Mus musculus

146 known processes

Wdpcp

WD repeat containing planar cell polarity effector

(Aliases: AV249152)

Wdpcp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium assembly GO:0042384 81 0.814
regulation of cilium assembly GO:1902017 7 0.689
cilium morphogenesis GO:0060271 102 0.251
cellular component assembly involved in morphogenesis GO:0010927 139 0.199
organelle assembly GO:0070925 177 0.180
nonmotile primary cilium assembly GO:0035058 8 0.111
smoothened signaling pathway GO:0007224 105 0.083
intraciliary retrograde transport GO:0035721 3 0.056
positive regulation of organelle organization GO:0010638 128 0.048
negative regulation of cell proliferation GO:0008285 296 0.047
regulation of organelle organization GO:0033043 289 0.046
skeletal system development GO:0001501 356 0.046
establishment of tissue polarity GO:0007164 28 0.046
cellular amino acid metabolic process GO:0006520 103 0.044
regulation of cellular component biogenesis GO:0044087 181 0.042
cellular lipid metabolic process GO:0044255 323 0.041
epidermis development GO:0008544 187 0.040
canonical wnt signaling pathway GO:0060070 130 0.039
cellular ketone metabolic process GO:0042180 84 0.039
amine metabolic process GO:0009308 45 0.038
transmembrane transport GO:0055085 412 0.036
protein processing GO:0016485 163 0.035
tube formation GO:0035148 140 0.035
skin development GO:0043588 220 0.034
regulation of cellular response to growth factor stimulus GO:0090287 82 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.033
cytoskeleton dependent intracellular transport GO:0030705 50 0.032
organonitrogen compound catabolic process GO:1901565 264 0.031
regulation of cell projection organization GO:0031344 206 0.031
aromatic compound catabolic process GO:0019439 286 0.031
nucleotide metabolic process GO:0009117 332 0.031
cation transport GO:0006812 399 0.031
regulation of stem cell differentiation GO:2000736 50 0.030
organic cyclic compound catabolic process GO:1901361 295 0.029
cellular amine metabolic process GO:0044106 44 0.029
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.029
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.029
spermatogenesis GO:0007283 284 0.028
wnt signaling pathway GO:0016055 188 0.028
positive regulation of cellular component biogenesis GO:0044089 94 0.028
regulation of cellular ketone metabolic process GO:0010565 66 0.028
negative regulation of epithelial to mesenchymal transition GO:0010719 6 0.028
regulation of wnt signaling pathway GO:0030111 123 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.027
purine containing compound metabolic process GO:0072521 311 0.027
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
regulation of smoothened signaling pathway GO:0008589 58 0.026
ribonucleotide metabolic process GO:0009259 291 0.025
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.025
protein maturation GO:0051604 176 0.025
epithelial tube formation GO:0072175 130 0.025
cellular response to growth factor stimulus GO:0071363 197 0.025
negative regulation of cellular component organization GO:0051129 194 0.025
purine nucleotide metabolic process GO:0006163 302 0.025
regulation of hormone levels GO:0010817 211 0.024
microtubule based process GO:0007017 236 0.024
regulation of cellular amine metabolic process GO:0033238 20 0.024
cation transmembrane transport GO:0098655 266 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
negative regulation of cell development GO:0010721 169 0.024
heterocycle catabolic process GO:0046700 280 0.024
glycosyl compound metabolic process GO:1901657 246 0.024
nucleoside metabolic process GO:0009116 246 0.024
neural tube development GO:0021915 160 0.024
purine nucleotide catabolic process GO:0006195 211 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
purine ribonucleotide metabolic process GO:0009150 290 0.023
response to growth factor GO:0070848 198 0.023
ion transmembrane transport GO:0034220 361 0.023
locomotory behavior GO:0007626 195 0.023
epithelial tube morphogenesis GO:0060562 303 0.022
regulation of homeostatic process GO:0032844 182 0.022
nitrogen compound transport GO:0071705 271 0.022
apoptotic signaling pathway GO:0097190 306 0.022
regulation of cellular amino acid metabolic process GO:0006521 5 0.022
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.022
embryonic organ morphogenesis GO:0048562 276 0.022
cellular nitrogen compound catabolic process GO:0044270 280 0.021
cellular homeostasis GO:0019725 240 0.021
ribose phosphate metabolic process GO:0019693 291 0.020
macromolecule catabolic process GO:0009057 281 0.020
divalent inorganic cation transport GO:0072511 178 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
transmission of nerve impulse GO:0019226 76 0.020
ras protein signal transduction GO:0007265 77 0.020
reactive oxygen species metabolic process GO:0072593 84 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
purine nucleoside metabolic process GO:0042278 241 0.020
regulation of transferase activity GO:0051338 263 0.020
intraciliary transport GO:0042073 9 0.020
response to organonitrogen compound GO:0010243 246 0.020
microtubule based transport GO:0010970 50 0.020
lipid biosynthetic process GO:0008610 179 0.019
regulation of secretion GO:0051046 274 0.019
regulation of hydrolase activity GO:0051336 246 0.019
immune effector process GO:0002252 321 0.019
regulation of cell activation GO:0050865 289 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
sensory perception GO:0007600 245 0.019
spermatid differentiation GO:0048515 115 0.019
maintenance of location GO:0051235 89 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
dephosphorylation GO:0016311 129 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
carbohydrate homeostasis GO:0033500 128 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
cellular chemical homeostasis GO:0055082 215 0.018
regulation of secretion by cell GO:1903530 249 0.018
cytoplasmic transport GO:0016482 234 0.018
carbohydrate metabolic process GO:0005975 230 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
kidney development GO:0001822 213 0.018
embryonic epithelial tube formation GO:0001838 130 0.018
membrane organization GO:0061024 245 0.017
purine containing compound catabolic process GO:0072523 213 0.017
sensory organ morphogenesis GO:0090596 242 0.017
neural tube formation GO:0001841 108 0.017
germ cell development GO:0007281 185 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
rac protein signal transduction GO:0016601 13 0.016
establishment of planar polarity GO:0001736 28 0.016
morphogenesis of embryonic epithelium GO:0016331 159 0.016
t cell activation GO:0042110 289 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
response to lipopolysaccharide GO:0032496 128 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
regulation of cell projection assembly GO:0060491 38 0.016
male gamete generation GO:0048232 285 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
nucleoside catabolic process GO:0009164 206 0.016
tube closure GO:0060606 91 0.016
stem cell development GO:0048864 219 0.016
microtubule based movement GO:0007018 84 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
glycoprotein metabolic process GO:0009100 116 0.015
regulation of membrane potential GO:0042391 192 0.015
regulation of organelle assembly GO:1902115 19 0.015
lymphocyte proliferation GO:0046651 164 0.015
protein localization to organelle GO:0033365 185 0.015
hexose metabolic process GO:0019318 98 0.015
fat cell differentiation GO:0045444 160 0.015
protein catabolic process GO:0030163 221 0.015
respiratory system development GO:0060541 190 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
primary neural tube formation GO:0014020 95 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
purine ribonucleotide catabolic process GO:0009154 208 0.015
amide transport GO:0042886 138 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
compound eye development GO:0048749 1 0.015
reactive nitrogen species metabolic process GO:2001057 0 0.015
circulatory system process GO:0003013 197 0.015
regulation of canonical wnt signaling pathway GO:0060828 82 0.015
nucleotide catabolic process GO:0009166 217 0.015
synaptic transmission GO:0007268 329 0.014
spermatid development GO:0007286 108 0.014
regulation of cell motility GO:2000145 236 0.014
cellular ion homeostasis GO:0006873 165 0.014
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
rho protein signal transduction GO:0007266 32 0.014
response to insulin GO:0032868 100 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
organophosphate catabolic process GO:0046434 232 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
adult behavior GO:0030534 135 0.014
gtp catabolic process GO:0006184 143 0.014
spinal cord development GO:0021510 81 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
oxidation reduction process GO:0055114 342 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
ossification GO:0001503 216 0.014
positive regulation of cell death GO:0010942 224 0.014
limb development GO:0060173 166 0.014
fatty acid metabolic process GO:0006631 121 0.014
divalent metal ion transport GO:0070838 172 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
sequestering of calcium ion GO:0051208 18 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
metal ion homeostasis GO:0055065 189 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
forebrain development GO:0030900 302 0.013
regulation of t cell activation GO:0050863 170 0.013
multicellular organism growth GO:0035264 161 0.013
regulation of receptor binding GO:1900120 4 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
negative regulation of molecular function GO:0044092 258 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
protein ubiquitination GO:0016567 171 0.013
innate immune response GO:0045087 157 0.013
dna metabolic process GO:0006259 303 0.013
heart morphogenesis GO:0003007 178 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
leukocyte proliferation GO:0070661 172 0.013
epithelial cell proliferation GO:0050673 174 0.013
embryonic limb morphogenesis GO:0030326 126 0.012
neuronal action potential GO:0019228 54 0.012
mapk cascade GO:0000165 281 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
establishment of vesicle localization GO:0051650 81 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
muscle tissue development GO:0060537 308 0.012
response to oxidative stress GO:0006979 123 0.012
wound healing GO:0042060 157 0.012
response to light stimulus GO:0009416 135 0.012
limb morphogenesis GO:0035108 149 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
tissue homeostasis GO:0001894 115 0.012
regulation of protein localization GO:0032880 231 0.012
positive regulation of protein modification process GO:0031401 299 0.012
axon target recognition GO:0007412 4 0.012
action potential GO:0001508 78 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
embryonic appendage morphogenesis GO:0035113 126 0.012
cation homeostasis GO:0055080 212 0.012
lung development GO:0030324 164 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
urogenital system development GO:0001655 261 0.012
asymmetric stem cell division GO:0098722 3 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
protein modification by small protein conjugation or removal GO:0070647 207 0.012
negative regulation of wnt signaling pathway GO:0030178 73 0.012
peptidyl amino acid modification GO:0018193 336 0.011
leukocyte migration GO:0050900 124 0.011
establishment of organelle localization GO:0051656 122 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
response to organic cyclic compound GO:0014070 198 0.011
regulation of proteolysis GO:0030162 164 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
response to radiation GO:0009314 165 0.011
chromatin organization GO:0006325 206 0.011
glucose homeostasis GO:0042593 128 0.011
organic acid biosynthetic process GO:0016053 86 0.011
multicellular organismal signaling GO:0035637 91 0.011
mesenchyme development GO:0060485 152 0.011
regionalization GO:0003002 337 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
endocytosis GO:0006897 168 0.011
regulation of cell migration GO:0030334 219 0.011
morphogenesis of a polarized epithelium GO:0001738 37 0.011
leukocyte mediated immunity GO:0002443 174 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
cell type specific apoptotic process GO:0097285 268 0.011
regulation of hormone secretion GO:0046883 88 0.011
insulin secretion GO:0030073 89 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
sequestering of metal ion GO:0051238 19 0.011
cognition GO:0050890 149 0.011
regulation of protein processing GO:0070613 96 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
glycosylation GO:0070085 62 0.011
regulation of cytokine production GO:0001817 266 0.011
small molecule biosynthetic process GO:0044283 132 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
regulation of anatomical structure size GO:0090066 178 0.011
negative regulation of protein metabolic process GO:0051248 282 0.011
retina development in camera type eye GO:0060041 119 0.011
response to fibroblast growth factor GO:0071774 47 0.011
sensory perception of sound GO:0007605 97 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
anatomical structure homeostasis GO:0060249 145 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
steroid metabolic process GO:0008202 119 0.010
generation of precursor metabolites and energy GO:0006091 103 0.010
anion transport GO:0006820 177 0.010
purine nucleoside monophosphate metabolic process GO:0009126 81 0.010
response to nutrient levels GO:0031667 109 0.010
lymphocyte mediated immunity GO:0002449 139 0.010
positive regulation of cell activation GO:0050867 158 0.010
homeostasis of number of cells GO:0048872 210 0.010
regulation of purine nucleotide catabolic process GO:0033121 122 0.010
retrograde transport endosome to golgi GO:0042147 2 0.010
telencephalon development GO:0021537 186 0.010
vesicle localization GO:0051648 86 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
regulation of t cell proliferation GO:0042129 92 0.010
epithelial to mesenchymal transition GO:0001837 47 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
meiotic nuclear division GO:0007126 115 0.010
regulation of cellular catabolic process GO:0031329 242 0.010
regulation of leukocyte proliferation GO:0070663 121 0.010
myeloid cell differentiation GO:0030099 233 0.010
sulfur compound metabolic process GO:0006790 100 0.010
actin cytoskeleton organization GO:0030036 220 0.010
cell adhesion GO:0007155 329 0.010
protein glycosylation GO:0006486 55 0.010
glucose metabolic process GO:0006006 92 0.010
positive regulation of cell development GO:0010720 237 0.010
regulation of embryonic development GO:0045995 71 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010
ephrin receptor signaling pathway GO:0048013 20 0.010
spinal cord dorsal ventral patterning GO:0021513 23 0.010
rna interference GO:0016246 2 0.010
leukocyte differentiation GO:0002521 342 0.010

Wdpcp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.030
disease of anatomical entity DOID:7 0 0.030
eye and adnexa disease DOID:1492 0 0.027
sensory system disease DOID:0050155 0 0.027
musculoskeletal system disease DOID:17 0 0.018
cancer DOID:162 0 0.015
organ system cancer DOID:0050686 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
immune system disease DOID:2914 0 0.015
connective tissue disease DOID:65 0 0.015
eye disease DOID:5614 0 0.014
retinal disease DOID:5679 0 0.014
retinal degeneration DOID:8466 0 0.014
bone disease DOID:0080001 0 0.012
disease of metabolism DOID:0014667 0 0.011
hematopoietic system disease DOID:74 0 0.011
central nervous system disease DOID:331 0 0.010