Mus musculus

10 known processes

Chd1

chromodomain helicase DNA binding protein 1

(Aliases: MGC141554,AI851787,AW555109,4930525N21Rik)

Chd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatogenesis GO:0007283 284 0.312
dna metabolic process GO:0006259 303 0.293
Yeast
homeostasis of number of cells GO:0048872 210 0.241
covalent chromatin modification GO:0016569 163 0.231
Yeast
rna 3 end processing GO:0031123 20 0.153
leukocyte differentiation GO:0002521 342 0.123
histone modification GO:0016570 159 0.112
Yeast
regulation of lymphocyte activation GO:0051249 240 0.079
regulation of cell activation GO:0050865 289 0.073
chromatin modification GO:0016568 187 0.058
neural tube development GO:0021915 160 0.056
axonogenesis GO:0007409 274 0.055
chromatin organization GO:0006325 206 0.055
male gamete generation GO:0048232 285 0.055
germ cell development GO:0007281 185 0.054
camera type eye development GO:0043010 266 0.054
negative regulation of protein metabolic process GO:0051248 282 0.053
Yeast
nuclear division GO:0000280 158 0.053
cellular amino acid metabolic process GO:0006520 103 0.052
myeloid cell differentiation GO:0030099 233 0.052
retina development in camera type eye GO:0060041 119 0.051
rhythmic process GO:0048511 174 0.051
regulation of organelle organization GO:0033043 289 0.050
Yeast
b cell activation GO:0042113 161 0.047
cellular response to dna damage stimulus GO:0006974 207 0.045
myeloid cell homeostasis GO:0002262 114 0.045
compound eye development GO:0048749 1 0.045
embryonic epithelial tube formation GO:0001838 130 0.044
aromatic compound catabolic process GO:0019439 286 0.043
Yeast
b cell differentiation GO:0030183 78 0.043
lymphocyte differentiation GO:0030098 242 0.043
respiratory system development GO:0060541 190 0.042
organelle fission GO:0048285 170 0.042
rna processing GO:0006396 105 0.041
oocyte construction GO:0007308 2 0.041
t cell activation GO:0042110 289 0.041
cell division GO:0051301 120 0.041
microtubule based process GO:0007017 236 0.041
positive regulation of leukocyte differentiation GO:1902107 86 0.041
limb morphogenesis GO:0035108 149 0.039
regulation of cytokine production GO:0001817 266 0.039
activation of immune response GO:0002253 138 0.039
oocyte axis specification GO:0007309 2 0.038
regulation of defense response GO:0031347 233 0.038
wound healing GO:0042060 157 0.037
respiratory tube development GO:0030323 167 0.037
cellular amine metabolic process GO:0044106 44 0.036
epithelial tube formation GO:0072175 130 0.036
positive regulation of lymphocyte activation GO:0051251 140 0.036
protein ubiquitination GO:0016567 171 0.035
Yeast
peptidyl amino acid modification GO:0018193 336 0.035
Yeast
gland development GO:0048732 330 0.034
spermatid differentiation GO:0048515 115 0.033
negative regulation of protein modification process GO:0031400 163 0.033
Yeast
regulation of cellular amino acid metabolic process GO:0006521 5 0.033
response to oxidative stress GO:0006979 123 0.033
protein localization to nucleus GO:0034504 121 0.033
amine metabolic process GO:0009308 45 0.033
protein acylation GO:0043543 64 0.033
Yeast
regulation of cell cycle process GO:0010564 160 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
cytoplasmic transport GO:0016482 234 0.032
methylation GO:0032259 134 0.031
central nervous system neuron differentiation GO:0021953 162 0.031
regulation of cellular ketone metabolic process GO:0010565 66 0.031
digestive system development GO:0055123 200 0.031
negative regulation of cellular component organization GO:0051129 194 0.030
Yeast
multicellular organism growth GO:0035264 161 0.030
negative regulation of protein maturation GO:1903318 79 0.030
innate immune response GO:0045087 157 0.030
negative regulation of molecular function GO:0044092 258 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
regulation of proteolysis GO:0030162 164 0.030
tube closure GO:0060606 91 0.029
negative regulation of proteolysis GO:0045861 74 0.029
organic cyclic compound catabolic process GO:1901361 295 0.029
Yeast
positive regulation of cytokine production GO:0001819 174 0.028
regulation of cell division GO:0051302 76 0.028
protein maturation GO:0051604 176 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.028
Yeast
regulation of innate immune response GO:0045088 91 0.027
regulation of neuron differentiation GO:0045664 281 0.027
hematopoietic progenitor cell differentiation GO:0002244 143 0.027
regulation of hydrolase activity GO:0051336 246 0.027
skin development GO:0043588 220 0.027
lung development GO:0030324 164 0.026
angiogenesis GO:0001525 201 0.026
cytokine production GO:0001816 319 0.026
regulation of cell cycle GO:0051726 281 0.026
cell maturation GO:0048469 127 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.026
Yeast
rho protein signal transduction GO:0007266 32 0.026
stem cell differentiation GO:0048863 268 0.026
embryonic placenta development GO:0001892 98 0.026
dendrite development GO:0016358 115 0.026
lymphocyte proliferation GO:0046651 164 0.025
multi multicellular organism process GO:0044706 109 0.025
positive regulation of innate immune response GO:0045089 80 0.025
regulation of nucleoside metabolic process GO:0009118 130 0.024
regulation of response to wounding GO:1903034 189 0.024
regulation of nuclear division GO:0051783 56 0.024
regulation of leukocyte differentiation GO:1902105 159 0.024
immune effector process GO:0002252 321 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
regulation of t cell activation GO:0050863 170 0.024
neural tube formation GO:0001841 108 0.023
cellular response to cytokine stimulus GO:0071345 189 0.023
morphogenesis of embryonic epithelium GO:0016331 159 0.023
cellular response to molecule of bacterial origin GO:0071219 83 0.023
chromosome segregation GO:0007059 48 0.023
positive regulation of programmed cell death GO:0043068 218 0.023
regulation of peptidase activity GO:0052547 96 0.023
positive regulation of immune effector process GO:0002699 107 0.023
epithelial tube morphogenesis GO:0060562 303 0.023
regulation of cell motility GO:2000145 236 0.023
regulation of cellular amine metabolic process GO:0033238 20 0.022
sensory organ morphogenesis GO:0090596 242 0.022
regulation of kinase activity GO:0043549 249 0.022
regulation of endopeptidase activity GO:0052548 89 0.022
developmental maturation GO:0021700 193 0.022
cellular response to abiotic stimulus GO:0071214 56 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
Yeast
i kappab kinase nf kappab signaling GO:0007249 85 0.022
regulation of protein maturation GO:1903317 96 0.022
regulation of chromatin modification GO:1903308 57 0.022
Yeast
oocyte development GO:0048599 33 0.022
protein modification by small protein conjugation GO:0032446 187 0.021
Yeast
regulation of apoptotic signaling pathway GO:2001233 197 0.021
transmembrane transport GO:0055085 412 0.021
skeletal system development GO:0001501 356 0.021
macromolecule methylation GO:0043414 120 0.021
protein alkylation GO:0008213 81 0.021
peptidyl lysine modification GO:0018205 77 0.021
Yeast
oocyte differentiation GO:0009994 35 0.021
cellular metal ion homeostasis GO:0006875 151 0.021
positive regulation of defense response GO:0031349 124 0.021
t cell receptor signaling pathway GO:0050852 46 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.020
mitotic cell cycle process GO:1903047 159 0.020
neural tube closure GO:0001843 90 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
Yeast
regulation of translation GO:0006417 71 0.020
stem cell development GO:0048864 219 0.020
embryonic skeletal system development GO:0048706 120 0.020
regulation of organ morphogenesis GO:2000027 144 0.020
fat cell differentiation GO:0045444 160 0.020
primary neural tube formation GO:0014020 95 0.020
small gtpase mediated signal transduction GO:0007264 97 0.020
negative regulation of protein processing GO:0010955 79 0.020
digestive tract development GO:0048565 190 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
cellular homeostasis GO:0019725 240 0.020
blood vessel morphogenesis GO:0048514 285 0.019
mrna processing GO:0006397 63 0.019
regulation of protein kinase activity GO:0045859 232 0.019
protein methylation GO:0006479 81 0.019
appendage development GO:0048736 166 0.019
developmental growth involved in morphogenesis GO:0060560 138 0.019
mitotic chromosome condensation GO:0007076 1 0.019
protein processing GO:0016485 163 0.019
heart morphogenesis GO:0003007 178 0.019
regulation of chromatin silencing GO:0031935 2 0.019
embryonic organ morphogenesis GO:0048562 276 0.019
neuron projection guidance GO:0097485 141 0.018
regulation of mitotic cell cycle phase transition GO:1901990 73 0.018
spermatid development GO:0007286 108 0.018
actin filament based movement GO:0030048 23 0.018
apoptotic signaling pathway GO:0097190 306 0.018
peptidyl serine modification GO:0018209 83 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
cytokine mediated signaling pathway GO:0019221 115 0.018
digestive tract morphogenesis GO:0048546 147 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
secretory granule organization GO:0033363 20 0.018
microtubule cytoskeleton organization GO:0000226 157 0.018
limb development GO:0060173 166 0.018
negative regulation of lymphocyte activation GO:0051250 91 0.017
peptidyl serine phosphorylation GO:0018105 74 0.017
erythrocyte differentiation GO:0030218 88 0.017
response to lipopolysaccharide GO:0032496 128 0.017
ras protein signal transduction GO:0007265 77 0.017
protein autophosphorylation GO:0046777 61 0.017
female gamete generation GO:0007292 74 0.017
cellular lipid metabolic process GO:0044255 323 0.017
meiotic cell cycle GO:0051321 122 0.017
leukocyte proliferation GO:0070661 172 0.017
tube formation GO:0035148 140 0.017
cellular response to biotic stimulus GO:0071216 92 0.017
appendage morphogenesis GO:0035107 149 0.017
immune response regulating signaling pathway GO:0002764 125 0.017
spongiotrophoblast layer development GO:0060712 15 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.017
activation of nf kappab inducing kinase activity GO:0007250 4 0.017
mitotic cell cycle GO:0000278 195 0.017
establishment of planar polarity GO:0001736 28 0.017
negative regulation of cellular catabolic process GO:0031330 47 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
regulation of circadian rhythm GO:0042752 58 0.016
muscle cell differentiation GO:0042692 261 0.016
lactation GO:0007595 25 0.016
osteoclast differentiation GO:0030316 62 0.016
placenta development GO:0001890 140 0.016
positive regulation of cell death GO:0010942 224 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
Yeast
multicellular organismal homeostasis GO:0048871 164 0.016
establishment of tissue polarity GO:0007164 28 0.016
positive regulation of cell activation GO:0050867 158 0.016
positive regulation of nervous system development GO:0051962 221 0.016
regulation of myeloid cell differentiation GO:0045637 96 0.016
lipid localization GO:0010876 126 0.016
macromolecule catabolic process GO:0009057 281 0.016
cell type specific apoptotic process GO:0097285 268 0.016
positive regulation of cell development GO:0010720 237 0.016
meiotic cell cycle process GO:1903046 77 0.016
metal ion homeostasis GO:0055065 189 0.016
regulation of protein catabolic process GO:0042176 108 0.016
lipid biosynthetic process GO:0008610 179 0.015
action potential GO:0001508 78 0.015
negative regulation of organelle organization GO:0010639 90 0.015
Yeast
t cell differentiation GO:0030217 174 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
urogenital system development GO:0001655 261 0.015
regulation of body fluid levels GO:0050878 162 0.015
cation transmembrane transport GO:0098655 266 0.015
fertilization GO:0009566 127 0.015
inflammatory response GO:0006954 244 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.015
immune response activating signal transduction GO:0002757 116 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
dna recombination GO:0006310 92 0.015
positive regulation of antimicrobial humoral response GO:0002760 2 0.015
neural precursor cell proliferation GO:0061351 121 0.014
nucleoside metabolic process GO:0009116 246 0.014
Yeast
epidermis development GO:0008544 187 0.014
regulation of b cell activation GO:0050864 81 0.014
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
negative regulation of hydrolase activity GO:0051346 71 0.014
protein oligomerization GO:0051259 67 0.014
nitrogen compound transport GO:0071705 271 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
regulation of cell projection organization GO:0031344 206 0.014
regulation of protein stability GO:0031647 52 0.014
morphogenesis of a branching epithelium GO:0061138 193 0.014
nucleobase containing small molecule metabolic process GO:0055086 352 0.014
Yeast
anatomical structure homeostasis GO:0060249 145 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
neuronal action potential GO:0019228 54 0.014
regulation of protein processing GO:0070613 96 0.014
ncrna 3 end processing GO:0043628 2 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
Yeast
cellular response to interferon gamma GO:0071346 25 0.014
actin cytoskeleton organization GO:0030036 220 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
development of primary sexual characteristics GO:0045137 143 0.014
heterocycle catabolic process GO:0046700 280 0.014
Yeast
cation homeostasis GO:0055080 212 0.013
regulation of cellular response to stress GO:0080135 159 0.013
gastrulation GO:0007369 116 0.013
lymphocyte homeostasis GO:0002260 64 0.013
genetic imprinting GO:0071514 27 0.013
response to radiation GO:0009314 165 0.013
oogenesis GO:0048477 56 0.013
maintenance of location GO:0051235 89 0.013
cellular ketone metabolic process GO:0042180 84 0.013
apical constriction GO:0003383 4 0.013
response to organonitrogen compound GO:0010243 246 0.013
regulation of chromosome organization GO:0033044 83 0.013
Yeast
cellular chemical homeostasis GO:0055082 215 0.013
cell fate commitment GO:0045165 210 0.013
embryonic appendage morphogenesis GO:0035113 126 0.013
cation transport GO:0006812 399 0.013
regulation of adaptive immune response GO:0002819 90 0.013
negative regulation of cellular protein catabolic process GO:1903363 22 0.013
dna conformation change GO:0071103 37 0.013
Yeast
tissue homeostasis GO:0001894 115 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
forebrain development GO:0030900 302 0.013
mesenchyme development GO:0060485 152 0.013
embryonic limb morphogenesis GO:0030326 126 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
Yeast
regulation of secretion GO:0051046 274 0.013
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.013
response to light stimulus GO:0009416 135 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.012
Yeast
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
leukocyte homeostasis GO:0001776 79 0.012
negative regulation of nervous system development GO:0051961 156 0.012
epithelial cell development GO:0002064 159 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
regulation of proteasomal protein catabolic process GO:0061136 46 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
circadian regulation of gene expression GO:0032922 48 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
cardiac chamber morphogenesis GO:0003206 93 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
regulation of protein localization GO:0032880 231 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
intermediate filament based process GO:0045103 27 0.012
rna interference GO:0016246 2 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
skeletal system morphogenesis GO:0048705 203 0.012
negative regulation of cell development GO:0010721 169 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
Yeast
cellular response to lipid GO:0071396 145 0.012
chemotaxis GO:0006935 247 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
Yeast
posttranscriptional gene silencing by rna GO:0035194 10 0.012
wnt signaling pathway GO:0016055 188 0.012
rna polyadenylation GO:0043631 6 0.011
negative regulation of protein catabolic process GO:0042177 36 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
stem cell maintenance GO:0019827 130 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
Yeast
morphogenesis of a polarized epithelium GO:0001738 37 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
locomotory behavior GO:0007626 195 0.011
mrna metabolic process GO:0016071 84 0.011
mesenchymal cell development GO:0014031 93 0.011
antigen receptor mediated signaling pathway GO:0050851 64 0.011
regulation of production of molecular mediator of immune response GO:0002700 65 0.011
sensory perception GO:0007600 245 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
asymmetric neuroblast division GO:0055059 1 0.011
regulation of hormone levels GO:0010817 211 0.011
positive regulation of leukocyte mediated immunity GO:0002705 70 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.011
positive regulation of growth GO:0045927 104 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
Yeast
organic hydroxy compound transport GO:0015850 93 0.011
regulation of system process GO:0044057 200 0.011
body fluid secretion GO:0007589 53 0.011
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.011
cellular response to external stimulus GO:0071496 88 0.010
regulation of lymphocyte differentiation GO:0045619 107 0.010
natural killer cell activation GO:0030101 44 0.010
purine containing compound metabolic process GO:0072521 311 0.010
Yeast
ear development GO:0043583 200 0.010
lipid transport GO:0006869 98 0.010
interspecies interaction between organisms GO:0044419 83 0.010
regulation of response to dna damage stimulus GO:2001020 34 0.010
purine containing compound biosynthetic process GO:0072522 70 0.010
multi organism behavior GO:0051705 62 0.010
regulation of cell migration GO:0030334 219 0.010
regulation of neural precursor cell proliferation GO:2000177 70 0.010
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.010
protein deacetylation GO:0006476 32 0.010

Chd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.037
cancer DOID:162 0 0.023
organ system cancer DOID:0050686 0 0.014
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011
sensory system disease DOID:0050155 0 0.010