Mus musculus

120 known processes

Brsk2

BR serine/threonine kinase 2

(Aliases: SADA,4833424K13Rik,SAD-A)

Brsk2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synapse organization GO:0050808 125 0.346
Worm
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.252
Worm
establishment of synaptic vesicle localization GO:0097480 57 0.223
Worm
microtubule cytoskeleton organization GO:0000226 157 0.221
Mouse
synaptic transmission GO:0007268 329 0.200
Worm
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.177
axonogenesis GO:0007409 274 0.171
conditioned taste aversion GO:0001661 4 0.158
establishment of vesicle localization GO:0051650 81 0.144
Worm
synaptic vesicle transport GO:0048489 57 0.126
Worm
regulation of neuron differentiation GO:0045664 281 0.122
Worm
cognition GO:0050890 149 0.121
regulation of feeding behavior GO:0060259 3 0.119
regulation of neuron projection development GO:0010975 169 0.116
Worm
establishment of organelle localization GO:0051656 122 0.103
Worm
sperm motility GO:0030317 47 0.096
neuron projection extension GO:1990138 64 0.094
Worm
spermatogenesis GO:0007283 284 0.086
peptide transport GO:0015833 133 0.085
dendrite development GO:0016358 115 0.084
male gamete generation GO:0048232 285 0.081
regulation of hormone secretion GO:0046883 88 0.081
synapse assembly GO:0007416 56 0.078
Worm
regulation of cellular component size GO:0032535 121 0.077
Worm
locomotory behavior GO:0007626 195 0.070
regulation of cell projection organization GO:0031344 206 0.069
Worm
vesicle localization GO:0051648 86 0.067
Worm
sensory perception GO:0007600 245 0.067
peptidyl serine modification GO:0018209 83 0.067
positive regulation of protein modification process GO:0031401 299 0.066
single organism cell adhesion GO:0098602 156 0.065
regulation of postsynaptic membrane potential GO:0060078 48 0.064
spermatid differentiation GO:0048515 115 0.063
organelle localization GO:0051640 179 0.062
Worm
learning or memory GO:0007611 148 0.058
nitrogen compound transport GO:0071705 271 0.057
hormone secretion GO:0046879 128 0.057
germ cell development GO:0007281 185 0.057
ion transmembrane transport GO:0034220 361 0.056
regulation of cellular component biogenesis GO:0044087 181 0.055
regulation of peptide hormone secretion GO:0090276 75 0.054
carbohydrate homeostasis GO:0033500 128 0.053
maternal determination of anterior posterior axis embryo GO:0008358 2 0.053
sensory perception of sound GO:0007605 97 0.048
cation transport GO:0006812 399 0.048
wnt signaling pathway GO:0016055 188 0.046
microtubule based process GO:0007017 236 0.042
Mouse Worm
spermatid development GO:0007286 108 0.042
regulation of cell size GO:0008361 72 0.042
Worm
positive regulation of dopamine secretion GO:0033603 2 0.041
nuclear division GO:0000280 158 0.040
regulation of transporter activity GO:0032409 57 0.040
glucose homeostasis GO:0042593 128 0.040
regulation of voltage gated calcium channel activity GO:1901385 4 0.040
regulation of transferase activity GO:0051338 263 0.039
positive regulation of cilium movement GO:0003353 1 0.039
ribose phosphate metabolic process GO:0019693 291 0.039
multicellular organism growth GO:0035264 161 0.038
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.038
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure GO:0001988 1 0.038
learning GO:0007612 98 0.038
regulation of protein kinase activity GO:0045859 232 0.038
divalent inorganic cation transport GO:0072511 178 0.037
neurotransmitter secretion GO:0007269 62 0.036
axon cargo transport GO:0008088 33 0.035
Worm
cell adhesion GO:0007155 329 0.035
amide transport GO:0042886 138 0.035
embryonic organ morphogenesis GO:0048562 276 0.035
peptidyl serine phosphorylation GO:0018105 74 0.035
microtubule based transport GO:0010970 50 0.035
Worm
developmental growth involved in morphogenesis GO:0060560 138 0.034
Worm
peptide hormone secretion GO:0030072 109 0.034
insulin secretion GO:0030073 89 0.034
inorganic ion transmembrane transport GO:0098660 234 0.034
purine ribonucleoside metabolic process GO:0046128 241 0.033
calcium ion transmembrane transport GO:0070588 85 0.033
organelle fission GO:0048285 170 0.032
regulation of peptide transport GO:0090087 91 0.032
lateral inhibition GO:0046331 1 0.032
somatotropin secreting cell differentiation GO:0060126 4 0.032
regulation of wnt signaling pathway GO:0030111 123 0.032
regulation of membrane potential GO:0042391 192 0.032
rna splicing GO:0008380 54 0.032
stem cell differentiation GO:0048863 268 0.031
regulation of transmembrane transport GO:0034762 128 0.031
adult behavior GO:0030534 135 0.031
positive regulation of growth GO:0045927 104 0.031
regulation of anatomical structure size GO:0090066 178 0.030
Worm
cell maturation GO:0048469 127 0.030
regulation of ion transport GO:0043269 215 0.030
protein localization to organelle GO:0033365 185 0.030
neurotransmitter transport GO:0006836 76 0.030
defecation GO:0030421 1 0.030
skeletal muscle organ development GO:0060538 163 0.029
cartilage development GO:0051216 140 0.029
telencephalon development GO:0021537 186 0.029
microtubule organizing center organization GO:0031023 28 0.029
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.028
regulation of secretion GO:0051046 274 0.028
regulation of cellular ketone metabolic process GO:0010565 66 0.028
regulation of kinase activity GO:0043549 249 0.028
membrane organization GO:0061024 245 0.028
cellular ketone metabolic process GO:0042180 84 0.028
cell fate commitment GO:0045165 210 0.028
regulation of neurotransmitter levels GO:0001505 87 0.028
cytoplasmic transport GO:0016482 234 0.028
sensory perception of mechanical stimulus GO:0050954 107 0.027
neuron neuron synaptic transmission GO:0007270 69 0.027
response to light stimulus GO:0009416 135 0.027
positive regulation of mapk cascade GO:0043410 170 0.027
pole plasm assembly GO:0007315 2 0.027
regulation of homeostatic process GO:0032844 182 0.027
histone modification GO:0016570 159 0.027
nucleotide metabolic process GO:0009117 332 0.027
cell growth GO:0016049 130 0.027
Worm
organelle assembly GO:0070925 177 0.027
macromolecule catabolic process GO:0009057 281 0.026
cellular response to monosaccharide stimulus GO:0071326 47 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
gland development GO:0048732 330 0.026
regulation of extent of cell growth GO:0061387 52 0.026
Worm
circadian sleep wake cycle non rem sleep GO:0042748 2 0.025
meiotic cell cycle process GO:1903046 77 0.025
establishment or maintenance of cell polarity GO:0007163 86 0.025
female gamete generation GO:0007292 74 0.025
circadian sleep wake cycle rem sleep GO:0042747 1 0.025
positive regulation of transferase activity GO:0051347 167 0.025
generation of ovulation cycle rhythm GO:0060112 1 0.025
positive regulation of protein phosphorylation GO:0001934 242 0.025
intracellular mrna localization GO:0008298 4 0.024
amine metabolic process GO:0009308 45 0.024
regulation of organelle organization GO:0033043 289 0.024
divalent metal ion transport GO:0070838 172 0.024
acetylcholine transport GO:0015870 2 0.024
endomembrane system organization GO:0010256 147 0.024
intracellular protein transport GO:0006886 204 0.024
response to radiation GO:0009314 165 0.024
compound eye development GO:0048749 1 0.023
positive regulation of hydrolase activity GO:0051345 148 0.023
regulation of hormone levels GO:0010817 211 0.023
cilium movement GO:0003341 28 0.023
positive regulation of secretion by cell GO:1903532 114 0.023
transmembrane transport GO:0055085 412 0.023
cellular response to dna damage stimulus GO:0006974 207 0.023
chromatin organization GO:0006325 206 0.023
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.022
regulation of secretion by cell GO:1903530 249 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
cellular homeostasis GO:0019725 240 0.022
oocyte construction GO:0007308 2 0.022
mapk cascade GO:0000165 281 0.022
hindbrain development GO:0030902 128 0.022
positive regulation of protein kinase activity GO:0045860 144 0.022
inorganic cation transmembrane transport GO:0098662 207 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
purine nucleoside triphosphate catabolic process GO:0009146 203 0.022
cation transmembrane transport GO:0098655 266 0.022
synaptic transmission involved in micturition GO:0060084 3 0.021
positive regulation of kinase activity GO:0033674 155 0.021
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.021
sensory organ morphogenesis GO:0090596 242 0.021
memory GO:0007613 58 0.021
forebrain development GO:0030900 302 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
inter male aggressive behavior GO:0002121 3 0.020
negative regulation of molecular function GO:0044092 258 0.020
meiosis i GO:0007127 60 0.020
t cell activation GO:0042110 289 0.020
regionalization GO:0003002 337 0.020
regulation of circadian rhythm GO:0042752 58 0.020
ras protein signal transduction GO:0007265 77 0.020
microtubule based movement GO:0007018 84 0.020
Worm
developmental maturation GO:0021700 193 0.020
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.020
establishment of protein localization to organelle GO:0072594 118 0.020
regulation of cell cycle GO:0051726 281 0.019
lipid localization GO:0010876 126 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
oocyte anterior posterior axis specification GO:0007314 2 0.019
positive regulation of cell development GO:0010720 237 0.019
cell cycle checkpoint GO:0000075 47 0.019
regulation of purine nucleotide metabolic process GO:1900542 169 0.019
detection of stimulus GO:0051606 84 0.019
synaptic transmission cholinergic GO:0007271 7 0.019
myotube differentiation GO:0014902 105 0.019
regulation of reproductive process GO:2000241 66 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
apoptotic signaling pathway GO:0097190 306 0.019
Human
rhythmic process GO:0048511 174 0.019
regulation of hydrolase activity GO:0051336 246 0.018
regulation of microtubule based process GO:0032886 52 0.018
sodium ion transmembrane transport GO:0035725 49 0.018
oocyte axis specification GO:0007309 2 0.018
regulation of rna splicing GO:0043484 37 0.018
positive regulation of secretion GO:0051047 130 0.018
covalent chromatin modification GO:0016569 163 0.018
nucleoside catabolic process GO:0009164 206 0.018
inner ear morphogenesis GO:0042472 101 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
centrosome cycle GO:0007098 23 0.018
Mouse
meiotic nuclear division GO:0007126 115 0.018
lipid transport GO:0006869 98 0.018
sensory perception of light stimulus GO:0050953 54 0.018
lateral geniculate nucleus development GO:0021771 1 0.018
mrna processing GO:0006397 63 0.018
axon guidance GO:0007411 141 0.018
Worm
negative regulation of membrane potential GO:0045837 4 0.018
regulation of cell growth GO:0001558 91 0.017
Worm
nucleoside metabolic process GO:0009116 246 0.017
cellular amine metabolic process GO:0044106 44 0.017
regulation of dopamine secretion GO:0014059 9 0.017
regulation of circadian sleep wake cycle non rem sleep GO:0045188 1 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
regulation of neuronal synaptic plasticity GO:0048168 30 0.017
regulation of muscle contraction GO:0006937 49 0.017
diencephalon development GO:0021536 63 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
norepinephrine transport GO:0015874 2 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
baroreceptor response to decreased systemic arterial blood pressure GO:0001982 2 0.017
tube formation GO:0035148 140 0.017
skeletal system development GO:0001501 356 0.017
regulation of cytokine production GO:0001817 266 0.016
regulation of synaptic plasticity GO:0048167 87 0.016
positive regulation of ion transport GO:0043270 65 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
cellularization GO:0007349 1 0.016
carbohydrate metabolic process GO:0005975 230 0.016
myeloid cell differentiation GO:0030099 233 0.016
positive regulation of organelle organization GO:0010638 128 0.016
meiotic cell cycle GO:0051321 122 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
response to organonitrogen compound GO:0010243 246 0.016
muscle tissue development GO:0060537 308 0.016
glial cell differentiation GO:0010001 131 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
calcium ion transport GO:0006816 159 0.016
canonical wnt signaling pathway GO:0060070 130 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
regulation of ion transmembrane transporter activity GO:0032412 54 0.015
regulation of protein catabolic process GO:0042176 108 0.015
regulation of norepinephrine secretion GO:0014061 2 0.015
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.015
dna metabolic process GO:0006259 303 0.015
cytoskeleton dependent intracellular transport GO:0030705 50 0.015
Worm
regulation of synapse assembly GO:0051963 29 0.015
digestive system development GO:0055123 200 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
skin development GO:0043588 220 0.015
exocytosis GO:0006887 121 0.015
rna processing GO:0006396 105 0.015
nucleoside phosphate metabolic process GO:0006753 338 0.015
lymphocyte proliferation GO:0046651 164 0.015
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.015
central nervous system neuron differentiation GO:0021953 162 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.015
epithelial tube formation GO:0072175 130 0.015
muscle cell differentiation GO:0042692 261 0.015
cellular glucose homeostasis GO:0001678 52 0.015
regulation of protein localization GO:0032880 231 0.015
guanosine containing compound catabolic process GO:1901069 144 0.015
muscle contraction GO:0006936 101 0.015
feeding behavior GO:0007631 62 0.015
associative learning GO:0008306 61 0.015
spinal cord development GO:0021510 81 0.015
organophosphate catabolic process GO:0046434 232 0.015
heterocycle catabolic process GO:0046700 280 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.015
protein targeting GO:0006605 143 0.015
nucleotide biosynthetic process GO:0009165 78 0.015
axoneme assembly GO:0035082 15 0.014
oocyte development GO:0048599 33 0.014
sensory system development GO:0048880 3 0.014
guanosine containing compound metabolic process GO:1901068 144 0.014
endocytosis GO:0006897 168 0.014
negative regulation of organelle organization GO:0010639 90 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
negative regulation of action potential GO:0045759 1 0.014
negative regulation of wnt signaling pathway GO:0030178 73 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
regulation of fat cell differentiation GO:0045598 81 0.014
epithelial cell development GO:0002064 159 0.014
dna integrity checkpoint GO:0031570 28 0.014
regulation of multi organism process GO:0043900 111 0.014
heart process GO:0003015 94 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
formation of organ boundary GO:0010160 1 0.014
centrosome organization GO:0051297 26 0.014
Mouse
peptide secretion GO:0002790 114 0.014
regulation of mrna metabolic process GO:1903311 43 0.014
glutamate receptor signaling pathway GO:0007215 35 0.014
maintenance of location GO:0051235 89 0.014
protein import GO:0017038 101 0.014
ear development GO:0043583 200 0.014
neural nucleus development GO:0048857 22 0.014
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
mechanoreceptor differentiation GO:0042490 67 0.014
regulation of cell cycle process GO:0010564 160 0.014
mitotic cell cycle process GO:1903047 159 0.014
Human
protein localization to membrane GO:0072657 108 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.013
fatty acid metabolic process GO:0006631 121 0.013
lateral line system development GO:0048925 1 0.013
positive regulation of catecholamine secretion GO:0033605 2 0.013
regulation of cellular amino acid metabolic process GO:0006521 5 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
positive regulation of cellular amine metabolic process GO:0033240 5 0.013
excretion GO:0007588 22 0.013
nerve development GO:0021675 67 0.013
digestive tract development GO:0048565 190 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
telencephalon cell migration GO:0022029 55 0.013
terminal button organization GO:0072553 3 0.013
stem cell maintenance GO:0019827 130 0.013
cytokine production GO:0001816 319 0.013
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.013
acetylcholine secretion neurotransmission GO:0014055 2 0.013
rna splicing via transesterification reactions GO:0000375 43 0.013
aromatic compound catabolic process GO:0019439 286 0.013
regulation of cell adhesion GO:0030155 154 0.013
nucleotide catabolic process GO:0009166 217 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
cellular response to carbohydrate stimulus GO:0071322 50 0.013
protein catabolic process GO:0030163 221 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
hindbrain morphogenesis GO:0021575 46 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
dopamine uptake involved in synaptic transmission GO:0051583 4 0.012
regulation of system process GO:0044057 200 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
retina development in camera type eye GO:0060041 119 0.012
response to monosaccharide GO:0034284 67 0.012
gtp catabolic process GO:0006184 143 0.012
leukocyte proliferation GO:0070661 172 0.012
oxidation reduction process GO:0055114 342 0.012
ear morphogenesis GO:0042471 118 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
regulation of translation GO:0006417 71 0.012
chromatin modification GO:0016568 187 0.012
neural tube formation GO:0001841 108 0.012
regulation of mapk cascade GO:0043408 248 0.012
negative regulation of camp mediated signaling GO:0043951 3 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
development of primary sexual characteristics GO:0045137 143 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
cerebellar cortex morphogenesis GO:0021696 32 0.012
cellular protein complex assembly GO:0043623 116 0.012
rap protein signal transduction GO:0032486 3 0.012
digestive tract morphogenesis GO:0048546 147 0.012
organic anion transport GO:0015711 137 0.012
exploration behavior GO:0035640 21 0.012
sulfur compound metabolic process GO:0006790 100 0.012
circadian rhythm GO:0007623 114 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
neuromuscular synaptic transmission GO:0007274 16 0.012
lung development GO:0030324 164 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
cellular response to glucose stimulus GO:0071333 45 0.012
response to oxygen levels GO:0070482 62 0.012
protein oligomerization GO:0051259 67 0.012
oocyte differentiation GO:0009994 35 0.012
synaptic transmission glutamatergic GO:0035249 36 0.012
mrna splicing via spliceosome GO:0000398 43 0.011
cilium morphogenesis GO:0060271 102 0.011
adiponectin secretion GO:0070162 2 0.011
cerebellar cortex development GO:0021695 48 0.011
cerebellum development GO:0021549 77 0.011
norepinephrine secretion GO:0048243 2 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
regulation of myeloid cell differentiation GO:0045637 96 0.011
cell cell adhesion GO:0098609 41 0.011
positive regulation of cell cycle GO:0045787 92 0.011
negative regulation of protein modification process GO:0031400 163 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
mesoderm development GO:0007498 100 0.011
cellular protein catabolic process GO:0044257 155 0.011
response to acid chemical GO:0001101 111 0.011
neuromuscular process GO:0050905 99 0.011
cellular nitrogen compound catabolic process GO:0044270 280 0.011
cell substrate adhesion GO:0031589 130 0.011
gastrulation GO:0007369 116 0.011
neuron migration GO:0001764 122 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
acetate ester transport GO:1901374 2 0.011
synaptic vesicle localization GO:0097479 59 0.011
Worm
nucleocytoplasmic transport GO:0006913 139 0.011
localization within membrane GO:0051668 4 0.011
intraspecies interaction between organisms GO:0051703 21 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
regulation of glutamate receptor signaling pathway GO:1900449 16 0.011
homeostasis of number of cells GO:0048872 210 0.011
regulation of protein transport GO:0051223 163 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
negative regulation of cell cycle GO:0045786 123 0.011
activation of mapk activity GO:0000187 59 0.011
mrna metabolic process GO:0016071 84 0.011
gene silencing GO:0016458 38 0.011
negative regulation of cell development GO:0010721 169 0.011
sensory perception of pain GO:0019233 47 0.011
pancreatic pp cell differentiation GO:0003312 2 0.011
cell cell junction organization GO:0045216 72 0.011
substantia nigra development GO:0021762 2 0.011
immune effector process GO:0002252 321 0.010
renal system development GO:0072001 225 0.010
cerebral cortex neuron differentiation GO:0021895 19 0.010
membrane depolarization GO:0051899 64 0.010
smooth muscle contraction GO:0006939 44 0.010
gonad morphogenesis GO:0035262 1 0.010
neural tube development GO:0021915 160 0.010
positive regulation of interleukin 1 alpha production GO:0032730 4 0.010
social behavior GO:0035176 21 0.010
cyclic nucleotide metabolic process GO:0009187 59 0.010
forebrain generation of neurons GO:0021872 63 0.010
protein ubiquitination GO:0016567 171 0.010
ribonucleoprotein complex subunit organization GO:0071826 28 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
regulation of protein complex assembly GO:0043254 83 0.010
mesodermal cell migration GO:0008078 4 0.010

Brsk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.013
disease of anatomical entity DOID:7 0 0.013
disease of mental health DOID:150 0 0.010