Mus musculus

84 known processes

Tlx2

T-cell leukemia, homeobox 2

(Aliases: NCX,Tlx1l2,Tlx1l1,Enx,Hox11l1,Hox11L.1,Ncx1)

Tlx2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
forebrain development GO:0030900 302 0.860
respiratory system development GO:0060541 190 0.778
gland development GO:0048732 330 0.765
cell fate specification GO:0001708 72 0.759
Mouse
neuron fate specification GO:0048665 30 0.747
Mouse
regionalization GO:0003002 337 0.735
skeletal system development GO:0001501 356 0.691
regulation of neuron differentiation GO:0045664 281 0.687
developmental maturation GO:0021700 193 0.686
epithelial tube morphogenesis GO:0060562 303 0.682
respiratory tube development GO:0030323 167 0.669
negative regulation of cell proliferation GO:0008285 296 0.665
bmp signaling pathway GO:0030509 93 0.639
stem cell differentiation GO:0048863 268 0.633
cell fate commitment GO:0045165 210 0.625
Mouse
epidermis development GO:0008544 187 0.620
axonogenesis GO:0007409 274 0.614
telencephalon development GO:0021537 186 0.611
appendage development GO:0048736 166 0.601
Fly
endocrine system development GO:0035270 98 0.600
branching morphogenesis of an epithelial tube GO:0048754 159 0.598
embryonic organ morphogenesis GO:0048562 276 0.593
muscle tissue development GO:0060537 308 0.577
neuron migration GO:0001764 122 0.559
Mouse
embryonic skeletal system development GO:0048706 120 0.557
lung development GO:0030324 164 0.547
ear morphogenesis GO:0042471 118 0.530
cerebral cortex development GO:0021987 86 0.519
axon guidance GO:0007411 141 0.499
central nervous system neuron differentiation GO:0021953 162 0.486
germ cell development GO:0007281 185 0.486
multicellular organismal signaling GO:0035637 91 0.481
ear development GO:0043583 200 0.476
stem cell development GO:0048864 219 0.471
urogenital system development GO:0001655 261 0.447
positive regulation of nervous system development GO:0051962 221 0.433
cell maturation GO:0048469 127 0.427
heart morphogenesis GO:0003007 178 0.417
mesenchyme development GO:0060485 152 0.416
hindbrain development GO:0030902 128 0.412
pancreatic pp cell fate commitment GO:0003329 2 0.404
cellular amino acid metabolic process GO:0006520 103 0.392
blood vessel morphogenesis GO:0048514 285 0.386
stem cell maintenance GO:0019827 130 0.384
stem cell proliferation GO:0072089 117 0.376
spinal cord development GO:0021510 81 0.367
kidney development GO:0001822 213 0.364
ventral spinal cord interneuron fate commitment GO:0060579 14 0.363
sensory perception GO:0007600 245 0.355
striated muscle tissue development GO:0014706 293 0.349
neuron projection guidance GO:0097485 141 0.348
regulation of cellular amino acid metabolic process GO:0006521 5 0.341
regulation of organ morphogenesis GO:2000027 144 0.341
paraxial mesodermal cell differentiation GO:0048342 2 0.340
appendage morphogenesis GO:0035107 149 0.339
Fly
morphogenesis of a branching structure GO:0001763 203 0.325
myeloid cell differentiation GO:0030099 233 0.317
pituitary gland development GO:0021983 38 0.311
neural precursor cell proliferation GO:0061351 121 0.309
neural tube development GO:0021915 160 0.308
cellular amine metabolic process GO:0044106 44 0.294
autonomic nervous system development GO:0048483 43 0.288
ventral spinal cord development GO:0021517 48 0.288
neuromuscular process GO:0050905 99 0.286
renal tubule development GO:0061326 87 0.286
positive regulation of transcription via serum response element binding GO:0010735 1 0.285
positive regulation of cell development GO:0010720 237 0.282
somatotropin secreting cell differentiation GO:0060126 4 0.281
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.280
skeletal muscle organ development GO:0060538 163 0.280
fat cell differentiation GO:0045444 160 0.276
tube formation GO:0035148 140 0.266
skeletal system morphogenesis GO:0048705 203 0.260
neurohypophysis development GO:0021985 2 0.257
skin development GO:0043588 220 0.257
mesenchymal cell differentiation GO:0048762 107 0.257
kidney epithelium development GO:0072073 121 0.255
morphogenesis of a branching epithelium GO:0061138 193 0.252
regulation of cell cycle GO:0051726 281 0.251
Fly
lung cell differentiation GO:0060479 30 0.242
ameboidal type cell migration GO:0001667 128 0.239
regulation of vasculature development GO:1901342 88 0.239
developmental induction GO:0031128 34 0.238
cell cell signaling involved in cell fate commitment GO:0045168 35 0.233
digestive tract development GO:0048565 190 0.229
cardiac chamber morphogenesis GO:0003206 93 0.228
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.225
epithelial cell development GO:0002064 159 0.223
regulation of cellular ketone metabolic process GO:0010565 66 0.220
mesoderm development GO:0007498 100 0.214
positive regulation of programmed cell death GO:0043068 218 0.213
ventral spinal cord interneuron differentiation GO:0021514 16 0.212
cardiac pacemaker cell fate commitment GO:0060927 1 0.212
nephron morphogenesis GO:0072028 69 0.212
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.211
nephron epithelium development GO:0072009 92 0.209
epithelial tube formation GO:0072175 130 0.206
regulation of cell migration GO:0030334 219 0.205
connective tissue development GO:0061448 179 0.203
limbic system development GO:0021761 72 0.201
pallium development GO:0021543 120 0.200
embryonic epithelial tube formation GO:0001838 130 0.200
wnt signaling pathway GO:0016055 188 0.197
mesonephric epithelium development GO:0072163 94 0.195
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.192
digestive system development GO:0055123 200 0.191
regulation of organ growth GO:0046620 61 0.190
hair follicle development GO:0001942 85 0.190
hypophysis morphogenesis GO:0048850 3 0.189
ectoderm formation GO:0001705 3 0.188
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.186
determination of left right symmetry GO:0007368 80 0.186
kidney morphogenesis GO:0060993 83 0.185
formation of primary germ layer GO:0001704 77 0.184
positive regulation of glial cell differentiation GO:0045687 21 0.183
epithelial cell proliferation GO:0050673 174 0.181
cell fate determination involved in pattern specification GO:0060582 1 0.181
forebrain cell migration GO:0021885 58 0.180
regulation of cardioblast differentiation GO:0051890 3 0.178
carbohydrate derivative biosynthetic process GO:1901137 183 0.178
neural tube formation GO:0001841 108 0.178
cartilage development GO:0051216 140 0.175
nephron development GO:0072006 109 0.175
chemotaxis GO:0006935 247 0.172
leukocyte differentiation GO:0002521 342 0.172
glandular epithelial cell differentiation GO:0002067 38 0.171
ureteric bud morphogenesis GO:0060675 62 0.170
leukocyte proliferation GO:0070661 172 0.170
action potential GO:0001508 78 0.169
regulation of stem cell proliferation GO:0072091 78 0.168
mesoderm formation GO:0001707 62 0.167
regulation of secretion by cell GO:1903530 249 0.167
inner ear morphogenesis GO:0042472 101 0.167
regulation of ion transport GO:0043269 215 0.165
paraxial mesodermal cell fate commitment GO:0048343 2 0.165
cellular ketone metabolic process GO:0042180 84 0.164
positive regulation of gliogenesis GO:0014015 27 0.164
purkinje myocyte differentiation GO:0003168 1 0.164
morphogenesis of embryonic epithelium GO:0016331 159 0.163
cell differentiation in spinal cord GO:0021515 53 0.163
lung epithelium development GO:0060428 37 0.162
development of primary sexual characteristics GO:0045137 143 0.160
plasma cell differentiation GO:0002317 3 0.157
primary neural tube formation GO:0014020 95 0.157
sensory organ morphogenesis GO:0090596 242 0.156
hippocampus development GO:0021766 52 0.156
regulation of metal ion transport GO:0010959 106 0.155
molting cycle GO:0042303 90 0.153
negative regulation of nervous system development GO:0051961 156 0.152
determination of heart left right asymmetry GO:0061371 48 0.151
striated muscle cell proliferation GO:0014855 39 0.149
skeletal muscle cell differentiation GO:0035914 66 0.147
limb morphogenesis GO:0035108 149 0.147
amine metabolic process GO:0009308 45 0.147
embryonic heart tube development GO:0035050 65 0.147
nephron tubule morphogenesis GO:0072078 68 0.147
digestive tract morphogenesis GO:0048546 147 0.146
ureteric bud development GO:0001657 94 0.146
sensory perception of sound GO:0007605 97 0.146
ventral spinal cord interneuron fate determination GO:0060580 1 0.142
oogenesis GO:0048477 56 0.142
nitrogen compound transport GO:0071705 271 0.141
atrioventricular node cell development GO:0060928 2 0.141
limb development GO:0060173 166 0.140
cytoplasmic transport GO:0016482 234 0.140
cell type specific apoptotic process GO:0097285 268 0.140
axon ensheathment GO:0008366 76 0.139
regulation of fat cell differentiation GO:0045598 81 0.139
positive regulation of cardioblast differentiation GO:0051891 3 0.138
lung epithelial cell differentiation GO:0060487 29 0.137
atrioventricular node cell differentiation GO:0060922 2 0.137
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.135
b cell differentiation GO:0030183 78 0.135
cation transport GO:0006812 399 0.134
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.133
renal tubule morphogenesis GO:0061333 72 0.132
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.130
auditory receptor cell fate determination GO:0042668 3 0.129
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.129
positive regulation of epithelial cell proliferation GO:0050679 68 0.128
cardiac ventricle development GO:0003231 83 0.128
negative regulation of wnt signaling pathway GO:0030178 73 0.128
cardiac muscle tissue development GO:0048738 130 0.126
inner ear receptor cell differentiation GO:0060113 61 0.126
auditory receptor cell fate specification GO:0042667 1 0.126
embryonic heart tube morphogenesis GO:0003143 51 0.125
embryonic limb morphogenesis GO:0030326 126 0.125
regulation of body fluid levels GO:0050878 162 0.123
regulation of canonical wnt signaling pathway GO:0060828 82 0.123
hair cell differentiation GO:0035315 40 0.123
divalent inorganic cation transport GO:0072511 178 0.122
forebrain neuron differentiation GO:0021879 52 0.122
subpallium neuron fate commitment GO:0060163 2 0.121
t cell activation GO:0042110 289 0.121
regulation of glial cell differentiation GO:0045685 41 0.121
pancreatic a cell fate commitment GO:0003326 2 0.120
mesoderm morphogenesis GO:0048332 64 0.120
purine containing compound metabolic process GO:0072521 311 0.120
pancreatic pp cell differentiation GO:0003312 2 0.119
oligodendrocyte differentiation GO:0048709 53 0.118
regulation of neuron projection development GO:0010975 169 0.118
mesodermal cell differentiation GO:0048333 22 0.117
neuron fate determination GO:0048664 9 0.117
atrial cardiac muscle cell development GO:0055014 2 0.117
translation GO:0006412 93 0.116
glial cell differentiation GO:0010001 131 0.116
segmentation GO:0035282 93 0.115
protein localization to nucleus GO:0034504 121 0.113
outflow tract morphogenesis GO:0003151 53 0.112
mesonephric tubule development GO:0072164 94 0.112
carbohydrate metabolic process GO:0005975 230 0.112
placenta development GO:0001890 140 0.111
cerebral cortex cell migration GO:0021795 44 0.109
regulation of cell motility GO:2000145 236 0.109
camera type eye development GO:0043010 266 0.108
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.108
regulation of gliogenesis GO:0014013 50 0.107
immune effector process GO:0002252 321 0.106
globus pallidus development GO:0021759 2 0.106
menarche GO:0042696 1 0.106
notch signaling pathway GO:0007219 71 0.105
Fly
regulation of myeloid cell differentiation GO:0045637 96 0.104
glial cell fate commitment GO:0021781 14 0.104
hair cycle GO:0042633 90 0.103
mechanoreceptor differentiation GO:0042490 67 0.103
male gamete generation GO:0048232 285 0.102
locomotory behavior GO:0007626 195 0.102
nephron tubule development GO:0072080 84 0.102
regulation of anagen GO:0051884 1 0.102
metal ion homeostasis GO:0055065 189 0.101
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.101
neural crest cell development GO:0014032 48 0.101
mesenchymal cell development GO:0014031 93 0.100
epithalamus development GO:0021538 2 0.100
divalent metal ion transport GO:0070838 172 0.100
spermatogenesis GO:0007283 284 0.099
adenohypophysis development GO:0021984 14 0.099
myeloid cell homeostasis GO:0002262 114 0.099
regulation of kidney development GO:0090183 40 0.099
auditory receptor cell differentiation GO:0042491 37 0.099
response to growth factor GO:0070848 198 0.099
regulation of wnt signaling pathway GO:0030111 123 0.098
muscle cell differentiation GO:0042692 261 0.097
atrioventricular node cell fate commitment GO:0060929 1 0.097
regulation of auditory receptor cell differentiation GO:0045607 4 0.097
regulation of bmp signaling pathway GO:0030510 60 0.097
midbrain development GO:0030901 35 0.097
erythrocyte differentiation GO:0030218 88 0.096
neuroblast proliferation GO:0007405 49 0.096
lymphocyte differentiation GO:0030098 242 0.096
gastrulation GO:0007369 116 0.095
regulation of muscle tissue development GO:1901861 97 0.095
atrial cardiac muscle cell differentiation GO:0055011 2 0.095
angiogenesis GO:0001525 201 0.095
metanephros development GO:0001656 79 0.095
spinal cord dorsal ventral patterning GO:0021513 23 0.094
cation homeostasis GO:0055080 212 0.093
sensory system development GO:0048880 3 0.093
membrane organization GO:0061024 245 0.092
spinal cord patterning GO:0021511 25 0.092
regulation of cardiac muscle cell proliferation GO:0060043 23 0.091
metanephric macula densa development GO:0072227 1 0.090
tube closure GO:0060606 91 0.090
regulation of stem cell differentiation GO:2000736 50 0.090
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.090
blastocyst development GO:0001824 80 0.090
cranial nerve development GO:0021545 41 0.090
wound healing GO:0042060 157 0.089
cell fate commitment involved in pattern specification GO:0060581 14 0.089
cell differentiation in hindbrain GO:0021533 24 0.089
male gonad development GO:0008584 88 0.088
muscle cell development GO:0055001 133 0.088
regulation of secretion GO:0051046 274 0.088
ossification GO:0001503 216 0.087
rhythmic process GO:0048511 174 0.087
peptidyl amino acid modification GO:0018193 336 0.085
developmental programmed cell death GO:0010623 41 0.085
calcium ion transport GO:0006816 159 0.085
telencephalon cell migration GO:0022029 55 0.085
apoptotic process involved in morphogenesis GO:0060561 25 0.085
cardiocyte differentiation GO:0035051 87 0.084
embryonic skeletal system morphogenesis GO:0048704 91 0.084
nucleoside phosphate metabolic process GO:0006753 338 0.083
canonical wnt signaling pathway GO:0060070 130 0.083
diencephalon development GO:0021536 63 0.082
somitogenesis GO:0001756 69 0.082
establishment of organ orientation GO:0048561 1 0.082
lung secretory cell differentiation GO:0061140 13 0.082
anatomical structure homeostasis GO:0060249 145 0.082
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.082
myeloid leukocyte differentiation GO:0002573 119 0.081
neural tube closure GO:0001843 90 0.081
sensory perception of mechanical stimulus GO:0050954 107 0.081
muscle system process GO:0003012 141 0.081
central nervous system vasculogenesis GO:0022009 3 0.080
regulation of neural precursor cell proliferation GO:2000177 70 0.080
tissue remodeling GO:0048771 102 0.080
branching involved in ureteric bud morphogenesis GO:0001658 56 0.080
neuronal action potential GO:0019228 54 0.080
motor neuron axon guidance GO:0008045 26 0.080
compound eye development GO:0048749 1 0.079
cytosolic calcium ion homeostasis GO:0051480 70 0.079
regulation of epidermis development GO:0045682 33 0.078
regulation of retina development in camera type eye GO:1902866 3 0.078
gliogenesis GO:0042063 141 0.078
oligodendrocyte development GO:0014003 20 0.076
retina development in camera type eye GO:0060041 119 0.076
positive regulation of neuron differentiation GO:0045666 141 0.076
oocyte development GO:0048599 33 0.075
neural crest cell differentiation GO:0014033 54 0.075
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.075
endomembrane system organization GO:0010256 147 0.074
mammary gland morphogenesis GO:0060443 54 0.074
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.074
smoothened signaling pathway GO:0007224 105 0.074
g protein coupled receptor signaling pathway GO:0007186 243 0.073
muscle cell proliferation GO:0033002 52 0.073
ovulation cycle GO:0042698 59 0.072
positive regulation of stem cell proliferation GO:2000648 59 0.072
regulation of organ formation GO:0003156 34 0.072
lung morphogenesis GO:0060425 50 0.072
brain segmentation GO:0035284 3 0.071
nephron epithelium morphogenesis GO:0072088 68 0.071
metanephric dct cell differentiation GO:0072240 3 0.071
heart formation GO:0060914 16 0.071
pulmonary myocardium development GO:0003350 3 0.071
postganglionic parasympathetic nervous system development GO:0021784 2 0.071
skin morphogenesis GO:0043589 38 0.071
nucleocytoplasmic transport GO:0006913 139 0.071
regulation of epithelial cell proliferation GO:0050678 141 0.071
maintenance of location GO:0051235 89 0.070
cellular response to growth factor stimulus GO:0071363 197 0.070
thymus development GO:0048538 41 0.070
organ growth GO:0035265 117 0.070
paramesonephric duct development GO:0061205 3 0.069
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.068
kidney mesenchyme development GO:0072074 14 0.067
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.067
regulation of transcription involved in cell fate commitment GO:0060850 15 0.066
artery development GO:0060840 53 0.066
female gamete generation GO:0007292 74 0.066
regulation of neural retina development GO:0061074 3 0.066
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.065
regulation of membrane potential GO:0042391 192 0.065
development of primary male sexual characteristics GO:0046546 88 0.065
oocyte differentiation GO:0009994 35 0.065
sensory organ boundary specification GO:0008052 1 0.064
type b pancreatic cell fate commitment GO:0003327 1 0.064
cardiac chamber development GO:0003205 108 0.064
oocyte maturation GO:0001556 18 0.064
pyramidal neuron migration GO:0021852 1 0.064
mesonephric tubule morphogenesis GO:0072171 63 0.064
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.064
t cell proliferation GO:0042098 120 0.064
hindbrain formation GO:0021576 1 0.063
regulation of apoptotic signaling pathway GO:2001233 197 0.063
regulation of protein localization GO:0032880 231 0.063
divalent inorganic cation homeostasis GO:0072507 138 0.063
neuromuscular process controlling balance GO:0050885 59 0.063
regulation of adaptive immune response GO:0002819 90 0.062
developmental growth involved in morphogenesis GO:0060560 138 0.062
Fly
epidermis morphogenesis GO:0048730 33 0.062
detection of monosaccharide stimulus GO:0034287 1 0.062
metanephros morphogenesis GO:0003338 24 0.061
transmission of nerve impulse GO:0019226 76 0.061
prostate gland stromal morphogenesis GO:0060741 2 0.061
neuroblast differentiation GO:0014016 2 0.061
female sex differentiation GO:0046660 84 0.060
embryonic appendage morphogenesis GO:0035113 126 0.060
glycosyl compound catabolic process GO:1901658 206 0.060
intracellular protein transport GO:0006886 204 0.060
regulation of morphogenesis of a branching structure GO:0060688 53 0.060
protein import GO:0017038 101 0.059
metanephric nephron morphogenesis GO:0072273 19 0.059
forebrain morphogenesis GO:0048853 17 0.059
palate development GO:0060021 76 0.059
nuclear transport GO:0051169 139 0.058
asymmetric stem cell division GO:0098722 3 0.058
renal vesicle induction GO:0072034 3 0.058
male sex differentiation GO:0046661 109 0.058
protein localization to organelle GO:0033365 185 0.058
inner cell mass cell fate commitment GO:0001827 2 0.058
clara cell differentiation GO:0060486 4 0.057
cardiac septum development GO:0003279 59 0.057
cell fate determination GO:0001709 32 0.057
cell differentiation involved in kidney development GO:0061005 33 0.057
regulation of cellular amine metabolic process GO:0033238 20 0.056
gonad development GO:0008406 141 0.056
spinal cord motor neuron differentiation GO:0021522 35 0.056
myelination GO:0042552 74 0.056
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.055
lung field specification GO:0060424 3 0.055
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.055
metanephric nephron tubule development GO:0072234 16 0.055
positive regulation of stem cell differentiation GO:2000738 23 0.055
multicellular organism growth GO:0035264 161 0.054
regulation of lymphocyte proliferation GO:0050670 117 0.054
mesenchyme morphogenesis GO:0072132 32 0.054
astrocyte fate commitment GO:0060018 4 0.054
positive regulation of growth GO:0045927 104 0.054
specification of organ identity GO:0010092 30 0.054
positive regulation of behavior GO:0048520 40 0.054
cell division GO:0051301 120 0.054
embryonic digit morphogenesis GO:0042733 56 0.054
cellular divalent inorganic cation homeostasis GO:0072503 127 0.054
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.053
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.053
synapse organization GO:0050808 125 0.053
hormone secretion GO:0046879 128 0.053
lymphocyte homeostasis GO:0002260 64 0.052
ventricular cardiac myofibril assembly GO:0055005 3 0.052
asymmetric neuroblast division GO:0055059 1 0.052
olfactory lobe development GO:0021988 32 0.051
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.051
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.051
midbrain hindbrain boundary maturation GO:0021732 1 0.051
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.051
olfactory bulb development GO:0021772 30 0.051
forebrain generation of neurons GO:0021872 63 0.051
positive regulation of cell cycle GO:0045787 92 0.051
regulation of angiogenesis GO:0045765 81 0.051
lung induction GO:0060492 3 0.050
renal system development GO:0072001 225 0.050
dendrite development GO:0016358 115 0.050
hormone metabolic process GO:0042445 86 0.049
purine ribonucleotide metabolic process GO:0009150 290 0.049
regulation of protein transport GO:0051223 163 0.049
cell proliferation in forebrain GO:0021846 30 0.049
chondrocyte differentiation GO:0002062 72 0.049
septum transversum development GO:0003343 2 0.049
endoderm development GO:0007492 45 0.048
regulation of system process GO:0044057 200 0.048
Mouse
epithelial cell fate commitment GO:0072148 13 0.048
odontogenesis GO:0042476 78 0.048
brain morphogenesis GO:0048854 32 0.048
spemann organizer formation GO:0060061 2 0.048
positive regulation of protein phosphorylation GO:0001934 242 0.047
bronchiole development GO:0060435 3 0.047
regulation of cell activation GO:0050865 289 0.047
renal inner medulla development GO:0072053 3 0.047
regulation of mesenchymal cell proliferation GO:0010464 37 0.047
regulation of establishment of protein localization GO:0070201 181 0.047
glossopharyngeal nerve morphogenesis GO:0021615 4 0.047
heart growth GO:0060419 45 0.047
neuroepithelial cell differentiation GO:0060563 37 0.046
microtubule based process GO:0007017 236 0.046
cellular homeostasis GO:0019725 240 0.046
negative regulation of intracellular signal transduction GO:1902532 167 0.046
cellular metal ion homeostasis GO:0006875 151 0.046
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.045
cerebellum formation GO:0021588 1 0.045
lens development in camera type eye GO:0002088 62 0.045
positive regulation of angiogenesis GO:0045766 46 0.045
positive regulation of cell migration GO:0030335 109 0.045
heart contraction GO:0060047 93 0.045
parasympathetic nervous system development GO:0048486 19 0.045
response to organonitrogen compound GO:0010243 246 0.044
homeostasis of number of cells GO:0048872 210 0.044
inner medullary collecting duct development GO:0072061 2 0.044
cerebral cortex radially oriented cell migration GO:0021799 31 0.043
sympathetic nervous system development GO:0048485 22 0.043
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.043
metencephalon development GO:0022037 89 0.043
cellular chemical homeostasis GO:0055082 215 0.043
regulation of organelle organization GO:0033043 289 0.043
positive regulation of kidney development GO:0090184 28 0.043
middle ear morphogenesis GO:0042474 23 0.043
regulation of translation GO:0006417 71 0.043
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.042
mesonephros development GO:0001823 97 0.042
regulation of binding GO:0051098 111 0.042
trachea cartilage morphogenesis GO:0060535 4 0.042
regulation of transmembrane transport GO:0034762 128 0.042
spemann organizer formation at the anterior end of the primitive streak GO:0060064 1 0.042
striated muscle cell development GO:0055002 125 0.042
metanephric loop of henle development GO:0072236 4 0.042
endodermal cell fate specification GO:0001714 4 0.042
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.042
apoptotic signaling pathway GO:0097190 306 0.041
ensheathment of neurons GO:0007272 76 0.041
regulation of ion transmembrane transport GO:0034765 119 0.041
astrocyte differentiation GO:0048708 43 0.041
cardiac ventricle morphogenesis GO:0003208 50 0.041
nerve development GO:0021675 67 0.041
ras protein signal transduction GO:0007265 77 0.041
pigmentation GO:0043473 71 0.040
proprioception GO:0019230 4 0.040
phenol containing compound metabolic process GO:0018958 60 0.040
purine nucleoside triphosphate metabolic process GO:0009144 226 0.040
posttranscriptional regulation of gene expression GO:0010608 155 0.040
somite development GO:0061053 81 0.040
b cell activation GO:0042113 161 0.040
hair follicle morphogenesis GO:0031069 29 0.040
positive regulation of transcription by glucose GO:0046016 3 0.040
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.039
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.039
ventricular cardiac muscle tissue development GO:0003229 38 0.039
positive regulation of bmp signaling pathway GO:0030513 23 0.039

Tlx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039