Mus musculus

9 known processes

Unc13c

unc-13 homolog C (C. elegans)

(Aliases: MGC40770,1500037O19Rik,D9Ertd414e,Munc13-3,Unc13h3,AU019458)

Unc13c biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.126
transmembrane transport GO:0055085 412 0.093
inorganic ion transmembrane transport GO:0098660 234 0.086
inorganic cation transmembrane transport GO:0098662 207 0.063
cation transport GO:0006812 399 0.056
cation transmembrane transport GO:0098655 266 0.054
cellular amino acid metabolic process GO:0006520 103 0.049
synaptic transmission GO:0007268 329 0.042
membrane organization GO:0061024 245 0.041
multicellular organismal signaling GO:0035637 91 0.039
amine metabolic process GO:0009308 45 0.039
action potential GO:0001508 78 0.037
anion transport GO:0006820 177 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.036
cellular amine metabolic process GO:0044106 44 0.035
transmission of nerve impulse GO:0019226 76 0.035
macromolecule catabolic process GO:0009057 281 0.034
learning or memory GO:0007611 148 0.034
regulation of cellular ketone metabolic process GO:0010565 66 0.034
cellular chemical homeostasis GO:0055082 215 0.033
g protein coupled receptor signaling pathway GO:0007186 243 0.033
regulation of membrane potential GO:0042391 192 0.033
nucleotide metabolic process GO:0009117 332 0.033
cellular homeostasis GO:0019725 240 0.032
response to organonitrogen compound GO:0010243 246 0.030
anion transmembrane transport GO:0098656 71 0.030
nucleobase containing small molecule metabolic process GO:0055086 352 0.030
maintenance of location GO:0051235 89 0.030
sensory perception GO:0007600 245 0.030
locomotory behavior GO:0007626 195 0.029
purine nucleotide metabolic process GO:0006163 302 0.029
cellular lipid metabolic process GO:0044255 323 0.028
neuronal action potential GO:0019228 54 0.027
regulation of transmembrane transport GO:0034762 128 0.027
cellular ketone metabolic process GO:0042180 84 0.027
protein localization to membrane GO:0072657 108 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.026
camera type eye development GO:0043010 266 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
peptidyl amino acid modification GO:0018193 336 0.026
calcium ion homeostasis GO:0055074 127 0.026
purine containing compound metabolic process GO:0072521 311 0.025
organic anion transport GO:0015711 137 0.025
cognition GO:0050890 149 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
cellular divalent inorganic cation homeostasis GO:0072503 127 0.024
cation homeostasis GO:0055080 212 0.024
neuron neuron synaptic transmission GO:0007270 69 0.024
Mouse
regulation of cellular catabolic process GO:0031329 242 0.023
calcium ion transport GO:0006816 159 0.023
cell adhesion GO:0007155 329 0.022
nucleoside metabolic process GO:0009116 246 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
response to organic cyclic compound GO:0014070 198 0.022
regulation of organelle organization GO:0033043 289 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
cellular metal ion homeostasis GO:0006875 151 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
apoptotic signaling pathway GO:0097190 306 0.021
regulation of proteolysis GO:0030162 164 0.021
cellular calcium ion homeostasis GO:0006874 119 0.021
endomembrane system organization GO:0010256 147 0.021
metal ion homeostasis GO:0055065 189 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
mapk cascade GO:0000165 281 0.020
regulation of ion transport GO:0043269 215 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
nitrogen compound transport GO:0071705 271 0.020
adult behavior GO:0030534 135 0.020
aromatic compound catabolic process GO:0019439 286 0.019
multicellular organismal response to stress GO:0033555 62 0.019
regulation of purine nucleotide metabolic process GO:1900542 169 0.019
multicellular organism growth GO:0035264 161 0.019
protein catabolic process GO:0030163 221 0.019
cellular ion homeostasis GO:0006873 165 0.019
fertilization GO:0009566 127 0.019
regulation of transferase activity GO:0051338 263 0.019
regulation of secretion GO:0051046 274 0.019
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
forebrain development GO:0030900 302 0.018
learning GO:0007612 98 0.018
axon ensheathment GO:0008366 76 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
positive regulation of mapk cascade GO:0043410 170 0.018
sensory perception of light stimulus GO:0050953 54 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
calcium ion transmembrane transport GO:0070588 85 0.017
retina development in camera type eye GO:0060041 119 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.017
regulation of hydrolase activity GO:0051336 246 0.017
regulation of protein serine threonine kinase activity GO:0071900 157 0.017
engulfment of apoptotic cell GO:0043652 3 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
regulation of purine nucleotide catabolic process GO:0033121 122 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
regulation of hormone levels GO:0010817 211 0.016
regulation of protein catabolic process GO:0042176 108 0.016
regulation of protein localization GO:0032880 231 0.016
positive regulation of protein modification process GO:0031401 299 0.016
ras protein signal transduction GO:0007265 77 0.016
positive regulation of nervous system development GO:0051962 221 0.016
actin cytoskeleton organization GO:0030036 220 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
inorganic anion transmembrane transport GO:0098661 29 0.016
oxidation reduction process GO:0055114 342 0.016
heterocycle catabolic process GO:0046700 280 0.016
positive regulation of transferase activity GO:0051347 167 0.016
endocytosis GO:0006897 168 0.016
Mouse
regulation of kinase activity GO:0043549 249 0.016
cellular macromolecule catabolic process GO:0044265 206 0.015
exocytosis GO:0006887 121 0.015
Mouse Fly
organophosphate catabolic process GO:0046434 232 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
inorganic anion transport GO:0015698 43 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
sensory organ morphogenesis GO:0090596 242 0.015
divalent inorganic cation transport GO:0072511 178 0.015
sequestering of metal ion GO:0051238 19 0.015
cell type specific apoptotic process GO:0097285 268 0.015
organelle localization GO:0051640 179 0.015
Mouse Fly
nucleoside phosphate catabolic process GO:1901292 222 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
sequestering of calcium ion GO:0051208 18 0.015
intracellular protein transport GO:0006886 204 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.014
neurotransmitter transport GO:0006836 76 0.014
Mouse Fly
positive regulation of protein phosphorylation GO:0001934 242 0.014
muscle tissue development GO:0060537 308 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
visual perception GO:0007601 52 0.014
immune effector process GO:0002252 321 0.014
regulation of metal ion transport GO:0010959 106 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
negative regulation of protein modification process GO:0031400 163 0.014
ensheathment of neurons GO:0007272 76 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
oocyte axis specification GO:0007309 2 0.014
cytokine production GO:0001816 319 0.014
regulation of map kinase activity GO:0043405 120 0.014
regulation of system process GO:0044057 200 0.014
glucose homeostasis GO:0042593 128 0.014
regulation of secretion by cell GO:1903530 249 0.014
Mouse
regulation of protein kinase activity GO:0045859 232 0.014
regulation of mapk cascade GO:0043408 248 0.014
amino acid transport GO:0006865 61 0.014
plasma membrane organization GO:0007009 90 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
nucleotide catabolic process GO:0009166 217 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
glycoprotein biosynthetic process GO:0009101 89 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.014
cytoplasmic transport GO:0016482 234 0.013
protein processing GO:0016485 163 0.013
myelination GO:0042552 74 0.013
lipid localization GO:0010876 126 0.013
purine containing compound catabolic process GO:0072523 213 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
positive regulation of kinase activity GO:0033674 155 0.013
microtubule based process GO:0007017 236 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
oocyte construction GO:0007308 2 0.013
fat cell differentiation GO:0045444 160 0.013
spermatogenesis GO:0007283 284 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
striated muscle tissue development GO:0014706 293 0.013
positive regulation of cell development GO:0010720 237 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
gland development GO:0048732 330 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
fatty acid metabolic process GO:0006631 121 0.013
anatomical structure homeostasis GO:0060249 145 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
immune response regulating signaling pathway GO:0002764 125 0.013
protein maturation GO:0051604 176 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
protein ubiquitination GO:0016567 171 0.012
behavioral defense response GO:0002209 28 0.012
actin filament polymerization GO:0030041 44 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
regulation of actin filament based process GO:0032970 99 0.012
cellular protein complex assembly GO:0043623 116 0.012
Mouse
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.012
nuclear division GO:0000280 158 0.012
neuromuscular process GO:0050905 99 0.012
chloride transmembrane transport GO:1902476 24 0.012
negative regulation of molecular function GO:0044092 258 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
carbohydrate metabolic process GO:0005975 230 0.012
sodium ion transmembrane transport GO:0035725 49 0.012
regulation of response to wounding GO:1903034 189 0.012
leukocyte migration GO:0050900 124 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
regulation of synaptic plasticity GO:0048167 87 0.012
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.012
chloride transport GO:0006821 32 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.012
adult locomotory behavior GO:0008344 91 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
memory GO:0007613 58 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
divalent metal ion transport GO:0070838 172 0.011
carbohydrate homeostasis GO:0033500 128 0.011
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
lipid transport GO:0006869 98 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
regulation of homeostatic process GO:0032844 182 0.011
axonogenesis GO:0007409 274 0.011
Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
compound eye development GO:0048749 1 0.011
inclusion body assembly GO:0070841 3 0.011
glycoprotein metabolic process GO:0009100 116 0.011
organic acid transport GO:0015849 101 0.011
intracellular mrna localization GO:0008298 4 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
cellular protein catabolic process GO:0044257 155 0.011
immune response activating signal transduction GO:0002757 116 0.011
regulation of cytokine production GO:0001817 266 0.011
regulation of neuron differentiation GO:0045664 281 0.011
defecation GO:0030421 1 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
nucleoside catabolic process GO:0009164 206 0.011
lateral inhibition GO:0046331 1 0.011
male gamete generation GO:0048232 285 0.011
response to inorganic substance GO:0010035 96 0.011
protein localization to organelle GO:0033365 185 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
homeostasis of number of cells GO:0048872 210 0.011
fear response GO:0042596 33 0.011
activation of immune response GO:0002253 138 0.010
respiratory system development GO:0060541 190 0.010
phospholipid metabolic process GO:0006644 87 0.010
myeloid cell differentiation GO:0030099 233 0.010
carboxylic acid transport GO:0046942 100 0.010
cell recognition GO:0008037 83 0.010
purine nucleotide catabolic process GO:0006195 211 0.010
organelle fission GO:0048285 170 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
inflammatory response GO:0006954 244 0.010
ribonucleotide catabolic process GO:0009261 208 0.010
response to light stimulus GO:0009416 135 0.010
regulation of response to drug GO:2001023 2 0.010
single organism cell adhesion GO:0098602 156 0.010
placenta development GO:0001890 140 0.010
stem cell differentiation GO:0048863 268 0.010
tissue homeostasis GO:0001894 115 0.010
protein targeting GO:0006605 143 0.010
regulation of cell activation GO:0050865 289 0.010
vesicle localization GO:0051648 86 0.010
Mouse Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010

Unc13c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032
central nervous system disease DOID:331 0 0.014
retinal disease DOID:5679 0 0.012
retinal degeneration DOID:8466 0 0.012
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
neurodegenerative disease DOID:1289 0 0.011