Mus musculus

79 known processes

Pax4

paired box gene 4

(Aliases: Pax-4)

Pax4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amino acid metabolic process GO:0006521 5 0.295
carbohydrate derivative biosynthetic process GO:1901137 183 0.252
cytokine production GO:0001816 319 0.221
regulation of blood pressure GO:0008217 93 0.190
regulation of cellular amine metabolic process GO:0033238 20 0.188
regulation of cytokine production GO:0001817 266 0.184
muscle system process GO:0003012 141 0.177
regulation of systemic arterial blood pressure GO:0003073 61 0.164
amine metabolic process GO:0009308 45 0.162
somatostatin signaling pathway GO:0038170 2 0.154
cellular ketone metabolic process GO:0042180 84 0.150
glycoprotein metabolic process GO:0009100 116 0.145
positive regulation of mapk cascade GO:0043410 170 0.137
peptidyl amino acid modification GO:0018193 336 0.136
cellular ion homeostasis GO:0006873 165 0.134
regulation of transferase activity GO:0051338 263 0.133
regulation of secretion GO:0051046 274 0.132
regulation of protein transport GO:0051223 163 0.130
negative regulation of interleukin 5 secretion GO:2000663 1 0.123
nucleoside phosphate biosynthetic process GO:1901293 79 0.123
cellular amine metabolic process GO:0044106 44 0.119
nucleotide biosynthetic process GO:0009165 78 0.119
ion transmembrane transport GO:0034220 361 0.119
regulation of establishment of protein localization GO:0070201 181 0.117
nucleobase containing small molecule metabolic process GO:0055086 352 0.116
positive regulation of protein phosphorylation GO:0001934 242 0.113
positive regulation of apoptotic process GO:0043065 217 0.113
regulation of purine nucleotide metabolic process GO:1900542 169 0.113
organonitrogen compound biosynthetic process GO:1901566 192 0.112
purine nucleotide metabolic process GO:0006163 302 0.110
negative regulation of cell proliferation GO:0008285 296 0.107
Mouse
cation transport GO:0006812 399 0.103
regulation of saliva secretion GO:0046877 2 0.102
positive regulation of programmed cell death GO:0043068 218 0.101
purine containing compound metabolic process GO:0072521 311 0.096
interleukin 13 secretion GO:0072611 2 0.091
acid secretion GO:0046717 33 0.090
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.085
regulation of nucleotide metabolic process GO:0006140 169 0.085
cyclic nucleotide metabolic process GO:0009187 59 0.083
peptidyl tyrosine modification GO:0018212 145 0.080
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.078
macromolecule catabolic process GO:0009057 281 0.077
ribose phosphate biosynthetic process GO:0046390 59 0.074
negative regulation of interleukin 13 secretion GO:2000666 1 0.074
positive regulation of protein modification process GO:0031401 299 0.073
negative regulation of immune system process GO:0002683 209 0.072
ossification GO:0001503 216 0.069
cytoplasmic transport GO:0016482 234 0.067
regulation of smooth muscle contraction GO:0006940 22 0.066
purine ribonucleotide metabolic process GO:0009150 290 0.066
transmembrane transport GO:0055085 412 0.065
positive regulation of protein secretion GO:0050714 52 0.065
astrocyte fate commitment GO:0060018 4 0.064
cellular amino acid metabolic process GO:0006520 103 0.063
metal ion homeostasis GO:0055065 189 0.063
forebrain development GO:0030900 302 0.062
Mouse
negative regulation of interleukin 13 production GO:0032696 2 0.062
cellular macromolecule catabolic process GO:0044265 206 0.061
lung development GO:0030324 164 0.060
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.060
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.060
regulation of camp metabolic process GO:0030814 30 0.059
organophosphate biosynthetic process GO:0090407 122 0.059
divalent inorganic cation transport GO:0072511 178 0.058
purine ribonucleotide biosynthetic process GO:0009152 59 0.058
regulation of cytokine secretion GO:0050707 61 0.058
regulation of apoptotic signaling pathway GO:2001233 197 0.057
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.057
lymphocyte activation involved in immune response GO:0002285 93 0.057
ribonucleotide metabolic process GO:0009259 291 0.056
protein secretion GO:0009306 111 0.056
somatotropin secreting cell differentiation GO:0060126 4 0.056
regulation of secretion by cell GO:1903530 249 0.056
g protein coupled receptor signaling pathway GO:0007186 243 0.056
ribose phosphate metabolic process GO:0019693 291 0.056
regulation of ion transport GO:0043269 215 0.055
epithelial tube morphogenesis GO:0060562 303 0.055
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.054
nucleotide metabolic process GO:0009117 332 0.054
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.053
protein catabolic process GO:0030163 221 0.052
regulation of protein secretion GO:0050708 82 0.050
regulation of metal ion transport GO:0010959 106 0.050
positive regulation of homeostatic process GO:0032846 64 0.049
cell fate commitment GO:0045165 210 0.049
Mouse
regulation of cellular catabolic process GO:0031329 242 0.049
heart morphogenesis GO:0003007 178 0.048
regulation of blood vessel size GO:0050880 56 0.048
regulation of interleukin 13 secretion GO:2000665 2 0.048
protein localization to organelle GO:0033365 185 0.048
Mouse
regulation of ossification GO:0030278 112 0.048
positive regulation of protein kinase activity GO:0045860 144 0.047
cellular chemical homeostasis GO:0055082 215 0.047
inorganic cation transmembrane transport GO:0098662 207 0.047
somatostatin receptor signaling pathway GO:0038169 2 0.047
positive regulation of protein transport GO:0051222 93 0.047
organic hydroxy compound metabolic process GO:1901615 203 0.046
cell activation involved in immune response GO:0002263 126 0.046
regulation of kinase activity GO:0043549 249 0.046
positive regulation of ossification GO:0045778 47 0.045
smooth muscle contraction GO:0006939 44 0.045
negative regulation of t cell cytokine production GO:0002725 1 0.045
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.044
cellular protein catabolic process GO:0044257 155 0.044
regulation of cellular ketone metabolic process GO:0010565 66 0.044
regulation of protein localization GO:0032880 231 0.044
calcium ion transmembrane transport GO:0070588 85 0.043
fertilization GO:0009566 127 0.043
fat cell differentiation GO:0045444 160 0.043
nuclear transport GO:0051169 139 0.043
dopamine uptake involved in synaptic transmission GO:0051583 4 0.043
purine containing compound biosynthetic process GO:0072522 70 0.042
regulation of cell cycle GO:0051726 281 0.042
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 18 0.042
cellular homeostasis GO:0019725 240 0.042
angiogenesis GO:0001525 201 0.041
reactive oxygen species metabolic process GO:0072593 84 0.041
purine nucleotide biosynthetic process GO:0006164 65 0.040
camp metabolic process GO:0046058 40 0.040
negative regulation of defense response GO:0031348 77 0.040
response to light stimulus GO:0009416 135 0.038
cyclic nucleotide biosynthetic process GO:0009190 44 0.038
cytokine secretion GO:0050663 72 0.038
lymphocyte differentiation GO:0030098 242 0.038
protein ubiquitination GO:0016567 171 0.038
positive regulation of cellular amine metabolic process GO:0033240 5 0.038
regulation of renal sodium excretion GO:0035813 3 0.038
protein modification by small protein conjugation or removal GO:0070647 207 0.038
habituation GO:0046959 3 0.037
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 3 0.037
ameboidal type cell migration GO:0001667 128 0.037
regulation of mapk cascade GO:0043408 248 0.036
forebrain morphogenesis GO:0048853 17 0.035
negative regulation of stem cell maintenance GO:1902455 4 0.035
regulation of muscle system process GO:0090257 80 0.035
feeding behavior GO:0007631 62 0.035
negative regulation of epithelial cell proliferation GO:0050680 64 0.035
Mouse
embryonic organ morphogenesis GO:0048562 276 0.034
Mouse
positive regulation of secretion GO:0051047 130 0.034
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.034
regulation of tube size GO:0035150 57 0.034
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.033
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.033
respiratory tube development GO:0030323 167 0.033
regulation of cell division GO:0051302 76 0.033
Mouse
regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback GO:0001978 5 0.033
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.033
camera type eye development GO:0043010 266 0.032
Mouse Rat
response to extracellular stimulus GO:0009991 127 0.032
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.032
negative regulation of blood pressure GO:0045776 22 0.032
regulation of multi organism process GO:0043900 111 0.032
b cell activation GO:0042113 161 0.032
apoptotic signaling pathway GO:0097190 306 0.032
cellular calcium ion homeostasis GO:0006874 119 0.032
respiratory system development GO:0060541 190 0.031
purine ribonucleoside catabolic process GO:0046130 205 0.031
blood circulation GO:0008015 195 0.031
ribonucleotide biosynthetic process GO:0009260 59 0.031
positive regulation of cell death GO:0010942 224 0.031
cellular potassium ion transport GO:0071804 43 0.030
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.030
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.030
regulation of muscle tissue development GO:1901861 97 0.030
glial cell differentiation GO:0010001 131 0.030
Mouse
protein localization to membrane GO:0072657 108 0.030
cation homeostasis GO:0055080 212 0.030
myeloid cell differentiation GO:0030099 233 0.030
neuroepithelial cell differentiation GO:0060563 37 0.030
divalent inorganic cation homeostasis GO:0072507 138 0.030
negative regulation of cellular protein metabolic process GO:0032269 247 0.029
Mouse
limb development GO:0060173 166 0.029
positive regulation of transferase activity GO:0051347 167 0.029
positive regulation of cytokine secretion GO:0050715 41 0.029
positive regulation of cellular catabolic process GO:0031331 148 0.029
positive regulation of epithelial cell proliferation GO:0050679 68 0.029
cellular metal ion homeostasis GO:0006875 151 0.029
establishment of protein localization to organelle GO:0072594 118 0.028
hypophysis morphogenesis GO:0048850 3 0.028
t cell differentiation GO:0030217 174 0.028
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.028
negative regulation of cytokine production GO:0001818 84 0.028
specification of organ identity GO:0010092 30 0.028
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.028
regulation of ketone biosynthetic process GO:0010566 2 0.028
negative regulation of cell development GO:0010721 169 0.028
Mouse
regulation of circadian sleep wake cycle GO:0042749 3 0.028
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.028
glycoprotein biosynthetic process GO:0009101 89 0.028
nucleoside phosphate metabolic process GO:0006753 338 0.028
protein localization to nucleus GO:0034504 121 0.027
negative regulation of prostatic bud formation GO:0060686 4 0.027
natural killer cell activation involved in immune response GO:0002323 10 0.027
leukocyte activation involved in immune response GO:0002366 126 0.027
ear development GO:0043583 200 0.027
endomembrane system organization GO:0010256 147 0.027
divalent metal ion transport GO:0070838 172 0.027
modification dependent protein catabolic process GO:0019941 133 0.027
interleukin 5 secretion GO:0072603 2 0.026
negative regulation of secretion by cell GO:1903531 54 0.026
meiotic nuclear division GO:0007126 115 0.026
positive regulation of kinase activity GO:0033674 155 0.026
signal transduction by p53 class mediator GO:0072331 51 0.026
negative regulation of leukocyte differentiation GO:1902106 51 0.026
leukocyte differentiation GO:0002521 342 0.026
response to transforming growth factor beta GO:0071559 88 0.026
response to lipopolysaccharide GO:0032496 128 0.026
regulation of epithelial cell proliferation GO:0050678 141 0.026
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.026
cyclic purine nucleotide metabolic process GO:0052652 43 0.026
multicellular organismal homeostasis GO:0048871 164 0.026
positive regulation of ion transport GO:0043270 65 0.026
negative regulation of cell activation GO:0050866 111 0.025
regulation of interleukin 5 secretion GO:2000662 2 0.025
response to oxidative stress GO:0006979 123 0.025
renal sodium excretion GO:0035812 3 0.025
cellular response to growth factor stimulus GO:0071363 197 0.025
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.025
renal tubule morphogenesis GO:0061333 72 0.025
t cell mediated immunity GO:0002456 50 0.025
neuron death GO:0070997 154 0.025
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.025
protein modification by small protein conjugation GO:0032446 187 0.024
epithelial cell development GO:0002064 159 0.024
Mouse
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.024
multicellular organismal response to stress GO:0033555 62 0.024
baroreceptor response to decreased systemic arterial blood pressure GO:0001982 2 0.024
positive regulation of high voltage gated calcium channel activity GO:1901843 1 0.024
negative regulation of cellular amine metabolic process GO:0033239 1 0.024
positive regulation of transcription via serum response element binding GO:0010735 1 0.024
single fertilization GO:0007338 82 0.024
cytosolic calcium ion homeostasis GO:0051480 70 0.024
response to acid chemical GO:0001101 111 0.024
immune effector process GO:0002252 321 0.024
response to growth factor GO:0070848 198 0.024
smoothened signaling pathway GO:0007224 105 0.024
Mouse
epithelial cell migration GO:0010631 63 0.024
intracellular protein transport GO:0006886 204 0.023
negative regulation of secretion GO:0051048 61 0.023
muscle contraction GO:0006936 101 0.023
regulation of protein kinase activity GO:0045859 232 0.023
positive regulation of amino acid transport GO:0051957 4 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
Mouse
neuronal action potential GO:0019228 54 0.023
negative regulation of viral entry into host cell GO:0046597 10 0.023
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.023
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.023
germ cell development GO:0007281 185 0.023
sperm egg recognition GO:0035036 37 0.022
entry into host GO:0044409 15 0.022
memory GO:0007613 58 0.022
cardiac chamber development GO:0003205 108 0.022
calcium mediated signaling GO:0019722 46 0.022
paramesonephric duct development GO:0061205 3 0.022
regulation of circadian rhythm GO:0042752 58 0.022
dopamine receptor signaling pathway GO:0007212 16 0.022
nucleoside metabolic process GO:0009116 246 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
positive regulation of osteoblast differentiation GO:0045669 34 0.022
t cell activation GO:0042110 289 0.022
positive regulation of map kinase activity GO:0043406 84 0.022
male sex determination GO:0030238 14 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
regulation of heart growth GO:0060420 31 0.021
central nervous system neuron differentiation GO:0021953 162 0.021
Mouse
binding of sperm to zona pellucida GO:0007339 34 0.021
renal vesicle induction GO:0072034 3 0.021
regulation of nucleotide biosynthetic process GO:0030808 34 0.020
negative regulation of molecular function GO:0044092 258 0.020
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.020
circulatory system process GO:0003013 197 0.020
digestion GO:0007586 40 0.020
protein import GO:0017038 101 0.020
regulation of camp biosynthetic process GO:0030817 25 0.020
carbohydrate metabolic process GO:0005975 230 0.020
synapse organization GO:0050808 125 0.020
positive regulation of leukocyte proliferation GO:0070665 73 0.020
positive regulation of secretion by cell GO:1903532 114 0.020
second messenger mediated signaling GO:0019932 73 0.020
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.020
positive regulation of gtp catabolic process GO:0033126 85 0.020
kidney morphogenesis GO:0060993 83 0.020
circadian sleep wake cycle rem sleep GO:0042747 1 0.020
female genitalia morphogenesis GO:0048807 3 0.020
defense response to bacterium GO:0042742 119 0.020
regulation of cell cycle process GO:0010564 160 0.020
rhythmic process GO:0048511 174 0.020
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.020
neuron apoptotic process GO:0051402 142 0.019
lung alveolus development GO:0048286 45 0.019
digestive system development GO:0055123 200 0.019
blastocyst development GO:0001824 80 0.019
positive regulation of purine nucleotide biosynthetic process GO:1900373 26 0.019
regulation of cellular response to stress GO:0080135 159 0.019
multicellular organism growth GO:0035264 161 0.019
positive regulation of neuron differentiation GO:0045666 141 0.019
astrocyte differentiation GO:0048708 43 0.019
Mouse
cell cell recognition GO:0009988 44 0.019
transition metal ion homeostasis GO:0055076 54 0.019
positive regulation of nucleotide metabolic process GO:0045981 114 0.019
midgut development GO:0007494 4 0.019
organelle fission GO:0048285 170 0.019
circadian rhythm GO:0007623 114 0.019
Rat
isoprenoid metabolic process GO:0006720 29 0.019
mapk cascade GO:0000165 281 0.019
sensory perception of pain GO:0019233 47 0.019
negative regulation of keratinocyte differentiation GO:0045617 4 0.019
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.019
oxidation reduction process GO:0055114 342 0.019
potassium ion transport GO:0006813 52 0.019
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.019
heart growth GO:0060419 45 0.018
pancreatic a cell fate commitment GO:0003326 2 0.018
cellular lipid metabolic process GO:0044255 323 0.018
calcium ion homeostasis GO:0055074 127 0.018
atrioventricular node cell development GO:0060928 2 0.018
prostate gland development GO:0030850 48 0.018
wnt signaling pathway GO:0016055 188 0.018
branching morphogenesis of an epithelial tube GO:0048754 159 0.018
positive regulation of glutamate secretion GO:0014049 2 0.018
otic placode formation GO:0043049 1 0.018
purkinje myocyte differentiation GO:0003168 1 0.018
notch signaling pathway GO:0007219 71 0.018
viral gene expression GO:0019080 3 0.018
stem cell development GO:0048864 219 0.018
b cell differentiation GO:0030183 78 0.018
nuclear division GO:0000280 158 0.018
vascular process in circulatory system GO:0003018 62 0.018
multicellular organismal metabolic process GO:0044236 28 0.018
regulation of production of molecular mediator of immune response GO:0002700 65 0.018
leukocyte mediated immunity GO:0002443 174 0.018
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.018
Mouse
protein acylation GO:0043543 64 0.017
regulation of stem cell maintenance GO:2000036 17 0.017
skeletal system morphogenesis GO:0048705 203 0.017
negative regulation of serotonin secretion GO:0014063 2 0.017
homeostasis of number of cells GO:0048872 210 0.017
negative regulation of cell cycle GO:0045786 123 0.017
cardiac pacemaker cell fate commitment GO:0060927 1 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
regulation of system process GO:0044057 200 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.017
vitamin a metabolic process GO:0006776 2 0.017
bronchiole morphogenesis GO:0060436 1 0.017
response to oxygen levels GO:0070482 62 0.017
sensory perception GO:0007600 245 0.017
positive regulation of vasoconstriction GO:0045907 4 0.017
regulation of nucleoside metabolic process GO:0009118 130 0.017
atrioventricular node cell fate commitment GO:0060929 1 0.017
protein targeting GO:0006605 143 0.017
potassium ion transmembrane transport GO:0071805 43 0.017
proteasomal protein catabolic process GO:0010498 98 0.017
cell cycle arrest GO:0007050 37 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
regulation of anatomical structure size GO:0090066 178 0.017
regulation of interleukin 8 secretion GO:2000482 2 0.017
leukocyte migration GO:0050900 124 0.017
regulation of defense response GO:0031347 233 0.017
semicircular canal fusion GO:0060879 1 0.017
generation of ovulation cycle rhythm GO:0060112 1 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.016
Mouse
regulation of neuron death GO:1901214 134 0.016
regulation of cardiac muscle tissue development GO:0055024 31 0.016
bone development GO:0060348 120 0.016
ureter morphogenesis GO:0072197 4 0.016
regulation of isoprenoid metabolic process GO:0019747 1 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
striated muscle tissue development GO:0014706 293 0.016
learning or memory GO:0007611 148 0.016
defense response to virus GO:0051607 68 0.016
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.016
response to nutrient levels GO:0031667 109 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
Mouse
ribonucleotide catabolic process GO:0009261 208 0.016
positive regulation of striated muscle tissue development GO:0045844 31 0.016
regulation of microtubule based process GO:0032886 52 0.016
alcohol metabolic process GO:0006066 116 0.016
regulation of blood circulation GO:1903522 93 0.016
striated muscle hypertrophy GO:0014897 24 0.016
peptide secretion GO:0002790 114 0.016
skeletal muscle cell differentiation GO:0035914 66 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
negative regulation of systemic arterial blood pressure GO:0003085 15 0.016
phospholipid metabolic process GO:0006644 87 0.016
regulation of intracellular transport GO:0032386 159 0.016
tissue remodeling GO:0048771 102 0.015
long term synaptic depression GO:0060292 13 0.015
sensory perception of light stimulus GO:0050953 54 0.015
entry into host cell GO:0030260 15 0.015
polarity specification of proximal distal axis GO:0010085 2 0.015
cognition GO:0050890 149 0.015
morphogenesis of a branching structure GO:0001763 203 0.015
movement in environment of other organism involved in symbiotic interaction GO:0052192 15 0.015
positive regulation of renal sodium excretion GO:0035815 2 0.015
camp biosynthetic process GO:0006171 31 0.015
stem cell differentiation GO:0048863 268 0.015
peptide transport GO:0015833 133 0.015
ventral spinal cord interneuron fate determination GO:0060580 1 0.015
positive regulation of cytokine production GO:0001819 174 0.015
embryonic limb morphogenesis GO:0030326 126 0.015
response to organonitrogen compound GO:0010243 246 0.015
Rat
regulation of map kinase activity GO:0043405 120 0.015
sequestering of calcium ion GO:0051208 18 0.015
cytokine mediated signaling pathway GO:0019221 115 0.015
iron ion homeostasis GO:0055072 36 0.015
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.015
apoptotic process involved in morphogenesis GO:0060561 25 0.015
nitrogen compound transport GO:0071705 271 0.015
positive regulation of cell development GO:0010720 237 0.015
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
digestive tract morphogenesis GO:0048546 147 0.015
synaptic transmission GO:0007268 329 0.015
negative regulation of immune effector process GO:0002698 55 0.015
limbic system development GO:0021761 72 0.015
cellular response to abiotic stimulus GO:0071214 56 0.015
microtubule cytoskeleton organization GO:0000226 157 0.015
Mouse
submandibular salivary gland formation GO:0060661 1 0.015
response to radiation GO:0009314 165 0.015
glycosyl compound catabolic process GO:1901658 206 0.015
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.014
positive regulation of calcium ion transport GO:0051928 27 0.014
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.014
regulation of homeostatic process GO:0032844 182 0.014
negative regulation of organelle organization GO:0010639 90 0.014
glucose homeostasis GO:0042593 128 0.014
operant conditioning GO:0035106 2 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.014
negative regulation of nervous system development GO:0051961 156 0.014
Mouse
type b pancreatic cell fate commitment GO:0003327 1 0.014
equilibrioception GO:0050957 3 0.014
entry into other organism involved in symbiotic interaction GO:0051828 15 0.014
regulation of osteoblast differentiation GO:0045667 67 0.014
negative regulation of t cell activation GO:0050868 65 0.014
negative regulation of interleukin 5 production GO:0032714 4 0.014
cell type specific apoptotic process GO:0097285 268 0.014
regulation of ion transmembrane transporter activity GO:0032412 54 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
neurotransmitter secretion GO:0007269 62 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.014
meiotic cell cycle GO:0051321 122 0.014
ear morphogenesis GO:0042471 118 0.014
regulation of intestinal epithelial structure maintenance GO:0060730 1 0.014
detection of stimulus GO:0051606 84 0.014
skeletal system development GO:0001501 356 0.014
opioid receptor signaling pathway GO:0038003 5 0.014
mesenchymal cell differentiation involved in lung development GO:0060915 2 0.013
cardiac ventricle development GO:0003231 83 0.013
sequestering of metal ion GO:0051238 19 0.013
cardiogenic plate morphogenesis GO:0003142 1 0.013
regulation of cardioblast differentiation GO:0051890 3 0.013
regulation of membrane potential GO:0042391 192 0.013
neuropeptide signaling pathway GO:0007218 19 0.013
response to mineralocorticoid GO:0051385 1 0.013
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.013
spemann organizer formation GO:0060061 2 0.013
modification dependent macromolecule catabolic process GO:0043632 133 0.013
peptidyl lysine modification GO:0018205 77 0.013
appendage development GO:0048736 166 0.013
somatic stem cell maintenance GO:0035019 47 0.013
sleep GO:0030431 7 0.013
cell proliferation in hindbrain GO:0021534 10 0.013
response to peptide hormone GO:0043434 127 0.013
response to alkaloid GO:0043279 34 0.013
morphogenesis of a branching epithelium GO:0061138 193 0.013
regulation of hormone levels GO:0010817 211 0.013
mesenchymal cell proliferation GO:0010463 44 0.013
organic anion transport GO:0015711 137 0.013
negative regulation of inflammatory response GO:0050728 61 0.013
positive regulation of keratinocyte proliferation GO:0010838 4 0.013
cholesterol metabolic process GO:0008203 56 0.013
regulation of white fat cell proliferation GO:0070350 2 0.013
regulation of ion homeostasis GO:2000021 64 0.013
type b pancreatic cell proliferation GO:0044342 10 0.013
regulation of proteolysis GO:0030162 164 0.013
connective tissue development GO:0061448 179 0.013
gastrin induced gastric acid secretion GO:0001698 1 0.013
transforming growth factor beta receptor signaling pathway involved in primitive streak formation GO:0090010 1 0.013
lung morphogenesis GO:0060425 50 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
negative regulation of protein modification process GO:0031400 163 0.013
Mouse
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.013
exocrine pancreas development GO:0031017 7 0.013
negative regulation of epidermal cell differentiation GO:0045605 7 0.013
heart process GO:0003015 94 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012

Pax4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.014
Human
acquired metabolic disease DOID:0060158 0 0.014
Human
osteochondrodysplasia DOID:2256 0 0.014
bone development disease DOID:0080006 0 0.014
bone disease DOID:0080001 0 0.014
disease of anatomical entity DOID:7 0 0.014
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014