|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.997
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.994
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.993
|
Worm |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.992
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.984
|
Human Yeast Zebrafish |
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.979
|
|
|
|
inclusion body assembly
|
GO:0070841 |
3 |
0.972
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.962
|
Human Yeast Rat Worm |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.955
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.853
|
Human Yeast Zebrafish |
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.829
|
Human Yeast Zebrafish |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.815
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.799
|
Human Yeast Rat Worm |
|
|
cellular response to misfolded protein
|
GO:0071218 |
5 |
0.773
|
Yeast Worm |
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.703
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.649
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.630
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.600
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.593
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
25 |
0.584
|
Yeast Worm |
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
19 |
0.532
|
Worm |
|
|
regulation of transposition
|
GO:0010528 |
2 |
0.524
|
|
|
|
misfolded protein transport
|
GO:0070843 |
1 |
0.523
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.516
|
Human Zebrafish Rat |
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.471
|
|
|
|
membrane fusion
|
GO:0061025 |
38 |
0.433
|
Yeast |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.389
|
Human Yeast |
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
57 |
0.375
|
Yeast Rat Worm |
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.342
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.342
|
Yeast |
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.311
|
Human |
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.306
|
|
|
|
atp catabolic process
|
GO:0006200 |
55 |
0.302
|
Yeast Rat Worm |
|
|
granzyme mediated apoptotic signaling pathway
|
GO:0008626 |
1 |
0.285
|
|
|
|
proteasome assembly
|
GO:0043248 |
1 |
0.271
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.263
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.256
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.247
|
Yeast |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
52 |
0.233
|
Yeast Zebrafish |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.230
|
Yeast |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.229
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.221
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.217
|
|
|
|
negative regulation of transposition
|
GO:0010529 |
2 |
0.213
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.212
|
Human |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.203
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.184
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
26 |
0.169
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.164
|
Yeast Rat Worm |
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
59 |
0.161
|
Yeast Rat Worm |
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.159
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.148
|
Yeast |
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.134
|
Yeast |
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.134
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.132
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.131
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.130
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
58 |
0.130
|
Yeast Rat Worm |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.128
|
Human |
|
|
response to misfolded protein
|
GO:0051788 |
5 |
0.123
|
Yeast Worm |
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.121
|
Yeast |
|
|
dna repair
|
GO:0006281 |
107 |
0.120
|
Human |
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.117
|
Human |
|
|
fertilization
|
GO:0009566 |
127 |
0.111
|
|
|
|
heart trabecula morphogenesis
|
GO:0061384 |
26 |
0.109
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.106
|
Human |
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
3 |
0.105
|
|
|
|
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway
|
GO:0043162 |
3 |
0.102
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.102
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.100
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.100
|
Yeast Rat Worm |
|
|
regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0045898 |
2 |
0.099
|
|
|
|
response to unfolded protein
|
GO:0006986 |
21 |
0.097
|
Worm |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.095
|
Yeast Rat Worm |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.094
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.094
|
|
|
|
response to topologically incorrect protein
|
GO:0035966 |
25 |
0.093
|
Yeast Worm |
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.093
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.092
|
Yeast Rat Worm |
|
|
gonad development
|
GO:0008406 |
141 |
0.092
|
Worm |
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
19 |
0.090
|
|
|
|
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0045899 |
2 |
0.090
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.088
|
Yeast Rat Worm |
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.088
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.087
|
Human Zebrafish Rat |
|
|
regulation of protein import into nucleus translocation
|
GO:0033158 |
2 |
0.086
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.086
|
Human Yeast |
|
|
protein deacylation
|
GO:0035601 |
36 |
0.084
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
43 |
0.083
|
Yeast |
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.082
|
Yeast Rat Worm |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.082
|
Yeast Rat Worm |
|
|
germ cell development
|
GO:0007281 |
185 |
0.081
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.081
|
Yeast |
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.080
|
Yeast Rat Worm |
|
|
response to uv
|
GO:0009411 |
44 |
0.080
|
|
|
|
negative regulation of microtubule polymerization or depolymerization
|
GO:0031111 |
15 |
0.079
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.078
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.076
|
Yeast Rat Worm |
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
3 |
0.076
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.075
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.074
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.074
|
|
|
|
trabecula morphogenesis
|
GO:0061383 |
40 |
0.074
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.073
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.072
|
Yeast Rat Worm |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.071
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.071
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.070
|
Human Zebrafish Rat |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.069
|
Yeast Rat Worm |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.068
|
Yeast Rat Worm |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.067
|
Yeast Rat Worm |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.066
|
Human |
|
|
organelle assembly
|
GO:0070925 |
177 |
0.066
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.066
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.066
|
|
|
|
cardiac muscle tissue morphogenesis
|
GO:0055008 |
44 |
0.065
|
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
27 |
0.063
|
Worm |
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.063
|
|
|
|
rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0051123 |
3 |
0.062
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.062
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.061
|
Human Rat |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.060
|
|
|
|
protein refolding
|
GO:0042026 |
1 |
0.059
|
|
|
|
rna interference
|
GO:0016246 |
2 |
0.057
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.057
|
Yeast Rat Worm |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.057
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.057
|
Yeast |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.057
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.056
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.055
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.055
|
Yeast Rat Worm |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.055
|
Yeast Rat Worm |
|
|
protein modification by small protein removal
|
GO:0070646 |
21 |
0.055
|
Human |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.054
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.054
|
Yeast Rat Worm |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.054
|
Yeast Rat Worm |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.054
|
Rat |
|
|
aggresome assembly
|
GO:0070842 |
2 |
0.054
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.054
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.054
|
Yeast Rat Worm |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.054
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.053
|
Yeast |
|
|
histone deacetylation
|
GO:0016575 |
26 |
0.053
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.053
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.053
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.052
|
Yeast Rat Worm |
|
|
oocyte development
|
GO:0048599 |
33 |
0.051
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.051
|
Yeast Rat Worm |
|
|
autophagy
|
GO:0006914 |
45 |
0.051
|
Yeast |
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.050
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.050
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
37 |
0.050
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.050
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
52 |
0.050
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.049
|
Yeast Rat Worm |
|
|
protein folding
|
GO:0006457 |
28 |
0.049
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.048
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.047
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.047
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.047
|
|
|
|
sperm egg recognition
|
GO:0035036 |
37 |
0.046
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.046
|
Human |
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.046
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.046
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.046
|
Yeast Rat Worm |
|
|
protein depolymerization
|
GO:0051261 |
34 |
0.046
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.045
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.045
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.045
|
Yeast Rat Worm |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.045
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.044
|
Yeast Rat Worm |
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.043
|
Yeast Rat Worm |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.043
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
57 |
0.042
|
Yeast Rat Worm |
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.042
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.042
|
Yeast Rat Worm |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.042
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.042
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
28 |
0.042
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.042
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
80 |
0.042
|
Yeast Rat Worm |
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
23 |
0.041
|
Human Rat |
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.041
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
83 |
0.041
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.041
|
|
|
|
atp metabolic process
|
GO:0046034 |
75 |
0.041
|
Yeast Rat Worm |
|
|
single fertilization
|
GO:0007338 |
82 |
0.041
|
|
|
|
protein complex disassembly
|
GO:0043241 |
40 |
0.041
|
Yeast |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.040
|
Yeast Rat Worm |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.040
|
Yeast Rat Worm |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.040
|
Yeast Rat Worm |
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.040
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.040
|
Yeast Rat Worm |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.039
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.039
|
Yeast |
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
14 |
0.039
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.039
|
Yeast |
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.039
|
|
|
|
protein deacetylation
|
GO:0006476 |
32 |
0.038
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.038
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.038
|
Yeast Rat Worm |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.038
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.038
|
Human Zebrafish Rat |
|
|
microtubule cytoskeleton organization involved in mitosis
|
GO:1902850 |
4 |
0.038
|
Yeast |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.038
|
Yeast |
|
|
female gamete generation
|
GO:0007292 |
74 |
0.038
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.037
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.037
|
Yeast Rat Worm |
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.037
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
81 |
0.036
|
Yeast Rat Worm |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.036
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.036
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.036
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.036
|
Yeast |
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.036
|
Yeast Rat Worm |
|
|
muscle tissue morphogenesis
|
GO:0060415 |
53 |
0.036
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.036
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.035
|
|
|
|
regulation of protein depolymerization
|
GO:1901879 |
26 |
0.035
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.035
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.035
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.034
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.034
|
Yeast |
|
|
developmental maturation
|
GO:0021700 |
193 |
0.034
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.034
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.034
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.033
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.033
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.033
|
Yeast Worm |
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.033
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.033
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.033
|
Yeast Rat Worm |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.032
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.032
|
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.031
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.031
|
|
|
|
binding of sperm to zona pellucida
|
GO:0007339 |
34 |
0.031
|
|
|
|
cellular protein complex disassembly
|
GO:0043624 |
36 |
0.031
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.031
|
Yeast |
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.031
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.030
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.030
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.030
|
Yeast Rat Worm |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.030
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.029
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.029
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.029
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
80 |
0.029
|
Yeast Rat Worm |
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.029
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.029
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
9 |
0.029
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.029
|
Yeast |
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.029
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.029
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.029
|
Yeast |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.028
|
Yeast Rat Worm |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.028
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.028
|
Worm |
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.028
|
|
|
|
golgi organization
|
GO:0007030 |
9 |
0.028
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.028
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
35 |
0.028
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.028
|
Yeast |
|
|
receptor biosynthetic process
|
GO:0032800 |
3 |
0.027
|
|
|
|
rna dependent dna replication
|
GO:0006278 |
3 |
0.027
|
|
|
|
response to xenobiotic stimulus
|
GO:0009410 |
13 |
0.027
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.027
|
|
|
|
ventricular cardiac muscle tissue morphogenesis
|
GO:0055010 |
32 |
0.027
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
1 |
0.027
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.027
|
Yeast Rat Worm |
|
|
action potential
|
GO:0001508 |
78 |
0.027
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.027
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.026
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.026
|
Yeast |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.026
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.026
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.026
|
|
|
|
tubulin deacetylation
|
GO:0090042 |
4 |
0.025
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.025
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.025
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.025
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.025
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.025
|
Yeast Rat Worm |
|
|
positive regulation of protein import into nucleus translocation
|
GO:0033160 |
1 |
0.024
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.024
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.024
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.024
|
|
|
|
cerebellar cortex development
|
GO:0021695 |
48 |
0.024
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.024
|
|
|
|
negative regulation of protein depolymerization
|
GO:1901880 |
21 |
0.024
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.024
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.024
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.024
|
|
|
|
ventricular cardiac muscle tissue development
|
GO:0003229 |
38 |
0.023
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
20 |
0.023
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.023
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.023
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.023
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
37 |
0.023
|
|
|
|
dna templated transcriptional preinitiation complex assembly
|
GO:0070897 |
4 |
0.023
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.023
|
|
|
|
protein targeting to membrane
|
GO:0006612 |
20 |
0.023
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.023
|
Yeast |
|
|
positive regulation of cellular response to oxidative stress
|
GO:1900409 |
6 |
0.022
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.022
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.022
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
19 |
0.022
|
|
|
|
circadian behavior
|
GO:0048512 |
13 |
0.022
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.022
|
Yeast |
|
|
regulation of microtubule depolymerization
|
GO:0031114 |
13 |
0.022
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.022
|
|
|
|
cardiac ventricle morphogenesis
|
GO:0003208 |
50 |
0.022
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.022
|
|
|
|
amino acid activation
|
GO:0043038 |
1 |
0.022
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.022
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.022
|
|
|
|
positive regulation of protein binding
|
GO:0032092 |
29 |
0.022
|
|
|
|
regulation of epidermal cell division
|
GO:0010482 |
3 |
0.022
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.021
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.021
|
|
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.021
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.021
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.021
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
36 |
0.021
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.021
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.021
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.020
|
|
|
|
positive regulation of binding
|
GO:0051099 |
49 |
0.020
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.020
|
Rat |
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.020
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.020
|
|
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.020
|
|
|
|
pore complex assembly
|
GO:0046931 |
3 |
0.020
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
5 |
0.020
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.020
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.020
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.020
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.020
|
|
|
|
peptidyl lysine deacetylation
|
GO:0034983 |
1 |
0.019
|
|
|
|
cellular response to interleukin 4
|
GO:0071353 |
21 |
0.019
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.019
|
Human Rat |
|
|
protein dna complex subunit organization
|
GO:0071824 |
28 |
0.019
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.019
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.019
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.019
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.019
|
|
|
|
telomere maintenance via telomerase
|
GO:0007004 |
1 |
0.019
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
36 |
0.019
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.019
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.019
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.018
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.018
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.018
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.018
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.018
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.018
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.018
|
Yeast |
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.018
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.018
|
Yeast Rat Worm |
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.018
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.018
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.018
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.018
|
|
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
2 |
0.018
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
25 |
0.018
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.017
|
Worm |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.017
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.017
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.017
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.017
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.017
|
|
|
|
posttranscriptional gene silencing
|
GO:0016441 |
10 |
0.017
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.017
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.017
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.017
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.017
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.017
|
|
|
|
regulation of response to reactive oxygen species
|
GO:1901031 |
9 |
0.017
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.017
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.017
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.017
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.017
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.017
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.016
|
Worm |
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.016
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.016
|
Yeast |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.016
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.016
|
Yeast |
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.016
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.016
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
22 |
0.016
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.016
|
Yeast |
|
|
response to heat
|
GO:0009408 |
27 |
0.016
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.016
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.016
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.016
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.016
|
|
|
|
nucleotide excision repair
|
GO:0006289 |
13 |
0.016
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.016
|
Yeast |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.016
|
|
|
|
gene silencing by rna
|
GO:0031047 |
19 |
0.015
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
61 |
0.015
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.015
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.015
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.015
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.015
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
22 |
0.015
|
|
|
|
positive regulation of transmembrane transport
|
GO:0034764 |
29 |
0.015
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.015
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.015
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.015
|
|
|
|
spindle organization
|
GO:0007051 |
28 |
0.015
|
Yeast |
|
|
er associated ubiquitin dependent protein catabolic process
|
GO:0030433 |
10 |
0.015
|
Human Yeast Worm |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.015
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.015
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.015
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.015
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
9 |
0.015
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.015
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
30 |
0.015
|
|
|
|
inner cell mass cell proliferation
|
GO:0001833 |
15 |
0.015
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.015
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.015
|
|
|
|
cytoplasmic translational initiation
|
GO:0002183 |
3 |
0.015
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.015
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.015
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.015
|
|
|
|
regulation of protein complex disassembly
|
GO:0043244 |
28 |
0.015
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.015
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.014
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.014
|
|
|
|
spindle assembly involved in mitosis
|
GO:0090307 |
4 |
0.014
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
77 |
0.014
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.014
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
29 |
0.014
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.014
|
|
|
|
trna aminoacylation for protein translation
|
GO:0006418 |
1 |
0.014
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.014
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.014
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.014
|
|
|
|
transition metal ion transport
|
GO:0000041 |
38 |
0.014
|
|
|
|
regulation of inclusion body assembly
|
GO:0090083 |
1 |
0.014
|
|
|
|
thermosensory behavior
|
GO:0040040 |
1 |
0.014
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.014
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.014
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.014
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.014
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.014
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
28 |
0.014
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.013
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.013
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.013
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.013
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.013
|
|
|
|
mrna metabolic process
|
GO:0016071 |
84 |
0.013
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.013
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.013
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.013
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.013
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.013
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.013
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.013
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.013
|
|
|
|
regulation of translational initiation
|
GO:0006446 |
15 |
0.013
|
|
|
|
positive regulation of receptor biosynthetic process
|
GO:0010870 |
1 |
0.013
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.013
|
Worm |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.013
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.013
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.013
|
|
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
22 |
0.013
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.012
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.012
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.012
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.012
|
Yeast |
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.012
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.012
|
|
|
|
meiosis i
|
GO:0007127 |
60 |
0.012
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.012
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.012
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.012
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
21 |
0.012
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.012
|
Worm |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.012
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.012
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
41 |
0.012
|
|
|
|
positive regulation of response to oxidative stress
|
GO:1902884 |
6 |
0.012
|
|
