Mus musculus

52 known processes

Notch4

Notch gene homolog 4 (Drosophila)

(Aliases: Int-3,Int3)

Notch4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytokine production GO:0001816 319 0.484
Mouse
stem cell differentiation GO:0048863 268 0.450
Mouse Fly
regulation of cytokine production GO:0001817 266 0.440
regulation of cellular amino acid metabolic process GO:0006521 5 0.407
cellular amine metabolic process GO:0044106 44 0.405
amine metabolic process GO:0009308 45 0.366
positive regulation of cell death GO:0010942 224 0.365
Mouse
muscle system process GO:0003012 141 0.351
leukocyte differentiation GO:0002521 342 0.331
Mouse
positive regulation of cytokine production GO:0001819 174 0.314
blood vessel morphogenesis GO:0048514 285 0.271
regulation of protein localization GO:0032880 231 0.264
cell adhesion GO:0007155 329 0.258
Fly
regulation of cellular amine metabolic process GO:0033238 20 0.253
positive regulation of apoptotic process GO:0043065 217 0.249
Mouse
ras protein signal transduction GO:0007265 77 0.236
regulation of cellular ketone metabolic process GO:0010565 66 0.234
aortic valve morphogenesis GO:0003180 4 0.234
negative regulation of synaptic vesicle transport GO:1902804 3 0.230
anion transport GO:0006820 177 0.228
regulation of cell activation GO:0050865 289 0.221
forebrain development GO:0030900 302 0.221
Mouse
cellular amino acid metabolic process GO:0006520 103 0.213
positive regulation of programmed cell death GO:0043068 218 0.212
Mouse
locomotory behavior GO:0007626 195 0.211
leukocyte mediated immunity GO:0002443 174 0.208
small gtpase mediated signal transduction GO:0007264 97 0.204
stem cell development GO:0048864 219 0.199
Mouse Fly
myeloid cell differentiation GO:0030099 233 0.198
Mouse
cellular ketone metabolic process GO:0042180 84 0.187
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.185
Mouse Fly
regulation of muscle system process GO:0090257 80 0.180
cell type specific apoptotic process GO:0097285 268 0.178
leukocyte activation involved in immune response GO:0002366 126 0.172
response to decreased oxygen levels GO:0036293 59 0.167
Mouse
regulation of cell motility GO:2000145 236 0.165
Mouse
single organismal cell cell adhesion GO:0016337 131 0.164
positive regulation of protein modification process GO:0031401 299 0.164
central nervous system neuron development GO:0021954 67 0.158
homeostasis of number of cells GO:0048872 210 0.157
Fly
immune effector process GO:0002252 321 0.157
nitrogen compound transport GO:0071705 271 0.155
calcium ion transport GO:0006816 159 0.154
lung development GO:0030324 164 0.150
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.146
axonogenesis GO:0007409 274 0.142
Mouse Fly
morphogenesis of embryonic epithelium GO:0016331 159 0.137
glial cell differentiation GO:0010001 131 0.131
Mouse Fly
epithelial cell development GO:0002064 159 0.129
Mouse Fly
b cell activation GO:0042113 161 0.128
positive regulation of neuron differentiation GO:0045666 141 0.127
transmembrane transport GO:0055085 412 0.127
ureteric bud development GO:0001657 94 0.126
regulation of lymphocyte proliferation GO:0050670 117 0.126
erythrocyte differentiation GO:0030218 88 0.125
developmental maturation GO:0021700 193 0.124
Mouse
regulation of cell migration GO:0030334 219 0.122
Mouse
divalent metal ion transport GO:0070838 172 0.121
cation transport GO:0006812 399 0.121
regulation of protein kinase activity GO:0045859 232 0.119
regulation of neuron projection development GO:0010975 169 0.118
regulation of b cell activation GO:0050864 81 0.117
central nervous system neuron differentiation GO:0021953 162 0.116
mesenchymal cell development GO:0014031 93 0.116
Mouse
positive regulation of nervous system development GO:0051962 221 0.114
Mouse
divalent inorganic cation transport GO:0072511 178 0.112
negative regulation of protein modification process GO:0031400 163 0.111
regulation of system process GO:0044057 200 0.111
regulation of response to wounding GO:1903034 189 0.108
regulation of neurotransmitter levels GO:0001505 87 0.107
mesenchymal cell differentiation GO:0048762 107 0.107
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.107
t cell activation GO:0042110 289 0.106
bmp signaling pathway GO:0030509 93 0.106
Mouse
protein modification by small protein conjugation GO:0032446 187 0.105
muscle cell differentiation GO:0042692 261 0.105
Mouse Fly
regulation of cellular catabolic process GO:0031329 242 0.104
cytokine secretion GO:0050663 72 0.104
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.103
Mouse
metal ion homeostasis GO:0055065 189 0.103
regulation of b cell proliferation GO:0030888 39 0.102
cation homeostasis GO:0055080 212 0.102
respiratory system development GO:0060541 190 0.101
Mouse Fly
positive regulation of cell activation GO:0050867 158 0.100
cardiac right ventricle formation GO:0003219 3 0.100
Mouse
cardiocyte differentiation GO:0035051 87 0.100
Mouse Fly
stem cell maintenance GO:0019827 130 0.099
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.099
apoptotic signaling pathway GO:0097190 306 0.099
myeloid leukocyte differentiation GO:0002573 119 0.098
Mouse
digestive tract development GO:0048565 190 0.098
Mouse Worm Fly
male gamete generation GO:0048232 285 0.098
regulation of neuron differentiation GO:0045664 281 0.097
Mouse Fly
immune response activating signal transduction GO:0002757 116 0.096
t cell differentiation GO:0030217 174 0.096
protein ubiquitination GO:0016567 171 0.095
anatomical structure homeostasis GO:0060249 145 0.095
regulation of transmembrane transport GO:0034762 128 0.094
b cell proliferation GO:0042100 53 0.094
carbohydrate homeostasis GO:0033500 128 0.094
response to organic cyclic compound GO:0014070 198 0.093
positive regulation of bmp signaling pathway GO:0030513 23 0.092
Mouse
cell fate specification GO:0001708 72 0.092
Mouse Worm Fly
heart morphogenesis GO:0003007 178 0.092
Mouse
regulation of lymphocyte activation GO:0051249 240 0.091
cellular response to lipid GO:0071396 145 0.091
somitogenesis GO:0001756 69 0.091
Mouse
regulation of secretion GO:0051046 274 0.091
Mouse
glucose homeostasis GO:0042593 128 0.091
adaptive immune response GO:0002250 155 0.090
ribose phosphate metabolic process GO:0019693 291 0.090
purine containing compound metabolic process GO:0072521 311 0.089
negative regulation of multi organism process GO:0043901 68 0.089
exocytosis GO:0006887 121 0.089
Mouse
regulation of body fluid levels GO:0050878 162 0.089
leukocyte proliferation GO:0070661 172 0.088
germ cell development GO:0007281 185 0.088
Fly
myeloid leukocyte activation GO:0002274 83 0.088
Mouse
regulation of cellular response to stress GO:0080135 159 0.086
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.086
cellular homeostasis GO:0019725 240 0.085
regulation of ras gtpase activity GO:0032318 88 0.085
organic anion transport GO:0015711 137 0.084
extracellular matrix organization GO:0030198 147 0.083
Mouse
muscle contraction GO:0006936 101 0.083
organelle localization GO:0051640 179 0.083
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.082
renal system development GO:0072001 225 0.082
Mouse Fly
epithelial tube morphogenesis GO:0060562 303 0.082
protein modification by small protein conjugation or removal GO:0070647 207 0.082
cellular response to dna damage stimulus GO:0006974 207 0.082
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.081
ameboidal type cell migration GO:0001667 128 0.081
Fly
positive regulation of nucleotide metabolic process GO:0045981 114 0.081
embryonic epithelial tube formation GO:0001838 130 0.080
notch signaling pathway GO:0007219 71 0.080
Mouse Fly
leukocyte migration GO:0050900 124 0.079
organelle assembly GO:0070925 177 0.079
neuron migration GO:0001764 122 0.079
heart valve morphogenesis GO:0003179 21 0.078
Mouse
astrocyte fate commitment GO:0060018 4 0.078
digestive system development GO:0055123 200 0.078
Mouse Worm Fly
cell activation involved in immune response GO:0002263 126 0.078
response to oxidative stress GO:0006979 123 0.077
regulation of leukocyte proliferation GO:0070663 121 0.077
mesenchyme development GO:0060485 152 0.076
Mouse
positive regulation of secretion GO:0051047 130 0.076
angiogenesis GO:0001525 201 0.075
regulation of nucleotide metabolic process GO:0006140 169 0.075
nucleoside phosphate metabolic process GO:0006753 338 0.074
sensory perception GO:0007600 245 0.074
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.074
regulation of heart growth GO:0060420 31 0.073
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.073
spinal cord development GO:0021510 81 0.073
neuromuscular process GO:0050905 99 0.073
lymphocyte differentiation GO:0030098 242 0.072
cellular response to molecule of bacterial origin GO:0071219 83 0.072
rhythmic process GO:0048511 174 0.072
skeletal muscle organ development GO:0060538 163 0.072
Mouse Fly
regulation of secretion by cell GO:1903530 249 0.072
Mouse
epithelial tube formation GO:0072175 130 0.072
single organism cell adhesion GO:0098602 156 0.071
cell differentiation in spinal cord GO:0021515 53 0.071
carboxylic acid transport GO:0046942 100 0.071
negative regulation of cellular amine metabolic process GO:0033239 1 0.071
cardiac septum development GO:0003279 59 0.070
Mouse
cellular response to inorganic substance GO:0071241 37 0.070
muscle cell development GO:0055001 133 0.070
Mouse
peptidyl tyrosine modification GO:0018212 145 0.069
alpha beta t cell differentiation GO:0046632 69 0.069
aromatic compound catabolic process GO:0019439 286 0.069
negative regulation of molecular function GO:0044092 258 0.068
Mouse
negative regulation of cell activation GO:0050866 111 0.068
cardiac chamber morphogenesis GO:0003206 93 0.068
Mouse
cardiac ventricle development GO:0003231 83 0.068
Mouse
response to calcium ion GO:0051592 20 0.068
telencephalon development GO:0021537 186 0.067
multicellular organismal homeostasis GO:0048871 164 0.066
regulation of membrane potential GO:0042391 192 0.066
cation transmembrane transport GO:0098655 266 0.066
cellular response to calcium ion GO:0071277 14 0.066
morphogenesis of a branching epithelium GO:0061138 193 0.066
negative regulation of protein metabolic process GO:0051248 282 0.066
regulation of t cell activation GO:0050863 170 0.066
lymphocyte proliferation GO:0046651 164 0.065
activation of immune response GO:0002253 138 0.065
immune response regulating signaling pathway GO:0002764 125 0.065
negative regulation of growth GO:0045926 99 0.065
neurotransmitter transport GO:0006836 76 0.065
alpha beta t cell activation GO:0046631 91 0.065
lateral inhibition GO:0046331 1 0.065
Fly
blood circulation GO:0008015 195 0.064
endocytosis GO:0006897 168 0.064
Worm
regulation of cell projection organization GO:0031344 206 0.064
Fly
intracellular distribution of mitochondria GO:0048312 1 0.064
embryonic organ morphogenesis GO:0048562 276 0.064
Mouse
mapk cascade GO:0000165 281 0.063
myotube differentiation GO:0014902 105 0.063
Mouse
transdifferentiation GO:0060290 1 0.063
regulation of ras protein signal transduction GO:0046578 114 0.063
heart trabecula morphogenesis GO:0061384 26 0.063
Mouse
regulation of calcium mediated signaling GO:0050848 19 0.063
positive regulation of cell motility GO:2000147 116 0.062
Mouse
cellular chemical homeostasis GO:0055082 215 0.062
organic hydroxy compound metabolic process GO:1901615 203 0.061
positive regulation of protein phosphorylation GO:0001934 242 0.061
neural crest cell migration GO:0001755 32 0.061
negative regulation of immune system process GO:0002683 209 0.061
Mouse
calcium ion homeostasis GO:0055074 127 0.061
regulation of organ growth GO:0046620 61 0.061
Mouse
defense response to other organism GO:0098542 197 0.060
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.060
synaptic transmission GO:0007268 329 0.060
positive regulation of leukocyte proliferation GO:0070665 73 0.059
circadian rhythm GO:0007623 114 0.059
cardiac muscle cell differentiation GO:0055007 69 0.059
epithelial cell proliferation GO:0050673 174 0.058
Mouse Fly
nucleobase containing small molecule metabolic process GO:0055086 352 0.058
negative regulation of secretion GO:0051048 61 0.058
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.057
Mouse Fly
protein secretion GO:0009306 111 0.057
Mouse
forebrain generation of neurons GO:0021872 63 0.057
ribonucleotide metabolic process GO:0009259 291 0.057
positive regulation of cellular amine metabolic process GO:0033240 5 0.057
peptidyl amino acid modification GO:0018193 336 0.056
peptidyl tyrosine phosphorylation GO:0018108 143 0.056
regulation of myeloid cell differentiation GO:0045637 96 0.056
Mouse
muscle adaptation GO:0043500 39 0.056
regulation of auditory receptor cell differentiation GO:0045607 4 0.056
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.055
Mouse
purine nucleoside metabolic process GO:0042278 241 0.054
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.054
generation of precursor metabolites and energy GO:0006091 103 0.054
regulation of binding GO:0051098 111 0.053
forebrain neuron development GO:0021884 30 0.053
myeloid cell homeostasis GO:0002262 114 0.053
oligodendrocyte differentiation GO:0048709 53 0.053
Mouse
autonomic nervous system development GO:0048483 43 0.053
skeletal system morphogenesis GO:0048705 203 0.053
neural tube patterning GO:0021532 43 0.053
response to monosaccharide GO:0034284 67 0.053
positive regulation of lymphocyte activation GO:0051251 140 0.053
pallium development GO:0021543 120 0.053
ribonucleoside metabolic process GO:0009119 245 0.052
mesonephric epithelium development GO:0072163 94 0.052
heart process GO:0003015 94 0.052
divalent inorganic cation homeostasis GO:0072507 138 0.052
regulation of leukocyte mediated immunity GO:0002703 104 0.052
purine nucleotide catabolic process GO:0006195 211 0.052
regulation of vesicle mediated transport GO:0060627 139 0.052
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.052
regulation of homeostatic process GO:0032844 182 0.051
negative regulation of cytokine production GO:0001818 84 0.051
purine nucleoside triphosphate metabolic process GO:0009144 226 0.051
mesonephric tubule development GO:0072164 94 0.051
negative regulation of cell proliferation GO:0008285 296 0.050
Mouse
morphogenesis of a branching structure GO:0001763 203 0.050
response to organonitrogen compound GO:0010243 246 0.050
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.050
positive regulation of hydrolase activity GO:0051345 148 0.050
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.050
Mouse
heart growth GO:0060419 45 0.049
Mouse
development of primary sexual characteristics GO:0045137 143 0.049
Worm
regulation of defense response GO:0031347 233 0.049
cell recognition GO:0008037 83 0.049
circulatory system process GO:0003013 197 0.049
cellular divalent inorganic cation homeostasis GO:0072503 127 0.049
positive regulation of b cell activation GO:0050871 49 0.048
jak stat cascade GO:0007259 42 0.048
Mouse
organelle fission GO:0048285 170 0.048
Worm
inositol phosphate mediated signaling GO:0048016 13 0.048
regulation of neural retina development GO:0061074 3 0.047
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.047
purine nucleotide metabolic process GO:0006163 302 0.047
neural tube development GO:0021915 160 0.047
Mouse
regionalization GO:0003002 337 0.047
Mouse Fly
negative regulation of neuron differentiation GO:0045665 101 0.047
Mouse Fly
sensory organ morphogenesis GO:0090596 242 0.047
Mouse Fly
response to lipopolysaccharide GO:0032496 128 0.046
cellular calcium ion homeostasis GO:0006874 119 0.046
positive regulation of cell development GO:0010720 237 0.046
Mouse
regulation of nucleoside metabolic process GO:0009118 130 0.046
epithelial cell morphogenesis GO:0003382 41 0.046
ventral spinal cord development GO:0021517 48 0.046
negative regulation of synapse maturation GO:2000297 2 0.046
positive regulation of defense response GO:0031349 124 0.046
mesonephros development GO:0001823 97 0.045
embryonic heart tube morphogenesis GO:0003143 51 0.045
Mouse
intrinsic apoptotic signaling pathway GO:0097193 132 0.045
nucleotide metabolic process GO:0009117 332 0.045
cellular metal ion homeostasis GO:0006875 151 0.045
tube formation GO:0035148 140 0.045
ribonucleoside triphosphate metabolic process GO:0009199 220 0.045
negative regulation of nervous system development GO:0051961 156 0.044
Mouse Fly
interferon gamma production GO:0032609 67 0.044
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.044
extracellular structure organization GO:0043062 148 0.044
Mouse
cardiac ventricle morphogenesis GO:0003208 50 0.044
Mouse
regulation of muscle contraction GO:0006937 49 0.044
leukocyte apoptotic process GO:0071887 71 0.044
purine ribonucleotide metabolic process GO:0009150 290 0.044
positive regulation of b cell proliferation GO:0030890 24 0.044
positive regulation of homeostatic process GO:0032846 64 0.043
cellular response to monosaccharide stimulus GO:0071326 47 0.043
organic cyclic compound catabolic process GO:1901361 295 0.043
insulin secretion GO:0030073 89 0.043
axon guidance GO:0007411 141 0.043
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.042
gliogenesis GO:0042063 141 0.042
Mouse Fly
ear development GO:0043583 200 0.042
Mouse
neural crest cell differentiation GO:0014033 54 0.042
ion transmembrane transport GO:0034220 361 0.042
determination of heart left right asymmetry GO:0061371 48 0.042
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.042
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.042
regulation of tumor necrosis factor production GO:0032680 49 0.042
embryonic heart tube development GO:0035050 65 0.042
Mouse
neurotransmitter secretion GO:0007269 62 0.042
response to inorganic substance GO:0010035 96 0.041
skeletal system development GO:0001501 356 0.041
negative regulation of protein phosphorylation GO:0001933 126 0.041
mammary gland epithelium development GO:0061180 65 0.041
nephron epithelium morphogenesis GO:0072088 68 0.041
positive regulation of apoptotic signaling pathway GO:2001235 95 0.041
negative regulation of cell development GO:0010721 169 0.041
Mouse Fly
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.041
neural tube closure GO:0001843 90 0.040
diencephalon development GO:0021536 63 0.040
organonitrogen compound biosynthetic process GO:1901566 192 0.040
positive regulation of cellular catabolic process GO:0031331 148 0.040
positive regulation of organelle organization GO:0010638 128 0.040
regulation of chromosome organization GO:0033044 83 0.040
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.040
positive regulation of secretion by cell GO:1903532 114 0.040
negative regulation of synapse assembly GO:0051964 3 0.040
mesonephric tubule morphogenesis GO:0072171 63 0.040
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.040
regulation of leukocyte apoptotic process GO:2000106 56 0.040
positive regulation of nucleotide catabolic process GO:0030813 88 0.040
regulation of retina development in camera type eye GO:1902866 3 0.040
synaptic vesicle localization GO:0097479 59 0.039
second messenger mediated signaling GO:0019932 73 0.039
epithelial cell migration GO:0010631 63 0.039
Fly
regulation of protein serine threonine kinase activity GO:0071900 157 0.039
kidney development GO:0001822 213 0.039
Mouse
fat cell differentiation GO:0045444 160 0.039
purine nucleoside catabolic process GO:0006152 205 0.039
negative regulation of phosphorylation GO:0042326 166 0.038
negative regulation of lymphocyte activation GO:0051250 91 0.038
regulation of circadian rhythm GO:0042752 58 0.038
regulation of kinase activity GO:0043549 249 0.038
response to growth factor GO:0070848 198 0.038
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.038
innate immune response GO:0045087 157 0.038
somatic stem cell maintenance GO:0035019 47 0.038
regulation of notch signaling pathway GO:0008593 35 0.038
Fly
ossification GO:0001503 216 0.038
Mouse
glomerulus development GO:0032835 40 0.038
Mouse
ventricular septum development GO:0003281 42 0.038
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.037
Mouse
regulation of cell cycle GO:0051726 281 0.037
Worm Fly
cellular response to glucose stimulus GO:0071333 45 0.037
vesicle localization GO:0051648 86 0.037
glomerular mesangial cell development GO:0072144 3 0.037
Mouse
gtp catabolic process GO:0006184 143 0.037
calcium mediated signaling GO:0019722 46 0.037
organonitrogen compound catabolic process GO:1901565 264 0.037
pulmonary valve development GO:0003177 5 0.036
positive regulation of mapk cascade GO:0043410 170 0.036
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.036
coronary vasculature development GO:0060976 12 0.036
Mouse
neural tube formation GO:0001841 108 0.036
i kappab kinase nf kappab signaling GO:0007249 85 0.036
Fly
primary neural tube formation GO:0014020 95 0.036
cognition GO:0050890 149 0.036
Fly
nephron tubule morphogenesis GO:0072078 68 0.036
regulation of organelle organization GO:0033043 289 0.036
Worm
neuron recognition GO:0008038 25 0.036
regulation of exocytosis GO:0017157 61 0.036
Mouse
leukocyte homeostasis GO:0001776 79 0.035
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.035
regulation of myeloid leukocyte differentiation GO:0002761 58 0.035
Mouse
regulation of establishment of protein localization GO:0070201 181 0.035
response to molecule of bacterial origin GO:0002237 143 0.035
response to radiation GO:0009314 165 0.035
regulation of purine nucleotide metabolic process GO:1900542 169 0.035
cellular response to acid chemical GO:0071229 68 0.035
hemostasis GO:0007599 78 0.035
urogenital system development GO:0001655 261 0.035
Mouse Fly
mitochondrion organization GO:0007005 134 0.035
pulmonary valve morphogenesis GO:0003184 5 0.035
kidney epithelium development GO:0072073 121 0.035
Mouse
positive regulation of mitotic cell cycle GO:0045931 41 0.034
Fly
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.034
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.034
regulation of hydrolase activity GO:0051336 246 0.034
auditory receptor cell fate determination GO:0042668 3 0.034
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.034
tumor necrosis factor production GO:0032640 50 0.034
cellular response to biotic stimulus GO:0071216 92 0.034
actin cytoskeleton organization GO:0030036 220 0.033
Fly
ribonucleotide catabolic process GO:0009261 208 0.033
branching morphogenesis of an epithelial tube GO:0048754 159 0.033
cellular response to carbohydrate stimulus GO:0071322 50 0.033
modification dependent protein catabolic process GO:0019941 133 0.033
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.033
positive regulation of lymphocyte proliferation GO:0050671 70 0.033
multicellular organism growth GO:0035264 161 0.033
b cell differentiation GO:0030183 78 0.033
carbohydrate metabolic process GO:0005975 230 0.033
carbohydrate derivative catabolic process GO:1901136 231 0.033
positive regulation of interleukin 8 production GO:0032757 2 0.033
lymphocyte activation involved in immune response GO:0002285 93 0.032
multi multicellular organism process GO:0044706 109 0.032
Worm
response to oxygen levels GO:0070482 62 0.032
Mouse
organic acid transport GO:0015849 101 0.032
endodermal cell fate specification GO:0001714 4 0.032
negative regulation of ossification GO:0030279 49 0.032
Mouse
thymus development GO:0048538 41 0.032
spermatogenesis GO:0007283 284 0.032
epithelial to mesenchymal transition GO:0001837 47 0.032
Mouse
peptide secretion GO:0002790 114 0.032
blastocyst development GO:0001824 80 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.032
negative regulation of t cell activation GO:0050868 65 0.032
regulation of mesenchymal cell proliferation GO:0010464 37 0.032
regulation of anatomical structure size GO:0090066 178 0.032
ureteric bud morphogenesis GO:0060675 62 0.032
regulation of wnt signaling pathway GO:0030111 123 0.031
Mouse
associative learning GO:0008306 61 0.031
inner ear morphogenesis GO:0042472 101 0.031
antigen receptor mediated signaling pathway GO:0050851 64 0.031
smoothened signaling pathway GO:0007224 105 0.031
response to metal ion GO:0010038 47 0.031
purine nucleoside triphosphate catabolic process GO:0009146 203 0.031
positive regulation of keratinocyte proliferation GO:0010838 4 0.031
regulation of ossification GO:0030278 112 0.031
Mouse
compound eye development GO:0048749 1 0.031
Fly
regulation of protein catabolic process GO:0042176 108 0.031
interleukin 8 secretion GO:0072606 3 0.031
cellular response to abiotic stimulus GO:0071214 56 0.031
heterocycle catabolic process GO:0046700 280 0.031
sclerotome development GO:0061056 4 0.031
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.031
establishment of synaptic vesicle localization GO:0097480 57 0.030
negative regulation of neuron projection development GO:0010977 50 0.030
regulation of innate immune response GO:0045088 91 0.030
retina morphogenesis in camera type eye GO:0060042 45 0.030
negative regulation of synaptic vesicle exocytosis GO:2000301 3 0.030
osteoclast differentiation GO:0030316 62 0.030
Mouse
cell fate commitment GO:0045165 210 0.030
Mouse Worm Fly
response to temperature stimulus GO:0009266 55 0.030
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.030
lymphocyte mediated immunity GO:0002449 139 0.030
regulation of ion transport GO:0043269 215 0.030
cell fate determination GO:0001709 32 0.030
Fly
camera type eye development GO:0043010 266 0.030
Mouse
syncytium formation by plasma membrane fusion GO:0000768 42 0.029
positive regulation of gtp catabolic process GO:0033126 85 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.029
response to steroid hormone GO:0048545 56 0.029
purine ribonucleotide catabolic process GO:0009154 208 0.029
camp metabolic process GO:0046058 40 0.029
neuron projection guidance GO:0097485 141 0.029
Fly
regulation of ion transmembrane transport GO:0034765 119 0.029
regulation of cysteine type endopeptidase activity GO:2000116 65 0.029
establishment of vesicle localization GO:0051650 81 0.029
nephron morphogenesis GO:0072028 69 0.029
mesoderm morphogenesis GO:0048332 64 0.029
ventricular septum morphogenesis GO:0060412 27 0.029
tissue migration GO:0090130 68 0.028
Fly
striated muscle adaptation GO:0014888 26 0.028
nucleoside triphosphate metabolic process GO:0009141 230 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.028
cell chemotaxis GO:0060326 81 0.028
ear morphogenesis GO:0042471 118 0.028
interleukin 8 production GO:0032637 4 0.028
protein localization to membrane GO:0072657 108 0.028
ubiquitin dependent protein catabolic process GO:0006511 129 0.028
positive regulation of interleukin 8 secretion GO:2000484 1 0.028
mitotic cell cycle process GO:1903047 159 0.028
Fly
regulation of fat cell differentiation GO:0045598 81 0.028
positive regulation of immune effector process GO:0002699 107 0.028
cellular response to hexose stimulus GO:0071331 47 0.028
regulation of bmp signaling pathway GO:0030510 60 0.028
Mouse
olfactory lobe development GO:0021988 32 0.028
ribonucleoside triphosphate catabolic process GO:0009203 199 0.028
regulation of organ morphogenesis GO:2000027 144 0.028
Mouse Fly
mitochondrion distribution GO:0048311 4 0.027
positive regulation of insulin secretion GO:0032024 26 0.027
cellular respiration GO:0045333 38 0.027
cellular response to external stimulus GO:0071496 88 0.027
actin filament organization GO:0007015 113 0.027
Fly
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.027
regulation of peptide transport GO:0090087 91 0.027

Notch4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.050
nervous system disease DOID:863 0 0.050