Mus musculus

49 known processes

Ptgs1

prostaglandin-endoperoxide synthase 1

(Aliases: Pghs1,COX1,Cox-1,Cox-3)

Ptgs1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
inflammatory response GO:0006954 244 0.571
Mouse
cellular amine metabolic process GO:0044106 44 0.523
synaptic transmission GO:0007268 329 0.397
regulation of cell migration GO:0030334 219 0.337
regulation of protein transport GO:0051223 163 0.323
amine metabolic process GO:0009308 45 0.319
circulatory system process GO:0003013 197 0.242
angiogenesis GO:0001525 201 0.240
negative regulation of cellular protein metabolic process GO:0032269 247 0.234
regulation of system process GO:0044057 200 0.234
Rat
leukocyte migration GO:0050900 124 0.232
monocarboxylic acid metabolic process GO:0032787 191 0.232
regulation of cell motility GO:2000145 236 0.228
regulation of transferase activity GO:0051338 263 0.224
fatty acid metabolic process GO:0006631 121 0.215
glomerulus development GO:0032835 40 0.213
cell substrate adhesion GO:0031589 130 0.213
response to molecule of bacterial origin GO:0002237 143 0.209
oxidation reduction process GO:0055114 342 0.208
Human Zebrafish Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.207
cell adhesion GO:0007155 329 0.206
gland development GO:0048732 330 0.202
cellular amino acid metabolic process GO:0006520 103 0.201
cytokine production GO:0001816 319 0.197
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.195
response to lipopolysaccharide GO:0032496 128 0.195
chemotaxis GO:0006935 247 0.194
positive regulation of cell migration GO:0030335 109 0.185
regulation of hormone levels GO:0010817 211 0.174
Rat
cellular ketone metabolic process GO:0042180 84 0.174
regulation of anatomical structure size GO:0090066 178 0.169
Rat
regulation of kinase activity GO:0043549 249 0.169
hemostasis GO:0007599 78 0.169
ion transmembrane transport GO:0034220 361 0.168
negative regulation of protein metabolic process GO:0051248 282 0.168
wound healing GO:0042060 157 0.163
regulation of cellular ketone metabolic process GO:0010565 66 0.161
regulation of organelle organization GO:0033043 289 0.159
mapk cascade GO:0000165 281 0.153
glycosyl compound metabolic process GO:1901657 246 0.151
icosanoid biosynthetic process GO:0046456 15 0.150
renal system process GO:0003014 48 0.148
transmembrane transport GO:0055085 412 0.147
regulation of inflammatory response GO:0050727 147 0.140
Mouse
cellular response to biotic stimulus GO:0071216 92 0.138
muscle system process GO:0003012 141 0.137
Rat
striated muscle tissue development GO:0014706 293 0.136
urogenital system development GO:0001655 261 0.134
Zebrafish
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.131
unsaturated fatty acid metabolic process GO:0033559 31 0.131
regulation of cellular amino acid metabolic process GO:0006521 5 0.130
fatty acid derivative metabolic process GO:1901568 33 0.128
leukocyte differentiation GO:0002521 342 0.124
negative regulation of protein modification process GO:0031400 163 0.123
negative regulation of phosphorylation GO:0042326 166 0.122
nucleoside metabolic process GO:0009116 246 0.122
regulation of intracellular transport GO:0032386 159 0.122
kidney development GO:0001822 213 0.122
Zebrafish
blood circulation GO:0008015 195 0.121
protein localization to nucleus GO:0034504 121 0.121
cation transport GO:0006812 399 0.120
actin cytoskeleton organization GO:0030036 220 0.119
nitrogen compound transport GO:0071705 271 0.119
Rat
carboxylic acid biosynthetic process GO:0046394 86 0.118
regulation of mapk cascade GO:0043408 248 0.118
response to growth factor GO:0070848 198 0.117
positive regulation of protein transport GO:0051222 93 0.117
response to peptide hormone GO:0043434 127 0.117
regulation of hydrolase activity GO:0051336 246 0.116
negative regulation of protein phosphorylation GO:0001933 126 0.113
regulation of cellular response to growth factor stimulus GO:0090287 82 0.112
intracellular protein transport GO:0006886 204 0.112
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.110
positive regulation of vasoconstriction GO:0045907 4 0.109
Rat
regulation of cell activation GO:0050865 289 0.107
acute inflammatory response GO:0002526 41 0.105
Mouse
cellular lipid metabolic process GO:0044255 323 0.104
aromatic compound catabolic process GO:0019439 286 0.103
response to inorganic substance GO:0010035 96 0.103
small molecule biosynthetic process GO:0044283 132 0.102
camera type eye development GO:0043010 266 0.099
vascular process in circulatory system GO:0003018 62 0.098
Rat
regulation of protein kinase activity GO:0045859 232 0.098
positive regulation of programmed cell death GO:0043068 218 0.098
regulation of muscle system process GO:0090257 80 0.097
Rat
positive regulation of protein modification process GO:0031401 299 0.097
morphogenesis of a branching structure GO:0001763 203 0.097
male gamete generation GO:0048232 285 0.097
negative regulation of phosphorus metabolic process GO:0010563 184 0.095
coagulation GO:0050817 78 0.095
positive regulation of defense response GO:0031349 124 0.093
Mouse
organic anion transport GO:0015711 137 0.093
regulation of secretion GO:0051046 274 0.092
Rat
regulation of protein localization GO:0032880 231 0.091
endocytosis GO:0006897 168 0.091
organonitrogen compound catabolic process GO:1901565 264 0.090
positive regulation of mapk cascade GO:0043410 170 0.089
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.089
regulation of vasculature development GO:1901342 88 0.088
lipid transport GO:0006869 98 0.088
immune effector process GO:0002252 321 0.085
single organism cell adhesion GO:0098602 156 0.085
positive regulation of proteolysis GO:0045862 85 0.084
g protein coupled receptor signaling pathway GO:0007186 243 0.084
prostaglandin metabolic process GO:0006693 11 0.084
peptidyl amino acid modification GO:0018193 336 0.084
regulation of cytokine production GO:0001817 266 0.083
divalent inorganic cation transport GO:0072511 178 0.083
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.083
peptide transport GO:0015833 133 0.083
regulation of actin filament based process GO:0032970 99 0.082
cellular response to cytokine stimulus GO:0071345 189 0.080
divalent metal ion transport GO:0070838 172 0.080
kidney epithelium development GO:0072073 121 0.079
response to organonitrogen compound GO:0010243 246 0.079
Rat
muscle tissue development GO:0060537 308 0.078
regulation of protein localization to nucleus GO:1900180 60 0.078
positive regulation of transferase activity GO:0051347 167 0.078
purine containing compound metabolic process GO:0072521 311 0.078
positive regulation of apoptotic process GO:0043065 217 0.078
smooth muscle contraction GO:0006939 44 0.077
Rat
spermatogenesis GO:0007283 284 0.077
ribonucleoside metabolic process GO:0009119 245 0.076
positive regulation of cellular amine metabolic process GO:0033240 5 0.075
sprouting angiogenesis GO:0002040 26 0.075
erk1 and erk2 cascade GO:0070371 77 0.075
purine nucleoside metabolic process GO:0042278 241 0.074
amide transport GO:0042886 138 0.074
cellular response to lipid GO:0071396 145 0.074
regulation of cellular amine metabolic process GO:0033238 20 0.073
reactive nitrogen species metabolic process GO:2001057 0 0.073
ras protein signal transduction GO:0007265 77 0.073
purine nucleoside triphosphate metabolic process GO:0009144 226 0.072
renal system development GO:0072001 225 0.072
Zebrafish
inorganic ion transmembrane transport GO:0098660 234 0.071
ribose phosphate metabolic process GO:0019693 291 0.071
positive regulation of cell death GO:0010942 224 0.070
anion transport GO:0006820 177 0.070
actin filament organization GO:0007015 113 0.070
icosanoid metabolic process GO:0006690 33 0.070
rhythmic process GO:0048511 174 0.069
nucleoside phosphate metabolic process GO:0006753 338 0.069
fatty acid biosynthetic process GO:0006633 41 0.069
epithelial tube morphogenesis GO:0060562 303 0.068
membrane organization GO:0061024 245 0.068
regulation of establishment of protein localization GO:0070201 181 0.068
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.067
lipid biosynthetic process GO:0008610 179 0.067
nephron development GO:0072006 109 0.067
carbohydrate derivative catabolic process GO:1901136 231 0.067
metanephric glomerular mesangium development GO:0072223 3 0.067
regulation of blood vessel size GO:0050880 56 0.067
Rat
epithelial cell migration GO:0010631 63 0.067
cellular response to molecule of bacterial origin GO:0071219 83 0.067
response to acid chemical GO:0001101 111 0.066
Rat
regulation of cell adhesion GO:0030155 154 0.066
heart process GO:0003015 94 0.065
regulation of defense response GO:0031347 233 0.065
Mouse
purine nucleoside catabolic process GO:0006152 205 0.065
neutrophil migration GO:1990266 37 0.065
positive regulation of cell activation GO:0050867 158 0.065
negative regulation of molecular function GO:0044092 258 0.063
nephron epithelium development GO:0072009 92 0.063
organic acid biosynthetic process GO:0016053 86 0.063
metanephric nephron development GO:0072210 34 0.062
sensory perception GO:0007600 245 0.062
Rat
lymphocyte differentiation GO:0030098 242 0.061
tissue remodeling GO:0048771 102 0.061
metal ion homeostasis GO:0055065 189 0.061
nucleoside catabolic process GO:0009164 206 0.061
reactive oxygen species biosynthetic process GO:1903409 8 0.061
cellular response to growth factor stimulus GO:0071363 197 0.060
negative regulation of cytokine production GO:0001818 84 0.060
regulation of homeostatic process GO:0032844 182 0.059
Mouse
cellular response to peptide GO:1901653 92 0.059
rho protein signal transduction GO:0007266 32 0.059
regulation of peptidase activity GO:0052547 96 0.058
cytokine mediated signaling pathway GO:0019221 115 0.058
positive regulation of cell motility GO:2000147 116 0.058
regulation of cytoskeleton organization GO:0051493 122 0.058
cellular homeostasis GO:0019725 240 0.058
positive regulation of cell adhesion GO:0045785 80 0.057
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.057
monocarboxylic acid biosynthetic process GO:0072330 61 0.057
positive regulation of angiogenesis GO:0045766 46 0.057
regulation of ion transport GO:0043269 215 0.057
response to peptide GO:1901652 136 0.056
regulation of circadian sleep wake cycle GO:0042749 3 0.056
cellular calcium ion homeostasis GO:0006874 119 0.056
renal tubule development GO:0061326 87 0.056
regulation of cell cycle GO:0051726 281 0.056
muscle cell differentiation GO:0042692 261 0.055
protein maturation GO:0051604 176 0.055
cellular metal ion homeostasis GO:0006875 151 0.055
response to nutrient levels GO:0031667 109 0.055
cellular nitrogen compound catabolic process GO:0044270 280 0.054
regulation of epithelial cell proliferation GO:0050678 141 0.054
regulation of angiogenesis GO:0045765 81 0.054
dna metabolic process GO:0006259 303 0.054
positive regulation of kinase activity GO:0033674 155 0.053
skin development GO:0043588 220 0.053
Mouse
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.053
organophosphate catabolic process GO:0046434 232 0.053
muscle contraction GO:0006936 101 0.052
Rat
inorganic cation transmembrane transport GO:0098662 207 0.052
granulocyte migration GO:0097530 43 0.052
t cell differentiation GO:0030217 174 0.052
reactive oxygen species metabolic process GO:0072593 84 0.052
nucleotide catabolic process GO:0009166 217 0.052
purine nucleoside triphosphate catabolic process GO:0009146 203 0.051
positive regulation of protein phosphorylation GO:0001934 242 0.050
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.049
germ cell development GO:0007281 185 0.049
organic hydroxy compound transport GO:0015850 93 0.049
Rat
positive regulation of hydrolase activity GO:0051345 148 0.048
neuronal action potential GO:0019228 54 0.048
peptide secretion GO:0002790 114 0.048
visual perception GO:0007601 52 0.048
regulation of muscle contraction GO:0006937 49 0.048
Rat
sensory perception of light stimulus GO:0050953 54 0.048
response to metal ion GO:0010038 47 0.047
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.047
nucleobase containing small molecule metabolic process GO:0055086 352 0.047
locomotory behavior GO:0007626 195 0.047
negative regulation of inflammatory response GO:0050728 61 0.047
liver development GO:0001889 66 0.047
positive regulation of intracellular protein transport GO:0090316 42 0.046
protein localization to organelle GO:0033365 185 0.046
negative regulation of response to wounding GO:1903035 77 0.046
regulation of intracellular protein transport GO:0033157 82 0.046
protein import into nucleus GO:0006606 95 0.045
regulation of response to wounding GO:1903034 189 0.045
Mouse
cellular response to dna damage stimulus GO:0006974 207 0.045
regulation of apoptotic signaling pathway GO:2001233 197 0.045
purine nucleotide metabolic process GO:0006163 302 0.045
regulation of ion transmembrane transport GO:0034765 119 0.045
regulation of tube size GO:0035150 57 0.045
Rat
epidermis development GO:0008544 187 0.044
Mouse
negative regulation of hydrolase activity GO:0051346 71 0.044
t cell activation GO:0042110 289 0.044
regulation of heart contraction GO:0008016 77 0.044
regulation of blood circulation GO:1903522 93 0.044
Rat
action potential GO:0001508 78 0.044
jnk cascade GO:0007254 72 0.043
cation transmembrane transport GO:0098655 266 0.043
cell matrix adhesion GO:0007160 68 0.043
fatty acid derivative biosynthetic process GO:1901570 15 0.043
leukocyte activation involved in immune response GO:0002366 126 0.043
kidney vasculature development GO:0061440 15 0.043
divalent inorganic cation homeostasis GO:0072507 138 0.043
anatomical structure homeostasis GO:0060249 145 0.043
fat cell differentiation GO:0045444 160 0.043
Mouse
mitotic cytokinesis GO:0000281 4 0.043
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.043
learning GO:0007612 98 0.042
Rat
regulation of peptidyl serine phosphorylation GO:0033135 39 0.042
regulation of reactive oxygen species metabolic process GO:2000377 40 0.042
multicellular organismal signaling GO:0035637 91 0.042
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.042
purine ribonucleotide metabolic process GO:0009150 290 0.042
peptidyl tyrosine modification GO:0018212 145 0.042
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.042
regulation of cellular component size GO:0032535 121 0.042
carboxylic acid transport GO:0046942 100 0.042
regulation of wnt signaling pathway GO:0030111 123 0.041
negative regulation of defense response GO:0031348 77 0.041
carbohydrate metabolic process GO:0005975 230 0.041
organophosphate biosynthetic process GO:0090407 122 0.041
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.041
chemokine production GO:0032602 34 0.041
cell chemotaxis GO:0060326 81 0.041
respiratory system development GO:0060541 190 0.041
unsaturated fatty acid biosynthetic process GO:0006636 15 0.041
response to monosaccharide GO:0034284 67 0.041
regulation of acute inflammatory response GO:0002673 27 0.041
Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.040
negative regulation of cell proliferation GO:0008285 296 0.040
response to drug GO:0042493 75 0.040
protein targeting GO:0006605 143 0.040
response to extracellular stimulus GO:0009991 127 0.040
nucleotide metabolic process GO:0009117 332 0.040
positive regulation of map kinase activity GO:0043406 84 0.040
engulfment of apoptotic cell GO:0043652 3 0.039
neuron neuron synaptic transmission GO:0007270 69 0.039
regulation of membrane potential GO:0042391 192 0.039
apoptotic signaling pathway GO:0097190 306 0.039
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.039
hematopoietic progenitor cell differentiation GO:0002244 143 0.039
blood coagulation GO:0007596 76 0.039
organic hydroxy compound metabolic process GO:1901615 203 0.039
homeostasis of number of cells GO:0048872 210 0.039
metanephric glomerulus development GO:0072224 13 0.039
glycosyl compound catabolic process GO:1901658 206 0.038
nuclear import GO:0051170 95 0.038
regulation of cell projection organization GO:0031344 206 0.038
regulation of chemokine secretion GO:0090196 4 0.038
positive regulation of apoptotic signaling pathway GO:2001235 95 0.038
regulation of map kinase activity GO:0043405 120 0.038
negative regulation of intracellular signal transduction GO:1902532 167 0.038
male gonad development GO:0008584 88 0.037
negative regulation of proteolysis GO:0045861 74 0.037
purine ribonucleoside catabolic process GO:0046130 205 0.037
blood vessel morphogenesis GO:0048514 285 0.037
Zebrafish
cellular response to hormone stimulus GO:0032870 150 0.037
cytoplasmic transport GO:0016482 234 0.037
leukocyte mediated immunity GO:0002443 174 0.037
cellular response to extracellular stimulus GO:0031668 81 0.037
transmission of nerve impulse GO:0019226 76 0.037
epithelium migration GO:0090132 63 0.037
cellular component assembly involved in morphogenesis GO:0010927 139 0.036
organic acid transport GO:0015849 101 0.036
protein processing GO:0016485 163 0.036
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.036
vasoconstriction GO:0042310 27 0.036
Rat
nephron tubule development GO:0072080 84 0.036
single organismal cell cell adhesion GO:0016337 131 0.036
macromolecule catabolic process GO:0009057 281 0.036
skeletal muscle organ development GO:0060538 163 0.036
positive regulation of intracellular transport GO:0032388 70 0.035
regulation of reproductive process GO:2000241 66 0.035
organonitrogen compound biosynthetic process GO:1901566 192 0.035
regulation of feeding behavior GO:0060259 3 0.035
metanephros development GO:0001656 79 0.035
response to insulin GO:0032868 100 0.035
cation homeostasis GO:0055080 212 0.035
regulation of cellular component biogenesis GO:0044087 181 0.035
ribonucleotide catabolic process GO:0009261 208 0.034
ribonucleoside catabolic process GO:0042454 206 0.034
positive regulation of secretion GO:0051047 130 0.034
extrinsic apoptotic signaling pathway GO:0097191 126 0.034
sensory perception of pain GO:0019233 47 0.034
Rat
heart morphogenesis GO:0003007 178 0.034
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.034
positive regulation of homeostatic process GO:0032846 64 0.034
Mouse
peptidyl serine phosphorylation GO:0018105 74 0.033
regulation of fat cell differentiation GO:0045598 81 0.033
Mouse
regulation of cell substrate adhesion GO:0010810 73 0.033
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.033
positive regulation of cell substrate adhesion GO:0010811 47 0.033
cellular chemical homeostasis GO:0055082 215 0.033
regulation of protein catabolic process GO:0042176 108 0.033
cellular divalent inorganic cation homeostasis GO:0072503 127 0.032
regulation of interleukin 8 production GO:0032677 3 0.032
angiotensin activated signaling pathway GO:0038166 4 0.032
regulation of metal ion transport GO:0010959 106 0.032
interleukin 8 production GO:0032637 4 0.032
purine containing compound catabolic process GO:0072523 213 0.032
wnt signaling pathway GO:0016055 188 0.032
stem cell differentiation GO:0048863 268 0.032
regulation of lymphocyte activation GO:0051249 240 0.032
defecation GO:0030421 1 0.031
ensheathment of neurons GO:0007272 76 0.031
carbohydrate derivative biosynthetic process GO:1901137 183 0.031
canonical wnt signaling pathway GO:0060070 130 0.031
muscle cell development GO:0055001 133 0.031
cytokine production involved in immune response GO:0002367 34 0.031
regulation of adrenergic receptor signaling pathway GO:0071877 4 0.031
skeletal system development GO:0001501 356 0.031
positive regulation of protein localization to nucleus GO:1900182 30 0.031
peptidyl tyrosine phosphorylation GO:0018108 143 0.031
i kappab kinase nf kappab signaling GO:0007249 85 0.031
leukocyte chemotaxis GO:0030595 69 0.031
endothelial cell migration GO:0043542 44 0.031
carbohydrate homeostasis GO:0033500 128 0.031
immune response regulating signaling pathway GO:0002764 125 0.030
organic hydroxy compound biosynthetic process GO:1901617 77 0.030
establishment of protein localization to organelle GO:0072594 118 0.030
mitotic cell cycle GO:0000278 195 0.030
ribonucleoside triphosphate metabolic process GO:0009199 220 0.030
activation of innate immune response GO:0002218 56 0.030
regulation of protein maturation GO:1903317 96 0.030
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.030
positive regulation of brown fat cell differentiation GO:0090336 4 0.030
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.030
cellular response to external stimulus GO:0071496 88 0.030
nucleoside triphosphate metabolic process GO:0009141 230 0.030
positive regulation of cytoplasmic transport GO:1903651 40 0.030
regulation of protein secretion GO:0050708 82 0.030
regulation of blood pressure GO:0008217 93 0.030
regulation of chemotaxis GO:0050920 53 0.029
production of molecular mediator of immune response GO:0002440 103 0.029
positive regulation of nucleotide catabolic process GO:0030813 88 0.029
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.029
endomembrane system organization GO:0010256 147 0.029
regulation of leukocyte differentiation GO:1902105 159 0.029
axonogenesis GO:0007409 274 0.029
regulation of ossification GO:0030278 112 0.029
ossification GO:0001503 216 0.029
positive regulation of cytokine production GO:0001819 174 0.028
ribonucleoside triphosphate catabolic process GO:0009203 199 0.028
forebrain development GO:0030900 302 0.028
regulation of actin cytoskeleton organization GO:0032956 84 0.028
positive regulation of nucleotide metabolic process GO:0045981 114 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.028
positive regulation of dna biosynthetic process GO:2000573 4 0.028
nuclear transport GO:0051169 139 0.028
regulation of canonical wnt signaling pathway GO:0060828 82 0.028
negative regulation of cellular amine metabolic process GO:0033239 1 0.028
heart contraction GO:0060047 93 0.027
positive regulation of smooth muscle cell migration GO:0014911 4 0.027
gtp metabolic process GO:0046039 144 0.027
circadian rhythm GO:0007623 114 0.027
development of primary male sexual characteristics GO:0046546 88 0.027
telencephalon development GO:0021537 186 0.027
lipid localization GO:0010876 126 0.027
regulation of protein processing GO:0070613 96 0.027
learning or memory GO:0007611 148 0.027
Rat
guanosine containing compound catabolic process GO:1901069 144 0.027
regulation of hormone secretion GO:0046883 88 0.027
Rat
blood vessel endothelial cell migration GO:0043534 23 0.027
response to oxidative stress GO:0006979 123 0.026
regulation of erk1 and erk2 cascade GO:0070372 71 0.026
immune response activating signal transduction GO:0002757 116 0.026
regulation of protein targeting GO:1903533 61 0.026
regulation of vesicle mediated transport GO:0060627 139 0.026
regulation of lymphocyte differentiation GO:0045619 107 0.026
water transport GO:0006833 12 0.026
negative regulation of map kinase activity GO:0043407 34 0.026
hepaticobiliary system development GO:0061008 67 0.026
regulation of neuron projection development GO:0010975 169 0.026
myeloid cell homeostasis GO:0002262 114 0.026
cellular response to acid chemical GO:0071229 68 0.026
regulation of rho gtpase activity GO:0032319 58 0.026
innate immune response GO:0045087 157 0.025
regulation of cytoplasmic transport GO:1903649 112 0.025
regulation of nucleotide catabolic process GO:0030811 122 0.025
cellular biogenic amine metabolic process GO:0006576 28 0.025
regulation of protein complex disassembly GO:0043244 28 0.025
cellular response to organonitrogen compound GO:0071417 145 0.025
response to steroid hormone GO:0048545 56 0.025
Rat
response to corticosterone GO:0051412 1 0.025
Rat
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.025
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.025
cellular macromolecule catabolic process GO:0044265 206 0.025
regulation of proteolysis GO:0030162 164 0.025
regulation of glial cell differentiation GO:0045685 41 0.025
response to ionizing radiation GO:0010212 42 0.025
renal tubule morphogenesis GO:0061333 72 0.025
response to transition metal nanoparticle GO:1990267 11 0.025
negative regulation of transferase activity GO:0051348 85 0.025
single organism nuclear import GO:1902593 95 0.025
calcium ion homeostasis GO:0055074 127 0.025
positive regulation of nervous system development GO:0051962 221 0.025
myeloid leukocyte differentiation GO:0002573 119 0.024
cellular response to organic cyclic compound GO:0071407 87 0.024
Zebrafish
protein catabolic process GO:0030163 221 0.024
regulation of cellular catabolic process GO:0031329 242 0.024
ameboidal type cell migration GO:0001667 128 0.024
response to purine containing compound GO:0014074 28 0.024
regulation of protein import into nucleus GO:0042306 52 0.024
nucleoside triphosphate catabolic process GO:0009143 205 0.024
hormone secretion GO:0046879 128 0.024
Rat
cellular response to inorganic substance GO:0071241 37 0.024
regulation of nucleoside metabolic process GO:0009118 130 0.024
fever generation GO:0001660 7 0.024
Mouse
regulation of peptide transport GO:0090087 91 0.024
membrane lipid metabolic process GO:0006643 53 0.024
epithelial cell development GO:0002064 159 0.024
regulation of wound healing GO:0061041 40 0.024
negative regulation of cell growth GO:0030308 44 0.024
cell activation involved in immune response GO:0002263 126 0.024
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 9 0.024
cell type specific apoptotic process GO:0097285 268 0.024
response to radiation GO:0009314 165 0.023
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.023
regulation of cell shape GO:0008360 39 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
activation of mapk activity GO:0000187 59 0.023
regulation of ras protein signal transduction GO:0046578 114 0.023
cell growth GO:0016049 130 0.023
gtp catabolic process GO:0006184 143 0.023
placenta development GO:0001890 140 0.023
Mouse
regulation of neuron differentiation GO:0045664 281 0.023
leukocyte homeostasis GO:0001776 79 0.023
neuron apoptotic process GO:0051402 142 0.023
regulation of chemokine production GO:0032642 30 0.023
response to vitamin d GO:0033280 3 0.023
striated muscle contraction GO:0006941 45 0.023
glycerophospholipid metabolic process GO:0006650 71 0.023
regulation of systemic arterial blood pressure GO:0003073 61 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.022
regulation of calcium ion transport GO:0051924 69 0.022
response to organophosphorus GO:0046683 22 0.022
negative regulation of cell migration GO:0030336 59 0.022
cell growth involved in cardiac muscle cell development GO:0061049 3 0.022
sphingolipid metabolic process GO:0006665 45 0.022

Ptgs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.077
disease of anatomical entity DOID:7 0 0.077
hematopoietic system disease DOID:74 0 0.077
disease of metabolism DOID:0014667 0 0.034
inherited metabolic disorder DOID:655 0 0.034
nervous system disease DOID:863 0 0.031
musculoskeletal system disease DOID:17 0 0.030
connective tissue disease DOID:65 0 0.030
sensory system disease DOID:0050155 0 0.026