Mus musculus

0 known processes

Dr1

down-regulator of transcription 1

(Aliases: Dr1l,1700121L09Rik,NC2beta,NC2)

Dr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleoside phosphate metabolic process GO:0006753 338 0.148
nucleobase containing small molecule metabolic process GO:0055086 352 0.108
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.093
nucleotide metabolic process GO:0009117 332 0.093
purine containing compound metabolic process GO:0072521 311 0.088
ribonucleotide metabolic process GO:0009259 291 0.080
aromatic compound catabolic process GO:0019439 286 0.080
purine nucleotide metabolic process GO:0006163 302 0.079
ribonucleoside triphosphate catabolic process GO:0009203 199 0.079
purine ribonucleotide metabolic process GO:0009150 290 0.075
organic cyclic compound catabolic process GO:1901361 295 0.074
protein modification by small protein conjugation GO:0032446 187 0.073
cytoplasmic transport GO:0016482 234 0.072
regulation of ras gtpase activity GO:0032318 88 0.069
heterocycle catabolic process GO:0046700 280 0.066
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.061
ribose phosphate metabolic process GO:0019693 291 0.061
nucleoside phosphate catabolic process GO:1901292 222 0.060
glycosyl compound catabolic process GO:1901658 206 0.060
gtp catabolic process GO:0006184 143 0.057
gtp metabolic process GO:0046039 144 0.056
activation of adenylate cyclase activity GO:0007190 4 0.056
nucleoside triphosphate metabolic process GO:0009141 230 0.052
mitotic cell cycle process GO:1903047 159 0.050
limb morphogenesis GO:0035108 149 0.049
purine nucleoside triphosphate catabolic process GO:0009146 203 0.047
regulation of cell motility GO:2000145 236 0.046
guanosine containing compound metabolic process GO:1901068 144 0.046
glycosyl compound metabolic process GO:1901657 246 0.045
regulation of cell size GO:0008361 72 0.045
nucleoside catabolic process GO:0009164 206 0.045
nucleoside phosphate biosynthetic process GO:1901293 79 0.044
endomembrane system organization GO:0010256 147 0.044
protein localization to organelle GO:0033365 185 0.044
nucleoside metabolic process GO:0009116 246 0.043
positive regulation of nucleotide metabolic process GO:0045981 114 0.043
regulation of cellular component size GO:0032535 121 0.043
purine nucleoside catabolic process GO:0006152 205 0.042
ribonucleoside metabolic process GO:0009119 245 0.042
ribonucleoside triphosphate metabolic process GO:0009199 220 0.041
organonitrogen compound catabolic process GO:1901565 264 0.040
regulation of purine nucleotide catabolic process GO:0033121 122 0.039
skeletal system development GO:0001501 356 0.038
membrane organization GO:0061024 245 0.038
regulation of protein transport GO:0051223 163 0.038
osteoclast differentiation GO:0030316 62 0.038
protein modification by small protein conjugation or removal GO:0070647 207 0.037
regulation of myeloid leukocyte differentiation GO:0002761 58 0.037
camp metabolic process GO:0046058 40 0.036
central nervous system neuron differentiation GO:0021953 162 0.036
regulation of system process GO:0044057 200 0.036
carbohydrate derivative biosynthetic process GO:1901137 183 0.036
myeloid cell differentiation GO:0030099 233 0.036
rho protein signal transduction GO:0007266 32 0.035
purine containing compound catabolic process GO:0072523 213 0.035
nucleoside triphosphate catabolic process GO:0009143 205 0.034
regulation of purine nucleotide metabolic process GO:1900542 169 0.034
spermatogenesis GO:0007283 284 0.034
ossification GO:0001503 216 0.032
regulation of gtp catabolic process GO:0033124 113 0.032
regulation of neuron differentiation GO:0045664 281 0.032
regulation of cellular catabolic process GO:0031329 242 0.032
establishment of endothelial blood brain barrier GO:0014045 3 0.032
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.031
protein ubiquitination GO:0016567 171 0.030
positive regulation of apoptotic signaling pathway GO:2001235 95 0.030
cellular amino acid metabolic process GO:0006520 103 0.030
regulation of nucleotide catabolic process GO:0030811 122 0.030
transmission of nerve impulse GO:0019226 76 0.030
purine nucleoside metabolic process GO:0042278 241 0.030
myeloid leukocyte differentiation GO:0002573 119 0.029
purine nucleotide catabolic process GO:0006195 211 0.029
positive regulation of nucleoside metabolic process GO:0045979 91 0.028
morphogenesis of a branching structure GO:0001763 203 0.028
ubiquitin dependent protein catabolic process GO:0006511 129 0.028
epithelial tube morphogenesis GO:0060562 303 0.028
regulation of nucleotide metabolic process GO:0006140 169 0.028
multicellular organism growth GO:0035264 161 0.028
organophosphate catabolic process GO:0046434 232 0.028
camera type eye development GO:0043010 266 0.027
cyclic purine nucleotide metabolic process GO:0052652 43 0.027
regulation of body fluid levels GO:0050878 162 0.027
cellular amine metabolic process GO:0044106 44 0.027
morphogenesis of a branching epithelium GO:0061138 193 0.027
cellular lipid metabolic process GO:0044255 323 0.027
purine ribonucleoside metabolic process GO:0046128 241 0.027
carbohydrate derivative catabolic process GO:1901136 231 0.027
ribonucleoside catabolic process GO:0042454 206 0.027
positive regulation of gtp catabolic process GO:0033126 85 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.026
posttranscriptional regulation of gene expression GO:0010608 155 0.026
guanosine containing compound catabolic process GO:1901069 144 0.025
regulation of camp metabolic process GO:0030814 30 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
cell type specific apoptotic process GO:0097285 268 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
cyclic nucleotide biosynthetic process GO:0009190 44 0.024
regulation of neuron projection development GO:0010975 169 0.024
ribonucleotide catabolic process GO:0009261 208 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.024
establishment of glial blood brain barrier GO:0060857 2 0.024
positive regulation of cell development GO:0010720 237 0.023
regulation of cytoplasmic transport GO:1903649 112 0.023
organophosphate biosynthetic process GO:0090407 122 0.023
positive regulation of gtpase activity GO:0043547 85 0.023
compound eye development GO:0048749 1 0.023
regulation of secretion GO:0051046 274 0.023
regulation of secretion by cell GO:1903530 249 0.022
regulation of anatomical structure size GO:0090066 178 0.022
leukocyte differentiation GO:0002521 342 0.022
lipid biosynthetic process GO:0008610 179 0.022
regulation of nucleoside metabolic process GO:0009118 130 0.022
actin cytoskeleton organization GO:0030036 220 0.021
amine metabolic process GO:0009308 45 0.021
cellular ketone metabolic process GO:0042180 84 0.021
cyclic nucleotide metabolic process GO:0009187 59 0.021
peptidyl amino acid modification GO:0018193 336 0.021
asymmetric neuroblast division GO:0055059 1 0.020
ras protein signal transduction GO:0007265 77 0.020
neuronal action potential GO:0019228 54 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
nucleotide biosynthetic process GO:0009165 78 0.020
regulation of hormone levels GO:0010817 211 0.020
retinal cone cell development GO:0046549 8 0.020
maintenance of protein location in nucleus GO:0051457 2 0.020
g protein coupled receptor signaling pathway GO:0007186 243 0.020
regulation of lyase activity GO:0051339 13 0.020
proteasomal protein catabolic process GO:0010498 98 0.020
skeletal system morphogenesis GO:0048705 203 0.019
regulation of protein localization GO:0032880 231 0.019
regulation of cell projection organization GO:0031344 206 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
positive regulation of secretion by cell GO:1903532 114 0.019
regulation of heart contraction GO:0008016 77 0.018
response to radiation GO:0009314 165 0.018
positive regulation of osteoblast differentiation GO:0045669 34 0.018
establishment of protein localization to organelle GO:0072594 118 0.018
morphogenesis of embryonic epithelium GO:0016331 159 0.018
nuclear division GO:0000280 158 0.018
embryonic skeletal system development GO:0048706 120 0.018
forebrain development GO:0030900 302 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.018
limb development GO:0060173 166 0.018
stem cell proliferation GO:0072089 117 0.018
asymmetric stem cell division GO:0098722 3 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.017
cell cycle switching GO:0060184 1 0.017
gland development GO:0048732 330 0.017
positive regulation of leukocyte differentiation GO:1902107 86 0.017
positive regulation of secretion GO:0051047 130 0.017
endocytosis GO:0006897 168 0.017
negative regulation of dna replication GO:0008156 4 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.017
regulation of osteoblast differentiation GO:0045667 67 0.017
regulation of protein catabolic process GO:0042176 108 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
sensory perception GO:0007600 245 0.017
regulation of myeloid cell differentiation GO:0045637 96 0.017
nucleotide catabolic process GO:0009166 217 0.017
regulation of hydrolase activity GO:0051336 246 0.016
centromere complex assembly GO:0034508 3 0.016
regulation of cellular amine metabolic process GO:0033238 20 0.016
circulatory system process GO:0003013 197 0.016
endocrine system development GO:0035270 98 0.016
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.016
gliogenesis GO:0042063 141 0.016
apoptotic signaling pathway GO:0097190 306 0.016
response to organonitrogen compound GO:0010243 246 0.016
regulation of cellular ketone metabolic process GO:0010565 66 0.016
secretory granule organization GO:0033363 20 0.016
blood circulation GO:0008015 195 0.016
regulation of intracellular protein transport GO:0033157 82 0.016
cellular response to inorganic substance GO:0071241 37 0.015
positive regulation of nervous system development GO:0051962 221 0.015
connective tissue development GO:0061448 179 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
retina development in camera type eye GO:0060041 119 0.015
microtubule based process GO:0007017 236 0.015
embryonic appendage morphogenesis GO:0035113 126 0.015
maintenance of protein localization in organelle GO:0072595 2 0.015
blood vessel morphogenesis GO:0048514 285 0.015
embryonic limb morphogenesis GO:0030326 126 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
neural precursor cell proliferation GO:0061351 121 0.015
hormone secretion GO:0046879 128 0.015
ribonucleoprotein complex subunit organization GO:0071826 28 0.015
appendage development GO:0048736 166 0.015
heart process GO:0003015 94 0.015
multicellular organismal signaling GO:0035637 91 0.014
visual perception GO:0007601 52 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
respiratory system development GO:0060541 190 0.014
multi organism behavior GO:0051705 62 0.014
oxidation reduction process GO:0055114 342 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
appendage morphogenesis GO:0035107 149 0.014
maintenance of location GO:0051235 89 0.014
dna metabolic process GO:0006259 303 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
photoreceptor cell development GO:0042461 40 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
carbohydrate metabolic process GO:0005975 230 0.013
cell fate determination GO:0001709 32 0.013
bone development GO:0060348 120 0.013
angiogenesis GO:0001525 201 0.013
regulation of blood circulation GO:1903522 93 0.013
regulation of protein stability GO:0031647 52 0.013
regulation of organelle organization GO:0033043 289 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
regulation of protein ubiquitination GO:0031396 52 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
eye photoreceptor cell differentiation GO:0001754 41 0.012
branching morphogenesis of an epithelial tube GO:0048754 159 0.012
sensory perception of umami taste GO:0050917 4 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
positive regulation of protein transport GO:0051222 93 0.012
regulation of cell migration GO:0030334 219 0.012
positive regulation of camp metabolic process GO:0030816 19 0.012
response to inorganic substance GO:0010035 96 0.012
cellular protein catabolic process GO:0044257 155 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.012
dna replication GO:0006260 52 0.012
oocyte construction GO:0007308 2 0.012
skin development GO:0043588 220 0.012
cellular homeostasis GO:0019725 240 0.012
action potential GO:0001508 78 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
fat cell differentiation GO:0045444 160 0.012
regulation of cellular amino acid metabolic process GO:0006521 5 0.012
regulation of establishment of protein localization GO:0070201 181 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
anatomical structure homeostasis GO:0060249 145 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
regulation of cell adhesion GO:0030155 154 0.011
mitotic cell cycle GO:0000278 195 0.011
negative regulation of cell cycle GO:0045786 123 0.011
response to organic cyclic compound GO:0014070 198 0.011
muscle cell differentiation GO:0042692 261 0.011
rna processing GO:0006396 105 0.011
cell maturation GO:0048469 127 0.011
regulation of ossification GO:0030278 112 0.011
vesicle organization GO:0016050 60 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
heart contraction GO:0060047 93 0.011
sphingolipid metabolic process GO:0006665 45 0.010
macromolecule catabolic process GO:0009057 281 0.010
embryonic digit morphogenesis GO:0042733 56 0.010
lung development GO:0030324 164 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010
homeostasis of number of cells GO:0048872 210 0.010
regulation of protein kinase activity GO:0045859 232 0.010
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.010

Dr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.059
disease of anatomical entity DOID:7 0 0.059
eye and adnexa disease DOID:1492 0 0.059
nervous system disease DOID:863 0 0.059
eye disease DOID:5614 0 0.045
retinal disease DOID:5679 0 0.023
retinal degeneration DOID:8466 0 0.023
central nervous system disease DOID:331 0 0.017
neurodegenerative disease DOID:1289 0 0.017
brain disease DOID:936 0 0.014