Mus musculus

98 known processes

Ofd1

oral-facial-digital syndrome 1 gene homolog (human)

(Aliases: ORF2,DXGgc7e,Cxorf5)

Ofd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic cyclic compound catabolic process GO:1901361 295 0.068
cilium morphogenesis GO:0060271 102 0.066
purine nucleotide metabolic process GO:0006163 302 0.061
purine nucleoside triphosphate metabolic process GO:0009144 226 0.051
nucleoside catabolic process GO:0009164 206 0.047
cellular nitrogen compound catabolic process GO:0044270 280 0.045
purine containing compound metabolic process GO:0072521 311 0.045
purine nucleoside catabolic process GO:0006152 205 0.044
nucleoside phosphate catabolic process GO:1901292 222 0.042
microtubule based transport GO:0010970 50 0.042
microtubule based movement GO:0007018 84 0.041
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.041
nucleoside triphosphate metabolic process GO:0009141 230 0.040
cellular amino acid metabolic process GO:0006520 103 0.040
stem cell differentiation GO:0048863 268 0.040
stem cell maintenance GO:0019827 130 0.037
apoptotic signaling pathway GO:0097190 306 0.036
myosin filament organization GO:0031033 3 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
regulation of cellular ketone metabolic process GO:0010565 66 0.036
purine ribonucleoside metabolic process GO:0046128 241 0.035
small gtpase mediated signal transduction GO:0007264 97 0.035
cellular ketone metabolic process GO:0042180 84 0.035
nucleoside metabolic process GO:0009116 246 0.035
ribonucleoside catabolic process GO:0042454 206 0.034
heterocycle catabolic process GO:0046700 280 0.033
purine ribonucleotide catabolic process GO:0009154 208 0.033
peptidyl amino acid modification GO:0018193 336 0.033
transmission of nerve impulse GO:0019226 76 0.032
organonitrogen compound catabolic process GO:1901565 264 0.032
cytoskeleton dependent intracellular transport GO:0030705 50 0.032
glycosyl compound catabolic process GO:1901658 206 0.032
organophosphate catabolic process GO:0046434 232 0.031
purine ribonucleotide metabolic process GO:0009150 290 0.031
neuronal action potential GO:0019228 54 0.031
macromolecule catabolic process GO:0009057 281 0.031
nucleoside phosphate metabolic process GO:0006753 338 0.031
purine nucleoside metabolic process GO:0042278 241 0.030
regulation of cellular amine metabolic process GO:0033238 20 0.030
purine containing compound catabolic process GO:0072523 213 0.030
ribonucleoside triphosphate metabolic process GO:0009199 220 0.030
purine nucleoside triphosphate catabolic process GO:0009146 203 0.030
cellular amine metabolic process GO:0044106 44 0.029
purine ribonucleoside catabolic process GO:0046130 205 0.029
stem cell development GO:0048864 219 0.028
ribonucleotide catabolic process GO:0009261 208 0.028
aromatic compound catabolic process GO:0019439 286 0.028
ribonucleotide metabolic process GO:0009259 291 0.028
regulation of dna damage checkpoint GO:2000001 3 0.028
positive regulation of protein modification process GO:0031401 299 0.027
ribonucleoside triphosphate catabolic process GO:0009203 199 0.027
camera type eye development GO:0043010 266 0.027
nucleotide catabolic process GO:0009166 217 0.027
cellular macromolecule catabolic process GO:0044265 206 0.027
nucleotide metabolic process GO:0009117 332 0.027
myosin filament assembly GO:0031034 2 0.027
nucleoside triphosphate catabolic process GO:0009143 205 0.026
regulation of cellular response to stress GO:0080135 159 0.026
establishment or maintenance of cell polarity GO:0007163 86 0.026
purine nucleotide catabolic process GO:0006195 211 0.026
negative regulation of cell proliferation GO:0008285 296 0.026
ras protein signal transduction GO:0007265 77 0.025
microtubule based process GO:0007017 236 0.025
ribonucleoside metabolic process GO:0009119 245 0.025
action potential GO:0001508 78 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
regulation of nucleotide metabolic process GO:0006140 169 0.024
amine metabolic process GO:0009308 45 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
intraciliary transport GO:0042073 9 0.023
mrna metabolic process GO:0016071 84 0.023
organelle assembly GO:0070925 177 0.023
negative regulation of molecular function GO:0044092 258 0.023
actin cytoskeleton organization GO:0030036 220 0.022
maintenance of location GO:0051235 89 0.022
positive regulation of glial cell proliferation GO:0060252 4 0.022
nucleobase containing small molecule metabolic process GO:0055086 352 0.022
dna repair GO:0006281 107 0.022
g protein coupled receptor signaling pathway GO:0007186 243 0.022
cellular response to dna damage stimulus GO:0006974 207 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
respiratory system development GO:0060541 190 0.021
immune effector process GO:0002252 321 0.021
cation transport GO:0006812 399 0.020
eye photoreceptor cell development GO:0042462 31 0.020
positive regulation of nervous system development GO:0051962 221 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
regulation of hydrolase activity GO:0051336 246 0.020
nuclear division GO:0000280 158 0.019
sensory organ morphogenesis GO:0090596 242 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.019
leukocyte mediated immunity GO:0002443 174 0.019
regulation of cell cycle checkpoint GO:1901976 9 0.018
lymphocyte activation involved in immune response GO:0002285 93 0.018
lipid localization GO:0010876 126 0.018
multicellular organismal signaling GO:0035637 91 0.018
cation transmembrane transport GO:0098655 266 0.018
photoreceptor cell development GO:0042461 40 0.018
eye photoreceptor cell differentiation GO:0001754 41 0.018
transmembrane transport GO:0055085 412 0.018
mitotic cell cycle GO:0000278 195 0.017
regulation of mapk cascade GO:0043408 248 0.017
regulation of cell cycle GO:0051726 281 0.017
regulation of binding GO:0051098 111 0.017
organelle fission GO:0048285 170 0.017
organelle localization GO:0051640 179 0.017
response to growth factor GO:0070848 198 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
chemotaxis GO:0006935 247 0.016
gtp catabolic process GO:0006184 143 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
positive regulation of kinase activity GO:0033674 155 0.016
regulation of kinase activity GO:0043549 249 0.016
cellular protein catabolic process GO:0044257 155 0.016
axonogenesis GO:0007409 274 0.015
cell type specific apoptotic process GO:0097285 268 0.015
purine nucleoside monophosphate catabolic process GO:0009128 58 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
regulation of membrane potential GO:0042391 192 0.015
cellular response to lipid GO:0071396 145 0.015
myelination GO:0042552 74 0.015
regulation of transferase activity GO:0051338 263 0.014
muscle adaptation GO:0043500 39 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
muscle cell differentiation GO:0042692 261 0.014
ion transmembrane transport GO:0034220 361 0.014
regulation of organelle organization GO:0033043 289 0.014
positive regulation of transferase activity GO:0051347 167 0.014
axon ensheathment GO:0008366 76 0.014
digestive system development GO:0055123 200 0.014
Zebrafish
small molecule biosynthetic process GO:0044283 132 0.014
intracellular protein transport GO:0006886 204 0.014
nitrogen compound transport GO:0071705 271 0.014
placenta development GO:0001890 140 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
blood vessel morphogenesis GO:0048514 285 0.014
cellular response to external stimulus GO:0071496 88 0.013
ensheathment of neurons GO:0007272 76 0.013
tube closure GO:0060606 91 0.013
regulation of cell motility GO:2000145 236 0.013
ear development GO:0043583 200 0.013
regulation of neuron differentiation GO:0045664 281 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
chromatin modification GO:0016568 187 0.013
female meiosis chromosome segregation GO:0016321 1 0.013
regulation of cell activation GO:0050865 289 0.013
microtubule anchoring at microtubule organizing center GO:0072393 5 0.013
lymphocyte differentiation GO:0030098 242 0.013
kidney development GO:0001822 213 0.013
epithelial cell proliferation GO:0050673 174 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
male gamete generation GO:0048232 285 0.013
cytoplasmic transport GO:0016482 234 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
adaptive immune response GO:0002250 155 0.013
regulation of cell cycle process GO:0010564 160 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
t cell activation GO:0042110 289 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
regulation of response to dna damage stimulus GO:2001020 34 0.012
regulation of cell adhesion GO:0030155 154 0.012
striated muscle cell development GO:0055002 125 0.012
striated muscle myosin thick filament assembly GO:0071688 1 0.012
b cell activation GO:0042113 161 0.012
spermatogenesis GO:0007283 284 0.012
protein maturation GO:0051604 176 0.012
compound eye development GO:0048749 1 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
negative regulation of cell development GO:0010721 169 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.012
retina development in camera type eye GO:0060041 119 0.012
rna processing GO:0006396 105 0.012
regulation of neuron projection development GO:0010975 169 0.012
cell adhesion GO:0007155 329 0.011
protein targeting GO:0006605 143 0.011
regulation of secretion by cell GO:1903530 249 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
positive regulation of gtp catabolic process GO:0033126 85 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
cell fate commitment GO:0045165 210 0.011
regulation of transmembrane transport GO:0034762 128 0.011
muscle cell development GO:0055001 133 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
regulation of protein localization GO:0032880 231 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
digestive tract development GO:0048565 190 0.011
Zebrafish
posttranscriptional regulation of gene expression GO:0010608 155 0.011
regulation of hormone levels GO:0010817 211 0.011
regulation of cell migration GO:0030334 219 0.011
gland development GO:0048732 330 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
protein localization to organelle GO:0033365 185 0.011
chromatin organization GO:0006325 206 0.011
heart morphogenesis GO:0003007 178 0.011
atp metabolic process GO:0046034 75 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
establishment of vesicle localization GO:0051650 81 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
guanosine containing compound metabolic process GO:1901068 144 0.010
positive regulation of cell development GO:0010720 237 0.010
b cell mediated immunity GO:0019724 71 0.010
meiotic nuclear division GO:0007126 115 0.010
methylation GO:0032259 134 0.010
cell activation involved in immune response GO:0002263 126 0.010
organic acid biosynthetic process GO:0016053 86 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
microtubule cytoskeleton organization GO:0000226 157 0.010
neuron apoptotic process GO:0051402 142 0.010
regulation of neuron death GO:1901214 134 0.010
regulation of epithelial cell proliferation GO:0050678 141 0.010
positive regulation of apoptotic process GO:0043065 217 0.010
sterol transport GO:0015918 38 0.010
organic hydroxy compound transport GO:0015850 93 0.010
regulation of t cell activation GO:0050863 170 0.010
lipid transport GO:0006869 98 0.010
response to organic cyclic compound GO:0014070 198 0.010
negative regulation of phosphorus metabolic process GO:0010563 184 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010

Ofd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.046
eye and adnexa disease DOID:1492 0 0.046
disease of anatomical entity DOID:7 0 0.046
sensory system disease DOID:0050155 0 0.046
eye disease DOID:5614 0 0.029
musculoskeletal system disease DOID:17 0 0.025
retinal disease DOID:5679 0 0.019
retinal degeneration DOID:8466 0 0.018
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.015
organ system cancer DOID:0050686 0 0.015
retinitis pigmentosa DOID:10584 0 0.013