Mus musculus

61 known processes

E2f6

E2F transcription factor 6

(Aliases: E2F6b,AI462434,EMA)

E2f6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin modification GO:0016568 187 0.095
dna metabolic process GO:0006259 303 0.079
Fly
chromatin organization GO:0006325 206 0.077
peptidyl amino acid modification GO:0018193 336 0.073
cellular amino acid metabolic process GO:0006520 103 0.067
histone modification GO:0016570 159 0.067
leukocyte differentiation GO:0002521 342 0.063
protein modification by small protein conjugation or removal GO:0070647 207 0.056
apoptotic signaling pathway GO:0097190 306 0.053
Mouse
covalent chromatin modification GO:0016569 163 0.052
amine metabolic process GO:0009308 45 0.050
cellular amine metabolic process GO:0044106 44 0.050
positive regulation of immature t cell proliferation GO:0033091 4 0.047
gene silencing GO:0016458 38 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.046
regionalization GO:0003002 337 0.044
t cell activation GO:0042110 289 0.043
male gamete generation GO:0048232 285 0.043
regulation of cell activation GO:0050865 289 0.043
transmembrane transport GO:0055085 412 0.043
negative regulation of protein metabolic process GO:0051248 282 0.042
spermatogenesis GO:0007283 284 0.042
oxidation reduction process GO:0055114 342 0.042
skeletal system development GO:0001501 356 0.042
lymphocyte differentiation GO:0030098 242 0.042
response to organic cyclic compound GO:0014070 198 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
macromolecule methylation GO:0043414 120 0.039
negative regulation of cellular protein metabolic process GO:0032269 247 0.039
cellular ketone metabolic process GO:0042180 84 0.039
regulation of apoptotic signaling pathway GO:2001233 197 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.039
organonitrogen compound biosynthetic process GO:1901566 192 0.039
methylation GO:0032259 134 0.037
response to oxidative stress GO:0006979 123 0.037
cellular response to lipid GO:0071396 145 0.035
regulation of lymphocyte activation GO:0051249 240 0.034
protein ubiquitination GO:0016567 171 0.034
positive regulation of cellular amine metabolic process GO:0033240 5 0.033
regulation of organelle organization GO:0033043 289 0.032
regulation of cellular ketone metabolic process GO:0010565 66 0.032
negative regulation of molecular function GO:0044092 258 0.031
leukocyte proliferation GO:0070661 172 0.031
protein methylation GO:0006479 81 0.031
nitrogen compound transport GO:0071705 271 0.030
negative regulation of protein modification process GO:0031400 163 0.030
cytokine production GO:0001816 319 0.029
mitotic cell cycle GO:0000278 195 0.029
cellular lipid metabolic process GO:0044255 323 0.029
negative regulation of immune system process GO:0002683 209 0.028
response to organonitrogen compound GO:0010243 246 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
positive regulation of protein modification process GO:0031401 299 0.027
histone h2a ubiquitination GO:0033522 3 0.027
membrane organization GO:0061024 245 0.026
ion transmembrane transport GO:0034220 361 0.026
positive regulation of cell death GO:0010942 224 0.026
Fly
regulation of transferase activity GO:0051338 263 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.025
wnt signaling pathway GO:0016055 188 0.025
ribonucleotide metabolic process GO:0009259 291 0.025
cation transport GO:0006812 399 0.025
b cell activation GO:0042113 161 0.025
regulation of t cell activation GO:0050863 170 0.025
positive regulation of cell activation GO:0050867 158 0.025
protein catabolic process GO:0030163 221 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
response to acid chemical GO:0001101 111 0.024
macromolecule catabolic process GO:0009057 281 0.024
lymphocyte proliferation GO:0046651 164 0.024
intracellular protein transport GO:0006886 204 0.024
negative regulation of apoptotic signaling pathway GO:2001234 104 0.024
regulation of cell cycle GO:0051726 281 0.024
Mouse Fly
regulation of membrane potential GO:0042391 192 0.024
ras protein signal transduction GO:0007265 77 0.023
carbohydrate metabolic process GO:0005975 230 0.023
cation transmembrane transport GO:0098655 266 0.023
neural tube development GO:0021915 160 0.023
embryonic organ morphogenesis GO:0048562 276 0.023
monocarboxylic acid metabolic process GO:0032787 191 0.023
peptidyl lysine modification GO:0018205 77 0.023
protein alkylation GO:0008213 81 0.023
small gtpase mediated signal transduction GO:0007264 97 0.023
anion transport GO:0006820 177 0.022
cellular response to acid chemical GO:0071229 68 0.022
muscle cell differentiation GO:0042692 261 0.022
histone methylation GO:0016571 71 0.022
cellular homeostasis GO:0019725 240 0.022
Mouse
regulation of cytokine production GO:0001817 266 0.022
mapk cascade GO:0000165 281 0.022
protein processing GO:0016485 163 0.021
striated muscle tissue development GO:0014706 293 0.021
cell type specific apoptotic process GO:0097285 268 0.021
Mouse Fly
muscle tissue development GO:0060537 308 0.021
Fly
intrinsic apoptotic signaling pathway GO:0097193 132 0.021
Mouse
t cell differentiation GO:0030217 174 0.021
camera type eye development GO:0043010 266 0.021
immune effector process GO:0002252 321 0.021
cytoplasmic transport GO:0016482 234 0.021
nucleotide metabolic process GO:0009117 332 0.020
protein maturation GO:0051604 176 0.020
response to inorganic substance GO:0010035 96 0.020
regulation of kinase activity GO:0043549 249 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
purine containing compound metabolic process GO:0072521 311 0.020
cellular response to dna damage stimulus GO:0006974 207 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
regulation of protein kinase activity GO:0045859 232 0.020
developmental maturation GO:0021700 193 0.019
locomotory behavior GO:0007626 195 0.019
regulation of mapk cascade GO:0043408 248 0.019
circulatory system process GO:0003013 197 0.019
Mouse
sensory perception GO:0007600 245 0.019
regulation of leukocyte differentiation GO:1902105 159 0.019
anatomical structure homeostasis GO:0060249 145 0.019
regulation of protein localization GO:0032880 231 0.019
regulation of secretion GO:0051046 274 0.019
regulation of proteolysis GO:0030162 164 0.019
dna alkylation GO:0006305 43 0.019
organic cyclic compound catabolic process GO:1901361 295 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
mitochondrion organization GO:0007005 134 0.018
regulation of hydrolase activity GO:0051336 246 0.018
regulation of ion transport GO:0043269 215 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
inorganic ion transmembrane transport GO:0098660 234 0.018
inflammatory response GO:0006954 244 0.018
regulation of defense response GO:0031347 233 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
nucleocytoplasmic transport GO:0006913 139 0.017
regulation of homeostatic process GO:0032844 182 0.017
homeostasis of number of cells GO:0048872 210 0.017
b cell proliferation GO:0042100 53 0.017
response to reactive oxygen species GO:0000302 56 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
protein localization to organelle GO:0033365 185 0.017
fat cell differentiation GO:0045444 160 0.017
cellular response to oxidative stress GO:0034599 76 0.017
response to sterol GO:0036314 4 0.017
multicellular organism growth GO:0035264 161 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
regulation of secretion by cell GO:1903530 249 0.017
nuclear transport GO:0051169 139 0.017
negative regulation of organelle organization GO:0010639 90 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
muscle system process GO:0003012 141 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
blood circulation GO:0008015 195 0.017
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.017
ossification GO:0001503 216 0.016
urogenital system development GO:0001655 261 0.016
divalent inorganic cation transport GO:0072511 178 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
carboxylic acid biosynthetic process GO:0046394 86 0.016
dna methylation GO:0006306 43 0.016
myeloid cell differentiation GO:0030099 233 0.016
regulation of t cell differentiation GO:0045580 83 0.016
microtubule based process GO:0007017 236 0.016
regulation of protein transport GO:0051223 163 0.016
response to lipopolysaccharide GO:0032496 128 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
cell maturation GO:0048469 127 0.016
striated muscle cell development GO:0055002 125 0.016
positive regulation of lymphocyte activation GO:0051251 140 0.016
protein targeting GO:0006605 143 0.016
cell cycle comprising mitosis without cytokinesis GO:0033301 1 0.016
gland development GO:0048732 330 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
regulation of response to wounding GO:1903034 189 0.015
action potential GO:0001508 78 0.015
muscle contraction GO:0006936 101 0.015
germ cell development GO:0007281 185 0.015
Fly
digestive system development GO:0055123 200 0.015
skeletal system morphogenesis GO:0048705 203 0.015
nucleoside metabolic process GO:0009116 246 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
Fly
inorganic cation transmembrane transport GO:0098662 207 0.015
cellular protein catabolic process GO:0044257 155 0.015
cellular chemical homeostasis GO:0055082 215 0.015
regulation of lymphocyte differentiation GO:0045619 107 0.015
regulation of inflammatory response GO:0050727 147 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
organic acid biosynthetic process GO:0016053 86 0.015
protein import GO:0017038 101 0.015
renal system development GO:0072001 225 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
regulation of leukocyte proliferation GO:0070663 121 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
cell division GO:0051301 120 0.015
heterocycle catabolic process GO:0046700 280 0.015
skeletal muscle organ development GO:0060538 163 0.015
cellular response to hormone stimulus GO:0032870 150 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
stem cell differentiation GO:0048863 268 0.014
response to ionizing radiation GO:0010212 42 0.014
aromatic compound catabolic process GO:0019439 286 0.014
blood vessel morphogenesis GO:0048514 285 0.014
lipid biosynthetic process GO:0008610 179 0.014
connective tissue development GO:0061448 179 0.014
compound eye development GO:0048749 1 0.014
lymphocyte mediated immunity GO:0002449 139 0.014
regulation of cell motility GO:2000145 236 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
regulation of t cell proliferation GO:0042129 92 0.014
chemotaxis GO:0006935 247 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
Fly
regulation of hormone levels GO:0010817 211 0.014
divalent metal ion transport GO:0070838 172 0.014
muscle cell development GO:0055001 133 0.014
forebrain development GO:0030900 302 0.014
Mouse
regulation of neuron differentiation GO:0045664 281 0.014
cellular protein complex assembly GO:0043623 116 0.014
regulation of peptidase activity GO:0052547 96 0.014
carboxylic acid transport GO:0046942 100 0.014
innate immune response GO:0045087 157 0.014
small molecule biosynthetic process GO:0044283 132 0.013
response to insulin GO:0032868 100 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
organic anion transport GO:0015711 137 0.013
dna modification GO:0006304 50 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
transmission of nerve impulse GO:0019226 76 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
cofactor metabolic process GO:0051186 80 0.013
t cell proliferation GO:0042098 120 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
positive regulation of organelle organization GO:0010638 128 0.013
maintenance of location GO:0051235 89 0.013
sensory organ morphogenesis GO:0090596 242 0.013
axonogenesis GO:0007409 274 0.013
regulation of transmembrane transport GO:0034762 128 0.013
central nervous system neuron differentiation GO:0021953 162 0.013
t cell differentiation in thymus GO:0033077 77 0.013
regulation of cell projection organization GO:0031344 206 0.013
regulation of cell migration GO:0030334 219 0.013
positive regulation of b cell activation GO:0050871 49 0.013
glucose homeostasis GO:0042593 128 0.013
digestive tract development GO:0048565 190 0.013
regulation of lymphocyte proliferation GO:0050670 117 0.013
regulation of cellular response to stress GO:0080135 159 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
sulfur compound metabolic process GO:0006790 100 0.013
respiratory system development GO:0060541 190 0.013
cell adhesion GO:0007155 329 0.013
purine containing compound catabolic process GO:0072523 213 0.013
multicellular organismal signaling GO:0035637 91 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
calcium ion transport GO:0006816 159 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
multi multicellular organism process GO:0044706 109 0.012
cell fate commitment GO:0045165 210 0.012
endomembrane system organization GO:0010256 147 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
positive regulation of cell development GO:0010720 237 0.012
Fly
neuronal action potential GO:0019228 54 0.012
ear development GO:0043583 200 0.012
neuron death GO:0070997 154 0.012
protein localization to nucleus GO:0034504 121 0.012
organelle fission GO:0048285 170 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
rhythmic process GO:0048511 174 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
embryonic epithelial tube formation GO:0001838 130 0.012
respiratory tube development GO:0030323 167 0.012
endocytosis GO:0006897 168 0.012
dephosphorylation GO:0016311 129 0.012
organophosphate catabolic process GO:0046434 232 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
sequestering of calcium ion GO:0051208 18 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
regulation of cell cycle process GO:0010564 160 0.012
glycoprotein metabolic process GO:0009100 116 0.012
anion transmembrane transport GO:0098656 71 0.012
dendrite development GO:0016358 115 0.012
Fly
negative regulation of transferase activity GO:0051348 85 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
negative regulation of kinase activity GO:0033673 81 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
myosin filament assembly GO:0031034 2 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
nuclear import GO:0051170 95 0.011
adult behavior GO:0030534 135 0.011
epithelial cell proliferation GO:0050673 174 0.011
cellular ion homeostasis GO:0006873 165 0.011
fertilization GO:0009566 127 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
response to radiation GO:0009314 165 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
meiotic cell cycle GO:0051321 122 0.011
actin cytoskeleton organization GO:0030036 220 0.011
metal ion homeostasis GO:0055065 189 0.011
neuron apoptotic process GO:0051402 142 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
mitotic cell cycle process GO:1903047 159 0.011
digestive tract morphogenesis GO:0048546 147 0.011
positive regulation of t cell activation GO:0050870 101 0.011
histone monoubiquitination GO:0010390 3 0.011
alpha amino acid metabolic process GO:1901605 59 0.011
cell activation involved in immune response GO:0002263 126 0.011
regulation of anatomical structure size GO:0090066 178 0.011
Mouse
protein import into nucleus GO:0006606 95 0.011
epithelial cell development GO:0002064 159 0.011
Mouse
gastrulation GO:0007369 116 0.011
peptide transport GO:0015833 133 0.011
leukocyte mediated immunity GO:0002443 174 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
coenzyme metabolic process GO:0006732 52 0.011
cation homeostasis GO:0055080 212 0.011
positive regulation of proteolysis GO:0045862 85 0.011
protein localization to membrane GO:0072657 108 0.011
dna repair GO:0006281 107 0.011
calcium ion homeostasis GO:0055074 127 0.011
positive regulation of t cell proliferation GO:0042102 52 0.011
organelle localization GO:0051640 179 0.011
regulation of body fluid levels GO:0050878 162 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
tube formation GO:0035148 140 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
internal protein amino acid acetylation GO:0006475 42 0.010
development of primary sexual characteristics GO:0045137 143 0.010
rho protein signal transduction GO:0007266 32 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.010
proteasomal protein catabolic process GO:0010498 98 0.010
purine nucleoside triphosphate metabolic process GO:0009144 226 0.010
lateral inhibition GO:0046331 1 0.010
trunk segmentation GO:0035290 4 0.010
oocyte construction GO:0007308 2 0.010
positive regulation of growth GO:0045927 104 0.010
cellular response to molecule of bacterial origin GO:0071219 83 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
angiogenesis GO:0001525 201 0.010
tissue homeostasis GO:0001894 115 0.010
regulation of organ morphogenesis GO:2000027 144 0.010
regulation of intracellular transport GO:0032386 159 0.010
gonad development GO:0008406 141 0.010
positive regulation of t cell differentiation GO:0045582 52 0.010
regulation of protein maturation GO:1903317 96 0.010
myotube differentiation GO:0014902 105 0.010
regulation of chromosome organization GO:0033044 83 0.010
oocyte axis specification GO:0007309 2 0.010
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.010
regulation of cellular component biogenesis GO:0044087 181 0.010
regulation of multi organism process GO:0043900 111 0.010
Fly
histone lysine methylation GO:0034968 50 0.010
positive regulation of transferase activity GO:0051347 167 0.010
stem cell development GO:0048864 219 0.010
lung development GO:0030324 164 0.010
extrinsic apoptotic signaling pathway GO:0097191 126 0.010
positive regulation of cytokine production GO:0001819 174 0.010
positive regulation of lymphocyte proliferation GO:0050671 70 0.010
negative regulation of cell activation GO:0050866 111 0.010
developmental growth involved in morphogenesis GO:0060560 138 0.010
response to extracellular stimulus GO:0009991 127 0.010

E2f6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
nervous system disease DOID:863 0 0.047
sensory system disease DOID:0050155 0 0.022
eye and adnexa disease DOID:1492 0 0.022
central nervous system disease DOID:331 0 0.022
eye disease DOID:5614 0 0.019
neurodegenerative disease DOID:1289 0 0.018
musculoskeletal system disease DOID:17 0 0.013
disease of metabolism DOID:0014667 0 0.012
immune system disease DOID:2914 0 0.011
inherited metabolic disorder DOID:655 0 0.011
disease of cellular proliferation DOID:14566 0 0.010