Mus musculus

75 known processes

Clpx

caseinolytic peptidase X (E.coli)

(Aliases: E330029I21,AU014732)

Clpx biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.078
cellular amino acid metabolic process GO:0006520 103 0.072
regulation of cellular ketone metabolic process GO:0010565 66 0.060
cellular lipid metabolic process GO:0044255 323 0.058
carboxylic acid biosynthetic process GO:0046394 86 0.049
macromolecule catabolic process GO:0009057 281 0.046
organic acid biosynthetic process GO:0016053 86 0.044
male gamete generation GO:0048232 285 0.042
protein catabolic process GO:0030163 221 0.042
spermatogenesis GO:0007283 284 0.041
cellular amine metabolic process GO:0044106 44 0.040
small molecule biosynthetic process GO:0044283 132 0.039
protein processing GO:0016485 163 0.038
glycerolipid metabolic process GO:0046486 122 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
glycosyl compound metabolic process GO:1901657 246 0.036
cation homeostasis GO:0055080 212 0.035
apoptotic signaling pathway GO:0097190 306 0.035
organonitrogen compound catabolic process GO:1901565 264 0.034
regulation of cellular amino acid metabolic process GO:0006521 5 0.034
amine metabolic process GO:0009308 45 0.034
monocarboxylic acid metabolic process GO:0032787 191 0.032
nucleobase containing small molecule metabolic process GO:0055086 352 0.032
regulation of fatty acid biosynthetic process GO:0042304 12 0.032
protein modification by small protein conjugation or removal GO:0070647 207 0.032
negative regulation of cellular protein metabolic process GO:0032269 247 0.032
posttranscriptional regulation of gene expression GO:0010608 155 0.031
organic hydroxy compound metabolic process GO:1901615 203 0.031
negative regulation of fatty acid metabolic process GO:0045922 10 0.031
cellular macromolecule catabolic process GO:0044265 206 0.030
transmembrane transport GO:0055085 412 0.030
cellular nitrogen compound catabolic process GO:0044270 280 0.029
mitochondrion organization GO:0007005 134 0.029
fatty acid biosynthetic process GO:0006633 41 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
fatty acid metabolic process GO:0006631 121 0.027
cellular response to dna damage stimulus GO:0006974 207 0.027
heterocycle catabolic process GO:0046700 280 0.026
modification dependent macromolecule catabolic process GO:0043632 133 0.026
regulation of apoptotic signaling pathway GO:2001233 197 0.026
negative regulation of molecular function GO:0044092 258 0.026
protein maturation GO:0051604 176 0.025
cation transport GO:0006812 399 0.025
negative regulation of intracellular signal transduction GO:1902532 167 0.025
membrane organization GO:0061024 245 0.024
regulation of cellular amine metabolic process GO:0033238 20 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
monocarboxylic acid biosynthetic process GO:0072330 61 0.023
aromatic compound catabolic process GO:0019439 286 0.023
positive regulation of programmed cell death GO:0043068 218 0.023
purine ribonucleotide metabolic process GO:0009150 290 0.023
regulation of organelle organization GO:0033043 289 0.022
intracellular protein transport GO:0006886 204 0.022
positive regulation of cell development GO:0010720 237 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
ion transmembrane transport GO:0034220 361 0.021
cell type specific apoptotic process GO:0097285 268 0.021
nucleoside metabolic process GO:0009116 246 0.021
lipid biosynthetic process GO:0008610 179 0.021
peptidyl amino acid modification GO:0018193 336 0.021
chromatin organization GO:0006325 206 0.021
ubiquitin dependent protein catabolic process GO:0006511 129 0.021
response to peptide GO:1901652 136 0.020
sensory organ morphogenesis GO:0090596 242 0.020
protein ubiquitination GO:0016567 171 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
translation GO:0006412 93 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
small molecule catabolic process GO:0044282 71 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
purine containing compound metabolic process GO:0072521 311 0.019
oxidation reduction process GO:0055114 342 0.019
organophosphate catabolic process GO:0046434 232 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
cellular chemical homeostasis GO:0055082 215 0.019
cellular response to organonitrogen compound GO:0071417 145 0.019
metal ion homeostasis GO:0055065 189 0.019
cellular response to cytokine stimulus GO:0071345 189 0.019
regulation of fatty acid metabolic process GO:0019217 28 0.019
regulation of transferase activity GO:0051338 263 0.019
regulation of cell cycle GO:0051726 281 0.019
ribose phosphate metabolic process GO:0019693 291 0.018
chromatin modification GO:0016568 187 0.018
rna interference GO:0016246 2 0.018
acylglycerol metabolic process GO:0006639 55 0.018
response to radiation GO:0009314 165 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
negative regulation of phosphorus metabolic process GO:0010563 184 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
forebrain development GO:0030900 302 0.018
carbohydrate metabolic process GO:0005975 230 0.018
purine containing compound catabolic process GO:0072523 213 0.018
response to organonitrogen compound GO:0010243 246 0.017
steroid metabolic process GO:0008202 119 0.017
homeostasis of number of cells GO:0048872 210 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
response to peptide hormone GO:0043434 127 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
cation transmembrane transport GO:0098655 266 0.017
nucleotide metabolic process GO:0009117 332 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
cellular homeostasis GO:0019725 240 0.017
meiotic cell cycle GO:0051321 122 0.017
gland development GO:0048732 330 0.017
striated muscle tissue development GO:0014706 293 0.017
negative regulation of protein modification process GO:0031400 163 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.017
blood circulation GO:0008015 195 0.017
cellular response to lipid GO:0071396 145 0.017
organelle fission GO:0048285 170 0.017
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
lipid transport GO:0006869 98 0.016
regulation of lipid metabolic process GO:0019216 118 0.016
regulation of hydrolase activity GO:0051336 246 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
cellular response to peptide hormone stimulus GO:0071375 92 0.015
neutral lipid metabolic process GO:0006638 57 0.015
cellular protein complex assembly GO:0043623 116 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
regulation of membrane potential GO:0042391 192 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
defecation GO:0030421 1 0.015
fat cell differentiation GO:0045444 160 0.015
endomembrane system organization GO:0010256 147 0.015
regulation of protein localization GO:0032880 231 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
organic acid catabolic process GO:0016054 51 0.015
rna processing GO:0006396 105 0.015
skeletal system development GO:0001501 356 0.015
cellular response to peptide GO:1901653 92 0.015
response to acid chemical GO:0001101 111 0.015
cell adhesion GO:0007155 329 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
adult behavior GO:0030534 135 0.014
carboxylic acid catabolic process GO:0046395 51 0.014
protein localization to organelle GO:0033365 185 0.014
camera type eye development GO:0043010 266 0.014
calcium ion homeostasis GO:0055074 127 0.014
cellular protein catabolic process GO:0044257 155 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
cellular ion homeostasis GO:0006873 165 0.014
sensory perception GO:0007600 245 0.014
proteasomal protein catabolic process GO:0010498 98 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
response to oxidative stress GO:0006979 123 0.014
triglyceride metabolic process GO:0006641 51 0.014
positive regulation of cell death GO:0010942 224 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
epithelial cell development GO:0002064 159 0.014
multicellular organismal signaling GO:0035637 91 0.014
calcium ion transport GO:0006816 159 0.014
lipid catabolic process GO:0016042 69 0.014
positive regulation of nervous system development GO:0051962 221 0.014
cellular calcium ion homeostasis GO:0006874 119 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
response to growth factor GO:0070848 198 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
lipid localization GO:0010876 126 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
regulation of ion transport GO:0043269 215 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
mitotic cell cycle GO:0000278 195 0.013
mapk cascade GO:0000165 281 0.013
synaptic transmission GO:0007268 329 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
compound eye development GO:0048749 1 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
male anatomical structure morphogenesis GO:0090598 4 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
response to testosterone GO:0033574 3 0.013
response to organic cyclic compound GO:0014070 198 0.013
protein targeting GO:0006605 143 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
anion transport GO:0006820 177 0.013
alcohol metabolic process GO:0006066 116 0.013
regulation of hormone levels GO:0010817 211 0.013
regulation of kinase activity GO:0043549 249 0.013
nucleoside catabolic process GO:0009164 206 0.013
modification dependent protein catabolic process GO:0019941 133 0.012
sodium ion transport GO:0006814 73 0.012
regulation of proteolysis GO:0030162 164 0.012
negative regulation of transferase activity GO:0051348 85 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.012
divalent metal ion transport GO:0070838 172 0.012
nitrogen compound transport GO:0071705 271 0.012
spermatid differentiation GO:0048515 115 0.012
action potential GO:0001508 78 0.012
male genitalia morphogenesis GO:0048808 4 0.012
spermatid development GO:0007286 108 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
regulation of cell projection organization GO:0031344 206 0.012
meiotic nuclear division GO:0007126 115 0.012
cell growth GO:0016049 130 0.012
ossification GO:0001503 216 0.012
cellular response to insulin stimulus GO:0032869 78 0.012
nuclear division GO:0000280 158 0.012
muscle cell differentiation GO:0042692 261 0.012
regulation of protein catabolic process GO:0042176 108 0.012
divalent inorganic cation transport GO:0072511 178 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
regulation of protein processing GO:0070613 96 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
organic hydroxy compound biosynthetic process GO:1901617 77 0.011
neuron death GO:0070997 154 0.011
organ regeneration GO:0031100 2 0.011
positive regulation of protein modification process GO:0031401 299 0.011
response to light stimulus GO:0009416 135 0.011
lipid homeostasis GO:0055088 63 0.011
regulation of protein kinase activity GO:0045859 232 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
organic acid transport GO:0015849 101 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
response to inorganic substance GO:0010035 96 0.011
regulation of mapk cascade GO:0043408 248 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.011
protein import GO:0017038 101 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
histone modification GO:0016570 159 0.011
fatty acid derivative metabolic process GO:1901568 33 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
regulation of androgen receptor signaling pathway GO:0060765 3 0.011
response to transforming growth factor beta GO:0071559 88 0.011
establishment of organelle localization GO:0051656 122 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
sterol metabolic process GO:0016125 58 0.011
maintenance of location GO:0051235 89 0.011
regulation of cytokine production GO:0001817 266 0.011
steroid biosynthetic process GO:0006694 47 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
circulatory system process GO:0003013 197 0.011
cellular response to acid chemical GO:0071229 68 0.011
meiotic cell cycle process GO:1903046 77 0.011
germ cell development GO:0007281 185 0.011
asymmetric stem cell division GO:0098722 3 0.011
regulation of protein maturation GO:1903317 96 0.011
muscle tissue development GO:0060537 308 0.011
endocytosis GO:0006897 168 0.011
anatomical structure homeostasis GO:0060249 145 0.011
nucleotide catabolic process GO:0009166 217 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
organic anion transport GO:0015711 137 0.010
carboxylic acid transport GO:0046942 100 0.010
alcohol biosynthetic process GO:0046165 43 0.010
er nucleus signaling pathway GO:0006984 27 0.010
regulation of neuron projection development GO:0010975 169 0.010
glycoprotein metabolic process GO:0009100 116 0.010
negative regulation of organelle organization GO:0010639 90 0.010
mrna metabolic process GO:0016071 84 0.010
transmission of nerve impulse GO:0019226 76 0.010
regulation of cytoskeleton organization GO:0051493 122 0.010
response to lipopolysaccharide GO:0032496 128 0.010
regulation of lymphocyte activation GO:0051249 240 0.010
negative regulation of kinase activity GO:0033673 81 0.010
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010
regulation of fat cell differentiation GO:0045598 81 0.010
response to insulin GO:0032868 100 0.010
tissue homeostasis GO:0001894 115 0.010
skeletal muscle organ development GO:0060538 163 0.010
myeloid cell differentiation GO:0030099 233 0.010
establishment of protein localization to organelle GO:0072594 118 0.010
cytoplasmic transport GO:0016482 234 0.010
positive regulation of transferase activity GO:0051347 167 0.010

Clpx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
cancer DOID:162 0 0.018
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
disease of metabolism DOID:0014667 0 0.017
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.011
inherited metabolic disorder DOID:655 0 0.010