Mus musculus

34 known processes

Lox

lysyl oxidase

(Aliases: TSC-160,AI893619)

Lox biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
extracellular matrix organization GO:0030198 147 0.998
collagen fibril organization GO:0030199 32 0.992
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.977
regulation of removal of superoxide radicals GO:2000121 4 0.965
elastic fiber assembly GO:0048251 4 0.960
cellular response to oxygen radical GO:0071450 14 0.959
cellular response to growth factor stimulus GO:0071363 197 0.957
trabecula formation GO:0060343 24 0.950
skeletal system morphogenesis GO:0048705 203 0.949
connective tissue development GO:0061448 179 0.934
Zebrafish
negative regulation of cell motility GO:2000146 61 0.924
extracellular structure organization GO:0043062 148 0.920
regulation of cell migration GO:0030334 219 0.911
negative regulation of cell migration GO:0030336 59 0.899
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.897
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.888
cell substrate adhesion GO:0031589 130 0.879
skeletal system development GO:0001501 356 0.870
Zebrafish
removal of superoxide radicals GO:0019430 12 0.857
growth plate cartilage development GO:0003417 14 0.857
cell chemotaxis GO:0060326 81 0.840
blood vessel morphogenesis GO:0048514 285 0.825
cell adhesion GO:0007155 329 0.825
response to growth factor GO:0070848 198 0.822
chondrocyte differentiation GO:0002062 72 0.810
respiratory system development GO:0060541 190 0.779
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.776
cartilage development GO:0051216 140 0.763
Zebrafish
response to reactive oxygen species GO:0000302 56 0.739
bone development GO:0060348 120 0.720
trabecula morphogenesis GO:0061383 40 0.713
respiratory tube development GO:0030323 167 0.708
regulation of reactive oxygen species metabolic process GO:2000377 40 0.707
development of primary female sexual characteristics GO:0046545 73 0.707
regulation of response to oxidative stress GO:1902882 19 0.704
regulation of cell motility GO:2000145 236 0.680
hair follicle morphogenesis GO:0031069 29 0.676
regulation of cell adhesion GO:0030155 154 0.666
endochondral bone growth GO:0003416 19 0.665
negative regulation of apoptotic signaling pathway GO:2001234 104 0.662
small gtpase mediated signal transduction GO:0007264 97 0.641
response to oxidative stress GO:0006979 123 0.638
cartilage condensation GO:0001502 18 0.637
regulation of angiogenesis GO:0045765 81 0.624
regulation of vasculature development GO:1901342 88 0.621
ovarian follicle development GO:0001541 40 0.620
muscle tissue development GO:0060537 308 0.618
positive regulation of cytokine production GO:0001819 174 0.615
inflammatory response GO:0006954 244 0.602
stress response to metal ion GO:0097501 3 0.599
limb development GO:0060173 166 0.580
bone trabecula morphogenesis GO:0061430 12 0.569
extrinsic apoptotic signaling pathway GO:0097191 126 0.562
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.553
positive regulation of cell migration GO:0030335 109 0.546
cellular response to superoxide GO:0071451 14 0.545
lung development GO:0030324 164 0.536
cellular response to oxidative stress GO:0034599 76 0.525
positive regulation of cell motility GO:2000147 116 0.514
cardiac chamber development GO:0003205 108 0.511
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.510
appendage morphogenesis GO:0035107 149 0.509
regulation of renal output by angiotensin GO:0002019 2 0.504
skeletal muscle organ development GO:0060538 163 0.490
cell aggregation GO:0098743 18 0.484
positive regulation of interferon gamma secretion GO:1902715 3 0.478
skin development GO:0043588 220 0.473
response to organic cyclic compound GO:0014070 198 0.472
bone resorption GO:0045453 38 0.452
ossification GO:0001503 216 0.451
regulation of apoptotic signaling pathway GO:2001233 197 0.450
response to transforming growth factor beta GO:0071559 88 0.447
regionalization GO:0003002 337 0.443
regulation of eosinophil migration GO:2000416 2 0.442
chondrocyte development GO:0002063 24 0.438
striated muscle tissue development GO:0014706 293 0.437
homeostasis of number of cells GO:0048872 210 0.434
negative regulation of molecular function GO:0044092 258 0.430
negative regulation of vasoconstriction GO:0045906 2 0.418
epidermis morphogenesis GO:0048730 33 0.406
endochondral bone morphogenesis GO:0060350 50 0.398
positive regulation of hydrolase activity GO:0051345 148 0.393
sequestering of bmp in extracellular matrix GO:0035582 3 0.391
cardiac muscle tissue development GO:0048738 130 0.386
regulation of cellular response to oxidative stress GO:1900407 19 0.381
response to oxygen levels GO:0070482 62 0.375
face morphogenesis GO:0060325 29 0.373
response to decreased oxygen levels GO:0036293 59 0.368
angiogenesis GO:0001525 201 0.367
stem cell differentiation GO:0048863 268 0.362
ameboidal type cell migration GO:0001667 128 0.357
epidermis development GO:0008544 187 0.356
negative regulation of endothelial cell migration GO:0010596 4 0.354
anatomical structure homeostasis GO:0060249 145 0.351
regulation of fibrinolysis GO:0051917 1 0.349
glycoprotein metabolic process GO:0009100 116 0.339
renal system development GO:0072001 225 0.336
molting cycle GO:0042303 90 0.323
regulation of secretion GO:0051046 274 0.320
positive regulation of cell substrate adhesion GO:0010811 47 0.316
negative regulation of cell substrate adhesion GO:0010812 16 0.306
positive regulation of cell adhesion GO:0045785 80 0.297
mononuclear cell migration GO:0071674 8 0.292
regulation of gastrulation GO:0010470 16 0.290
regulation of cytokine production GO:0001817 266 0.283
epithelial cell migration GO:0010631 63 0.280
embryonic skeletal system development GO:0048706 120 0.277
branching morphogenesis of an epithelial tube GO:0048754 159 0.275
negative regulation of bmp signaling pathway GO:0030514 35 0.275
positive regulation of proteolysis GO:0045862 85 0.274
response to organonitrogen compound GO:0010243 246 0.271
phospholipase c activating angiotensin activated signaling pathway GO:0086097 1 0.269
stem cell development GO:0048864 219 0.266
cellular response to acid chemical GO:0071229 68 0.263
protein catabolic process GO:0030163 221 0.263
macromolecule catabolic process GO:0009057 281 0.258
regulation of cell substrate adhesion GO:0010810 73 0.257
antibacterial peptide biosynthetic process GO:0002780 2 0.255
negative regulation of vasculature development GO:1901343 26 0.253
heart morphogenesis GO:0003007 178 0.252
response to oxygen radical GO:0000305 16 0.244
forebrain development GO:0030900 302 0.243
positive regulation of thymocyte migration GO:2000412 2 0.241
cytokine secretion GO:0050663 72 0.239
positive regulation of angiogenesis GO:0045766 46 0.234
female gonad development GO:0008585 71 0.233
bone morphogenesis GO:0060349 78 0.232
regulation of cellular component size GO:0032535 121 0.229
female sex differentiation GO:0046660 84 0.225
intrinsic apoptotic signaling pathway in response to osmotic stress GO:0008627 2 0.216
regulation of lung blood pressure GO:0014916 2 0.214
antibacterial peptide secretion GO:0002779 1 0.210
regulation of superoxide metabolic process GO:0090322 8 0.207
regulation of sphingolipid biosynthetic process GO:0090153 1 0.207
regulation of macrophage chemotaxis GO:0010758 8 0.206
defense response to bacterium GO:0042742 119 0.206
reactive oxygen species metabolic process GO:0072593 84 0.204
epithelial tube morphogenesis GO:0060562 303 0.203
ear morphogenesis GO:0042471 118 0.202
cytokine production GO:0001816 319 0.202
intussusceptive angiogenesis GO:0002041 2 0.200
activation of mapk activity GO:0000187 59 0.200
ras protein signal transduction GO:0007265 77 0.199
renal tubule morphogenesis GO:0061333 72 0.196
apoptotic signaling pathway GO:0097190 306 0.195
hair follicle development GO:0001942 85 0.195
positive regulation of kinase activity GO:0033674 155 0.194
regulation of cellular component biogenesis GO:0044087 181 0.193
regulation of blood vessel size GO:0050880 56 0.192
tissue migration GO:0090130 68 0.185
granulocyte chemotaxis GO:0071621 39 0.185
epithelium migration GO:0090132 63 0.185
embryonic organ morphogenesis GO:0048562 276 0.185
regulation of transferase activity GO:0051338 263 0.181
response to interleukin 1 GO:0070555 11 0.180
cell matrix adhesion GO:0007160 68 0.179
regulation of secretion by cell GO:1903530 249 0.178
telencephalon development GO:0021537 186 0.175
regulation of cell adhesion mediated by integrin GO:0033628 13 0.174
regulation of actin filament based process GO:0032970 99 0.173
negative regulation of cell proliferation GO:0008285 296 0.171
regulation of cytokine secretion GO:0050707 61 0.171
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.171
endothelial cell migration GO:0043542 44 0.166
biomineral tissue development GO:0031214 64 0.165
single organism cell adhesion GO:0098602 156 0.164
regulation of cartilage development GO:0061035 44 0.164
positive regulation of secretion by cell GO:1903532 114 0.164
positive regulation of mapk cascade GO:0043410 170 0.163
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.159
basement membrane organization GO:0071711 8 0.157
mesenchyme development GO:0060485 152 0.156
epithelial cell proliferation GO:0050673 174 0.155
appendage development GO:0048736 166 0.155
ovarian cumulus expansion GO:0001550 1 0.154
axonogenesis GO:0007409 274 0.153
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.153
cell adhesion mediated by integrin GO:0033627 18 0.152
odontogenesis GO:0042476 78 0.152
regulation of tolerance induction to self antigen GO:0002649 1 0.151
digestive system development GO:0055123 200 0.150
response to peptide GO:1901652 136 0.149
telencephalon cell migration GO:0022029 55 0.149
tissue homeostasis GO:0001894 115 0.148
positive regulation of nitric oxide synthase activity GO:0051000 2 0.148
smoothened signaling pathway GO:0007224 105 0.148
endoderm development GO:0007492 45 0.147
positive regulation of bone remodeling GO:0046852 13 0.145
organ growth GO:0035265 117 0.145
multi multicellular organism process GO:0044706 109 0.145
negative regulation of fibrinolysis GO:0051918 1 0.141
ovulation cycle GO:0042698 59 0.141
positive regulation of macrophage chemotaxis GO:0010759 5 0.139
heart trabecula morphogenesis GO:0061384 26 0.139
muscle cell apoptotic process GO:0010657 18 0.139
positive regulation of cell death GO:0010942 224 0.135
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.134
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.132
long term synaptic potentiation GO:0060291 25 0.131
fibrinolysis GO:0042730 3 0.130
circulatory system process GO:0003013 197 0.130
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.130
release of cytochrome c from mitochondria GO:0001836 23 0.127
positive regulation of metalloenzyme activity GO:0048554 3 0.127
tryptophan metabolic process GO:0006568 4 0.127
leukocyte chemotaxis GO:0030595 69 0.125
antimicrobial peptide secretion GO:0002776 1 0.125
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress GO:1902218 1 0.125
amine metabolic process GO:0009308 45 0.125
regulation of cellular response to growth factor stimulus GO:0090287 82 0.123
actin filament polymerization GO:0030041 44 0.122
positive regulation of protein secretion GO:0050714 52 0.121
cardiac muscle hypertrophy GO:0003300 23 0.120
lung alveolus development GO:0048286 45 0.120
heart trabecula formation GO:0060347 14 0.120
regulation of protein kinase activity GO:0045859 232 0.119
kidney development GO:0001822 213 0.118
negative regulation of angiogenesis GO:0016525 25 0.118
regulation of cytoskeleton organization GO:0051493 122 0.117
limb morphogenesis GO:0035108 149 0.116
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.116
negative regulation of endothelial cell differentiation GO:0045602 2 0.115
negative regulation of macrophage chemotaxis GO:0010760 1 0.114
multicellular organismal homeostasis GO:0048871 164 0.114
muscle tissue morphogenesis GO:0060415 53 0.114
negative regulation of cell adhesion mediated by integrin GO:0033629 2 0.114
renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure GO:0003072 5 0.114
artery development GO:0060840 53 0.114
indolalkylamine metabolic process GO:0006586 4 0.114
engulfment of apoptotic cell GO:0043652 3 0.113
notochord development GO:0030903 20 0.113
negative regulation of smooth muscle cell apoptotic process GO:0034392 1 0.112
response to hypoxia GO:0001666 58 0.111
fibril organization GO:0097435 2 0.111
endoderm formation GO:0001706 20 0.111
cell recognition GO:0008037 83 0.111
activation of mapkk activity GO:0000186 15 0.108
peripheral nervous system axon regeneration GO:0014012 2 0.108
embryonic skeletal system morphogenesis GO:0048704 91 0.107
regulation of ras protein signal transduction GO:0046578 114 0.105
regulation of chemotaxis GO:0050920 53 0.104
regulation of peptidase activity GO:0052547 96 0.104
negative regulation of cell adhesion GO:0007162 45 0.103
extracellular matrix assembly GO:0085029 12 0.103
cdc42 protein signal transduction GO:0032488 0 0.102
renin angiotensin regulation of aldosterone production GO:0002018 3 0.100
tyrosine metabolic process GO:0006570 4 0.100
regulation of phospholipase a2 activity GO:0032429 3 0.100
ribonucleoside triphosphate metabolic process GO:0009199 220 0.100
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1902239 1 0.099
steroid metabolic process GO:0008202 119 0.099
regulation of thymocyte migration GO:2000410 2 0.099
neural plate mediolateral regionalization GO:0021998 1 0.098
positive regulation of bone resorption GO:0045780 13 0.097
camera type eye development GO:0043010 266 0.097
regulation of epithelial cell migration GO:0010632 35 0.097
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1902238 1 0.096
sprouting angiogenesis GO:0002040 26 0.096
regulation of bmp signaling pathway GO:0030510 60 0.096
granulocyte migration GO:0097530 43 0.096
regulation of inflammatory response GO:0050727 147 0.095
regulation of chondrocyte differentiation GO:0032330 33 0.094
positive regulation of phospholipase activity GO:0010518 3 0.094
positive regulation of lipid metabolic process GO:0045834 40 0.092
negative regulation of heart rate GO:0010459 4 0.091
regulation of cellular ketone metabolic process GO:0010565 66 0.091
regulation of response to reactive oxygen species GO:1901031 9 0.089
positive regulation of monooxygenase activity GO:0032770 2 0.088
fused antrum stage GO:0048165 1 0.087
superoxide metabolic process GO:0006801 27 0.086
positive regulation of protein kinase b signaling GO:0051897 32 0.086
cellular response to cytokine stimulus GO:0071345 189 0.085
positive regulation of transferase activity GO:0051347 167 0.084
cell type specific apoptotic process GO:0097285 268 0.084
cardiac ventricle development GO:0003231 83 0.083
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1990127 1 0.083
digestive tract development GO:0048565 190 0.083
negative regulation of nervous system development GO:0051961 156 0.082
morphogenesis of a branching structure GO:0001763 203 0.081
sa node cell action potential GO:0086015 4 0.081
macrophage chemotaxis GO:0048246 14 0.081
hormone secretion GO:0046879 128 0.081
forebrain cell migration GO:0021885 58 0.080
response to acid chemical GO:0001101 111 0.078
neuron migration GO:0001764 122 0.078
negative regulation of chemotaxis GO:0050922 11 0.077
negative regulation of blood vessel morphogenesis GO:2000181 25 0.077
positive regulation of tolerance induction to self antigen GO:0002651 1 0.077
positive regulation of macrophage activation GO:0043032 10 0.076
regulation of neuron differentiation GO:0045664 281 0.076
response to inorganic substance GO:0010035 96 0.076
positive regulation of eosinophil migration GO:2000418 2 0.075
chemotaxis GO:0006935 247 0.074
neural crest cell development GO:0014032 48 0.074
mesonephros development GO:0001823 97 0.074
urogenital system development GO:0001655 261 0.074
rhythmic process GO:0048511 174 0.074
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.073
positive regulation of apoptotic process GO:0043065 217 0.073
regulation of bone mineralization GO:0030500 31 0.073
negative regulation of fatty acid transport GO:2000192 1 0.072
vascular wound healing GO:0061042 3 0.072
protein heterotrimerization GO:0070208 8 0.072
nitric oxide mediated signal transduction GO:0007263 4 0.071
positive regulation of programmed cell death GO:0043068 218 0.071
hair cycle GO:0042633 90 0.071
response to estrogen GO:0043627 24 0.070
regulation of protein catabolic process GO:0042176 108 0.069
extracellular matrix dependent thymocyte migration GO:0072680 1 0.069
lipid transport GO:0006869 98 0.069
protein polymerization GO:0051258 57 0.069
negative regulation of cartilage development GO:0061037 17 0.068
regulation of organelle organization GO:0033043 289 0.068
receptor recycling GO:0001881 11 0.068
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.068
cellular amino acid metabolic process GO:0006520 103 0.068
regulation of fat cell differentiation GO:0045598 81 0.067
mesonephric tubule morphogenesis GO:0072171 63 0.066
gland development GO:0048732 330 0.066
defense response to gram positive bacterium GO:0050830 50 0.066
physiological cardiac muscle hypertrophy GO:0003301 3 0.066
regulation of ossification GO:0030278 112 0.066
positive regulation of nervous system development GO:0051962 221 0.065
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.064
negative regulation of neuron differentiation GO:0045665 101 0.064
anatomical structure maturation GO:0071695 49 0.064
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.064
positive regulation of behavior GO:0048520 40 0.064
response to hyperoxia GO:0055093 2 0.063
positive regulation of cell projection organization GO:0031346 95 0.063
regulation of rho protein signal transduction GO:0035023 71 0.063
phenol containing compound biosynthetic process GO:0046189 21 0.062
peptidyl amino acid modification GO:0018193 336 0.062
calcium ion homeostasis GO:0055074 127 0.062
neural crest cell migration GO:0001755 32 0.061
positive regulation of tissue remodeling GO:0034105 19 0.061
membrane lipid biosynthetic process GO:0046467 32 0.061
synaptic transmission GO:0007268 329 0.060
cellular response to inorganic substance GO:0071241 37 0.060
bone mineralization GO:0030282 54 0.060
negative regulation of growth GO:0045926 99 0.059
mesenchymal cell differentiation GO:0048762 107 0.059
intrinsic apoptotic signaling pathway GO:0097193 132 0.059
superoxide anion generation GO:0042554 11 0.059
response to metal ion GO:0010038 47 0.059
single organismal cell cell adhesion GO:0016337 131 0.059
cell growth involved in cardiac muscle cell development GO:0061049 3 0.059
thymocyte migration GO:0072679 2 0.059
response to dexamethasone GO:0071548 8 0.058
cellular protein complex assembly GO:0043623 116 0.058
regulation of homeostatic process GO:0032844 182 0.058
negative regulation of epithelial cell migration GO:0010633 9 0.057
cellular response to lipid GO:0071396 145 0.057
positive regulation of cytokine secretion GO:0050715 41 0.057
skin morphogenesis GO:0043589 38 0.057
cellular response to nitric oxide GO:0071732 4 0.057
transmembrane transport GO:0055085 412 0.057
regulation of biomineral tissue development GO:0070167 33 0.056
ear development GO:0043583 200 0.056
negative regulation of cell development GO:0010721 169 0.056
sequestering of extracellular ligand from receptor GO:0035581 6 0.055
regulation of proteolysis GO:0030162 164 0.055
cellular response to amino acid stimulus GO:0071230 29 0.055
amide transport GO:0042886 138 0.055
sensory organ morphogenesis GO:0090596 242 0.054
regulation of anatomical structure size GO:0090066 178 0.054
retinal blood vessel morphogenesis GO:0061304 3 0.054
bmp signaling pathway GO:0030509 93 0.054
eosinophil migration GO:0072677 3 0.054
myeloid leukocyte migration GO:0097529 57 0.054
positive regulation of cellular amine metabolic process GO:0033240 5 0.053
negative regulation of anti mullerian hormone signaling pathway GO:1902613 1 0.053
peptide cross linking GO:0018149 10 0.052
endothelial cell proliferation GO:0001935 27 0.052
organic anion transport GO:0015711 137 0.052
leukocyte homeostasis GO:0001776 79 0.052
regulation of superoxide anion generation GO:0032928 4 0.052
negative regulation of insulin secretion GO:0046676 14 0.051
axon guidance GO:0007411 141 0.051
bone trabecula formation GO:0060346 9 0.051
locomotory behavior GO:0007626 195 0.051
regulation of establishment of protein localization GO:0070201 181 0.050
negative regulation of intracellular signal transduction GO:1902532 167 0.050
alpha beta t cell activation GO:0046631 91 0.050
regulation of lipase activity GO:0060191 15 0.050
regulation of cardiac muscle tissue growth GO:0055021 26 0.049
sphingolipid biosynthetic process GO:0030148 26 0.049
cellular response to hormone stimulus GO:0032870 150 0.049
response to amino acid GO:0043200 37 0.049
development of primary sexual characteristics GO:0045137 143 0.049
response to superoxide GO:0000303 16 0.049
purine containing compound metabolic process GO:0072521 311 0.048
positive regulation of neuron projection development GO:0010976 79 0.047
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.047
placenta development GO:0001890 140 0.047
cellular response to corticosteroid stimulus GO:0071384 13 0.047
divalent inorganic cation transport GO:0072511 178 0.046
cardiac muscle tissue morphogenesis GO:0055008 44 0.046
foramen ovale closure GO:0035922 1 0.046
positive regulation of protein kinase activity GO:0045860 144 0.046
regulation of muscle tissue development GO:1901861 97 0.046
regulation of mapk cascade GO:0043408 248 0.045
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 11 0.045
regulation of endopeptidase activity GO:0052548 89 0.045
regulation of epithelial cell proliferation GO:0050678 141 0.045
negative regulation of endothelial cell proliferation GO:0001937 8 0.045
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.045
ventricular cardiac muscle tissue development GO:0003229 38 0.044
positive regulation of protein phosphorylation GO:0001934 242 0.044
multicellular organismal catabolic process GO:0044243 7 0.044
digestive tract morphogenesis GO:0048546 147 0.044
morphogenesis of a branching epithelium GO:0061138 193 0.044
signal transduction in absence of ligand GO:0038034 55 0.044
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.043
antibacterial peptide production GO:0002778 2 0.043
endothelium development GO:0003158 45 0.043
response to copper ion GO:0046688 3 0.043
cerebral cortex cell migration GO:0021795 44 0.042
rho protein signal transduction GO:0007266 32 0.042
tissue remodeling GO:0048771 102 0.042
cgmp mediated signaling GO:0019934 3 0.042
renal system process GO:0003014 48 0.042
maintenance of protein location in nucleus GO:0051457 2 0.042
mesoderm structural organization GO:0048338 1 0.042
organ regeneration GO:0031100 2 0.042
carbohydrate derivative biosynthetic process GO:1901137 183 0.041
placenta blood vessel development GO:0060674 31 0.041
dibenzo p dioxin metabolic process GO:0018894 1 0.041
phagocytosis GO:0006909 66 0.041
response to bmp GO:0071772 14 0.041
contact inhibition GO:0060242 3 0.041
positive regulation of protein modification process GO:0031401 299 0.041
positive regulation of cellular component biogenesis GO:0044089 94 0.041
regulation of hormone levels GO:0010817 211 0.041
response to steroid hormone GO:0048545 56 0.041
epithelial to mesenchymal transition GO:0001837 47 0.040
regulation of vasoconstriction GO:0019229 14 0.040
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.040
positive regulation of jak stat cascade GO:0046427 22 0.040
cytosolic calcium ion homeostasis GO:0051480 70 0.040
positive regulation of b cell tolerance induction GO:0002663 2 0.040
apoptotic mitochondrial changes GO:0008637 48 0.040
regulation of generation of precursor metabolites and energy GO:0043467 38 0.040
positive regulation of chemotaxis GO:0050921 38 0.039
smooth muscle contraction GO:0006939 44 0.039
positive regulation of adiponectin secretion GO:0070165 1 0.039
purine ribonucleotide metabolic process GO:0009150 290 0.039
glomerular mesangial cell development GO:0072144 3 0.039
wound healing GO:0042060 157 0.039
protein oligomerization GO:0051259 67 0.039
regulation of wound healing GO:0061041 40 0.039
cellular response to organic cyclic compound GO:0071407 87 0.039
cellular response to bmp stimulus GO:0071773 14 0.039
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.039
astrocyte cell migration GO:0043615 3 0.039
glomerular mesangial cell differentiation GO:0072008 3 0.039
negative regulation of ossification GO:0030279 49 0.038
regulation of tissue remodeling GO:0034103 38 0.038
blood circulation GO:0008015 195 0.038
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.038
regulation of body fluid levels GO:0050878 162 0.038
mature dendritic cell differentiation GO:0097029 3 0.038
positive regulation of response to wounding GO:1903036 66 0.038
regulation of organ morphogenesis GO:2000027 144 0.038
anatomical structure arrangement GO:0048532 20 0.038
regulation of blood pressure GO:0008217 93 0.038
protein secretion GO:0009306 111 0.038
neutrophil migration GO:1990266 37 0.038
oocyte axis specification GO:0007309 2 0.037
cellular ketone metabolic process GO:0042180 84 0.037
regulation of phosphatidylcholine catabolic process GO:0010899 2 0.037
regulation of bone resorption GO:0045124 24 0.037
positive regulation of wound healing GO:0090303 17 0.037
heart growth GO:0060419 45 0.037
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
regulation of actin cytoskeleton organization GO:0032956 84 0.036
regulation of ceramide biosynthetic process GO:2000303 1 0.036
regulation of neuron death GO:1901214 134 0.036
pattern specification involved in metanephros development GO:0072268 4 0.036
cellular response to glucocorticoid stimulus GO:0071385 13 0.036

Lox disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
heart disease DOID:114 0 0.802
disease of anatomical entity DOID:7 0 0.802
cardiovascular system disease DOID:1287 0 0.802
musculoskeletal system disease DOID:17 0 0.434
connective tissue disease DOID:65 0 0.434
sensory system disease DOID:0050155 0 0.146
eye and adnexa disease DOID:1492 0 0.146
nervous system disease DOID:863 0 0.146
eye disease DOID:5614 0 0.146
retinal disease DOID:5679 0 0.091
retinal degeneration DOID:8466 0 0.091
disease of metabolism DOID:0014667 0 0.070
glaucoma DOID:1686 0 0.061
inherited metabolic disorder DOID:655 0 0.053
metal metabolism disorder DOID:896 0 0.047