Mus musculus

98 known processes

Intu

inturned planar cell polarity effector homolog (Drosophila)

(Aliases: Pdzk6,9430087H23Rik,mKIAA1284,9230116I04Rik,Pdzd6)

Intu biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.109
cofactor metabolic process GO:0051186 80 0.054
dna metabolic process GO:0006259 303 0.054
coenzyme metabolic process GO:0006732 52 0.052
organic cyclic compound catabolic process GO:1901361 295 0.047
organonitrogen compound catabolic process GO:1901565 264 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.044
cellular amine metabolic process GO:0044106 44 0.044
ribonucleoside metabolic process GO:0009119 245 0.043
cellular macromolecule catabolic process GO:0044265 206 0.043
forebrain development GO:0030900 302 0.041
nucleobase containing small molecule metabolic process GO:0055086 352 0.041
cellular nitrogen compound catabolic process GO:0044270 280 0.041
regulation of cellular ketone metabolic process GO:0010565 66 0.039
heterocycle catabolic process GO:0046700 280 0.039
nucleoside metabolic process GO:0009116 246 0.039
amine metabolic process GO:0009308 45 0.039
glycosyl compound metabolic process GO:1901657 246 0.038
purine ribonucleoside metabolic process GO:0046128 241 0.038
purine containing compound metabolic process GO:0072521 311 0.037
macromolecule catabolic process GO:0009057 281 0.037
male gamete generation GO:0048232 285 0.037
cellular ketone metabolic process GO:0042180 84 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
purine nucleoside metabolic process GO:0042278 241 0.034
spermatogenesis GO:0007283 284 0.033
regulation of organelle organization GO:0033043 289 0.033
anatomical structure homeostasis GO:0060249 145 0.033
organelle assembly GO:0070925 177 0.032
sulfur compound metabolic process GO:0006790 100 0.031
cellular homeostasis GO:0019725 240 0.029
transmembrane transport GO:0055085 412 0.028
camera type eye development GO:0043010 266 0.028
cation transport GO:0006812 399 0.028
response to organonitrogen compound GO:0010243 246 0.027
microtubule based process GO:0007017 236 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
regulation of cell cycle GO:0051726 281 0.026
small molecule catabolic process GO:0044282 71 0.026
spermatid development GO:0007286 108 0.026
spermatid differentiation GO:0048515 115 0.025
response to radiation GO:0009314 165 0.025
protein maturation GO:0051604 176 0.025
membrane organization GO:0061024 245 0.025
lipid homeostasis GO:0055088 63 0.025
cellularization GO:0007349 1 0.025
alpha amino acid metabolic process GO:1901605 59 0.025
regulation of membrane potential GO:0042391 192 0.025
peptidyl amino acid modification GO:0018193 336 0.025
germ cell development GO:0007281 185 0.025
regulation of neuron differentiation GO:0045664 281 0.024
multicellular organismal signaling GO:0035637 91 0.024
positive regulation of proteolysis GO:0045862 85 0.024
regulation of cellular catabolic process GO:0031329 242 0.024
epithelial tube formation GO:0072175 130 0.023
sperm individualization GO:0007291 1 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
regulation of proteolysis GO:0030162 164 0.023
regulation of cell activation GO:0050865 289 0.023
cellular lipid metabolic process GO:0044255 323 0.022
cytoplasmic transport GO:0016482 234 0.022
apoptotic signaling pathway GO:0097190 306 0.022
regulation of hydrolase activity GO:0051336 246 0.022
innate immune response GO:0045087 157 0.022
cellular response to dna damage stimulus GO:0006974 207 0.022
maintenance of location GO:0051235 89 0.022
cilium morphogenesis GO:0060271 102 0.021
cellular protein catabolic process GO:0044257 155 0.021
sensory organ morphogenesis GO:0090596 242 0.021
positive regulation of cell death GO:0010942 224 0.021
nucleotide metabolic process GO:0009117 332 0.021
ribonucleotide metabolic process GO:0009259 291 0.021
regulation of lymphocyte activation GO:0051249 240 0.021
regulation of cell projection organization GO:0031344 206 0.021
cell type specific apoptotic process GO:0097285 268 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
cellular modified amino acid metabolic process GO:0006575 63 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
tube formation GO:0035148 140 0.021
muscle cell differentiation GO:0042692 261 0.020
cation transmembrane transport GO:0098655 266 0.020
reactive oxygen species metabolic process GO:0072593 84 0.020
small gtpase mediated signal transduction GO:0007264 97 0.020
muscle tissue development GO:0060537 308 0.020
organophosphate catabolic process GO:0046434 232 0.020
aromatic compound catabolic process GO:0019439 286 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
positive regulation of apoptotic process GO:0043065 217 0.019
leukocyte differentiation GO:0002521 342 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
embryonic epithelial tube formation GO:0001838 130 0.019
response to molecule of bacterial origin GO:0002237 143 0.019
negative regulation of cell proliferation GO:0008285 296 0.019
positive regulation of protein modification process GO:0031401 299 0.019
negative regulation of immune system process GO:0002683 209 0.019
epithelial tube morphogenesis GO:0060562 303 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.018
alpha amino acid catabolic process GO:1901606 18 0.018
cellular amino acid catabolic process GO:0009063 25 0.018
response to lipopolysaccharide GO:0032496 128 0.018
ion transmembrane transport GO:0034220 361 0.018
urogenital system development GO:0001655 261 0.018
skeletal system development GO:0001501 356 0.018
sequestering of metal ion GO:0051238 19 0.018
positive regulation of nervous system development GO:0051962 221 0.018
protein processing GO:0016485 163 0.018
positive regulation of organelle organization GO:0010638 128 0.018
positive regulation of peptidase activity GO:0010952 49 0.018
neuron death GO:0070997 154 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.018
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.018
positive regulation of programmed cell death GO:0043068 218 0.017
skin development GO:0043588 220 0.017
regulation of protein localization GO:0032880 231 0.017
action potential GO:0001508 78 0.017
carbohydrate metabolic process GO:0005975 230 0.017
cellular chemical homeostasis GO:0055082 215 0.017
neural tube development GO:0021915 160 0.017
sequestering of calcium ion GO:0051208 18 0.017
positive regulation of cell development GO:0010720 237 0.017
multicellular organism growth GO:0035264 161 0.017
regulation of cell motility GO:2000145 236 0.017
neuronal action potential GO:0019228 54 0.017
respiratory system development GO:0060541 190 0.017
regulation of peptidase activity GO:0052547 96 0.017
endomembrane system organization GO:0010256 147 0.017
organelle fission GO:0048285 170 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
protein localization to organelle GO:0033365 185 0.017
regulation of homeostatic process GO:0032844 182 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
respiratory tube development GO:0030323 167 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
neural tube formation GO:0001841 108 0.016
transmission of nerve impulse GO:0019226 76 0.016
response to nutrient levels GO:0031667 109 0.016
retina development in camera type eye GO:0060041 119 0.016
organelle localization GO:0051640 179 0.016
regulation of t cell activation GO:0050863 170 0.016
cytokine production GO:0001816 319 0.016
stem cell differentiation GO:0048863 268 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
regulation of ion transport GO:0043269 215 0.016
homeostasis of number of cells GO:0048872 210 0.016
myeloid cell differentiation GO:0030099 233 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
lymphocyte differentiation GO:0030098 242 0.016
microtubule based movement GO:0007018 84 0.016
cellular ion homeostasis GO:0006873 165 0.016
regulation of cellular amine metabolic process GO:0033238 20 0.016
compound eye development GO:0048749 1 0.016
gland development GO:0048732 330 0.016
lung development GO:0030324 164 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
humoral immune response GO:0006959 57 0.016
divalent inorganic cation transport GO:0072511 178 0.016
protein ubiquitination GO:0016567 171 0.016
ras protein signal transduction GO:0007265 77 0.015
telencephalon development GO:0021537 186 0.015
carboxylic acid catabolic process GO:0046395 51 0.015
negative regulation of nervous system development GO:0051961 156 0.015
cellular response to lipid GO:0071396 145 0.015
protein oligomerization GO:0051259 67 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
t cell activation GO:0042110 289 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
appendage development GO:0048736 166 0.015
heart morphogenesis GO:0003007 178 0.015
nuclear division GO:0000280 158 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
acylglycerol homeostasis GO:0055090 16 0.015
lipid biosynthetic process GO:0008610 179 0.015
regulation of hormone levels GO:0010817 211 0.015
dendrite development GO:0016358 115 0.015
chromatin organization GO:0006325 206 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.015
primary neural tube formation GO:0014020 95 0.015
neural tube closure GO:0001843 90 0.015
positive regulation of endopeptidase activity GO:0010950 43 0.015
immune effector process GO:0002252 321 0.015
negative regulation of molecular function GO:0044092 258 0.015
nucleotide catabolic process GO:0009166 217 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
circulatory system process GO:0003013 197 0.014
oxidation reduction process GO:0055114 342 0.014
regulation of anatomical structure size GO:0090066 178 0.014
divalent metal ion transport GO:0070838 172 0.014
wnt signaling pathway GO:0016055 188 0.014
hindbrain development GO:0030902 128 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
regulation of kinase activity GO:0043549 249 0.014
regulation of apoptotic dna fragmentation GO:1902510 5 0.014
cell activation involved in immune response GO:0002263 126 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
nitrogen compound transport GO:0071705 271 0.014
rho protein signal transduction GO:0007266 32 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
actin cytoskeleton organization GO:0030036 220 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
purine containing compound catabolic process GO:0072523 213 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
organic acid catabolic process GO:0016054 51 0.014
renal system development GO:0072001 225 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
axonogenesis GO:0007409 274 0.014
cilium assembly GO:0042384 81 0.014
regulation of cytokine production GO:0001817 266 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
tissue homeostasis GO:0001894 115 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
cell adhesion GO:0007155 329 0.014
blood vessel morphogenesis GO:0048514 285 0.014
cation homeostasis GO:0055080 212 0.014
glial cell apoptotic process GO:0034349 3 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
negative regulation of cell development GO:0010721 169 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
blood circulation GO:0008015 195 0.013
regulation of protein kinase activity GO:0045859 232 0.013
regulation of cell adhesion GO:0030155 154 0.013
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.013
response to acid chemical GO:0001101 111 0.013
digestive tract development GO:0048565 190 0.013
embryonic placenta development GO:0001892 98 0.013
response to ionizing radiation GO:0010212 42 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
metal ion homeostasis GO:0055065 189 0.013
cellular response to lipopolysaccharide GO:0071222 77 0.013
b cell activation GO:0042113 161 0.013
regulation of endopeptidase activity GO:0052548 89 0.013
digestive system development GO:0055123 200 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
regulation of cell cycle process GO:0010564 160 0.013
regulation of cell growth GO:0001558 91 0.013
protein targeting GO:0006605 143 0.013
endocytosis GO:0006897 168 0.013
nucleoside catabolic process GO:0009164 206 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
chemotaxis GO:0006935 247 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
nuclear transport GO:0051169 139 0.012
regulation of actin filament based process GO:0032970 99 0.012
rhythmic process GO:0048511 174 0.012
activation of cysteine type endopeptidase activity GO:0097202 27 0.012
positive regulation of apoptotic signaling pathway GO:2001235 95 0.012
leukocyte proliferation GO:0070661 172 0.012
rna processing GO:0006396 105 0.012
regulation of cellular component size GO:0032535 121 0.012
stem cell proliferation GO:0072089 117 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
developmental maturation GO:0021700 193 0.012
response to extracellular stimulus GO:0009991 127 0.012
cellular protein complex assembly GO:0043623 116 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
adult behavior GO:0030534 135 0.012
cellular response to molecule of bacterial origin GO:0071219 83 0.012
regulation of system process GO:0044057 200 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
protein homooligomerization GO:0051260 43 0.012
lymphocyte proliferation GO:0046651 164 0.012
sensory perception GO:0007600 245 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
anion transport GO:0006820 177 0.012
inflammatory response GO:0006954 244 0.012
single organismal cell cell adhesion GO:0016337 131 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
smoothened signaling pathway GO:0007224 105 0.012
regulation of cysteine type endopeptidase activity GO:2000116 65 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
kidney development GO:0001822 213 0.012
single organism cell adhesion GO:0098602 156 0.012
dephosphorylation GO:0016311 129 0.012
calcium ion transport GO:0006816 159 0.012
regulation of neuron projection development GO:0010975 169 0.012
organic anion transport GO:0015711 137 0.012
response to inorganic substance GO:0010035 96 0.012
chromatin modification GO:0016568 187 0.012
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.011
protein catabolic process GO:0030163 221 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
regulation of secretion by cell GO:1903530 249 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
dna recombination GO:0006310 92 0.011
leukocyte migration GO:0050900 124 0.011
lateral inhibition GO:0046331 1 0.011
synapse organization GO:0050808 125 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
dna catabolic process endonucleolytic GO:0000737 15 0.011
locomotory behavior GO:0007626 195 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.011
adaptive immune response GO:0002250 155 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
muscle cell development GO:0055001 133 0.011
central nervous system morphogenesis GO:0021551 2 0.011
stem cell development GO:0048864 219 0.011
ensheathment of neurons GO:0007272 76 0.011
positive regulation of protein transport GO:0051222 93 0.011
cell division GO:0051301 120 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
regulation of intracellular transport GO:0032386 159 0.011
striated muscle tissue development GO:0014706 293 0.011
lipid localization GO:0010876 126 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
regulation of body fluid levels GO:0050878 162 0.011
leukocyte mediated immunity GO:0002443 174 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
dna repair GO:0006281 107 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
cellular response to acid chemical GO:0071229 68 0.011
positive regulation of transferase activity GO:0051347 167 0.011
positive regulation of cell activation GO:0050867 158 0.011
multi multicellular organism process GO:0044706 109 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
myeloid cell homeostasis GO:0002262 114 0.011
limb development GO:0060173 166 0.011
response to organic cyclic compound GO:0014070 198 0.011
regulation of actin cytoskeleton organization GO:0032956 84 0.010
positive regulation of immune effector process GO:0002699 107 0.010
axon ensheathment GO:0008366 76 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
translation GO:0006412 93 0.010
ribonucleoside triphosphate catabolic process GO:0009203 199 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
myelination GO:0042552 74 0.010
regulation of metal ion transport GO:0010959 106 0.010
establishment of organelle localization GO:0051656 122 0.010
phenol containing compound metabolic process GO:0018958 60 0.010
morphogenesis of a branching structure GO:0001763 203 0.010
regulation of antimicrobial humoral response GO:0002759 3 0.010
mitotic cell cycle GO:0000278 195 0.010
response to starvation GO:0042594 65 0.010
tube closure GO:0060606 91 0.010
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
gtp metabolic process GO:0046039 144 0.010
appendage morphogenesis GO:0035107 149 0.010
peptide transport GO:0015833 133 0.010
positive regulation of neuron differentiation GO:0045666 141 0.010
placenta development GO:0001890 140 0.010
regulation of carbohydrate metabolic process GO:0006109 75 0.010
regulation of leukocyte proliferation GO:0070663 121 0.010

Intu disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
sensory system disease DOID:0050155 0 0.016
central nervous system disease DOID:331 0 0.014
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.013
retinal disease DOID:5679 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012
immune system disease DOID:2914 0 0.012