Mus musculus

160 known processes

Lefty1

left right determination factor 1

(Aliases: Tgfb4,lefty-1,Stra3,lefty,AI450052,Ebaf,Leftb)

Lefty1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 337 0.747
mesendoderm development GO:0048382 3 0.592
mesoderm development GO:0007498 100 0.516
Zebrafish
heart morphogenesis GO:0003007 178 0.481
prechordal plate formation GO:0021501 1 0.466
negative regulation of cell proliferation GO:0008285 296 0.332
cardiac chamber morphogenesis GO:0003206 93 0.315
left lung development GO:0060459 4 0.314
regulation of transferase activity GO:0051338 263 0.308
neural tube development GO:0021915 160 0.302
epithelial tube morphogenesis GO:0060562 303 0.302
heart formation GO:0060914 16 0.302
Zebrafish
left lung morphogenesis GO:0060460 3 0.272
somite development GO:0061053 81 0.223
somitogenesis GO:0001756 69 0.223
morphogenesis of a branching structure GO:0001763 203 0.222
embryonic digit morphogenesis GO:0042733 56 0.219
camera type eye development GO:0043010 266 0.214
skeletal system morphogenesis GO:0048705 203 0.200
cell migration involved in gastrulation GO:0042074 13 0.200
blood vessel morphogenesis GO:0048514 285 0.199
regulation of fat cell differentiation GO:0045598 81 0.188
specification of organ identity GO:0010092 30 0.187
Zebrafish
gastrulation GO:0007369 116 0.185
regulation of tube size GO:0035150 57 0.178
regulation of kinase activity GO:0043549 249 0.178
digestive tract development GO:0048565 190 0.176
epithelial cell development GO:0002064 159 0.175
regulation of nodal signaling pathway GO:1900107 4 0.172
embryonic heart tube development GO:0035050 65 0.170
Zebrafish
epidermis development GO:0008544 187 0.170
determination of heart left right asymmetry GO:0061371 48 0.169
Zebrafish
mesenchyme development GO:0060485 152 0.169
Zebrafish
meiotic cell cycle GO:0051321 122 0.162
digestive tract morphogenesis GO:0048546 147 0.162
cell substrate adhesion GO:0031589 130 0.162
axial mesodermal cell fate commitment GO:0048322 1 0.161
cellular response to extracellular stimulus GO:0031668 81 0.160
male gamete generation GO:0048232 285 0.159
leukocyte differentiation GO:0002521 342 0.155
dorsal ventral neural tube patterning GO:0021904 28 0.154
determination of left right symmetry GO:0007368 80 0.154
regulation of bmp signaling pathway GO:0030510 60 0.147
lung development GO:0030324 164 0.142
regulation of cell activation GO:0050865 289 0.142
ras protein signal transduction GO:0007265 77 0.140
forebrain development GO:0030900 302 0.138
Zebrafish
negative regulation of cell development GO:0010721 169 0.137
mammary gland morphogenesis GO:0060443 54 0.137
regulation of protein localization GO:0032880 231 0.132
cytosolic calcium ion homeostasis GO:0051480 70 0.129
muscle tissue morphogenesis GO:0060415 53 0.126
deltoid tuberosity development GO:0035993 3 0.123
positive regulation of apoptotic process GO:0043065 217 0.122
peptidyl amino acid modification GO:0018193 336 0.121
muscle tissue development GO:0060537 308 0.121
wnt signaling pathway GO:0016055 188 0.118
regulation of cellular component biogenesis GO:0044087 181 0.116
cardiac muscle tissue development GO:0048738 130 0.115
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.114
positive regulation of cell migration GO:0030335 109 0.113
mesenchymal cell differentiation GO:0048762 107 0.113
carbohydrate metabolic process GO:0005975 230 0.112
germ cell development GO:0007281 185 0.112
regulation of anatomical structure size GO:0090066 178 0.111
telencephalon development GO:0021537 186 0.109
regulation of response to wounding GO:1903034 189 0.108
embryonic organ morphogenesis GO:0048562 276 0.107
cell adhesion GO:0007155 329 0.107
regulation of cell adhesion GO:0030155 154 0.106
embryonic skeletal system development GO:0048706 120 0.106
regulation of establishment of protein localization GO:0070201 181 0.105
negative regulation of nodal signaling pathway GO:1900108 3 0.103
cellular homeostasis GO:0019725 240 0.103
regulation of neuron differentiation GO:0045664 281 0.102
calcium ion homeostasis GO:0055074 127 0.101
macromolecule catabolic process GO:0009057 281 0.101
axial mesodermal cell fate specification GO:0048327 1 0.099
small gtpase mediated signal transduction GO:0007264 97 0.097
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.097
floor plate morphogenesis GO:0033505 3 0.097
activation of adenylate cyclase activity GO:0007190 4 0.096
microtubule based process GO:0007017 236 0.096
limb development GO:0060173 166 0.096
angiogenesis GO:0001525 201 0.096
gland development GO:0048732 330 0.096
cardiac septum development GO:0003279 59 0.095
positive regulation of kinase activity GO:0033674 155 0.095
rhythmic process GO:0048511 174 0.094
chemotaxis GO:0006935 247 0.093
developmental growth involved in morphogenesis GO:0060560 138 0.092
stem cell development GO:0048864 219 0.092
cardiocyte differentiation GO:0035051 87 0.090
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.088
limb morphogenesis GO:0035108 149 0.088
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.088
positive regulation of cell activation GO:0050867 158 0.088
negative regulation of neuron projection development GO:0010977 50 0.087
positive regulation of neuron differentiation GO:0045666 141 0.087
cellular response to nutrient levels GO:0031669 64 0.087
epithelial tube formation GO:0072175 130 0.087
neural tube closure GO:0001843 90 0.086
morphogenesis of a branching epithelium GO:0061138 193 0.086
nodal signaling pathway GO:0038092 10 0.086
respiratory system development GO:0060541 190 0.086
cell fate commitment GO:0045165 210 0.085
regulation of gtp catabolic process GO:0033124 113 0.085
spemann organizer formation GO:0060061 2 0.085
developmental maturation GO:0021700 193 0.084
ameboidal type cell migration GO:0001667 128 0.084
striated muscle tissue development GO:0014706 293 0.083
negative regulation of cellular component organization GO:0051129 194 0.082
cell matrix adhesion GO:0007160 68 0.082
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.081
neural tube patterning GO:0021532 43 0.081
neural crest cell differentiation GO:0014033 54 0.081
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.080
mesonephric tubule morphogenesis GO:0072171 63 0.079
endocrine system development GO:0035270 98 0.076
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.075
positive regulation of protein phosphorylation GO:0001934 242 0.074
skeletal muscle cell differentiation GO:0035914 66 0.073
vascular process in circulatory system GO:0003018 62 0.073
regulation of cellular response to stress GO:0080135 159 0.073
b cell activation GO:0042113 161 0.073
skeletal system development GO:0001501 356 0.072
stem cell differentiation GO:0048863 268 0.071
innate immune response GO:0045087 157 0.070
paraxial mesodermal cell fate commitment GO:0048343 2 0.070
positive regulation of transcription by glucose GO:0046016 3 0.069
regulation of androgen receptor signaling pathway GO:0060765 3 0.068
regulation of cell migration GO:0030334 219 0.068
positive regulation of protein modification process GO:0031401 299 0.068
cellular amino acid metabolic process GO:0006520 103 0.067
regulation of cell motility GO:2000145 236 0.067
action potential GO:0001508 78 0.067
calcium ion transport GO:0006816 159 0.067
homeostasis of number of cells GO:0048872 210 0.066
regulation of secretion by cell GO:1903530 249 0.066
regulation of organ morphogenesis GO:2000027 144 0.065
cellular chemical homeostasis GO:0055082 215 0.065
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.065
metanephros morphogenesis GO:0003338 24 0.064
meiotic nuclear division GO:0007126 115 0.064
regulation of cellular ketone metabolic process GO:0010565 66 0.063
dna metabolic process GO:0006259 303 0.063
regulation of t cell activation GO:0050863 170 0.063
sequestering of calcium ion GO:0051208 18 0.063
cell division GO:0051301 120 0.063
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.062
syncytium formation GO:0006949 43 0.062
wound healing GO:0042060 157 0.062
aromatic compound catabolic process GO:0019439 286 0.061
carbohydrate derivative biosynthetic process GO:1901137 183 0.061
canonical wnt signaling pathway GO:0060070 130 0.061
organonitrogen compound biosynthetic process GO:1901566 192 0.060
t cell activation GO:0042110 289 0.060
segmentation GO:0035282 93 0.060
divalent inorganic cation transport GO:0072511 178 0.060
pallium development GO:0021543 120 0.060
positive regulation of leukocyte differentiation GO:1902107 86 0.060
positive regulation of mapk cascade GO:0043410 170 0.060
amine metabolic process GO:0009308 45 0.060
regulation of cellular amino acid metabolic process GO:0006521 5 0.060
branching morphogenesis of an epithelial tube GO:0048754 159 0.058
muscle system process GO:0003012 141 0.058
cardiac septum morphogenesis GO:0060411 46 0.057
endodermal cell fate specification GO:0001714 4 0.057
organic hydroxy compound metabolic process GO:1901615 203 0.057
floor plate formation GO:0021508 2 0.057
smoothened signaling pathway GO:0007224 105 0.057
ventral midline development GO:0007418 4 0.057
skin development GO:0043588 220 0.057
regulation of membrane potential GO:0042391 192 0.056
positive regulation of wnt signaling pathway GO:0030177 45 0.056
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.055
embryonic axis specification GO:0000578 30 0.055
rho protein signal transduction GO:0007266 32 0.055
purine containing compound metabolic process GO:0072521 311 0.054
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.054
cellular amine metabolic process GO:0044106 44 0.054
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.054
negative regulation of phosphate metabolic process GO:0045936 184 0.054
negative regulation of synapse assembly GO:0051964 3 0.053
regulation of secretion GO:0051046 274 0.053
positive regulation of nucleotide metabolic process GO:0045981 114 0.053
embryonic limb morphogenesis GO:0030326 126 0.053
t cell differentiation GO:0030217 174 0.052
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.052
nucleoside phosphate biosynthetic process GO:1901293 79 0.052
renal system development GO:0072001 225 0.052
positive regulation of cell motility GO:2000147 116 0.052
cellular response to starvation GO:0009267 57 0.052
female gonad development GO:0008585 71 0.052
spermatogenesis GO:0007283 284 0.051
synaptic transmission GO:0007268 329 0.050
cell growth GO:0016049 130 0.050
guanosine containing compound catabolic process GO:1901069 144 0.050
positive regulation of nervous system development GO:0051962 221 0.050
gtp metabolic process GO:0046039 144 0.050
mapk cascade GO:0000165 281 0.049
development of primary female sexual characteristics GO:0046545 73 0.049
leukotriene production involved in inflammatory response GO:0002540 2 0.049
regulation of lymphocyte activation GO:0051249 240 0.049
regulation of canonical wnt signaling pathway GO:0060828 82 0.049
organophosphate catabolic process GO:0046434 232 0.048
anatomical structure homeostasis GO:0060249 145 0.048
regulation of chondrocyte differentiation GO:0032330 33 0.048
regulation of leukocyte differentiation GO:1902105 159 0.048
purine nucleoside metabolic process GO:0042278 241 0.048
gonad development GO:0008406 141 0.047
cell recognition GO:0008037 83 0.047
connective tissue development GO:0061448 179 0.047
organophosphate biosynthetic process GO:0090407 122 0.047
protein secretion GO:0009306 111 0.047
conditioned taste aversion GO:0001661 4 0.047
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.046
regulation of ion transport GO:0043269 215 0.046
cell maturation GO:0048469 127 0.046
lymphocyte differentiation GO:0030098 242 0.046
primary neural tube formation GO:0014020 95 0.046
axonogenesis GO:0007409 274 0.046
nucleobase containing small molecule metabolic process GO:0055086 352 0.045
negative regulation of molecular function GO:0044092 258 0.045
embryonic heart tube anterior posterior pattern specification GO:0035054 3 0.045
sensory organ morphogenesis GO:0090596 242 0.045
ribonucleotide metabolic process GO:0009259 291 0.045
metal ion homeostasis GO:0055065 189 0.045
positive regulation of protein transport GO:0051222 93 0.045
regulation of chemotaxis GO:0050920 53 0.045
determination of digestive tract left right asymmetry GO:0071907 1 0.045
positive regulation of lymphocyte activation GO:0051251 140 0.044
ensheathment of neurons GO:0007272 76 0.044
cytokine secretion GO:0050663 72 0.044
bmp signaling pathway GO:0030509 93 0.044
nucleotide metabolic process GO:0009117 332 0.044
ureteric bud development GO:0001657 94 0.044
intracellular protein transport GO:0006886 204 0.044
mesonephric epithelium development GO:0072163 94 0.044
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.044
cell type specific apoptotic process GO:0097285 268 0.043
renal tubule development GO:0061326 87 0.043
ribose phosphate biosynthetic process GO:0046390 59 0.043
nucleoside triphosphate catabolic process GO:0009143 205 0.043
positive regulation of protein kinase activity GO:0045860 144 0.043
positive regulation of dna endoreduplication GO:0032877 2 0.043
negative regulation of gastrulation GO:2000542 3 0.042
gliogenesis GO:0042063 141 0.042
response to extracellular stimulus GO:0009991 127 0.042
b cell differentiation GO:0030183 78 0.042
positive regulation of transferase activity GO:0051347 167 0.042
nucleoside phosphate catabolic process GO:1901292 222 0.042
neuronal action potential GO:0019228 54 0.041
nephron tubule morphogenesis GO:0072078 68 0.041
skeletal muscle organ development GO:0060538 163 0.041
positive regulation of protein secretion GO:0050714 52 0.041
response to transforming growth factor beta GO:0071559 88 0.041
central nervous system neuron differentiation GO:0021953 162 0.041
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.040
regulation of leukocyte apoptotic process GO:2000106 56 0.040
regulation of cellular amine metabolic process GO:0033238 20 0.040
nephron epithelium development GO:0072009 92 0.040
erythrocyte differentiation GO:0030218 88 0.040
retina development in camera type eye GO:0060041 119 0.040
endoderm development GO:0007492 45 0.040
purine ribonucleoside catabolic process GO:0046130 205 0.040
divalent inorganic cation homeostasis GO:0072507 138 0.040
placenta development GO:0001890 140 0.039
cytoplasmic transport GO:0016482 234 0.039
neuron fate specification GO:0048665 30 0.039
regulation of cellular component size GO:0032535 121 0.039
carbon catabolite regulation of transcription GO:0045990 4 0.039
carbon catabolite activation of transcription GO:0045991 4 0.039
ureteric bud morphogenesis GO:0060675 62 0.038
kidney epithelium development GO:0072073 121 0.038
response to organonitrogen compound GO:0010243 246 0.038
regulation of vasculature development GO:1901342 88 0.038
regulation of mapk cascade GO:0043408 248 0.038
regulation of cellular catabolic process GO:0031329 242 0.038
ribonucleotide biosynthetic process GO:0009260 59 0.038
ovulation cycle GO:0042698 59 0.038
cellular nitrogen compound catabolic process GO:0044270 280 0.038
phenol containing compound metabolic process GO:0018958 60 0.038
blood circulation GO:0008015 195 0.037
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.037
regulation of neuron projection development GO:0010975 169 0.037
endothelium development GO:0003158 45 0.037
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.037
ventricular septum morphogenesis GO:0060412 27 0.037
nucleoside triphosphate metabolic process GO:0009141 230 0.037
multi multicellular organism process GO:0044706 109 0.037
positive regulation of cytokine production GO:0001819 174 0.036
myeloid leukocyte differentiation GO:0002573 119 0.036
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.036
regulation of nucleotide metabolic process GO:0006140 169 0.036
defense response to other organism GO:0098542 197 0.036
organelle fission GO:0048285 170 0.036
negative regulation of phosphorus metabolic process GO:0010563 184 0.036
nephron development GO:0072006 109 0.036
axon ensheathment GO:0008366 76 0.035
positive regulation of ras gtpase activity GO:0032320 65 0.035
epithelial cell proliferation GO:0050673 174 0.035
endothelial cell differentiation GO:0045446 41 0.035
tendon formation GO:0035992 4 0.035
mesonephric tubule development GO:0072164 94 0.035
ribonucleoside catabolic process GO:0042454 206 0.035
regulation of t cell differentiation GO:0045580 83 0.035
lens morphogenesis in camera type eye GO:0002089 24 0.034
defense response to bacterium GO:0042742 119 0.034
regulation of wnt signaling pathway GO:0030111 123 0.034
oocyte construction GO:0007308 2 0.034
regulation of blood vessel size GO:0050880 56 0.034
positive regulation of cell death GO:0010942 224 0.034
nucleoside phosphate metabolic process GO:0006753 338 0.034
muscle cell differentiation GO:0042692 261 0.034
regulation of nucleotide catabolic process GO:0030811 122 0.034
sequestering of metal ion GO:0051238 19 0.034
regulation of purine nucleotide metabolic process GO:1900542 169 0.034
alcohol metabolic process GO:0006066 116 0.034
multicellular organismal signaling GO:0035637 91 0.034
cartilage development GO:0051216 140 0.034
endochondral bone morphogenesis GO:0060350 50 0.034
b cell proliferation GO:0042100 53 0.034
cellular response to lipid GO:0071396 145 0.033
regulation of cell size GO:0008361 72 0.033
negative regulation of neuron projection regeneration GO:0070571 3 0.033
response to monosaccharide GO:0034284 67 0.033
formation of primary germ layer GO:0001704 77 0.033
regulation of protein transport GO:0051223 163 0.033
negative regulation of nervous system development GO:0051961 156 0.033
regulation of inflammatory response GO:0050727 147 0.033
circulatory system process GO:0003013 197 0.033
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.033
glycosyl compound metabolic process GO:1901657 246 0.033
cation homeostasis GO:0055080 212 0.033
hematopoietic progenitor cell differentiation GO:0002244 143 0.032
organic cyclic compound catabolic process GO:1901361 295 0.032
oogenesis GO:0048477 56 0.032
regulation of smoothened signaling pathway GO:0008589 58 0.032
purine ribonucleotide metabolic process GO:0009150 290 0.032
cardiac chamber development GO:0003205 108 0.032
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.032
lens development in camera type eye GO:0002088 62 0.032
protein catabolic process GO:0030163 221 0.032
response to sterol GO:0036314 4 0.032
spermatid differentiation GO:0048515 115 0.032
syncytium formation by plasma membrane fusion GO:0000768 42 0.032
renal capsule morphogenesis GO:0072128 1 0.032
purine nucleoside triphosphate metabolic process GO:0009144 226 0.032
response to organic cyclic compound GO:0014070 198 0.032
regulation of vascular wound healing GO:0061043 2 0.032
negative regulation of homeostatic process GO:0032845 71 0.032
cellular carbohydrate metabolic process GO:0044262 119 0.031
kidney development GO:0001822 213 0.031
purine nucleotide metabolic process GO:0006163 302 0.031
diencephalon development GO:0021536 63 0.031
Zebrafish
embryonic epithelial tube formation GO:0001838 130 0.031
nucleoside metabolic process GO:0009116 246 0.031
ossification GO:0001503 216 0.031
nitrogen compound transport GO:0071705 271 0.031
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.030
pyramidal neuron migration GO:0021852 1 0.030
organic hydroxy compound transport GO:0015850 93 0.030
regulation of protein secretion GO:0050708 82 0.030
negative regulation of growth GO:0045926 99 0.030
cellular divalent inorganic cation homeostasis GO:0072503 127 0.030
positive regulation of bmp signaling pathway GO:0030513 23 0.030
heterocycle catabolic process GO:0046700 280 0.030
embryonic heart tube morphogenesis GO:0003143 51 0.030
response to radiation GO:0009314 165 0.030
protein maturation GO:0051604 176 0.029
cation transport GO:0006812 399 0.029
g protein coupled receptor signaling pathway GO:0007186 243 0.029
left right pattern formation GO:0060972 23 0.029
tendon cell differentiation GO:0035990 4 0.029
response to growth factor GO:0070848 198 0.029
positive regulation of stem cell proliferation GO:2000648 59 0.029
spermatid development GO:0007286 108 0.029
glial cell differentiation GO:0010001 131 0.029
actin cytoskeleton organization GO:0030036 220 0.029
mesenchymal cell development GO:0014031 93 0.029
mesangial cell development GO:0072143 4 0.029
extracellular matrix organization GO:0030198 147 0.029
axial mesoderm development GO:0048318 8 0.029
regulation of lymphocyte proliferation GO:0050670 117 0.029
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.028
dorsal ventral axon guidance GO:0033563 3 0.028
blastocyst development GO:0001824 80 0.028
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.028
prostate gland stromal morphogenesis GO:0060741 2 0.028
pituitary gland development GO:0021983 38 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.028
female sex differentiation GO:0046660 84 0.028
hormone secretion GO:0046879 128 0.028
inflammatory response GO:0006954 244 0.028
regulation of receptor activity GO:0010469 41 0.027
divalent metal ion transport GO:0070838 172 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
nephron epithelium morphogenesis GO:0072088 68 0.027
regulation of intracellular transport GO:0032386 159 0.027
regulation of wound healing GO:0061041 40 0.027
regulation of lipid metabolic process GO:0019216 118 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
cellular response to growth factor stimulus GO:0071363 197 0.027
positive regulation of hydrolase activity GO:0051345 148 0.027
lipid localization GO:0010876 126 0.027
peripheral nervous system development GO:0007422 53 0.027
positive regulation of transcription from rna polymerase iii promoter GO:0045945 1 0.027
positive regulation of kidney development GO:0090184 28 0.027
regulation of protein catabolic process GO:0042176 108 0.027
regulation of cell cycle GO:0051726 281 0.027
myeloid cell homeostasis GO:0002262 114 0.027
trachea formation GO:0060440 3 0.027
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.027
positive regulation of glial cell proliferation GO:0060252 4 0.027
ribonucleoside triphosphate catabolic process GO:0009203 199 0.026
nuclear division GO:0000280 158 0.026
extraocular skeletal muscle development GO:0002074 2 0.026
regulation of protein kinase activity GO:0045859 232 0.026
fat cell differentiation GO:0045444 160 0.026
coagulation GO:0050817 78 0.026
ovarian follicle development GO:0001541 40 0.026
peptidyl tyrosine phosphorylation GO:0018108 143 0.026
response to acid chemical GO:0001101 111 0.026
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.026
regulation of kidney development GO:0090183 40 0.026
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.026
regulation of ossification GO:0030278 112 0.026
trophectodermal cellular morphogenesis GO:0001831 3 0.026
spleen development GO:0048536 39 0.026
carbohydrate derivative catabolic process GO:1901136 231 0.026
ribonucleoside metabolic process GO:0009119 245 0.026
regulation of b cell proliferation GO:0030888 39 0.026
respiratory tube development GO:0030323 167 0.025
protein targeting GO:0006605 143 0.025
positive regulation of map kinase activity GO:0043406 84 0.025
positive regulation of ossification GO:0045778 47 0.025
regulation of transcription by glucose GO:0046015 3 0.025
female somatic sex determination GO:0019101 1 0.025
nucleotide biosynthetic process GO:0009165 78 0.025
renal vesicle morphogenesis GO:0072077 15 0.025
steroid metabolic process GO:0008202 119 0.025
cell differentiation involved in kidney development GO:0061005 33 0.025
positive regulation of wound healing GO:0090303 17 0.025
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.025
mesoderm formation GO:0001707 62 0.025
negative regulation of hexokinase activity GO:1903300 4 0.025
negative regulation of wnt signaling pathway GO:0030178 73 0.025
negative regulation of cell activation GO:0050866 111 0.025
positive regulation of vasoconstriction GO:0045907 4 0.025
central nervous system neuron development GO:0021954 67 0.025
negative regulation of receptor activity GO:2000272 5 0.025
somite rostral caudal axis specification GO:0032525 13 0.024
outflow tract morphogenesis GO:0003151 53 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
negative regulation of cartilage development GO:0061037 17 0.024
regulation of rho protein signal transduction GO:0035023 71 0.024
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
regulation of organelle organization GO:0033043 289 0.024
detection of external stimulus GO:0009581 61 0.024
cellular metal ion homeostasis GO:0006875 151 0.024
cellular calcium ion homeostasis GO:0006874 119 0.024
regulation of proteolysis GO:0030162 164 0.024
multicellular organism growth GO:0035264 161 0.024
establishment of endothelial blood brain barrier GO:0014045 3 0.024
hypothalamus cell migration GO:0021855 5 0.024
secondary heart field specification GO:0003139 6 0.024
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.024
intracellular receptor signaling pathway GO:0030522 74 0.024
oocyte axis specification GO:0007309 2 0.024
cell cell recognition GO:0009988 44 0.024
regulation of cell substrate adhesion GO:0010810 73 0.024
regulation of map kinase activity GO:0043405 120 0.024
organic hydroxy compound biosynthetic process GO:1901617 77 0.023
metanephric nephron morphogenesis GO:0072273 19 0.023
positive regulation of secretion by cell GO:1903532 114 0.023
tissue remodeling GO:0048771 102 0.023
paraxial mesodermal cell differentiation GO:0048342 2 0.023
appendage morphogenesis GO:0035107 149 0.023
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.023
negative regulation of fat cell differentiation GO:0045599 36 0.023
regulation of muscle tissue development GO:1901861 97 0.023
cardiac ventricle development GO:0003231 83 0.023
guanosine containing compound metabolic process GO:1901068 144 0.023
metanephric collecting duct development GO:0072205 7 0.023
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.023
adaptive immune response GO:0002250 155 0.023

Lefty1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.102
disease of anatomical entity DOID:7 0 0.102
nervous system disease DOID:863 0 0.102
eye and adnexa disease DOID:1492 0 0.057
eye disease DOID:5614 0 0.031
retinal disease DOID:5679 0 0.024
retinal degeneration DOID:8466 0 0.024