Mus musculus

22 known processes

Fhit

fragile histidine triad gene

(Aliases: AW045638,Fra14A2)

Fhit biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 44 0.070
cellular amino acid metabolic process GO:0006520 103 0.065
regulation of cellular amine metabolic process GO:0033238 20 0.061
positive regulation of cellular amine metabolic process GO:0033240 5 0.055
oxidation reduction process GO:0055114 342 0.055
regulation of ion transport GO:0043269 215 0.054
cellular ketone metabolic process GO:0042180 84 0.054
regulation of hormone levels GO:0010817 211 0.053
nucleobase containing small molecule metabolic process GO:0055086 352 0.051
regulation of membrane potential GO:0042391 192 0.049
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
transmembrane transport GO:0055085 412 0.046
organic cyclic compound catabolic process GO:1901361 295 0.046
amine metabolic process GO:0009308 45 0.044
nucleotide metabolic process GO:0009117 332 0.043
cellular nitrogen compound catabolic process GO:0044270 280 0.041
muscle contraction GO:0006936 101 0.040
sensory organ morphogenesis GO:0090596 242 0.039
nucleoside phosphate metabolic process GO:0006753 338 0.039
nitrogen compound transport GO:0071705 271 0.038
dna metabolic process GO:0006259 303 0.038
regulation of cellular amino acid metabolic process GO:0006521 5 0.037
regulation of body fluid levels GO:0050878 162 0.037
blood circulation GO:0008015 195 0.036
sensory perception GO:0007600 245 0.036
positive regulation of cell death GO:0010942 224 0.035
cation transport GO:0006812 399 0.035
aromatic compound catabolic process GO:0019439 286 0.035
purine ribonucleotide metabolic process GO:0009150 290 0.035
small molecule biosynthetic process GO:0044283 132 0.035
muscle system process GO:0003012 141 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.035
regulation of secretion GO:0051046 274 0.034
purine containing compound metabolic process GO:0072521 311 0.034
heterocycle catabolic process GO:0046700 280 0.034
male gamete generation GO:0048232 285 0.032
circulatory system process GO:0003013 197 0.032
embryonic organ morphogenesis GO:0048562 276 0.031
ribose phosphate metabolic process GO:0019693 291 0.030
organelle assembly GO:0070925 177 0.030
regulation of secretion by cell GO:1903530 249 0.030
macromolecule catabolic process GO:0009057 281 0.030
regulation of system process GO:0044057 200 0.029
cellular amide metabolic process GO:0043603 58 0.029
purine nucleotide metabolic process GO:0006163 302 0.029
neuronal action potential GO:0019228 54 0.029
nucleoside metabolic process GO:0009116 246 0.028
cofactor metabolic process GO:0051186 80 0.028
ribonucleotide metabolic process GO:0009259 291 0.028
organic hydroxy compound transport GO:0015850 93 0.028
organonitrogen compound biosynthetic process GO:1901566 192 0.027
organic hydroxy compound metabolic process GO:1901615 203 0.027
developmental maturation GO:0021700 193 0.027
glutathione metabolic process GO:0006749 16 0.027
regulation of cellular catabolic process GO:0031329 242 0.027
skeletal system development GO:0001501 356 0.027
camera type eye development GO:0043010 266 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
actin cytoskeleton organization GO:0030036 220 0.026
sulfur compound metabolic process GO:0006790 100 0.026
alpha amino acid metabolic process GO:1901605 59 0.026
glycosyl compound metabolic process GO:1901657 246 0.025
carbohydrate metabolic process GO:0005975 230 0.025
response to organonitrogen compound GO:0010243 246 0.025
organic acid biosynthetic process GO:0016053 86 0.025
ion transmembrane transport GO:0034220 361 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
striated muscle tissue development GO:0014706 293 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
lipid biosynthetic process GO:0008610 179 0.024
transmission of nerve impulse GO:0019226 76 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
organonitrogen compound catabolic process GO:1901565 264 0.023
protein maturation GO:0051604 176 0.023
positive regulation of programmed cell death GO:0043068 218 0.023
cellular lipid metabolic process GO:0044255 323 0.023
positive regulation of apoptotic process GO:0043065 217 0.023
membrane organization GO:0061024 245 0.023
cellular homeostasis GO:0019725 240 0.022
action potential GO:0001508 78 0.022
cellular carbohydrate metabolic process GO:0044262 119 0.022
synaptic transmission GO:0007268 329 0.022
renal system development GO:0072001 225 0.022
protein processing GO:0016485 163 0.022
response to acid chemical GO:0001101 111 0.022
muscle cell differentiation GO:0042692 261 0.022
metal ion homeostasis GO:0055065 189 0.022
peptide transport GO:0015833 133 0.022
response to inorganic substance GO:0010035 96 0.022
anion transport GO:0006820 177 0.022
carboxylic acid biosynthetic process GO:0046394 86 0.022
regulation of protein kinase activity GO:0045859 232 0.021
positive regulation of protein modification process GO:0031401 299 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
gland development GO:0048732 330 0.021
mitochondrion organization GO:0007005 134 0.021
hormone metabolic process GO:0042445 86 0.021
cell type specific apoptotic process GO:0097285 268 0.021
multicellular organismal signaling GO:0035637 91 0.021
regulation of organelle organization GO:0033043 289 0.021
regulation of hydrolase activity GO:0051336 246 0.021
ribonucleoside metabolic process GO:0009119 245 0.021
leukocyte differentiation GO:0002521 342 0.020
spermatogenesis GO:0007283 284 0.020
muscle tissue development GO:0060537 308 0.020
monocarboxylic acid metabolic process GO:0032787 191 0.020
organelle fission GO:0048285 170 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.019
heart process GO:0003015 94 0.019
cation homeostasis GO:0055080 212 0.019
g protein coupled receptor signaling pathway GO:0007186 243 0.019
regulation of action potential GO:0098900 4 0.019
regulation of protein localization GO:0032880 231 0.019
alcohol metabolic process GO:0006066 116 0.019
connective tissue development GO:0061448 179 0.019
amide transport GO:0042886 138 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
intracellular protein transport GO:0006886 204 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
cation transmembrane transport GO:0098655 266 0.018
ras protein signal transduction GO:0007265 77 0.018
organophosphate catabolic process GO:0046434 232 0.018
placenta development GO:0001890 140 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
digestive tract development GO:0048565 190 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
cellular chemical homeostasis GO:0055082 215 0.018
apoptotic signaling pathway GO:0097190 306 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
retina development in camera type eye GO:0060041 119 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
carbohydrate homeostasis GO:0033500 128 0.017
regulation of cell motility GO:2000145 236 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
multi multicellular organism process GO:0044706 109 0.017
cardiac muscle tissue development GO:0048738 130 0.017
peptide secretion GO:0002790 114 0.017
rho protein signal transduction GO:0007266 32 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
striated muscle contraction GO:0006941 45 0.017
cellular modified amino acid metabolic process GO:0006575 63 0.017
cellular metal ion homeostasis GO:0006875 151 0.017
regulation of cell activation GO:0050865 289 0.017
striated muscle cell development GO:0055002 125 0.017
methylation GO:0032259 134 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
telencephalon development GO:0021537 186 0.017
ossification GO:0001503 216 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.017
organic anion transport GO:0015711 137 0.016
monosaccharide metabolic process GO:0005996 106 0.016
regulation of muscle system process GO:0090257 80 0.016
blood vessel morphogenesis GO:0048514 285 0.016
cellular ion homeostasis GO:0006873 165 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
protein catabolic process GO:0030163 221 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
cell maturation GO:0048469 127 0.016
myeloid cell differentiation GO:0030099 233 0.016
mapk cascade GO:0000165 281 0.016
nuclear division GO:0000280 158 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
positive regulation of nervous system development GO:0051962 221 0.016
steroid metabolic process GO:0008202 119 0.016
locomotory behavior GO:0007626 195 0.016
peptide hormone secretion GO:0030072 109 0.016
carbohydrate biosynthetic process GO:0016051 74 0.016
cellular response to dna damage stimulus GO:0006974 207 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.015
peptide metabolic process GO:0006518 46 0.015
nucleoside catabolic process GO:0009164 206 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
regulation of neuron differentiation GO:0045664 281 0.015
heart contraction GO:0060047 93 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
sensory perception of mechanical stimulus GO:0050954 107 0.015
skin development GO:0043588 220 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
positive regulation of cell development GO:0010720 237 0.015
regulation of protein transport GO:0051223 163 0.015
wound healing GO:0042060 157 0.015
regulation of cell projection organization GO:0031344 206 0.015
regulation of transferase activity GO:0051338 263 0.015
retinoic acid metabolic process GO:0042573 12 0.015
regulation of blood circulation GO:1903522 93 0.015
cellular component assembly involved in morphogenesis GO:0010927 139 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
negative regulation of cell development GO:0010721 169 0.015
respiratory system development GO:0060541 190 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
response to extracellular stimulus GO:0009991 127 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
response to peptide hormone GO:0043434 127 0.014
regulation of transmembrane transport GO:0034762 128 0.014
germ cell development GO:0007281 185 0.014
positive regulation of transferase activity GO:0051347 167 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
fatty acid metabolic process GO:0006631 121 0.014
ear development GO:0043583 200 0.014
cellular alcohol metabolic process GO:0044107 3 0.014
homeostasis of number of cells GO:0048872 210 0.014
generation of precursor metabolites and energy GO:0006091 103 0.014
regulation of cell cycle GO:0051726 281 0.014
cell junction organization GO:0034330 77 0.014
cellular response to lipid GO:0071396 145 0.014
energy derivation by oxidation of organic compounds GO:0015980 77 0.014
positive regulation of secretion GO:0051047 130 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
urogenital system development GO:0001655 261 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
response to organic cyclic compound GO:0014070 198 0.013
cardiac muscle contraction GO:0060048 32 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.013
coenzyme metabolic process GO:0006732 52 0.013
cell adhesion GO:0007155 329 0.013
cytokine production GO:0001816 319 0.013
forebrain development GO:0030900 302 0.013
positive regulation of kinase activity GO:0033674 155 0.013
hexose metabolic process GO:0019318 98 0.013
cellular protein complex assembly GO:0043623 116 0.013
response to light stimulus GO:0009416 135 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
epithelial cell development GO:0002064 159 0.013
amino acid transmembrane transport GO:0003333 37 0.013
positive regulation of secretion by cell GO:1903532 114 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
detection of stimulus GO:0051606 84 0.013
regulation of neuron death GO:1901214 134 0.013
regulation of renal sodium excretion GO:0035813 3 0.013
dephosphorylation GO:0016311 129 0.013
muscle cell development GO:0055001 133 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
regulation of kinase activity GO:0043549 249 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
tissue homeostasis GO:0001894 115 0.013
lipoprotein metabolic process GO:0042157 43 0.013
regulation of multi organism process GO:0043900 111 0.013
hormone secretion GO:0046879 128 0.013
calcium ion homeostasis GO:0055074 127 0.013
ventricular cardiac muscle cell action potential GO:0086005 4 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
fertilization GO:0009566 127 0.012
interleukin 8 production GO:0032637 4 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
response to hypoxia GO:0001666 58 0.012
response to nutrient levels GO:0031667 109 0.012
negative regulation of molecular function GO:0044092 258 0.012
catecholamine uptake GO:0090493 4 0.012
myelination GO:0042552 74 0.012
response to radiation GO:0009314 165 0.012
protein localization to organelle GO:0033365 185 0.012
organic acid transport GO:0015849 101 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
response to peptide GO:1901652 136 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
lymphocyte differentiation GO:0030098 242 0.012
positive regulation of plasminogen activation GO:0010756 2 0.012
regulation of mapk cascade GO:0043408 248 0.012
glucose metabolic process GO:0006006 92 0.012
protein targeting GO:0006605 143 0.012
heart morphogenesis GO:0003007 178 0.012
ensheathment of neurons GO:0007272 76 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
midgut development GO:0007494 4 0.012
axon ensheathment GO:0008366 76 0.012
purine containing compound catabolic process GO:0072523 213 0.012
atp metabolic process GO:0046034 75 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
monosaccharide transport GO:0015749 58 0.011
regulation of peptide secretion GO:0002791 77 0.011
cytoplasmic transport GO:0016482 234 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
positive regulation of fatty acid oxidation GO:0046321 4 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.011
small molecule catabolic process GO:0044282 71 0.011
regulation of protein maturation GO:1903317 96 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
circadian rhythm GO:0007623 114 0.011
carbohydrate transport GO:0008643 62 0.011
negative regulation of cell cycle GO:0045786 123 0.011
cellular response to acid chemical GO:0071229 68 0.011
rhythmic process GO:0048511 174 0.011
negative regulation of protein metabolic process GO:0051248 282 0.011
regulation of proteolysis GO:0030162 164 0.011
chemotaxis GO:0006935 247 0.011
sensory system development GO:0048880 3 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
renal sodium excretion GO:0035812 3 0.011
sperm motility GO:0030317 47 0.011
interleukin 8 secretion GO:0072606 3 0.011
folic acid containing compound metabolic process GO:0006760 3 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
epithelial cell proliferation GO:0050673 174 0.011
striated muscle myosin thick filament assembly GO:0071688 1 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
regulation of peptide transport GO:0090087 91 0.011
regulation of fat cell differentiation GO:0045598 81 0.011
regulation of blood pressure GO:0008217 93 0.011
myosin filament organization GO:0031033 3 0.011
microtubule based process GO:0007017 236 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.011
nucleotide catabolic process GO:0009166 217 0.011
cell fate commitment GO:0045165 210 0.011
glucose homeostasis GO:0042593 128 0.011
regulation of peptide hormone secretion GO:0090276 75 0.011
inflammatory response GO:0006954 244 0.011
adult behavior GO:0030534 135 0.011
regulation of carbohydrate metabolic process GO:0006109 75 0.011
anatomical structure homeostasis GO:0060249 145 0.011
regulation of cytokine production GO:0001817 266 0.011
body fluid secretion GO:0007589 53 0.011
gtp catabolic process GO:0006184 143 0.010
cofactor transport GO:0051181 4 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
regulation of interleukin 8 production GO:0032677 3 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
protein secretion GO:0009306 111 0.010
monocarboxylic acid biosynthetic process GO:0072330 61 0.010
reactive oxygen species metabolic process GO:0072593 84 0.010
regulation of metal ion transport GO:0010959 106 0.010
nucleoside phosphate biosynthetic process GO:1901293 79 0.010
modification dependent protein catabolic process GO:0019941 133 0.010
endocytosis GO:0006897 168 0.010
spermatid differentiation GO:0048515 115 0.010
immune effector process GO:0002252 321 0.010
regulation of homeostatic process GO:0032844 182 0.010
bone development GO:0060348 120 0.010
digestive system development GO:0055123 200 0.010
ammonia assimilation cycle GO:0019676 2 0.010
activation of adenylate cyclase activity GO:0007190 4 0.010
regulation of plasminogen activation GO:0010755 4 0.010
inorganic ion transmembrane transport GO:0098660 234 0.010
meiotic cell cycle GO:0051321 122 0.010
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
respiratory tube development GO:0030323 167 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010

Fhit disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.023
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
disease of metabolism DOID:0014667 0 0.017
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
neurodegenerative disease DOID:1289 0 0.014
inherited metabolic disorder DOID:655 0 0.013
thoracic cancer DOID:5093 0 0.011