Mus musculus

70 known processes

Slc46a2

solute carrier family 46, member 2

(Aliases: 5430429N04Rik,TSO-1C12,Ly110,Tscot)

Slc46a2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of peptidase activity GO:0052547 96 0.173
defense response to other organism GO:0098542 197 0.147
apoptotic signaling pathway GO:0097190 306 0.142
epidermis development GO:0008544 187 0.137
cellular lipid metabolic process GO:0044255 323 0.134
intermediate filament based process GO:0045103 27 0.110
hair follicle morphogenesis GO:0031069 29 0.101
organic hydroxy compound metabolic process GO:1901615 203 0.099
inflammatory response GO:0006954 244 0.090
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.089
hair cycle GO:0042633 90 0.087
regulation of epithelial cell proliferation GO:0050678 141 0.086
cytokine production GO:0001816 319 0.085
regulation of hydrolase activity GO:0051336 246 0.083
negative regulation of cellular protein metabolic process GO:0032269 247 0.082
reactive oxygen species metabolic process GO:0072593 84 0.077
lipid biosynthetic process GO:0008610 179 0.076
regulation of endopeptidase activity GO:0052548 89 0.074
regulation of epidermis development GO:0045682 33 0.073
multicellular organismal signaling GO:0035637 91 0.071
cellular amino acid metabolic process GO:0006520 103 0.071
cell adhesion GO:0007155 329 0.070
protein maturation GO:0051604 176 0.069
cellular metal ion homeostasis GO:0006875 151 0.069
negative regulation of cell proliferation GO:0008285 296 0.066
multicellular organismal water homeostasis GO:0050891 23 0.064
regulation of defense response GO:0031347 233 0.063
mapk cascade GO:0000165 281 0.062
hair follicle development GO:0001942 85 0.060
cellular chemical homeostasis GO:0055082 215 0.060
sa node cell action potential GO:0086015 4 0.059
negative regulation of protein processing GO:0010955 79 0.058
protein processing GO:0016485 163 0.058
cell cell adhesion GO:0098609 41 0.057
regulation of mapk cascade GO:0043408 248 0.057
cation homeostasis GO:0055080 212 0.057
fatty acid metabolic process GO:0006631 121 0.055
metal ion homeostasis GO:0055065 189 0.054
regulation of response to wounding GO:1903034 189 0.054
oxidation reduction process GO:0055114 342 0.052
regulation of transferase activity GO:0051338 263 0.051
regulation of blood pressure GO:0008217 93 0.050
av node cell to bundle of his cell communication GO:0086067 2 0.050
regulation of secretion by cell GO:1903530 249 0.050
action potential GO:0001508 78 0.049
extrinsic apoptotic signaling pathway GO:0097191 126 0.048
negative regulation of phosphate metabolic process GO:0045936 184 0.048
regulation of body fluid levels GO:0050878 162 0.048
regulation of proteolysis GO:0030162 164 0.048
regulation of secretion GO:0051046 274 0.048
water homeostasis GO:0030104 27 0.047
negative regulation of proteolysis GO:0045861 74 0.047
regulation of water loss via skin GO:0033561 16 0.047
muscle cell differentiation GO:0042692 261 0.045
epithelial cell proliferation GO:0050673 174 0.044
immune effector process GO:0002252 321 0.044
negative regulation of hydrolase activity GO:0051346 71 0.044
cellular homeostasis GO:0019725 240 0.043
establishment of skin barrier GO:0061436 14 0.043
positive regulation of mapk cascade GO:0043410 170 0.042
cell type specific apoptotic process GO:0097285 268 0.042
posttranscriptional regulation of gene expression GO:0010608 155 0.042
positive regulation of cytokine production GO:0001819 174 0.041
positive regulation of growth GO:0045927 104 0.041
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.041
regulation of hormone levels GO:0010817 211 0.040
cellular amine metabolic process GO:0044106 44 0.040
skin morphogenesis GO:0043589 38 0.040
calcium ion homeostasis GO:0055074 127 0.040
regulation of muscle contraction GO:0006937 49 0.039
regulation of membrane potential GO:0042391 192 0.039
response to radiation GO:0009314 165 0.039
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.039
wound healing GO:0042060 157 0.038
circulatory system process GO:0003013 197 0.038
hematopoietic progenitor cell differentiation GO:0002244 143 0.038
male gamete generation GO:0048232 285 0.038
cation transport GO:0006812 399 0.037
keratinocyte differentiation GO:0030216 48 0.037
regulation of cysteine type endopeptidase activity GO:2000116 65 0.036
regulation of cytokine production GO:0001817 266 0.036
skin development GO:0043588 220 0.035
negative regulation of protein maturation GO:1903318 79 0.035
regulation of protein kinase activity GO:0045859 232 0.035
intermediate filament cytoskeleton organization GO:0045104 26 0.035
divalent inorganic cation homeostasis GO:0072507 138 0.035
sulfur compound metabolic process GO:0006790 100 0.034
stem cell differentiation GO:0048863 268 0.034
regulation of anatomical structure size GO:0090066 178 0.033
lens development in camera type eye GO:0002088 62 0.032
blood circulation GO:0008015 195 0.032
regulation of systemic arterial blood pressure GO:0003073 61 0.032
alcohol metabolic process GO:0006066 116 0.032
organic hydroxy compound biosynthetic process GO:1901617 77 0.032
regulation of protein transport GO:0051223 163 0.031
regulation of protein processing GO:0070613 96 0.031
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.031
sphingolipid biosynthetic process GO:0030148 26 0.030
nucleoside phosphate metabolic process GO:0006753 338 0.029
negative regulation of peptidase activity GO:0010466 46 0.029
regulation of system process GO:0044057 200 0.029
cellular response to lipid GO:0071396 145 0.029
epithelial cell development GO:0002064 159 0.029
muscle tissue development GO:0060537 308 0.028
regulation of renin secretion into blood stream GO:1900133 4 0.028
small gtpase mediated signal transduction GO:0007264 97 0.028
organic cyclic compound catabolic process GO:1901361 295 0.028
small molecule biosynthetic process GO:0044283 132 0.028
ribose phosphate metabolic process GO:0019693 291 0.028
sensory perception GO:0007600 245 0.028
spermatogenesis GO:0007283 284 0.027
regulation of purine nucleotide metabolic process GO:1900542 169 0.027
regulation of ossification GO:0030278 112 0.027
regulation of kinase activity GO:0043549 249 0.027
wnt signaling pathway GO:0016055 188 0.027
defense response to bacterium GO:0042742 119 0.026
glycerolipid metabolic process GO:0046486 122 0.026
regulation of receptor activity GO:0010469 41 0.026
regulation of reactive oxygen species metabolic process GO:2000377 40 0.026
regulation of membrane depolarization during cardiac muscle cell action potential GO:1900825 1 0.026
innate immune response GO:0045087 157 0.026
amine metabolic process GO:0009308 45 0.026
blood vessel morphogenesis GO:0048514 285 0.026
membrane organization GO:0061024 245 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
regulation of protein localization GO:0032880 231 0.025
organonitrogen compound biosynthetic process GO:1901566 192 0.025
cellular response to cytokine stimulus GO:0071345 189 0.025
striated muscle cell development GO:0055002 125 0.025
regulation of cellular ketone metabolic process GO:0010565 66 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
negative regulation of endopeptidase activity GO:0010951 44 0.024
cellular ketone metabolic process GO:0042180 84 0.024
muscle contraction GO:0006936 101 0.024
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.024
regulation of keratinocyte differentiation GO:0045616 11 0.024
regulation of ion transport GO:0043269 215 0.024
molting cycle GO:0042303 90 0.023
muscle system process GO:0003012 141 0.023
t cell proliferation GO:0042098 120 0.023
epidermis morphogenesis GO:0048730 33 0.023
lymphocyte proliferation GO:0046651 164 0.023
positive regulation of ossification GO:0045778 47 0.023
regulation of cellular catabolic process GO:0031329 242 0.023
cellular ion homeostasis GO:0006873 165 0.022
ion transmembrane transport GO:0034220 361 0.022
purine nucleotide metabolic process GO:0006163 302 0.022
sphingolipid metabolic process GO:0006665 45 0.022
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.022
membrane lipid metabolic process GO:0006643 53 0.022
purine containing compound metabolic process GO:0072521 311 0.022
protein oligomerization GO:0051259 67 0.021
regulation of lymphocyte apoptotic process GO:0070228 41 0.021
regulation of interleukin 6 production GO:0032675 55 0.021
hormone metabolic process GO:0042445 86 0.021
nitrogen compound transport GO:0071705 271 0.021
Mouse
transmembrane transport GO:0055085 412 0.020
regulation of cellular amino acid metabolic process GO:0006521 5 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
transmission of nerve impulse GO:0019226 76 0.020
phospholipid metabolic process GO:0006644 87 0.020
cell cell junction organization GO:0045216 72 0.020
cell communication by electrical coupling involved in cardiac conduction GO:0086064 2 0.020
single organism cell adhesion GO:0098602 156 0.020
cell communication by chemical coupling GO:0010643 2 0.020
intermediate filament organization GO:0045109 15 0.020
regulation of saliva secretion GO:0046877 2 0.020
negative regulation of response to wounding GO:1903035 77 0.020
cellular calcium ion homeostasis GO:0006874 119 0.020
reactive oxygen species biosynthetic process GO:1903409 8 0.020
regulation of inflammatory response GO:0050727 147 0.020
nucleotide metabolic process GO:0009117 332 0.020
sodium ion transmembrane transport GO:0035725 49 0.020
endocytosis GO:0006897 168 0.020
sensory perception of sound GO:0007605 97 0.019
macromolecule catabolic process GO:0009057 281 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
regulation of wound healing GO:0061041 40 0.019
milk ejection GO:0060156 1 0.019
neuronal action potential GO:0019228 54 0.019
glycerophospholipid metabolic process GO:0006650 71 0.019
intrinsic apoptotic signaling pathway GO:0097193 132 0.019
axon ensheathment GO:0008366 76 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
regulation of vesicle mediated transport GO:0060627 139 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
regulation of protein maturation GO:1903317 96 0.019
regulation of neuron differentiation GO:0045664 281 0.019
hepatocyte apoptotic process GO:0097284 11 0.018
regulation of membrane depolarization during action potential GO:0098902 1 0.018
organophosphate biosynthetic process GO:0090407 122 0.018
extracellular structure organization GO:0043062 148 0.018
leukocyte proliferation GO:0070661 172 0.018
regulation of cellular amine metabolic process GO:0033238 20 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
atrial ventricular junction remodeling GO:0003294 2 0.018
regulation of thyroid hormone generation GO:2000609 4 0.018
negative regulation of neuron death GO:1901215 98 0.018
lymphocyte mediated immunity GO:0002449 139 0.018
response to organonitrogen compound GO:0010243 246 0.018
interleukin 6 production GO:0032635 58 0.018
g protein coupled purinergic nucleotide receptor signaling pathway GO:0035589 1 0.018
tissue regeneration GO:0042246 22 0.018
extracellular matrix organization GO:0030198 147 0.018
regulation of hair follicle development GO:0051797 9 0.018
membrane depolarization GO:0051899 64 0.017
foramen ovale closure GO:0035922 1 0.017
protein secretion GO:0009306 111 0.017
carbohydrate metabolic process GO:0005975 230 0.017
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.017
fertilization GO:0009566 127 0.017
positive regulation of interleukin 8 production GO:0032757 2 0.017
multi multicellular organism process GO:0044706 109 0.017
cellular modified amino acid metabolic process GO:0006575 63 0.017
regulation of protein serine threonine kinase activity GO:0071900 157 0.017
positive regulation of apoptotic signaling pathway GO:2001235 95 0.017
regulation of map kinase activity GO:0043405 120 0.016
ossification GO:0001503 216 0.016
defecation GO:0030421 1 0.016
sequestering of metal ion GO:0051238 19 0.016
translation GO:0006412 93 0.016
negative regulation of transferase activity GO:0051348 85 0.016
keratinocyte development GO:0003334 10 0.016
positive regulation of transferase activity GO:0051347 167 0.016
protein catabolic process GO:0030163 221 0.016
carbohydrate homeostasis GO:0033500 128 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
ensheathment of neurons GO:0007272 76 0.016
cytokine metabolic process GO:0042107 71 0.016
conditioned taste aversion GO:0001661 4 0.016
sensory organ morphogenesis GO:0090596 242 0.016
regulation of hair cycle GO:0042634 11 0.016
positive regulation of epithelial cell proliferation GO:0050679 68 0.016
regulation of protein catabolic process GO:0042176 108 0.016
regulation of action potential GO:0098900 4 0.015
response to insulin GO:0032868 100 0.015
cytosolic calcium ion transport GO:0060401 48 0.015
i kappab kinase nf kappab signaling GO:0007249 85 0.015
regulation of neurotransmitter levels GO:0001505 87 0.015
exocytosis GO:0006887 121 0.015
mesangial cell differentiation GO:0072007 4 0.015
myelination GO:0042552 74 0.015
negative regulation of molecular function GO:0044092 258 0.015
response to light stimulus GO:0009416 135 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.015
cation transmembrane transport GO:0098655 266 0.015
reactive nitrogen species metabolic process GO:2001057 0 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.015
positive regulation of kinase activity GO:0033674 155 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
sequestering of calcium ion GO:0051208 18 0.015
bone remodeling GO:0046849 53 0.014
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.014
positive regulation of secretion GO:0051047 130 0.014
negative regulation of neuron apoptotic process GO:0043524 92 0.014
calcium ion transport GO:0006816 159 0.014
columnar cuboidal epithelial cell development GO:0002066 29 0.014
ascending thin limb development GO:0072021 2 0.014
negative regulation of growth GO:0045926 99 0.014
aromatic compound catabolic process GO:0019439 286 0.014
peptide hormone secretion GO:0030072 109 0.014
regulation of translation GO:0006417 71 0.014
membrane lipid biosynthetic process GO:0046467 32 0.014
regeneration GO:0031099 38 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
regulation of blood circulation GO:1903522 93 0.014
positive regulation of hair follicle development GO:0051798 6 0.014
myeloid cell differentiation GO:0030099 233 0.014
regulation of cytoplasmic transport GO:1903649 112 0.013
sodium ion transport GO:0006814 73 0.013
regulation of actin filament based process GO:0032970 99 0.013
actin filament organization GO:0007015 113 0.013
detection of abiotic stimulus GO:0009582 60 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
neuron death GO:0070997 154 0.013
regulation of osteoblast differentiation GO:0045667 67 0.013
negative regulation of nervous system development GO:0051961 156 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
regulation of cellular response to stress GO:0080135 159 0.013
binding of sperm to zona pellucida GO:0007339 34 0.013
viral gene expression GO:0019080 3 0.013
biomineral tissue development GO:0031214 64 0.013
neuromuscular process GO:0050905 99 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
negative regulation of immune system process GO:0002683 209 0.013
synaptic transmission GO:0007268 329 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
homeostasis of number of cells GO:0048872 210 0.013
adaptive immune response GO:0002250 155 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.012
cardiac muscle cell contraction GO:0086003 7 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
midgut development GO:0007494 4 0.012
paraxial mesodermal cell differentiation GO:0048342 2 0.012
regulation of t cell proliferation GO:0042129 92 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
t cell activation GO:0042110 289 0.012
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.012
positive regulation of interleukin 6 production GO:0032755 37 0.012
vitamin d3 metabolic process GO:0070640 3 0.012
kidney epithelium development GO:0072073 121 0.012
response to lipopolysaccharide GO:0032496 128 0.012
positive regulation of innate immune response GO:0045089 80 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
sodium ion export GO:0071436 2 0.012
striated muscle contraction GO:0006941 45 0.012
positive regulation of epidermis development GO:0045684 13 0.012
negative regulation of cysteine type endopeptidase activity GO:2000117 22 0.012
immune response activating signal transduction GO:0002757 116 0.012
regulation of metal ion transport GO:0010959 106 0.012
positive regulation of protein modification process GO:0031401 299 0.012
central nervous system vasculogenesis GO:0022009 3 0.012
cellular response to insulin stimulus GO:0032869 78 0.012
intermediate filament bundle assembly GO:0045110 3 0.012
actin polymerization or depolymerization GO:0008154 54 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
regulation of cell growth GO:0001558 91 0.012
organophosphate catabolic process GO:0046434 232 0.012
cellular alcohol metabolic process GO:0044107 3 0.012
cell recognition GO:0008037 83 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
peptidyl serine modification GO:0018209 83 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
cell differentiation involved in embryonic placenta development GO:0060706 26 0.011
norepinephrine transport GO:0015874 2 0.011
cellular response to inorganic substance GO:0071241 37 0.011
cell junction organization GO:0034330 77 0.011
monovalent inorganic cation homeostasis GO:0055067 33 0.011
metanephric thick ascending limb development GO:0072233 2 0.011
divalent metal ion transport GO:0070838 172 0.011
positive regulation of vasoconstriction GO:0045907 4 0.011
neuron apoptotic process GO:0051402 142 0.011
neuron neuron synaptic transmission GO:0007270 69 0.011
regulation of cell cycle GO:0051726 281 0.011
cellular lipid catabolic process GO:0044242 52 0.011
small molecule catabolic process GO:0044282 71 0.011
camera type eye development GO:0043010 266 0.011
regulation of epidermal cell differentiation GO:0045604 21 0.011
urogenital system development GO:0001655 261 0.011
negative regulation of defense response GO:0031348 77 0.011
ceramide metabolic process GO:0006672 31 0.011
macromolecule glycosylation GO:0043413 55 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
nuclear division GO:0000280 158 0.011
nucleoside metabolic process GO:0009116 246 0.011
regulation of striated muscle cell differentiation GO:0051153 81 0.011
fat cell differentiation GO:0045444 160 0.011
regulation of neuron migration GO:2001222 22 0.011
sensory system development GO:0048880 3 0.011
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.011
embryonic placenta development GO:0001892 98 0.011
negative regulation of kinase activity GO:0033673 81 0.011
divalent inorganic cation transport GO:0072511 178 0.011
cytokine biosynthetic process GO:0042089 68 0.011
positive regulation of blood pressure GO:0045777 21 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
activation of immune response GO:0002253 138 0.011
cardiac muscle contraction GO:0060048 32 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
positive regulation of hair cycle GO:0042635 7 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
vascular process in circulatory system GO:0003018 62 0.010
ear development GO:0043583 200 0.010
cellular divalent inorganic anion homeostasis GO:0072501 3 0.010
digestive tract development GO:0048565 190 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
steroid metabolic process GO:0008202 119 0.010
cellular monovalent inorganic anion homeostasis GO:0030320 4 0.010
regulation of transforming growth factor beta2 production GO:0032909 2 0.010
somatic cell dna recombination GO:0016444 51 0.010
vitamin d biosynthetic process GO:0042368 3 0.010
response to oxygen levels GO:0070482 62 0.010
purine ribonucleoside metabolic process GO:0046128 241 0.010
leukocyte differentiation GO:0002521 342 0.010
stress activated protein kinase signaling cascade GO:0031098 81 0.010
compound eye development GO:0048749 1 0.010
fat soluble vitamin biosynthetic process GO:0042362 4 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
nephron tubule development GO:0072080 84 0.010
calcium independent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016338 4 0.010
negative regulation of protein modification process GO:0031400 163 0.010
leukocyte mediated immunity GO:0002443 174 0.010
regulation of organelle organization GO:0033043 289 0.010
regulation of blood vessel size GO:0050880 56 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010
sensory perception of light stimulus GO:0050953 54 0.010
ammonia homeostasis GO:0097272 1 0.010
positive regulation of defense response GO:0031349 124 0.010

Slc46a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.013