Mus musculus

0 known processes

Leprot

leptin receptor overlapping transcript

(Aliases: Obrgrp,MGC6694,OB-RGRP,VPS55,LEPR)

Leprot biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carbohydrate derivative catabolic process GO:1901136 231 0.228
purine containing compound catabolic process GO:0072523 213 0.181
glycosyl compound metabolic process GO:1901657 246 0.164
positive regulation of cell death GO:0010942 224 0.142
purine nucleotide metabolic process GO:0006163 302 0.141
nucleoside metabolic process GO:0009116 246 0.128
regulation of cellular catabolic process GO:0031329 242 0.122
nucleoside phosphate metabolic process GO:0006753 338 0.120
purine nucleotide catabolic process GO:0006195 211 0.119
nucleotide catabolic process GO:0009166 217 0.115
membrane organization GO:0061024 245 0.114
aromatic compound catabolic process GO:0019439 286 0.109
ribonucleotide catabolic process GO:0009261 208 0.106
guanosine containing compound catabolic process GO:1901069 144 0.105
purine ribonucleoside metabolic process GO:0046128 241 0.103
nucleoside catabolic process GO:0009164 206 0.101
regulation of apoptotic signaling pathway GO:2001233 197 0.101
cell adhesion GO:0007155 329 0.100
guanosine containing compound metabolic process GO:1901068 144 0.100
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.097
purine nucleoside metabolic process GO:0042278 241 0.097
organophosphate catabolic process GO:0046434 232 0.094
ribonucleoside triphosphate catabolic process GO:0009203 199 0.093
positive regulation of programmed cell death GO:0043068 218 0.092
ribonucleoside catabolic process GO:0042454 206 0.091
regulation of membrane potential GO:0042391 192 0.089
negative regulation of molecular function GO:0044092 258 0.087
heterocycle catabolic process GO:0046700 280 0.085
nucleoside phosphate catabolic process GO:1901292 222 0.084
ribonucleoside triphosphate metabolic process GO:0009199 220 0.083
purine nucleoside triphosphate metabolic process GO:0009144 226 0.082
purine ribonucleotide metabolic process GO:0009150 290 0.081
regulation of cellular ketone metabolic process GO:0010565 66 0.080
nucleobase containing small molecule metabolic process GO:0055086 352 0.079
nucleoside triphosphate metabolic process GO:0009141 230 0.079
purine ribonucleoside catabolic process GO:0046130 205 0.077
purine ribonucleotide catabolic process GO:0009154 208 0.076
purine containing compound metabolic process GO:0072521 311 0.076
positive regulation of apoptotic signaling pathway GO:2001235 95 0.075
nucleotide metabolic process GO:0009117 332 0.075
cellular amino acid metabolic process GO:0006520 103 0.075
microglia differentiation GO:0014004 2 0.075
organonitrogen compound catabolic process GO:1901565 264 0.075
ribonucleotide metabolic process GO:0009259 291 0.068
positive regulation of apoptotic process GO:0043065 217 0.067
myeloid cell differentiation GO:0030099 233 0.067
ribonucleoside metabolic process GO:0009119 245 0.065
apoptotic signaling pathway GO:0097190 306 0.063
nucleoside triphosphate catabolic process GO:0009143 205 0.060
cellular nitrogen compound catabolic process GO:0044270 280 0.059
calcium ion homeostasis GO:0055074 127 0.059
regulation of transferase activity GO:0051338 263 0.059
regulation of protein transport GO:0051223 163 0.059
blood coagulation GO:0007596 76 0.058
organic cyclic compound catabolic process GO:1901361 295 0.058
regulation of cell cycle GO:0051726 281 0.057
regulation of neuron apoptotic process GO:0043523 122 0.056
cell substrate adhesion GO:0031589 130 0.055
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.054
purine nucleoside catabolic process GO:0006152 205 0.054
retrograde transport endosome to golgi GO:0042147 2 0.053
regulation of purine nucleotide metabolic process GO:1900542 169 0.053
positive regulation of b cell receptor signaling pathway GO:0050861 4 0.049
action potential GO:0001508 78 0.048
regulation of cellular amino acid metabolic process GO:0006521 5 0.048
endocytosis GO:0006897 168 0.048
regulation of cellular amine metabolic process GO:0033238 20 0.048
mitotic cell cycle process GO:1903047 159 0.047
endomembrane system organization GO:0010256 147 0.046
response to acid chemical GO:0001101 111 0.046
regulation of secretion GO:0051046 274 0.045
positive regulation of protein modification process GO:0031401 299 0.043
regulation of hydrolase activity GO:0051336 246 0.043
regulation of kinase activity GO:0043549 249 0.042
gtp metabolic process GO:0046039 144 0.041
regulation of protein localization GO:0032880 231 0.041
purine nucleoside triphosphate catabolic process GO:0009146 203 0.041
regulation of interleukin 8 secretion GO:2000482 2 0.040
positive regulation of protein phosphorylation GO:0001934 242 0.040
metal ion homeostasis GO:0055065 189 0.040
immune effector process GO:0002252 321 0.039
cell type specific apoptotic process GO:0097285 268 0.039
regulation of response to wounding GO:1903034 189 0.039
synaptic transmission GO:0007268 329 0.038
response to lipopolysaccharide GO:0032496 128 0.037
g protein coupled receptor signaling pathway GO:0007186 243 0.037
neuron apoptotic process GO:0051402 142 0.036
multicellular organismal signaling GO:0035637 91 0.036
regulation of cell motility GO:2000145 236 0.036
response to nutrient levels GO:0031667 109 0.035
cellular ketone metabolic process GO:0042180 84 0.035
inflammatory response GO:0006954 244 0.033
membrane fusion GO:0061025 38 0.033
positive regulation of protein kinase activity GO:0045860 144 0.033
gtp catabolic process GO:0006184 143 0.033
positive regulation of myeloid cell apoptotic process GO:0033034 4 0.033
dna metabolic process GO:0006259 303 0.032
cellular calcium ion homeostasis GO:0006874 119 0.032
protein localization to nucleus GO:0034504 121 0.032
ribose phosphate metabolic process GO:0019693 291 0.032
peptidyl tyrosine phosphorylation GO:0018108 143 0.032
peptidyl amino acid modification GO:0018193 336 0.032
small gtpase mediated signal transduction GO:0007264 97 0.032
cellular homeostasis GO:0019725 240 0.031
cellular chemical homeostasis GO:0055082 215 0.031
myeloid leukocyte differentiation GO:0002573 119 0.030
regulation of synaptic plasticity GO:0048167 87 0.030
intracellular protein transport GO:0006886 204 0.030
regulation of nucleotide metabolic process GO:0006140 169 0.030
plasma membrane organization GO:0007009 90 0.030
regulation of neuron death GO:1901214 134 0.030
cellular response to dna damage stimulus GO:0006974 207 0.030
regulation of purine nucleotide catabolic process GO:0033121 122 0.030
leukocyte differentiation GO:0002521 342 0.029
fibrinolysis GO:0042730 3 0.029
regulation of cell adhesion GO:0030155 154 0.029
positive regulation of cell adhesion GO:0045785 80 0.029
protein processing GO:0016485 163 0.029
macromolecule catabolic process GO:0009057 281 0.029
positive regulation of hydrolase activity GO:0051345 148 0.028
regulation of nucleoside metabolic process GO:0009118 130 0.028
transmembrane transport GO:0055085 412 0.028
peptidyl tyrosine modification GO:0018212 145 0.026
single fertilization GO:0007338 82 0.026
establishment of vesicle localization GO:0051650 81 0.026
transmission of nerve impulse GO:0019226 76 0.026
cellular amine metabolic process GO:0044106 44 0.026
coagulation GO:0050817 78 0.026
heart process GO:0003015 94 0.026
male gamete generation GO:0048232 285 0.025
regulation of vesicle mediated transport GO:0060627 139 0.025
neuron death GO:0070997 154 0.025
negative regulation of neuron death GO:1901215 98 0.025
phagosome maturation GO:0090382 4 0.025
hemostasis GO:0007599 78 0.025
leukocyte apoptotic process GO:0071887 71 0.025
regulation of neuron projection development GO:0010975 169 0.025
positive regulation of neutrophil apoptotic process GO:0033031 1 0.025
cation transmembrane transport GO:0098655 266 0.025
regulation of body fluid levels GO:0050878 162 0.025
cation homeostasis GO:0055080 212 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.024
muscle tissue development GO:0060537 308 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
regulation of binding GO:0051098 111 0.024
positive regulation of nucleotide metabolic process GO:0045981 114 0.024
macrophage differentiation GO:0030225 20 0.024
microtubule based process GO:0007017 236 0.023
regulation of protein binding GO:0043393 60 0.023
sensory perception GO:0007600 245 0.023
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.023
response to extracellular stimulus GO:0009991 127 0.023
innate immune response GO:0045087 157 0.023
cellular response to organonitrogen compound GO:0071417 145 0.022
negative regulation of neuron apoptotic process GO:0043524 92 0.022
negative regulation of cell proliferation GO:0008285 296 0.022
wound healing GO:0042060 157 0.022
development of primary sexual characteristics GO:0045137 143 0.022
positive regulation of antigen receptor mediated signaling pathway GO:0050857 9 0.022
regulation of cell projection organization GO:0031344 206 0.022
axon ensheathment GO:0008366 76 0.022
regulation of secretion by cell GO:1903530 249 0.022
amine metabolic process GO:0009308 45 0.021
protein localization to plasma membrane GO:0072659 57 0.021
microglia development GO:0014005 2 0.021
regulation of protein kinase activity GO:0045859 232 0.021
cellular divalent inorganic cation homeostasis GO:0072503 127 0.021
regulation of protein serine threonine kinase activity GO:0071900 157 0.021
vacuole organization GO:0007033 38 0.020
cellular response to acid chemical GO:0071229 68 0.020
intrinsic apoptotic signaling pathway GO:0097193 132 0.020
response to starvation GO:0042594 65 0.020
positive regulation of transferase activity GO:0051347 167 0.020
response to molecule of bacterial origin GO:0002237 143 0.020
regulation of nucleotide catabolic process GO:0030811 122 0.020
myelination GO:0042552 74 0.020
muscle contraction GO:0006936 101 0.020
protein maturation GO:0051604 176 0.020
cellular response to lipid GO:0071396 145 0.020
striated muscle tissue development GO:0014706 293 0.020
positive regulation of nervous system development GO:0051962 221 0.020
regulation of establishment of protein localization GO:0070201 181 0.020
positive regulation of gtp catabolic process GO:0033126 85 0.019
positive regulation of cell development GO:0010720 237 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.019
multi multicellular organism process GO:0044706 109 0.019
response to peptide hormone GO:0043434 127 0.019
divalent inorganic cation transport GO:0072511 178 0.019
response to organic cyclic compound GO:0014070 198 0.019
regulation of protein maturation GO:1903317 96 0.019
sequestering of calcium ion GO:0051208 18 0.019
asymmetric stem cell division GO:0098722 3 0.019
regulation of system process GO:0044057 200 0.019
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.019
cellular response to cytokine stimulus GO:0071345 189 0.019
positive regulation of cellular catabolic process GO:0031331 148 0.019
apoptotic cell clearance GO:0043277 17 0.018
regulation of interleukin 8 production GO:0032677 3 0.018
fertilization GO:0009566 127 0.018
organelle fusion GO:0048284 28 0.018
positive regulation of interleukin 1 alpha production GO:0032730 4 0.018
leukocyte mediated immunity GO:0002443 174 0.018
positive regulation of secretion GO:0051047 130 0.018
regulation of inflammatory response GO:0050727 147 0.018
divalent metal ion transport GO:0070838 172 0.018
homeostasis of number of cells GO:0048872 210 0.018
positive regulation of gtpase activity GO:0043547 85 0.018
regulation of gtp catabolic process GO:0033124 113 0.018
lymphocyte apoptotic process GO:0070227 54 0.018
carbohydrate homeostasis GO:0033500 128 0.018
response to endoplasmic reticulum stress GO:0034976 53 0.018
cytoplasmic transport GO:0016482 234 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
organophosphate biosynthetic process GO:0090407 122 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
adult behavior GO:0030534 135 0.018
t cell activation GO:0042110 289 0.018
cellular macromolecule catabolic process GO:0044265 206 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
response to organonitrogen compound GO:0010243 246 0.017
cellular ion homeostasis GO:0006873 165 0.017
regulation of t cell activation GO:0050863 170 0.017
cellular metal ion homeostasis GO:0006875 151 0.017
regulation of intracellular transport GO:0032386 159 0.017
calcium ion transport GO:0006816 159 0.017
ion transmembrane transport GO:0034220 361 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
positive regulation of nucleotide catabolic process GO:0030813 88 0.017
cardiac muscle contraction GO:0060048 32 0.017
heart contraction GO:0060047 93 0.017
skeletal system development GO:0001501 356 0.017
establishment or maintenance of cell polarity GO:0007163 86 0.017
positive regulation of intracellular transport GO:0032388 70 0.017
regulation of muscle tissue development GO:1901861 97 0.017
positive regulation of neuron projection development GO:0010976 79 0.016
phagolysosome assembly GO:0001845 3 0.016
cognition GO:0050890 149 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
negative regulation of apoptotic signaling pathway GO:2001234 104 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.016
spermatogenesis GO:0007283 284 0.016
cellular response to molecule of bacterial origin GO:0071219 83 0.016
establishment of organelle localization GO:0051656 122 0.016
angiogenesis GO:0001525 201 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
blood circulation GO:0008015 195 0.016
cell fate commitment GO:0045165 210 0.016
lymphocyte mediated immunity GO:0002449 139 0.016
cellular response to external stimulus GO:0071496 88 0.016
cell cell junction organization GO:0045216 72 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
mitotic cell cycle GO:0000278 195 0.016
zymogen activation GO:0031638 41 0.016
blood vessel morphogenesis GO:0048514 285 0.016
response to growth factor GO:0070848 198 0.016
sequestering of metal ion GO:0051238 19 0.015
cellular response to starvation GO:0009267 57 0.015
exocytosis GO:0006887 121 0.015
sensory perception of taste GO:0050909 18 0.015
cellular protein complex assembly GO:0043623 116 0.015
protein catabolic process GO:0030163 221 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
regulation of lymphocyte apoptotic process GO:0070228 41 0.015
interleukin 1 alpha secretion GO:0050703 3 0.015
gland development GO:0048732 330 0.015
positive regulation of protein transport GO:0051222 93 0.015
sensory organ morphogenesis GO:0090596 242 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.015
regulation of homeostatic process GO:0032844 182 0.015
acute inflammatory response GO:0002526 41 0.015
positive regulation of kinase activity GO:0033674 155 0.015
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
synaptic vesicle localization GO:0097479 59 0.015
muscle fiber development GO:0048747 76 0.015
maintenance of location GO:0051235 89 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
muscle cell differentiation GO:0042692 261 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
stem cell differentiation GO:0048863 268 0.014
regulation of interleukin 1 alpha production GO:0032650 4 0.014
regulation of cell activation GO:0050865 289 0.014
positive regulation of podosome assembly GO:0071803 3 0.014
negative regulation of actin filament depolymerization GO:0030835 9 0.014
protein localization to membrane GO:0072657 108 0.014
negative regulation of cell activation GO:0050866 111 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
calcium ion dependent exocytosis GO:0017156 35 0.014
t cell apoptotic process GO:0070231 39 0.014
positive regulation of homeostatic process GO:0032846 64 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
cellularization GO:0007349 1 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.013
neuromuscular process GO:0050905 99 0.013
neuronal action potential GO:0019228 54 0.013
regulation of voltage gated calcium channel activity GO:1901385 4 0.013
wnt signaling pathway GO:0016055 188 0.013
negative regulation of calcium ion transmembrane transporter activity GO:1901020 1 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
tissue homeostasis GO:0001894 115 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.013
ensheathment of neurons GO:0007272 76 0.013
sensory system development GO:0048880 3 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
response to inorganic substance GO:0010035 96 0.013
amide transport GO:0042886 138 0.013
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
response to water GO:0009415 1 0.013
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.013
regulation of cellular response to growth factor stimulus GO:0090287 82 0.013
regulation of synapse structural plasticity GO:0051823 4 0.013
protein localization to organelle GO:0033365 185 0.013
developmental maturation GO:0021700 193 0.013
regulation of striated muscle cell differentiation GO:0051153 81 0.013
regulation of protein secretion GO:0050708 82 0.013
positive regulation of mitotic cell cycle GO:0045931 41 0.012
glial cell differentiation GO:0010001 131 0.012
nitrogen compound transport GO:0071705 271 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
response to peptide GO:1901652 136 0.012
regulation of b cell activation GO:0050864 81 0.012
positive regulation of protein export from nucleus GO:0046827 4 0.012
regulation of organelle organization GO:0033043 289 0.012
tissue remodeling GO:0048771 102 0.012
glial cell development GO:0021782 54 0.012
synaptic vesicle transport GO:0048489 57 0.012
protein targeting GO:0006605 143 0.012
vesicle organization GO:0016050 60 0.012
regulation of wound healing GO:0061041 40 0.012
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.012
regulation of mapk cascade GO:0043408 248 0.012
gonad development GO:0008406 141 0.012
regulation of cell substrate adhesion GO:0010810 73 0.012
leukocyte migration GO:0050900 124 0.012
response to thyroid hormone GO:0097066 2 0.012
glial cell apoptotic process GO:0034349 3 0.012
formation of organ boundary GO:0010160 1 0.012
negative regulation of binding GO:0051100 39 0.012
signal transduction in absence of ligand GO:0038034 55 0.012
lymphocyte differentiation GO:0030098 242 0.012
positive regulation of cell migration GO:0030335 109 0.012
negative regulation of immune system process GO:0002683 209 0.012
neural tube development GO:0021915 160 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
regulation of neuron differentiation GO:0045664 281 0.011
camera type eye development GO:0043010 266 0.011
cellular lipid metabolic process GO:0044255 323 0.011
regulation of skeletal muscle fiber development GO:0048742 36 0.011
cardiac muscle cell contraction GO:0086003 7 0.011
regulation of coagulation GO:0050818 31 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
myeloid cell homeostasis GO:0002262 114 0.011
activation of adenylate cyclase activity GO:0007190 4 0.011
negative regulation of cation channel activity GO:2001258 1 0.011
establishment of tissue polarity GO:0007164 28 0.011
regulation of cell cycle process GO:0010564 160 0.011
neurotransmitter secretion GO:0007269 62 0.011
regulation of defense response GO:0031347 233 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
establishment of protein localization to plasma membrane GO:0090002 34 0.011
response to light stimulus GO:0009416 135 0.011
digestive system development GO:0055123 200 0.011
organelle localization GO:0051640 179 0.011
mapk cascade GO:0000165 281 0.011
cytokine secretion GO:0050663 72 0.011
regulation of neurotransmitter levels GO:0001505 87 0.011
regulation of protein catabolic process GO:0042176 108 0.011
positive regulation of neuron death GO:1901216 28 0.011
defense response to virus GO:0051607 68 0.011
regulation of multi organism process GO:0043900 111 0.011
sensory perception of chemical stimulus GO:0007606 51 0.011
regulation of muscle system process GO:0090257 80 0.011
viral gene expression GO:0019080 3 0.011
regulation of neutrophil apoptotic process GO:0033029 1 0.011
regulated secretory pathway GO:0045055 32 0.011
regulation of interleukin 1 alpha secretion GO:0050705 3 0.011
t cell mediated immunity GO:0002456 50 0.011
cellular response to extracellular stimulus GO:0031668 81 0.011
male sex differentiation GO:0046661 109 0.011
multicellular organismal homeostasis GO:0048871 164 0.010
extracellular structure organization GO:0043062 148 0.010
regulation of mitotic cell cycle phase transition GO:1901990 73 0.010
ras protein signal transduction GO:0007265 77 0.010
regulation of plasminogen activation GO:0010755 4 0.010
regulation of heart contraction GO:0008016 77 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.010
morphogenesis of a branching epithelium GO:0061138 193 0.010
negative regulation of necroptotic process GO:0060546 9 0.010
cell killing GO:0001906 67 0.010
negative regulation of protein modification process GO:0031400 163 0.010
cell junction organization GO:0034330 77 0.010
lateral inhibition GO:0046331 1 0.010
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.010

Leprot disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.057
lysosomal storage disease DOID:3211 0 0.057
inherited metabolic disorder DOID:655 0 0.057
disease of anatomical entity DOID:7 0 0.039
nervous system disease DOID:863 0 0.039
lipid storage disease DOID:9455 0 0.017