Mus musculus

61 known processes

Brsk1

BR serine/threonine kinase 1

(Aliases: SAD-B,SADB,Gm1100,MGC99905)

Brsk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axon cargo transport GO:0008088 33 0.129
Worm
microtubule based transport GO:0010970 50 0.110
Worm
regulation of neuron projection development GO:0010975 169 0.097
Worm
regulation of cell projection organization GO:0031344 206 0.097
Worm
cytoskeleton dependent intracellular transport GO:0030705 50 0.086
Worm
peptide transport GO:0015833 133 0.086
Mouse
glucose homeostasis GO:0042593 128 0.083
Mouse
synaptic transmission GO:0007268 329 0.082
Worm
regulation of neuron differentiation GO:0045664 281 0.081
Worm
hormone secretion GO:0046879 128 0.080
Mouse
cell adhesion GO:0007155 329 0.075
peptidyl serine modification GO:0018209 83 0.073
Mouse Worm
response to endoplasmic reticulum stress GO:0034976 53 0.071
establishment of organelle localization GO:0051656 122 0.066
Worm
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.065
amine metabolic process GO:0009308 45 0.065
organelle localization GO:0051640 179 0.057
Worm
chemotaxis GO:0006935 247 0.056
Worm
single organism cell adhesion GO:0098602 156 0.054
insulin secretion GO:0030073 89 0.053
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.052
regulation of cellular ketone metabolic process GO:0010565 66 0.047
nitrogen compound transport GO:0071705 271 0.047
Mouse
amide transport GO:0042886 138 0.046
Mouse
establishment of vesicle localization GO:0051650 81 0.046
Worm
regulation of homeostatic process GO:0032844 182 0.044
Mouse
actin cytoskeleton organization GO:0030036 220 0.043
ribose phosphate metabolic process GO:0019693 291 0.042
synapse organization GO:0050808 125 0.042
Worm
regulation of hormone levels GO:0010817 211 0.041
Mouse
regulation of kinase activity GO:0043549 249 0.041
axonogenesis GO:0007409 274 0.040
cellular ketone metabolic process GO:0042180 84 0.039
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.039
Worm
cellular amino acid metabolic process GO:0006520 103 0.037
regulation of peptide hormone secretion GO:0090276 75 0.037
Mouse
regulation of membrane potential GO:0042391 192 0.037
cellular response to monosaccharide stimulus GO:0071326 47 0.036
Mouse
synaptic vesicle transport GO:0048489 57 0.036
Worm
intrinsic apoptotic signaling pathway GO:0097193 132 0.035
synapse assembly GO:0007416 56 0.035
Worm
microtubule cytoskeleton organization GO:0000226 157 0.035
establishment of synaptic vesicle localization GO:0097480 57 0.034
Worm
regulation of cellular amine metabolic process GO:0033238 20 0.034
purine ribonucleotide metabolic process GO:0009150 290 0.034
vesicle localization GO:0051648 86 0.034
Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.034
insulin secretion involved in cellular response to glucose stimulus GO:0035773 36 0.034
Mouse
cellular response to glucose stimulus GO:0071333 45 0.033
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
regulation of cellular component size GO:0032535 121 0.033
Worm
mapk cascade GO:0000165 281 0.032
peptidyl serine phosphorylation GO:0018105 74 0.032
Mouse Worm
cellular response to carbohydrate stimulus GO:0071322 50 0.031
Mouse
neuron projection guidance GO:0097485 141 0.031
Worm
apoptotic signaling pathway GO:0097190 306 0.031
cellular amine metabolic process GO:0044106 44 0.031
centrosome duplication GO:0051298 16 0.029
carbohydrate homeostasis GO:0033500 128 0.029
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.029
microtubule organizing center organization GO:0031023 28 0.029
regulation of hormone secretion GO:0046883 88 0.029
Mouse
ras protein signal transduction GO:0007265 77 0.029
regulation of cell cycle GO:0051726 281 0.028
cellular glucose homeostasis GO:0001678 52 0.028
Mouse
peptide hormone secretion GO:0030072 109 0.028
Mouse
nucleotide metabolic process GO:0009117 332 0.028
actin cytoskeleton reorganization GO:0031532 21 0.027
positive regulation of cell development GO:0010720 237 0.027
regulation of transferase activity GO:0051338 263 0.027
regulation of protein kinase activity GO:0045859 232 0.026
negative regulation of protein metabolic process GO:0051248 282 0.026
positive regulation of protein modification process GO:0031401 299 0.026
regulation of peptide transport GO:0090087 91 0.026
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
organelle fission GO:0048285 170 0.025
negative regulation of phosphorylation GO:0042326 166 0.025
small gtpase mediated signal transduction GO:0007264 97 0.024
negative regulation of molecular function GO:0044092 258 0.024
response to monosaccharide GO:0034284 67 0.024
Mouse
regulation of secretion GO:0051046 274 0.024
Mouse
regulation of extent of cell growth GO:0061387 52 0.024
Worm
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
cellular macromolecule catabolic process GO:0044265 206 0.022
nucleoside metabolic process GO:0009116 246 0.022
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.022
Mouse
membrane organization GO:0061024 245 0.022
regulation of organelle organization GO:0033043 289 0.022
organophosphate catabolic process GO:0046434 232 0.022
centrosome cycle GO:0007098 23 0.022
regulation of mapk cascade GO:0043408 248 0.021
regulation of secretion by cell GO:1903530 249 0.021
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.021
cellular homeostasis GO:0019725 240 0.021
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.021
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 20 0.020
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.020
mitotic cell cycle process GO:1903047 159 0.020
regulation of cell size GO:0008361 72 0.020
Worm
purine nucleotide metabolic process GO:0006163 302 0.020
lymphocyte mediated immunity GO:0002449 139 0.020
purine containing compound metabolic process GO:0072521 311 0.020
centrosome organization GO:0051297 26 0.019
mitotic cell cycle GO:0000278 195 0.019
single organismal cell cell adhesion GO:0016337 131 0.019
cation transport GO:0006812 399 0.019
negative regulation of protein phosphorylation GO:0001933 126 0.019
establishment or maintenance of cell polarity GO:0007163 86 0.019
ion transmembrane transport GO:0034220 361 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
germ cell development GO:0007281 185 0.019
cellular protein catabolic process GO:0044257 155 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
transmembrane transport GO:0055085 412 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
spermatogenesis GO:0007283 284 0.018
rna processing GO:0006396 105 0.017
cell recognition GO:0008037 83 0.017
regulation of multi organism process GO:0043900 111 0.017
spermatid differentiation GO:0048515 115 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
regulation of cell growth GO:0001558 91 0.017
Worm
ribonucleotide metabolic process GO:0009259 291 0.017
aromatic compound catabolic process GO:0019439 286 0.017
regulation of cell motility GO:2000145 236 0.017
inflammatory response GO:0006954 244 0.017
monosaccharide metabolic process GO:0005996 106 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
male gamete generation GO:0048232 285 0.016
vesicle organization GO:0016050 60 0.016
protein catabolic process GO:0030163 221 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
regulation of proteolysis GO:0030162 164 0.016
negative regulation of kinase activity GO:0033673 81 0.016
developmental maturation GO:0021700 193 0.016
sensory organ morphogenesis GO:0090596 242 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
regulation of postsynaptic membrane potential GO:0060078 48 0.016
cell cell junction organization GO:0045216 72 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
glycoprotein metabolic process GO:0009100 116 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
positive regulation of cell death GO:0010942 224 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
regulation of anatomical structure size GO:0090066 178 0.015
Worm
immune effector process GO:0002252 321 0.015
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.015
oxidation reduction process GO:0055114 342 0.015
locomotory behavior GO:0007626 195 0.015
cell cycle g2 m phase transition GO:0044839 20 0.015
positive regulation of nervous system development GO:0051962 221 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
intracellular mrna localization GO:0008298 4 0.015
muscle tissue development GO:0060537 308 0.015
neural precursor cell proliferation GO:0061351 121 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
developmental growth involved in morphogenesis GO:0060560 138 0.015
Worm
positive regulation of kinase activity GO:0033674 155 0.015
leukocyte mediated immunity GO:0002443 174 0.015
intracellular protein transport GO:0006886 204 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
negative regulation of transferase activity GO:0051348 85 0.015
regulation of gamma aminobutyric acid secretion GO:0014052 2 0.015
ear development GO:0043583 200 0.014
carbohydrate metabolic process GO:0005975 230 0.014
epithelial cell development GO:0002064 159 0.014
cell growth GO:0016049 130 0.014
Worm
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
cell cell adhesion GO:0098609 41 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
negative regulation of protein modification process GO:0031400 163 0.014
fertilization GO:0009566 127 0.014
mrna splicing via spliceosome GO:0000398 43 0.014
synaptic vesicle localization GO:0097479 59 0.014
Worm
regulation of apoptotic signaling pathway GO:2001233 197 0.014
mrna processing GO:0006397 63 0.014
positive regulation of transferase activity GO:0051347 167 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
negative regulation of cell proliferation GO:0008285 296 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
cellular chemical homeostasis GO:0055082 215 0.013
Mouse
peptidyl amino acid modification GO:0018193 336 0.013
Mouse Worm
membrane depolarization GO:0051899 64 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
regulation of cell activation GO:0050865 289 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
microtubule based process GO:0007017 236 0.013
regulation of intracellular transport GO:0032386 159 0.013
oocyte construction GO:0007308 2 0.013
regulation of protein localization GO:0032880 231 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
regulation of transmembrane transport GO:0034762 128 0.013
cognition GO:0050890 149 0.013
dendrite development GO:0016358 115 0.012
rac protein signal transduction GO:0016601 13 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
cation transmembrane transport GO:0098655 266 0.012
organic cyclic compound catabolic process GO:1901361 295 0.012
positive regulation of growth GO:0045927 104 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
protein ubiquitination GO:0016567 171 0.012
negative regulation of immune system process GO:0002683 209 0.012
fatty acid metabolic process GO:0006631 121 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
organelle assembly GO:0070925 177 0.012
purine containing compound catabolic process GO:0072523 213 0.012
regulation of cell migration GO:0030334 219 0.012
rho protein signal transduction GO:0007266 32 0.012
lateral inhibition GO:0046331 1 0.012
heterocycle catabolic process GO:0046700 280 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
regulation of exocytosis GO:0017157 61 0.012
cellular response to insulin stimulus GO:0032869 78 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
divalent inorganic cation transport GO:0072511 178 0.012
rna splicing GO:0008380 54 0.012
monocarboxylic acid transport GO:0015718 44 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
multicellular organismal signaling GO:0035637 91 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
forebrain development GO:0030900 302 0.012
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.011
organic acid transport GO:0015849 101 0.011
mitotic cytokinesis GO:0000281 4 0.011
regulation of protein catabolic process GO:0042176 108 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
regulation of hydrolase activity GO:0051336 246 0.011
maintenance of location GO:0051235 89 0.011
macromolecule catabolic process GO:0009057 281 0.011
oocyte axis specification GO:0007309 2 0.011
nuclear division GO:0000280 158 0.011
neuron projection extension GO:1990138 64 0.011
Worm
pole plasm assembly GO:0007315 2 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
regulation of glutamate receptor signaling pathway GO:1900449 16 0.011
endomembrane system organization GO:0010256 147 0.011
rap protein signal transduction GO:0032486 3 0.011
lymphocyte proliferation GO:0046651 164 0.011
homeostasis of number of cells GO:0048872 210 0.011
compound eye development GO:0048749 1 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
regulation of neurotransmitter levels GO:0001505 87 0.011
protein maturation GO:0051604 176 0.011
response to oxidative stress GO:0006979 123 0.011
neurotransmitter transport GO:0006836 76 0.011
carboxylic acid transport GO:0046942 100 0.011
positive regulation of gtp catabolic process GO:0033126 85 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
wnt signaling pathway GO:0016055 188 0.010
protein localization to organelle GO:0033365 185 0.010
cell substrate adhesion GO:0031589 130 0.010
cellular nitrogen compound catabolic process GO:0044270 280 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
mrna metabolic process GO:0016071 84 0.010
regulation of cellular catabolic process GO:0031329 242 0.010
positive regulation of neuron projection development GO:0010976 79 0.010
renal system development GO:0072001 225 0.010
glycoprotein biosynthetic process GO:0009101 89 0.010
leukocyte differentiation GO:0002521 342 0.010
mitochondrion organization GO:0007005 134 0.010
regulation of map kinase activity GO:0043405 120 0.010
carbohydrate derivative catabolic process GO:1901136 231 0.010
ribonucleoside triphosphate catabolic process GO:0009203 199 0.010
regulation of ion transport GO:0043269 215 0.010
positive regulation of necrotic cell death GO:0010940 1 0.010
regulation of synaptic plasticity GO:0048167 87 0.010

Brsk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.016
disease of anatomical entity DOID:7 0 0.016
central nervous system disease DOID:331 0 0.013
disease of cellular proliferation DOID:14566 0 0.011