Mus musculus

61 known processes

Sirpa

signal-regulatory protein alpha

(Aliases: CD172a,Ptpns1,P84,SIRP,AI835480,SHP-1,Bit,SHPS-1)

Sirpa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
coagulation GO:0050817 78 0.790
amine metabolic process GO:0009308 45 0.703
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.686
wound healing GO:0042060 157 0.628
cell adhesion GO:0007155 329 0.599
regulation of transferase activity GO:0051338 263 0.582
leukocyte chemotaxis GO:0030595 69 0.578
axonogenesis GO:0007409 274 0.554
small gtpase mediated signal transduction GO:0007264 97 0.472
cellular amino acid metabolic process GO:0006520 103 0.470
chemotaxis GO:0006935 247 0.470
hemostasis GO:0007599 78 0.469
regulation of protein kinase activity GO:0045859 232 0.444
single organismal cell cell adhesion GO:0016337 131 0.442
Human
single organism cell adhesion GO:0098602 156 0.439
Human
platelet activation GO:0030168 40 0.435
regulation of cellular amine metabolic process GO:0033238 20 0.434
myeloid cell differentiation GO:0030099 233 0.421
axon guidance GO:0007411 141 0.403
organonitrogen compound catabolic process GO:1901565 264 0.395
peptidyl amino acid modification GO:0018193 336 0.388
positive regulation of gtp catabolic process GO:0033126 85 0.385
leukocyte migration GO:0050900 124 0.381
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.363
response to peptide hormone GO:0043434 127 0.358
inflammatory response GO:0006954 244 0.351
mapk cascade GO:0000165 281 0.340
cellular ion homeostasis GO:0006873 165 0.336
peptidyl tyrosine phosphorylation GO:0018108 143 0.328
blood coagulation GO:0007596 76 0.326
ion transmembrane transport GO:0034220 361 0.326
cell chemotaxis GO:0060326 81 0.322
regulation of map kinase activity GO:0043405 120 0.317
phagocytosis GO:0006909 66 0.312
nucleoside catabolic process GO:0009164 206 0.311
response to peptide GO:1901652 136 0.305
positive regulation of transferase activity GO:0051347 167 0.303
positive regulation of response to wounding GO:1903036 66 0.302
regulation of kinase activity GO:0043549 249 0.297
neuron projection guidance GO:0097485 141 0.292
cellular amine metabolic process GO:0044106 44 0.288
cellular ketone metabolic process GO:0042180 84 0.285
cellular lipid metabolic process GO:0044255 323 0.278
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.269
regulation of cell migration GO:0030334 219 0.267
cerebellar granule cell precursor tangential migration GO:0021935 1 0.263
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.261
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.256
regulation of lymphocyte activation GO:0051249 240 0.251
Human
regulation of cell motility GO:2000145 236 0.250
purine nucleoside triphosphate metabolic process GO:0009144 226 0.246
negative regulation of protein phosphorylation GO:0001933 126 0.244
homotypic cell cell adhesion GO:0034109 28 0.243
positive regulation of kinase activity GO:0033674 155 0.237
carbohydrate derivative catabolic process GO:1901136 231 0.235
ribonucleoside triphosphate catabolic process GO:0009203 199 0.233
regulation of neuron projection development GO:0010975 169 0.233
purine nucleotide metabolic process GO:0006163 302 0.231
positive regulation of chemotaxis GO:0050921 38 0.231
circulatory system process GO:0003013 197 0.228
cell substrate adhesion GO:0031589 130 0.228
cellular response to peptide GO:1901653 92 0.225
guanosine containing compound catabolic process GO:1901069 144 0.225
cognition GO:0050890 149 0.221
positive regulation of protein phosphorylation GO:0001934 242 0.219
gland development GO:0048732 330 0.217
sensory organ morphogenesis GO:0090596 242 0.214
regulation of vesicle mediated transport GO:0060627 139 0.209
blood vessel morphogenesis GO:0048514 285 0.208
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.208
epidermis development GO:0008544 187 0.207
glycoprotein biosynthetic process GO:0009101 89 0.205
myeloid leukocyte migration GO:0097529 57 0.204
positive regulation of cell migration GO:0030335 109 0.204
regulation of cellular amino acid metabolic process GO:0006521 5 0.204
positive regulation of rho gtpase activity GO:0032321 41 0.204
myeloid leukocyte mediated immunity GO:0002444 42 0.203
positive regulation of gtpase activity GO:0043547 85 0.201
positive regulation of nucleotide catabolic process GO:0030813 88 0.198
regulation of cellular ketone metabolic process GO:0010565 66 0.189
developmental maturation GO:0021700 193 0.188
sphingolipid metabolic process GO:0006665 45 0.186
negative regulation of map kinase activity GO:0043407 34 0.185
gtp catabolic process GO:0006184 143 0.185
connective tissue development GO:0061448 179 0.184
regionalization GO:0003002 337 0.184
developmental growth involved in morphogenesis GO:0060560 138 0.184
regulation of gtp catabolic process GO:0033124 113 0.183
glycosyl compound catabolic process GO:1901658 206 0.182
purine nucleotide catabolic process GO:0006195 211 0.182
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.181
regulation of cell activation GO:0050865 289 0.180
Human
response to lipopolysaccharide GO:0032496 128 0.177
ribonucleoside catabolic process GO:0042454 206 0.177
cellular chemical homeostasis GO:0055082 215 0.176
regulation of protein serine threonine kinase activity GO:0071900 157 0.173
regulation of body fluid levels GO:0050878 162 0.172
positive regulation of mapk cascade GO:0043410 170 0.171
calcium ion transmembrane transport GO:0070588 85 0.171
fatty acid metabolic process GO:0006631 121 0.167
regulation of ras gtpase activity GO:0032318 88 0.167
g protein coupled receptor signaling pathway GO:0007186 243 0.161
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.161
ribonucleotide metabolic process GO:0009259 291 0.160
regulation of system process GO:0044057 200 0.158
regulation of response to wounding GO:1903034 189 0.158
ribonucleoside metabolic process GO:0009119 245 0.151
neuron apoptotic process GO:0051402 142 0.148
guanosine containing compound metabolic process GO:1901068 144 0.147
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.147
aromatic compound catabolic process GO:0019439 286 0.146
myeloid leukocyte activation GO:0002274 83 0.146
purine ribonucleotide metabolic process GO:0009150 290 0.146
lamellipodium organization GO:0097581 29 0.144
lipid catabolic process GO:0016042 69 0.143
positive regulation of cellular catabolic process GO:0031331 148 0.143
regulation of purine nucleotide catabolic process GO:0033121 122 0.143
nucleoside metabolic process GO:0009116 246 0.143
carbohydrate metabolic process GO:0005975 230 0.142
ras protein signal transduction GO:0007265 77 0.141
purine nucleoside metabolic process GO:0042278 241 0.141
semaphorin plexin signaling pathway involved in bone trabecula morphogenesis GO:1900220 2 0.139
nucleotide catabolic process GO:0009166 217 0.139
purine ribonucleotide catabolic process GO:0009154 208 0.138
regulation of myeloid cell differentiation GO:0045637 96 0.137
rho protein signal transduction GO:0007266 32 0.135
nucleobase containing small molecule metabolic process GO:0055086 352 0.134
calcium ion homeostasis GO:0055074 127 0.134
leukocyte activation involved in immune response GO:0002366 126 0.134
cellular response to peptide hormone stimulus GO:0071375 92 0.132
neural tube development GO:0021915 160 0.132
cellular response to organonitrogen compound GO:0071417 145 0.131
positive regulation of ras gtpase activity GO:0032320 65 0.130
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.130
hematopoietic progenitor cell differentiation GO:0002244 143 0.127
positive regulation of protein kinase activity GO:0045860 144 0.127
cellular metal ion homeostasis GO:0006875 151 0.126
exocytosis GO:0006887 121 0.125
glial cell differentiation GO:0010001 131 0.125
positive regulation of neuron projection development GO:0010976 79 0.124
regulation of nucleotide metabolic process GO:0006140 169 0.124
cellular response to lipopolysaccharide GO:0071222 77 0.123
homeostasis of number of cells GO:0048872 210 0.123
skeletal system development GO:0001501 356 0.123
myeloid cell activation involved in immune response GO:0002275 34 0.123
glycerophospholipid metabolic process GO:0006650 71 0.123
negative regulation of intracellular signal transduction GO:1902532 167 0.122
regulation of mapk cascade GO:0043408 248 0.122
ribonucleotide catabolic process GO:0009261 208 0.120
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.118
activation of immune response GO:0002253 138 0.117
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.117
angiogenesis GO:0001525 201 0.116
cell cell junction organization GO:0045216 72 0.114
positive regulation of cell development GO:0010720 237 0.113
gtp metabolic process GO:0046039 144 0.112
regulation of actin cytoskeleton organization GO:0032956 84 0.112
tissue remodeling GO:0048771 102 0.112
glycosyl compound metabolic process GO:1901657 246 0.111
divalent inorganic cation transport GO:0072511 178 0.111
synapse organization GO:0050808 125 0.110
synapse assembly GO:0007416 56 0.109
regulation of purine nucleotide metabolic process GO:1900542 169 0.108
regulation of ras protein signal transduction GO:0046578 114 0.108
positive regulation of cell activation GO:0050867 158 0.107
Human
learning or memory GO:0007611 148 0.106
positive regulation of protein modification process GO:0031401 299 0.105
cation transport GO:0006812 399 0.105
regulation of rho gtpase activity GO:0032319 58 0.104
macrophage differentiation GO:0030225 20 0.103
regulation of chemotaxis GO:0050920 53 0.103
transmembrane transport GO:0055085 412 0.102
positive regulation of organelle organization GO:0010638 128 0.102
regulation of cytokine production GO:0001817 266 0.102
regulation of protein localization GO:0032880 231 0.101
purine ribonucleoside catabolic process GO:0046130 205 0.100
nucleoside phosphate catabolic process GO:1901292 222 0.100
granulocyte migration GO:0097530 43 0.098
activation of mapk activity involved in innate immune response GO:0035419 2 0.098
response to insulin GO:0032868 100 0.098
regulation of myeloid leukocyte differentiation GO:0002761 58 0.097
regulation of cellular component size GO:0032535 121 0.097
leukocyte differentiation GO:0002521 342 0.097
camera type eye development GO:0043010 266 0.097
sensory perception GO:0007600 245 0.097
positive regulation of nucleoside metabolic process GO:0045979 91 0.097
calcium ion transport GO:0006816 159 0.096
positive regulation of cellular amine metabolic process GO:0033240 5 0.096
response to light stimulus GO:0009416 135 0.095
primary neural tube formation GO:0014020 95 0.094
immune response regulating signaling pathway GO:0002764 125 0.094
purine ribonucleoside metabolic process GO:0046128 241 0.094
multicellular organismal homeostasis GO:0048871 164 0.092
smooth muscle cell migration GO:0014909 10 0.091
phospholipid metabolic process GO:0006644 87 0.091
embryonic organ morphogenesis GO:0048562 276 0.091
detection of light stimulus GO:0009583 25 0.091
wnt signaling pathway GO:0016055 188 0.090
regulation of neuron differentiation GO:0045664 281 0.089
maintenance of location GO:0051235 89 0.088
protein autophosphorylation GO:0046777 61 0.088
negative regulation of protein metabolic process GO:0051248 282 0.088
purine containing compound catabolic process GO:0072523 213 0.087
leukocyte mediated immunity GO:0002443 174 0.086
organelle assembly GO:0070925 177 0.086
positive regulation of protein kinase b signaling GO:0051897 32 0.085
regulation of vasculature development GO:1901342 88 0.085
glycerolipid metabolic process GO:0046486 122 0.084
response to radiation GO:0009314 165 0.083
negative regulation of cell proliferation GO:0008285 296 0.083
microglia differentiation GO:0014004 2 0.082
bone development GO:0060348 120 0.082
regulation of inflammatory response GO:0050727 147 0.082
positive regulation of cell projection organization GO:0031346 95 0.081
detection of external stimulus GO:0009581 61 0.081
oxidation reduction process GO:0055114 342 0.081
nucleotide metabolic process GO:0009117 332 0.081
actin polymerization or depolymerization GO:0008154 54 0.081
peptidyl serine phosphorylation GO:0018105 74 0.080
positive regulation of rac gtpase activity GO:0032855 14 0.080
granulocyte chemotaxis GO:0071621 39 0.080
phosphatidylinositol metabolic process GO:0046488 45 0.080
skin development GO:0043588 220 0.080
regulation of cell projection organization GO:0031344 206 0.080
nucleoside phosphate metabolic process GO:0006753 338 0.079
endocytosis GO:0006897 168 0.079
response to organonitrogen compound GO:0010243 246 0.079
forebrain development GO:0030900 302 0.079
ribonucleoside triphosphate metabolic process GO:0009199 220 0.077
positive regulation of endocytosis GO:0045807 42 0.076
monosaccharide transport GO:0015749 58 0.076
lipid localization GO:0010876 126 0.075
detection of abiotic stimulus GO:0009582 60 0.074
nucleoside triphosphate metabolic process GO:0009141 230 0.073
regulated secretory pathway GO:0045055 32 0.073
monocarboxylic acid metabolic process GO:0032787 191 0.073
regulation of transmembrane transport GO:0034762 128 0.072
regulation of actin filament length GO:0030832 45 0.072
regulation of intracellular transport GO:0032386 159 0.072
renal system development GO:0072001 225 0.072
regulation of cell substrate adhesion GO:0010810 73 0.071
response to growth factor GO:0070848 198 0.071
germ cell development GO:0007281 185 0.071
multicellular organismal signaling GO:0035637 91 0.071
cytokine mediated signaling pathway GO:0019221 115 0.071
cytoplasmic transport GO:0016482 234 0.070
inorganic cation transmembrane transport GO:0098662 207 0.069
kidney development GO:0001822 213 0.069
anatomical structure arrangement GO:0048532 20 0.069
antigen receptor mediated signaling pathway GO:0050851 64 0.068
leukocyte homeostasis GO:0001776 79 0.068
regulation of hormone levels GO:0010817 211 0.068
interleukin 5 secretion GO:0072603 2 0.067
positive regulation of cell motility GO:2000147 116 0.067
positive regulation of neuron differentiation GO:0045666 141 0.067
cellular homeostasis GO:0019725 240 0.067
negative regulation of transferase activity GO:0051348 85 0.067
positive regulation of lipid metabolic process GO:0045834 40 0.067
negative regulation of mapk cascade GO:0043409 65 0.066
metal ion homeostasis GO:0055065 189 0.066
regulation of cell cycle GO:0051726 281 0.066
branchiomotor neuron axon guidance GO:0021785 7 0.066
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.066
platelet aggregation GO:0070527 20 0.066
sequestering of metal ion GO:0051238 19 0.065
sensory perception of chemical stimulus GO:0007606 51 0.065
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.065
protein localization to organelle GO:0033365 185 0.065
leukocyte degranulation GO:0043299 27 0.064
positive regulation of growth GO:0045927 104 0.061
muscle cell differentiation GO:0042692 261 0.061
organophosphate catabolic process GO:0046434 232 0.060
regulation of actin filament based process GO:0032970 99 0.060
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.060
glycoprotein metabolic process GO:0009100 116 0.060
cell growth GO:0016049 130 0.060
glucose transport GO:0015758 56 0.059
peptidyl tyrosine modification GO:0018212 145 0.059
macromolecule glycosylation GO:0043413 55 0.059
innate immune response GO:0045087 157 0.059
toll like receptor 9 signaling pathway GO:0034162 6 0.059
neural tube formation GO:0001841 108 0.059
blood circulation GO:0008015 195 0.058
regulation of cellular component biogenesis GO:0044087 181 0.058
nuclear division GO:0000280 158 0.058
synaptic transmission GO:0007268 329 0.058
divalent metal ion transport GO:0070838 172 0.057
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.057
branching morphogenesis of an epithelial tube GO:0048754 159 0.057
locomotory behavior GO:0007626 195 0.057
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.057
membrane lipid metabolic process GO:0006643 53 0.056
regulation of mast cell activation GO:0033003 21 0.056
metencephalon development GO:0022037 89 0.056
positive regulation of ion transport GO:0043270 65 0.056
positive regulation of inflammatory response GO:0050729 47 0.056
detection of stimulus GO:0051606 84 0.056
negative regulation of protein modification process GO:0031400 163 0.056
male gamete generation GO:0048232 285 0.056
canonical wnt signaling pathway GO:0060070 130 0.056
development of primary sexual characteristics GO:0045137 143 0.056
photoreceptor cell development GO:0042461 40 0.056
positive regulation of behavior GO:0048520 40 0.055
mast cell activation GO:0045576 27 0.055
t cell activation GO:0042110 289 0.055
Human
multicellular organism growth GO:0035264 161 0.055
positive regulation of apoptotic process GO:0043065 217 0.055
organic hydroxy compound metabolic process GO:1901615 203 0.055
negative regulation of cellular component organization GO:0051129 194 0.055
epidermal growth factor receptor signaling pathway via i kappab kinase nf kappab cascade GO:0038168 1 0.054
neuron projection extension GO:1990138 64 0.054
activation of mapk activity GO:0000187 59 0.054
negative regulation of cellular protein metabolic process GO:0032269 247 0.054
rhythmic process GO:0048511 174 0.053
glycosylation GO:0070085 62 0.053
positive regulation of hydrolase activity GO:0051345 148 0.053
neutrophil migration GO:1990266 37 0.053
insulin receptor signaling pathway GO:0008286 49 0.053
heterocycle catabolic process GO:0046700 280 0.053
ceramide metabolic process GO:0006672 31 0.053
regulation of neuron apoptotic process GO:0043523 122 0.053
positive regulation of leukocyte differentiation GO:1902107 86 0.053
substrate adhesion dependent cell spreading GO:0034446 30 0.052
intracellular protein transport GO:0006886 204 0.052
neuronal action potential GO:0019228 54 0.052
organic acid transport GO:0015849 101 0.052
retina development in camera type eye GO:0060041 119 0.052
dendrite development GO:0016358 115 0.052
regulation of leukocyte proliferation GO:0070663 121 0.052
regulation of membrane potential GO:0042391 192 0.051
protein polymerization GO:0051258 57 0.051
positive regulation of myeloid cell differentiation GO:0045639 43 0.051
regulation of platelet activation GO:0010543 17 0.051
positive regulation of lymphocyte activation GO:0051251 140 0.051
Human
sympathetic neuron projection guidance GO:0097491 4 0.051
positive regulation of nervous system development GO:0051962 221 0.051
purine nucleoside triphosphate catabolic process GO:0009146 203 0.051
regulation of leukocyte mediated immunity GO:0002703 104 0.051
regulation of extent of cell growth GO:0061387 52 0.051
cytokine secretion GO:0050663 72 0.051
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.050
eye photoreceptor cell development GO:0042462 31 0.050
stress activated protein kinase signaling cascade GO:0031098 81 0.050
action potential GO:0001508 78 0.050
regulation of organelle organization GO:0033043 289 0.050
cellular response to insulin stimulus GO:0032869 78 0.050
regulation of cellular catabolic process GO:0031329 242 0.050
actin filament bundle assembly GO:0051017 40 0.050
lysosome organization GO:0007040 21 0.050
regulation of ion transmembrane transport GO:0034765 119 0.049
vacuole organization GO:0007033 38 0.049
ribose phosphate metabolic process GO:0019693 291 0.049
immune response activating signal transduction GO:0002757 116 0.049
inner ear receptor cell development GO:0060119 39 0.049
trunk neural crest cell migration GO:0036484 4 0.049
peptidyl threonine phosphorylation GO:0018107 31 0.049
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.049
cell division GO:0051301 120 0.049
purine containing compound metabolic process GO:0072521 311 0.048
inorganic ion transmembrane transport GO:0098660 234 0.048
neutrophil chemotaxis GO:0030593 36 0.048
actin cytoskeleton organization GO:0030036 220 0.048
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.048
positive regulation of macrophage derived foam cell differentiation GO:0010744 4 0.048
dna metabolic process GO:0006259 303 0.048
regulation of cell adhesion GO:0030155 154 0.048
Human
cellular response to hormone stimulus GO:0032870 150 0.048
cell activation involved in immune response GO:0002263 126 0.048
cell junction organization GO:0034330 77 0.048
carbohydrate derivative biosynthetic process GO:1901137 183 0.047
positive regulation of nucleotide metabolic process GO:0045981 114 0.047
digestive tract morphogenesis GO:0048546 147 0.047
regulation of axon extension GO:0030516 43 0.047
cellular carbohydrate metabolic process GO:0044262 119 0.047
epithelial tube morphogenesis GO:0060562 303 0.047
tube closure GO:0060606 91 0.047
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 9 0.047
response to alcohol GO:0097305 48 0.047
positive regulation of t cell activation GO:0050870 101 0.046
Human
actin filament organization GO:0007015 113 0.046
myelination in peripheral nervous system GO:0022011 19 0.046
positive regulation of phagocytosis GO:0050766 26 0.046
erythrocyte differentiation GO:0030218 88 0.046
positive regulation of smooth muscle cell migration GO:0014911 4 0.046
regulation of blood coagulation GO:0030193 28 0.046
mucopolysaccharide metabolic process GO:1903510 25 0.045
pma inducible membrane protein ectodomain proteolysis GO:0051088 1 0.045
regulation of heart contraction GO:0008016 77 0.045
reactive oxygen species biosynthetic process GO:1903409 8 0.045
regulation of secretion by cell GO:1903530 249 0.045
positive regulation of thymocyte migration GO:2000412 2 0.045
tissue homeostasis GO:0001894 115 0.045
response to oxidative stress GO:0006979 123 0.045
protein glycosylation GO:0006486 55 0.045
sympathetic neuron projection extension GO:0097490 4 0.045
regulation of defense response GO:0031347 233 0.044
muscle cell migration GO:0014812 19 0.044
cation homeostasis GO:0055080 212 0.044
lipid biosynthetic process GO:0008610 179 0.044
extracellular matrix dependent thymocyte migration GO:0072680 1 0.044
g protein coupled purinergic nucleotide receptor signaling pathway GO:0035589 1 0.044
myelination GO:0042552 74 0.044
membrane organization GO:0061024 245 0.044
central nervous system neuron differentiation GO:0021953 162 0.044
negative regulation of kinase activity GO:0033673 81 0.044
embryonic limb morphogenesis GO:0030326 126 0.044
positive regulation of defense response GO:0031349 124 0.044
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.043
extrinsic apoptotic signaling pathway GO:0097191 126 0.043
regulation of actin filament polymerization GO:0030833 38 0.043
heart process GO:0003015 94 0.043
negative regulation of growth GO:0045926 99 0.042
positive regulation of map kinase activity GO:0043406 84 0.042
cellular response to molecule of bacterial origin GO:0071219 83 0.042
response to organic cyclic compound GO:0014070 198 0.042
stem cell proliferation GO:0072089 117 0.042
fatty acid transmembrane transport GO:1902001 1 0.042
regulation of axon guidance GO:1902667 13 0.041
regulation of muscle contraction GO:0006937 49 0.041
retina morphogenesis in camera type eye GO:0060042 45 0.041
hair cycle GO:0042633 90 0.041
regulation of receptor activity GO:0010469 41 0.041
placenta development GO:0001890 140 0.041
regulation of ral gtpase activity GO:0032315 4 0.041
regulation of nucleoside metabolic process GO:0009118 130 0.040
motor neuron axon guidance GO:0008045 26 0.040
regulation of smooth muscle cell migration GO:0014910 6 0.040
regulation of coagulation GO:0050818 31 0.040
spermatid differentiation GO:0048515 115 0.040
embryonic epithelial tube formation GO:0001838 130 0.040
regulation of phagocytosis GO:0050764 33 0.040
sequestering of calcium ion GO:0051208 18 0.040
semaphorin plexin signaling pathway involved in axon guidance GO:1902287 6 0.040
regulation of anatomical structure size GO:0090066 178 0.040
post embryonic retina morphogenesis in camera type eye GO:0060060 3 0.039
insulin secretion GO:0030073 89 0.039
lymphocyte proliferation GO:0046651 164 0.039
positive regulation of cell adhesion GO:0045785 80 0.039
Human
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.039
cytokine production GO:0001816 319 0.039
dephosphorylation GO:0016311 129 0.039
skeletal system morphogenesis GO:0048705 203 0.038
lytic vacuole organization GO:0080171 21 0.038
mitotic cell cycle GO:0000278 195 0.038
memory GO:0007613 58 0.038
epithelial tube formation GO:0072175 130 0.038
inner ear morphogenesis GO:0042472 101 0.038
negative regulation of phosphate metabolic process GO:0045936 184 0.038
actin filament polymerization GO:0030041 44 0.038
development of primary female sexual characteristics GO:0046545 73 0.038
b cell activation GO:0042113 161 0.037
regulation of cytoskeleton organization GO:0051493 122 0.037
positive regulation of cell growth GO:0030307 33 0.037
regulation of osteoclast differentiation GO:0045670 36 0.037
positive regulation of fibronectin dependent thymocyte migration GO:2000415 1 0.037
positive regulation of cytokine production GO:0001819 174 0.037
regulation of hydrolase activity GO:0051336 246 0.037
cellular nitrogen compound catabolic process GO:0044270 280 0.037
anatomical structure homeostasis GO:0060249 145 0.037
alcohol metabolic process GO:0006066 116 0.036
reactive nitrogen species metabolic process GO:2001057 0 0.036
neural tube closure GO:0001843 90 0.036
fibroblast migration GO:0010761 21 0.036
protein kinase b signaling GO:0043491 74 0.036
protein catabolic process GO:0030163 221 0.036
female sex differentiation GO:0046660 84 0.036
divalent inorganic cation homeostasis GO:0072507 138 0.036
negative regulation of nervous system development GO:0051961 156 0.036
lysosome localization GO:0032418 20 0.036
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.036
posttranscriptional regulation of gene expression GO:0010608 155 0.036
small molecule catabolic process GO:0044282 71 0.035
regulation of calcium ion transport GO:0051924 69 0.035
negative regulation of neuron death GO:1901215 98 0.035
adaptive immune response GO:0002250 155 0.035
epithelial cell proliferation GO:0050673 174 0.035
regulation of protein catabolic process GO:0042176 108 0.035
photoreceptor cell morphogenesis GO:0008594 3 0.035
organelle localization GO:0051640 179 0.035
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.034
innate immune response activating signal transduction GO:0002758 50 0.034
transmission of nerve impulse GO:0019226 76 0.034
bone remodeling GO:0046849 53 0.034
negative regulation of immune system process GO:0002683 209 0.034
regulation of protein transport GO:0051223 163 0.034
regulation of peptidyl serine phosphorylation GO:0033135 39 0.034
regulation of protein complex disassembly GO:0043244 28 0.034
thymocyte migration GO:0072679 2 0.034
regulation of cell growth GO:0001558 91 0.034
hypothalamus gonadotrophin releasing hormone neuron development GO:0021888 4 0.034
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.034
morphogenesis of embryonic epithelium GO:0016331 159 0.034

Sirpa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.112
musculoskeletal system disease DOID:17 0 0.112
connective tissue disease DOID:65 0 0.112
nervous system disease DOID:863 0 0.071
central nervous system disease DOID:331 0 0.053
cerebral degeneration DOID:1443 0 0.051
brain disease DOID:936 0 0.051