Mus musculus

0 known processes

Gpt2

glutamic pyruvate transaminase (alanine aminotransferase) 2

(Aliases: C87201,4631422C05Rik,AU041193,ALT2,AU014768)

Gpt2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.139
cellular amine metabolic process GO:0044106 44 0.061
amine metabolic process GO:0009308 45 0.059
nucleobase containing small molecule metabolic process GO:0055086 352 0.055
regulation of cellular amino acid metabolic process GO:0006521 5 0.052
cellular ketone metabolic process GO:0042180 84 0.049
ribonucleoside metabolic process GO:0009119 245 0.049
cellular lipid metabolic process GO:0044255 323 0.049
regulation of cellular amine metabolic process GO:0033238 20 0.048
regulation of cellular ketone metabolic process GO:0010565 66 0.047
oxidation reduction process GO:0055114 342 0.047
organonitrogen compound catabolic process GO:1901565 264 0.047
transmembrane transport GO:0055085 412 0.044
organonitrogen compound biosynthetic process GO:1901566 192 0.043
purine ribonucleotide metabolic process GO:0009150 290 0.041
nucleoside phosphate metabolic process GO:0006753 338 0.040
apoptotic signaling pathway GO:0097190 306 0.039
nucleotide metabolic process GO:0009117 332 0.038
response to organonitrogen compound GO:0010243 246 0.038
cation transport GO:0006812 399 0.037
purine nucleoside metabolic process GO:0042278 241 0.036
nucleoside triphosphate metabolic process GO:0009141 230 0.036
purine containing compound metabolic process GO:0072521 311 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.034
ribose phosphate metabolic process GO:0019693 291 0.034
organic cyclic compound catabolic process GO:1901361 295 0.034
heterocycle catabolic process GO:0046700 280 0.034
male gamete generation GO:0048232 285 0.034
macromolecule catabolic process GO:0009057 281 0.034
purine nucleotide metabolic process GO:0006163 302 0.033
aromatic compound catabolic process GO:0019439 286 0.033
carbohydrate metabolic process GO:0005975 230 0.033
regulation of apoptotic signaling pathway GO:2001233 197 0.033
spermatogenesis GO:0007283 284 0.032
nitrogen compound transport GO:0071705 271 0.031
cellular nitrogen compound catabolic process GO:0044270 280 0.031
purine ribonucleoside metabolic process GO:0046128 241 0.031
cellular amino acid catabolic process GO:0009063 25 0.031
regulation of organelle organization GO:0033043 289 0.030
glycosyl compound metabolic process GO:1901657 246 0.029
ion transmembrane transport GO:0034220 361 0.029
ribonucleotide metabolic process GO:0009259 291 0.029
coenzyme metabolic process GO:0006732 52 0.028
organic acid catabolic process GO:0016054 51 0.028
carbohydrate derivative biosynthetic process GO:1901137 183 0.028
purine nucleoside triphosphate metabolic process GO:0009144 226 0.027
lipid biosynthetic process GO:0008610 179 0.027
monocarboxylic acid metabolic process GO:0032787 191 0.027
cellular macromolecule catabolic process GO:0044265 206 0.026
membrane organization GO:0061024 245 0.026
cytoplasmic transport GO:0016482 234 0.026
sulfur compound metabolic process GO:0006790 100 0.025
cofactor metabolic process GO:0051186 80 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
nucleoside metabolic process GO:0009116 246 0.025
positive regulation of programmed cell death GO:0043068 218 0.025
anion transport GO:0006820 177 0.025
striated muscle tissue development GO:0014706 293 0.025
carboxylic acid biosynthetic process GO:0046394 86 0.024
muscle tissue development GO:0060537 308 0.024
small molecule catabolic process GO:0044282 71 0.023
peptidyl amino acid modification GO:0018193 336 0.023
cellular homeostasis GO:0019725 240 0.023
alpha amino acid metabolic process GO:1901605 59 0.023
regulation of membrane potential GO:0042391 192 0.023
cation transmembrane transport GO:0098655 266 0.023
carbohydrate derivative catabolic process GO:1901136 231 0.023
glycosyl compound catabolic process GO:1901658 206 0.023
carboxylic acid catabolic process GO:0046395 51 0.023
protein catabolic process GO:0030163 221 0.023
organic anion transport GO:0015711 137 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
organic acid transport GO:0015849 101 0.022
positive regulation of protein modification process GO:0031401 299 0.022
organophosphate catabolic process GO:0046434 232 0.022
fatty acid metabolic process GO:0006631 121 0.022
purine containing compound catabolic process GO:0072523 213 0.022
cell type specific apoptotic process GO:0097285 268 0.022
intracellular protein transport GO:0006886 204 0.022
positive regulation of cell death GO:0010942 224 0.021
protein ubiquitination GO:0016567 171 0.021
small molecule biosynthetic process GO:0044283 132 0.021
ras protein signal transduction GO:0007265 77 0.021
nucleoside catabolic process GO:0009164 206 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
organic acid biosynthetic process GO:0016053 86 0.020
nucleotide catabolic process GO:0009166 217 0.020
response to organic cyclic compound GO:0014070 198 0.020
small gtpase mediated signal transduction GO:0007264 97 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
purine nucleoside catabolic process GO:0006152 205 0.019
protein localization to organelle GO:0033365 185 0.019
regulation of cell activation GO:0050865 289 0.019
multicellular organism growth GO:0035264 161 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
muscle cell differentiation GO:0042692 261 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
cellular chemical homeostasis GO:0055082 215 0.019
homeostasis of number of cells GO:0048872 210 0.019
negative regulation of molecular function GO:0044092 258 0.019
reactive oxygen species metabolic process GO:0072593 84 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
maintenance of location GO:0051235 89 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
camera type eye development GO:0043010 266 0.018
cellular ion homeostasis GO:0006873 165 0.018
forebrain development GO:0030900 302 0.018
negative regulation of protein metabolic process GO:0051248 282 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
divalent inorganic cation transport GO:0072511 178 0.017
regulation of neuron differentiation GO:0045664 281 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
carboxylic acid transport GO:0046942 100 0.017
regulation of homeostatic process GO:0032844 182 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
mapk cascade GO:0000165 281 0.017
rho protein signal transduction GO:0007266 32 0.017
immune effector process GO:0002252 321 0.016
regulation of cell cycle GO:0051726 281 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
cellular protein catabolic process GO:0044257 155 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
multicellular organismal signaling GO:0035637 91 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
renal system development GO:0072001 225 0.016
anion transmembrane transport GO:0098656 71 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
neuronal action potential GO:0019228 54 0.016
ubiquitin dependent protein catabolic process GO:0006511 129 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
gland development GO:0048732 330 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
cation homeostasis GO:0055080 212 0.016
regulation of hormone levels GO:0010817 211 0.016
regulation of cytokine production GO:0001817 266 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
regulation of secretion GO:0051046 274 0.016
positive regulation of cell development GO:0010720 237 0.016
regulation of kinase activity GO:0043549 249 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
metal ion homeostasis GO:0055065 189 0.015
organelle fission GO:0048285 170 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.015
sensory perception GO:0007600 245 0.015
transmission of nerve impulse GO:0019226 76 0.015
action potential GO:0001508 78 0.015
regulation of protein localization GO:0032880 231 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
cellular modified amino acid metabolic process GO:0006575 63 0.015
fat cell differentiation GO:0045444 160 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
skeletal system development GO:0001501 356 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
dna metabolic process GO:0006259 303 0.015
ossification GO:0001503 216 0.015
regulation of mapk cascade GO:0043408 248 0.015
regulation of hydrolase activity GO:0051336 246 0.015
response to nutrient levels GO:0031667 109 0.015
modification dependent protein catabolic process GO:0019941 133 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
sequestering of calcium ion GO:0051208 18 0.014
generation of precursor metabolites and energy GO:0006091 103 0.014
cytokine production GO:0001816 319 0.014
alpha amino acid catabolic process GO:1901606 18 0.014
muscle system process GO:0003012 141 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
regulation of protein kinase activity GO:0045859 232 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
endomembrane system organization GO:0010256 147 0.014
regulation of anatomical structure size GO:0090066 178 0.014
response to acid chemical GO:0001101 111 0.014
regulation of secretion by cell GO:1903530 249 0.014
urogenital system development GO:0001655 261 0.014
response to oxidative stress GO:0006979 123 0.014
t cell activation GO:0042110 289 0.014
regulation of transferase activity GO:0051338 263 0.014
negative regulation of protein modification process GO:0031400 163 0.014
microtubule based process GO:0007017 236 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
skeletal muscle organ development GO:0060538 163 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
cellular amino acid biosynthetic process GO:0008652 22 0.014
actin cytoskeleton organization GO:0030036 220 0.014
response to inorganic substance GO:0010035 96 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
cellular metal ion homeostasis GO:0006875 151 0.013
lateral inhibition GO:0046331 1 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
skin development GO:0043588 220 0.013
neuron death GO:0070997 154 0.013
leukocyte differentiation GO:0002521 342 0.013
cell adhesion GO:0007155 329 0.013
sensory organ morphogenesis GO:0090596 242 0.013
regulation of ion transport GO:0043269 215 0.013
innate immune response GO:0045087 157 0.013
germ cell development GO:0007281 185 0.013
protein localization to membrane GO:0072657 108 0.013
coenzyme biosynthetic process GO:0009108 23 0.013
spermatid differentiation GO:0048515 115 0.013
negative regulation of immune system process GO:0002683 209 0.013
calcium ion transport GO:0006816 159 0.013
regulation of nucleoside metabolic process GO:0009118 130 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
regulation of system process GO:0044057 200 0.013
myeloid cell differentiation GO:0030099 233 0.013
regulation of cellular response to stress GO:0080135 159 0.013
mitochondrion organization GO:0007005 134 0.013
sequestering of metal ion GO:0051238 19 0.013
locomotory behavior GO:0007626 195 0.013
chromatin modification GO:0016568 187 0.013
alcohol metabolic process GO:0006066 116 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
protein targeting GO:0006605 143 0.013
response to peptide GO:1901652 136 0.013
multicellular organismal homeostasis GO:0048871 164 0.012
monosaccharide metabolic process GO:0005996 106 0.012
nuclear transport GO:0051169 139 0.012
protein maturation GO:0051604 176 0.012
rna interference GO:0016246 2 0.012
alpha amino acid biosynthetic process GO:1901607 15 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
cellular response to peptide GO:1901653 92 0.012
nucleoside phosphate biosynthetic process GO:1901293 79 0.012
protein import GO:0017038 101 0.012
lymphocyte proliferation GO:0046651 164 0.012
circulatory system process GO:0003013 197 0.012
positive regulation of organelle organization GO:0010638 128 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
rhythmic process GO:0048511 174 0.012
blood circulation GO:0008015 195 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
regulation of cell projection organization GO:0031344 206 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
divalent metal ion transport GO:0070838 172 0.012
glutamate biosynthetic process GO:0006537 2 0.012
cellular response to peptide hormone stimulus GO:0071375 92 0.012
response to extracellular stimulus GO:0009991 127 0.012
myeloid cell homeostasis GO:0002262 114 0.012
telencephalon development GO:0021537 186 0.012
hormone secretion GO:0046879 128 0.012
aspartate family amino acid metabolic process GO:0009066 10 0.012
epithelial cell development GO:0002064 159 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
compound eye development GO:0048749 1 0.011
chromatin organization GO:0006325 206 0.011
mitotic cell cycle GO:0000278 195 0.011
response to radiation GO:0009314 165 0.011
glycerolipid metabolic process GO:0046486 122 0.011
hexose metabolic process GO:0019318 98 0.011
fat soluble vitamin biosynthetic process GO:0042362 4 0.011
positive regulation of cell activation GO:0050867 158 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
tissue homeostasis GO:0001894 115 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
neuron apoptotic process GO:0051402 142 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
connective tissue development GO:0061448 179 0.011
positive regulation of growth GO:0045927 104 0.011
lymphocyte differentiation GO:0030098 242 0.011
tube formation GO:0035148 140 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
cofactor biosynthetic process GO:0051188 41 0.011
inflammatory response GO:0006954 244 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
regulation of cell motility GO:2000145 236 0.011
regulation of proteolysis GO:0030162 164 0.011
response to endoplasmic reticulum stress GO:0034976 53 0.011
cellular alcohol biosynthetic process GO:0044108 3 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
protein localization to nucleus GO:0034504 121 0.011
regulation of defense response GO:0031347 233 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
glutamine family amino acid biosynthetic process GO:0009084 2 0.011
negative regulation of cell development GO:0010721 169 0.011
response to lipopolysaccharide GO:0032496 128 0.011
cellular alcohol metabolic process GO:0044107 3 0.011
axonogenesis GO:0007409 274 0.011
cellular response to lipid GO:0071396 145 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
wnt signaling pathway GO:0016055 188 0.011
cellular response to insulin stimulus GO:0032869 78 0.011
carbohydrate homeostasis GO:0033500 128 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
purine ribonucleotide biosynthetic process GO:0009152 59 0.011
protein processing GO:0016485 163 0.011
synaptic transmission GO:0007268 329 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
glycoprotein metabolic process GO:0009100 116 0.011
peptide transport GO:0015833 133 0.011
regulation of transmembrane transport GO:0034762 128 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
amide transport GO:0042886 138 0.011
lipid localization GO:0010876 126 0.011
regulation of protein catabolic process GO:0042176 108 0.011
mitotic cell cycle process GO:1903047 159 0.010
organelle localization GO:0051640 179 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
positive regulation of transferase activity GO:0051347 167 0.010
regulation of purine nucleotide catabolic process GO:0033121 122 0.010
response to insulin GO:0032868 100 0.010
purine containing compound biosynthetic process GO:0072522 70 0.010
anatomical structure homeostasis GO:0060249 145 0.010
lipid catabolic process GO:0016042 69 0.010
carbohydrate biosynthetic process GO:0016051 74 0.010
nuclear division GO:0000280 158 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
response to peptide hormone GO:0043434 127 0.010
gtp metabolic process GO:0046039 144 0.010
epithelial cell proliferation GO:0050673 174 0.010
calcium ion homeostasis GO:0055074 127 0.010
regulation of protein transport GO:0051223 163 0.010
positive regulation of nervous system development GO:0051962 221 0.010
cellular divalent inorganic cation homeostasis GO:0072503 127 0.010
monocarboxylic acid biosynthetic process GO:0072330 61 0.010
blood vessel morphogenesis GO:0048514 285 0.010
developmental maturation GO:0021700 193 0.010
regulation of intracellular transport GO:0032386 159 0.010
dephosphorylation GO:0016311 129 0.010
regulation of cell migration GO:0030334 219 0.010
proteasomal protein catabolic process GO:0010498 98 0.010
cellular component assembly involved in morphogenesis GO:0010927 139 0.010
asymmetric stem cell division GO:0098722 3 0.010
gtp catabolic process GO:0006184 143 0.010

Gpt2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.048
inherited metabolic disorder DOID:655 0 0.036
amino acid metabolic disorder DOID:9252 0 0.023
nervous system disease DOID:863 0 0.022
disease of anatomical entity DOID:7 0 0.022
musculoskeletal system disease DOID:17 0 0.014
central nervous system disease DOID:331 0 0.014
immune system disease DOID:2914 0 0.013
bone development disease DOID:0080006 0 0.012
connective tissue disease DOID:65 0 0.012
bone disease DOID:0080001 0 0.012
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
hematopoietic system disease DOID:74 0 0.010
cardiovascular system disease DOID:1287 0 0.010