Mus musculus

59 known processes

E2f5

E2F transcription factor 5

(Aliases: E2F-5,AU024671)

E2f5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of multi organism process GO:0043900 111 0.235
cellular response to dna damage stimulus GO:0006974 207 0.224
intrinsic apoptotic signaling pathway GO:0097193 132 0.219
Mouse
dna metabolic process GO:0006259 303 0.209
Fly
regulation of reproductive process GO:2000241 66 0.128
regulation of cell cycle GO:0051726 281 0.124
Mouse Fly
camera type eye development GO:0043010 266 0.120
apoptotic signaling pathway GO:0097190 306 0.110
Mouse
positive regulation of cell death GO:0010942 224 0.103
cell type specific apoptotic process GO:0097285 268 0.095
Mouse
positive regulation of cell development GO:0010720 237 0.093
regulation of cellular amino acid metabolic process GO:0006521 5 0.086
macromolecule methylation GO:0043414 120 0.081
germ cell development GO:0007281 185 0.079
Fly
positive regulation of apoptotic process GO:0043065 217 0.075
forebrain development GO:0030900 302 0.073
Mouse
amine metabolic process GO:0009308 45 0.067
oogenesis GO:0048477 56 0.065
Fly
embryonic epithelial tube formation GO:0001838 130 0.061
cellular amine metabolic process GO:0044106 44 0.059
maintenance of chromatin silencing GO:0006344 2 0.058
tube formation GO:0035148 140 0.055
epidermis development GO:0008544 187 0.052
transmembrane transport GO:0055085 412 0.051
embryonic organ morphogenesis GO:0048562 276 0.050
Worm
oocyte construction GO:0007308 2 0.049
Fly
positive regulation of reproductive process GO:2000243 19 0.048
epithelial tube formation GO:0072175 130 0.047
cilium morphogenesis GO:0060271 102 0.045
Mouse
sensory organ morphogenesis GO:0090596 242 0.044
epithelial tube morphogenesis GO:0060562 303 0.044
homeostasis of number of cells GO:0048872 210 0.043
neural tube development GO:0021915 160 0.042
negative regulation of growth GO:0045926 99 0.042
regulation of cellular ketone metabolic process GO:0010565 66 0.041
organic cyclic compound catabolic process GO:1901361 295 0.041
neural tube formation GO:0001841 108 0.041
cellular amino acid metabolic process GO:0006520 103 0.041
cell substrate adhesion GO:0031589 130 0.040
axonogenesis GO:0007409 274 0.039
positive regulation of programmed cell death GO:0043068 218 0.039
epithelial cell development GO:0002064 159 0.037
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.037
regulation of mitotic cell cycle GO:0007346 126 0.037
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
striated muscle tissue development GO:0014706 293 0.036
skeletal system development GO:0001501 356 0.035
cellular ketone metabolic process GO:0042180 84 0.035
cellular chemical homeostasis GO:0055082 215 0.035
skin development GO:0043588 220 0.035
posttranscriptional regulation of gene expression GO:0010608 155 0.035
muscle tissue development GO:0060537 308 0.035
cellular nitrogen compound catabolic process GO:0044270 280 0.034
dna modification GO:0006304 50 0.034
hematopoietic progenitor cell differentiation GO:0002244 143 0.033
organonitrogen compound biosynthetic process GO:1901566 192 0.033
dna alkylation GO:0006305 43 0.033
cellular homeostasis GO:0019725 240 0.031
Mouse
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.031
tube closure GO:0060606 91 0.031
macromolecule catabolic process GO:0009057 281 0.031
muscle cell differentiation GO:0042692 261 0.030
negative regulation of cell proliferation GO:0008285 296 0.030
histone modification GO:0016570 159 0.029
placenta development GO:0001890 140 0.029
primary neural tube formation GO:0014020 95 0.029
aromatic compound catabolic process GO:0019439 286 0.029
regulation of cytokine production GO:0001817 266 0.029
cellular lipid metabolic process GO:0044255 323 0.029
establishment of organelle localization GO:0051656 122 0.028
mitotic cell cycle GO:0000278 195 0.028
Mouse Fly
developmental programmed cell death GO:0010623 41 0.028
regulation of hydrolase activity GO:0051336 246 0.028
chemotaxis GO:0006935 247 0.028
retina development in camera type eye GO:0060041 119 0.027
rna processing GO:0006396 105 0.027
ubiquitin dependent protein catabolic process GO:0006511 129 0.027
cation transmembrane transport GO:0098655 266 0.027
sensory perception GO:0007600 245 0.026
embryonic appendage morphogenesis GO:0035113 126 0.025
endocytosis GO:0006897 168 0.025
negative regulation of cell cycle GO:0045786 123 0.025
Fly
toxin transport GO:1901998 38 0.024
regulation of cell activation GO:0050865 289 0.024
cytokine production GO:0001816 319 0.024
methylation GO:0032259 134 0.024
locomotory behavior GO:0007626 195 0.024
ion transmembrane transport GO:0034220 361 0.024
cellular response to external stimulus GO:0071496 88 0.024
regulation of body fluid levels GO:0050878 162 0.023
nucleoside phosphate metabolic process GO:0006753 338 0.023
nucleoside triphosphate metabolic process GO:0009141 230 0.023
eye photoreceptor cell development GO:0042462 31 0.023
cellular response to lipid GO:0071396 145 0.023
gland development GO:0048732 330 0.023
nucleoside monophosphate metabolic process GO:0009123 85 0.023
cellular protein catabolic process GO:0044257 155 0.023
multicellular organismal homeostasis GO:0048871 164 0.023
regulation of cell adhesion GO:0030155 154 0.022
negative regulation of cell development GO:0010721 169 0.022
myeloid cell homeostasis GO:0002262 114 0.022
epithelial cell proliferation GO:0050673 174 0.022
cation transport GO:0006812 399 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
regulation of purine nucleotide metabolic process GO:1900542 169 0.022
regulation of wnt signaling pathway GO:0030111 123 0.022
regulation of protein kinase activity GO:0045859 232 0.022
cell fate commitment GO:0045165 210 0.021
oocyte axis specification GO:0007309 2 0.021
Fly
positive regulation of glial cell proliferation GO:0060252 4 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.021
peptidyl amino acid modification GO:0018193 336 0.021
cellular component assembly involved in morphogenesis GO:0010927 139 0.020
Mouse
visual perception GO:0007601 52 0.020
dna recombination GO:0006310 92 0.020
ribonucleoside monophosphate metabolic process GO:0009161 80 0.020
ossification GO:0001503 216 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
neural precursor cell proliferation GO:0061351 121 0.019
mrna processing GO:0006397 63 0.019
digestive system development GO:0055123 200 0.019
Worm
organelle assembly GO:0070925 177 0.019
Mouse
extracellular structure organization GO:0043062 148 0.019
negative regulation of nervous system development GO:0051961 156 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
Worm
b cell activation GO:0042113 161 0.019
regulation of epithelial cell proliferation GO:0050678 141 0.019
regulation of cellular amine metabolic process GO:0033238 20 0.018
nuclear division GO:0000280 158 0.018
carbohydrate metabolic process GO:0005975 230 0.018
organism emergence from protective structure GO:0071684 4 0.018
placenta blood vessel development GO:0060674 31 0.018
nucleoside metabolic process GO:0009116 246 0.018
hindbrain development GO:0030902 128 0.018
positive regulation of multi organism process GO:0043902 26 0.018
protein maturation GO:0051604 176 0.018
cell division GO:0051301 120 0.018
wnt signaling pathway GO:0016055 188 0.018
developmental maturation GO:0021700 193 0.018
Fly
regulation of neuron differentiation GO:0045664 281 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
positive regulation of wnt signaling pathway GO:0030177 45 0.018
microtubule based process GO:0007017 236 0.018
cell adhesion GO:0007155 329 0.018
female gamete generation GO:0007292 74 0.018
Fly
myeloid cell differentiation GO:0030099 233 0.017
meiotic cell cycle GO:0051321 122 0.017
male gamete generation GO:0048232 285 0.017
cardiac chamber development GO:0003205 108 0.017
maintenance of location GO:0051235 89 0.017
blood circulation GO:0008015 195 0.017
Mouse
regulation of t cell activation GO:0050863 170 0.017
neural tube closure GO:0001843 90 0.017
regulation of protein localization GO:0032880 231 0.017
fat cell differentiation GO:0045444 160 0.017
ras protein signal transduction GO:0007265 77 0.017
Worm
mitotic cell cycle process GO:1903047 159 0.017
Mouse Fly
neural retina development GO:0003407 41 0.016
cell growth GO:0016049 130 0.016
multi multicellular organism process GO:0044706 109 0.016
cilium assembly GO:0042384 81 0.016
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.016
protein catabolic process GO:0030163 221 0.016
oxidation reduction process GO:0055114 342 0.016
negative regulation of molecular function GO:0044092 258 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
tissue homeostasis GO:0001894 115 0.016
wound healing GO:0042060 157 0.016
response to radiation GO:0009314 165 0.016
atp dependent chromatin remodeling GO:0043044 9 0.016
chromatin remodeling at centromere GO:0031055 2 0.016
cation homeostasis GO:0055080 212 0.016
synaptic transmission GO:0007268 329 0.015
retina morphogenesis in camera type eye GO:0060042 45 0.015
negative regulation of cell cycle phase transition GO:1901988 48 0.015
Fly
negative regulation of protein modification process GO:0031400 163 0.015
positive regulation of defense response GO:0031349 124 0.015
eye photoreceptor cell differentiation GO:0001754 41 0.015
protein processing GO:0016485 163 0.015
regulation of secretion by cell GO:1903530 249 0.015
divalent inorganic cation transport GO:0072511 178 0.015
embryonic limb morphogenesis GO:0030326 126 0.015
organelle localization GO:0051640 179 0.015
transmission of nerve impulse GO:0019226 76 0.015
cell maturation GO:0048469 127 0.015
Fly
metal ion homeostasis GO:0055065 189 0.015
regulation of antimicrobial humoral response GO:0002759 3 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
dna methylation GO:0006306 43 0.014
regulation of kinase activity GO:0043549 249 0.014
gliogenesis GO:0042063 141 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
regulation of cell projection organization GO:0031344 206 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
i kappab kinase nf kappab signaling GO:0007249 85 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
compound eye development GO:0048749 1 0.014
negative regulation of transferase activity GO:0051348 85 0.014
regulation of cell cycle process GO:0010564 160 0.014
Fly
regulation of cell motility GO:2000145 236 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
cognition GO:0050890 149 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
positive regulation of nervous system development GO:0051962 221 0.013
spermatogenesis GO:0007283 284 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
regulation of membrane potential GO:0042391 192 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
embryonic camera type eye development GO:0031076 36 0.013
glial cell differentiation GO:0010001 131 0.013
negative regulation of cell activation GO:0050866 111 0.013
cellular response to extracellular stimulus GO:0031668 81 0.013
positive regulation of macroautophagy GO:0016239 3 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
extracellular matrix organization GO:0030198 147 0.013
nucleobase containing small molecule metabolic process GO:0055086 352 0.013
antimicrobial peptide biosynthetic process GO:0002777 2 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
purine containing compound metabolic process GO:0072521 311 0.013
cardiocyte differentiation GO:0035051 87 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
antibacterial peptide biosynthetic process GO:0002780 2 0.013
nucleosome disassembly GO:0006337 1 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
alcohol metabolic process GO:0006066 116 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
response to extracellular stimulus GO:0009991 127 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
positive regulation of dna templated transcription elongation GO:0032786 2 0.012
regulation of cellular component size GO:0032535 121 0.012
Mouse
positive regulation of t cell activation GO:0050870 101 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
regulation of lymphocyte differentiation GO:0045619 107 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
small molecule catabolic process GO:0044282 71 0.012
negative regulation of dna replication GO:0008156 4 0.012
Fly
t cell activation GO:0042110 289 0.012
positive regulation of cell activation GO:0050867 158 0.012
cardiac chamber morphogenesis GO:0003206 93 0.012
development of primary male sexual characteristics GO:0046546 88 0.012
regulation of transferase activity GO:0051338 263 0.012
cytoplasmic transport GO:0016482 234 0.012
response to organonitrogen compound GO:0010243 246 0.012
carboxylic acid transport GO:0046942 100 0.012
protein secretion GO:0009306 111 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
sodium ion transport GO:0006814 73 0.012
fertilization GO:0009566 127 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
innate immune response GO:0045087 157 0.012
gonad development GO:0008406 141 0.012
regulation of mitotic cell cycle phase transition GO:1901990 73 0.012
Fly
response to acid chemical GO:0001101 111 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
covalent chromatin modification GO:0016569 163 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
regulation of defense response to bacterium GO:1900424 3 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.012
urogenital system development GO:0001655 261 0.012
positive regulation of cellular component biogenesis GO:0044089 94 0.011
response to lipopolysaccharide GO:0032496 128 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
leukocyte differentiation GO:0002521 342 0.011
cardiac muscle tissue development GO:0048738 130 0.011
organophosphate catabolic process GO:0046434 232 0.011
positive regulation of cell projection organization GO:0031346 95 0.011
antibacterial peptide production GO:0002778 2 0.011
negative regulation of lymphocyte activation GO:0051250 91 0.011
regulation of cell migration GO:0030334 219 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
organelle fission GO:0048285 170 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
regulation of protein catabolic process GO:0042176 108 0.011
dna conformation change GO:0071103 37 0.011
regulation of neuron projection development GO:0010975 169 0.011
mitotic chromosome condensation GO:0007076 1 0.011
digestive tract morphogenesis GO:0048546 147 0.011
Worm
respiratory system development GO:0060541 190 0.011
leukocyte migration GO:0050900 124 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
response to oxidative stress GO:0006979 123 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
heart trabecula morphogenesis GO:0061384 26 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
purine nucleotide metabolic process GO:0006163 302 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
response to organic cyclic compound GO:0014070 198 0.011
mitochondrion organization GO:0007005 134 0.011
cellular response to nutrient levels GO:0031669 64 0.011
lymphocyte proliferation GO:0046651 164 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
viral transcription GO:0019083 3 0.011
cellular protein complex assembly GO:0043623 116 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
ribonucleoprotein complex subunit organization GO:0071826 28 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
Worm
rhythmic process GO:0048511 174 0.010
cellular metal ion homeostasis GO:0006875 151 0.010
renal system development GO:0072001 225 0.010
purine ribonucleotide metabolic process GO:0009150 290 0.010
limb morphogenesis GO:0035108 149 0.010
leukocyte proliferation GO:0070661 172 0.010
modification dependent protein catabolic process GO:0019941 133 0.010
regulation of cell growth GO:0001558 91 0.010
kidney development GO:0001822 213 0.010
ribonucleoside catabolic process GO:0042454 206 0.010
regulation of anatomical structure size GO:0090066 178 0.010
Mouse
regulation of neural precursor cell proliferation GO:2000177 70 0.010
macromolecule deacylation GO:0098732 37 0.010
chromatin modification GO:0016568 187 0.010

E2f5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
central nervous system disease DOID:331 0 0.010