Mus musculus

61 known processes

Vcl

vinculin

(Aliases: 9430097D22,AW545629,AI462105,AA571387)

Vcl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell matrix adhesion GO:0007160 68 0.965
cell adhesion GO:0007155 329 0.954
cell substrate adhesion GO:0031589 130 0.936
actin cytoskeleton organization GO:0030036 220 0.911
actin filament organization GO:0007015 113 0.886
regulation of cell migration GO:0030334 219 0.853
actomyosin structure organization GO:0031032 56 0.830
regulation of cytoskeleton organization GO:0051493 122 0.786
regulation of cell adhesion GO:0030155 154 0.773
muscle cell development GO:0055001 133 0.768
single organismal cell cell adhesion GO:0016337 131 0.749
Human Mouse
positive regulation of cell migration GO:0030335 109 0.747
cell cell junction organization GO:0045216 72 0.744
Human Mouse
regulation of cell motility GO:2000145 236 0.721
cell junction assembly GO:0034329 52 0.718
Human Mouse
positive regulation of cell motility GO:2000147 116 0.713
rho protein signal transduction GO:0007266 32 0.710
myofibril assembly GO:0030239 34 0.709
adherens junction assembly GO:0034333 22 0.692
Human
regulation of actin cytoskeleton organization GO:0032956 84 0.666
morphogenesis of embryonic epithelium GO:0016331 159 0.652
cellular component assembly involved in morphogenesis GO:0010927 139 0.650
actin filament based movement GO:0030048 23 0.643
cell substrate adherens junction assembly GO:0007045 19 0.620
membrane organization GO:0061024 245 0.620
regulation of hydrolase activity GO:0051336 246 0.610
focal adhesion assembly GO:0048041 19 0.604
digestive system development GO:0055123 200 0.603
single organism cell adhesion GO:0098602 156 0.580
Human Mouse
digestive tract morphogenesis GO:0048546 147 0.567
regulation of cellular component biogenesis GO:0044087 181 0.559
gastrulation GO:0007369 116 0.554
positive regulation of apoptotic signaling pathway GO:2001235 95 0.523
Mouse
cell junction organization GO:0034330 77 0.520
Human Mouse
muscle cell differentiation GO:0042692 261 0.511
regulation of protein serine threonine kinase activity GO:0071900 157 0.505
amine metabolic process GO:0009308 45 0.504
myosin filament organization GO:0031033 3 0.494
regulation of transferase activity GO:0051338 263 0.486
engulfment of apoptotic cell GO:0043652 3 0.485
regulation of mapk cascade GO:0043408 248 0.478
digestive tract development GO:0048565 190 0.475
striated muscle cell development GO:0055002 125 0.456
blood vessel morphogenesis GO:0048514 285 0.447
regulation of protein kinase activity GO:0045859 232 0.437
lamellipodium organization GO:0097581 29 0.434
regulation of nucleoside metabolic process GO:0009118 130 0.423
body morphogenesis GO:0010171 45 0.421
cellular amine metabolic process GO:0044106 44 0.411
regulation of organelle organization GO:0033043 289 0.405
integrin mediated signaling pathway GO:0007229 27 0.403
Mouse
positive regulation of apoptotic process GO:0043065 217 0.400
Mouse
muscle contraction GO:0006936 101 0.392
cellular lipid metabolic process GO:0044255 323 0.390
regulation of cell substrate adhesion GO:0010810 73 0.381
striated muscle myosin thick filament assembly GO:0071688 1 0.363
wnt signaling pathway GO:0016055 188 0.362
response to transforming growth factor beta GO:0071559 88 0.356
regulation of cell projection organization GO:0031344 206 0.354
developmental growth involved in morphogenesis GO:0060560 138 0.354
organelle assembly GO:0070925 177 0.350
regulation of wnt signaling pathway GO:0030111 123 0.349
dendrite development GO:0016358 115 0.342
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.340
purine nucleoside metabolic process GO:0042278 241 0.340
heart morphogenesis GO:0003007 178 0.334
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.334
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.327
negative regulation of cell proliferation GO:0008285 296 0.326
Mouse
epithelial tube morphogenesis GO:0060562 303 0.325
wound healing GO:0042060 157 0.323
Human
endothelial cell differentiation GO:0045446 41 0.322
negative regulation of molecular function GO:0044092 258 0.322
ameboidal type cell migration GO:0001667 128 0.312
cell growth GO:0016049 130 0.304
cellular protein complex assembly GO:0043623 116 0.304
angiogenesis GO:0001525 201 0.303
positive regulation of programmed cell death GO:0043068 218 0.302
Mouse
syncytium formation GO:0006949 43 0.302
ras protein signal transduction GO:0007265 77 0.302
regulation of neuron projection development GO:0010975 169 0.302
myosin filament assembly GO:0031034 2 0.300
regulation of cellular catabolic process GO:0031329 242 0.299
purine nucleotide metabolic process GO:0006163 302 0.299
negative regulation of protein phosphorylation GO:0001933 126 0.298
mesoderm development GO:0007498 100 0.294
muscle system process GO:0003012 141 0.293
connective tissue development GO:0061448 179 0.292
regulation of apoptotic signaling pathway GO:2001233 197 0.290
Mouse
muscle tissue development GO:0060537 308 0.287
negative regulation of integrin mediated signaling pathway GO:2001045 2 0.286
Mouse
syncytium formation by plasma membrane fusion GO:0000768 42 0.282
coagulation GO:0050817 78 0.277
Human
ribonucleotide catabolic process GO:0009261 208 0.277
regulation of kinase activity GO:0043549 249 0.273
endocytosis GO:0006897 168 0.264
heart contraction GO:0060047 93 0.251
nucleoside phosphate metabolic process GO:0006753 338 0.250
regulation of rho protein signal transduction GO:0035023 71 0.248
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.244
purine ribonucleoside metabolic process GO:0046128 241 0.243
regulation of actin filament length GO:0030832 45 0.240
myotube differentiation GO:0014902 105 0.239
positive regulation of kinase activity GO:0033674 155 0.239
substrate adhesion dependent cell spreading GO:0034446 30 0.238
organophosphate catabolic process GO:0046434 232 0.236
peptidyl tyrosine phosphorylation GO:0018108 143 0.235
apoptotic signaling pathway GO:0097190 306 0.231
Mouse
positive regulation of transferase activity GO:0051347 167 0.229
cellular response to osmotic stress GO:0071470 7 0.227
branching morphogenesis of an epithelial tube GO:0048754 159 0.226
positive regulation of cell death GO:0010942 224 0.225
Mouse
cell fate commitment GO:0045165 210 0.223
heterocycle catabolic process GO:0046700 280 0.222
negative regulation of transferase activity GO:0051348 85 0.222
nucleobase containing small molecule metabolic process GO:0055086 352 0.221
leukocyte migration GO:0050900 124 0.220
blood coagulation GO:0007596 76 0.218
Human
actin mediated cell contraction GO:0070252 15 0.214
cell substrate junction assembly GO:0007044 24 0.213
cell migration involved in gastrulation GO:0042074 13 0.207
positive regulation of protein phosphorylation GO:0001934 242 0.207
neuron projection extension GO:1990138 64 0.206
chemotaxis GO:0006935 247 0.206
response to peptide GO:1901652 136 0.204
response to organonitrogen compound GO:0010243 246 0.203
nucleoside catabolic process GO:0009164 206 0.203
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.202
establishment or maintenance of cell polarity GO:0007163 86 0.199
Mouse
negative regulation of kinase activity GO:0033673 81 0.197
striated muscle tissue development GO:0014706 293 0.197
apical junction assembly GO:0043297 15 0.195
Human Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.195
organonitrogen compound catabolic process GO:1901565 264 0.194
regulation of purine nucleotide metabolic process GO:1900542 169 0.191
purine nucleoside triphosphate catabolic process GO:0009146 203 0.190
extrinsic apoptotic signaling pathway GO:0097191 126 0.190
Mouse
cytosolic calcium ion transport GO:0060401 48 0.189
negative regulation of cellular component organization GO:0051129 194 0.188
macromolecule catabolic process GO:0009057 281 0.187
Worm
regionalization GO:0003002 337 0.186
regulation of membrane potential GO:0042391 192 0.186
peptidyl threonine modification GO:0018210 31 0.186
positive regulation of protein kinase activity GO:0045860 144 0.185
adherens junction organization GO:0034332 28 0.184
Human
regulation of cell shape GO:0008360 39 0.182
platelet aggregation GO:0070527 20 0.182
Human
regulation of hepatocyte proliferation GO:2000345 6 0.181
ribonucleotide metabolic process GO:0009259 291 0.180
ribonucleoside catabolic process GO:0042454 206 0.179
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.179
keratinocyte differentiation GO:0030216 48 0.175
nucleoside phosphate catabolic process GO:1901292 222 0.174
cellular ion homeostasis GO:0006873 165 0.174
positive regulation of cell adhesion GO:0045785 80 0.172
positive regulation of cellular component biogenesis GO:0044089 94 0.171
glycosyl compound catabolic process GO:1901658 206 0.170
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.165
negative regulation of phosphate metabolic process GO:0045936 184 0.164
determination of left right symmetry GO:0007368 80 0.163
membrane invagination GO:0010324 17 0.162
positive regulation of hydrolase activity GO:0051345 148 0.161
circulatory system process GO:0003013 197 0.160
morphogenesis of a branching epithelium GO:0061138 193 0.158
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.158
respiratory tube development GO:0030323 167 0.155
cellular nitrogen compound catabolic process GO:0044270 280 0.155
positive regulation of cell development GO:0010720 237 0.154
regulation of cell projection assembly GO:0060491 38 0.153
microtubule cytoskeleton organization GO:0000226 157 0.152
oocyte construction GO:0007308 2 0.152
kidney development GO:0001822 213 0.150
axonogenesis GO:0007409 274 0.149
maintenance of location GO:0051235 89 0.148
Worm
platelet activation GO:0030168 40 0.146
Human
negative regulation of epithelial cell proliferation GO:0050680 64 0.143
purine containing compound catabolic process GO:0072523 213 0.142
positive regulation of gtp catabolic process GO:0033126 85 0.142
endomembrane system organization GO:0010256 147 0.142
response to alcohol GO:0097305 48 0.141
positive regulation of ras protein signal transduction GO:0046579 13 0.139
carbohydrate derivative catabolic process GO:1901136 231 0.139
endoderm development GO:0007492 45 0.137
regulation of endocytosis GO:0030100 69 0.137
cytoskeletal anchoring at plasma membrane GO:0007016 2 0.136
Worm
mapk cascade GO:0000165 281 0.136
positive regulation of organelle organization GO:0010638 128 0.136
regulation of actin polymerization or depolymerization GO:0008064 45 0.135
purine nucleoside triphosphate metabolic process GO:0009144 226 0.134
regulation of striated muscle cell differentiation GO:0051153 81 0.134
peptidyl amino acid modification GO:0018193 336 0.133
neural precursor cell proliferation GO:0061351 121 0.133
Mouse
positive regulation of cell projection organization GO:0031346 95 0.133
cellular response to growth factor stimulus GO:0071363 197 0.133
smoothened signaling pathway GO:0007224 105 0.133
Mouse
regulation of actin filament based process GO:0032970 99 0.132
epithelial cell morphogenesis GO:0003382 41 0.131
formation of primary germ layer GO:0001704 77 0.128
regulation of body fluid levels GO:0050878 162 0.127
Human
positive regulation of mapk cascade GO:0043410 170 0.126
positive regulation of chemotaxis GO:0050921 38 0.126
actin cytoskeleton reorganization GO:0031532 21 0.126
myeloid leukocyte activation GO:0002274 83 0.125
aromatic compound catabolic process GO:0019439 286 0.122
t cell activation GO:0042110 289 0.120
guanosine containing compound metabolic process GO:1901068 144 0.120
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.118
Mouse
cell chemotaxis GO:0060326 81 0.118
response to growth factor GO:0070848 198 0.116
protein localization to membrane GO:0072657 108 0.116
glial cell differentiation GO:0010001 131 0.115
organic cyclic compound catabolic process GO:1901361 295 0.115
positive regulation of map kinase activity GO:0043406 84 0.114
nucleotide metabolic process GO:0009117 332 0.113
homotypic cell cell adhesion GO:0034109 28 0.113
Human
response to oxidative stress GO:0006979 123 0.113
glycosyl compound metabolic process GO:1901657 246 0.112
sarcomere organization GO:0045214 24 0.112
leukocyte cell cell adhesion GO:0007159 14 0.112
regulation of osteoblast differentiation GO:0045667 67 0.112
integrin activation GO:0033622 8 0.111
purine ribonucleotide metabolic process GO:0009150 290 0.111
urogenital system development GO:0001655 261 0.110
skeletal muscle organ development GO:0060538 163 0.110
extracellular structure organization GO:0043062 148 0.109
regulation of vesicle mediated transport GO:0060627 139 0.109
synapse organization GO:0050808 125 0.106
Mouse
negative regulation of protein modification process GO:0031400 163 0.106
regulation of microtubule based process GO:0032886 52 0.104
protein processing GO:0016485 163 0.104
phagocytosis GO:0006909 66 0.103
regulation of t cell activation GO:0050863 170 0.103
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.103
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.102
regulation of cytokine production GO:0001817 266 0.102
regulation of fat cell differentiation GO:0045598 81 0.102
microtubule based process GO:0007017 236 0.102
cation transport GO:0006812 399 0.100
cation homeostasis GO:0055080 212 0.100
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.099
guanosine containing compound catabolic process GO:1901069 144 0.099
small gtpase mediated signal transduction GO:0007264 97 0.099
extracellular matrix organization GO:0030198 147 0.098
negative regulation of phosphorylation GO:0042326 166 0.096
cytokine production GO:0001816 319 0.096
regulation of organ morphogenesis GO:2000027 144 0.095
organelle localization GO:0051640 179 0.095
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.094
protein catabolic process GO:0030163 221 0.094
Worm
cellular response to inorganic substance GO:0071241 37 0.094
regulation of rho gtpase activity GO:0032319 58 0.094
regulation of cellular component size GO:0032535 121 0.094
nucleoside metabolic process GO:0009116 246 0.094
response to peptide hormone GO:0043434 127 0.093
regulation of neuron differentiation GO:0045664 281 0.092
positive regulation of neuron projection development GO:0010976 79 0.092
negative regulation of hepatocyte proliferation GO:2000346 3 0.091
apical constriction GO:0003383 4 0.091
purine ribonucleoside catabolic process GO:0046130 205 0.090
neuron projection guidance GO:0097485 141 0.089
protein localization to organelle GO:0033365 185 0.089
stress activated protein kinase signaling cascade GO:0031098 81 0.089
regulation of map kinase activity GO:0043405 120 0.089
stem cell differentiation GO:0048863 268 0.089
muscle fiber development GO:0048747 76 0.089
regulation of cellular ketone metabolic process GO:0010565 66 0.088
regulation of cellular response to stress GO:0080135 159 0.088
camera type eye development GO:0043010 266 0.087
regulation of ion homeostasis GO:2000021 64 0.086
ribonucleoside metabolic process GO:0009119 245 0.086
regulation of epithelial cell proliferation GO:0050678 141 0.086
cellular response to hormone stimulus GO:0032870 150 0.085
odontogenesis of dentin containing tooth GO:0042475 66 0.085
regulation of purine nucleotide catabolic process GO:0033121 122 0.085
regulation of ossification GO:0030278 112 0.084
germ cell development GO:0007281 185 0.084
cell adhesion mediated by integrin GO:0033627 18 0.082
regulation of actin filament polymerization GO:0030833 38 0.081
regulation of protein localization GO:0032880 231 0.080
response to organic cyclic compound GO:0014070 198 0.080
gonad development GO:0008406 141 0.080
mitotic cell cycle process GO:1903047 159 0.080
endothelial cell proliferation GO:0001935 27 0.080
establishment of organelle localization GO:0051656 122 0.080
positive regulation of cell activation GO:0050867 158 0.079
neuromuscular process GO:0050905 99 0.079
Mouse
epithelial cell migration GO:0010631 63 0.079
positive regulation of protein modification process GO:0031401 299 0.079
epithelial cell development GO:0002064 159 0.078
positive regulation of nucleotide catabolic process GO:0030813 88 0.078
positive regulation of nucleotide metabolic process GO:0045981 114 0.078
protein localization to plasma membrane GO:0072659 57 0.078
organelle fission GO:0048285 170 0.077
positive regulation of filopodium assembly GO:0051491 10 0.077
ubiquitin dependent protein catabolic process GO:0006511 129 0.077
dendritic spine organization GO:0097061 26 0.077
regulation of peptidase activity GO:0052547 96 0.077
regulation of proteolysis GO:0030162 164 0.076
renal system development GO:0072001 225 0.076
regulation of wound healing GO:0061041 40 0.075
dna metabolic process GO:0006259 303 0.075
actin polymerization or depolymerization GO:0008154 54 0.075
axon guidance GO:0007411 141 0.075
locomotory behavior GO:0007626 195 0.074
regulation of anatomical structure size GO:0090066 178 0.074
cellular response to lipid GO:0071396 145 0.074
purine containing compound metabolic process GO:0072521 311 0.074
regulation of lamellipodium assembly GO:0010591 3 0.074
regulation of epithelial cell migration GO:0010632 35 0.073
morphogenesis of a branching structure GO:0001763 203 0.073
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.072
peptidyl threonine phosphorylation GO:0018107 31 0.072
regulation of protein transport GO:0051223 163 0.071
regulation of microtubule cytoskeleton organization GO:0070507 37 0.071
regulation of gtp catabolic process GO:0033124 113 0.070
kidney epithelium development GO:0072073 121 0.070
gland development GO:0048732 330 0.070
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.070
Mouse
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.069
Mouse
regulation of myotube differentiation GO:0010830 62 0.069
skeletal system development GO:0001501 356 0.069
regulation of cell cycle GO:0051726 281 0.069
stem cell development GO:0048864 219 0.069
modification dependent protein catabolic process GO:0019941 133 0.068
heart process GO:0003015 94 0.068
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.067
mesoderm morphogenesis GO:0048332 64 0.067
ribonucleoside triphosphate metabolic process GO:0009199 220 0.067
positive regulation of rho gtpase activity GO:0032321 41 0.066
fat cell differentiation GO:0045444 160 0.066
positive regulation of cytoskeleton organization GO:0051495 49 0.065
negative regulation of cell motility GO:2000146 61 0.065
Mouse
skin development GO:0043588 220 0.065
cartilage development GO:0051216 140 0.065
cellularization GO:0007349 1 0.064
respiratory system development GO:0060541 190 0.064
negative regulation of cell development GO:0010721 169 0.064
Mouse
protein targeting GO:0006605 143 0.064
intracellular protein transport GO:0006886 204 0.064
regulation of synapse structural plasticity GO:0051823 4 0.064
Mouse
oocyte axis specification GO:0007309 2 0.064
regulation of cell adhesion mediated by integrin GO:0033628 13 0.064
peptidyl serine modification GO:0018209 83 0.063
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.063
tissue remodeling GO:0048771 102 0.062
cellular response to oxidative stress GO:0034599 76 0.061
cellular divalent inorganic cation homeostasis GO:0072503 127 0.061
purine nucleotide catabolic process GO:0006195 211 0.060
regulation of defense response GO:0031347 233 0.060
response to inorganic substance GO:0010035 96 0.060
regulation of homeostatic process GO:0032844 182 0.060
epidermis development GO:0008544 187 0.060
negative regulation of apoptotic signaling pathway GO:2001234 104 0.059
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.059
endothelium development GO:0003158 45 0.059
regulation of system process GO:0044057 200 0.059
glucose transport GO:0015758 56 0.059
regulation of muscle system process GO:0090257 80 0.058
cellular response to calcium ion GO:0071277 14 0.058
midgut development GO:0007494 4 0.058
cellular ketone metabolic process GO:0042180 84 0.058
defecation GO:0030421 1 0.058
regulation of nucleotide catabolic process GO:0030811 122 0.057
establishment of protein localization to membrane GO:0090150 54 0.056
neuron migration GO:0001764 122 0.056
positive regulation of cell substrate adhesion GO:0010811 47 0.056
lymphocyte migration GO:0072676 26 0.056
positive regulation of gtpase activity GO:0043547 85 0.056
positive regulation of osteoblast differentiation GO:0045669 34 0.056
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.056
hemostasis GO:0007599 78 0.056
Human
sequestering of metal ion GO:0051238 19 0.056
cellular response to peptide hormone stimulus GO:0071375 92 0.056
regulation of dendritic spine development GO:0060998 22 0.055
positive regulation of determination of dorsal identity GO:2000017 2 0.055
cellular response to organonitrogen compound GO:0071417 145 0.055
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.055
cardiocyte differentiation GO:0035051 87 0.054
cellular response to acid chemical GO:0071229 68 0.054
regulation of angiogenesis GO:0045765 81 0.054
female gamete generation GO:0007292 74 0.054
positive regulation of lymphocyte activation GO:0051251 140 0.053
negative regulation of neuron apoptotic process GO:0043524 92 0.052
establishment of protein localization to organelle GO:0072594 118 0.052
cellular amino acid metabolic process GO:0006520 103 0.052
regulation of integrin mediated signaling pathway GO:2001044 8 0.052
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.052
developmental maturation GO:0021700 193 0.052
leukocyte homeostasis GO:0001776 79 0.052
positive regulation of angiogenesis GO:0045766 46 0.052
positive regulation of endocytosis GO:0045807 42 0.052
negative regulation of actin filament depolymerization GO:0030835 9 0.051
skeletal system morphogenesis GO:0048705 203 0.051
fibrinolysis GO:0042730 3 0.051
leukocyte chemotaxis GO:0030595 69 0.051
cognition GO:0050890 149 0.051
nucleoside triphosphate metabolic process GO:0009141 230 0.051
lipid localization GO:0010876 126 0.051
positive regulation of secretion GO:0051047 130 0.051
modification dependent macromolecule catabolic process GO:0043632 133 0.050
negative regulation of nervous system development GO:0051961 156 0.050
Mouse
lens development in camera type eye GO:0002088 62 0.050
vasoconstriction GO:0042310 27 0.050
stress activated mapk cascade GO:0051403 80 0.050
cellular metal ion homeostasis GO:0006875 151 0.050
negative regulation of phosphorus metabolic process GO:0010563 184 0.049
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.049
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.049
transmission of nerve impulse GO:0019226 76 0.049
microtubule based movement GO:0007018 84 0.049
protein maturation GO:0051604 176 0.049
peptidyl serine phosphorylation GO:0018105 74 0.049
regulation of blood pressure GO:0008217 93 0.049
actin filament polymerization GO:0030041 44 0.048
nucleotide catabolic process GO:0009166 217 0.048
sequestering of calcium ion GO:0051208 18 0.048
granulocyte migration GO:0097530 43 0.048
negative regulation of synapse assembly GO:0051964 3 0.048
gtp metabolic process GO:0046039 144 0.048
positive regulation of response to wounding GO:1903036 66 0.048
positive regulation of nervous system development GO:0051962 221 0.048
venous blood vessel development GO:0060841 13 0.048
regulation of cell activation GO:0050865 289 0.047
regulation of neuron death GO:1901214 134 0.047
endothelial cell migration GO:0043542 44 0.047
regulation of ras gtpase activity GO:0032318 88 0.046
positive regulation of cell growth GO:0030307 33 0.046
cellular response to peptide GO:1901653 92 0.046
regulation of synapse assembly GO:0051963 29 0.046
maternal determination of anterior posterior axis embryo GO:0008358 2 0.046
stem cell maintenance GO:0019827 130 0.046
regulation of systemic arterial blood pressure GO:0003073 61 0.045
mesoderm formation GO:0001707 62 0.045
myeloid leukocyte differentiation GO:0002573 119 0.045
granulocyte chemotaxis GO:0071621 39 0.045
response to reactive oxygen species GO:0000302 56 0.045
maintenance of location in cell GO:0051651 24 0.045
Worm
positive regulation of axon extension GO:0045773 20 0.045
positive regulation of cellular amine metabolic process GO:0033240 5 0.044
purine nucleoside catabolic process GO:0006152 205 0.044
positive regulation of neuron differentiation GO:0045666 141 0.044
purine ribonucleotide catabolic process GO:0009154 208 0.044
response to acid chemical GO:0001101 111 0.044
liver development GO:0001889 66 0.044
positive regulation of behavior GO:0048520 40 0.044
myeloid cell differentiation GO:0030099 233 0.043
cytoplasmic transport GO:0016482 234 0.043
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.043
cellular chemical homeostasis GO:0055082 215 0.043
regulation of cellular amino acid metabolic process GO:0006521 5 0.042
neural tube formation GO:0001841 108 0.042
ossification GO:0001503 216 0.042
telencephalon development GO:0021537 186 0.042
synaptic transmission GO:0007268 329 0.042
Mouse
ribose phosphate metabolic process GO:0019693 291 0.042
embryonic organ morphogenesis GO:0048562 276 0.042
cellular response to molecule of bacterial origin GO:0071219 83 0.042
skeletal muscle fiber development GO:0048741 58 0.041
regulation of b cell tolerance induction GO:0002661 2 0.041
blastocyst development GO:0001824 80 0.041
negative regulation of neuron death GO:1901215 98 0.041
response to insulin GO:0032868 100 0.041
nephron development GO:0072006 109 0.041
action potential GO:0001508 78 0.041
developmental cell growth GO:0048588 84 0.041
regulation of muscle contraction GO:0006937 49 0.041
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.040
cell type specific apoptotic process GO:0097285 268 0.040
schwann cell development GO:0014044 22 0.040
radial glia guided migration of purkinje cell GO:0021942 6 0.040
Mouse
regulation of extent of cell growth GO:0061387 52 0.040
positive regulation of homeostatic process GO:0032846 64 0.040
calcium ion transport GO:0006816 159 0.040
cellular response to biotic stimulus GO:0071216 92 0.040
tissue migration GO:0090130 68 0.040
receptor mediated endocytosis GO:0006898 51 0.040
actin filament depolymerization GO:0030042 15 0.039
dorsal ventral axon guidance GO:0033563 3 0.039
regulation of protein binding GO:0043393 60 0.039
lateral inhibition GO:0046331 1 0.039
regulation of phagocytosis GO:0050764 33 0.039
microtubule polymerization or depolymerization GO:0031109 26 0.039
mesenchymal cell development GO:0014031 93 0.039
somitogenesis GO:0001756 69 0.039
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.039
regulation of vasculature development GO:1901342 88 0.039
multicellular organism growth GO:0035264 161 0.039
anion transport GO:0006820 177 0.038

Vcl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
heart disease DOID:114 0 0.611
Human
disease of anatomical entity DOID:7 0 0.611
Human
cardiovascular system disease DOID:1287 0 0.611
Human
muscular disease DOID:0080000 0 0.120
Human
musculoskeletal system disease DOID:17 0 0.120
Human
artery disease DOID:0050828 0 0.047
vascular disease DOID:178 0 0.047
myopathy DOID:423 0 0.042
Human
cardiomyopathy DOID:0050700 0 0.042
Human
intrinsic cardiomyopathy DOID:0060036 0 0.042
Human
muscle tissue disease DOID:66 0 0.042
Human