Mus musculus

40 known processes

Klhl1

kelch-like 1 (Drosophila)

(Aliases: mKIAA1490,KIAA1490)

Klhl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 329 0.385
transmembrane transport GO:0055085 412 0.253
blood circulation GO:0008015 195 0.167
g protein coupled receptor signaling pathway GO:0007186 243 0.159
sensory perception GO:0007600 245 0.143
circulatory system process GO:0003013 197 0.137
organonitrogen compound biosynthetic process GO:1901566 192 0.135
locomotory behavior GO:0007626 195 0.123
membrane depolarization GO:0051899 64 0.115
regulation of neuron differentiation GO:0045664 281 0.111
action potential GO:0001508 78 0.106
cation transmembrane transport GO:0098655 266 0.102
regulation of membrane potential GO:0042391 192 0.101
cellular ketone metabolic process GO:0042180 84 0.097
retina development in camera type eye GO:0060041 119 0.089
heart process GO:0003015 94 0.088
axonogenesis GO:0007409 274 0.088
regulation of neuron death GO:1901214 134 0.087
regulation of blood circulation GO:1903522 93 0.087
purine ribonucleotide metabolic process GO:0009150 290 0.087
regulation of homeostatic process GO:0032844 182 0.085
sensory perception of sound GO:0007605 97 0.085
ribonucleotide metabolic process GO:0009259 291 0.083
ribose phosphate metabolic process GO:0019693 291 0.082
cellular amine metabolic process GO:0044106 44 0.082
nerve development GO:0021675 67 0.081
regulation of neuron projection development GO:0010975 169 0.079
organic hydroxy compound metabolic process GO:1901615 203 0.078
regulation of anatomical structure size GO:0090066 178 0.077
regulation of system process GO:0044057 200 0.075
stem cell differentiation GO:0048863 268 0.075
forebrain development GO:0030900 302 0.072
camera type eye development GO:0043010 266 0.070
multicellular organismal response to stress GO:0033555 62 0.069
learning GO:0007612 98 0.067
neuronal action potential GO:0019228 54 0.067
inorganic ion transmembrane transport GO:0098660 234 0.065
response to organonitrogen compound GO:0010243 246 0.065
learning or memory GO:0007611 148 0.064
cognition GO:0050890 149 0.063
skeletal system development GO:0001501 356 0.063
regulation of heart rate GO:0002027 36 0.062
nucleobase containing small molecule metabolic process GO:0055086 352 0.061
cation transport GO:0006812 399 0.061
oxidation reduction process GO:0055114 342 0.060
nucleoside phosphate metabolic process GO:0006753 338 0.059
regulation of action potential GO:0098900 4 0.058
regulation of purine nucleotide metabolic process GO:1900542 169 0.057
amine metabolic process GO:0009308 45 0.056
purine nucleotide metabolic process GO:0006163 302 0.056
heart contraction GO:0060047 93 0.056
nitrogen compound transport GO:0071705 271 0.056
inorganic cation transmembrane transport GO:0098662 207 0.056
multicellular organism growth GO:0035264 161 0.056
regulation of response to drug GO:2001023 2 0.056
purine containing compound metabolic process GO:0072521 311 0.054
regulation of cellular amine metabolic process GO:0033238 20 0.053
positive regulation of protein modification process GO:0031401 299 0.052
regulation of protein kinase activity GO:0045859 232 0.051
respiratory gaseous exchange GO:0007585 43 0.050
gliogenesis GO:0042063 141 0.050
telencephalon development GO:0021537 186 0.049
nucleotide metabolic process GO:0009117 332 0.049
sensory perception of mechanical stimulus GO:0050954 107 0.049
regulation of response to wounding GO:1903034 189 0.048
cell adhesion GO:0007155 329 0.048
cellular response to organonitrogen compound GO:0071417 145 0.048
clustering of voltage gated potassium channels GO:0045163 2 0.048
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.046
ossification GO:0001503 216 0.045
purine nucleoside catabolic process GO:0006152 205 0.045
positive regulation of protein phosphorylation GO:0001934 242 0.045
regulation of feeding behavior GO:0060259 3 0.045
sensory organ morphogenesis GO:0090596 242 0.044
leukocyte differentiation GO:0002521 342 0.044
regulation of nucleotide metabolic process GO:0006140 169 0.044
ribonucleoside metabolic process GO:0009119 245 0.044
ion transmembrane transport GO:0034220 361 0.044
heterocycle catabolic process GO:0046700 280 0.043
carbohydrate homeostasis GO:0033500 128 0.043
cellular nitrogen compound catabolic process GO:0044270 280 0.043
photoreceptor cell development GO:0042461 40 0.042
carbohydrate metabolic process GO:0005975 230 0.042
regulation of neuron apoptotic process GO:0043523 122 0.041
glial cell differentiation GO:0010001 131 0.041
regulation of blood vessel size GO:0050880 56 0.040
neuron neuron synaptic transmission GO:0007270 69 0.040
regulation of membrane depolarization GO:0003254 11 0.039
nucleotide biosynthetic process GO:0009165 78 0.039
regulation of ion transport GO:0043269 215 0.039
positive regulation of neuron differentiation GO:0045666 141 0.039
small gtpase mediated signal transduction GO:0007264 97 0.039
regulation of ion homeostasis GO:2000021 64 0.039
nucleoside phosphate biosynthetic process GO:1901293 79 0.038
neuron death GO:0070997 154 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.038
developmental maturation GO:0021700 193 0.038
regulation of cellular amino acid metabolic process GO:0006521 5 0.037
response to organic cyclic compound GO:0014070 198 0.037
stem cell development GO:0048864 219 0.037
organic cyclic compound catabolic process GO:1901361 295 0.037
glucose homeostasis GO:0042593 128 0.037
glycosyl compound catabolic process GO:1901658 206 0.037
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.037
blood vessel morphogenesis GO:0048514 285 0.037
regulation of cellular component size GO:0032535 121 0.036
organonitrogen compound catabolic process GO:1901565 264 0.036
eye photoreceptor cell development GO:0042462 31 0.036
central nervous system neuron differentiation GO:0021953 162 0.036
carbohydrate derivative biosynthetic process GO:1901137 183 0.036
eye photoreceptor cell differentiation GO:0001754 41 0.035
ear development GO:0043583 200 0.035
digestive tract development GO:0048565 190 0.035
negative regulation of cell development GO:0010721 169 0.035
aromatic compound catabolic process GO:0019439 286 0.035
purine containing compound biosynthetic process GO:0072522 70 0.033
nucleoside triphosphate catabolic process GO:0009143 205 0.033
muscle tissue development GO:0060537 308 0.033
multicellular organismal homeostasis GO:0048871 164 0.033
Mouse
regulation of mapk cascade GO:0043408 248 0.033
b cell activation GO:0042113 161 0.033
response to acid chemical GO:0001101 111 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.032
response to light stimulus GO:0009416 135 0.032
regulation of ossification GO:0030278 112 0.032
tissue remodeling GO:0048771 102 0.032
visual perception GO:0007601 52 0.032
mapk cascade GO:0000165 281 0.032
neuron migration GO:0001764 122 0.032
embryonic organ morphogenesis GO:0048562 276 0.031
glycosyl compound metabolic process GO:1901657 246 0.031
protein localization to juxtaparanode region of axon GO:0071205 4 0.031
neuron apoptotic process GO:0051402 142 0.031
hindbrain development GO:0030902 128 0.031
purine containing compound catabolic process GO:0072523 213 0.031
purine ribonucleotide catabolic process GO:0009154 208 0.031
regulation of organelle organization GO:0033043 289 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
multicellular organismal signaling GO:0035637 91 0.030
cell maturation GO:0048469 127 0.030
regulation of cell projection organization GO:0031344 206 0.030
regulation of kinase activity GO:0043549 249 0.030
sensory perception of pain GO:0019233 47 0.030
cellular amino acid metabolic process GO:0006520 103 0.030
regulation of glial cell differentiation GO:0045685 41 0.030
neuromuscular process GO:0050905 99 0.029
establishment of glial blood brain barrier GO:0060857 2 0.029
positive regulation of mapk cascade GO:0043410 170 0.029
anatomical structure homeostasis GO:0060249 145 0.029
Mouse
associative learning GO:0008306 61 0.029
chemotaxis GO:0006935 247 0.029
nerve maturation GO:0021682 1 0.029
diencephalon development GO:0021536 63 0.029
synaptic transmission glycinergic GO:0060012 2 0.029
purine nucleotide catabolic process GO:0006195 211 0.028
digestive system development GO:0055123 200 0.028
transmission of nerve impulse GO:0019226 76 0.028
positive regulation of neuron projection development GO:0010976 79 0.028
regulation of cell motility GO:2000145 236 0.028
morphogenesis of embryonic epithelium GO:0016331 159 0.028
ribonucleoside triphosphate catabolic process GO:0009203 199 0.028
negative regulation of neuron differentiation GO:0045665 101 0.028
ribonucleotide catabolic process GO:0009261 208 0.027
regulation of hydrolase activity GO:0051336 246 0.027
multi multicellular organism process GO:0044706 109 0.027
mechanoreceptor differentiation GO:0042490 67 0.027
regulation of synaptic plasticity GO:0048167 87 0.027
lipid biosynthetic process GO:0008610 179 0.027
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.027
negative regulation of neuron death GO:1901215 98 0.027
bone remodeling GO:0046849 53 0.027
cell type specific apoptotic process GO:0097285 268 0.027
guanosine containing compound metabolic process GO:1901068 144 0.026
organophosphate biosynthetic process GO:0090407 122 0.026
negative regulation of phosphate metabolic process GO:0045936 184 0.026
hormone secretion GO:0046879 128 0.026
negative regulation of intracellular signal transduction GO:1902532 167 0.026
Mouse
rhythmic process GO:0048511 174 0.026
calcium ion transport GO:0006816 159 0.026
ras protein signal transduction GO:0007265 77 0.026
regulation of blood pressure GO:0008217 93 0.026
dendrite development GO:0016358 115 0.026
monocarboxylic acid metabolic process GO:0032787 191 0.025
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.025
positive regulation of growth GO:0045927 104 0.025
neural retina development GO:0003407 41 0.025
regulation of postsynaptic membrane potential GO:0060078 48 0.025
cerebral cortex development GO:0021987 86 0.025
generation of ovulation cycle rhythm GO:0060112 1 0.025
purine nucleoside metabolic process GO:0042278 241 0.025
lymphocyte differentiation GO:0030098 242 0.025
purine ribonucleoside metabolic process GO:0046128 241 0.025
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.025
angiogenesis GO:0001525 201 0.025
peptide secretion GO:0002790 114 0.024
respiratory system development GO:0060541 190 0.024
tissue homeostasis GO:0001894 115 0.024
Mouse
regulation of cell migration GO:0030334 219 0.024
fear response GO:0042596 33 0.024
nucleotide catabolic process GO:0009166 217 0.024
response to radiation GO:0009314 165 0.024
regulation of transferase activity GO:0051338 263 0.023
gtp metabolic process GO:0046039 144 0.023
synapse organization GO:0050808 125 0.023
response to amino acid GO:0043200 37 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
response to oxygen levels GO:0070482 62 0.023
neural precursor cell proliferation GO:0061351 121 0.023
connective tissue development GO:0061448 179 0.023
mitochondrion organization GO:0007005 134 0.023
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.023
nucleoside metabolic process GO:0009116 246 0.022
cytokine production GO:0001816 319 0.022
lipid transport GO:0006869 98 0.022
positive regulation of nervous system development GO:0051962 221 0.022
membrane organization GO:0061024 245 0.022
rho protein signal transduction GO:0007266 32 0.022
photoreceptor cell differentiation GO:0046530 52 0.022
cellular chemical homeostasis GO:0055082 215 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.022
divalent inorganic cation transport GO:0072511 178 0.022
organophosphate catabolic process GO:0046434 232 0.022
neuromuscular process controlling posture GO:0050884 14 0.021
cellular component assembly involved in morphogenesis GO:0010927 139 0.021
cellular carbohydrate metabolic process GO:0044262 119 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
cyclic purine nucleotide metabolic process GO:0052652 43 0.021
cerebellum development GO:0021549 77 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
cerebellar granule cell precursor proliferation GO:0021930 10 0.021
acetylcholine transport GO:0015870 2 0.021
norepinephrine secretion GO:0048243 2 0.021
respiratory system process GO:0003016 25 0.021
cellular lipid metabolic process GO:0044255 323 0.021
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
inner ear receptor cell differentiation GO:0060113 61 0.020
cell fate commitment GO:0045165 210 0.020
immune effector process GO:0002252 321 0.020
protein localization to membrane GO:0072657 108 0.020
cardiac chamber development GO:0003205 108 0.020
myelination GO:0042552 74 0.020
pallium development GO:0021543 120 0.020
regulation of proteolysis GO:0030162 164 0.020
organic hydroxy compound biosynthetic process GO:1901617 77 0.020
cell proliferation in external granule layer GO:0021924 10 0.020
developmental growth involved in morphogenesis GO:0060560 138 0.020
purine nucleotide biosynthetic process GO:0006164 65 0.020
detection of stimulus involved in sensory perception GO:0050906 44 0.020
regionalization GO:0003002 337 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
multi organism behavior GO:0051705 62 0.020
regulation of secretion by cell GO:1903530 249 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
catecholamine metabolic process GO:0006584 30 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.019
positive regulation of kinase activity GO:0033674 155 0.019
regulation of multi organism process GO:0043900 111 0.019
negative regulation of action potential GO:0045759 1 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
limb morphogenesis GO:0035108 149 0.019
regulation of cell activation GO:0050865 289 0.019
skeletal system morphogenesis GO:0048705 203 0.019
neuron maturation GO:0042551 29 0.019
regulation of nucleoside metabolic process GO:0009118 130 0.019
ribose phosphate biosynthetic process GO:0046390 59 0.019
norepinephrine transport GO:0015874 2 0.019
cyclic nucleotide metabolic process GO:0009187 59 0.019
cranial nerve development GO:0021545 41 0.018
guanosine containing compound catabolic process GO:1901069 144 0.018
dopamine metabolic process GO:0042417 23 0.018
amino acid transport GO:0006865 61 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
spinal cord development GO:0021510 81 0.018
carboxylic acid transport GO:0046942 100 0.018
cellular response to organic cyclic compound GO:0071407 87 0.018
telencephalon cell migration GO:0022029 55 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
thalamus development GO:0021794 11 0.018
amide transport GO:0042886 138 0.018
positive regulation of secretion by cell GO:1903532 114 0.018
cation homeostasis GO:0055080 212 0.018
regulation of heart contraction GO:0008016 77 0.018
positive regulation of secretion GO:0051047 130 0.018
calcium ion transmembrane transport GO:0070588 85 0.018
regulation of leukocyte differentiation GO:1902105 159 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
positive regulation of dopamine secretion GO:0033603 2 0.018
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.017
central nervous system neuron development GO:0021954 67 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
purine ribonucleotide biosynthetic process GO:0009152 59 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
detection of stimulus GO:0051606 84 0.017
cellular homeostasis GO:0019725 240 0.017
second messenger mediated signaling GO:0019932 73 0.017
regulation of cytokine production GO:0001817 266 0.017
phenol containing compound metabolic process GO:0018958 60 0.017
intracellular distribution of mitochondria GO:0048312 1 0.017
muscle cell differentiation GO:0042692 261 0.017
regulation of gtp catabolic process GO:0033124 113 0.017
limbic system development GO:0021761 72 0.017
striated muscle tissue development GO:0014706 293 0.017
epithelial cell proliferation GO:0050673 174 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
regulation of cell size GO:0008361 72 0.017
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.017
spermatid development GO:0007286 108 0.017
Mouse
acetylcholine secretion neurotransmission GO:0014055 2 0.017
detection of abiotic stimulus GO:0009582 60 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.016
sa node cell action potential GO:0086015 4 0.016
regulation of cytoskeleton organization GO:0051493 122 0.016
regulation of cell growth GO:0001558 91 0.016
positive regulation of transferase activity GO:0051347 167 0.016
cellular response to ammonium ion GO:0071242 2 0.016
endocrine system development GO:0035270 98 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.016
ensheathment of neurons GO:0007272 76 0.016
urogenital system development GO:0001655 261 0.016
inter male aggressive behavior GO:0002121 3 0.016
innervation GO:0060384 22 0.016
regulation of epithelial cell proliferation GO:0050678 141 0.016
cerebral cortex neuron differentiation GO:0021895 19 0.016
synapse assembly GO:0007416 56 0.016
response to peptide GO:1901652 136 0.016
ameboidal type cell migration GO:0001667 128 0.016
cardiac muscle cell contraction GO:0086003 7 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
divalent metal ion transport GO:0070838 172 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
response to growth factor GO:0070848 198 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
phenol containing compound biosynthetic process GO:0046189 21 0.015
segmentation GO:0035282 93 0.015
glucose metabolic process GO:0006006 92 0.015
homeostasis of number of cells GO:0048872 210 0.015
Mouse
negative regulation of nervous system development GO:0051961 156 0.015
innate immune response GO:0045087 157 0.015
rna processing GO:0006396 105 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
Mouse
gtp catabolic process GO:0006184 143 0.015
neuron projection guidance GO:0097485 141 0.015
inflammatory response GO:0006954 244 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.015
lipid localization GO:0010876 126 0.015
mesenchymal cell development GO:0014031 93 0.015
cellular protein complex assembly GO:0043623 116 0.015
camp biosynthetic process GO:0006171 31 0.015
epithelial cell development GO:0002064 159 0.015
l amino acid transport GO:0015807 32 0.015
adult behavior GO:0030534 135 0.015
bone development GO:0060348 120 0.015
dna metabolic process GO:0006259 303 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
peptide hormone secretion GO:0030072 109 0.015
extracellular matrix organization GO:0030198 147 0.015
metal ion homeostasis GO:0055065 189 0.015
mesenchyme development GO:0060485 152 0.015
retina morphogenesis in camera type eye GO:0060042 45 0.015
positive regulation of cell development GO:0010720 237 0.015
adult locomotory behavior GO:0008344 91 0.015
protein ubiquitination GO:0016567 171 0.015
actin mediated cell contraction GO:0070252 15 0.015
neural tube development GO:0021915 160 0.015
response to histamine GO:0034776 1 0.015
palate development GO:0060021 76 0.015
central nervous system maturation GO:0021626 6 0.014
vascular process in circulatory system GO:0003018 62 0.014
hexose transport GO:0008645 56 0.014
regulation of tube size GO:0035150 57 0.014
cardiac muscle tissue development GO:0048738 130 0.014
l alpha amino acid transmembrane transport GO:1902475 23 0.014
adult walking behavior GO:0007628 41 0.014
gastrulation GO:0007369 116 0.014
microtubule based process GO:0007017 236 0.014
monosaccharide transport GO:0015749 58 0.014
b cell differentiation GO:0030183 78 0.014
protein polymerization GO:0051258 57 0.014
sensory perception of light stimulus GO:0050953 54 0.014
organic anion transport GO:0015711 137 0.014
neural tube formation GO:0001841 108 0.014
gland development GO:0048732 330 0.014
glucose transport GO:0015758 56 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
response to nutrient levels GO:0031667 109 0.014
compound eye development GO:0048749 1 0.014
negative regulation of neuron apoptotic process GO:0043524 92 0.014
detection of external stimulus GO:0009581 61 0.014
muscle cell development GO:0055001 133 0.014
response to peptide hormone GO:0043434 127 0.014
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 3 0.014
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.014
adaptive immune response GO:0002250 155 0.014
chromatin modification GO:0016568 187 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.014
wnt signaling pathway GO:0016055 188 0.014
response to oxidative stress GO:0006979 123 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
regulation of norepinephrine secretion GO:0014061 2 0.014
positive regulation of protein kinase activity GO:0045860 144 0.013
embryonic placenta development GO:0001892 98 0.013
mesenchymal cell differentiation GO:0048762 107 0.013
feeding behavior GO:0007631 62 0.013
leukocyte mediated immunity GO:0002443 174 0.013
negative regulation of response to wounding GO:1903035 77 0.013
regulation of gliogenesis GO:0014013 50 0.013
stem cell maintenance GO:0019827 130 0.013
cellular response to glucose stimulus GO:0071333 45 0.013
conditioned taste aversion GO:0001661 4 0.013
neuron recognition GO:0008038 25 0.013
synaptic transmission involved in micturition GO:0060084 3 0.013
immune response regulating signaling pathway GO:0002764 125 0.013
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.013
peptidyl amino acid modification GO:0018193 336 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
regulation of defense response GO:0031347 233 0.013
carbohydrate transport GO:0008643 62 0.013
baroreceptor response to decreased systemic arterial blood pressure GO:0001982 2 0.013
regulation of interleukin 6 production GO:0032675 55 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
response to inorganic substance GO:0010035 96 0.013
positive regulation of catecholamine secretion GO:0033605 2 0.013
macromolecule catabolic process GO:0009057 281 0.013
circadian sleep wake cycle rem sleep GO:0042747 1 0.013
tube formation GO:0035148 140 0.013
cyclic nucleotide biosynthetic process GO:0009190 44 0.013
cellular response to lipid GO:0071396 145 0.013
negative regulation of organelle organization GO:0010639 90 0.013
ribonucleotide biosynthetic process GO:0009260 59 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
bone resorption GO:0045453 38 0.013
t cell activation GO:0042110 289 0.013
neural tube closure GO:0001843 90 0.013
regulation of erk1 and erk2 cascade GO:0070372 71 0.013
regulation of hormone secretion GO:0046883 88 0.013
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.013
cellularization GO:0007349 1 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
regulation of auditory receptor cell differentiation GO:0045607 4 0.013
axon guidance GO:0007411 141 0.012
regulation of protein kinase b signaling GO:0051896 56 0.012
rhodopsin mediated signaling pathway GO:0016056 4 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
regulation of inflammatory response GO:0050727 147 0.012
regulation of protein complex disassembly GO:0043244 28 0.012
male gamete generation GO:0048232 285 0.012
Mouse
endocytosis GO:0006897 168 0.012
developmental cell growth GO:0048588 84 0.012
protein secretion GO:0009306 111 0.012
organ growth GO:0035265 117 0.012
camp metabolic process GO:0046058 40 0.012
regulation of protein complex assembly GO:0043254 83 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
reflex GO:0060004 22 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
astrocyte differentiation GO:0048708 43 0.012
response to pain GO:0048265 26 0.012
digestive tract morphogenesis GO:0048546 147 0.012
cell proliferation in hindbrain GO:0021534 10 0.012
organic hydroxy compound transport GO:0015850 93 0.012
cell growth GO:0016049 130 0.012
calcium ion dependent exocytosis GO:0017156 35 0.012
single organism cell adhesion GO:0098602 156 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
dephosphorylation GO:0016311 129 0.012
placenta development GO:0001890 140 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
internal peptidyl lysine acetylation GO:0018393 42 0.012
sodium ion transmembrane transport GO:0035725 49 0.012
acetate ester transport GO:1901374 2 0.012
central nervous system neuron axonogenesis GO:0021955 28 0.012
pancreatic pp cell differentiation GO:0003312 2 0.012
apoptotic signaling pathway GO:0097190 306 0.012
Mouse
membrane depolarization during sa node cell action potential GO:0086046 2 0.012
regulation of neural retina development GO:0061074 3 0.012
mitochondrion distribution GO:0048311 4 0.012
mesodermal cell migration GO:0008078 4 0.012
cytoplasmic transport GO:0016482 234 0.012
negative regulation of ossification GO:0030279 49 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
embryonic epithelial tube formation GO:0001838 130 0.012
myeloid leukocyte differentiation GO:0002573 119 0.011
muscle contraction GO:0006936 101 0.011

Klhl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.033
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033
eye and adnexa disease DOID:1492 0 0.025
eye disease DOID:5614 0 0.025
musculoskeletal system disease DOID:17 0 0.019
disease of cellular proliferation DOID:14566 0 0.012
retinal disease DOID:5679 0 0.012
retinal degeneration DOID:8466 0 0.012
cancer DOID:162 0 0.012