Mus musculus

0 known processes

Tcl1b3

T-cell leukemia/lymphoma 1B, 3

Tcl1b3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
immune effector process GO:0002252 321 0.111
regulation of membrane potential GO:0042391 192 0.107
amine metabolic process GO:0009308 45 0.101
purine nucleotide metabolic process GO:0006163 302 0.100
nucleotide metabolic process GO:0009117 332 0.084
regulation of cell activation GO:0050865 289 0.080
purine containing compound metabolic process GO:0072521 311 0.076
purine ribonucleotide metabolic process GO:0009150 290 0.073
negative regulation of protein metabolic process GO:0051248 282 0.067
nucleoside phosphate metabolic process GO:0006753 338 0.067
inflammatory response GO:0006954 244 0.065
positive regulation of cell activation GO:0050867 158 0.065
lymphocyte differentiation GO:0030098 242 0.065
leukocyte mediated immunity GO:0002443 174 0.064
cellular amine metabolic process GO:0044106 44 0.063
multicellular organismal signaling GO:0035637 91 0.060
response to organonitrogen compound GO:0010243 246 0.055
circulatory system process GO:0003013 197 0.054
nucleobase containing small molecule metabolic process GO:0055086 352 0.052
aromatic compound catabolic process GO:0019439 286 0.051
cellular amino acid metabolic process GO:0006520 103 0.050
organonitrogen compound biosynthetic process GO:1901566 192 0.050
regulation of leukocyte differentiation GO:1902105 159 0.050
regulation of cellular amino acid metabolic process GO:0006521 5 0.049
regulation of cellular amine metabolic process GO:0033238 20 0.048
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.048
heterocycle catabolic process GO:0046700 280 0.048
regulation of defense response GO:0031347 233 0.046
regulation of inflammatory response GO:0050727 147 0.046
macromolecule catabolic process GO:0009057 281 0.046
ensheathment of neurons GO:0007272 76 0.046
blood circulation GO:0008015 195 0.045
ribose phosphate metabolic process GO:0019693 291 0.044
ribonucleotide metabolic process GO:0009259 291 0.043
carbohydrate derivative biosynthetic process GO:1901137 183 0.043
glycosyl compound metabolic process GO:1901657 246 0.043
positive regulation of monocyte chemotaxis GO:0090026 2 0.042
cytokine production GO:0001816 319 0.041
regulation of nucleotide metabolic process GO:0006140 169 0.041
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.041
t cell activation GO:0042110 289 0.041
defense response to other organism GO:0098542 197 0.041
response to peptide GO:1901652 136 0.041
blood vessel morphogenesis GO:0048514 285 0.039
cellular response to lipid GO:0071396 145 0.039
small gtpase mediated signal transduction GO:0007264 97 0.038
small molecule biosynthetic process GO:0044283 132 0.036
cell activation involved in immune response GO:0002263 126 0.036
adaptive immune response GO:0002250 155 0.036
organic cyclic compound catabolic process GO:1901361 295 0.036
negative regulation of cellular protein metabolic process GO:0032269 247 0.035
leukocyte differentiation GO:0002521 342 0.035
leukocyte activation involved in immune response GO:0002366 126 0.035
nucleoside phosphate biosynthetic process GO:1901293 79 0.034
organophosphate catabolic process GO:0046434 232 0.034
carbohydrate derivative catabolic process GO:1901136 231 0.034
lymphocyte activation involved in immune response GO:0002285 93 0.033
regulation of purine nucleotide metabolic process GO:1900542 169 0.033
transmission of nerve impulse GO:0019226 76 0.033
negative regulation of phosphorus metabolic process GO:0010563 184 0.033
negative regulation of multi organism process GO:0043901 68 0.033
peptidyl amino acid modification GO:0018193 336 0.032
regulation of hydrolase activity GO:0051336 246 0.032
positive regulation of protein modification process GO:0031401 299 0.032
sensory perception GO:0007600 245 0.031
regulation of protein localization GO:0032880 231 0.031
male gamete generation GO:0048232 285 0.031
negative regulation of immune system process GO:0002683 209 0.030
spermatogenesis GO:0007283 284 0.030
ras protein signal transduction GO:0007265 77 0.030
regulation of skeletal muscle fiber development GO:0048742 36 0.030
negative regulation of molecular function GO:0044092 258 0.030
response to peptide hormone GO:0043434 127 0.030
interleukin 8 production GO:0032637 4 0.030
heart process GO:0003015 94 0.030
activation of immune response GO:0002253 138 0.030
protein maturation GO:0051604 176 0.029
cell type specific apoptotic process GO:0097285 268 0.029
response to lipopolysaccharide GO:0032496 128 0.029
positive regulation of lymphocyte activation GO:0051251 140 0.028
regulation of t cell activation GO:0050863 170 0.028
eosinophil migration GO:0072677 3 0.028
negative regulation of inflammatory response GO:0050728 61 0.028
positive regulation of defense response GO:0031349 124 0.028
neuron death GO:0070997 154 0.028
leukocyte migration GO:0050900 124 0.027
regulation of cellular ketone metabolic process GO:0010565 66 0.027
t helper 2 cell cytokine production GO:0035745 4 0.026
t cell differentiation GO:0030217 174 0.026
protein catabolic process GO:0030163 221 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
mapk cascade GO:0000165 281 0.026
purine nucleotide biosynthetic process GO:0006164 65 0.026
regulation of cytokine production GO:0001817 266 0.026
cellular ketone metabolic process GO:0042180 84 0.026
g protein coupled receptor signaling pathway GO:0007186 243 0.026
regulation of lymphocyte activation GO:0051249 240 0.026
defense response to virus GO:0051607 68 0.025
response to bacterial lipoprotein GO:0032493 4 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
regulation of response to wounding GO:1903034 189 0.025
sulfur compound metabolic process GO:0006790 100 0.024
striated muscle tissue development GO:0014706 293 0.024
gliogenesis GO:0042063 141 0.024
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.024
heart contraction GO:0060047 93 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
negative regulation of cytokine production GO:0001818 84 0.024
oxidation reduction process GO:0055114 342 0.023
cyclic purine nucleotide metabolic process GO:0052652 43 0.023
positive regulation of thymocyte migration GO:2000412 2 0.023
glycosyl compound catabolic process GO:1901658 206 0.023
cellular macromolecule catabolic process GO:0044265 206 0.023
regulation of angiogenesis GO:0045765 81 0.022
mature dendritic cell differentiation GO:0097029 3 0.022
regulation of transferase activity GO:0051338 263 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
positive regulation of reproductive process GO:2000243 19 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.022
negative regulation of cell activation GO:0050866 111 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
multicellular organismal homeostasis GO:0048871 164 0.022
cyclic nucleotide metabolic process GO:0009187 59 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
purine containing compound biosynthetic process GO:0072522 70 0.021
axon ensheathment GO:0008366 76 0.021
cell chemotaxis GO:0060326 81 0.021
cell maturation GO:0048469 127 0.021
positive regulation of lymphocyte differentiation GO:0045621 61 0.021
response to organic cyclic compound GO:0014070 198 0.021
action potential GO:0001508 78 0.021
protein secretion GO:0009306 111 0.021
nucleoside metabolic process GO:0009116 246 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
regulation of proteolysis GO:0030162 164 0.020
locomotory behavior GO:0007626 195 0.020
nucleotide biosynthetic process GO:0009165 78 0.020
cellular response to cytokine stimulus GO:0071345 189 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
transmembrane transport GO:0055085 412 0.019
regulation of interleukin 8 production GO:0032677 3 0.019
response to oxidative stress GO:0006979 123 0.019
response to radiation GO:0009314 165 0.019
ribonucleoside metabolic process GO:0009119 245 0.019
b cell activation GO:0042113 161 0.019
rho protein signal transduction GO:0007266 32 0.019
neuronal action potential GO:0019228 54 0.019
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
production of molecular mediator of immune response GO:0002440 103 0.019
b cell differentiation GO:0030183 78 0.019
regulation of protein serine threonine kinase activity GO:0071900 157 0.019
dna metabolic process GO:0006259 303 0.019
carboxylic acid catabolic process GO:0046395 51 0.019
organophosphate biosynthetic process GO:0090407 122 0.019
innate immune response GO:0045087 157 0.019
regulation of osteoclast differentiation GO:0045670 36 0.019
regulation of kinase activity GO:0043549 249 0.019
gland development GO:0048732 330 0.019
germ cell development GO:0007281 185 0.019
regulation of cell cycle GO:0051726 281 0.019
regulation of cell migration GO:0030334 219 0.018
cytokine production involved in immune response GO:0002367 34 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
response to insulin GO:0032868 100 0.018
skeletal muscle organ development GO:0060538 163 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
regulation of leukocyte mediated immunity GO:0002703 104 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
regulation of lymphocyte differentiation GO:0045619 107 0.017
regulation of erk1 and erk2 cascade GO:0070372 71 0.017
regulation of eosinophil migration GO:2000416 2 0.017
ribose phosphate biosynthetic process GO:0046390 59 0.017
positive regulation of cellular amine metabolic process GO:0033240 5 0.017
muscle tissue development GO:0060537 308 0.017
divalent inorganic cation transport GO:0072511 178 0.017
cation homeostasis GO:0055080 212 0.017
eye photoreceptor cell development GO:0042462 31 0.016
methylation GO:0032259 134 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
regulation of system process GO:0044057 200 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
interleukin 12 secretion GO:0072610 3 0.016
response to molecule of bacterial origin GO:0002237 143 0.016
t cell mediated immunity GO:0002456 50 0.016
cellular response to lipopolysaccharide GO:0071222 77 0.016
nucleoside catabolic process GO:0009164 206 0.016
coagulation GO:0050817 78 0.016
positive regulation of interleukin 8 production GO:0032757 2 0.015
neuron apoptotic process GO:0051402 142 0.015
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.015
cofactor metabolic process GO:0051186 80 0.015
anatomical structure homeostasis GO:0060249 145 0.015
cellular response to oxidative stress GO:0034599 76 0.015
positive regulation of cytokine production GO:0001819 174 0.015
ribonucleotide biosynthetic process GO:0009260 59 0.015
positive regulation of t cell activation GO:0050870 101 0.015
regulation of blood pressure GO:0008217 93 0.015
glial cell development GO:0021782 54 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
regulation of body fluid levels GO:0050878 162 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
alpha amino acid catabolic process GO:1901606 18 0.015
macromolecule methylation GO:0043414 120 0.015
negative regulation of leukocyte differentiation GO:1902106 51 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
angiogenesis GO:0001525 201 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.014
nucleotide catabolic process GO:0009166 217 0.014
regulation of organelle organization GO:0033043 289 0.014
nitrogen compound transport GO:0071705 271 0.014
nuclear division GO:0000280 158 0.014
positive regulation of leukocyte differentiation GO:1902107 86 0.014
negative regulation of transferase activity GO:0051348 85 0.014
myeloid cell differentiation GO:0030099 233 0.014
positive regulation of immune effector process GO:0002699 107 0.014
membrane organization GO:0061024 245 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
positive regulation of response to wounding GO:1903036 66 0.014
regulation of t cell mediated immunity GO:0002709 34 0.014
positive regulation of cd4 positive alpha beta t cell proliferation GO:2000563 1 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
organelle fission GO:0048285 170 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
regulation of t helper 2 cell cytokine production GO:2000551 3 0.014
sensory perception of light stimulus GO:0050953 54 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
purine ribonucleotide biosynthetic process GO:0009152 59 0.014
regulation of vasculature development GO:1901342 88 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
myelination GO:0042552 74 0.014
mature natural killer cell chemotaxis GO:0035782 1 0.014
cyclic nucleotide biosynthetic process GO:0009190 44 0.013
t cell activation involved in immune response GO:0002286 43 0.013
positive regulation of eosinophil migration GO:2000418 2 0.013
purine containing compound catabolic process GO:0072523 213 0.013
interspecies interaction between organisms GO:0044419 83 0.013
cytokine secretion GO:0050663 72 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
multicellular organismal response to stress GO:0033555 62 0.013
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.013
muscle cell differentiation GO:0042692 261 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
regulation of innate immune response GO:0045088 91 0.013
negative regulation of lymphocyte differentiation GO:0045620 32 0.013
negative regulation of protein transport GO:0051224 46 0.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.013
spermatid development GO:0007286 108 0.013
positive regulation of protein transport GO:0051222 93 0.013
peptide metabolic process GO:0006518 46 0.013
regulation of secretion GO:0051046 274 0.013
protein activation cascade GO:0072376 19 0.013
regulation of adaptive immune response GO:0002819 90 0.013
negative regulation of growth GO:0045926 99 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
spermatid differentiation GO:0048515 115 0.013
glycoprotein metabolic process GO:0009100 116 0.013
homeostasis of number of cells GO:0048872 210 0.013
regulation of secretion by cell GO:1903530 249 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.013
sequestering of calcium ion GO:0051208 18 0.012
thymocyte migration GO:0072679 2 0.012
regulation of cell projection organization GO:0031344 206 0.012
regulation of lymphocyte mediated immunity GO:0002706 84 0.012
cellular amide metabolic process GO:0043603 58 0.012
cellular lipid metabolic process GO:0044255 323 0.012
hemostasis GO:0007599 78 0.012
cellular response to peptide GO:1901653 92 0.012
cellular response to molecule of bacterial origin GO:0071219 83 0.012
regulation of multi organism process GO:0043900 111 0.012
detection of molecule of bacterial origin GO:0032490 2 0.012
innervation GO:0060384 22 0.012
regulation of myotube differentiation GO:0010830 62 0.012
organic acid catabolic process GO:0016054 51 0.012
regulation of myeloid leukocyte differentiation GO:0002761 58 0.012
glial cell differentiation GO:0010001 131 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
adult behavior GO:0030534 135 0.012
gonad development GO:0008406 141 0.012
cellular amino acid catabolic process GO:0009063 25 0.012
g protein coupled purinergic nucleotide receptor signaling pathway GO:0035589 1 0.012
regulation of interferon gamma production GO:0032649 57 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
epithelium migration GO:0090132 63 0.012
regulation of ion transport GO:0043269 215 0.012
negative regulation of response to wounding GO:1903035 77 0.012
positive regulation of interferon alpha production GO:0032727 4 0.012
blood coagulation GO:0007596 76 0.012
cation transport GO:0006812 399 0.012
negative regulation of interleukin 5 production GO:0032714 4 0.012
apoptotic signaling pathway GO:0097190 306 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
myotube differentiation GO:0014902 105 0.012
wound healing GO:0042060 157 0.011
alpha beta t cell activation GO:0046631 91 0.011
negative regulation of neuron apoptotic process GO:0043524 92 0.011
tissue homeostasis GO:0001894 115 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
organic hydroxy compound biosynthetic process GO:1901617 77 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
negative regulation of endothelial cell migration GO:0010596 4 0.011
protein localization to organelle GO:0033365 185 0.011
regulation of striated muscle cell differentiation GO:0051153 81 0.011
regulation of protein transport GO:0051223 163 0.011
modulation by organism of defense related nitric oxide production in other organism involved in symbiotic interaction GO:0052302 1 0.011
intracellular protein transport GO:0006886 204 0.011
chromatin modification GO:0016568 187 0.011
regulation of blood vessel size GO:0050880 56 0.011
regulation of neuron death GO:1901214 134 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
small molecule catabolic process GO:0044282 71 0.011
regulation of cell motility GO:2000145 236 0.011
regulation of transmembrane transport GO:0034762 128 0.011
regulation of cytokine production involved in immune response GO:0002718 26 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
positive regulation of cell development GO:0010720 237 0.011
natural killer cell activation involved in immune response GO:0002323 10 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
microglial cell activation GO:0001774 3 0.010
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.010
regulation of production of molecular mediator of immune response GO:0002700 65 0.010
regulation of protein secretion GO:0050708 82 0.010
negative regulation of immune effector process GO:0002698 55 0.010
regulation of b cell activation GO:0050864 81 0.010
skin development GO:0043588 220 0.010
muscle fiber development GO:0048747 76 0.010
innate immune response activating signal transduction GO:0002758 50 0.010
morphogenesis of a branching structure GO:0001763 203 0.010
negative regulation of phagocytosis GO:0050765 4 0.010
cytokine mediated signaling pathway GO:0019221 115 0.010
cellular biogenic amine metabolic process GO:0006576 28 0.010
cytoplasmic transport GO:0016482 234 0.010
regulation of cell shape GO:0008360 39 0.010

Tcl1b3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.032
disease of anatomical entity DOID:7 0 0.032
retinal disease DOID:5679 0 0.028
retinal degeneration DOID:8466 0 0.028
sensory system disease DOID:0050155 0 0.028
eye and adnexa disease DOID:1492 0 0.028
nervous system disease DOID:863 0 0.028
eye disease DOID:5614 0 0.028
disease of metabolism DOID:0014667 0 0.020
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
hematopoietic system disease DOID:74 0 0.013
musculoskeletal system disease DOID:17 0 0.011