Mus musculus

107 known processes

Sohlh2

spermatogenesis and oogenesis specific basic helix-loop-helix 2

(Aliases: 4933406N12Rik,AI413378)

Sohlh2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatogenesis GO:0007283 284 0.209
Mouse
male gamete generation GO:0048232 285 0.186
Mouse
germ cell development GO:0007281 185 0.124
ion transmembrane transport GO:0034220 361 0.118
dna methylation involved in gamete generation GO:0043046 15 0.113
microtubule cytoskeleton organization GO:0000226 157 0.088
transmembrane transport GO:0055085 412 0.088
lipid biosynthetic process GO:0008610 179 0.080
male meiosis GO:0007140 37 0.078
inorganic ion transmembrane transport GO:0098660 234 0.077
cation transmembrane transport GO:0098655 266 0.072
gonad development GO:0008406 141 0.070
nucleobase containing small molecule metabolic process GO:0055086 352 0.069
ribonucleotide metabolic process GO:0009259 291 0.064
cation transport GO:0006812 399 0.064
purine containing compound metabolic process GO:0072521 311 0.064
reactive oxygen species metabolic process GO:0072593 84 0.063
nucleoside phosphate metabolic process GO:0006753 338 0.063
ribose phosphate metabolic process GO:0019693 291 0.062
inorganic cation transmembrane transport GO:0098662 207 0.058
spermatid differentiation GO:0048515 115 0.055
spermatid development GO:0007286 108 0.055
ovulation cycle GO:0042698 59 0.054
meiosis i GO:0007127 60 0.054
oxidation reduction process GO:0055114 342 0.053
dna metabolic process GO:0006259 303 0.052
cellular amino acid metabolic process GO:0006520 103 0.051
cellular protein catabolic process GO:0044257 155 0.050
cellular lipid metabolic process GO:0044255 323 0.049
response to organonitrogen compound GO:0010243 246 0.048
regulation of cellular ketone metabolic process GO:0010565 66 0.048
purine ribonucleotide metabolic process GO:0009150 290 0.048
organonitrogen compound biosynthetic process GO:1901566 192 0.047
methylation GO:0032259 134 0.046
regulation of cellular catabolic process GO:0031329 242 0.046
development of primary sexual characteristics GO:0045137 143 0.045
fertilization GO:0009566 127 0.045
ovarian follicle development GO:0001541 40 0.044
cellular macromolecule catabolic process GO:0044265 206 0.044
development of primary female sexual characteristics GO:0046545 73 0.043
neural precursor cell proliferation GO:0061351 121 0.042
oogenesis GO:0048477 56 0.042
nucleotide metabolic process GO:0009117 332 0.041
oocyte differentiation GO:0009994 35 0.041
calcium ion transmembrane transport GO:0070588 85 0.039
meiotic nuclear division GO:0007126 115 0.039
organelle fission GO:0048285 170 0.039
meiotic cell cycle GO:0051321 122 0.039
macromolecule catabolic process GO:0009057 281 0.039
organophosphate biosynthetic process GO:0090407 122 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.039
regulation of reactive oxygen species metabolic process GO:2000377 40 0.039
male meiosis i GO:0007141 16 0.038
multicellular organism growth GO:0035264 161 0.038
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.038
macromolecule methylation GO:0043414 120 0.038
microtubule based process GO:0007017 236 0.037
cellular response to growth factor stimulus GO:0071363 197 0.037
amine metabolic process GO:0009308 45 0.036
synapsis GO:0007129 34 0.036
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.035
chromatin organization GO:0006325 206 0.035
cellular response to hormone stimulus GO:0032870 150 0.034
positive regulation of cell death GO:0010942 224 0.034
nucleoside phosphate biosynthetic process GO:1901293 79 0.033
regulation of multi organism process GO:0043900 111 0.032
cellular amine metabolic process GO:0044106 44 0.032
regulation of feeding behavior GO:0060259 3 0.032
regulation of organelle organization GO:0033043 289 0.032
camera type eye development GO:0043010 266 0.032
protein methylation GO:0006479 81 0.031
carbohydrate derivative biosynthetic process GO:1901137 183 0.031
regulation of transmembrane transport GO:0034762 128 0.031
apoptotic signaling pathway GO:0097190 306 0.031
female gonad development GO:0008585 71 0.030
regulation of system process GO:0044057 200 0.030
cellular ketone metabolic process GO:0042180 84 0.029
homeostasis of number of cells GO:0048872 210 0.029
multicellular organismal homeostasis GO:0048871 164 0.029
regulation of cellular amino acid metabolic process GO:0006521 5 0.029
myeloid cell differentiation GO:0030099 233 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
regulation of establishment of protein localization GO:0070201 181 0.027
locomotory behavior GO:0007626 195 0.027
chromosome organization involved in meiosis GO:0070192 39 0.027
female sex differentiation GO:0046660 84 0.026
regulation of secretion GO:0051046 274 0.026
positive regulation of protein modification process GO:0031401 299 0.026
carbohydrate biosynthetic process GO:0016051 74 0.026
skeletal system development GO:0001501 356 0.026
regulation of secretion by cell GO:1903530 249 0.025
pirna metabolic process GO:0034587 12 0.025
positive regulation of programmed cell death GO:0043068 218 0.025
chromatin modification GO:0016568 187 0.025
nuclear division GO:0000280 158 0.025
neuron apoptotic process GO:0051402 142 0.025
rhythmic process GO:0048511 174 0.025
pole plasm assembly GO:0007315 2 0.025
cell fate commitment GO:0045165 210 0.025
stem cell differentiation GO:0048863 268 0.024
regulation of ion transmembrane transport GO:0034765 119 0.024
response to organic cyclic compound GO:0014070 198 0.024
regulation of neuron death GO:1901214 134 0.024
histone modification GO:0016570 159 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.024
regulation of reproductive process GO:2000241 66 0.023
regulation of neural precursor cell proliferation GO:2000177 70 0.023
tissue homeostasis GO:0001894 115 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
lung development GO:0030324 164 0.022
response to peptide hormone GO:0043434 127 0.022
protein localization to organelle GO:0033365 185 0.022
anatomical structure homeostasis GO:0060249 145 0.022
respiratory system development GO:0060541 190 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.021
regionalization GO:0003002 337 0.021
cartilage development GO:0051216 140 0.021
regulation of neuron apoptotic process GO:0043523 122 0.021
developmental maturation GO:0021700 193 0.021
glycerolipid metabolic process GO:0046486 122 0.021
positive regulation of apoptotic process GO:0043065 217 0.021
purine nucleotide biosynthetic process GO:0006164 65 0.020
translation GO:0006412 93 0.020
male sex differentiation GO:0046661 109 0.020
regulation of chromosome organization GO:0033044 83 0.020
nucleoside metabolic process GO:0009116 246 0.020
reactive nitrogen species metabolic process GO:2001057 0 0.020
regulation of voltage gated calcium channel activity GO:1901385 4 0.019
glucose homeostasis GO:0042593 128 0.019
nucleotide biosynthetic process GO:0009165 78 0.019
regulation of wnt signaling pathway GO:0030111 123 0.019
regulation of homeostatic process GO:0032844 182 0.019
oocyte construction GO:0007308 2 0.019
carbohydrate metabolic process GO:0005975 230 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
regulation of translation GO:0006417 71 0.019
regulation of cell cycle process GO:0010564 160 0.019
regulation of protein localization GO:0032880 231 0.018
response to peptide GO:1901652 136 0.018
canonical wnt signaling pathway GO:0060070 130 0.018
organic anion transport GO:0015711 137 0.018
regulation of ion transport GO:0043269 215 0.018
regulation of cell cycle GO:0051726 281 0.018
ribose phosphate biosynthetic process GO:0046390 59 0.018
purine containing compound biosynthetic process GO:0072522 70 0.018
blood vessel morphogenesis GO:0048514 285 0.018
mitotic cell cycle process GO:1903047 159 0.018
cell growth GO:0016049 130 0.018
reactive oxygen species biosynthetic process GO:1903409 8 0.018
regulation of defense response GO:0031347 233 0.018
ribonucleotide biosynthetic process GO:0009260 59 0.018
potassium ion homeostasis GO:0055075 4 0.018
negative regulation of cell cycle GO:0045786 123 0.017
cell maturation GO:0048469 127 0.017
mitotic cell cycle GO:0000278 195 0.017
meiotic cell cycle process GO:1903046 77 0.017
regulation of cytokine production GO:0001817 266 0.017
energy derivation by oxidation of organic compounds GO:0015980 77 0.017
adult behavior GO:0030534 135 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
maintenance of location GO:0051235 89 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
g protein coupled receptor signaling pathway GO:0007186 243 0.017
cyclic nucleotide metabolic process GO:0009187 59 0.017
stem cell maintenance GO:0019827 130 0.017
cellular response to peptide hormone stimulus GO:0071375 92 0.017
cellular response to cytokine stimulus GO:0071345 189 0.017
triglyceride metabolic process GO:0006641 51 0.017
stem cell development GO:0048864 219 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
protein catabolic process GO:0030163 221 0.017
carbohydrate homeostasis GO:0033500 128 0.017
respiratory tube development GO:0030323 167 0.017
amino acid transmembrane transport GO:0003333 37 0.017
sperm motility GO:0030317 47 0.017
neuron death GO:0070997 154 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
gland development GO:0048732 330 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
epithelial cell development GO:0002064 159 0.016
extracellular matrix organization GO:0030198 147 0.016
synaptic transmission GO:0007268 329 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.016
connective tissue development GO:0061448 179 0.016
negative regulation of organelle organization GO:0010639 90 0.016
regulation of protein serine threonine kinase activity GO:0071900 157 0.016
regulation of hydrolase activity GO:0051336 246 0.016
anion transport GO:0006820 177 0.016
cellular homeostasis GO:0019725 240 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
amino acid transport GO:0006865 61 0.016
oocyte development GO:0048599 33 0.016
multi multicellular organism process GO:0044706 109 0.016
lipid localization GO:0010876 126 0.015
regulation of carbohydrate biosynthetic process GO:0043255 40 0.015
protein localization to nucleus GO:0034504 121 0.015
regulation of hormone levels GO:0010817 211 0.015
urogenital system development GO:0001655 261 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
retina development in camera type eye GO:0060041 119 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
anion transmembrane transport GO:0098656 71 0.015
regulation of cell growth GO:0001558 91 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.015
regulation of intracellular transport GO:0032386 159 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
oocyte anterior posterior axis specification GO:0007314 2 0.015
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.015
protein ubiquitination GO:0016567 171 0.015
protein import into nucleus GO:0006606 95 0.015
nucleoside catabolic process GO:0009164 206 0.015
immune effector process GO:0002252 321 0.015
blastocyst development GO:0001824 80 0.015
nitrogen compound transport GO:0071705 271 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
muscle tissue development GO:0060537 308 0.015
divalent inorganic cation transport GO:0072511 178 0.015
cellular response to insulin stimulus GO:0032869 78 0.015
generation of precursor metabolites and energy GO:0006091 103 0.014
skeletal system morphogenesis GO:0048705 203 0.014
intracellular mrna localization GO:0008298 4 0.014
purine containing compound catabolic process GO:0072523 213 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
regulation of inositol phosphate biosynthetic process GO:0010919 3 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
epithelial tube morphogenesis GO:0060562 303 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
dna modification GO:0006304 50 0.014
divalent metal ion transport GO:0070838 172 0.014
dna conformation change GO:0071103 37 0.014
sensory perception of sound GO:0007605 97 0.014
purine ribonucleotide biosynthetic process GO:0009152 59 0.014
cell type specific apoptotic process GO:0097285 268 0.014
response to extracellular stimulus GO:0009991 127 0.014
nucleoside monophosphate metabolic process GO:0009123 85 0.014
fat cell differentiation GO:0045444 160 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
sulfur compound metabolic process GO:0006790 100 0.014
oocyte axis specification GO:0007309 2 0.014
regulation of lipid biosynthetic process GO:0046890 54 0.014
intracellular protein transport GO:0006886 204 0.014
asymmetric stem cell division GO:0098722 3 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
asymmetric neuroblast division GO:0055059 1 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
wnt signaling pathway GO:0016055 188 0.013
response to acid chemical GO:0001101 111 0.013
regulation of proteolysis GO:0030162 164 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
female gamete generation GO:0007292 74 0.013
dna methylation GO:0006306 43 0.013
cell proliferation in hindbrain GO:0021534 10 0.013
positive regulation of cellular amine metabolic process GO:0033240 5 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
regulation of protein catabolic process GO:0042176 108 0.013
positive regulation of nervous system development GO:0051962 221 0.013
nucleus organization GO:0006997 45 0.012
gene silencing by rna GO:0031047 19 0.012
negative regulation of molecular function GO:0044092 258 0.012
regulation of response to wounding GO:1903034 189 0.012
establishment or maintenance of cell polarity GO:0007163 86 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
nuclear transport GO:0051169 139 0.012
positive regulation of camp mediated signaling GO:0043950 3 0.012
protein kinase b signaling GO:0043491 74 0.012
single organism cell adhesion GO:0098602 156 0.012
maternal determination of anterior posterior axis embryo GO:0008358 2 0.012
protein alkylation GO:0008213 81 0.012
cellular protein complex assembly GO:0043623 116 0.012
monovalent inorganic cation homeostasis GO:0055067 33 0.012
cell division GO:0051301 120 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
sensory perception GO:0007600 245 0.012
cognition GO:0050890 149 0.012
negative regulation of fat cell differentiation GO:0045599 36 0.012
insulin secretion GO:0030073 89 0.012
aromatic compound catabolic process GO:0019439 286 0.012
epithelial tube formation GO:0072175 130 0.012
adult locomotory behavior GO:0008344 91 0.012
cytoplasmic transport GO:0016482 234 0.012
cell differentiation in spinal cord GO:0021515 53 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
cellular chemical homeostasis GO:0055082 215 0.012
metal ion homeostasis GO:0055065 189 0.011
male genitalia morphogenesis GO:0048808 4 0.011
cellular response to inorganic substance GO:0071241 37 0.011
kidney development GO:0001822 213 0.011
membrane organization GO:0061024 245 0.011
actin cytoskeleton organization GO:0030036 220 0.011
steroid metabolic process GO:0008202 119 0.011
regulation of angiogenesis GO:0045765 81 0.011
rna interference GO:0016246 2 0.011
response to growth factor GO:0070848 198 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
covalent chromatin modification GO:0016569 163 0.011
ventral spinal cord interneuron differentiation GO:0021514 16 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
regulation of anatomical structure size GO:0090066 178 0.011
response to light stimulus GO:0009416 135 0.011
protein secretion GO:0009306 111 0.011
angiogenesis GO:0001525 201 0.011
protein processing GO:0016485 163 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
cellularization GO:0007349 1 0.011
striated muscle tissue development GO:0014706 293 0.011
bmp signaling pathway GO:0030509 93 0.011
male anatomical structure morphogenesis GO:0090598 4 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.011
organic cyclic compound catabolic process GO:1901361 295 0.011
histone methylation GO:0016571 71 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
regulation of cellular response to growth factor stimulus GO:0090287 82 0.011
regulation of inositol trisphosphate biosynthetic process GO:0032960 3 0.011
negative regulation of protein metabolic process GO:0051248 282 0.011
regulation of interferon gamma production GO:0032649 57 0.011
camp metabolic process GO:0046058 40 0.011
hexose metabolic process GO:0019318 98 0.011
dephosphorylation GO:0016311 129 0.011
rna processing GO:0006396 105 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
regulation of canonical wnt signaling pathway GO:0060828 82 0.011
forebrain development GO:0030900 302 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
dendrite development GO:0016358 115 0.010
male gonad development GO:0008584 88 0.010
heterocycle catabolic process GO:0046700 280 0.010
response to insulin GO:0032868 100 0.010
cell proliferation in external granule layer GO:0021924 10 0.010
hormone metabolic process GO:0042445 86 0.010
cellular response to organic cyclic compound GO:0071407 87 0.010
regulation of ossification GO:0030278 112 0.010
negative regulation of cell size GO:0045792 3 0.010
exocytosis GO:0006887 121 0.010
negative regulation of cell development GO:0010721 169 0.010
sodium ion transmembrane transport GO:0035725 49 0.010
macromolecular complex disassembly GO:0032984 43 0.010
regulation of cell migration GO:0030334 219 0.010
regulation of apoptotic signaling pathway GO:2001233 197 0.010
attachment of spindle microtubules to kinetochore GO:0008608 4 0.010
organelle localization GO:0051640 179 0.010
leukocyte differentiation GO:0002521 342 0.010
regulation of membrane potential GO:0042391 192 0.010
protein import GO:0017038 101 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
spinal cord dorsal ventral patterning GO:0021513 23 0.010
alcohol metabolic process GO:0006066 116 0.010
regulation of protein transport GO:0051223 163 0.010
regulation of protein kinase activity GO:0045859 232 0.010
morphogenesis of a branching epithelium GO:0061138 193 0.010

Sohlh2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.019
disease of metabolism DOID:0014667 0 0.015