Mus musculus

124 known processes

E2f4

E2F transcription factor 4

(Aliases: 2010111M04Rik,AI427446)

E2f4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.172
Fly
cellular response to dna damage stimulus GO:0006974 207 0.164
nucleosome disassembly GO:0006337 1 0.142
muscle cell differentiation GO:0042692 261 0.114
carbohydrate metabolic process GO:0005975 230 0.100
cellular amino acid metabolic process GO:0006520 103 0.089
ras protein signal transduction GO:0007265 77 0.086
Worm
regulation of cell cycle GO:0051726 281 0.084
Mouse Fly
small gtpase mediated signal transduction GO:0007264 97 0.082
Worm
chromatin disassembly GO:0031498 1 0.080
male gamete generation GO:0048232 285 0.074
muscle tissue development GO:0060537 308 0.074
cellular ketone metabolic process GO:0042180 84 0.069
regulation of cellular amino acid metabolic process GO:0006521 5 0.069
amine metabolic process GO:0009308 45 0.068
striated muscle tissue development GO:0014706 293 0.065
regulation of cellular ketone metabolic process GO:0010565 66 0.063
cellular component assembly involved in morphogenesis GO:0010927 139 0.063
mitotic cell cycle GO:0000278 195 0.060
carbohydrate derivative biosynthetic process GO:1901137 183 0.060
regulation of cellular catabolic process GO:0031329 242 0.059
actin cytoskeleton organization GO:0030036 220 0.059
cell fate commitment GO:0045165 210 0.057
apoptotic signaling pathway GO:0097190 306 0.056
Mouse
peptidyl amino acid modification GO:0018193 336 0.056
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.056
cellular amine metabolic process GO:0044106 44 0.052
myeloid cell differentiation GO:0030099 233 0.051
negative regulation of cellular protein metabolic process GO:0032269 247 0.050
regulation of cell cycle process GO:0010564 160 0.048
Fly
positive regulation of apoptotic process GO:0043065 217 0.046
positive regulation of cellular amine metabolic process GO:0033240 5 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.045
homeostasis of number of cells GO:0048872 210 0.044
cell type specific apoptotic process GO:0097285 268 0.044
Mouse
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 3 0.043
spermatogenesis GO:0007283 284 0.041
mitotic cell cycle process GO:1903047 159 0.040
regulation of hydrolase activity GO:0051336 246 0.040
glycoprotein biosynthetic process GO:0009101 89 0.040
macromolecule catabolic process GO:0009057 281 0.039
embryonic organ morphogenesis GO:0048562 276 0.038
Worm
cellular response to organonitrogen compound GO:0071417 145 0.038
cilium morphogenesis GO:0060271 102 0.038
regulation of apoptotic signaling pathway GO:2001233 197 0.037
heterocycle catabolic process GO:0046700 280 0.036
leukocyte differentiation GO:0002521 342 0.036
positive regulation of cell development GO:0010720 237 0.035
positive regulation of protein phosphorylation GO:0001934 242 0.034
axonogenesis GO:0007409 274 0.034
nucleoside phosphate metabolic process GO:0006753 338 0.033
cation transport GO:0006812 399 0.033
protein dna complex disassembly GO:0032986 1 0.032
intrinsic apoptotic signaling pathway GO:0097193 132 0.032
Mouse
nitrogen compound transport GO:0071705 271 0.032
organonitrogen compound biosynthetic process GO:1901566 192 0.031
lipid biosynthetic process GO:0008610 179 0.031
nucleobase containing small molecule metabolic process GO:0055086 352 0.031
meiotic cell cycle GO:0051321 122 0.031
camera type eye development GO:0043010 266 0.031
regulation of proteolysis GO:0030162 164 0.030
positive regulation of programmed cell death GO:0043068 218 0.030
purine nucleoside metabolic process GO:0042278 241 0.030
gland development GO:0048732 330 0.030
double strand break repair GO:0006302 48 0.029
cellular carbohydrate metabolic process GO:0044262 119 0.029
t cell activation GO:0042110 289 0.028
regulation of cellular amine metabolic process GO:0033238 20 0.028
oxidation reduction process GO:0055114 342 0.028
dna repair GO:0006281 107 0.028
regulation of protein localization GO:0032880 231 0.028
protein maturation GO:0051604 176 0.028
immune effector process GO:0002252 321 0.027
cellular lipid metabolic process GO:0044255 323 0.027
response to organonitrogen compound GO:0010243 246 0.027
anoikis GO:0043276 6 0.027
Mouse
endocytosis GO:0006897 168 0.027
regulation of secretion by cell GO:1903530 249 0.026
cilium assembly GO:0042384 81 0.026
circulatory system process GO:0003013 197 0.026
regulation of transferase activity GO:0051338 263 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
positive regulation of cell death GO:0010942 224 0.026
maintenance of chromatin silencing GO:0006344 2 0.026
protein modification by small protein conjugation or removal GO:0070647 207 0.026
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.025
ribonucleoside triphosphate catabolic process GO:0009203 199 0.025
response to peptide hormone GO:0043434 127 0.025
regulation of cysteine type endopeptidase activity GO:2000116 65 0.025
epithelial cell development GO:0002064 159 0.025
negative regulation of cellular amine metabolic process GO:0033239 1 0.025
stem cell development GO:0048864 219 0.025
negative regulation of protein metabolic process GO:0051248 282 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
forebrain development GO:0030900 302 0.024
Mouse
cellular homeostasis GO:0019725 240 0.024
lymphocyte differentiation GO:0030098 242 0.024
protein processing GO:0016485 163 0.024
guanosine containing compound metabolic process GO:1901068 144 0.024
cell growth GO:0016049 130 0.024
carbohydrate biosynthetic process GO:0016051 74 0.024
dna replication GO:0006260 52 0.024
Fly
rho protein signal transduction GO:0007266 32 0.024
cellular macromolecule catabolic process GO:0044265 206 0.023
membrane organization GO:0061024 245 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
organonitrogen compound catabolic process GO:1901565 264 0.023
gene silencing GO:0016458 38 0.023
dna alkylation GO:0006305 43 0.023
regulation of ion transport GO:0043269 215 0.023
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.023
extrinsic apoptotic signaling pathway GO:0097191 126 0.023
divalent metal ion transport GO:0070838 172 0.023
purine containing compound metabolic process GO:0072521 311 0.023
establishment of organelle localization GO:0051656 122 0.022
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.022
organelle localization GO:0051640 179 0.022
cytoplasmic transport GO:0016482 234 0.022
covalent chromatin modification GO:0016569 163 0.022
blood vessel morphogenesis GO:0048514 285 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.021
Worm
nucleoside metabolic process GO:0009116 246 0.021
divalent inorganic cation transport GO:0072511 178 0.021
nuclear division GO:0000280 158 0.021
proteasomal protein catabolic process GO:0010498 98 0.021
negative regulation of apoptotic signaling pathway GO:2001234 104 0.021
cytokine production GO:0001816 319 0.021
gtp metabolic process GO:0046039 144 0.021
striated muscle myosin thick filament assembly GO:0071688 1 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
positive regulation of reproductive process GO:2000243 19 0.021
regulation of carbohydrate biosynthetic process GO:0043255 40 0.021
nucleoside catabolic process GO:0009164 206 0.021
calcium ion transport GO:0006816 159 0.021
positive regulation of protein modification process GO:0031401 299 0.021
cellular protein catabolic process GO:0044257 155 0.021
cellular ion homeostasis GO:0006873 165 0.020
aromatic compound catabolic process GO:0019439 286 0.020
asymmetric stem cell division GO:0098722 3 0.020
gliogenesis GO:0042063 141 0.020
phagocytosis GO:0006909 66 0.020
rna processing GO:0006396 105 0.020
modification dependent protein catabolic process GO:0019941 133 0.020
regulation of mapk cascade GO:0043408 248 0.020
negative regulation of protein modification process GO:0031400 163 0.020
gonad development GO:0008406 141 0.020
regulation of ras protein signal transduction GO:0046578 114 0.020
Worm
response to peptide GO:1901652 136 0.020
negative regulation of cell cycle GO:0045786 123 0.020
Fly
cation homeostasis GO:0055080 212 0.020
sensory perception GO:0007600 245 0.020
organophosphate catabolic process GO:0046434 232 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
glial cell differentiation GO:0010001 131 0.019
development of primary sexual characteristics GO:0045137 143 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
neural precursor cell proliferation GO:0061351 121 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
regulation of kinase activity GO:0043549 249 0.019
response to radiation GO:0009314 165 0.019
synaptic transmission GO:0007268 329 0.019
stem cell differentiation GO:0048863 268 0.019
response to acid chemical GO:0001101 111 0.019
g1 s transition of mitotic cell cycle GO:0000082 57 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
notch signaling pathway GO:0007219 71 0.019
spermatid differentiation GO:0048515 115 0.019
multicellular organismal signaling GO:0035637 91 0.018
dna modification GO:0006304 50 0.018
toxin transport GO:1901998 38 0.018
maintenance of location GO:0051235 89 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
regulation of secretion GO:0051046 274 0.018
regulation of cell cycle g1 s phase transition GO:1902806 35 0.018
Fly
transmembrane transport GO:0055085 412 0.018
transmission of nerve impulse GO:0019226 76 0.018
regulation of purine nucleotide catabolic process GO:0033121 122 0.018
cell adhesion GO:0007155 329 0.018
nucleotide catabolic process GO:0009166 217 0.018
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.018
Fly
purine nucleotide metabolic process GO:0006163 302 0.018
nucleotide metabolic process GO:0009117 332 0.018
ubiquitin dependent protein catabolic process GO:0006511 129 0.018
regulation of membrane potential GO:0042391 192 0.018
erythrocyte differentiation GO:0030218 88 0.018
regulation of protein processing GO:0070613 96 0.018
cellular chemical homeostasis GO:0055082 215 0.018
cardiac muscle tissue development GO:0048738 130 0.018
small molecule catabolic process GO:0044282 71 0.018
cardiocyte differentiation GO:0035051 87 0.018
regulation of mitotic cell cycle GO:0007346 126 0.018
Fly
dna endoreduplication GO:0042023 4 0.018
Fly
small molecule biosynthetic process GO:0044283 132 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.017
regulation of organelle organization GO:0033043 289 0.017
negative regulation of dna replication GO:0008156 4 0.017
Fly
regulation of cytoskeleton organization GO:0051493 122 0.017
b cell activation GO:0042113 161 0.017
spermatid development GO:0007286 108 0.017
regulation of protein kinase activity GO:0045859 232 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
sequestering of calcium ion GO:0051208 18 0.017
cellular response to peptide hormone stimulus GO:0071375 92 0.017
mapk cascade GO:0000165 281 0.017
carboxylic acid biosynthetic process GO:0046394 86 0.017
inflammatory response GO:0006954 244 0.017
compound eye development GO:0048749 1 0.017
regulation of multi organism process GO:0043900 111 0.017
lateral inhibition GO:0046331 1 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
oligosaccharide catabolic process GO:0009313 2 0.017
regulation of cytokine production GO:0001817 266 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
regionalization GO:0003002 337 0.016
Fly
blood circulation GO:0008015 195 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
striated muscle cell development GO:0055002 125 0.016
negative regulation of cell cycle phase transition GO:1901988 48 0.016
Fly
nucleoside phosphate catabolic process GO:1901292 222 0.016
skeletal muscle organ development GO:0060538 163 0.016
regulation of chromatin silencing GO:0031935 2 0.016
neural tube development GO:0021915 160 0.016
digestive system development GO:0055123 200 0.016
Worm
myosin filament assembly GO:0031034 2 0.016
regulation of hormone levels GO:0010817 211 0.016
regulation of peptidase activity GO:0052547 96 0.016
t cell differentiation GO:0030217 174 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
protein catabolic process GO:0030163 221 0.016
connective tissue development GO:0061448 179 0.016
regulation of transmembrane transport GO:0034762 128 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
myeloid cell homeostasis GO:0002262 114 0.016
organelle assembly GO:0070925 177 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.016
endomembrane system organization GO:0010256 147 0.015
neuron apoptotic process GO:0051402 142 0.015
dna damage response signal transduction resulting in transcription GO:0042772 2 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
neuron death GO:0070997 154 0.015
guanosine containing compound catabolic process GO:1901069 144 0.015
protein localization to organelle GO:0033365 185 0.015
cell substrate adhesion GO:0031589 130 0.015
germ cell development GO:0007281 185 0.015
Fly
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
cell junction maintenance GO:0034331 4 0.015
negative regulation of protein processing GO:0010955 79 0.015
chromatin modification GO:0016568 187 0.015
regulation of proteasomal protein catabolic process GO:0061136 46 0.015
cognition GO:0050890 149 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
regulation of cytoplasmic transport GO:1903649 112 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.015
protein complex disassembly GO:0043241 40 0.015
peptidyl tyrosine phosphorylation GO:0018108 143 0.015
meiotic nuclear division GO:0007126 115 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
positive regulation of cell activation GO:0050867 158 0.015
histone modification GO:0016570 159 0.015
organelle fission GO:0048285 170 0.014
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
sequestering of metal ion GO:0051238 19 0.014
organic anion transport GO:0015711 137 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
microtubule based process GO:0007017 236 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
response to nutrient levels GO:0031667 109 0.014
triglyceride biosynthetic process GO:0019432 17 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
muscle cell development GO:0055001 133 0.014
cellular calcium ion homeostasis GO:0006874 119 0.014
cardiac muscle cell differentiation GO:0055007 69 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
digestive tract morphogenesis GO:0048546 147 0.014
Worm
engulfment of apoptotic cell GO:0043652 3 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
protein secretion GO:0009306 111 0.014
negative regulation of ras protein signal transduction GO:0046580 18 0.014
Worm
positive regulation of nervous system development GO:0051962 221 0.014
epithelial tube morphogenesis GO:0060562 303 0.014
purine containing compound catabolic process GO:0072523 213 0.014
epithelial cell proliferation GO:0050673 174 0.014
response to oxidative stress GO:0006979 123 0.014
rna interference GO:0016246 2 0.014
cell cycle g1 s phase transition GO:0044843 57 0.014
glucose metabolic process GO:0006006 92 0.014
regulation of mrna metabolic process GO:1903311 43 0.014
leukocyte proliferation GO:0070661 172 0.014
negative regulation of neuron apoptotic process GO:0043524 92 0.014
plasma membrane organization GO:0007009 90 0.014
intracellular protein transport GO:0006886 204 0.014
negative regulation of chromatin silencing GO:0031936 1 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.014
nuclear transport GO:0051169 139 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
peptidyl tyrosine modification GO:0018212 145 0.014
regulation of cell migration GO:0030334 219 0.014
regulation of cell adhesion GO:0030155 154 0.014
cellular response to insulin stimulus GO:0032869 78 0.014
regulation of endopeptidase activity GO:0052548 89 0.013
regulation of cell activation GO:0050865 289 0.013
regulation of cellular response to stress GO:0080135 159 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
macromolecular complex disassembly GO:0032984 43 0.013
lymphocyte proliferation GO:0046651 164 0.013
glycosylation GO:0070085 62 0.013
peptide transport GO:0015833 133 0.013
lymphocyte activation involved in immune response GO:0002285 93 0.013
rna splicing GO:0008380 54 0.013
developmental maturation GO:0021700 193 0.013
Fly
regulation of wnt signaling pathway GO:0030111 123 0.013
ion transmembrane transport GO:0034220 361 0.013
regulation of reproductive process GO:2000241 66 0.013
dephosphorylation GO:0016311 129 0.013
mitochondrion organization GO:0007005 134 0.013
dna recombination GO:0006310 92 0.013
limb morphogenesis GO:0035108 149 0.013
neural tube formation GO:0001841 108 0.013
anion transport GO:0006820 177 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
glycerolipid metabolic process GO:0046486 122 0.013
negative regulation of mitotic cell cycle GO:0045930 58 0.013
Fly
response to organic cyclic compound GO:0014070 198 0.013
wnt signaling pathway GO:0016055 188 0.013
sensory organ morphogenesis GO:0090596 242 0.013
mrna splicing via spliceosome GO:0000398 43 0.013
single organism cell adhesion GO:0098602 156 0.013
chromatin silencing at rdna GO:0000183 3 0.013
negative regulation of protein maturation GO:1903318 79 0.013
multicellular organism growth GO:0035264 161 0.013
histone h4 k16 acetylation GO:0043984 3 0.013
cellular response to peptide GO:1901653 92 0.013
tissue homeostasis GO:0001894 115 0.013
actomyosin structure organization GO:0031032 56 0.013
protein ubiquitination GO:0016567 171 0.013
hexose metabolic process GO:0019318 98 0.013
chromatin organization GO:0006325 206 0.013
skeletal system development GO:0001501 356 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.012
stem cell maintenance GO:0019827 130 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.012
monosaccharide metabolic process GO:0005996 106 0.012
vesicle localization GO:0051648 86 0.012
rna splicing via transesterification reactions GO:0000375 43 0.012
positive regulation of proteolysis GO:0045862 85 0.012
renal system development GO:0072001 225 0.012
regulation of cellular protein catabolic process GO:1903362 61 0.012
extracellular matrix organization GO:0030198 147 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
carbohydrate homeostasis GO:0033500 128 0.012
myotube differentiation GO:0014902 105 0.012
activation of immune response GO:0002253 138 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.012
negative regulation of neuron death GO:1901215 98 0.012
primary neural tube formation GO:0014020 95 0.012
cardiac chamber development GO:0003205 108 0.012
myosin filament organization GO:0031033 3 0.012
cellular response to lipid GO:0071396 145 0.012
hindbrain development GO:0030902 128 0.012
regulation of cell growth GO:0001558 91 0.012
regulation of neuron differentiation GO:0045664 281 0.012
regulation of inflammatory response GO:0050727 147 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
regulation of metal ion transport GO:0010959 106 0.012
translation GO:0006412 93 0.012
glycoprotein metabolic process GO:0009100 116 0.012
mrna metabolic process GO:0016071 84 0.012
angiogenesis GO:0001525 201 0.012
rac protein signal transduction GO:0016601 13 0.012
oogenesis GO:0048477 56 0.012
Fly
regulation of vesicle mediated transport GO:0060627 139 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
regulation of homeostatic process GO:0032844 182 0.012
fucosylation GO:0036065 9 0.012
rhythmic process GO:0048511 174 0.012
negative regulation of cytokine production GO:0001818 84 0.012
l amino acid transport GO:0015807 32 0.012
mitotic g1 dna damage checkpoint GO:0031571 4 0.012
adaptive immune response GO:0002250 155 0.012
regulation of cellular component size GO:0032535 121 0.012
negative regulation of molecular function GO:0044092 258 0.012
regulation of striated muscle cell differentiation GO:0051153 81 0.012
placenta development GO:0001890 140 0.012
photoreceptor cell morphogenesis GO:0008594 3 0.012
regulation of adaptive immune response GO:0002819 90 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
single organismal cell cell adhesion GO:0016337 131 0.012
blastocyst growth GO:0001832 23 0.012
signal transduction involved in dna damage checkpoint GO:0072422 3 0.012
negative regulation of translational initiation GO:0045947 4 0.012
protein targeting GO:0006605 143 0.012
intestinal epithelial structure maintenance GO:0060729 4 0.012
positive regulation of peptidase activity GO:0010952 49 0.012
neuronal action potential GO:0019228 54 0.012
negative regulation of proteolysis GO:0045861 74 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
ossification GO:0001503 216 0.012
glial cell apoptotic process GO:0034349 3 0.012
blastocyst development GO:0001824 80 0.011
cofactor metabolic process GO:0051186 80 0.011
cytokinetic process GO:0032506 2 0.011
generation of precursor metabolites and energy GO:0006091 103 0.011
positive regulation of endopeptidase activity GO:0010950 43 0.011
nuclear dna replication GO:0033260 3 0.011
regulation of carbohydrate metabolic process GO:0006109 75 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.011
signal transduction involved in mitotic g1 dna damage checkpoint GO:0072431 3 0.011
alcohol metabolic process GO:0006066 116 0.011
midgut development GO:0007494 4 0.011
regulation of mitotic cell cycle phase transition GO:1901990 73 0.011
Fly
embryonic appendage morphogenesis GO:0035113 126 0.011
lipid localization GO:0010876 126 0.011
appendage morphogenesis GO:0035107 149 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001267 4 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
negative regulation of cell development GO:0010721 169 0.011
spindle assembly involved in mitosis GO:0090307 4 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
positive regulation of wnt signaling pathway GO:0030177 45 0.011
regulation of neuron death GO:1901214 134 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
locomotory behavior GO:0007626 195 0.011
stress activated protein kinase signaling cascade GO:0031098 81 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
organic acid biosynthetic process GO:0016053 86 0.011
response to extracellular stimulus GO:0009991 127 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.011
innate immune response GO:0045087 157 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
heart morphogenesis GO:0003007 178 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
positive regulation of growth GO:0045927 104 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
epithelial tube formation GO:0072175 130 0.011
regulation of cell motility GO:2000145 236 0.011
anatomical structure homeostasis GO:0060249 145 0.011
retrograde transport endosome to golgi GO:0042147 2 0.011
tube formation GO:0035148 140 0.011
regulation of system process GO:0044057 200 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
acylglycerol biosynthetic process GO:0046463 18 0.010
leukocyte activation involved in immune response GO:0002366 126 0.010
regulation of actin filament based process GO:0032970 99 0.010
response to inorganic substance GO:0010035 96 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
regulation of nucleoside metabolic process GO:0009118 130 0.010
single organism nuclear import GO:1902593 95 0.010
response to oxygen levels GO:0070482 62 0.010
regulation of cell size GO:0008361 72 0.010
glucose homeostasis GO:0042593 128 0.010
carboxylic acid catabolic process GO:0046395 51 0.010
regulation of t cell activation GO:0050863 170 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
negative regulation of cell cycle process GO:0010948 69 0.010
Fly
regulation of protein catabolic process GO:0042176 108 0.010
signal transduction in absence of ligand GO:0038034 55 0.010

E2f4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.033
disease of anatomical entity DOID:7 0 0.033
hematopoietic system disease DOID:74 0 0.026
bone marrow disease DOID:4961 0 0.023
musculoskeletal system disease DOID:17 0 0.021
muscular disease DOID:0080000 0 0.019
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
nervous system disease DOID:863 0 0.018
myopathy DOID:423 0 0.016
muscle tissue disease DOID:66 0 0.016
central nervous system disease DOID:331 0 0.015
congenital hypoplastic anemia DOID:1342 0 0.015
aplastic anemia DOID:12449 0 0.015
anemia DOID:2355 0 0.015
retinal disease DOID:5679 0 0.011
retinal degeneration DOID:8466 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011