Mus musculus

41 known processes

Nisch

nischarin

(Aliases: I-1,3202002H23Rik,1200007D05Rik,AW494485)

Nisch biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gene silencing by mirna GO:0035195 10 0.276
small gtpase mediated signal transduction GO:0007264 97 0.234
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.228
regulation of purine nucleotide metabolic process GO:1900542 169 0.227
purine containing compound metabolic process GO:0072521 311 0.221
ribonucleoside catabolic process GO:0042454 206 0.203
purine nucleoside metabolic process GO:0042278 241 0.203
regulation of nucleotide metabolic process GO:0006140 169 0.192
purine nucleoside triphosphate metabolic process GO:0009144 226 0.184
amine metabolic process GO:0009308 45 0.181
purine containing compound catabolic process GO:0072523 213 0.180
glycosyl compound catabolic process GO:1901658 206 0.179
gtp metabolic process GO:0046039 144 0.174
ribonucleotide metabolic process GO:0009259 291 0.164
ribonucleotide catabolic process GO:0009261 208 0.147
nucleobase containing small molecule metabolic process GO:0055086 352 0.131
purine ribonucleotide catabolic process GO:0009154 208 0.129
aromatic compound catabolic process GO:0019439 286 0.129
nucleoside catabolic process GO:0009164 206 0.127
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.120
cellular nitrogen compound catabolic process GO:0044270 280 0.115
regulation of cellular catabolic process GO:0031329 242 0.112
macromolecule catabolic process GO:0009057 281 0.109
organonitrogen compound catabolic process GO:1901565 264 0.108
digestive system development GO:0055123 200 0.108
nucleoside phosphate metabolic process GO:0006753 338 0.104
ribonucleoside metabolic process GO:0009119 245 0.099
purine nucleotide metabolic process GO:0006163 302 0.099
glycosyl compound metabolic process GO:1901657 246 0.095
nucleoside metabolic process GO:0009116 246 0.094
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.091
vesicle localization GO:0051648 86 0.091
regulation of cellular amino acid metabolic process GO:0006521 5 0.086
ribose phosphate metabolic process GO:0019693 291 0.086
regulation of nucleotide catabolic process GO:0030811 122 0.084
stem cell fate specification GO:0048866 3 0.084
nucleoside triphosphate catabolic process GO:0009143 205 0.081
regulation of purine nucleotide catabolic process GO:0033121 122 0.081
positive regulation of dna templated transcription elongation GO:0032786 2 0.081
positive regulation of gtp catabolic process GO:0033126 85 0.080
dna metabolic process GO:0006259 303 0.079
ribonucleoside triphosphate metabolic process GO:0009199 220 0.079
regulation of gtp catabolic process GO:0033124 113 0.079
regulation of cellular ketone metabolic process GO:0010565 66 0.073
leukocyte differentiation GO:0002521 342 0.072
cellular ketone metabolic process GO:0042180 84 0.071
gene silencing by rna GO:0031047 19 0.070
epithalamus development GO:0021538 2 0.068
intracellular protein transport GO:0006886 204 0.067
cytoplasmic transport GO:0016482 234 0.066
regulation of defense response GO:0031347 233 0.065
purine nucleotide catabolic process GO:0006195 211 0.064
purine nucleoside catabolic process GO:0006152 205 0.064
heterocycle catabolic process GO:0046700 280 0.063
protein targeting GO:0006605 143 0.063
ras protein signal transduction GO:0007265 77 0.061
purine ribonucleoside metabolic process GO:0046128 241 0.061
cellular amine metabolic process GO:0044106 44 0.060
ribonucleoside monophosphate metabolic process GO:0009161 80 0.060
negative regulation of protein metabolic process GO:0051248 282 0.060
nucleotide catabolic process GO:0009166 217 0.060
homeostasis of number of cells GO:0048872 210 0.059
carbohydrate derivative catabolic process GO:1901136 231 0.057
male gamete generation GO:0048232 285 0.057
organic cyclic compound catabolic process GO:1901361 295 0.057
rho protein signal transduction GO:0007266 32 0.056
skeletal system morphogenesis GO:0048705 203 0.056
guanosine containing compound metabolic process GO:1901068 144 0.054
regulation of cellular amine metabolic process GO:0033238 20 0.054
regulation of cell motility GO:2000145 236 0.053
nucleoside triphosphate metabolic process GO:0009141 230 0.053
positive regulation of gtpase activity GO:0043547 85 0.052
purine ribonucleoside catabolic process GO:0046130 205 0.052
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.052
cellular amino acid metabolic process GO:0006520 103 0.051
establishment of vesicle localization GO:0051650 81 0.049
positive regulation of binding GO:0051099 49 0.049
exocytosis GO:0006887 121 0.049
negative regulation of synapse assembly GO:0051964 3 0.048
nucleoside phosphate catabolic process GO:1901292 222 0.047
negative regulation of phosphorus metabolic process GO:0010563 184 0.047
regulation of organelle organization GO:0033043 289 0.046
nucleotide metabolic process GO:0009117 332 0.046
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.046
epithelial cell proliferation GO:0050673 174 0.045
negative regulation of phosphate metabolic process GO:0045936 184 0.044
habenula development GO:0021986 2 0.044
organophosphate catabolic process GO:0046434 232 0.044
purine ribonucleotide metabolic process GO:0009150 290 0.043
negative regulation of nervous system development GO:0051961 156 0.042
guanosine containing compound catabolic process GO:1901069 144 0.042
action potential GO:0001508 78 0.041
epithelial tube morphogenesis GO:0060562 303 0.039
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.039
dna methylation GO:0006306 43 0.038
regulation of hydrolase activity GO:0051336 246 0.038
regulation of anatomical structure size GO:0090066 178 0.038
regulation of binding GO:0051098 111 0.037
neuroblast fate commitment GO:0014017 1 0.035
regulation of cytoskeleton organization GO:0051493 122 0.035
t cell activation GO:0042110 289 0.034
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.034
cellular response to dna damage stimulus GO:0006974 207 0.034
negative regulation of molecular function GO:0044092 258 0.034
regulation of mapk cascade GO:0043408 248 0.033
regulation of cellular response to stress GO:0080135 159 0.033
purine nucleoside triphosphate catabolic process GO:0009146 203 0.033
membrane organization GO:0061024 245 0.033
regulation of nucleoside metabolic process GO:0009118 130 0.032
synaptic vesicle localization GO:0097479 59 0.031
positive regulation of protein phosphorylation GO:0001934 242 0.031
compound eye development GO:0048749 1 0.031
germ cell development GO:0007281 185 0.030
gtp catabolic process GO:0006184 143 0.029
regulation of cell cycle process GO:0010564 160 0.029
cellular transition metal ion homeostasis GO:0046916 32 0.029
positive regulation of mapk cascade GO:0043410 170 0.029
regulation of intracellular transport GO:0032386 159 0.028
regulation of cell migration GO:0030334 219 0.028
positive regulation of nucleoside metabolic process GO:0045979 91 0.028
neuronal action potential GO:0019228 54 0.028
regulation of neuron differentiation GO:0045664 281 0.028
neuromuscular process GO:0050905 99 0.027
ribonucleoside triphosphate catabolic process GO:0009203 199 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.027
positive regulation of cellular catabolic process GO:0031331 148 0.027
spermatogenesis GO:0007283 284 0.027
ion transmembrane transport GO:0034220 361 0.027
learning or memory GO:0007611 148 0.026
positive regulation of nervous system development GO:0051962 221 0.026
regulation of ras protein signal transduction GO:0046578 114 0.026
establishment of protein localization to organelle GO:0072594 118 0.026
establishment of synaptic vesicle localization GO:0097480 57 0.026
regulation of cellular component biogenesis GO:0044087 181 0.026
synapse organization GO:0050808 125 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
positive regulation of mammary gland epithelial cell proliferation GO:0033601 5 0.025
negative regulation of growth GO:0045926 99 0.025
segmentation GO:0035282 93 0.025
digestive tract development GO:0048565 190 0.025
meiotic nuclear division GO:0007126 115 0.024
cytoplasmic mrna processing body assembly GO:0033962 6 0.024
regulation of protein localization GO:0032880 231 0.024
muscle tissue development GO:0060537 308 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.024
myeloid leukocyte differentiation GO:0002573 119 0.024
synaptic transmission GO:0007268 329 0.024
Rat
retrograde transport endosome to golgi GO:0042147 2 0.024
neuroblast differentiation GO:0014016 2 0.024
sequestering of metal ion GO:0051238 19 0.023
regionalization GO:0003002 337 0.023
positive regulation of hydrolase activity GO:0051345 148 0.023
renal system development GO:0072001 225 0.023
kidney development GO:0001822 213 0.023
organelle localization GO:0051640 179 0.023
hindbrain development GO:0030902 128 0.023
dna alkylation GO:0006305 43 0.023
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.022
regulation of reactive oxygen species metabolic process GO:2000377 40 0.022
canonical wnt signaling pathway GO:0060070 130 0.022
anion transport GO:0006820 177 0.022
regulation of ras gtpase activity GO:0032318 88 0.022
mitotic cell cycle process GO:1903047 159 0.022
reactive oxygen species metabolic process GO:0072593 84 0.021
cellular macromolecule catabolic process GO:0044265 206 0.021
forebrain development GO:0030900 302 0.021
regulation of actin nucleation GO:0051125 4 0.021
regulation of transferase activity GO:0051338 263 0.021
positive regulation of leukocyte differentiation GO:1902107 86 0.021
protein import into nucleus GO:0006606 95 0.021
ameboidal type cell migration GO:0001667 128 0.021
actin cytoskeleton organization GO:0030036 220 0.021
positive regulation of protein binding GO:0032092 29 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.020
cerebellum development GO:0021549 77 0.020
cerebellar purkinje cell layer morphogenesis GO:0021692 14 0.020
epithelial cell migration GO:0010631 63 0.020
nucleocytoplasmic transport GO:0006913 139 0.020
skeletal muscle organ development GO:0060538 163 0.020
regulation of protein binding GO:0043393 60 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.019
skeletal system development GO:0001501 356 0.019
somitogenesis GO:0001756 69 0.019
cellular homeostasis GO:0019725 240 0.019
entry into host GO:0044409 15 0.019
negative regulation of gene silencing GO:0060969 2 0.019
regulation of cell activation GO:0050865 289 0.019
diencephalon development GO:0021536 63 0.018
chromatin modification GO:0016568 187 0.018
mitotic cell cycle GO:0000278 195 0.018
nephron epithelium development GO:0072009 92 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.018
mrna metabolic process GO:0016071 84 0.018
protein catabolic process GO:0030163 221 0.018
developmental maturation GO:0021700 193 0.018
axonogenesis GO:0007409 274 0.018
nephron development GO:0072006 109 0.018
single organism nuclear import GO:1902593 95 0.018
wnt signaling pathway GO:0016055 188 0.018
t cell differentiation GO:0030217 174 0.018
positive regulation of ras gtpase activity GO:0032320 65 0.018
regulation of membrane potential GO:0042391 192 0.017
regulation of engulfment of apoptotic cell GO:1901074 2 0.017
regulation of bmp signaling pathway GO:0030510 60 0.017
stem cell maintenance GO:0019827 130 0.017
ossification GO:0001503 216 0.017
rna interference GO:0016246 2 0.017
embryonic organ morphogenesis GO:0048562 276 0.017
neuron neuron synaptic transmission GO:0007270 69 0.017
Rat
cellular response to alkaline ph GO:0071469 1 0.017
regulation of protein transport GO:0051223 163 0.017
lung development GO:0030324 164 0.017
negative regulation of wnt signaling pathway GO:0030178 73 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
axis elongation involved in somitogenesis GO:0090245 4 0.017
cation transmembrane transport GO:0098655 266 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.017
tube closure GO:0060606 91 0.017
positive regulation of t cell activation GO:0050870 101 0.017
response to acid chemical GO:0001101 111 0.017
cognition GO:0050890 149 0.016
negative regulation of cell development GO:0010721 169 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
somite development GO:0061053 81 0.016
regulation of protein processing GO:0070613 96 0.016
establishment of meiotic spindle orientation GO:0051296 1 0.016
establishment of organelle localization GO:0051656 122 0.016
i kappab kinase nf kappab signaling GO:0007249 85 0.016
cartilage development GO:0051216 140 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
regulation of t cell activation GO:0050863 170 0.016
organelle fission GO:0048285 170 0.016
urogenital system development GO:0001655 261 0.016
dendrite development GO:0016358 115 0.016
regulation of map kinase activity GO:0043405 120 0.016
regulation of schwann cell proliferation GO:0010624 2 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
mapk cascade GO:0000165 281 0.016
synaptic vesicle transport GO:0048489 57 0.016
embryonic limb morphogenesis GO:0030326 126 0.016
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.016
protein processing GO:0016485 163 0.016
blood vessel morphogenesis GO:0048514 285 0.016
regulation of cytokine production GO:0001817 266 0.016
nuclear transport GO:0051169 139 0.016
regulation of rho protein signal transduction GO:0035023 71 0.016
chemotaxis GO:0006935 247 0.016
sensory organ morphogenesis GO:0090596 242 0.015
positive regulation of rho gtpase activity GO:0032321 41 0.015
negative regulation of mapk cascade GO:0043409 65 0.015
establishment or maintenance of cell polarity GO:0007163 86 0.015
positive regulation of cellular component biogenesis GO:0044089 94 0.015
actin filament polymerization GO:0030041 44 0.015
myeloid cell homeostasis GO:0002262 114 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
primary neural tube formation GO:0014020 95 0.015
cell cell junction organization GO:0045216 72 0.015
regulation of myeloid leukocyte differentiation GO:0002761 58 0.015
myeloid cell differentiation GO:0030099 233 0.015
oxidation reduction process GO:0055114 342 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.014
single fertilization GO:0007338 82 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
regulation of cell projection organization GO:0031344 206 0.014
dna modification GO:0006304 50 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
microtubule based movement GO:0007018 84 0.014
wound healing GO:0042060 157 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.014
neuron projection guidance GO:0097485 141 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
protein import GO:0017038 101 0.014
gland development GO:0048732 330 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
positive regulation of transferase activity GO:0051347 167 0.014
regulation of kinase activity GO:0043549 249 0.013
cellular chemical homeostasis GO:0055082 215 0.013
metencephalon development GO:0022037 89 0.013
regulation of homeostatic process GO:0032844 182 0.013
cell growth GO:0016049 130 0.013
midgut development GO:0007494 4 0.013
cerebellum morphogenesis GO:0021587 42 0.013
methylation GO:0032259 134 0.013
pigment accumulation GO:0043476 1 0.013
microtubule based process GO:0007017 236 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
cardiac right atrium morphogenesis GO:0003213 3 0.013
axon ensheathment GO:0008366 76 0.013
modification dependent macromolecule catabolic process GO:0043632 133 0.013
positive regulation of cell activation GO:0050867 158 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
positive regulation of kinase activity GO:0033674 155 0.013
rhombomere morphogenesis GO:0021593 2 0.013
cellular lipid metabolic process GO:0044255 323 0.013
endocytosis GO:0006897 168 0.013
hindbrain morphogenesis GO:0021575 46 0.013
gastrulation GO:0007369 116 0.013
appendage morphogenesis GO:0035107 149 0.013
positive regulation of cell death GO:0010942 224 0.012
rhythmic process GO:0048511 174 0.012
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
neuron migration GO:0001764 122 0.012
t cell proliferation GO:0042098 120 0.012
glial cell differentiation GO:0010001 131 0.012
histone lysine methylation GO:0034968 50 0.012
pteridine containing compound metabolic process GO:0042558 5 0.012
endoderm development GO:0007492 45 0.012
positive regulation of protein modification process GO:0031401 299 0.012
rna processing GO:0006396 105 0.012
respiratory tube development GO:0030323 167 0.012
negative regulation of intracellular protein transport GO:0090317 27 0.012
fertilization GO:0009566 127 0.012
oligodendrocyte differentiation GO:0048709 53 0.012
cellular response to acidic ph GO:0071468 4 0.012
stem cell differentiation GO:0048863 268 0.012
metanephric loop of henle development GO:0072236 4 0.012
regulation of organ morphogenesis GO:2000027 144 0.012
viral gene expression GO:0019080 3 0.012
negative regulation of protein maturation GO:1903318 79 0.012
regulation of endodermal cell differentiation GO:1903224 2 0.012
habituation GO:0046959 3 0.012
negative regulation of bmp signaling pathway GO:0030514 35 0.012
regulation of cellular component size GO:0032535 121 0.012
histone acetylation GO:0016573 41 0.012
digestive tract morphogenesis GO:0048546 147 0.012
mesenchyme development GO:0060485 152 0.012
regulation of protein complex assembly GO:0043254 83 0.012
plasma membrane organization GO:0007009 90 0.012
response to inorganic substance GO:0010035 96 0.012
positive regulation of cell development GO:0010720 237 0.012
neural tube development GO:0021915 160 0.012
histone h3 k4 trimethylation GO:0080182 5 0.011
cytoskeleton dependent intracellular transport GO:0030705 50 0.011
regulation of phospholipase a2 activity GO:0032429 3 0.011
epithelial cell development GO:0002064 159 0.011
regulation of system process GO:0044057 200 0.011
regulation of protein catabolic process GO:0042176 108 0.011
cation homeostasis GO:0055080 212 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
multicellular organismal signaling GO:0035637 91 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.011
cell recognition GO:0008037 83 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
cerebellar cortex formation GO:0021697 22 0.011
negative regulation of protein catabolic process GO:0042177 36 0.011
cerebral cortex development GO:0021987 86 0.011
regulation of rho gtpase activity GO:0032319 58 0.011
learning GO:0007612 98 0.011
striated muscle tissue development GO:0014706 293 0.011
stress activated mapk cascade GO:0051403 80 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
meiotic cell cycle process GO:1903046 77 0.011
nitrogen compound transport GO:0071705 271 0.011
Rat
cell migration involved in gastrulation GO:0042074 13 0.011
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.011
apoptotic signaling pathway GO:0097190 306 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
terminal button organization GO:0072553 3 0.011
developmental cell growth GO:0048588 84 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
response to retinoic acid GO:0032526 56 0.011
adult locomotory behavior GO:0008344 91 0.011
cellular response to acid chemical GO:0071229 68 0.011
cerebellar granule cell precursor tangential migration GO:0021935 1 0.011
lung epithelium development GO:0060428 37 0.011
lung cell differentiation GO:0060479 30 0.011
central nervous system neuron development GO:0021954 67 0.011
glycerophospholipid biosynthetic process GO:0046474 32 0.011
ear development GO:0043583 200 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
cell chemotaxis GO:0060326 81 0.011
intra golgi vesicle mediated transport GO:0006891 1 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
respiratory system development GO:0060541 190 0.010
actin polymerization or depolymerization GO:0008154 54 0.010
extracellular structure organization GO:0043062 148 0.010
protein localization to membrane GO:0072657 108 0.010
peptidyl amino acid modification GO:0018193 336 0.010
tissue migration GO:0090130 68 0.010
transmission of nerve impulse GO:0019226 76 0.010
maintenance of location GO:0051235 89 0.010
negative regulation of protein modification process GO:0031400 163 0.010
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.010
regulation of protein kinase activity GO:0045859 232 0.010
carbohydrate homeostasis GO:0033500 128 0.010
interleukin 8 production GO:0032637 4 0.010
protein acylation GO:0043543 64 0.010
jak stat cascade GO:0007259 42 0.010
positive regulation of organelle organization GO:0010638 128 0.010
ribonucleoside monophosphate catabolic process GO:0009158 57 0.010

Nisch disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 0 0.116
disease of anatomical entity DOID:7 0 0.116
nervous system disease DOID:863 0 0.116
neuropathy DOID:870 0 0.116
charcot marie tooth disease DOID:10595 0 0.069
immune system disease DOID:2914 0 0.017
disease of mental health DOID:150 0 0.016
non syndromic intellectual disability DOID:0050889 0 0.016
developmental disorder of mental health DOID:0060037 0 0.016
specific developmental disorder DOID:0060038 0 0.016
intellectual disability DOID:1059 0 0.016
x linked disease DOID:0050735 0 0.012