Mus musculus

63 known processes

Adh5

alcohol dehydrogenase 5 (class III), chi polypeptide

(Aliases: Adh3,GSNOR,Adh-5)

Adh5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.346
cellular amino acid metabolic process GO:0006520 103 0.164
cellular lipid metabolic process GO:0044255 323 0.104
nucleobase containing small molecule metabolic process GO:0055086 352 0.100
alpha amino acid metabolic process GO:1901605 59 0.099
apoptotic signaling pathway GO:0097190 306 0.098
coenzyme biosynthetic process GO:0009108 23 0.096
nucleotide metabolic process GO:0009117 332 0.089
carboxylic acid catabolic process GO:0046395 51 0.086
ribose phosphate metabolic process GO:0019693 291 0.085
small molecule catabolic process GO:0044282 71 0.082
organic acid catabolic process GO:0016054 51 0.081
amine metabolic process GO:0009308 45 0.079
cellular ketone metabolic process GO:0042180 84 0.077
monocarboxylic acid metabolic process GO:0032787 191 0.076
Mouse
coenzyme metabolic process GO:0006732 52 0.074
purine ribonucleotide metabolic process GO:0009150 290 0.067
nucleoside phosphate metabolic process GO:0006753 338 0.067
small molecule biosynthetic process GO:0044283 132 0.063
dna metabolic process GO:0006259 303 0.063
purine containing compound metabolic process GO:0072521 311 0.062
aromatic compound catabolic process GO:0019439 286 0.062
cellular nitrogen compound catabolic process GO:0044270 280 0.059
organonitrogen compound biosynthetic process GO:1901566 192 0.059
fatty acid metabolic process GO:0006631 121 0.058
ribonucleoside metabolic process GO:0009119 245 0.058
regulation of cellular amino acid metabolic process GO:0006521 5 0.056
cellular amine metabolic process GO:0044106 44 0.056
glycosyl compound metabolic process GO:1901657 246 0.055
purine nucleotide metabolic process GO:0006163 302 0.055
acyl coa metabolic process GO:0006637 19 0.053
nucleoside metabolic process GO:0009116 246 0.052
ribonucleotide metabolic process GO:0009259 291 0.052
organic hydroxy compound metabolic process GO:1901615 203 0.051
Mouse Rat
regulation of cellular amine metabolic process GO:0033238 20 0.051
cofactor metabolic process GO:0051186 80 0.048
purine nucleoside metabolic process GO:0042278 241 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
male gamete generation GO:0048232 285 0.045
regulation of mapk cascade GO:0043408 248 0.045
cytoplasmic transport GO:0016482 234 0.045
alpha amino acid biosynthetic process GO:1901607 15 0.044
carboxylic acid biosynthetic process GO:0046394 86 0.043
positive regulation of protein modification process GO:0031401 299 0.043
regulation of cytoplasmic transport GO:1903649 112 0.043
regulation of cellular ketone metabolic process GO:0010565 66 0.041
organic cyclic compound catabolic process GO:1901361 295 0.040
purine ribonucleoside metabolic process GO:0046128 241 0.040
organonitrogen compound catabolic process GO:1901565 264 0.039
response to oxygen radical GO:0000305 16 0.039
ribonucleotide catabolic process GO:0009261 208 0.039
ribonucleoside triphosphate metabolic process GO:0009199 220 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.038
mapk cascade GO:0000165 281 0.037
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
myeloid cell differentiation GO:0030099 233 0.037
nucleoside triphosphate metabolic process GO:0009141 230 0.037
nucleoside monophosphate metabolic process GO:0009123 85 0.036
homeostasis of number of cells GO:0048872 210 0.035
male sex differentiation GO:0046661 109 0.035
cellular response to dna damage stimulus GO:0006974 207 0.035
regulation of protein kinase activity GO:0045859 232 0.035
cellular modified amino acid metabolic process GO:0006575 63 0.034
protein maturation GO:0051604 176 0.034
regulation of transferase activity GO:0051338 263 0.033
aldehyde catabolic process GO:0046185 4 0.033
gland development GO:0048732 330 0.033
cellular amino acid biosynthetic process GO:0008652 22 0.033
reactive oxygen species metabolic process GO:0072593 84 0.033
negative regulation of immune system process GO:0002683 209 0.033
nitrogen compound transport GO:0071705 271 0.033
regulation of cellular response to stress GO:0080135 159 0.033
regulation of apoptotic signaling pathway GO:2001233 197 0.032
organophosphate catabolic process GO:0046434 232 0.032
immune effector process GO:0002252 321 0.032
steroid metabolic process GO:0008202 119 0.032
purine nucleoside triphosphate metabolic process GO:0009144 226 0.032
inflammatory response GO:0006954 244 0.031
innate immune response GO:0045087 157 0.031
response to oxidative stress GO:0006979 123 0.031
spermatogenesis GO:0007283 284 0.031
regulation of response to wounding GO:1903034 189 0.031
response to lipopolysaccharide GO:0032496 128 0.030
regulation of membrane potential GO:0042391 192 0.030
cellular lipid catabolic process GO:0044242 52 0.030
intracellular protein transport GO:0006886 204 0.030
transmembrane transport GO:0055085 412 0.029
macromolecule catabolic process GO:0009057 281 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.029
regulation of cellular catabolic process GO:0031329 242 0.029
negative regulation of molecular function GO:0044092 258 0.029
sulfur compound metabolic process GO:0006790 100 0.029
cytokine production GO:0001816 319 0.028
response to organonitrogen compound GO:0010243 246 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
mitochondrion organization GO:0007005 134 0.028
cellular response to lipopolysaccharide GO:0071222 77 0.027
regulation of reactive oxygen species metabolic process GO:2000377 40 0.027
development of primary male sexual characteristics GO:0046546 88 0.027
anatomical structure homeostasis GO:0060249 145 0.027
regulation of kinase activity GO:0043549 249 0.027
organic acid biosynthetic process GO:0016053 86 0.026
regulation of cytokine production GO:0001817 266 0.026
cellular homeostasis GO:0019725 240 0.026
lymphocyte mediated immunity GO:0002449 139 0.026
leukocyte differentiation GO:0002521 342 0.025
intrinsic apoptotic signaling pathway GO:0097193 132 0.025
extrinsic apoptotic signaling pathway GO:0097191 126 0.025
regulation of cell activation GO:0050865 289 0.025
regulation of lymphocyte activation GO:0051249 240 0.025
tissue homeostasis GO:0001894 115 0.025
protein localization to organelle GO:0033365 185 0.025
regulation of protein transport GO:0051223 163 0.024
male gonad development GO:0008584 88 0.024
regulation of defense response GO:0031347 233 0.024
cofactor biosynthetic process GO:0051188 41 0.024
multicellular organismal homeostasis GO:0048871 164 0.024
cellular response to biotic stimulus GO:0071216 92 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
cation transport GO:0006812 399 0.023
negative regulation of cell activation GO:0050866 111 0.023
t cell activation GO:0042110 289 0.023
regulation of hormone levels GO:0010817 211 0.023
Mouse
regulation of t cell activation GO:0050863 170 0.023
lipid catabolic process GO:0016042 69 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
cellular response to molecule of bacterial origin GO:0071219 83 0.022
response to inorganic substance GO:0010035 96 0.022
regulation of protein localization GO:0032880 231 0.022
cellular response to lipid GO:0071396 145 0.022
wound healing GO:0042060 157 0.022
fatty acid catabolic process GO:0009062 25 0.022
cell type specific apoptotic process GO:0097285 268 0.022
leukocyte proliferation GO:0070661 172 0.022
leukocyte mediated immunity GO:0002443 174 0.021
gonad development GO:0008406 141 0.021
4 hydroxyproline metabolic process GO:0019471 5 0.021
regulation of organelle organization GO:0033043 289 0.021
regulation of removal of superoxide radicals GO:2000121 4 0.021
reactive oxygen species biosynthetic process GO:1903409 8 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.021
development of primary sexual characteristics GO:0045137 143 0.021
interleukin 8 production GO:0032637 4 0.020
response to extracellular stimulus GO:0009991 127 0.020
hormone metabolic process GO:0042445 86 0.020
Mouse
anion transport GO:0006820 177 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
heterocycle catabolic process GO:0046700 280 0.020
nuclear transport GO:0051169 139 0.020
positive regulation of mapk cascade GO:0043410 170 0.020
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.020
action potential GO:0001508 78 0.020
nucleotide catabolic process GO:0009166 217 0.019
energy derivation by oxidation of organic compounds GO:0015980 77 0.019
negative regulation of cell proliferation GO:0008285 296 0.019
cellular response to oxygen radical GO:0071450 14 0.019
nucleoside catabolic process GO:0009164 206 0.019
protein localization to nucleus GO:0034504 121 0.019
alcohol metabolic process GO:0006066 116 0.019
Mouse Rat
negative regulation of phosphate metabolic process GO:0045936 184 0.019
regulation of protein serine threonine kinase activity GO:0071900 157 0.019
generation of precursor metabolites and energy GO:0006091 103 0.019
response to organic cyclic compound GO:0014070 198 0.019
Mouse
ketone catabolic process GO:0042182 3 0.018
ion transmembrane transport GO:0034220 361 0.018
negative regulation of lymphocyte activation GO:0051250 91 0.018
positive regulation of kinase activity GO:0033674 155 0.018
regulation of transmembrane transport GO:0034762 128 0.018
superoxide metabolic process GO:0006801 27 0.018
germ cell development GO:0007281 185 0.018
negative regulation of apoptotic signaling pathway GO:2001234 104 0.018
synaptic transmission GO:0007268 329 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
thioester metabolic process GO:0035383 19 0.018
lymphocyte proliferation GO:0046651 164 0.018
removal of superoxide radicals GO:0019430 12 0.018
regulation of ion transport GO:0043269 215 0.018
regulation of body fluid levels GO:0050878 162 0.018
peptidyl amino acid modification GO:0018193 336 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
protein targeting GO:0006605 143 0.018
neuron death GO:0070997 154 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
positive regulation of cell death GO:0010942 224 0.018
g protein coupled receptor signaling pathway GO:0007186 243 0.018
lipid biosynthetic process GO:0008610 179 0.017
neuron apoptotic process GO:0051402 142 0.017
regulation of leukocyte differentiation GO:1902105 159 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
regulation of intracellular transport GO:0032386 159 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
myeloid cell homeostasis GO:0002262 114 0.017
modification dependent macromolecule catabolic process GO:0043632 133 0.017
atp metabolic process GO:0046034 75 0.017
sensory perception GO:0007600 245 0.017
lymphocyte differentiation GO:0030098 242 0.017
cellular response to extracellular stimulus GO:0031668 81 0.017
regulation of interleukin 8 production GO:0032677 3 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
multicellular organism growth GO:0035264 161 0.017
regulation of epithelial cell proliferation GO:0050678 141 0.016
regulation of secretion by cell GO:1903530 249 0.016
stem cell differentiation GO:0048863 268 0.016
spermatid differentiation GO:0048515 115 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
stress activated protein kinase signaling cascade GO:0031098 81 0.016
cellular response to external stimulus GO:0071496 88 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
epidermis development GO:0008544 187 0.016
cellular alcohol metabolic process GO:0044107 3 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
protein ubiquitination GO:0016567 171 0.016
cation transmembrane transport GO:0098655 266 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.016
urogenital system development GO:0001655 261 0.016
alcohol biosynthetic process GO:0046165 43 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
membrane organization GO:0061024 245 0.016
establishment of protein localization to organelle GO:0072594 118 0.015
regulation of proteolysis GO:0030162 164 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
organic hydroxy compound biosynthetic process GO:1901617 77 0.015
cellular alcohol biosynthetic process GO:0044108 3 0.015
peptidyl serine phosphorylation GO:0018105 74 0.015
regulation of hemostasis GO:1900046 28 0.015
positive regulation of transferase activity GO:0051347 167 0.015
monocarboxylic acid catabolic process GO:0072329 27 0.015
regulation of binding GO:0051098 111 0.015
regulation of hydrolase activity GO:0051336 246 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
skeletal system development GO:0001501 356 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
epithelial cell proliferation GO:0050673 174 0.015
regulation of protein catabolic process GO:0042176 108 0.014
t cell differentiation GO:0030217 174 0.014
negative regulation of t cell activation GO:0050868 65 0.014
protein localization to membrane GO:0072657 108 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
renal system development GO:0072001 225 0.014
epithelial cell development GO:0002064 159 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
regulation of blood coagulation GO:0030193 28 0.014
placenta development GO:0001890 140 0.014
defense response to other organism GO:0098542 197 0.014
cellular response to oxidative stress GO:0034599 76 0.014
extracellular structure organization GO:0043062 148 0.014
monocarboxylic acid biosynthetic process GO:0072330 61 0.014
fat soluble vitamin biosynthetic process GO:0042362 4 0.014
spermatid development GO:0007286 108 0.014
negative regulation of protein modification process GO:0031400 163 0.014
maintenance of location GO:0051235 89 0.013
lipid modification GO:0030258 65 0.013
methylation GO:0032259 134 0.013
forebrain development GO:0030900 302 0.013
regulation of secretion GO:0051046 274 0.013
cellular ion homeostasis GO:0006873 165 0.013
coagulation GO:0050817 78 0.013
cellular protein complex assembly GO:0043623 116 0.013
t cell proliferation GO:0042098 120 0.013
neuronal action potential GO:0019228 54 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.013
protein processing GO:0016485 163 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
multi multicellular organism process GO:0044706 109 0.013
blood coagulation GO:0007596 76 0.013
fatty acid oxidation GO:0019395 28 0.013
cellular protein catabolic process GO:0044257 155 0.013
cellular respiration GO:0045333 38 0.013
extracellular matrix organization GO:0030198 147 0.013
transmission of nerve impulse GO:0019226 76 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
regulation of protein stability GO:0031647 52 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
hemostasis GO:0007599 78 0.013
organic hydroxy compound transport GO:0015850 93 0.013
regulation of intracellular protein transport GO:0033157 82 0.013
kidney development GO:0001822 213 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.013
ras protein signal transduction GO:0007265 77 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
positive regulation of interleukin 8 production GO:0032757 2 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
divalent inorganic cation transport GO:0072511 178 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
liver development GO:0001889 66 0.012
lipid localization GO:0010876 126 0.012
response to drug GO:0042493 75 0.012
connective tissue development GO:0061448 179 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
macromolecule methylation GO:0043414 120 0.012
regulation of nucleocytoplasmic transport GO:0046822 73 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
peptidyl serine modification GO:0018209 83 0.012
regulation of anatomical structure size GO:0090066 178 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
i kappab kinase nf kappab signaling GO:0007249 85 0.012
positive regulation of secretion GO:0051047 130 0.012
regulation of inflammatory response GO:0050727 147 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.012
locomotory behavior GO:0007626 195 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
regulation of lymphocyte differentiation GO:0045619 107 0.012
negative regulation of leukocyte differentiation GO:1902106 51 0.012
cellular chemical homeostasis GO:0055082 215 0.012
protein secretion GO:0009306 111 0.012
vitamin d3 metabolic process GO:0070640 3 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
positive regulation of map kinase activity GO:0043406 84 0.012
regulation of protein localization to nucleus GO:1900180 60 0.012
neuron migration GO:0001764 122 0.012
primary alcohol metabolic process GO:0034308 11 0.012
Mouse Rat
negative regulation of protein processing GO:0010955 79 0.012
plasma membrane organization GO:0007009 90 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
fatty acid beta oxidation GO:0006635 16 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
regulation of wound healing GO:0061041 40 0.012
cation homeostasis GO:0055080 212 0.012
camera type eye development GO:0043010 266 0.012
regulation of system process GO:0044057 200 0.011
calcium ion transport GO:0006816 159 0.011
regulation of map kinase activity GO:0043405 120 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
response to oxygen levels GO:0070482 62 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
hepaticobiliary system development GO:0061008 67 0.011
heart process GO:0003015 94 0.011
response to reactive oxygen species GO:0000302 56 0.011
calcium ion homeostasis GO:0055074 127 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
asymmetric stem cell division GO:0098722 3 0.011
protein oligomerization GO:0051259 67 0.011
negative regulation of cellular catabolic process GO:0031330 47 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
protein targeting to peroxisome GO:0006625 4 0.011
microtubule based process GO:0007017 236 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
signal transduction by p53 class mediator GO:0072331 51 0.011
lipid oxidation GO:0034440 29 0.011
leukocyte mediated cytotoxicity GO:0001909 62 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
protein import GO:0017038 101 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
regulation of male germ cell proliferation GO:2000254 3 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
amide transport GO:0042886 138 0.011
response to nutrient levels GO:0031667 109 0.011
endomembrane system organization GO:0010256 147 0.011
cellular response to superoxide GO:0071451 14 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
cell killing GO:0001906 67 0.011
multicellular organismal signaling GO:0035637 91 0.011
positive regulation of programmed cell death GO:0043068 218 0.010
skin development GO:0043588 220 0.010
sequestering of calcium ion GO:0051208 18 0.010
regulation of t cell differentiation GO:0045580 83 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
positive regulation of nucleoside metabolic process GO:0045979 91 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
carbohydrate metabolic process GO:0005975 230 0.010
positive regulation of growth GO:0045927 104 0.010
blood circulation GO:0008015 195 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
positive regulation of cytokine production GO:0001819 174 0.010
signal transduction in absence of ligand GO:0038034 55 0.010
regulation of protein ubiquitination GO:0031396 52 0.010
rna processing GO:0006396 105 0.010
regulation of neuron death GO:1901214 134 0.010
regulation of response to biotic stimulus GO:0002831 38 0.010
regulation of feeding behavior GO:0060259 3 0.010
activation of immune response GO:0002253 138 0.010
circulatory system process GO:0003013 197 0.010
activation of mapk activity GO:0000187 59 0.010
positive regulation of apoptotic process GO:0043065 217 0.010
positive regulation of cell development GO:0010720 237 0.010
gtp metabolic process GO:0046039 144 0.010
regulation of cell cycle GO:0051726 281 0.010

Adh5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.032
inherited metabolic disorder DOID:655 0 0.020
disease of cellular proliferation DOID:14566 0 0.016
nervous system disease DOID:863 0 0.015
disease of anatomical entity DOID:7 0 0.015
central nervous system disease DOID:331 0 0.011
neurodegenerative disease DOID:1289 0 0.011
musculoskeletal system disease DOID:17 0 0.011