Mus musculus

77 known processes

Zfp281

zinc finger protein 281

(Aliases: MGC7737,MGC70044)

Zfp281 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.274
cellular ketone metabolic process GO:0042180 84 0.127
regulation of cellular amino acid metabolic process GO:0006521 5 0.119
hematopoietic progenitor cell differentiation GO:0002244 143 0.117
protein modification by small protein conjugation GO:0032446 187 0.114
negative regulation of protein metabolic process GO:0051248 282 0.108
regulation of cellular ketone metabolic process GO:0010565 66 0.107
amine metabolic process GO:0009308 45 0.102
t cell activation GO:0042110 289 0.099
purine containing compound catabolic process GO:0072523 213 0.098
modification dependent macromolecule catabolic process GO:0043632 133 0.098
homeostasis of number of cells GO:0048872 210 0.090
purine containing compound metabolic process GO:0072521 311 0.086
protein ubiquitination GO:0016567 171 0.085
regulation of mapk cascade GO:0043408 248 0.083
negative regulation of cellular amine metabolic process GO:0033239 1 0.082
protein modification by small protein conjugation or removal GO:0070647 207 0.081
negative regulation of molecular function GO:0044092 258 0.077
negative regulation of cell proliferation GO:0008285 296 0.073
mapk cascade GO:0000165 281 0.070
peptidyl amino acid modification GO:0018193 336 0.069
regulation of cellular response to stress GO:0080135 159 0.069
stem cell development GO:0048864 219 0.068
negative regulation of cellular protein metabolic process GO:0032269 247 0.066
covalent chromatin modification GO:0016569 163 0.066
dna metabolic process GO:0006259 303 0.063
regulation of hydrolase activity GO:0051336 246 0.061
regulation of cellular amine metabolic process GO:0033238 20 0.058
leukocyte differentiation GO:0002521 342 0.056
aromatic compound catabolic process GO:0019439 286 0.056
nucleoside phosphate catabolic process GO:1901292 222 0.054
cellular amino acid metabolic process GO:0006520 103 0.053
regulation of defense response GO:0031347 233 0.053
cellular amine metabolic process GO:0044106 44 0.052
organonitrogen compound catabolic process GO:1901565 264 0.052
regulation of protein complex assembly GO:0043254 83 0.051
regulation of organelle organization GO:0033043 289 0.050
innate immune response GO:0045087 157 0.049
gland development GO:0048732 330 0.048
cellular nitrogen compound catabolic process GO:0044270 280 0.046
negative regulation of phosphate metabolic process GO:0045936 184 0.046
positive regulation of mapk cascade GO:0043410 170 0.045
nucleoside phosphate metabolic process GO:0006753 338 0.045
regulation of cytoskeleton organization GO:0051493 122 0.045
chromatin modification GO:0016568 187 0.045
glycosyl compound catabolic process GO:1901658 206 0.045
nucleoside triphosphate catabolic process GO:0009143 205 0.044
purine ribonucleoside catabolic process GO:0046130 205 0.043
positive regulation of programmed cell death GO:0043068 218 0.042
cell type specific apoptotic process GO:0097285 268 0.041
regulation of innate immune response GO:0045088 91 0.040
modification dependent protein catabolic process GO:0019941 133 0.040
ribonucleoside triphosphate metabolic process GO:0009199 220 0.040
positive regulation of cell death GO:0010942 224 0.039
skeletal system morphogenesis GO:0048705 203 0.039
regulation of cell migration GO:0030334 219 0.038
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.038
negative regulation of hydrolase activity GO:0051346 71 0.038
t cell differentiation GO:0030217 174 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.038
glycosyl compound metabolic process GO:1901657 246 0.037
organelle fission GO:0048285 170 0.036
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.036
ribose phosphate metabolic process GO:0019693 291 0.035
posttranscriptional regulation of gene expression GO:0010608 155 0.034
intracellular receptor signaling pathway GO:0030522 74 0.034
regulation of neuron differentiation GO:0045664 281 0.033
purine nucleotide metabolic process GO:0006163 302 0.033
negative regulation of phosphorylation GO:0042326 166 0.033
negative regulation of protein modification process GO:0031400 163 0.033
positive regulation of nervous system development GO:0051962 221 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.031
activation of immune response GO:0002253 138 0.031
regulation of lymphocyte activation GO:0051249 240 0.030
chromatin organization GO:0006325 206 0.030
response to organic cyclic compound GO:0014070 198 0.030
purine ribonucleotide catabolic process GO:0009154 208 0.030
nuclear division GO:0000280 158 0.030
stem cell differentiation GO:0048863 268 0.029
negative regulation of cellular component organization GO:0051129 194 0.029
organic cyclic compound catabolic process GO:1901361 295 0.029
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.028
neural tube development GO:0021915 160 0.028
nucleoside metabolic process GO:0009116 246 0.028
muscle tissue development GO:0060537 308 0.028
regulation of proteolysis GO:0030162 164 0.027
lymphocyte differentiation GO:0030098 242 0.027
rna processing GO:0006396 105 0.027
response to organonitrogen compound GO:0010243 246 0.027
negative regulation of phosphorus metabolic process GO:0010563 184 0.027
regulation of cellular component biogenesis GO:0044087 181 0.027
cellular response to lipid GO:0071396 145 0.027
regulation of cell activation GO:0050865 289 0.026
negative regulation of lymphocyte activation GO:0051250 91 0.026
cellular response to dna damage stimulus GO:0006974 207 0.026
cellular response to starvation GO:0009267 57 0.026
ribonucleoside metabolic process GO:0009119 245 0.026
lymphocyte proliferation GO:0046651 164 0.025
positive regulation of leukocyte differentiation GO:1902107 86 0.025
organophosphate catabolic process GO:0046434 232 0.025
positive regulation of cell development GO:0010720 237 0.025
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.025
photoreceptor cell differentiation GO:0046530 52 0.025
regulation of ion transport GO:0043269 215 0.025
ossification GO:0001503 216 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
nucleoside triphosphate metabolic process GO:0009141 230 0.024
b cell activation GO:0042113 161 0.024
ribonucleoside monophosphate metabolic process GO:0009161 80 0.024
positive regulation of macroautophagy GO:0016239 3 0.024
purine ribonucleoside metabolic process GO:0046128 241 0.024
rhythmic process GO:0048511 174 0.023
placenta development GO:0001890 140 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
cell maturation GO:0048469 127 0.023
oocyte construction GO:0007308 2 0.023
heterocycle catabolic process GO:0046700 280 0.023
cellular lipid metabolic process GO:0044255 323 0.022
myeloid cell differentiation GO:0030099 233 0.022
ubiquitin dependent protein catabolic process GO:0006511 129 0.022
cellular response to organonitrogen compound GO:0071417 145 0.022
blood vessel morphogenesis GO:0048514 285 0.022
lipid biosynthetic process GO:0008610 179 0.022
positive regulation of innate immune response GO:0045089 80 0.022
protein catabolic process GO:0030163 221 0.022
regulation of leukocyte differentiation GO:1902105 159 0.022
regulation of protein stability GO:0031647 52 0.021
regulation of protein kinase activity GO:0045859 232 0.021
macromolecule catabolic process GO:0009057 281 0.021
spermatogenesis GO:0007283 284 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
regulation of secretion GO:0051046 274 0.021
regulation of feeding behavior GO:0060259 3 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.020
positive regulation of cellular component biogenesis GO:0044089 94 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
regulation of t cell activation GO:0050863 170 0.020
negative regulation of t cell activation GO:0050868 65 0.020
regulation of cell motility GO:2000145 236 0.020
fat cell differentiation GO:0045444 160 0.020
negative regulation of protein phosphorylation GO:0001933 126 0.020
leukocyte proliferation GO:0070661 172 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.019
endocytosis GO:0006897 168 0.019
developmental maturation GO:0021700 193 0.019
skeletal system development GO:0001501 356 0.019
regulation of purine nucleotide metabolic process GO:1900542 169 0.019
regulation of epithelial cell proliferation GO:0050678 141 0.019
nucleotide catabolic process GO:0009166 217 0.019
male gamete generation GO:0048232 285 0.019
regulation of nucleoside metabolic process GO:0009118 130 0.019
rho protein signal transduction GO:0007266 32 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
epithelial cell proliferation GO:0050673 174 0.019
purine nucleoside monophosphate metabolic process GO:0009126 81 0.019
purine nucleoside catabolic process GO:0006152 205 0.019
striated muscle tissue development GO:0014706 293 0.018
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
positive regulation of sequestering of triglyceride GO:0010890 4 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
purine nucleoside metabolic process GO:0042278 241 0.017
regulation of erk1 and erk2 cascade GO:0070372 71 0.017
cellular protein catabolic process GO:0044257 155 0.017
immune response activating signal transduction GO:0002757 116 0.017
response to lipopolysaccharide GO:0032496 128 0.017
rna splicing via transesterification reactions GO:0000375 43 0.017
b cell homeostasis GO:0001782 34 0.017
nucleotide metabolic process GO:0009117 332 0.017
atp catabolic process GO:0006200 55 0.017
erk1 and erk2 cascade GO:0070371 77 0.017
i kappab kinase nf kappab signaling GO:0007249 85 0.017
regulation of bmp signaling pathway GO:0030510 60 0.017
myeloid leukocyte differentiation GO:0002573 119 0.017
atp metabolic process GO:0046034 75 0.017
lymphocyte homeostasis GO:0002260 64 0.017
leukocyte homeostasis GO:0001776 79 0.017
developmental growth involved in morphogenesis GO:0060560 138 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.016
neuron apoptotic process GO:0051402 142 0.016
chemotaxis GO:0006935 247 0.016
gliogenesis GO:0042063 141 0.016
regulation of cell cycle process GO:0010564 160 0.016
respiratory system development GO:0060541 190 0.016
osteoclast differentiation GO:0030316 62 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
negative regulation of neuron death GO:1901215 98 0.016
response to acid chemical GO:0001101 111 0.016
defense response to bacterium GO:0042742 119 0.015
fibroblast proliferation GO:0048144 35 0.015
regulation of transcription by chromatin organization GO:0034401 0 0.015
myeloid cell homeostasis GO:0002262 114 0.015
negative regulation of proteolysis GO:0045861 74 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
detection of stimulus GO:0051606 84 0.015
cation transport GO:0006812 399 0.015
regulation of protein maturation GO:1903317 96 0.015
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.015
neuron projection guidance GO:0097485 141 0.015
negative regulation of mapk cascade GO:0043409 65 0.014
cellular response to molecule of bacterial origin GO:0071219 83 0.014
cellular response to nutrient levels GO:0031669 64 0.014
muscle cell differentiation GO:0042692 261 0.014
tube formation GO:0035148 140 0.014
neuron death GO:0070997 154 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
mesenchyme development GO:0060485 152 0.014
regulation of cellular component size GO:0032535 121 0.014
negative regulation of dna replication GO:0008156 4 0.014
multi organism behavior GO:0051705 62 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
organ growth GO:0035265 117 0.014
cell adhesion GO:0007155 329 0.014
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
regulation of secretion by cell GO:1903530 249 0.014
cellular response to growth factor stimulus GO:0071363 197 0.013
central nervous system neuron differentiation GO:0021953 162 0.013
defense response to other organism GO:0098542 197 0.013
female gonad development GO:0008585 71 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
regulation of response to dna damage stimulus GO:2001020 34 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
nucleoside catabolic process GO:0009164 206 0.013
neuronal action potential GO:0019228 54 0.013
response to radiation GO:0009314 165 0.013
negative regulation of transferase activity GO:0051348 85 0.013
embryonic epithelial tube formation GO:0001838 130 0.013
negative regulation of protein maturation GO:1903318 79 0.013
nucleoside monophosphate catabolic process GO:0009125 59 0.013
cognition GO:0050890 149 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.013
microtubule based process GO:0007017 236 0.013
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.013
connective tissue development GO:0061448 179 0.013
cell fate commitment GO:0045165 210 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
regulation of protein processing GO:0070613 96 0.013
gene silencing GO:0016458 38 0.013
bmp signaling pathway GO:0030509 93 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
positive regulation of neuron differentiation GO:0045666 141 0.012
dephosphorylation GO:0016311 129 0.012
multi multicellular organism process GO:0044706 109 0.012
regulation of cytokine production GO:0001817 266 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
peptidyl serine modification GO:0018209 83 0.012
angiogenesis GO:0001525 201 0.012
cellular response to extracellular stimulus GO:0031668 81 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
response to light stimulus GO:0009416 135 0.012
wound healing GO:0042060 157 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
immune effector process GO:0002252 321 0.012
regulation of body fluid levels GO:0050878 162 0.012
positive regulation of defense response GO:0031349 124 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
immune response regulating signaling pathway GO:0002764 125 0.012
tissue homeostasis GO:0001894 115 0.012
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
mitotic cell cycle GO:0000278 195 0.011
regulation of endopeptidase activity GO:0052548 89 0.011
response to starvation GO:0042594 65 0.011
camera type eye development GO:0043010 266 0.011
axon guidance GO:0007411 141 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
protein maturation GO:0051604 176 0.011
cell substrate adhesion GO:0031589 130 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
gastrulation GO:0007369 116 0.011
meiotic nuclear division GO:0007126 115 0.011
female sex differentiation GO:0046660 84 0.011
negative regulation of protein processing GO:0010955 79 0.011
response to extracellular stimulus GO:0009991 127 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
signal transduction by p53 class mediator GO:0072331 51 0.011
positive regulation of cytokine production GO:0001819 174 0.011
protein localization to organelle GO:0033365 185 0.011
cytokine production GO:0001816 319 0.011
inflammatory response GO:0006954 244 0.011
positive regulation of response to dna damage stimulus GO:2001022 14 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.011
circadian rhythm GO:0007623 114 0.011
positive regulation of protein ubiquitination GO:0031398 27 0.011
regulation of protein ubiquitination GO:0031396 52 0.011
ribonucleoside monophosphate catabolic process GO:0009158 57 0.011
learning or memory GO:0007611 148 0.011
regulation of protein localization GO:0032880 231 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
b cell differentiation GO:0030183 78 0.011
regulation of androgen receptor signaling pathway GO:0060765 3 0.010
negative regulation of protein catabolic process GO:0042177 36 0.010
histone modification GO:0016570 159 0.010
cation transmembrane transport GO:0098655 266 0.010
positive regulation of apoptotic process GO:0043065 217 0.010
vesicle organization GO:0016050 60 0.010
stem cell maintenance GO:0019827 130 0.010
appendage morphogenesis GO:0035107 149 0.010
lung development GO:0030324 164 0.010
heart morphogenesis GO:0003007 178 0.010
cellular response to organic cyclic compound GO:0071407 87 0.010
regulation of kinase activity GO:0043549 249 0.010
regulation of ossification GO:0030278 112 0.010
primary neural tube formation GO:0014020 95 0.010
negative regulation of growth GO:0045926 99 0.010
sensory perception GO:0007600 245 0.010
mrna metabolic process GO:0016071 84 0.010
response to peptide GO:1901652 136 0.010
mesenchymal cell differentiation GO:0048762 107 0.010
cell cycle checkpoint GO:0000075 47 0.010
regulation of cell cycle GO:0051726 281 0.010

Zfp281 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.036
disease of cellular proliferation DOID:14566 0 0.036
organ system cancer DOID:0050686 0 0.027
large intestine cancer DOID:5672 0 0.014
colon cancer DOID:219 0 0.014
gastrointestinal system cancer DOID:3119 0 0.014
intestinal cancer DOID:10155 0 0.014
colorectal cancer DOID:9256 0 0.014