process GO:0046434 232 0.035
regulation of defense response GO:0031347 233 0.034
amine metabolic process GO:0009308 45 0.034
positive regulation of protein phosphorylation GO:0001934 242 0.034
glycoprotein metabolic process GO:0009100 116 0.034
male gamete generation GO:0048232 285 0.034
epithelial cell development GO:0002064 159 0.034
purine nucleotide metabolic process GO:0006163 302 0.034
response to extracellular stimulus GO:0009991 127 0.033
cellular amine metabolic process GO:0044106 44 0.033
positive regulation of leukocyte differentiation GO:1902107 86 0.032
regulation of leukocyte differentiation GO:1902105 159 0.032
purine nucleoside triphosphate catabolic process GO:0009146 203 0.032
metal ion homeostasis GO:0055065 189 0.032
positive regulation of protein modification process GO:0031401 299 0.032
embryonic epithelial tube formation GO:0001838 130 0.031
positive regulation of nucleotide metabolic process GO:0045981 114 0.031
negative regulation of protein metabolic process GO:0051248 282 0.031
spermatid differentiation GO:0048515 115 0.031
cellular response to molecule of bacterial origin GO:0071219 83 0.031
purine nucleoside catabolic process GO:0006152 205 0.031
regulation of secretion by cell GO:1903530 249 0.031
carbohydrate derivative biosynthetic process GO:1901137 183 0.031
cellular protein catabolic process GO:0044257 155 0.031
cellular homeostasis GO:0019725 240 0.030
ion transmembrane transport GO:0034220 361 0.030
positive regulation of nucleotide catabolic process GO:0030813 88 0.030
purine ribonucleotide catabolic process GO:0009154 208 0.030
vesicle organization GO:0016050 60 0.030
ribonucleoside triphosphate metabolic process GO:0009199 220 0.030
response to acid chemical GO:0001101 111 0.030
purine nucleotide catabolic process GO:0006195 211 0.030
positive regulation of gtp catabolic process GO:0033126 85 0.029
maintenance of location GO:0051235 89 0.029
cellular amino acid metabolic process GO:0006520 103 0.029
t cell differentiation GO:0030217 174 0.028
regulation of response to wounding GO:1903034 189 0.028
positive regulation of t cell activation GO:0050870 101 0.028
golgi vesicle transport GO:0048193 30 0.028
regulation of purine nucleotide catabolic process GO:0033121 122 0.028
organonitrogen compound catabolic process GO:1901565 264 0.028
macromolecule methylation GO:0043414 120 0.027
germ cell development GO:0007281 185 0.027
protein modification by small protein conjugation or removal GO:0070647 207 0.027
regulation of multi organism process GO:0043900 111 0.027
regulation of cytokine production GO:0001817 266 0.027
methylation GO:0032259 134 0.027
gland development GO:0048732 330 0.027
cation transmembrane transport GO:0098655 266 0.026
regulation of cell migration GO:0030334 219 0.026
nucleotide catabolic process GO:0009166 217 0.026
cell substrate adhesion GO:0031589 130 0.026
Mouse
regulation of b cell activation GO:0050864 81 0.026
lipid localization GO:0010876 126 0.026
nucleoside triphosphate catabolic process GO:0009143 205 0.025
neuron apoptotic process GO:0051402 142 0.025
cellularization GO:0007349 1 0.025
regulation of ras protein signal transduction GO:0046578 114 0.025
regulation of inflammatory response GO:0050727 147 0.025
proteasomal protein catabolic process GO:0010498 98 0.025
lung development GO:0030324 164 0.025
Mouse
inorganic cation transmembrane transport GO:0098662 207 0.024
glycoprotein catabolic process GO:0006516 5 0.024
leukocyte migration GO:0050900 124 0.024
regulation of nucleotide catabolic process GO:0030811 122 0.024
protein processing GO:0016485 163 0.024
nucleotide metabolic process GO:0009117 332 0.024
rac protein signal transduction GO:0016601 13 0.024
myeloid cell homeostasis GO:0002262 114 0.024
immune response activating signal transduction GO:0002757 116 0.024
activation of immune response GO:0002253 138 0.023
nucleoside triphosphate metabolic process GO:0009141 230 0.023
anion transport GO:0006820 177 0.023
positive regulation of nucleoside metabolic process GO:0045979 91 0.023
cellular response to lipid GO:0071396 145 0.023
regulation of protein complex assembly GO:0043254 83 0.023
cellular response to lipopolysaccharide GO:0071222 77 0.023
blood vessel morphogenesis GO:0048514 285 0.023
organelle localization GO:0051640 179 0.023
developmental maturation GO:0021700 193 0.023
sensory organ morphogenesis GO:0090596 242 0.023
regulation of map kinase activity GO:0043405 120 0.023
glycoprotein biosynthetic process GO:0009101 89 0.022
asymmetric stem cell division GO:0098722 3 0.022
cell adhesion GO:0007155 329 0.022
positive regulation of secretion by cell GO:1903532 114 0.022
tube closure GO:0060606 91 0.022
macromolecule glycosylation GO:0043413 55 0.022
actin cytoskeleton organization GO:0030036 220 0.022
negative regulation of cellular amine metabolic process GO:0033239 1 0.022
intracellular sterol transport GO:0032366 3 0.022
cellular response to dna damage stimulus GO:0006974 207 0.022
positive regulation of rab gtpase activity GO:0032851 7 0.022
nucleoside catabolic process GO:0009164 206 0.021
mammary gland epithelium development GO:0061180 65 0.021
protein localization to organelle GO:0033365 185 0.021
negative regulation of immune system process GO:0002683 209 0.021
regulation of lymphocyte differentiation GO:0045619 107 0.021
inorganic ion transmembrane transport GO:0098660 234 0.021
purine containing compound metabolic process GO:0072521 311 0.021
carbohydrate metabolic process GO:0005975 230 0.021
extracellular structure organization GO:0043062 148 0.021
single organism cell adhesion GO:0098602 156 0.021
organic hydroxy compound metabolic process GO:1901615 203 0.021
muscle tissue development GO:0060537 308 0.021
ribose phosphate metabolic process GO:0019693 291 0.020
regulation of cellular amino acid metabolic process GO:0006521 5 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
negative regulation of multi organism process GO:0043901 68 0.020
positive regulation of cell activation GO:0050867 158 0.020
regulation of protein catabolic process GO:0042176 108 0.020
regulation of t cell proliferation GO:0042129 92 0.020
regulation of cellular component size GO:0032535 121 0.020
myeloid cell differentiation GO:0030099 233 0.020
divalent inorganic cation homeostasis GO:0072507 138 0.020
transmission of nerve impulse GO:0019226 76 0.019
regulation of ras gtpase activity GO:0032318 88 0.019
cellular chemical homeostasis GO:0055082 215 0.019
alpha amino acid metabolic process GO:1901605 59 0.019
endocytosis GO:0006897 168 0.019
leukocyte chemotaxis GO:0030595 69 0.019
sodium ion transport GO:0006814 73 0.019
response to molecule of bacterial origin GO:0002237 143 0.019
positive regulation of toll like receptor 4 signaling pathway GO:0034145 1 0.019
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.018
epithelial tube formation GO:0072175 130 0.018
primary neural tube formation GO:0014020 95 0.018
negative regulation of molecular function GO:0044092 258 0.018
regulation of cellular ketone metabolic process GO:0010565 66 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
anatomical structure homeostasis GO:0060249 145 0.018
action potential GO:0001508 78 0.018
cellular metal ion homeostasis GO:0006875 151 0.018
nitrogen compound transport GO:0071705 271 0.018
neural tube closure GO:0001843 90 0.018
metencephalon development GO:0022037 89 0.018
response to peptide GO:1901652 136 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
cellular response to extracellular stimulus GO:0031668 81 0.017
sperm individualization GO:0007291 1 0.017
intracellular cholesterol transport GO:0032367 3 0.017
positive regulation of proteolysis GO:0045862 85 0.017
dna metabolic process GO:0006259 303 0.017
lateral inhibition GO:0046331 1 0.017
regulation of kinase activity GO:0043549 249 0.017
cation homeostasis GO:0055080 212 0.017
b cell activation GO:0042113 161 0.017
response to organonitrogen compound GO:0010243 246 0.017
extracellular matrix organization GO:0030198 147 0.017
heart morphogenesis GO:0003007 178 0.016
exocytosis GO:0006887 121 0.016
protein ubiquitination GO:0016567 171 0.016
wound healing GO:0042060 157 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
neural tube formation GO:0001841 108 0.016
viral process GO:0016032 41 0.016
response to oxidative stress GO:0006979 123 0.016
respiratory tube development GO:0030323 167 0.016
Mouse
regulation of t cell differentiation GO:0045580 83 0.016
peptide secretion GO:0002790 114 0.016
positive regulation of ras gtpase activity GO:0032320 65 0.016
protein secretion GO:0009306 111 0.016
negative regulation of growth GO:0045926 99 0.016
immune response regulating signaling pathway GO:0002764 125 0.016
cellular protein complex assembly GO:0043623 116 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
organic anion transport GO:0015711 137 0.016
regulation of leukocyte proliferation GO:0070663 121 0.016
tissue homeostasis GO:0001894 115 0.016
cell fate commitment GO:0045165 210 0.016
establishment of organelle localization GO:0051656 122 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
regulation of protein localization GO:0032880 231 0.016
epithelial cell proliferation GO:0050673 174 0.016
chemotaxis GO:0006935 247 0.016
respiratory system development GO:0060541 190 0.015
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.015
sequestering of calcium ion GO:0051208 18 0.015
retina development in camera type eye GO:0060041 119 0.015
negative regulation of transferase activity GO:0051348 85 0.015
protein maturation GO:0051604 176 0.015
tube formation GO:0035148 140 0.015
vacuole organization GO:0007033 38 0.015
cell activation involved in immune response GO:0002263 126 0.015
inflammatory response GO:0006954 244 0.015
positive regulation of lymphocyte proliferation GO:0050671 70 0.015
cellular lipid metabolic process GO:0044255 323 0.015
camera type eye development GO:0043010 266 0.015
central nervous system neuron differentiation GO:0021953 162 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.015
peptide transport GO:0015833 133 0.015
skeletal system development GO:0001501 356 0.015
sequestering of metal ion GO:0051238 19 0.015
negative regulation of lymphocyte activation GO:0051250 91 0.015
regulation of proteolysis GO:0030162 164 0.015
positive regulation of gtpase activity GO:0043547 85 0.015
fat cell differentiation GO:0045444 160 0.015
Mouse
divalent inorganic cation transport GO:0072511 178 0.015
lipoprotein metabolic process GO:0042157 43 0.015
cellular response to starvation GO:0009267 57 0.014
actin polymerization or depolymerization GO:0008154 54 0.014
eye photoreceptor cell differentiation GO:0001754 41 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
neural precursor cell proliferation GO:0061351 121 0.014
positive regulation of leukocyte proliferation GO:0070665 73 0.014
myeloid leukocyte migration GO:0097529 57 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
negative regulation of cell activation GO:0050866 111 0.014
myeloid leukocyte activation GO:0002274 83 0.014
retina morphogenesis in camera type eye GO:0060042 45 0.014
asymmetric neuroblast division GO:0055059 1 0.014
positive regulation of cell death GO:0010942 224 0.014
fertilization GO:0009566 127 0.014
interspecies interaction between organisms GO:0044419 83 0.014
actin filament polymerization GO:0030041 44 0.014
response to nutrient levels GO:0031667 109 0.014
cellular ion homeostasis GO:0006873 165 0.014
neural tube development GO:0021915 160 0.013
protein methylation GO:0006479 81 0.013
positive regulation of protein catabolic process GO:0045732 60 0.013
tumor necrosis factor ligand superfamily member 11 production GO:0072535 1 0.013
sensory perception GO:0007600 245 0.013
negative regulation of t cell activation GO:0050868 65 0.013
intracellular receptor signaling pathway GO:0030522 74 0.013
digestive system development GO:0055123 200 0.013
angiogenesis GO:0001525 201 0.013
muscle cell differentiation GO:0042692 261 0.013
regulation of actin cytoskeleton organization GO:0032956 84 0.013
labyrinthine layer development GO:0060711 49 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
regulation of gtp catabolic process GO:0033124 113 0.013
regulation of secretion GO:0051046 274 0.013
carboxylic acid transport GO:0046942 100 0.013
spermatid development GO:0007286 108 0.013
leukocyte homeostasis GO:0001776 79 0.013
actin filament organization GO:0007015 113 0.013
hydrogen ion transmembrane transport GO:1902600 25 0.013
oocyte axis specification GO:0007309 2 0.013
striated muscle tissue development GO:0014706 293 0.013
regulation of homeostatic process GO:0032844 182 0.013
rna 3 end processing GO:0031123 20 0.013
cell chemotaxis GO:0060326 81 0.013
neuron death GO:0070997 154 0.013
placenta development GO:0001890 140 0.013
positive regulation of cellular amine metabolic process GO:0033240 5 0.012
intracellular protein transport GO:0006886 204 0.012
regulation of transmembrane transport GO:0034762 128 0.012
axonogenesis GO:0007409 274 0.012
photoreceptor cell differentiation GO:0046530 52 0.012
positive regulation of transferase activity GO:0051347 167 0.012
negative regulation of response to wounding GO:1903035 77 0.012
mrna 3 end processing GO:0031124 16 0.012
regulation of protein secretion GO:0050708 82 0.012
positive regulation of protein secretion GO:0050714 52 0.012
membrane organization GO:0061024 245 0.012
apoptotic signaling pathway GO:0097190 306 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
regulation of cellular amine metabolic process GO:0033238 20 0.012
neuronal action potential GO:0019228 54 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
endomembrane system organization GO:0010256 147 0.012
oocyte construction GO:0007308 2 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
positive regulation of podosome assembly GO:0071803 3 0.012
regulation of cellular response to stress GO:0080135 159 0.012
tissue remodeling GO:0048771 102 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
cell maturation GO:0048469 127 0.012
regulation of neuron death GO:1901214 134 0.012
regulation of neuron projection development GO:0010975 169 0.012
response to light stimulus GO:0009416 135 0.012
microtubule based process GO:0007017 236 0.012
divalent metal ion transport GO:0070838 172 0.012
lytic vacuole organization GO:0080171 21 0.011
calcium ion homeostasis GO:0055074 127 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.011
regulation of neuron differentiation GO:0045664 281 0.011
positive regulation of innate immune response GO:0045089 80 0.011
mrna metabolic process GO:0016071 84 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
regulation of innate immune response GO:0045088 91 0.011
peptidyl amino acid modification GO:0018193 336 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
positive regulation of secretion GO:0051047 130 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.011
muscle system process GO:0003012 141 0.011
multicellular organismal signaling GO:0035637 91 0.011
locomotory behavior GO:0007626 195 0.011
immune effector process GO:0002252 321 0.011
localization within membrane GO:0051668 4 0.011
negative regulation of t cell proliferation GO:0042130 38 0.011
activation of mapk activity GO:0000187 59 0.011
er associated ubiquitin dependent protein catabolic process GO:0030433 10 0.011
granulocyte migration GO:0097530 43 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.011
intermediate filament cytoskeleton organization GO:0045104 26 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
regulation of protein transport GO:0051223 163 0.011
rho protein signal transduction GO:0007266 32 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
positive regulation of phagocytosis engulfment GO:0060100 3 0.010
regulation of neuron apoptotic process GO:0043523 122 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
stem cell proliferation GO:0072089 117 0.010
regulation of protein kinase activity GO:0045859 232 0.010
regulation of metal ion transport GO:0010959 106 0.010
regulation of chromatin silencing GO:0031935 2 0.010
regulation of membrane potential GO:0042391 192 0.010
cellular response to acid chemical GO:0071229 68 0.010
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.010
lymphocyte activation involved in immune response GO:0002285 93 0.010
outflow tract morphogenesis GO:0003151 53 0.010
regulation of mrna metabolic process GO:1903311 43 0.010
calcium ion transport into cytosol GO:0060402 48 0.010
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010
negative regulation of synapse assembly GO:0051964 3 0.010
positive regulation of ossification GO:0045778 47 0.010
nucleoside monophosphate catabolic process GO:0009125 59 0.010
negative regulation of neuron death GO:1901215 98 0.010
intermediate filament based process GO:0045103 27 0.010

Fndc3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.018
disease of anatomical entity DOID:7 0 0.018
musculoskeletal system disease DOID:17 0 0.018
connective tissue disease DOID:65 0 0.018
nervous system disease DOID:863 0 0.018
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015
retinal disease DOID:5679 0 0.013
retinal degeneration DOID:8466 0 0.013
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013