|
|
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation
|
GO:2000721 |
2 |
0.940
|
|
|
|
microglia development
|
GO:0014005 |
2 |
0.897
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.886
|
Mouse |
|
|
coagulation
|
GO:0050817 |
78 |
0.882
|
|
|
|
negative regulation of rho protein signal transduction
|
GO:0035024 |
7 |
0.881
|
Mouse |
|
|
organelle assembly
|
GO:0070925 |
177 |
0.836
|
Mouse |
|
|
blood coagulation
|
GO:0007596 |
76 |
0.811
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.809
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.803
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.802
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.780
|
Mouse |
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
14 |
0.763
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.736
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.733
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.721
|
Mouse |
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.713
|
Mouse |
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.709
|
|
|
|
blood vessel remodeling
|
GO:0001974 |
33 |
0.709
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.709
|
Mouse |
|
|
dendritic spine maintenance
|
GO:0097062 |
4 |
0.690
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.690
|
Mouse |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.679
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.673
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.670
|
|
|
|
salivary gland development
|
GO:0007431 |
37 |
0.657
|
Fly |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.649
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.648
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.642
|
Worm |
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.640
|
Mouse |
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.638
|
Mouse |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.635
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.631
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.605
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.600
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.596
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.592
|
Mouse |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.583
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.578
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.578
|
Mouse |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.577
|
Mouse |
|
|
wound healing
|
GO:0042060 |
157 |
0.577
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.564
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.562
|
Mouse Fly |
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.561
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.560
|
Mouse Fly |
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.554
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.553
|
Mouse |
|
|
negative regulation of hemostasis
|
GO:1900047 |
11 |
0.551
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.550
|
|
|
|
regulation of engulfment of apoptotic cell
|
GO:1901074 |
2 |
0.545
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.544
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.538
|
Fly |
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
43 |
0.535
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.529
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.523
|
Mouse Worm |
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.515
|
Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.512
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.511
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.510
|
Mouse Fly |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.493
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.492
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.489
|
Mouse |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.484
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.479
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.479
|
Mouse Worm |
|
|
cell cell adhesion via plasma membrane adhesion molecules
|
GO:0098742 |
40 |
0.476
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.470
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.470
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.469
|
Mouse |
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.467
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.465
|
Mouse |
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.456
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.455
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.454
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.454
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.451
|
|
|
|
endothelial cell migration
|
GO:0043542 |
44 |
0.441
|
Mouse |
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.439
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.435
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.429
|
Mouse Fly |
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.429
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.425
|
Mouse |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.416
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.410
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.403
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.401
|
Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.396
|
Mouse |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.392
|
Fly |
|
|
bone resorption
|
GO:0045453 |
38 |
0.391
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.386
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.384
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.381
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.381
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.370
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.367
|
Mouse |
|
|
regionalization
|
GO:0003002 |
337 |
0.364
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.364
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.363
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.359
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.353
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.351
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.349
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.347
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.347
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.344
|
Mouse Fly |
|
|
kidney development
|
GO:0001822 |
213 |
0.338
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.338
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.337
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.336
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.334
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.331
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.331
|
|
|
|
regulation of tissue remodeling
|
GO:0034103 |
38 |
0.328
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.323
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.316
|
Mouse |
|
|
fibrinolysis
|
GO:0042730 |
3 |
0.310
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.310
|
Fly |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.305
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.303
|
|
|
|
leukocyte migration involved in inflammatory response
|
GO:0002523 |
7 |
0.302
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.302
|
|
|
|
positive regulation of bone resorption
|
GO:0045780 |
13 |
0.301
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.300
|
Mouse |
|
|
phagocytosis
|
GO:0006909 |
66 |
0.297
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.296
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.296
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.295
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.293
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.289
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.289
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.288
|
|
|
|
negative regulation of coagulation
|
GO:0050819 |
11 |
0.287
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.283
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.283
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.282
|
Mouse |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.282
|
Fly |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.282
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.279
|
Worm |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.278
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.276
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.276
|
|
|
|
exocrine system development
|
GO:0035272 |
45 |
0.274
|
Fly |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.274
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.267
|
Worm |
|
|
cell cell adhesion
|
GO:0098609 |
41 |
0.267
|
|
|
|
positive regulation of bone remodeling
|
GO:0046852 |
13 |
0.264
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.257
|
|
|
|
exploration behavior
|
GO:0035640 |
21 |
0.256
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.254
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.252
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.249
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.245
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.244
|
Fly |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.242
|
Mouse |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.240
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.239
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.239
|
Mouse |
|
|
positive regulation of engulfment of apoptotic cell
|
GO:1901076 |
1 |
0.237
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.235
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.235
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.234
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.232
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.231
|
Fly |
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.231
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.230
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.225
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.224
|
|
|
|
negative regulation of wound healing
|
GO:0061045 |
14 |
0.221
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.218
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.217
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.217
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.216
|
Mouse Fly |
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.214
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.212
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.212
|
|
|
|
regulation of bone resorption
|
GO:0045124 |
24 |
0.211
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.206
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.203
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.201
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.199
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.197
|
|
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.194
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.193
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.193
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.192
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.191
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
69 |
0.191
|
Mouse |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.188
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.187
|
|
|
|
regulation of coagulation
|
GO:0050818 |
31 |
0.184
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.183
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
28 |
0.180
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.179
|
Mouse |
|
|
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules
|
GO:0007157 |
20 |
0.179
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.177
|
|
|
|
smooth muscle tissue development
|
GO:0048745 |
22 |
0.176
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.176
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.175
|
Fly |
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.175
|
Mouse Fly |
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.174
|
Fly |
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.174
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.174
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.173
|
Fly |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.173
|
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
15 |
0.170
|
Fly |
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.170
|
Mouse |
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.167
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.167
|
|
|
|
myofibril assembly
|
GO:0030239 |
34 |
0.166
|
Mouse |
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.166
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.165
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.165
|
Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.165
|
Mouse |
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.162
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.160
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.159
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.158
|
Mouse |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.158
|
|
|
|
positive regulation of phagocytosis engulfment
|
GO:0060100 |
3 |
0.158
|
|
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
18 |
0.158
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.157
|
|
|
|
face development
|
GO:0060324 |
38 |
0.157
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.156
|
|
|
|
memory
|
GO:0007613 |
58 |
0.156
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.156
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.156
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.155
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.155
|
Mouse |
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.153
|
|
|
|
regulation of bone remodeling
|
GO:0046850 |
28 |
0.153
|
|
|
|
response to inactivity
|
GO:0014854 |
4 |
0.152
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.152
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.150
|
|
|
|
positive regulation of tissue remodeling
|
GO:0034105 |
19 |
0.149
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.148
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.147
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.145
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.145
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.145
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.143
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.143
|
Mouse |
|
|
dendritic spine organization
|
GO:0097061 |
26 |
0.143
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.142
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.142
|
Fly |
|
|
odontogenesis
|
GO:0042476 |
78 |
0.141
|
|
|
|
embryonic placenta morphogenesis
|
GO:0060669 |
25 |
0.140
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.139
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.138
|
|
|
|
positive regulation of apoptotic cell clearance
|
GO:2000427 |
3 |
0.136
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.135
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.135
|
|
|
|
negative regulation of blood coagulation
|
GO:0030195 |
11 |
0.135
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.134
|
Mouse |
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.134
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.133
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.132
|
Fly |
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.132
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
24 |
0.131
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.131
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.131
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.131
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.130
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.130
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
33 |
0.130
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.129
|
|
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
32 |
0.129
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.128
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.127
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.126
|
Mouse |
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.126
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.124
|
|
|
|
metanephros development
|
GO:0001656 |
79 |
0.124
|
|
|
|
positive regulation of osteoblast proliferation
|
GO:0033690 |
9 |
0.124
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.123
|
Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.123
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.122
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.122
|
Fly |
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.122
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.122
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.121
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.120
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.118
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.117
|
Mouse |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.117
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
23 |
0.116
|
Mouse |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.114
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.114
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.112
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.111
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.111
|
|
|
|
chorio allantoic fusion
|
GO:0060710 |
8 |
0.111
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.110
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.109
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.109
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.108
|
Mouse Fly |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.107
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.105
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.105
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.103
|
Mouse |
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.102
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.102
|
Fly |
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.102
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.102
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.101
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.099
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.097
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.096
|
|
|
|
regulation of organ growth
|
GO:0046620 |
61 |
0.096
|
|
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.096
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.096
|
|
|
|
regulation of platelet activation
|
GO:0010543 |
17 |
0.095
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.095
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.095
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.094
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.094
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.094
|
Mouse Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.092
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.092
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.091
|
|
|
|
labyrinthine layer morphogenesis
|
GO:0060713 |
21 |
0.090
|
|
|
|
platelet aggregation
|
GO:0070527 |
20 |
0.089
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.089
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.088
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.088
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.087
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.087
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.086
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.086
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.086
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.085
|
|
|
|
regulation of muscle adaptation
|
GO:0043502 |
31 |
0.085
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.084
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
28 |
0.084
|
|
|
|
substrate dependent cell migration
|
GO:0006929 |
18 |
0.083
|
Fly |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.083
|
Worm |
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.083
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.083
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.082
|
Fly |
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.082
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.082
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.082
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.081
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.081
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.080
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.079
|
Fly |
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.079
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.079
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.077
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.077
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.076
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.076
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.076
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
3 |
0.075
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.075
|
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.074
|
|
|
|
regulation of adrenergic receptor signaling pathway
|
GO:0071877 |
4 |
0.074
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.074
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.073
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.073
|
Fly |
|
|
heart trabecula formation
|
GO:0060347 |
14 |
0.073
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.072
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.072
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.072
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.070
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.070
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.070
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.069
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
15 |
0.069
|
|
|
|
positive regulation of coagulation
|
GO:0050820 |
13 |
0.069
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.069
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.069
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.069
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.069
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.069
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.068
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.068
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.068
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.068
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
4 |
0.068
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.067
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.067
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.067
|
Fly |
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.067
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.067
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.067
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.067
|
Fly |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.066
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.066
|
Mouse |
|
|
regulation of osteoblast proliferation
|
GO:0033688 |
15 |
0.065
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.065
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.064
|
|
|
|
killing by host of symbiont cells
|
GO:0051873 |
11 |
0.064
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
44 |
0.064
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.064
|
|
|
|
negative regulation of alcohol biosynthetic process
|
GO:1902931 |
4 |
0.064
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.064
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
33 |
0.064
|
|
|
|
regulation of phagocytosis engulfment
|
GO:0060099 |
5 |
0.064
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
45 |
0.064
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.063
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.063
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.063
|
|
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
13 |
0.062
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.062
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.062
|
|
|
|
positive regulation of blood coagulation
|
GO:0030194 |
10 |
0.062
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.062
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.061
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.061
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.061
|
|
|
|
regulation of renal output by angiotensin
|
GO:0002019 |
2 |
0.061
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
27 |
0.060
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.060
|
|
|
|
cell cell adhesion mediated by integrin
|
GO:0033631 |
6 |
0.060
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.060
|
Fly |
|
|
circulatory system process
|
GO:0003013 |
197 |
0.060
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.060
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.059
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.059
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.059
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.059
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
26 |
0.059
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
55 |
0.059
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.059
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.059
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.058
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.058
|
|
|
|
positive regulation of insulin receptor signaling pathway
|
GO:0046628 |
4 |
0.058
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.057
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.057
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.057
|
Fly |
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.057
|
Mouse |
|
|
cognition
|
GO:0050890 |
149 |
0.056
|
Mouse |
|
|
lipid localization
|
GO:0010876 |
126 |
0.056
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.056
|
|
|
|
neutrophil mediated killing of gram positive bacterium
|
GO:0070946 |
2 |
0.056
|
|
|
|
negative regulation of epidermal growth factor receptor signaling pathway
|
GO:0042059 |
6 |
0.056
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.056
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.056
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.055
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.055
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.055
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
27 |
0.054
|
Fly |
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.054
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.054
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.054
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.054
|
Mouse |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.054
|
|
|
|
collagen biosynthetic process
|
GO:0032964 |
7 |
0.054
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
28 |
0.053
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.053
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.053
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.053
|
|
|
|
positive regulation of regulated secretory pathway
|
GO:1903307 |
10 |
0.053
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.053
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.052
|
Fly |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
35 |
0.052
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.052
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.052
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.052
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.052
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.052
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.051
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.051
|
Worm |
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.051
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.051
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.051
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.051
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.051
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.050
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.050
|
|
|
|
regulation of heart growth
|
GO:0060420 |
31 |
0.050
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.050
|
|
|
|
glycosaminoglycan biosynthetic process
|
GO:0006024 |
15 |
0.050
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.050
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.049
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.049
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.049
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.049
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.049
|
|
|
|
protein citrullination
|
GO:0018101 |
2 |
0.048
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.048
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.048
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.048
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.048
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.048
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.048
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.048
|
|
